메뉴 건너뛰기




Volumn 52, Issue 3, 2006, Pages 856-884

Role of mathematical modeling on the optimal control of HIV-1 pathogenesis

Author keywords

AIDS pathogenesis; Chemotherapy; HAART; HIV 1; Mathematical modeling

Indexed keywords

ACQUIRED IMMUNO DEFICIENCY SYNDROME (AIDS); AIDS PATHOGENESIS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART); HUMAN IMMUNODEFICIENCY VIRUS (HIV);

EID: 33645579942     PISSN: 00011541     EISSN: 15475905     Source Type: Journal    
DOI: 10.1002/aic.10716     Document Type: Review
Times cited : (39)

References (187)
  • 1
    • 0034048013 scopus 로고    scopus 로고
    • Early HIV infection in vivo: Branching-process model for studying timing of immune responses and drug therapy
    • Wick D, Self SG. Early HIV infection in vivo: branching-process model for studying timing of immune responses and drug therapy. Math Biosci. 2000;165:115-134.
    • (2000) Math Biosci. , vol.165 , pp. 115-134
    • Wick, D.1    Self, S.G.2
  • 2
    • 0030095028 scopus 로고    scopus 로고
    • A model for treatment strategy in the chemotherapy of AIDS
    • Kirschner D, Webb GF. A model for treatment strategy in the chemotherapy of AIDS. Bull Math Biol. 1996;58(2):367-390.
    • (1996) Bull Math Biol. , vol.58 , Issue.2 , pp. 367-390
    • Kirschner, D.1    Webb, G.F.2
  • 3
    • 0031204179 scopus 로고    scopus 로고
    • Optimal control of the chemotherapy of HIV
    • Kirschner D, Lenhart S, Serbin S. Optimal control of the chemotherapy of HIV. J Math Biol. 1997;35:775-792.
    • (1997) J Math Biol. , vol.35 , pp. 775-792
    • Kirschner, D.1    Lenhart, S.2    Serbin, S.3
  • 4
    • 0031557385 scopus 로고    scopus 로고
    • Dynamic multidrug therapies for HIV: A control theoretic approach
    • Wein LM, Zenios SA, Nowak MA. Dynamic multidrug therapies for HIV: A control theoretic approach. J Theor Biol. 1997;185:15-29.
    • (1997) J Theor Biol. , vol.185 , pp. 15-29
    • Wein, L.M.1    Zenios, S.A.2    Nowak, M.A.3
  • 5
    • 0033431041 scopus 로고    scopus 로고
    • Specific therapy regimes could lead to long-term immunological control of HIV
    • Wodarz D, Nowak MA. Specific therapy regimes could lead to long-term immunological control of HIV. PNAS-USA. 1999;96(25): 14464-14469.
    • (1999) PNAS-USA , vol.96 , Issue.25 , pp. 14464-14469
    • Wodarz, D.1    Nowak, M.A.2
  • 6
    • 33645559275 scopus 로고    scopus 로고
    • Technical Report - Department of Pathology, University of Utah
    • Klatt EC. Pathology of AIDS. Technical Report - Department of Pathology, University of Utah; 2000.
    • (2000) Pathology of AIDS
    • Klatt, E.C.1
  • 10
    • 0011192817 scopus 로고
    • A model for the immune system response to HIV: AZT Treatment Studies
    • Theory of Epidemics, Arino O, Axelrod D, Kimmel M. eds. Winnipeg, Manitoba, Canada: Wuerz Publishing
    • Kirschner D, Perelson A. A model for the immune system response to HIV: AZT Treatment Studies. In: Mathematical Population Dynamics III. Theory of Epidemics, Arino O, Axelrod D, Kimmel M. eds. Winnipeg, Manitoba, Canada: Wuerz Publishing; 1994:(1)296-301.
    • (1994) Mathematical Population Dynamics III , Issue.1 , pp. 296-301
    • Kirschner, D.1    Perelson, A.2
  • 11
    • 0031729823 scopus 로고    scopus 로고
    • Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
    • Kilby JM, Hopkins S, Venetta TM. Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat Med. 1998;4:1302-1307.
    • (1998) Nat Med. , vol.4 , pp. 1302-1307
    • Kilby, J.M.1    Hopkins, S.2    Venetta, T.M.3
  • 12
    • 77956719426 scopus 로고
    • Current Clinical Treatment of Retroviral Infections
    • Ed.: Jeffries DJ, De Clercq E, Chichester, UK: John Wiley & Sons;
    • Bowen EF, Atkins M, Weller IVD, Johnson MA. Current Clinical Treatment of Retroviral Infections. In: Antiviral Chemotherapy, Ed.: Jeffries DJ, De Clercq E, Chichester, UK: John Wiley & Sons; 1995:65-79.
    • (1995) Antiviral Chemotherapy , pp. 65-79
    • Bowen, E.F.1    Atkins, M.2    Weller, I.V.D.3    Johnson, M.A.4
  • 13
    • 0029927979 scopus 로고    scopus 로고
    • Saquinavir/zidovudine combination in patients with advanced HIV infection and no prior antiretroviral therapy: CD4+ Lymphocyte/plasma RNA changes, and emergence of HIV strains with reduced phenotypic sensitivity
    • Vella S, Galluzzo C, Giannini G, Pirillo MF, Duncan I, Jacobsen H, Andreoni M, Sarmati L, Ercoli L. Saquinavir/zidovudine combination in patients with advanced HIV infection and no prior antiretroviral therapy: CD4+ Lymphocyte/plasma RNA changes, and emergence of HIV strains with reduced phenotypic sensitivity. Antiviral Res. 1996;29:91-93.
    • (1996) Antiviral Res. , vol.29 , pp. 91-93
    • Vella, S.1    Galluzzo, C.2    Giannini, G.3    Pirillo, M.F.4    Duncan, I.5    Jacobsen, H.6    Andreoni, M.7    Sarmati, L.8    Ercoli, L.9
  • 14
    • 2642670612 scopus 로고    scopus 로고
    • Human immunodeficiency viruses and human T-lymphotropic viruses
    • Eds. Galasso GJ, Whitley RJ, Merigan TC. Philadelphia: Lippincott-Raven Publishers
    • Boucher CAB. Human Immunodeficiency Viruses and Human T-Lymphotropic Viruses. In: Antiviral Agents and Human Viral Diseases. 4th ed. Eds. Galasso GJ, Whitley RJ, Merigan TC. Philadelphia: Lippincott-Raven Publishers; 1997:607-695.
    • (1997) Antiviral Agents and Human Viral Diseases. 4th Ed. , pp. 607-695
    • Boucher, C.A.B.1
  • 18
    • 0030589546 scopus 로고    scopus 로고
    • Preliminary in vitro growth cycle and transmission studies of HIV-1 in an autologous primary cell assay of blood-derived macrophages and peripheral blood mononuclear cells
    • Tsai WP, Conley SR, Kung HF, Garrity RR, Nara PL. Preliminary in vitro growth cycle and transmission studies of HIV-1 in an autologous primary cell assay of blood-derived macrophages and peripheral blood mononuclear cells. Virology. 1996;226:205-216.
    • (1996) Virology , vol.226 , pp. 205-216
    • Tsai, W.P.1    Conley, S.R.2    Kung, H.F.3    Garrity, R.R.4    Nara, P.L.5
  • 19
    • 0031575431 scopus 로고    scopus 로고
    • Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
    • Connor RI, Sheridan KE, Ceradini D, Choe S, Landau NR. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J Exp Med. 1997;185(4):621-628.
