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Volumn 147, Issue 6, 2006, Pages 2643-2649

Minireview: Implication of mitochondria in insulin secretion and action

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; DNA POLYMERASE; FATTY ACID; GLUCOSE; INSULIN; TRANSCRIPTION FACTOR; UNCOUPLING PROTEIN 2;

EID: 33646779855     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0057     Document Type: Short Survey
Times cited : (172)

References (72)
  • 1
    • 0036865991 scopus 로고    scopus 로고
    • Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic β-cells
    • Maechler P 2002 Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic β-cells. Cell Mol Life Sci 59:1803-1818
    • (2002) Cell Mol Life Sci , vol.59 , pp. 1803-1818
    • Maechler, P.1
  • 2
    • 4043086952 scopus 로고    scopus 로고
    • Mitochondria in health and disease: Perspectives on a new mitochondrial biology
    • Duchen MR 2004 Mitochondria in health and disease: perspectives on a new mitochondrial biology. Mol Aspects Med 25:365-451
    • (2004) Mol Aspects Med , vol.25 , pp. 365-451
    • Duchen, M.R.1
  • 3
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • Lowell BB, Shulman GI 2005 Mitochondrial dysfunction and type 2 diabetes. Science 307:384-387
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 4
    • 0036311080 scopus 로고    scopus 로고
    • β-Cell mitochondria and insulin secretion: Messenger role of nucleotides and metabolites
    • Wollheim CB, Maechler P 2002 β-Cell mitochondria and insulin secretion: messenger role of nucleotides and metabolites. Diabetes 51(Suppl 1):S37-S42
    • (2002) Diabetes , vol.51 , Issue.1 SUPPL.
    • Wollheim, C.B.1    Maechler, P.2
  • 5
    • 9444259786 scopus 로고    scopus 로고
    • Pathways in β-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues
    • Henquin JC 2004 Pathways in β-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues. Diabetes 53(Suppl 3):S48-S58
    • (2004) Diabetes , vol.53 , Issue.3 SUPPL.
    • Henquin, J.C.1
  • 6
    • 33644872401 scopus 로고    scopus 로고
    • In β-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion
    • Maechler P, Carobbio S, Rubi B 2006 In β-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion. Int J Biochem Cell Biol 38(5-6):696-709
    • (2006) Int J Biochem Cell Biol , vol.38 , Issue.5-6 , pp. 696-709
    • Maechler, P.1    Carobbio, S.2    Rubi, B.3
  • 7
    • 0036896635 scopus 로고    scopus 로고
    • Regulation of pancreatic β-cell glucokinase: From basics to therapeutics
    • Matschinsky FM 2002 Regulation of pancreatic β-cell glucokinase: from basics to therapeutics. Diabetes 51(Suppl 3):S394-S404
    • (2002) Diabetes , vol.51 , Issue.3 SUPPL.
    • Matschinsky, F.M.1
  • 9
    • 0030810982 scopus 로고    scopus 로고
    • Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in β cells
    • Schuit F, De Vos A, Farfari S, Moens K, Pipeleers D, Brun T, Prentki M 1997 Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in β cells. J Biol Chem 272:18572-18579
    • (1997) J Biol Chem , vol.272 , pp. 18572-18579
    • Schuit, F.1    De Vos, A.2    Farfari, S.3    Moens, K.4    Pipeleers, D.5    Brun, T.6    Prentki, M.7
  • 12
    • 27144525581 scopus 로고    scopus 로고
    • New mitochondrial carriers: An overview
    • Arco AD, Satrustegui J 2005 New mitochondrial carriers: an overview. Cell Mol Life Sci 62:2204-2227
    • (2005) Cell Mol Life Sci , vol.62 , pp. 2204-2227
    • Arco, A.D.1    Satrustegui, J.2
  • 13
    • 11244318158 scopus 로고    scopus 로고
    • The malate-aspartate NADH shuttle member aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in β cells
    • Rubi B, del Arco A, Bartley C, Satrustegui J, Maechler P 2004 The malate-aspartate NADH shuttle member aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in β cells. J Biol Chem 279:55659-55666
    • (2004) J Biol Chem , vol.279 , pp. 55659-55666
    • Rubi, B.1    Del Arco, A.2    Bartley, C.3    Satrustegui, J.4    Maechler, P.5
  • 14
    • 0036829678 scopus 로고    scopus 로고
    • Switch to anaerobic glucose metabolism with NADH accumulation in the β-cell model of mitochondrial diabetes. Characteristics of βHC9 cells deficient in mitochondrial DNA transcription
    • Noda M, Yamashita S, Takahashi N, Eto K, Shen LM, Izumi K, Daniel S, Tsubamoto Y, Nemoto T, Iino M, Kasai H, Sharp GW, Kadowaki T 2002 Switch to anaerobic glucose metabolism with NADH accumulation in the β-cell model of mitochondrial diabetes. Characteristics of βHC9 cells deficient in mitochondrial DNA transcription. J Biol Chem 277:41817-41826
    • (2002) J Biol Chem , vol.277 , pp. 41817-41826
