Opiates, psychostimulants, and adult hippocampal neurogenesis: Insights for addiction and stem cell biology

Hippocampus

Volumn 16, Issue 3, 2006, Pages 271-286

  Eisch, Amelia J ^a   Harburg, Gwyndolen C ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cell cycle; Cocaine; Dentate gyrus; Morphine; Withdrawal

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BROXURIDINE; CELL CYCLE PROTEIN; COCAINE; DIAMORPHINE; DOPAMINE; DOUBLECORTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 1BETA; METHAMPHETAMINE; MORPHINE; NERVE CELL ADHESION MOLECULE; NESTIN; OPIATE; PROSTATE SPECIFIC ANTIGEN; PROTEIN S100B; PSYCHOSTIMULANT AGENT; SOMATOMEDIN B; SOMATOMEDIN C;

ADAPTATION; ADULTHOOD; BRAIN FUNCTION; BRAIN INJURY; CELL CYCLE S PHASE; CELL FATE; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC TOXICITY; COCAINE DEPENDENCE; DENTATE GYRUS; DOPAMINERGIC SYSTEM; DRUG ABUSE; DRUG DEPENDENCE; HIPPOCAMPUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOHISTOCHEMISTRY; MORPHINE ADDICTION; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; OPIATE ADDICTION; PRIORITY JOURNAL; RELAPSE; REVIEW;

ANIMALS; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM STIMULANTS; HIPPOCAMPUS; HUMANS; NARCOTICS; NEURONAL PLASTICITY; NEURONS; STEM CELLS; SUBSTANCE-RELATED DISORDERS;

EID: 33645109259     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20161     Document Type: Review

References (214)

1. Abrous DN, Koehl M, Le Moal M. 2005. Adult neurogenesis: from precursors to network and physiology. Physiol Rev 85:523-569.
2. Amaral DG, Witter MP. 1989. The three-dimensional organization of the hippocampal formation: a review of anatomical data. Neuroscience 31:571-591.
3. Ambrogini P, Lattanzi D, Ciuffoli S, Agostini D, Bertini L, Stocchi V, Santi S, Cuppini R. 2004. Morpho-functional characterization of neuronal cells at different stages of maturation in granule cell layer of adult rat dentate gyrus. Brain Res 1017:21-31.
4. Arguello A, Norris RD, Mandyam CD, Eisch AJ. 2005. Time course of morphine's impact on hippocampal progenitor cells, growth factors, and the cell cycle. Program No. 828.5 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. (online)
5. Bahi A, Dreyer JL. 2005. Cocaine-induced expression changes of axon guidance molecules in the adult rat brain. Mol Cell Neurosci 28: 275-291.
6. Bannerman DM, Rawlins JN, McHugh SB, Deacon RM, Yee BK, Bast T, Zhang WN, Pothuizen HH, Feldon J. 2004. Regional dissociations within the hippocampus-memory and anxiety. Neurosci Biobehav Rev 28:273-283.
7. Barroso-Moguel R, Villeda-Hernandez J, Mendez-Armenta M, Rios C. 1997. Brain capillary lesions produced by cocaine in rats. Toxicol Lett 92:9-14.
8. Barroso-Moguel R, Mendez-Armenta M, Villeda-Hernandez J, Nava-Ruiz C, Santamaria A. 2002. Brain lesions induced by chronic cocaine administration to rats. Prog Neuropsychopharmacol Biol Psychiatry 26:59-63.
9. Barrot M, Olivier JD, Perrotti LI, DiLeone RJ, Berton O, Eisch AJ, Impey S, Storm DR, Neve RL, Yin JC, Zachariou V, Nestler EJ. 2002. CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc Natl Acad Sci USA 99:11435-11440.
10. Bartek J, Lukas J. 2001. Mammalian G1- and S-phase checkpoints in response to DNA damage. Curr Opin Cell Biol 13:738-747.
11. Berhow MT, Russell DS, Terwilliger RZ, Beitner-Johnson D, Self DW, Lindsay RM, Nestler EJ. 1995. Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system. Neuroscience 68:969-979.
12. Berhow MT, Hiroi N, Nestler EJ. 1996. Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine. J Neurosci 16:4707-4715.
13. Berke JD, Eichenbaum HB. 2001. Drug addiction and the hippocampus. Science 294:1235.
14. Black YD, Green-Jordan K, Eichenbaum HB, Kantak KM. 2004. Hippocampal memory system function and the regulation of cocaine self-administration behavior in rats. Behav Brain Res 151:225-238.
