New directions for neurodegenerative disease therapy: Using chemical compounds to boost the formation of mutant protein inclusions

Cell Cycle

Volumn 5, Issue 14, 2006, Pages 1477-1480

  Bodner, Ruth A ^a   Housman, David E ^a   Kazantsev, Aleksey G ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Aggregation; Huntington's disease; Inclusion body; Misfolded protein; Neurodegenerative diseases; Parkinson's disease

Indexed keywords

5 [4 (4 CHLOROBENZOYL) 1 PIPERAZINYL] 8 NITROQUINOLINE; ALPHA SYNUCLEIN; CHEMICAL COMPOUND; HUNTINGTIN; MUTANT PROTEIN; NITROQUINOLINE DERIVATIVE; POLYGLUTAMINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; CELL FUNCTION; CELL INCLUSION; CELL PROTECTION; CYTOTOXICITY; DEGENERATIVE DISEASE; HUMAN; HUNTINGTON CHOREA; MEDICAL RESEARCH; NERVE CELL DEGENERATION; NONHUMAN; PARKINSON DISEASE; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE; PROTEIN TARGETING; REVIEW;

EID: 33746265074     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.5.14.2929     Document Type: Review

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