    • Noda, M.1    Yamashita, S.2    Takahashi, N.3    Eto, K.4    Shen, L.M.5    Izumi, K.6    Daniel, S.7    Tsubamoto, Y.8    Nemoto, T.9    Iino, M.10    Kasai, H.11    Sharp, G.W.12    Kadowaki, T.13
  • 16
    • 0031892856 scopus 로고    scopus 로고
    • Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells
    • Kennedy ED, Maechler P, Wollheim CB 1998 Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells. Diabetes 47:374-380
    • (1998) Diabetes , vol.47 , pp. 374-380
    • Kennedy, E.D.1    Maechler, P.2    Wollheim, C.B.3
  • 18
    • 0037023692 scopus 로고    scopus 로고
    • Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic β cell: A survey of four fuel secretagogues
    • Antinozzi PA, Ishihara H, Newgard CB, Wollheim CB 2002 Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic β cell: a survey of four fuel secretagogues. J Biol Chem 277:11746-11755
    • (2002) J Biol Chem , vol.277 , pp. 11746-11755
    • Antinozzi, P.A.1    Ishihara, H.2    Newgard, C.B.3    Wollheim, C.B.4
  • 20
    • 0042879951 scopus 로고    scopus 로고
    • Insulin granule dynamics in pancreatic β cells
    • Rorsman P, Renstrom E 2003 Insulin granule dynamics in pancreatic β cells. Diabetologia 46:1029-1045
    • (2003) Diabetologia , vol.46 , pp. 1029-1045
    • Rorsman, P.1    Renstrom, E.2
  • 23
    • 0034064334 scopus 로고    scopus 로고
    • β-Cell mitochondria in the regulation of insulin secretion: A new culprit in type II diabetes
    • Wollheim CB 2000 β-Cell mitochondria in the regulation of insulin secretion: a new culprit in type II diabetes. Diabetologia 43:265-277
    • (2000) Diabetologia , vol.43 , pp. 265-277
    • Wollheim, C.B.1
  • 27
    • 0026632641 scopus 로고
    • Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells
    • Gembal M, Gilon P, Henquin JC 1992 Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells. J Clin Invest 89:1288-1295
    • (1992) J Clin Invest , vol.89 , pp. 1288-1295
    • Gembal, M.1    Gilon, P.2    Henquin, J.C.3
  • 28
    • 0030926003 scopus 로고    scopus 로고
    • Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic β-cells
    • Maechler P, Kennedy ED, Pozzan T, Wollheim CB 1997 Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic β-cells. EMBO J 16:3833-3841
    • (1997) EMBO J , vol.16 , pp. 3833-3841
    • Maechler, P.1    Kennedy, E.D.2    Pozzan, T.3    Wollheim, C.B.4
  • 29
    • 0033540037 scopus 로고    scopus 로고
    • Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis
    • Maechler P, Wollheim CB 1999 Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. Nature 402:685-689
    • (1999) Nature , vol.402 , pp. 685-689
    • Maechler, P.1    Wollheim, C.B.2
  • 30
    • 0034072556 scopus 로고    scopus 로고
    • Glucose-regulated anaplerosis and cataplerosis in pancreatic β-cells: Possible implication of a pyruvate/ citrate shuttle in insulin secretion
    • Farfari S, Schulz V, Corkey B, Prentki M 2000 Glucose-regulated anaplerosis and cataplerosis in pancreatic β-cells: possible implication of a pyruvate/ citrate shuttle in insulin secretion. Diabetes 49:718-726
    • (2000) Diabetes , vol.49 , pp. 718-726
    • Farfari, S.1    Schulz, V.2    Corkey, B.3    Prentki, M.4
  • 32
    • 0034737731 scopus 로고    scopus 로고
    • Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI β-cells)
    • Deeney JT, Gromada J, Hoy M, Olsen HL, Rhodes CJ, Prentki M, Berggren PO, Corkey BE 2000 Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI β-cells). J Biol Chem 275:9363-9368
    • (2000) J Biol Chem , vol.275 , pp. 9363-9368
    • Deeney, J.T.1    Gromada, J.2    Hoy, M.3    Olsen, H.L.4    Rhodes, C.J.5    Prentki, M.6    Berggren, P.O.7    Corkey, B.E.8
  • 36
    • 0037031896 scopus 로고    scopus 로고
    • The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related
    • Bertrand G, Ishiyama N, Nenquin M, Ravier MA, Henquin JC 2002 The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related. J Biol Chem 277:32883-32891
    • (2002) J Biol Chem , vol.277 , pp. 32883-32891
    • Bertrand, G.1    Ishiyama, N.2    Nenquin, M.3    Ravier, M.A.4    Henquin, J.C.5
  • 37
    • 0038540613 scopus 로고    scopus 로고
    • Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion
    • Broca C, Brennan L, Petit P, Newsholme P, Maechler P 2003 Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion. FEBS Lett 545:167-172
    • (2003) FEBS Lett , vol.545 , pp. 167-172
    • Broca, C.1    Brennan, L.2    Petit, P.3    Newsholme, P.4    Maechler, P.5
  • 39
    • 0036894314 scopus 로고    scopus 로고
    • Glutaminolysis and insulin secretion: From bedside to bench and back
    • Kelly A, Li C, Gao Z, Stanley CA, Matschinsky FM 2002 Glutaminolysis and insulin secretion: from bedside to bench and back. Diabetes 51(Suppl 3):S421-S426
    • (2002) Diabetes , vol.51 , Issue.3 SUPPL.