    • (1997) J Exp Med. , vol.185 , Issue.4 , pp. 621-628
    • Connor, R.I.1    Sheridan, K.E.2    Ceradini, D.3    Choe, S.4    Landau, N.R.5
  • 23
    • 0032837825 scopus 로고    scopus 로고
    • Role of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus Type 1 (HIV-1) strains: Two distinct mechanisms of HIV-1 dual tropism
    • Yi Y, Isaacs SN, Williams DA, Frank I, Schols D, De Clercq E, Kolson DL, Collman RG. Role of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus Type 1 (HIV-1) strains: two distinct mechanisms of HIV-1 dual tropism. J Virol. 1999;73(9):7117-7125.
    • (1999) J Virol. , vol.73 , Issue.9 , pp. 7117-7125
    • Yi, Y.1    Isaacs, S.N.2    Williams, D.A.3    Frank, I.4    Schols, D.5    De Clercq, E.6    Kolson, D.L.7    Collman, R.G.8
  • 24
    • 0034466833 scopus 로고    scopus 로고
    • Evolution of the human immunodeficiency virus type 1 envelope during infection reveals molecular corollaries of specificity for coreceptor utilization and AIDS pathogenesis
    • Hu Q, Barry AP, Wang Z, Connolly SM, Peiper SC, Greenberg ML. Evolution of the human immunodeficiency virus type 1 envelope during infection reveals molecular corollaries of specificity for coreceptor utilization and AIDS pathogenesis. J Virol. 2000;74(24):11858-11872.
    • (2000) J Virol. , vol.74 , Issue.24 , pp. 11858-11872
    • Hu, Q.1    Barry, A.P.2    Wang, Z.3    Connolly, S.M.4    Peiper, S.C.5    Greenberg, M.L.6
  • 26
    • 0033837856 scopus 로고    scopus 로고
    • Influence of nucleotide polymorphisms in the CCR2 gene and the CCR5 promoter on the expression of cell surface CCR5 and CXCR4
    • Shieh B, Liau Y, Hsieh P, Yan Y, Wang S, Li C. Influence of nucleotide polymorphisms in the CCR2 gene and the CCR5 promoter on the expression of cell surface CCR5 and CXCR4. Intl Immunol. 2000;12(9):1311-1318.
    • (2000) Intl Immunol. , vol.12 , Issue.9 , pp. 1311-1318
    • Shieh, B.1    Liau, Y.2    Hsieh, P.3    Yan, Y.4    Wang, S.5    Li, C.6
  • 28
    • 0030256247 scopus 로고    scopus 로고
    • A mathematical model and CD4 lymphocyte dynamics in HIV infection
    • Hraba T, Dolezal J. A mathematical model and CD4 lymphocyte dynamics in HIV infection. Emerging Infectious Diseases. 1996;2(4): 299-305.
    • (1996) Emerging Infectious Diseases , vol.2 , Issue.4 , pp. 299-305
    • Hraba, T.1    Dolezal, J.2
  • 29
    • 0025226583 scopus 로고
    • A model of human immunodeficiency virus infection in T helper cell clones
    • McLean AR, Kirkwood TBL. A model of human immunodeficiency virus infection in T helper cell clones. J Theor Biol 1990;147:177-203.
    • (1990) J Theor Biol , vol.147 , pp. 177-203
    • McLean, A.R.1    Kirkwood, T.B.L.2
  • 30
    • 0026574212 scopus 로고
    • Models of interactions between HIV and other pathogens
    • McLean AR, Nowak MA. Models of interactions between HIV and other pathogens. J Theor Biol. 1992;155:69-102.
    • (1992) J Theor Biol. , vol.155 , pp. 69-102
    • McLean, A.R.1    Nowak, M.A.2
  • 31
    • 0028116794 scopus 로고
    • Modeling HIV infection of CD4+ T-cell subpopulations
    • Essunger P, Perelson AS. Modeling HIV infection of CD4+ T-cell subpopulations. J Theor Biol. 1994;170:367-391.
    • (1994) J Theor Biol. , vol.170 , pp. 367-391
    • Essunger, P.1    Perelson, A.S.2
  • 33
  • 35
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 Dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    • Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD. HIV-1 Dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time. Science. 1996;271(15):1582-1586.
    • (1996) Science , vol.271 , Issue.15 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 36
    • 0031581661 scopus 로고    scopus 로고
    • Anti-viral drug treatment: Dynamics of resistance in free virus and infected cell populations
    • Nowak MA, Bonhoeffer S, Shaw GM, May RM. Anti-viral drug treatment: Dynamics of resistance in free virus and infected cell populations. J Theor Biosci. 1997;184:203-217.
    • (1997) J Theor Biosci. , vol.184 , pp. 203-217
    • Nowak, M.A.1    Bonhoeffer, S.2    Shaw, G.M.3    May, R.M.4
  • 37
    • 0031558224 scopus 로고    scopus 로고
    • The necessity of cofactors in the pathogenesis of AIDS: A mathematical model
    • Root-Bernstein RS, Merrill SJ. The necessity of cofactors in the pathogenesis of AIDS: A mathematical model. J Theor Biol. 1997; 187:135-146.
    • (1997) J Theor Biol. , vol.187 , pp. 135-146
    • Root-Bernstein, R.S.1    Merrill, S.J.2
  • 38
    • 0031060375 scopus 로고    scopus 로고
    • Clinical data sets of human immunodeficiency virus type 1 reverse transcriptase-resistant mutants explained by a mathematical model
    • Stilianakis NI, Boucher CAB, Jong MD, Leeuwen RV, Schuurman R, Boer RJ. Clinical data sets of human immunodeficiency virus type 1 reverse transcriptase-resistant mutants explained by a mathematical model. J Virol. 1997a;71(1):161-168.
    • (1997) J Virol. , vol.71 , Issue.1 , pp. 161-168
    • Stilianakis, N.I.1    Boucher, C.A.B.2    Jong, M.D.3    Leeuwen, R.V.4    Schuurman, R.5    Boer, R.J.6
  • 39
    • 0030772639 scopus 로고    scopus 로고
    • Analysis of a model for the pathogenesis of AIDS
    • Stilianakis NI, Dietz K, Schenzle D. Analysis of a model for the pathogenesis of AIDS. Math Biosci. 1997b;145:27-46.
    • (1997) Math Biosci. , vol.145 , pp. 27-46
    • Stilianakis, N.I.1    Dietz, K.2    Schenzle, D.3
  • 40
    • 0032492107 scopus 로고    scopus 로고
    • Target cell limited and immune control models of HIV infection: A comparison
    • De Boer RJ, Perelson AS. Target cell limited and immune control models of HIV infection: A comparison. J Theor Biol. 1998;190:201-214.
    • (1998) J Theor Biol. , vol.190 , pp. 201-214
    • De Boer, R.J.1    Perelson, A.S.2
  • 41
    • 0032168279 scopus 로고    scopus 로고
    • Influence of delayed viral production on viral dynamics in HIV-1 infected patients
    • Mittler JE, Sulzer B, Neumann AU, Perelson AS. Influence of delayed viral production on viral dynamics in HIV-1 infected patients. Math Biosci. 1998;152:143-163.
    • (1998) Math Biosci. , vol.152 , pp. 143-163
    • Mittler, J.E.1    Sulzer, B.2    Neumann, A.U.3    Perelson, A.S.4
  • 44
    • 0032518729 scopus 로고    scopus 로고
    • Stochastic modeling of the dynamics of CD4+ T-cell infection by HIV and some Monte Carlo studies
    • Tan WY, Wu H. Stochastic modeling of the dynamics of CD4+ T-cell infection by HIV and some Monte Carlo studies. Math Biosci. 1998;147:173-205.