15. Blaha CD, Yang CR, Floresco SB, Barr AM, Phillips AG. 1997. Stimulation of the ventral subiculum of the hippocampus evokes glutamate receptor-mediated changes in dopamine efflux in the rat nucleus accumbens. Eur J Neurosci 9:902-911.
16. Blasig J, Herz A, Reinhold K, Zieglgansberger S. 1973. Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats. Psychopharmacologia 33:19-38.
17. Blumcke I, Schewe JC, Normann S, Brustle O, Schramm J, Elger CE, Wiestler OD. 2001. Increase of nestin-immunoreactive neural precursor cells in the dentate gyrus of pediatric patients with early-onset temporal lobe epilepsy. Hippocampus 11:311-321.
18. Bonfanti L, Olive S, Poulain DA, Theodosis DT. 1992. Mapping of the distribution of polysialylated neural cell adhesion molecule throughout the central nervous system of the adult rat: an immunohistochemical study. Neuroscience 49:419-436.
19. Boonstra R, Galea L, Matthews S, Wojtowicz JM. 2001. Adult neurogenesis in natural populations. Can J Physiol Pharmacol 79:297-302.
20. Borowsky B, Kuhn CM. 1991. Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation. J Pharmacol Exp Ther 256:204-210.
21. Brandt MD, Jessberger S, Steiner B, Kronenberg G, Reuter K, Bick-Sander A, von der Behrens W, Kempermann G. 2003. Transient calretinin expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice. Mol Cell Neurosci 24:603-613.
22. Buckingham JC, Cooper TA. 1984. Differences in hypothalamo-pituitary-adrenocortical activity in the rat after acute and prolonged treatment with morphine. Neuroendocrinology 38:411-417.
23. Burns KA, Kuan CY. 2005. Low doses of bromo- and iododeoxyuridine produce near-saturation labeling of adult proliferative populations in the dentate gyrus. Eur J Neurosci 21:803-807.
24. Busser J, Geldmacher DS, Herrup K. 1998. Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain. J Neurosci 18:2801-2807.
25. Cameron HA, McKay RD. 2001. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J Comp Neurol 435:406-417.
26. Cameron HA, Woolley CS, Gould E. 1993. Adrenal steroid receptor immunoreactivity in cells born in the adult rat dentate gyrus. Brain Res 611:342-346.
27. Cameron HA, Hazel TG, McKay RD. 1998. Regulation of neurogenesis by growth factors and neurotransmitters. J Neurobiol 36:287-306.
28. Castren E. 2004. Neurotrophins as mediators of drug effects on mood, addiction, and neuroprotection. Mol Neurobiol 29:289-302.
29. Caviness VS, Jr., Takahashi T, Nowakowski RS. 1999. The G1 restriction point as critical regulator of neocortical neuronogenesis. Neurochem Res 24:497-506.
30. Charara A, Grace AA. 2003. Dopamine receptor subtypes selectively modulate excitatory afferents from the hippocampus and amygdala to rat nucleus accumbens neurons. Neuropsychopharmacology 28: 1412-1421.
31. Cheng A, Wang S, Cai J, Rao MS, Mattson MP. 2003. Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain. Dev Biol 258:319-333.
32. Crespel A, Rigau V, Coubes P, Rousset MC, de Bock F, Okano H, Baldy-Moulinier M, Bockaert J, Lerner-Natoli M. 2005. Increased number of neural progenitors in human temporal lobe epilepsy. Neurobiol Dis 19:436-450.
33. Crews FT, Nixon K, Wilkie ME. 2004. Exercise reverses ethanol inhibition of neural stem cell proliferation. Alcohol 33:63-71.
34. Dawirs RR, Hildebrandt K, Teuchert-Noodt G. 1998. Adult treatment with haloperidol increases dentate granule cell proliferation in the gerbil hippocampus. J Neural Transm 105:317-327.
35. Di Chiara G. 1999. Drug addiction as dopamine-dependent associative learning disorder. Eur J Pharmacol 375:13-30.
36. Dolorfo CL, Amaral DG. 1998. Entorhinal cortex of the rat: topographic organization of the cells of origin of the perforant path projection to the dentate gyrus. J Comp Neurol 398:25-48.