    • Kelly, A.1    Li, C.2    Gao, Z.3    Stanley, C.A.4    Matschinsky, F.M.5
  • 40
    • 0035856942 scopus 로고    scopus 로고
    • Mitochondrial function in normal and diabetic β-cells
    • Maechler P, Wollheim CB 2001 Mitochondrial function in normal and diabetic β-cells. Nature 414:807-812
    • (2001) Nature , vol.414 , pp. 807-812
    • Maechler, P.1    Wollheim, C.B.2
  • 41
    • 20344378241 scopus 로고    scopus 로고
    • Molecular mechanisms of mitochondrial diabetes (MIDD)
    • Maassen JA, Janssen GM, t Hart LM 2005 Molecular mechanisms of mitochondrial diabetes (MIDD). Ann Med 37:213-221
    • (2005) Ann Med , vol.37 , pp. 213-221
    • Maassen, J.A.1    Janssen, G.M.2    T Hart, L.M.3
  • 42
    • 0030747209 scopus 로고    scopus 로고
    • In situ characterization of islets in diabetes with a mitochondrial DNA mutation at nucleotide position 3243
    • Kobayashi T, Nakanishi K, Nakase H, Kajio H, Okubo M, Murase T, Kosaka K 1997 In situ characterization of islets in diabetes with a mitochondrial DNA mutation at nucleotide position 3243. Diabetes 46:1567-1571
    • (1997) Diabetes , vol.46 , pp. 1567-1571
    • Kobayashi, T.1    Nakanishi, K.2    Nakase, H.3    Kajio, H.4    Okubo, M.5    Murase, T.6    Kosaka, K.7
  • 43
    • 9444242665 scopus 로고    scopus 로고
    • Five stages of evolving β-cell dysfunction during progression to diabetes
    • Weir GC, Bonner-Weir S 2004 Five stages of evolving β-cell dysfunction during progression to diabetes. Diabetes 53(Suppl 3):S16-S21
    • (2004) Diabetes , vol.53 , Issue.3 SUPPL.
