Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling

Journal of Immunology

Volumn 162, Issue 7, 1999, Pages 3840-3850

  Rabin, Ronald L ^a   Park, Matthew K ^a   Liao, Fang ^a   Swofford, Ruth ^a   Stephany, David ^a   Farber, Joshua M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; T LYMPHOCYTE RECEPTOR;

ARTICLE; CALCIUM TRANSPORT; CHEMOTAXIS; HUMAN; HUMAN CELL; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DENSITY; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

CALCIUM; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; HUMANS; IMMUNOLOGIC MEMORY; INTERPHASE; LIGANDS; LYMPHOCYTE ACTIVATION; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS;

EID: 0033120514     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Butcher, E. C., and L. J. Picker. 1996. Lymphocyte homing and homeostasis. Science 272:60.
2. Springer, T. A. 1995. Traffic signals on endotheliutn for lymphocyte recirculation and leukocyte emigration. Annu. Rev. Physiol. 57:827.
3. Morse, S. I., and B. A. Barren. 1970. Studies on the leukocytosis and lymphocytosis induced by Bordetella pertussis. III. The distribution of transfused lymphocytes in pertussis-treated and normal mice. J. Exp. Med. 132:663.
4. Wardlaw, A. C., and R. Parton. 1982. Bordetella pertussis toxins. Pharmacol. Ther. 19:1.
5. Bargaue, R. F., and E. C. Butcher. 1993. Rapid G protein-regulated activation event involved in lymphocyte hinding to high endothelial venules. J. Exp. Med. 178:367.
6. Murphy, P. M. 1994. The molecular biology of leukocyte chemoattractant receptors. Annu. Rev. Immunol. 12:593.
7. Hedrick, J. A., and A. Zlotnik. 1996. Chemokines and lymphocyte biology. Curr. Opin. Immunol. 8:343.
8. Mackay, C. R. 1996. Chemokine receptors and T cell chemotaxis. J. Exp. Med. 184:799.
9. Schall, T. J., K. Bacon, K. J. Toy, and D. V. Goeddel. 1990. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 347:669.
10. Schall, T. J., K. Bacon, R. D. Camp, J. W. Kaspari, and D. V. Goeddel. 1993. Human macrophage inflammatory protein a (MIP-1α) and MIP-1β chemokines attract distinct populations of lymphocytes. J. Exp. Med. 177:1821.
11. + T cells in response to MIP-1α and MIP-1β. Science 260:355.
12. Tanaka, Y., D. H. Adams, S. Hubscher, H. Hirano, U. Siebenlist, and S. Shaw. 1993. T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1β. Nature 361:79.
13. Carr, M. W., S. J. Roth, E. Luther, S. S. Rose, and T. A. Springer. 1994. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chcmoattractant. Proc. Natl. Acad. Sci. USA 91:3652.
14. Roth, S. J., M. W. Carr. and T. A. Springer. 1995. C-C chemokines, but not the C-X-C chemokines interleukin-8 and interferon-gamma inducible protein-10. stimulate transendothelial chemotaxis of T lymphocytes. Eur. J. Immunol. 25: 3482.
15. Qin, S., G. LaRosa, J. J. Campbell, H. Smith-Heath, N. Kassam, S. Xiaojie, L. Zeng, E. C. Butcher, and C. R. Mackay. 1996. Expression of monocyte chemoaltractant protein-1 and interleukin-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential. Eur. J. Immunol. 26:640.
16. Adema, G. J., F. Hangers, R. Verstraten, E. de Vries, G. Marland, S. Menon, J. Foster, Y. Xu, P. Nooyen, T. McClanahan, K. B. Bacon, et al. 1997. A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature 387:713.
17. Mayor, S., K. G. Rothberg, and F. R. Maxfield. 1994. Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science 264:1948.
18. + T lymphocytes. FASEB J. 8:1055.
19. Loetscher, P., M. Seitz, M. Baggiolini, and B. Moser. 1996. Interleukin-2 regulates CC chemokine receptor expression and chemolactic responsiveness in T lymphocytes. J. Exp. Med. 184:569.
20. Chang, M., J. McNinch, C. Elias III. C. L. Manthey, D. Grosshans, T. Meng, T. Boone, and D. P. Andrew. 1997. Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes. J. Biol. Chem. 272:25229.