37. Donovan MH, Yazdani U, Norris R, Games D, German DC, Eisch AJ. Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease. J Comp Neurol, in press.
38. Drake CT, Milner TA. 1999. Mu opioid receptors are in somatodendritic and axonal compartments of GABAergic neurons in rat hippocampal formation. Brain Res 849:203-215.
39. Drake CT, Milner TA, Patterson SL. 1999. Ultrastructural localization of full-length trkB immunoreactivity in rat hippocampus suggests multiple roles in modulating activity- dependent synaptic plasticity. J Neurosci 19:8009-8026.
40. Drake CT, Chang PC, Harris JA, Milner TA. 2002. Neurons with mu opioid receptors interact indirectly with enkephalin-containing neurons in the rat dentate gyrus. Exp Neurol 176:254-261.
41. Duman RS, Malberg J, Nakagawa S. 2001. Regulation of adult neurogenesis by psychotropic drugs and stress. J Pharmacol Exp Ther 299:401-407.
42. Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A, Zaitsev E, Gold B, Goldman D, Dean M, Lu B, Weinberger DR. 2003. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112:257-269.
43. Eisch AJ. 2002. Adult neurogenesis: implications for psychiatry. Prog Brain Res 138:315-342.
44. Eisch AJ. 2005. Common neural adaptations and bidirectional influences of stress and addiction: recent insights from basic research. J Dual Diagn 1:25-46.
45. Eisch AJ, Mandyam CD. 2004a. Beyond BrdU: basic and clinical implications for analysis of endogenous cell cycle proteins. In: Greer EV, editor. Focus on stem cell research. Nova Science. p 111-142.
46. Eisch AJ, Mandyam CD. 2004b. Drug dependence and addiction, II: adult neurogenesis and drug abuse. Am J Psychiatry 161:426.
47. Eisch AJ, Mandyam CD. 2005. Adult neurogenesis and CNS cell cycle analysis: novel tools for exploration of the neural causes and correlates of psychiatric disorders. In: Janigro D, editor. The cell cycle in the central nervous system. Totowa, NJ: Humana. p 315-342.
48. Eisch AJ, Nestler EJ. 2002. To be or not to be: adult neurogenesis and psychiatry. Clin Neurosci Res 2:93-108.
49. Eisch AJ, Barrot M, Schad CA, Self DW, Nestler EJ. 2000. Opiates inhibit neurogenesis in the adult rat hippocampus. Proc Natl Acad Sci USA 97:7579-784.
50. Emerich DF, Walsh TJ. 1989. Selective working memory impairments following intradentate injection of colchicine: attenuation of the behavioral but not the neuropathological effects by gangliosides GM1 and AGF2. Physiol Behav 45:93-101.
51. Emerich DF, Walsh TJ. 1990. Hyperactivity following intradentate injection of colchicine: a role for dopamine systems in the nucleus accumbens. Pharmacol Biochem Behav 37:149-154.
52. Everitt BJ, Dickinson A, Robbins TW. 2001. The neuropsychological basis of addictive behaviour. Brain Res Brain Res Rev 36:129-138.
53. Ferbinteanu J, Holsinger RM, McDonald RJ. 1999. Lesions of the medial or lateral perforant path have different effects on hippocampal contributions to place learning and on fear conditioning to context. Behav Brain Res 101:65-84.
54. Filippov V, Kronenberg G, Pivneva T, Reuter K, Steiner B, Wang LP, Yamaguchi M, Kettenmann H, Kempermann G. 2003. Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes. Mol Cell Neurosci 23:373-382.
55. Floresco SB, Blaha CD, Yang CR, Phillips AG. 2001a. Modulation of hippocampal and amygdalar-evoked activity of nucleus accumbens neurons by dopamine: cellular mechanisms of input selection. J Neurosci 21:2851-2860.
56. Floresco SB, Todd CL, Grace AA. 2001b. Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons. J Neurosci 21:4915-4922.
57. Ford HL, Pardee AB. 1998. The S phase: beginning, middle, and end: a perspective. J Cell Biochem Suppl 30/31:1-7.
58. Freeman WM, Brebner K, Amara SG, Reed MS, Pohl J, Phillips AG. 2005. Distinct proteomic profiles of amphetamine self-administration transitional states. Pharmacogenomics J 5:203-214.
59. Fuchs RA, Evans KA, Ledford CC, Parker MP, Case JM, Mehra RH, See RE. 2005. The role of the dorsomedial prefrontal cortex, basolateral amygdala, and dorsal hippocampus in contextual reinstatement of cocaine seeking in rats. Neuropsychopharmacology 30: 296-309.