    • Weir, G.C.1    Bonner-Weir, S.2
  • 44
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban RS, Nemoto S, Finkel T 2005 Mitochondria, oxidants, and aging. Cell 120:483-495
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 46
    • 0033595684 scopus 로고    scopus 로고
    • Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication
    • Michikawa Y, Mazzucchelli F, Bresolin N, Scarlato G, Attardi G 1999 Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication. Science 286:774-779
    • (1999) Science , vol.286 , pp. 774-779
    • Michikawa, Y.1    Mazzucchelli, F.2    Bresolin, N.3    Scarlato, G.4    Attardi, G.5
  • 50
    • 20144364947 scopus 로고    scopus 로고
    • Glucose suppresses superoxide generation in metabolically responsive pancreatic β cells
    • Martens GA, Cai Y, Hinke S, Stange G, Van de Casteele M, Pipeleers D 2005 Glucose suppresses superoxide generation in metabolically responsive pancreatic β cells. J Biol Chem 280:20389-20396
    • (2005) J Biol Chem , vol.280 , pp. 20389-20396
    • Martens, G.A.1    Cai, Y.2    Hinke, S.3    Stange, G.4    Van De Casteele, M.5    Pipeleers, D.6
  • 51
    • 0030689041 scopus 로고    scopus 로고
    • Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells
    • Tiedge M, Lortz S, Drinkgern J, Lenzen S 1997 Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells. Diabetes 46:1733-1742
    • (1997) Diabetes , vol.46 , pp. 1733-1742
    • Tiedge, M.1    Lortz, S.2    Drinkgern, J.3    Lenzen, S.4
  • 52
    • 10044219818 scopus 로고    scopus 로고
    • Five cysteine-containing compounds delay diabetic deterioration in BALB/cA mice
    • Hsu CC, Yen HF, Yin MC, Tsai CM, Hsieh CH 2004 Five cysteine-containing compounds delay diabetic deterioration in BALB/cA mice. J Nutr 134:3245-3249
    • (2004) J Nutr , vol.134 , pp. 3245-3249
    • Hsu, C.C.1    Yen, H.F.2    Yin, M.C.3    Tsai, C.M.4    Hsieh, C.H.5
  • 57
    • 33644868208 scopus 로고    scopus 로고
    • Uncoupling protein 2 overexpression prevents cytokine-induced reactive oxygen species production and apoptosis in pancreatic β cells
    • Zengaffinen N, Perreten H, Lameloise N, Keller P, Muzzin P, Assimacopoulos-Jeannet F 2005 Uncoupling protein 2 overexpression prevents cytokine-induced reactive oxygen species production and apoptosis in pancreatic β cells. Diabetologia 48:A38
    • (2005) Diabetologia , vol.48
    • Zengaffinen, N.1    Perreten, H.2    Lameloise, N.3    Keller, P.4    Muzzin, P.5    Assimacopoulos-Jeannet, F.6
  • 59
  • 60
    • 3843101644 scopus 로고    scopus 로고
    • Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets
    • Gauthier BR, Brun T, Sarret EJ, Ishihara H, Schaad O, Descombes P, Wollheim CB 2004 Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets. J Biol Chem 279:31121-31130
    • (2004) J Biol Chem , vol.279 , pp. 31121-31130
    • Gauthier, B.R.1    Brun, T.2    Sarret, E.J.3    Ishihara, H.4    Schaad, O.5    Descombes, P.6    Wollheim, C.B.7
  • 62
    • 33645982255 scopus 로고    scopus 로고
    • From mice to men: Insights into the insulin resistance syndromes
    • Biddinger SB, Kahn CR 2005 From mice to men: insights into the insulin resistance syndromes. Annu Rev Physiol 68:123-158
    • (2005) Annu Rev Physiol , vol.68 , pp. 123-158
    • Biddinger, S.B.1    Kahn, C.R.2
  • 63
    • 2542593338 scopus 로고    scopus 로고
    • Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes
    • Schrauwen P, Hesselink MK 2004 Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes. Diabetes 53:1412-1417
    • (2004) Diabetes , vol.53 , pp. 1412-1417
    • Schrauwen, P.1    Hesselink, M.K.2
  • 64
    • 1642367438 scopus 로고    scopus 로고
    • Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes
    • Storgaard H, Jensen CB, Bjornholm M, Song XM, Madsbad S, Zierath JR, Vaag AA 2004 Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes. J Clin Endocrinol Metab 89:1301-1311
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1301-1311
    • Storgaard, H.1    Jensen, C.B.2    Bjornholm, M.3    Song, X.M.4    Madsbad, S.5    Zierath, J.R.6    Vaag, A.A.7
  • 66
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI 2004 Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 350:664-671
    • (2004) N Engl J Med , vol.350 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 67
    • 0038271638 scopus 로고    scopus 로고
    • Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts
    • USA
    • Stump CS, Short KR, Bigelow ML, Schimke JM, Nair KS 2003 Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts. Proc Natl Acad Sci USA 100:7996-8001
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 7996-8001
    • Stump, C.S.1    Short, K.R.2    Bigelow, M.L.3    Schimke, J.M.4    Nair, K.S.5
  • 68
    • 3843061592 scopus 로고    scopus 로고
    • AMP kinase and malonyl-CoA: Targets for therapy of the metabolic syndrome
    • Ruderman N, Prentki M 2004 AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome. Nat Rev Drug Discov 3:340-351
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 340-351
    • Ruderman, N.1    Prentki, M.2
  • 72
    • 28844433549 scopus 로고    scopus 로고
    • A role for hypothalamic malonyl-CoA in the control of food intake
    • Hu Z, Dai Y, Prentki M, Chohnan S, Lane MD 2005 A role for hypothalamic malonyl-CoA in the control of food intake. J Biol Chem 280:39681-39683
    • (2005) J Biol Chem , vol.280 , pp. 39681-39683
    • Hu, Z.1    Dai, Y.2    Prentki, M.3    Chohnan, S.4    Lane, M.D.5


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