메뉴 건너뛰기




Volumn 8, Issue 4, 1996, Pages 215-221

The SCID-hu mouse: An in-vivo model for HIV-1 pathogenesis and stem cell gene therapy for AIDS

Author keywords

AIDS; Animal models; Gene therapy; HIV; SCID hu

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; GENE; GENE THERAPY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; MOUSE; NONHUMAN; PATHOGENESIS; REVIEW; STEM CELL;

EID: 0030220831     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.1996.0027     Document Type: Review
Times cited : (24)

References (43)
  • 1
    • 0023753744 scopus 로고
    • The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function
    • 1. McCune JM, Namikawa R, Kaneshima H, Shultz LD, Lieberman M, Weissman IL (1988) The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function. Science 241:1632-1639
    • (1988) Science , vol.241 , pp. 1632-1639
    • McCune, J.M.1    Namikawa, R.2    Kaneshima, H.3    Shultz, L.D.4    Lieberman, M.5    Weissman, I.L.6
  • 2
    • 0023734130 scopus 로고
    • Transfer of a functional human immune system to mice with severe combined immunodeficiency
    • 2. Mosier DE, Gulizia RJ, Baird SM, Wilson DB (1988) Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 335:256-259
    • (1988) Nature , vol.335 , pp. 256-259
    • Mosier, D.E.1    Gulizia, R.J.2    Baird, S.M.3    Wilson, D.B.4
  • 10
    • 0027772764 scopus 로고
    • Selective thymocyte depletion in neonatal HIV-1 thymic infection
    • 10. Rosenzweig M, Clark DP, Gaulton GN (1993) Selective thymocyte depletion in neonatal HIV-1 thymic infection. AIDS 7:1601-1605
    • (1993) AIDS , vol.7 , pp. 1601-1605
    • Rosenzweig, M.1    Clark, D.P.2    Gaulton, G.N.3
  • 12
    • 0029132016 scopus 로고
    • In vivo pathogenic properties of two clonal human immunodeficiency virus type 1 isolates
    • 12. Jamieson BD, Pang S, Aldrovandi GM, Zha J, Zack JA (1995) in vivo pathogenic properties of two clonal human immunodeficiency virus type 1 isolates. J Virol 69:6259-6264
    • (1995) J Virol , vol.69 , pp. 6259-6264
    • Jamieson, B.D.1    Pang, S.2    Aldrovandi, G.M.3    Zha, J.4    Zack, J.A.5
  • 13
    • 0028125248 scopus 로고
    • Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse
    • 13. Kaneshima H, Su L, Bonyhadi ML, Connor RI, Ho DD, McCune JM (1994) Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse. J Virol 68:8188-8192
    • (1994) J Virol , vol.68 , pp. 8188-8192
    • Kaneshima, H.1    Su, L.2    Bonyhadi, M.L.3    Connor, R.I.4    Ho, D.D.5    McCune, J.M.6
  • 15
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome - Associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • 15. Adachi A, Gendelman HE, Koenig S, Folks T, Willey R, Rabson A, Martin MA (1985) Production of acquired immunodeficiency syndrome - associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol 59:284-291
    • (1985) J Virol , vol.59 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3    Folks, T.4    Willey, R.5    Rabson, A.6    Martin, M.A.7
  • 16
    • 0023214674 scopus 로고
    • Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms
    • 16. Koyanagi Y, Miles S, Mitsuyasu RT, Merrill JE, Ymters HV, Chen ISY(1987) Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 236:819-822
    • (1987) Science , vol.236 , pp. 819-822
    • Koyanagi, Y.1    Miles, S.2    Mitsuyasu, R.T.3    Merrill, J.E.4    Ymters, H.V.5    Chen, I.S.Y.6
  • 17
    • 0026552401 scopus 로고
    • Rapid generation of sequence variation during primary HIV-1 infection