60. Fujise N, Liu Y, Hori N, Kosaka T. 1998. Distribution of calretinin immunoreactivity in the mouse dentate gyrus: II. Mossy cells, with special reference to their dorsoventral difference in calretinin immunoreactivity. Neuroscience 82:181-200.
61. Fukuda S, Kato F, Tozuka Y, Yamaguchi M, Miyamoto Y, Hisatsune T. 2003. Two distinct subpopulations of nestin-positive cells in adult mouse dentate gyrus. J Neurosci 23:9357-9366.
62. Fukuda A, Fukuda H, Swanpalmer J, Hertzman S, Lannering B, Marky I, Bjork-Eriksson T, Blomgren K. 2005. Age-dependent sensitivity of the developing brain to irradiation is correlated with the number and vulnerability of progenitor cells. J Neurochem 92: 569-584.
63. Galici R, Pechnick RN, Poland RE, France CP. 2000. Comparison of noncontingent versus contingent cocaine administration on plasma corticosterone levels in rats. Eur J Pharmacol 387:59-62.
64. Garcia A, Steiner B, Kronenberg G, Bick-Sander A, Kempermann G. 2004a. Age-dependent expression of glucocorticoid- and mineralocorticoid receptors on neural precursor cell populations in the adult murine hippocampus. Aging Cell 3:363-371.
65. Garcia AD, Doan NB, Imura T, Bush TG, Sofroniew MV. 2004b. GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat Neurosci 7:1233-1241.
66. Garcia ADR, Imura T, Bush TG, Sofroniew MV. 2001. Neurogenesis is decreased following ablation of dividing, GFAP-positive radial astrocytes in the hippocampus of adult transgenic mice. Program No. 894.10 Abstract Viewer and Itinerary Planner. San Diego, CA: Society for Neuroscience, 2001. (online)
67. Gasbarri A, Campana E, Pacitti C, Hajdu F, Tombol T. 1991. Organization of the projections from the ventral tegmental area of Tsai to the hippocampal formation in the rat. J Hirnforsch 32:429-437.
68. Gasbarri A, Verney C, Innocenzi R, Campana E, Pacitti C. 1994. Mesolimbic dopaminergic neurons innervating the hippocampal formation in the rat: a combined retrograde tracing and immunohistochemical study. Brain Res 668:71-79.
69. GENSAT. 2005. The gene expression nervous system atlas project at Rockefeller University. New York, NY: NINDS. Contract No. N01NS02331.
70. Goeders NE. 2002. The HPA axis and cocaine reinforcement. Psychoneuroendocrinology 27:13-33.
71. Goldsmith SK, Joyce JN. 1994. Dopamine D2 receptor expression in hippocampus and parahippocampal cortex of rat, cat, and human in relation to tyrosine hydroxylase-immunoreactive fibers. Hippocampus 4:354-373.
72. Gottifredi V, Prives C. 2005. The S phase checkpoint: when the crowd meets at the fork. Semin Cell Dev Biol 16:355-368.
73. Gould E, Tanapat P. 1999. Stress and hippocampal neurogenesis. Biol Psychiatry 46:1472-1479.
74. Gould E, Beylin A, Tanapat P, Reeves A, Shots TJ. 1999. Learning enhances adult neurogenesis in the hippocampal formation. Nat Neurosci 2:260-265.
75. Grimm JW, Lu L, Hayashi T, Hope BT, Su TP, Shaham Y. 2003. Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving. J Neurosci 23:742-747.
76. Groenewegen HJ, Vermeulen-Van der Zee E, te Kortschot A, Witter MP. 1987. Organization of the projections from the subiculum to the ventral striatum in the rat. A study using anterograde transport of Phaseolus vulgaris leucoagglutinin. Neuroscience 23:103-120.
77. Gurok U, Steinhoff C, Lipkowitz B, Ropers HH, Scharff C, Nuber UA. 2004. Gene expression changes in the course of neural progenitor cell differentiation. J Neurosci 24:5982-6002.
78. Hall FS, Drgonova J, Goeb M, Uhl GR. 2003. Reduced behavioral effects of cocaine in heterozygous brain-derived neurotrophic factor (BDNF) knockout mice. Neuropsychopharmacology 28:1485-1490.