    • (1998) Math Biosci. , vol.147 , pp. 173-205
    • Tan, W.Y.1    Wu, H.2
  • 45
    • 0032492830 scopus 로고    scopus 로고
    • Mathematical analysis of antiretroviral therapy aimed at HIV-1 eradication or maintenance of low viral loads
    • Wein LM, D'Amato RM, Perelson AS. Mathematical analysis of antiretroviral therapy aimed at HIV-1 eradication or maintenance of low viral loads. J Theor Biol. 1998;192:81-98.
    • (1998) J Theor Biol. , vol.192 , pp. 81-98
    • Wein, L.M.1    D'Amato, R.M.2    Perelson, A.S.3
  • 46
    • 0032864856 scopus 로고    scopus 로고
    • Relationships between antiviral treatment effects and biphasic viral decay rates in modeling HIV dynamics
    • Ding AA, Wu H. Relationships between antiviral treatment effects and biphasic viral decay rates in modeling HIV dynamics. Math Biosci. 1999;160:63-82.
    • (1999) Math Biosci. , vol.160 , pp. 63-82
    • Ding, A.A.1    Wu, H.2
  • 47
    • 0001918317 scopus 로고    scopus 로고
    • Mathematical analysis of HIV-1 dynamics in vivo
    • Perelson AS, Nelson PW. Mathematical analysis of HIV-1 dynamics in vivo. SIAM Review. 1999;41(1):3-44.
    • (1999) SIAM Review , vol.41 , Issue.1 , pp. 3-44
    • Perelson, A.S.1    Nelson, P.W.2
  • 48
    • 0032896058 scopus 로고    scopus 로고
    • Some state space models of HIV pathogenesis under treatment by anti-viral drugs in HIV-infected individuals
    • Tan WY, Xiang Z. Some state space models of HIV pathogenesis under treatment by anti-viral drugs in HIV-infected individuals. Math Biosci. 1999;156:69-94.
    • (1999) Math Biosci. , vol.156 , pp. 69-94
    • Tan, W.Y.1    Xiang, Z.2
  • 50
    • 0034005931 scopus 로고    scopus 로고
    • A model of HIV-1 pathogenesis that includes an intracellular delay
    • Nelson PW, Murray JD, Perelson AS. A model of HIV-1 pathogenesis that includes an intracellular delay. Math Biosci. 2000;163:201-215.
    • (2000) Math Biosci. , vol.163 , pp. 201-215
    • Nelson, P.W.1    Murray, J.D.2    Perelson, A.S.3
  • 52
    • 0035052008 scopus 로고    scopus 로고
    • A stochastic modeling of early HIV-1 population dynamics
    • Kamina A, Makuch RW, Zhao H. A stochastic modeling of early HIV-1 population dynamics. Math Biosci. 2001;170:187-198.
    • (2001) Math Biosci. , vol.170 , pp. 187-198
    • Kamina, A.1    Makuch, R.W.2    Zhao, H.3
  • 53
    • 0003787146 scopus 로고
    • Princeton: Princeton University Press
    • Bellman R. Dynamic Programming. Princeton: Princeton University Press; 1957.
    • (1957) Dynamic Programming
    • Bellman, R.1
  • 57
  • 59
    • 0037440551 scopus 로고    scopus 로고
    • An efficient multiple shooting based reduced SQP strategy for large-scale dynamic process optimization
    • Leineweber DB, Schafer A, Bock HG, Schloder JP. An efficient multiple shooting based reduced SQP strategy for large-scale dynamic process optimization. Comp Chem Eng. 2003;27(2):167-174.
    • (2003) Comp Chem Eng. , vol.27 , Issue.2 , pp. 167-174
    • Leineweber, D.B.1    Schafer, A.2    Bock, H.G.3    Schloder, J.P.4
  • 60
    • 0031472588 scopus 로고    scopus 로고
    • Role of pharmacokinetics and metabolism in drug discovery and development
    • Lin JH, Lu AYH. Role of pharmacokinetics and metabolism in drug discovery and development. Pharmacol Rev. 1997;49(4):403-449.
    • (1997) Pharmacol Rev. , vol.49 , Issue.4 , pp. 403-449
    • Lin, J.H.1    Lu, A.Y.H.2
  • 61
    • 0034065983 scopus 로고    scopus 로고
    • Pharmacologic characteristics of indinavir, didanosine, and stavudine in human immunodeficiency virus-infected children receiving combination therapy
    • Fletcher CV, Brundage RC, Remmel RP, Page LM, Weller D, Calles NR, Simon C, Kline MW. Pharmacologic characteristics of indinavir, didanosine, and stavudine in human immunodeficiency virus-infected children receiving combination therapy. Antimicrob Agents Chemother. 2000;44(4):1029-1034.
    • (2000) Antimicrob Agents Chemother , vol.44 , Issue.4 , pp. 1029-1034
    • Fletcher, C.V.1    Brundage, R.C.2    Remmel, R.P.3    Page, L.M.4    Weller, D.5    Calles, N.R.6    Simon, C.7    Kline, M.W.8
  • 62
    • 0031042433 scopus 로고    scopus 로고
    • The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
    • Bleul CC, Wu L, Hoxie JA, Springer TA, Mackay CR. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. PNAS USA. 1997;94:1925-1930.
    • (1997) PNAS USA , vol.94 , pp. 1925-1930
    • Bleul, C.C.1    Wu, L.2    Hoxie, J.A.3    Springer, T.A.4    Mackay, C.R.5
  • 64
    • 0030881697 scopus 로고    scopus 로고
    • Lysis of HIV-1 infected cells and inhibition of viral replications by universal receptor T cells
    • Yang OO, Tran A, Kalams SA, Johnson RP, Roberts MR, Walker BD. Lysis of HIV-1 infected cells and inhibition of viral replications by universal receptor T cells. PNAS-USA. 1997b;94:11478-11483.
    • (1997) PNAS-USA , vol.94 , pp. 11478-11483
    • Yang, O.O.1    Tran, A.2    Kalams, S.A.3    Johnson, R.P.4    Roberts, M.R.5    Walker, B.D.6
  • 66
    • 0033590168 scopus 로고    scopus 로고
    • Rapid and efficient cell-to-cell transmission of human immunodeficiency virus infection from monocyte-derived macrophages to peripheral blood lymphocytes
    • Carr JM, Hocking H, Li P, Burrell CJ. Rapid and efficient cell-to-cell transmission of human immunodeficiency virus infection from monocyte-derived macrophages to peripheral blood lymphocytes. Virology. 1999;265:319-329.
    • (1999) Virology , vol.265 , pp. 319-329
    • Carr, J.M.1    Hocking, H.2    Li, P.3    Burrell, C.J.4
  • 67
    • 33645581745 scopus 로고    scopus 로고
    • Technical Report: Dartmouth Medical School Hanover, New Hampshire
    • Hickey WF. The Immunology of the Nervous System. Technical Report: Dartmouth Medical School Hanover, New Hampshire; 1999.
    • (1999) The Immunology of the Nervous System
    • Hickey, W.F.1
  • 68
    • 0035863807 scopus 로고    scopus 로고
    • + T-cell response: Persisting effectors and resting memory T cells
    • + T-cell response: Persisting effectors and resting memory T cells. J Immunol 2001;166:926-935.
    • (2001) J Immunol , vol.166 , pp. 926-935
    • Ahmadzadeh, M.1    Hussain, S.F.2    Farber, D.L.3
  • 69
    • 0034077532 scopus 로고    scopus 로고
    • T cell memory: Heterogeneity and mechanisms
    • Farber DL. T cell memory: Heterogeneity and mechanisms. Clin Immunol. 2000;95(3):173-181.
