Dissociation between fat-induced in Vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 3, 2004, Pages 1301-1311

  Storgaard, Heidi ^a,c   Jensen, Christine B ^a   Björnholm, Marie ^b   Song, Xiao Mei ^b   Madsbad, Sten ^a   Zierath, Juleen R ^b   Vaag, Allan A ^a,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c STENO DIABETES CENTER   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; INSULIN RECEPTOR; INTRALIPID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TYROSINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC OBESITY; DIFFERENTIAL SCANNING CALORIMETRY; DISSOCIATION; ENZYME ACTIVITY; GLUCOSE CLAMP TECHNIQUE; GLUCOSE HOMEOSTASIS; GLUCOSE INFUSION; GLUCOSE INTOLERANCE; GLUCOSE OXIDATION; HUMAN; HUMAN TISSUE; HYPERINSULINEMIA; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SYNTHESIS; INTERMETHOD COMPARISON; LIPID PEROXIDATION; LONG TERM EXPOSURE; MALE; MECHANOTRANSDUCTION; METABOLIC ACTIVATION; MUSCLE BIOPSY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RISK FACTOR; VASTUS LATERALIS MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOOD GLUCOSE; C-PEPTIDE; CALORIMETRY, INDIRECT; DIABETES MELLITUS, TYPE 2; FAT EMULSIONS, INTRAVENOUS; FATTY ACIDS, NONESTERIFIED; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; INSULIN RESISTANCE; MIDDLE AGED; MUSCLE, SKELETAL; OXIDATION-REDUCTION; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RISK FACTORS; SIGNAL TRANSDUCTION; TRIGLYCERIDES;

EID: 1642367438     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-031243     Document Type: Article

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