79. Hammer RP Jr, Ricalde AA, Seatriz JV. 1989. Effects of opiates on brain development. Neurotoxicology 10:475-483.
80. Harburg GC, Hall FS, Harrist AV, Sora I, Uhl GR, Eisch AJ. 2005. Knock-out of the mu opioid receptor enhances survival of progenitor cells in the adult hippocampus. Program No. 595.14 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. (online)
81. Harvey JA. 2004. Cocaine effects on the developing brain: current status. Neurosci Biobehav Rev 27:751-764.
82. Hayes NL, Nowakowski RS. 2002. Dynamics of cell proliferation in the adult dentate gyrus of two inbred strains of mice. Brain Res Dev Brain Res 134:77-85.
83. Heidbreder CA, Hagan JJ. 2005. Novel pharmacotherapeutic approaches for the treatment of drug addiction and craving. Curr Opin Pharmacol 5:107-118.
84. Heine VM, Maslam S, Joels M, Lucassen PJ. 2004. Increased P27KIP1 protein expression in the dentate gyrus of chronically stressed rats indicates G1 arrest involvement. Neuroscience 129:593-601.
85. Hildebrandt K, Teuchert-Noodt G, Dawirs RR. 1999. A single neonatal dose of methamphetamine suppresses dentate granule cell proliferation in adult gerbils which is restored to control values by acute doses of haloperidol. J Neural Transm 106:549-558.
86. Hoglinger GU, Rizk P, Muriel MP, Duyckaerts C, Oertel WH, Caille I, Hirsch EC. 2004. Dopamine depletion impairs precursor cell proliferation in Parkinson disease. Nat Neurosci 7:726-735.
87. Horger BA, Iyasere CA, Berhow MT, Messer CJ, Nestler EJ, Taylor JR. 1999. Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. J Neurosci 19:4110-4122.
88. Hortnagl H, Berger ML, Sperk G, Pifl C. 1991. Regional heterogeneity in the distribution of neurotransmitter markers in the rat hippocampus. Neuroscience 45:261-272.
89. Houser CR. 1990. Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy. Brain Res 535:195-204.
90. Imperato A, Obinu MC, Casu MA, Mascia MS, Carta G, Gessa GL. 1996. Chronic morphine increases hippocampal acetylcholine release: possible relevance in drug dependence. Eur J Pharmacol 302: 21-26.
91. Jacobs BL, Praag H, Gage FH. 2000. Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol Psychiatry 5:262-269.
92. Jin K, Peel AL, Mao XO, Xie L, Cottrell BA, Henshall DC, Greenberg DA. 2004. Increased hippocampal neurogenesis in Alzheimer's disease. Proc Natl Acad Sci USA 101:343-347.
93. Jordan-Sciutto K, Rhodes J, Bowerr R. 2001. Altered subcellular distribution of transcriptional regulators in response to Abeta peptide and during Alzheimer's disease. Mech Ageing Dev 123:11-20.
94. Jordan-Sciutto KL, Malaiyandi LM, Bowser R. 2002. Altered distribution of cell cycle transcriptional regulators during Alzheimer disease. J Neuropath Exp Neurol 61:358-367.
95. Jordan-Sciutto KL, Dorsey R, Chalovich EM, Hammond RR, Achim CL. 2003. Expression patterns of retinoblastoma protein in Parkinson disease. J Neuropath Exp Neurol 62:68-74.
96. Kahn L, Alonso G, Normand E, Manzoni OJ. 2005. Repeated morphine treatment alters polysialylated neural cell adhesion molecule, glutamate decarboxylase-67 expression and cell proliferation in the adult rat hippocampus. Eur J Neurosci 21:493-500.
97. Kalivas PW, Pierce RC, Cornish J, Sorg BA. 1998. A role for sensitization in craving and relapse in cocaine addiction. J Psychopharmacol 12:49-53.
98. Kalivas PW, McFarland K, Bowers S, Szumlinski K, Xi ZX, Baker D. 2003. Glutamate transmission and addiction to cocaine. Ann N Y Acad Sci 1003:169-175.
99. Kantak KM, Udo T, Ugalde F, Luzzo C, Di Pietro N, Eichenbaum HB. 2005. Influence of cocaine self-administration on learning related to prefrontal cortex or hippocampus functioning in rats. Psychopharmacology (Berl) 181:227-236.