21. Liao, F., R. L. Rabin, J. R. Yannelli, L. G. Koniaris, P. Vanguri, and J. M. Farber. 1995. Human Mig chemokine: biochemical and functional characterization. J. Exp. Med. 182:1301.
22. Loctseher, M., B. Gerber, P. Loelscher, S. A. Jones, L. Piali, I. Clark-Lewis, M. Baggiolini, and B. Moser. 1996. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J. Exp. Med. 184:963.
23. Bleul, C. C., L. Wu, J. A. Hoxie, T. A. Springer, and C. R. Mackay. 1997. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc. Natl. Acad. Sci. USA 94:1925.
24. Su, S. B., N. Mukaida, J. Wang, H. Nomura, and K. Matsushima. 1996. Preparation of specific polyclonal antibodies to a C-C chemokine receptor. CCR1, and determination of CCR1 expression on various types of leukocytes. J. Leukocyte Biol. 60:658.
25. Forster, R., T. Emrich, E. Kremmer, and M. Lipp. 1994. Expression of the G-protein-coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells. Blood 84:830.
26. Qin, S., J. B. Roltman, P. Myers, N. Kassam, M. Weinblalt, M. Loctseher. A. E. Koch, B. Moser, and C. R. Mackay. 1998. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J. Clin. Invest. 101:746.
27. Frade, J. M., M. Mellado, G. del Real, J. C. Gutierrez-Ramos, P. Lind, and A. C. Martinez. 1997. Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells. J. Immunol. 159:5576.
28. Sallusto, F., C. R. Mackay, and A. Lanzavecchia. 1997. Selective expression of the cotaxin receptor CCR3 by human T helper 2 cells. Science 277:2005.
29. Sallusto, F., D. Lenig, C. R. Mackay, and A. Lanzavecchia. 1998. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J. Exp. Med. 187:875.
30. Wu, L., W. A. Paxton, N. Kassam, N. Rutting, J. B. Rottman, N. Sullivan, H. Choe, J. Sodroski, W. Newman, R. A. Koup. et al. 1997. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J. Exp. Med. 185:1681.
31. + human bone marrow cells. J. Immunol. 159:895.
32. Yannelli, J. R., C. Hyatl, S. Johnson, P. Hwu, and S. A. Rosenberg. 1993. Characterization of human tumor cell lines transduced with the cDNA encoding either tumor necrosis factor α (TNF-α) or interleukin-2 (IL-2). J. Immunol. Methods 161:77.
33. Rabinovitch, P. S., C. H. June, A. Grossmann, and J. A. Ledbelter. 1986. Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3: simultaneous use of indo-1 and immunofluorescence with flow cytometry. J. Immunol. 137:952.
34. Rabin, R. L., M. Roederer, Y. Maldonado, A. Petru, L. A. Herzenberg, and L. A. Herzenherg. 1995. Altered representation of naive and memory CD8 T cell subsets in HIV-inlected children. J. Clin. Immunol. 95:2054.
35. Mackay, C. R., W. Marston, and L. Dudler. 1992. Altered patterns of T cell migration through lymph nodes and skin following antigen challenge. Eur. J. Immunol 22:2205.
36. Bleul, C. C., M. Farzan, H. Choe, C. Parolin, I. Clark-Lewis, J. Sodroski, and T. A. Springer. 1996. The lymphocyte chemoatlractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 382:829.
37. Bleul, C. C., R. C. Fuhlbrigge, J. M. Casasnovas, A. Aiuti, and T. A. Springer. 1996. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J. Exp. Med. 184:1101.
38. Campbell, J. J., J. Hedrick, A. Zlotnik, M. A. Siani, D. A. Thompson, and E. C. Butcher. 1998. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 279:381.
39. Farber, J. M. 1997. Mig and IP-10: CXC chemokines that target lymphocytes. J. Leukocyte Biol. 61:246.
40. Cole, K. E., C. A. Strict, T. J. Paradis, K. T. Ogbome, M. Loetscher, R. P. Gladue, W. Lin, J. G. Boyd, B. Moser, D. E. Wood, et al. 1998. Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J. Exp. Med. 187:2009.
41. Bonecchi, R., G. Bianchi, P. P. Bordignon, D. D'Amhrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P. A. Gray, A. Mantovani, et al. 1998. Differential expression of chemokine receptors and chemotactic responsiveness of type I T helper cells (Th1s) and Th2s. J. Exp. Med. 187:129.
42. Liao, F., G. Alkhatib, K. W. Peden, G. Sharma, E. A. Berger, and J. M. Farber, 1997. STRL33. A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-I. J. Exp. Med. 185:2015.