    • (2000) Clin Immunol. , vol.95 , Issue.3 , pp. 173-181
    • Farber, D.L.1
  • 70
    • 0034043248 scopus 로고    scopus 로고
    • Suppression of acute viremia by short-term postexposure prophylaxis of simian/human immunodeficiency virus SHIV-RT-infected monkeys with a novel reverse transcriptase inhibitor (GW420867) allows for development of potent antiviral immune responses resulting in efficient containment of infection
    • Mori K, Yasutomi Y, Sawada S, Villinger F, Sugama K, Rosenwith B, Heeney JL, Überla K, Yamazaki S, Ansari, AA, Rübsamen-Waigmann H. Suppression of acute viremia by short-term postexposure prophylaxis of simian/human immunodeficiency virus SHIV-RT-infected monkeys with a novel reverse transcriptase inhibitor (GW420867) allows for development of potent antiviral immune responses resulting in efficient containment of infection. J Virol. 2000;74(13):5747-5753.
    • (2000) J Virol. , vol.74 , Issue.13 , pp. 5747-5753
    • Mori, K.1    Yasutomi, Y.2    Sawada, S.3    Villinger, F.4    Sugama, K.5    Rosenwith, B.6    Heeney, J.L.7    Überla, K.8    Yamazaki, S.9    Ansari, A.A.10    Rübsamen-Waigmann, H.11
  • 71
    • 0034724390 scopus 로고    scopus 로고
    • + T cell mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression
    • + T cell mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression. PNAS-USA. 2000;97(7):3503-3508.
    • (2000) PNAS-USA , vol.97 , Issue.7 , pp. 3503-3508
    • Tomaras, G.D.1    Lacey, S.F.2    McDanal, C.B.3    Ferrari, G.4    Weinhold, K.J.5    Greenberg, M.L.6
  • 72
    • 0033868182 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte responses to human immunodeficiency virus: Control and scape
    • Sewell AK, Price DA, Oxenius A, Kelleher AD, Phillips RE. Cytotoxic T lymphocyte responses to human immunodeficiency virus: Control and scape. Stem Cells. 2000;18(4):230-244.
    • (2000) Stem Cells , vol.18 , Issue.4 , pp. 230-244
    • Sewell, A.K.1    Price, D.A.2    Oxenius, A.3    Kelleher, A.D.4    Phillips, R.E.5
  • 73
    • 0035793065 scopus 로고    scopus 로고
    • Suppression of HIV replication in the resting CD4+ T cell reservoir by autologous CD8+ T cells: Implications for the development of therapeutic strategies
    • Chun T, Justement JS, Moir S, Hallahan CW, Ehler LA, Liu S, McLaughlin M, Dybul M, Mican JM, Fauci AS. Suppression of HIV replication in the resting CD4+ T cell reservoir by autologous CD8+ T cells: Implications for the development of therapeutic strategies. PNAS-USA. 2001;98(1):253-258.
    • (2001) PNAS-USA , vol.98 , Issue.1 , pp. 253-258
    • Chun, T.1    Justement, J.S.2    Moir, S.3    Hallahan, C.W.4    Ehler, L.A.5    Liu, S.6    McLaughlin, M.7    Dybul, M.8    Mican, J.M.9    Fauci, A.S.10
  • 75
    • 0026054892 scopus 로고    scopus 로고
    • Quiescent T lymphocytes as an inducible virus reservoir in HIV-1 infection
    • Bukrinsky MI, Stanwick TL, Dempsey MP, Stevenson M. Quiescent T lymphocytes as an inducible virus reservoir in HIV-1 infection. Science. 2001;254:423-426.
    • (2001) Science , vol.254 , pp. 423-426
    • Bukrinsky, M.I.1    Stanwick, T.L.2    Dempsey, M.P.3    Stevenson, M.4
  • 77
    • 0030858617 scopus 로고    scopus 로고
    • Pol gene diversity of five human immunodeficiency virus type 1 sub-types: Evidence for naturally occurring mutations that contribute to drug resistance, limited recombination patterns, and common ancestry for subtypes B and D
    • Cornelissen M, Burg R, Zorgdrager F, Lukashov V, Goudsmit J. Pol gene diversity of five human immunodeficiency virus type 1 sub-types: Evidence for naturally occurring mutations that contribute to drug resistance, limited recombination patterns, and common ancestry for subtypes B and D. J Virol. 1997;71(9):6348-6358.
    • (1997) J Virol. , vol.71 , Issue.9 , pp. 6348-6358
    • Cornelissen, M.1    Burg, R.2    Zorgdrager, F.3    Lukashov, V.4    Goudsmit, J.5
  • 78
    • 0032546809 scopus 로고    scopus 로고
    • Limitations of a molecular clock applied to considerations of the origin of HIV-1
    • Korber B, Theiler J, Wolinsky S. Limitations of a molecular clock applied to considerations of the origin of HIV-1. Science. 1998;280:1868-1871.
    • (1998) Science , vol.280 , pp. 1868-1871
    • Korber, B.1    Theiler, J.2    Wolinsky, S.3
  • 80
    • 0035810898 scopus 로고    scopus 로고
    • Genetic drift and within-host metapopulation dynamics of HIV-1 infection
    • Frost SDW, Dumaurier M, Wain-Hobson S, Brown AJL. Genetic drift and within-host metapopulation dynamics of HIV-1 infection. PNAS-USA. 2001;98(12):6975-6980.
    • (2001) PNAS-USA , vol.98 , Issue.12 , pp. 6975-6980
    • Frost, S.D.W.1    Dumaurier, M.2    Wain-Hobson, S.3    Brown, A.J.L.4
  • 82
    • 0034963036 scopus 로고    scopus 로고
    • Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine
    • Lennerstrand J, Stammers DK, Larder BA. Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine. Antimicrob Agents Chemother. 2001;45(7):2144-2146.
    • (2001) Antimicrob Agents Chemother. , vol.45 , Issue.7 , pp. 2144-2146
    • Lennerstrand, J.1    Stammers, D.K.2    Larder, B.A.3
  • 83
    • 0029075130 scopus 로고
    • Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase
    • Mansky LM, Temin HM. Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J Virol. 1995;69(8):5087-5094.
    • (1995) J Virol. , vol.69 , Issue.8 , pp. 5087-5094
    • Mansky, L.M.1    Temin, H.M.2
  • 86
    • 0033819048 scopus 로고    scopus 로고
    • Evidence of a role for the Q151L mutation and the viral background in development of multiple dideoxynucleoside-resistant human immunodeficiency virus type 1
    • García-Lerma JG, Gerrish PJ, Wright AC, Qari SH, Heneine W. Evidence of a role for the Q151L mutation and the viral background in development of multiple dideoxynucleoside-resistant human immunodeficiency virus type 1. J Virol. 2000;74(20):9339-9346.
    • (2000) J Virol. , vol.74 , Issue.20 , pp. 9339-9346
    • García-Lerma, J.G.1    Gerrish, P.J.2    Wright, A.C.3    Qari, S.H.4    Heneine, W.5
  • 88
    • 0025459923 scopus 로고
    • A combined penalty function and outer approximation method for MINLP optimization
    • Viswanathan J, Grossmann IE. A combined penalty function and outer approximation method for MINLP optimization. Comp Chem Eng. 1990;14(7):769-782.
    • (1990) Comp Chem Eng. , vol.14 , Issue.7 , pp. 769-782
    • Viswanathan, J.1    Grossmann, I.E.2
  • 91
    • 0043046995 scopus 로고    scopus 로고
    • Numerical methods of nonlinear optimal control based on mathematical programming
    • Ito S. Numerical methods of nonlinear optimal control based on mathematical programming. Nonlinear Anal Theory Meth and Appl. 1997;30(6):3843-3854.
