Drug concentration heterogeneity facilitates the evolution of drug resistance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 20, 1998, Pages 11514-11519

  Kepler, Thomas B ^a   Perelson, Alan S ^b  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

HIV; Sanctuary sites

Indexed keywords

INDINAVIR;

ARTICLE; COMPARTMENT MODEL; EVOLUTION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PATHOGENESIS; PRIORITY JOURNAL;

ANTI-HIV AGENTS; DRUG RESISTANCE, MICROBIAL; EVOLUTION; HIV INFECTIONS; HIV-1; HUMANS; MATHEMATICS; MODELS, BIOLOGICAL; MUTATION; VIRUS REPLICATION;

EID: 0032578396     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.20.11514     Document Type: Article

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