100. Kastan MB, Bartek J. 2004. Cell-cycle checkpoints and cancer. Nature 432:316-323.
101. Katou Y, Kanoh Y, Bando M, Noguchi H, Tanaka H, Ashikari T, Sugimoto K, Shirahige K. 2003. S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex. Nature 424: 1078-1083.
102. Kee N, Sivalingam S, Boonstra R, Wojtowicz JM. 2002. The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis. J Neurosci Methods 115:97-105.
103. Kelley AE, Domesick VB. 1982. The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: an anterograde- and retrograde-horseradish peroxidase study. Neuroscience 7:2321-2335.
104. Kempermann G, Kuhn HG, Gage FH. 1998. Experience-induced neurogenesis in the senescent dentate gyrus. J Neurosci 18:3206-3212.
105. Kempermann G, Gast D, Kronenberg G, Yamaguchi M, Gage FH. 2003. Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development 130:391-399.
106. Kempermann G, Jessberger S, Steiner B, Kronenberg G. 2004. Milestones of neuronal development in the adult hippocampus. Trends Neurosci 27:447-452.
107. Kolb B, Gorny G, Li Y, Samaha AN, Robinson TE. 2003. Amphetamine or cocaine limits the ability of later experience to promote structural plasticity in the neocortex and nucleus accumbens. Proc Natl Acad Sci USA 100:10523-10528.
108. Koob GF. 1992. Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends Pharmacol Sci 13:177-184.
109. Koob GF, Nestler EJ. 1997. The neurobiology of drug addiction. J Neuropsychiatry Clin Neurosci 9:482-497.
110. Koob GF, Maldonado R, Stinus L. 1992. Neural substrates of opiate withdrawal. Trends Neurosci 15:186-191.
111. Koob GF, Ahmed SH, Boutrel B, Chen SA, Kenny PJ, Markou A, O'Dell LE, Parsons LH, Sanna PP. 2004. Neurobiological mechanisms in the transition from drug use to drug dependence. Neurosci Biobehav Rev 27:739-749.
112. Kreek MJ. 2001. Drug addictions. Molecular and cellular endpoints. Ann N Y Acad Sci 937:27-49.
113. Kronenberg G, Reuter K, Steiner B, Brandt MD, Jessberger S, Yamaguchi M, Kempermann G. 2003. Subpopulations of proliferating cells of the adult hippocampus respond differently to physiologic neurogenic stimuli. J Comp Neurol 467:455-463.
114. Lagace DC, Farnbauch L, Eisch AJ. 2005. High throughput assessment of proliferation of newly born cells in the adult hippocampus. Program No. 143.11 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. (online)
115. Lein ES, Zhao X, Gage FH. 2004. Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization. J Neurosci 24:3879-3889.
116. Lein ES, Callaway EM, Albright TD, Gage FH. 2005. Redefining the boundaries of the hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional reconstruction. J Comp Neurol 485:1-10.
117. Li Y, Kolb B, Robinson TE. 2005. Psychostimulant drugs alter the effect of complex housing on synpatic plasticity and CA1 pyramidal neurons. Program No. 1032.4 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. (online)
118. London M. 2005. History of addiction: a UK perspective. Am J Addict 14:97-105.
119. Lu L, Dempsey J, Liu SY, Bossert JM, Shaham Y. 2004a. A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. J Neurosci 24:1604-1611.
120. Lu L, Grimm JW, Hope BT, Shaham Y. 2004b. Incubation of cocaine craving after withdrawal: a review of preclinical data. Neuropharmacology (Suppl 47) 1:214-26.
121. Mackowiak M, Markowicz-Kula K, Fijal K, Wedzony K. 2005. Acute and repeated administration of cocaine differentially regulates expression of PSA-NCAM-positive neurons in the rat hippocampus. Brain Res 1055:149-155.
122. Majewska MD. 2002. HPA axis and stimulant dependence: an enigmatic relationship. Psychoneuroendocrinology 27:5-12.
123. Makiura Y, Suzuki F, Chevalier E, Onteniente B. 1999. Excitatory granule cells of the dentate gyrus exhibit a double inhibitory neurochemical content after intrahippocampal administration of kainate in adult mice. Exp Neurol 159:73-83.