    • (1997) Nonlinear Anal Theory Meth and Appl. , vol.30 , Issue.6 , pp. 3843-3854
    • Ito, S.1
  • 93
    • 0004123519 scopus 로고    scopus 로고
    • ILOG Inc. ILOG Solver 4.4 - User's Manual; 1999.
    • (1999) User's Manual
  • 94
    • 4043106821 scopus 로고    scopus 로고
    • Haarlem, The Netherlands: Paragon Decision Technology B.V.
    • Bisschop J, Roelofs M. AIMMS - The User's Guide. Haarlem, The Netherlands: Paragon Decision Technology B.V.; 2004.
    • (2004) AIMMS - The User's Guide
    • Bisschop, J.1    Roelofs, M.2
  • 95
    • 0035120581 scopus 로고    scopus 로고
    • Release of virus from lymphoid tissue affects human immunodeficiency virus type 1 and hepatitis C virus kinetics in the blood
    • Müller V, Marée AFM, De Boer RJ. Release of virus from lymphoid tissue affects human immunodeficiency virus type 1 and hepatitis C virus kinetics in the blood. J Virol. 2001;75(6):2597-2603.
    • (2001) J Virol. , vol.75 , Issue.6 , pp. 2597-2603
    • Müller, V.1    Marée, A.F.M.2    De Boer, R.J.3
  • 97
    • 0031155367 scopus 로고    scopus 로고
    • Dynamics of HIV-1 replication in vivo
    • Ho DD. Dynamics of HIV-1 replication in vivo. J Clin Invest. 1997;99(11):2565-2567.
    • (1997) J Clin Invest. , vol.99 , Issue.11 , pp. 2565-2567
    • Ho, D.D.1
  • 98
    • 0024506156 scopus 로고
    • Cell-to-cell transmission of human immunodeficiency virus type 1 in the presence of azidothymidine and neutralizing antibody
    • Gupta P, Balachandran R, Ho M, Enrico A, Rinaldo C. Cell-to-cell transmission of human immunodeficiency virus type 1 in the presence of azidothymidine and neutralizing antibody. J Virol. 1989;63(5):2361-2365.
    • (1989) J Virol. , vol.63 , Issue.5 , pp. 2361-2365
    • Gupta, P.1    Balachandran, R.2    Ho, M.3    Enrico, A.4    Rinaldo, C.5
  • 100
    • 0029940354 scopus 로고    scopus 로고
    • Viral counts count in HIV infection
    • Ho DD. Viral counts count in HIV infection. Science. 1996;272:1124-1125.
    • (1996) Science , vol.272 , pp. 1124-1125
    • Ho, D.D.1
  • 102
    • 0034469259 scopus 로고    scopus 로고
    • An in-vitro rapid-turnover assay for human immunodeficiency virus type 1 replication selects for cell-to-cell spread of virus
    • Gummuluru S, Kinsey CM, Emerman M. An in-vitro rapid-turnover assay for human immunodeficiency virus type 1 replication selects for cell-to-cell spread of virus. J Virol. 2000;74(23):10882-10891.
    • (2000) J Virol. , vol.74 , Issue.23 , pp. 10882-10891
    • Gummuluru, S.1    Kinsey, C.M.2    Emerman, M.3
  • 103
    • 0035412370 scopus 로고    scopus 로고
    • + T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection
    • + T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection. Blood. 2001;98(1):156-164.
    • (2001) Blood , vol.98 , Issue.1 , pp. 156-164
    • Chen, G.1    Shankar, P.2    Lange, C.3    Valdez, H.4    Skolnik, P.R.5    Wu, L.6    Manjunath, N.7    Lieberman, J.8
  • 105
    • 0032568603 scopus 로고    scopus 로고
    • Multiple modes of cellular activation and virus transmission in HIV infection: A role for chronically and latently infected cells in sustaining viral replication
    • Grossman Z, Fejnberg MB, Paul WE. Multiple modes of cellular activation and virus transmission in HIV infection: A role for chronically and latently infected cells in sustaining viral replication. Immunology. 1998;95(11):6314- 6319.
    • (1998) Immunology , vol.95 , Issue.11 , pp. 6314-6319
    • Grossman, Z.1    Fejnberg, M.B.2    Paul, W.E.3
  • 108
    • 0031984787 scopus 로고    scopus 로고
    • Analysis of the temporal relationship between human immunodeficiency virus Type 1 quasispecies in sequential blood samples and various organs obtained at autopsy
    • Van't Wout AB, Ran LJ, Kuiken CL, Kooststra NA, Pals ST, Schuitemaker H. Analysis of the temporal relationship between human immunodeficiency virus Type 1 quasispecies in sequential blood samples and various organs obtained at autopsy. J Virol. 1998;72(1):488-496.
    • (1998) J Virol. , vol.72 , Issue.1 , pp. 488-496
    • Van't Wout, A.B.1    Ran, L.J.2    Kuiken, C.L.3    Kooststra, N.A.4    Pals, S.T.5    Schuitemaker, H.6
  • 109
    • 0023740027 scopus 로고    scopus 로고
    • HIV is not the cause of AIDS
    • Duesberg P. HIV is not the cause of AIDS. Science. 1998;241:514-517.
    • (1998) Science , vol.241 , pp. 514-517
    • Duesberg, P.1
  • 111
    • 0032889037 scopus 로고    scopus 로고
    • Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates
    • Albright AV, Shieh JTC, Itoh T, Lee B, Pleasure D, O'Connor MJ, Doms RW, González-Scarano F. Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates. J Virol. 1999;73(1):202-213.
    • (1999) J Virol. , vol.73 , Issue.1 , pp. 202-213
    • Albright, A.V.1    Shieh, J.T.C.2    Itoh, T.3    Lee, B.4    Pleasure, D.5    O'Connor, M.J.6    Doms, R.W.7    González-Scarano, F.8
  • 112
    • 0033609149 scopus 로고    scopus 로고
    • Quantification of CD4, CCR5, and CXCR4 levels on lymphocite subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
    • Lee B, Sharron M, Montaner LJ, Weissman D, Doms RW. Quantification of CD4, CCR5, and CXCR4 levels on lymphocite subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. PNAS-USA. 1999;96:5215-5220.
    • (1999) PNAS-USA , vol.96 , pp. 5215-5220
    • Lee, B.1    Sharron, M.2    Montaner, L.J.3    Weissman, D.4    Doms, R.W.5
  • 113
    • 0032578396 scopus 로고    scopus 로고
    • Drug concentration heterogeneity facilitates the evolution of drug resistance
    • Kepler TB, Perelson AS. Drug concentration heterogeneity facilitates the evolution of drug resistance. PNAS-USA. 1998;95:11514-11519.
    • (1998) PNAS-USA , vol.95 , pp. 11514-11519
    • Kepler, T.B.1    Perelson, A.S.2
  • 114
    • 0031954686 scopus 로고    scopus 로고
    • Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1
    • Platt EJ, Wehrly K, Kuhmann SE, Chesebro B, Kabat D. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J Virol. 1998;72(4):2855-2864.
    • (1998) J Virol. , vol.72 , Issue.4 , pp. 2855-2864
    • Platt, E.J.1    Wehrly, K.2    Kuhmann, S.E.3    Chesebro, B.4    Kabat, D.5
  • 118
    • 0031660975 scopus 로고    scopus 로고
    • + lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection
    • + lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection. J Virol. 1998;72(11):9054-9060.
    • (1998) J Virol. , vol.72 , Issue.11 , pp. 9054-9060
    • Kitchen, S.G.1    Korin, Y.D.2    Roth, M.D.3    Landway, A.4    Zack, J.A.5
  • 119
    • 0032532388 scopus 로고    scopus 로고
    • Exposure to bacterial products renders macrophages highly susceptible to T-tropic HIV-1
    • Moriuchi M, Moriuchi H, Turner W, Fauci AS. Exposure to bacterial products renders macrophages highly susceptible to T-tropic HIV-1. J Clin Invest. 1998;102(8):1540-1550.
    • (1998) J Clin Invest. , vol.102 , Issue.8 , pp. 1540-1550
    • Moriuchi, M.1    Moriuchi, H.2    Turner, W.3    Fauci, A.S.4
  • 123
    • 0033775934 scopus 로고    scopus 로고
    • Heterogeneous spectrum of coreceptor usage among variants within a dualtropic human immunodeficiency virus type 1 primary-isolate quasispecies
    • Singh A, Collman RG. Heterogeneous spectrum of coreceptor usage among variants within a dualtropic human immunodeficiency virus type 1 primary-isolate quasispecies. J Virol. 2000;74(21):10229-10235.
    • (2000) J Virol. , vol.74 , Issue.21 , pp. 10229-10235
    • Singh, A.1    Collman, R.G.2
  • 124
    • 0033558275 scopus 로고    scopus 로고
    • Interferon-γ upregulates CCR5 expiession in cord and adult blood mononuclear phagocytes
    • Hariharan D, Douglas SD, Lee B, Lai J, Campbell DE, Ho W. Interferon-γ upregulates CCR5 expiession in cord and adult blood mononuclear phagocytes. Blood. 1999;93(4):1137-1144.
    • (1999) Blood , vol.93 , Issue.4 , pp. 1137-1144
    • Hariharan, D.1    Douglas, S.D.2    Lee, B.3    Lai, J.4    Campbell, D.E.5    Ho, W.6
  • 125
    • 0031901134 scopus 로고    scopus 로고
    • Expression of CCR5 increases during monocyte differentiation and directly mediates macrophage susceptibility to infection by human immunodeficiency virus type 1
    • Tuttle DL, Harrison JK, Anders C, Sleasman JW, Goodenow MM. Expression of CCR5 increases during monocyte differentiation and directly mediates macrophage susceptibility to infection by human immunodeficiency virus type 1. J Virol. 1998;72(6):4962-4969.
    • (1998) J Virol. , vol.72 , Issue.6 , pp. 4962-4969
    • Tuttle, D.L.1    Harrison, J.K.2    Anders, C.3    Sleasman, J.W.4    Goodenow, M.M.5
  • 127
    • 0033120514 scopus 로고    scopus 로고
    • Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling
    • Rabin RL, Park MK, Liao F, Swofford R, Stephany D, Farber JM. Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling. J Immunol. 1999;162:3840-3850.
    • (1999) J Immunol. , vol.162 , pp. 3840-3850
    • Rabin, R.L.1    Park, M.K.2    Liao, F.3    Swofford, R.4    Stephany, D.5    Farber, J.M.6
  • 128
    • 0034659853 scopus 로고    scopus 로고
    • TNF-α-induced secretion of C-C chemokines modulates C-C chemokine receptor 5 expression on peripheral blood lymphocytes
    • Hornung F, Scala G, Lenardo MJ. TNF-α-induced secretion of C-C chemokines modulates C-C chemokine receptor 5 expression on peripheral blood lymphocytes. J Immunol. 2000;164:6180-6187.
    • (2000) J Immunol. , vol.164 , pp. 6180-6187
    • Hornung, F.1    Scala, G.2    Lenardo, M.J.3
  • 129
    • 0035871823 scopus 로고    scopus 로고
    • Coregulation of CXC chemokine receptor and CD4 expression on T lymphocytes during allogeneic activation
    • Ebert LM, McColl SR. Coregulation of CXC chemokine receptor and CD4 expression on T lymphocytes during allogeneic activation. J Immunol. 2001;166:4870-4878.
    • (2001) J Immunol. , vol.166 , pp. 4870-4878
    • Ebert, L.M.1    McColl, S.R.2
  • 130
    • 0031974617 scopus 로고    scopus 로고
    • CCR5 expression correlates with susceptibility of maturing monocytes to human immunodeficiency virus type 1 infection
    • Naif HM, Li S, Alali M, Sloane A, Wu L, Kelly M, Lynch G, Lloyd A, Cunningham AL. CCR5 expression correlates with susceptibility of maturing monocytes to human immunodeficiency virus type 1 infection. J Virol. 1998;72(1):830-836.
    • (1998) J Virol. , vol.72 , Issue.1 , pp. 830-836
    • Naif, H.M.1    Li, S.2    Alali, M.3    Sloane, A.4    Wu, L.5    Kelly, M.6    Lynch, G.7    Lloyd, A.8    Cunningham, A.L.9
  • 132
    • 0032993044 scopus 로고    scopus 로고
    • Expression and use of human immunodeficiency virus type 1 coreceptors by human alveolar macrophages
    • Worgall S, Connor R, Kaner RJ, Fenamore E, Sheridan K, Singh R, Crystal RG. Expression and use of human immunodeficiency virus type 1 coreceptors by human alveolar macrophages. J Virol. 1999; 73(7):5865-5874.
    • (1999) J Virol. , vol.73 , Issue.7 , pp. 5865-5874
    • Worgall, S.1    Connor, R.2    Kaner, R.J.3    Fenamore, E.4    Sheridan, K.5    Singh, R.6    Crystal, R.G.7
  • 133
    • 0033059948 scopus 로고    scopus 로고
    • Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4
    • Esté JA, Cabrera C, Blanco J, Gutierrez A, Bridger G, Henson G, Clotet B, Schols D, De Clercq E. Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4. J Virol. 1999;73(7):5577-5585.
    • (1999) J Virol. , vol.73 , Issue.7 , pp. 5577-5585
    • Esté, J.A.1    Cabrera, C.2    Blanco, J.3    Gutierrez, A.4    Bridger, G.5    Henson, G.6    Clotet, B.7    Schols, D.8    De Clercq, E.9
  • 134
    • 19444385717 scopus 로고    scopus 로고
    • CXCR4 and CCR5 regulation and expression patterns on T- And monocyte-macrophage cell lineages: Implications for susceptibility to infection by HIV-1
    • Joly M, Pinto JM. CXCR4 and CCR5 regulation and expression patterns on T- and monocyte-macrophage cell lineages: Implications for susceptibility to infection by HIV-1. Math Biosc. 2005:195:92-126.
    • (2005) Math Biosc. , vol.195 , pp. 92-126
    • Joly, M.1    Pinto, J.M.2
  • 136
    • 0031056631 scopus 로고    scopus 로고
    • Expression pattern of HIV-1 coreceptors on T cells: Implications for viral transmission and lymphocyte homing
    • Unutmaz D, Littman DR. Expression pattern of HIV-1 coreceptors on T cells: Implications for viral transmission and lymphocyte homing. PNAS-USA. 1997;94:1615-1618.
    • (1997) PNAS-USA , vol.94 , pp. 1615-1618
    • Unutmaz, D.1    Littman, D.R.2
  • 137
    • 0026600926 scopus 로고
    • Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population
    • Schuitemaker H, Koot M, Koostra NA, Dercksen MW, Goede RE, van Steenwijk RP, Lange JM, Schattenkerk JK, Miedema F, Tersmette M. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population. J Virol. 1992;66(3):1354-1360.
    • (1992) J Virol. , vol.66 , Issue.3 , pp. 1354-1360
    • Schuitemaker, H.1    Koot, M.2    Koostra, N.A.3    Dercksen, M.W.4    Goede, R.E.5    Van Steenwijk, R.P.6    Lange, J.M.7    Schattenkerk, J.K.8    Miedema, F.9    Tersmette, M.10
  • 140
    • 0030220831 scopus 로고    scopus 로고
    • The SCID-hu mouse: An in-vivo model for HIV-1 pathogenesis and stem cell gene therapy for AIDS
    • Jamieson BD, Aldrovandi GM, Zack JA. The SCID-hu mouse: An in-vivo model for HIV-1 pathogenesis and stem cell gene therapy for AIDS. Immunology. 1996;8:215-221.
    • (1996) Immunology , vol.8 , pp. 215-221
    • Jamieson, B.D.1    Aldrovandi, G.M.2    Zack, J.A.3
  • 143
    • 0034329318 scopus 로고    scopus 로고
    • Mechanisms of HIV-associated lymphocyte apoptosis
    • Badley AD, Pilon AA, Landay A, Lynch DH. Mechanisms of HIV-associated lymphocyte apoptosis. Blood. 2000;96(9):2951-2964.
    • (2000) Blood , vol.96 , Issue.9 , pp. 2951-2964
    • Badley, A.D.1    Pilon, A.A.2    Landay, A.3    Lynch, D.H.4
  • 144
    • 0032978963 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/Caspase-8
    • Bartz SR, Emerman M. Human immunodeficiency virus type 1 tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/Caspase-8. J Virol. 1999;73(3):1956-1963.
    • (1999) J Virol. , vol.73 , Issue.3 , pp. 1956-1963
    • Bartz, S.R.1    Emerman, M.2
  • 145
    • 0029091047 scopus 로고
    • + T cells are infectible by human immunodeficiency virus but do not release virus after activation
    • + T cells are infectible by human immunodeficiency virus but do not release virus after activation. J Virol. 1995;69(9):5659-5665.
    • (1995) J Virol. , vol.69 , Issue.9 , pp. 5659-5665
    • Tang, S.1    Patterson, B.2    Levy, J.A.3
  • 146
    • 0027244932 scopus 로고
    • Infection of human monocyte-derived macrophages by human immunodeficiency virus mediated by cell-to-cell transmission
    • St Luce S, Arts E, Geleziunas R, Bour S, Weinberg MA. Infection of human monocyte-derived macrophages by human immunodeficiency virus mediated by cell-to-cell transmission. J Med Virol. 1993;41:71-78.
    • (1993) J Med Virol. , vol.41 , pp. 71-78
    • St Luce, S.1    Arts, E.2    Geleziunas, R.3    Bour, S.4    Weinberg, M.A.5
  • 148
    • 0030069875 scopus 로고    scopus 로고
    • + T Lymphocytes Results in Altered T Cell Responses with Enhanced Production of IFN-γ and IL-10
    • + T Lymphocytes Results in Altered T Cell Responses with Enhanced Production of IFN-γ and IL-10. Virology. 1996;215:51-60.
    • (1996) Virology , vol.215 , pp. 51-60
    • Ludewig, B.1    Gelderblom, H.R.2    Becker, Y.3    Schäfer, A.4    Pauli, G.5
  • 149
    • 0030026113 scopus 로고    scopus 로고
    • Reduction of HIV concentration during acute infection: Independence from a specific immune response
    • Phillips AN. Reduction of HIV concentration during acute infection: Independence from a specific immune response. Science. 1996;271:497-499.
    • (1996) Science , vol.271 , pp. 497-499
    • Phillips, A.N.1
  • 151
    • 0032556667 scopus 로고    scopus 로고
    • A stochastic model for early HIV-1 population dynamics
    • Tuckwell HC, Le Corfec E. A stochastic model for early HIV-1 population dynamics. J Theor Biol. 1998;195:451-463.
    • (1998) J Theor Biol. , vol.195 , pp. 451-463
    • Tuckwell, H.C.1    Le Corfec, E.2
  • 152
    • 0034161584 scopus 로고    scopus 로고
    • Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor β chain repertoire and reduces the level of T-cell oligoclonality
    • Soudeyns H, Campi G, Rizzardi GP, Lenge C, Demarest JF, Tambussi G, Lazzarin A, Kaufmann D, Casorati G, Corey L, Pantaleo G. Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor β chain repertoire and reduces the level of T-cell oligoclonality. Blood. 2000;95(5):1743-1751.
    • (2000) Blood , vol.95 , Issue.5 , pp. 1743-1751
    • Soudeyns, H.1    Campi, G.2    Rizzardi, G.P.3    Lenge, C.4    Demarest, J.F.5    Tambussi, G.6    Lazzarin, A.7    Kaufmann, D.8    Casorati, G.9    Corey, L.10    Pantaleo, G.11
  • 153
    • 0029833722 scopus 로고    scopus 로고
    • Anti-CD4 therapy for AIDS suggested by mathematical models
    • De Boer RJ, Boucher CAB. Anti-CD4 therapy for AIDS suggested by mathematical models. Proc Roy Soc London B. 1996;263:899-905.
    • (1996) Proc Roy Soc London B , vol.263 , pp. 899-905
    • De Boer, R.J.1    Boucher, C.A.B.2
  • 154
    • 0032418812 scopus 로고    scopus 로고
    • The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses
    • Kalams SA, Walker BD. The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses. J Exp Med. 1998; 188(12):2199-2204.
    • (1998) J Exp Med. , vol.188 , Issue.12 , pp. 2199-2204
    • Kalams, S.A.1    Walker, B.D.2
  • 155
    • 0033135883 scopus 로고    scopus 로고
    • The dynamics of HTLV-1 and the CTL response
    • Wodarz D, Nowak MA, Bangham CRM. The dynamics of HTLV-1 and the CTL response. Immunology Today. 1999b;20(5):220-227.
    • (1999) Immunology Today , vol.20 , Issue.5 , pp. 220-227
    • Wodarz, D.1    Nowak, M.A.2    Bangham, C.R.M.3
  • 157
    • 0029116868 scopus 로고
    • High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors
    • Rinaldo C, Huang X, Fan Z, Ding M, Beltz L, Logar A, Panicali D, Mazzara G, Liebmann J, Cottrill M, Gupta P. High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors. J Virol. 1995;69(9):5838-5842.
    • (1995) J Virol. , vol.69 , Issue.9 , pp. 5838-5842
    • Rinaldo, C.1    Huang, X.2    Fan, Z.3    Ding, M.4    Beltz, L.5    Logar, A.6    Panicali, D.7    Mazzara, G.8    Liebmann, J.9    Cottrill, M.10    Gupta, P.11
  • 159
    • 0032532595 scopus 로고    scopus 로고
    • Chronically HIV-1-monocytic cells induce apoptosis in cocultured T cells
    • Chen H, Yip YK, George I, Tyorkin M, Salik E, Sperber K. Chronically HIV-1-monocytic cells induce apoptosis in cocultured T cells. J Immunol. 1998;161:4257-4267.
    • (1998) J Immunol. , vol.161 , pp. 4257-4267
    • Chen, H.1    Yip, Y.K.2    George, I.3    Tyorkin, M.4    Salik, E.5    Sperber, K.6
  • 160
    • 0033082513 scopus 로고    scopus 로고
    • Processing of HIV-1 envelope glyprotein for class I-restricted recognition: Dependence on TAP1/2 and mechanisms for cytosolic localization
    • Ferris RL, Hall C, Sipsas NV, Safrit JT, Trocha A, Koup RA, Johnson RP, Siliciano RF. Processing of HIV-1 envelope glyprotein for class I-restricted recognition: Dependence on TAP1/2 and mechanisms for cytosolic localization. J Immunol. 1999;162:1324-1332.
    • (1999) J Immunol. , vol.162 , pp. 1324-1332
    • Ferris, R.L.1    Hall, C.2    Sipsas, N.V.3    Safrit, J.T.4    Trocha, A.5    Koup, R.A.6    Johnson, R.P.7    Siliciano, R.F.8
  • 161
    • 0242707686 scopus 로고    scopus 로고
    • Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1 ENV epitope for endogenous MHC class i antigen presentation
    • López D, Gil-Torregrosa BC, Bergmann C, Del Val M. Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1
    • (2000) J Immunol. , vol.164 , pp. 5070-5077
    • López, D.1    Gil-Torregrosa, B.C.2    Bergmann, C.3    Del Val, M.4
  • 164
    • 0024366777 scopus 로고
    • Mathematical and statistical studies of the epidemiology of HIV
    • Anderson RM. Mathematical and statistical studies of the epidemiology of HIV. AIDS. 1989;3:333-346.
    • (1989) AIDS , vol.3 , pp. 333-346
    • Anderson, R.M.1
  • 165
    • 0003056312 scopus 로고
    • Modeling the interaction of the immune system with HIV
    • C. Castillo-Chavez, Ed. Lecture Notes Biomath. New York: Springer
    • Perelson AS. Modeling the interaction of the immune system with HIV. In: Mathematical and Statistical Approaches to AIDS Epidemiology. C. Castillo-Chavez, Ed. Lecture Notes Biomath. New York: Springer; 1989;83:350-352.
    • (1989) Mathematical and Statistical Approaches to AIDS Epidemiology , vol.83 , pp. 350-352
    • Perelson, A.S.1
  • 166
    • 0742269661 scopus 로고    scopus 로고
    • Global optimization of dynamic systems
    • Papamichail I, Adjiman CS. Global optimization of dynamic systems. Comp Chem Eng. 2004;28(3):403-415.
    • (2004) Comp Chem Eng. , vol.28 , Issue.3 , pp. 403-415
    • Papamichail, I.1    Adjiman, C.S.2
  • 170
    • 84858580032 scopus 로고    scopus 로고
    • accessed in 2002
    • Virco BVBA. The Virtual Phenotype™. Available in: www.virco-lab.com/web/page.asp?id=83&page_id=161 (accessed in 2002).
    • The Virtual Phenotype™
  • 171
    • 0029980114 scopus 로고    scopus 로고
    • Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNA load suppression by zidovudine
    • Jong MD, Veenstra J, Stilianakis NI, Schuurman R, Lange JMA, Boer RJ, Boucher CAB. Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNA load suppression by zidovudine. PNAS-USA. 1996;93:5501-5506.
    • (1996) PNAS-USA , vol.93 , pp. 5501-5506
    • Jong, M.D.1    Veenstra, J.2    Stilianakis, N.I.3    Schuurman, R.4    Lange, J.M.A.5    Boer, R.J.6    Boucher, C.A.B.7
  • 173
    • 0010596116 scopus 로고    scopus 로고
    • Drug metabolism and pharmacokinetics in drug discovery: A primer for bioanalytical chemists, Part II
    • Gunaratna C. Drug metabolism and pharmacokinetics in drug discovery: A primer for bioanalytical chemists, Part II. Current Separations. 2001;19(3):87-92.
    • (2001) Current Separations , vol.19 , Issue.3 , pp. 87-92
    • Gunaratna, C.1
  • 174
    • 84858575432 scopus 로고    scopus 로고
    • accessed in 2001
    • The Body Health Resources Corporation. Drug Side Effects Chart. Available in: http://www.thebody.com/pinf/sideeffectchart.html (accessed in 2001).
    • Drug Side Effects Chart
  • 176
    • 33645562986 scopus 로고    scopus 로고
    • Pharmacogenomic mixed integer dynamic optimization model for viral dynamics in HIV-1/AIDS infection. Part I. Primary (Acute) Infection
    • Indianapolis: November 3-7
    • Joly M, Pinto JM. Pharmacogenomic mixed integer dynamic optimization model for viral dynamics in HIV-1/AIDS infection. Part I. Primary (Acute) Infection. In: AIChE Annual Meeting, Indianapolis: November 3-7; 2002.
    • (2002) AIChE Annual Meeting
    • Joly, M.1    Pinto, J.M.2
  • 179
    • 0034696770 scopus 로고    scopus 로고
    • A condition for successful escape of a mutant after primary HIV infection
    • Monteiro LHA, Gonçalves CHO, Piqueira JRC. A condition for successful escape of a mutant after primary HIV infection. J Theor Biol. 2000;203:399-406.
    • (2000) J Theor Biol. , vol.203 , pp. 399-406
    • Monteiro, L.H.A.1    Gonçalves, C.H.O.2    Piqueira, J.R.C.3
  • 180
    • 0031935146 scopus 로고    scopus 로고
    • Identification of determinants on a dualtropic human immunodeficiency virus type 1 envelope glycoprotein that confer usage of CXCR4
    • Cho MW, Lee MK, Carney MC, Berson JF, Doms RW, Martin MA. Identification of determinants on a dualtropic human immunodeficiency virus type 1 envelope glycoprotein that confer usage of CXCR4. J Virol. 1998;72:2509-2515.
    • (1998) J Virol. , vol.72 , pp. 2509-2515
    • Cho, M.W.1    Lee, M.K.2    Carney, M.C.3    Berson, J.F.4    Doms, R.W.5    Martin, M.A.6
  • 181
    • 0003056310 scopus 로고
    • Modeling the interaction of HIV with cells of the immune system
    • Merrill SJ. Modeling the interaction of HIV with cells of the immune system. Lect Notes Biomath. 1989;83:371.
    • (1989) Lect Notes Biomath. , vol.83 , pp. 371
    • Merrill, S.J.1
  • 182
    • 0026603870 scopus 로고
    • Variability of HIV infections
    • Nowak MA. Variability of HIV infections. J Theor Biol 1992;155:1-20.
    • (1992) J Theor Biol , vol.155 , pp. 1-20
    • Nowak, M.A.1
  • 183
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, Borkowsky W, Farthing C, Ho DD. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol. 1994;68(7):4650-4655.
    • (1994) J Virol. , vol.68 , Issue.7 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3    Andrews, C.A.4    McLeod, G.5    Borkowsky, W.6    Farthing, C.7    Ho, D.D.8
  • 184
    • 0011162675 scopus 로고
    • A new method for reducing cytotoxicity of the anti-AIDS drug AZT
    • DS Levine, Ed. Scientific Publishing
    • Agur Z. A new method for reducing cytotoxicity of the anti-AIDS drug AZT. In: Biomedical Modeling and Simulation. DS Levine, Ed. Scientific Publishing; 1989:59-61.
    • (1989) Biomedical Modeling and Simulation , pp. 59-61
    • Agur, Z.1
  • 185
    • 0026606696 scopus 로고
    • A theoretical analysis of interval drug dosing for cell-cycle-phase- specific drugs
    • Cojocaru L, Agur Z. A theoretical analysis of interval drug dosing for cell-cycle-phase-specific drugs. Math Biosci. 1992;109:85-97.
    • (1992) Math Biosci. , vol.109 , pp. 85-97
    • Cojocaru, L.1    Agur, Z.2
  • 187
    • 0029552931 scopus 로고
    • Zidovudine and HIV: Mathematical models of within-host population dynamics
    • McLean AR, Frost SDW. Zidovudine and HIV: Mathematical models of within-host population dynamics. Rev Med Virol. 1995;5:141-147.
    • (1995) Rev Med Virol. , vol.5 , pp. 141-147
    • McLean, A.R.1    Frost, S.D.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.