    • 17. Pang S, Shlesinger Y, Daar ES, Moudgil T, Ho DD, Chen ISY (1992) Rapid generation of sequence variation during primary HIV-1 infection. AIDS 6:453-460
    • (1992) AIDS , vol.6 , pp. 453-460
    • Pang, S.1    Shlesinger, Y.2    Daar, E.S.3    Moudgil, T.4    Ho, D.D.5    Chen, I.S.Y.6
  • 18
    • 0029150052 scopus 로고
    • HIV accessory proteins: Leading roles for the supporting cast
    • 18. Trono D (1995) HIV accessory proteins: Leading roles for the supporting cast. Cell 82:189-192
    • (1995) Cell , vol.82 , pp. 189-192
    • Trono, D.1
  • 20
    • 0027043276 scopus 로고
    • Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
    • 20. Daniel MD, Kirchoff F, Czajak SC, Sehgal PK, Desrosiers RC (1992) Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258:1938-1941
    • (1992) Science , vol.258 , pp. 1938-1941
    • Daniel, M.D.1    Kirchoff, F.2    Czajak, S.C.3    Sehgal, P.K.4    Desrosiers, R.C.5
  • 21
    • 0029670763 scopus 로고    scopus 로고
    • Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice
    • 21. Aldrovandi GM, Zack JA (1996) Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice. J Virol 70:1505-1511
    • (1996) J Virol , vol.70 , pp. 1505-1511
    • Aldrovandi, G.M.1    Zack, J.A.2
  • 22
    • 0028878783 scopus 로고
    • Proline-rich (P X X P) motifs in HIV-1 nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
    • 22. Saksela K, Cheng G, Baltimore D (1995) Proline-rich (P X X P) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4. EMBO J 14:484-491
    • (1995) EMBO J , vol.14 , pp. 484-491
    • Saksela, K.1    Cheng, G.2    Baltimore, D.3
  • 25
    • 0028944667 scopus 로고
    • Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques
    • 25. Baba TW, Jeong YS, Penninck D, Bronson R, Greene MF, Ruprecht RM (1995) Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science 267:1820-1825
    • (1995) Science , vol.267 , pp. 1820-1825
    • Baba, T.W.1    Jeong, Y.S.2    Penninck, D.3    Bronson, R.4    Greene, M.F.5    Ruprecht, R.M.6
  • 26
    • 0024807136 scopus 로고
    • Potential mechanisms for the cytopathic properties of HIV
    • 26. Gary RF (1989) Potential mechanisms for the cytopathic properties of HIV. AIDS 3:683-694
    • (1989) AIDS , vol.3 , pp. 683-694
    • Gary, R.F.1
  • 27
    • 0022444917 scopus 로고
    • A second post-transcriptional trans-activator gene required for HTLV-III replication
    • 27. Sodroski J, Goh WC, Rosen C, Dayton A, Terwillinger E, Haseltine W (1986) A second post-transcriptional trans-activator gene required for HTLV-III replication. Nature 321:412-417
    • (1986) Nature , vol.321 , pp. 412-417
    • Sodroski, J.1    Goh, W.C.2    Rosen, C.3    Dayton, A.4    Terwillinger, E.5    Haseltine, W.6
  • 30
    • 0025163256 scopus 로고
    • Primary cytotoxicity against the envelope glycoprotein of human immunodeficiency virus-1: Evidence for antibody-dependent cellular cytotoxicity in vivo
    • 30. Tanneau R, McChesneyM, Lopez O, Sonsonetti P, Montagnier L, Riviere Y (1990) Primary cytotoxicity against the envelope glycoprotein of human immunodeficiency virus-1: Evidence for antibody-dependent cellular cytotoxicity in vivo. J Infect Dis 162:837-843
    • (1990) J Infect Dis , vol.162 , pp. 837-843
    • Tanneau, R.1    Lopez, O.2    Sonsonetti, P.3    Montagnier, L.4    Riviere, Y.5
  • 32
    • 0025830099 scopus 로고
    • Apoptosis as a mechanism of cell death in cultured lymphoblasts acutely infected with HIV-1
    • 32. Terai C, Kornbluth RS, Pauza CD, Richmann DD, Carson DA (1991) Apoptosis as a mechanism of cell death in cultured lymphoblasts acutely infected with HIV-1. J Clin Invest 87:1710-1715
    • (1991) J Clin Invest , vol.87 , pp. 1710-1715
    • Terai, C.1    Kornbluth, R.S.2    Pauza, C.D.3    Richmann, D.D.4    Carson, D.A.5
  • 33
    • 0028970284 scopus 로고
    • HIV-1-induced thymocyte depletion is associated with indirect cytopathicity and infection of progenitor cells in vivo
    • 33. Su L, Kaneshima H, Bonyhadi M, Salimi S, Kraft D, Rabin L, McCune JM (1995) HIV-1-induced thymocyte depletion is associated with indirect cytopathicity and infection of progenitor cells in vivo. Immunity 2:25-36
    • (1995) Immunity , vol.2 , pp. 25-36
    • Su, L.1    Kaneshima, H.2    Bonyhadi, M.3    Salimi, S.4    Kraft, D.5    Rabin, L.6    McCune, J.M.7
  • 34
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • 34. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 35
    • 0028261732 scopus 로고
    • Flow cytometric detection of apoptosis: Comparison of the assays of in situ DNA degradation and chromatin changes
    • 35. Hotz AH, Gong J, Traganos F, Darzynkiewicz A (1994) Flow cytometric detection of apoptosis: Comparison of the assays of in situ DNA degradation and chromatin changes. Cytometry 15:237-244
    • (1994) Cytometry , vol.15 , pp. 237-244
    • Hotz, A.H.1    Gong, J.2    Traganos, F.3    Darzynkiewicz, A.4
  • 36
    • 0027269557 scopus 로고
    • Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
    • 36. Gorczyca W, Gong J, Darzynkiewicz Z (1993) Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res 53:1945-1951
    • (1993) Cancer Res , vol.53 , pp. 1945-1951
    • Gorczyca, W.1    Gong, J.2    Darzynkiewicz, Z.3
  • 37
    • 0027261147 scopus 로고
    • The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor assays
    • 37. Gorczyca W, Gong J, Ardelt B, Traganos F, Darzynkiewicz Z (1993) The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor assays. Cancer Res 53:3186-3192
    • (1993) Cancer Res , vol.53 , pp. 3186-3192
    • Gorczyca, W.1    Gong, J.2    Ardelt, B.3    Traganos, F.4    Darzynkiewicz, Z.5
  • 38
    • 0028295351 scopus 로고
    • A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry
    • 38. Schmid I, Uittenbogaart CH, Keld B, Giorgi JV (1994) A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry. J Immunol Methods 170:145-157
    • (1994) J Immunol Methods , vol.170 , pp. 145-157
    • Schmid, I.1    Uittenbogaart, C.H.2    Keld, B.3    Giorgi, J.V.4
  • 39
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • 39. Fadok VA, Voelker DR, Campbell PAS, Cohen JJ, Bratton DL, Henson PM (1992) Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 148:2207-2216
    • (1992) J Immunol , vol.148 , pp. 2207-2216
    • Fadok, V.A.1    Voelker, D.R.2    Campbell, P.A.S.3    Cohen, J.J.4    Bratton, D.L.5    Henson, P.M.6
  • 41
    • 0029043888 scopus 로고
    • A novel assay for apoptosis flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
    • 41. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C (1995) A novel assay for apoptosis flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 184:39-51
    • (1995) J Immunol Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 43
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer
    • 43. Miller AD, Rosman GJ (1989) Improved retroviral vectors for gene transfer. Biotechniques 7:980-990
    • (1989) Biotechniques , vol.7 , pp. 980-990
    • Miller, A.D.1    Rosman, G.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.