124. Malberg JE, Eisch AJ, Nestler EJ, Duman RS. 2000. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20:9104-9110.
125. Mandyam CD, Eisch AJ. 2004. Chronic morphine alters the pro-proliferative environment in the adult rodent hippocampus. Program No. 357.16 Abstract Viewer and Itinerary Planner. San Diego, CA: Society for Neuroscience, 2004. (online)
126. Mandyam CD, Norris RD, Eisch AJ. 2004. Chronic morphine induces premature mitosis of proliferating cells in the adult mouse subgranular zone. J Neurosci Res 76:783-794.
127. Mantsch JR, Goeders NE. 2000. Effects of cocaine self-administration on plasma corticosterone in rats: relationship to hippocampal type II glucocorticoid receptors. Prog Neuropsychopharmacol Biol Psychiatry 24:633-646.
128. Mao L, Wang JQ. 2001. Gliogenesis in the striatum of the adult rat: alteration in neural progenitor population after psychostimulant exposure. Brain Res Dev Brain Res 130:41-51.
129. Mattson MP, Maudsley S, Martin B. 2004. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends Neurosci 27:589-594.
130. Mayo W, Le Moal M, Abrous DN. 2001. Pregnenolone sulfate and aging of cognitive functions: behavioral, neurochemical, and morphological investigations. Horm Behav 40:215-217.
131. McGowan CH. 2002. Checking in on Cds1 (Chk2): a checkpoint kinase and tumor suppressor. Bioessays 24:502-511.
132. Milner TA, Bacon CE. 1989. Ultrastructural localization of tyrosine hydroxylase-like immunoreactivity in the rat hippocampal formation. J Comp Neurol 281:479-495.
133. Mitchell ES, Snyder-Kelley A. 2003. Blockade of D1 dopaminergic transmission alleviates c-fos induction and cleaved caspase-3 expression in the brains of rat pups exposed to prenatal cocaine or perinatal asphyxia. Exp Neurol 182:64-74.
134. Mitchell SN, Yee BK, Feldon J, Gray JA, Rawlins JN. 2000. Activation of the retrohippocampal region in the rat causes dopamine release in the nucleus accumbens: disruption by fornix section. Eur J Pharmacol 407:131-138.
135. Mogenson GJ, Nielsen M. 1984. A study of the contribution of hippocampal-accumbens-subpallidal projections to locomotor activity. Behav Neural Biol 42:38-51.
136. Moldow RL, Fischman AJ. 1987. Cocaine induced secretion of ACTH, beta-endorphin, and corticosterone. Peptides 8:819-822.
137. Montaron MF, Piazza PV, Aurousseau C, Urani A, Le Moal M, Abrous DN. 2003. Implication of corticosteroid receptors in the regulation of hippocampal structural plasticity. Eur J Neurosci 18: 3105-3111.
138. Naber PA, Witter MP. 1998. Subicular efferents are organized mostly as parallel projections: a double-labeling, retrograde-tracing study in the rat. J Comp Neurol 393:284-297.
139. Nacher J, Palop JJ, Ramirez C, Molowny A, Lopez-Garcia C. 2000a. Early histological maturation in the hippocampus of the guinea pig. Brain Behav Evol 56:38-44.
140. Nacher J, Rosell DR, McEwen BS. 2000b. Widespread expression of rat collapsin response-mediated protein 4 in the telencephalon and other areas of the adult rat central nervous system. J Comp Neurol 424:628-639.
141. Nacher J, Crespo C, McEwen BS. 2001. Doublecortin expression in the adult rat telencephalon. Eur J Neurosci 14:629-644.
142. Nagy Z, Esiri MM, Cato AM, Smith AD. 1997a. Cell cycle markers in the hippocampus in Alzheimer's disease. Acta Neuropathol (Berl) 94:6-15.
143. Nagy Z, Esiri MM, Smith AD. 1997b. Expression of cell division markers in the hippocampus in Alzheimer's disease and other neurodegenerative conditions. Acta Neuropathol (Berl) 93:294-300.
144. Nassogne MC, Louahed J, Evrard P, Courtoy PJ. 1997. Cocaine induces apoptosis in cortical neurons of fetal mice. J Neurochem 68: 2442-2450.
145. Neisewander JL, Baker DA, Fuchs RA, Tran-Nguyen LT, Palmer A, Marshall JF. 2000. Fos protein expression and cocaine-seeking behavior in rats after exposure to a cocaine self-administration environment. J Neurosci 20:798-805.
146. Nestler EJ. 2001a. Molecular basis of long-term plasticity underlying addiction. Nat Rev Neurosci 2:119-128.
147. Nestler EJ. 2001b. Neurobiology. