JE-2147: A dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistant HIV-1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 15, 1999, Pages 8675-8680

  Yoshimura, Kazuhisa ^a   Kato, Ryohei ^a,c,d   Yusa, Keisuke ^a   Kavlick, Mark F ^a   Maroun, Victor ^a   Nguyen, Aline ^a   Mimoto, Tsutomu ^d   Ueno, Takamasa ^d   Shintani, Makoto ^d   Falloon, Judith ^b   Masur, Henry ^b   Hayashi, Hideya ^d   Erickson, John ^c   Mitsuya, Hiroaki ^a,c,e  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c SAIC FREDERICK INC   (United States)

^d JAPAN ENERGY CORPORATION   (Japan)

^e KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 2 HYDROXY 4 PHENYLBUTYRIC ACID; ABACAVIR; AMPRENAVIR; DIDANOSINE; DIPEPTIDE; INDINAVIR; JE 2147; KYNOSTATIN 272; LAMIVUDINE; LOPINAVIR; NELFINAVIR; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; UNCLASSIFIED DRUG; ZIDOVUDINE;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT FAILURE; VIRUS INHIBITION;

ADULT; AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CELL LINE; CLONING, MOLECULAR; DIPEPTIDES; DRUG DESIGN; DRUG RESISTANCE; HIV PROTEASE; HIV PROTEASE INHIBITORS; HUMANS; MALE; MIDDLE AGED; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTATION; OLIGOPEPTIDES; PHENYLBUTYRATES; REVERSE TRANSCRIPTASE INHIBITORS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; RNA VIRUSES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 13044254785     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.15.8675     Document Type: Article

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