43. Leung, D. Y., M. Gately, A. Trumble, B. Ferguson-Darnell, P. M. Schlievert, and L. J. Picker. 1995. Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production. J. Exp. Med 181:747.
44. Bouloc, A., A. Cavani, and S. I. Katz. 1998. Contact hypersensitivily in MHC class Il-deficient mice depends on CD8 T lymphocytes primed by immunostimulating Langerhans cells. J. Invest. Dermatol. 111:44.
45. Ebnet, K., M. M. Simon, and S. Shaw. 1996. Regulation of chemokine gene expression in human endothehal cells by proinflammatory cytokines and Borrelia burgdarferi. Ann. NY Acad. Sci. 717:107.
46. Luster, A. D., and J. V. Ravetch. 1987. Biochemical characterization of a y interferon-inducible cytokine (IP-10). J. Exp. Med. 166:1084.
47. Taub, D. D., P. Proost, W. J. Murphy, M. Anver, D. L. Longo, J. van Damme, and J. J. Oppenheim. 1995. Monocyte chemotaetic protein-1 (MCP-1). -2. and -3 are chemotaetic for human T lymphocytes. J. Clin Invest. 95:1370.
48. Maghazachi, A. A. 1997. Role of the heterotrimeric G proteins in stromal-derived factor-1α-induced natural killer cell chemotaxis and calcium mobilization [published erratum appears in Biochem Biophys Res Commun 1997 Aug 28:237(3): 759]. Biochem. Biophys. Res. Commun. 236:270.
49. Maghazachi, A. A., A. al-Aoukaty, and T. J. Schall. 1994. C-C ehemokines induce the chemotaxis of NK and IL-2-acttvated NK cells: role for G proteins. J. Immunol. 153:4969.
50. Taub, D. D., T. J. Sayers, C. R. Carter, and J. R. Ortaldo. 1995. α and β chemokines induce NK cell migration and enhance NK-mediated cytolysis. J. Immunol. 155:3877.
51. Sha'afi, R. I., J. Shefcyk, R. Yassin, T. F. Molski, M. Volpi, P. H. Naccache, J. R. White, M. B. Feinstein, and E. L. Becker. 1986. Is a rise in intracellular concentration of free calcium necessary or sufficient for stimulated cytoskeletal-associated actin? J. Cell. Biol. 102:1459.
52. Zigmond, S. H., J. L. Slonczewski, M. W. Wilde, and M. Carson. 1988. Polymorphonuclear leukocyte locomotion is insensitive to lowered cytoplasmic calcium levels. Cell Motil. Cytoskeleton 9:184.
53. Hendey, B., and F. R. Maxfield. 1993. Regulation of neutrophil motility and adhesion by intracellular calcium transients. Blood Cells 19:143.
54. Arai, H., C. L. Tsou, and L. F. Charo. 1997. Chemotaxis in a lymphocyte cell line transfected with C-C chemokine receptor 2B: evidence that directed migration is mediated by βγ dimers released by activation of Gαi-coupled receptors. Proc. Natl. Acad. Sci. USA 94:14495.
55. Sozzani, S., D. Zhou, M. Locati, M. Rieppi, P. Proost, M. Magazin, N. Vita, J. van Damme, and A. Mantovani. 1994. Receptors and transduclion pathways for monocyte chemotactic protein-2 and monocyte chemotactic protein-3: similarities and differences with MCP-1. 7. Immunol. 152:3615.
56. McColl, S. R., M. Hachicha, S. Levasseur, K. Neote, and T. J. Schall. 1993. Uncoupling of early signal transduction events from effector function in human peripheral blood neutrophils in response to recomhinant macrophage inflammatory proteins-1 a and -1β. J. Immunol. 150:4550.
57. Kernen, P., M. P. Wymann, V. von Tscharner, D. A. Deranleau, P. C. Tai, C. J. Spry, C. A. Dahinden, and M. Baggiolint. 1991. Shape changes, exocytosis. and cytosolic free calcium changes in stimulated human eosinophils. J. Clin. Invest. 87:2012.
58. Sivcke, J. T., and A. Hamann. 1998. T helper 1 and T helper 2 cells respond differentially to ehemokines. J. Immunol. 160:550.
59. Loetscher, P., M. Uguccioni, L. Bordoli, M. Baggiolini, B. Moser, C. Chizzolini, and J. M. Dayer. 1998. CCR5 is characteristic of Th1 lymphocytes. Nature 391: 344 (Lett.).
60. Zingoni, A., H. Soto, J. A. Hedrick, A. Stoppacciaro, C. T. Storlazzi, F. Sinigaglia, D. D'Ambrosio, A. O'Garra, D. Robinson, M. Rocchi, et al. 1998. The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells. J. Immunol. 161:547.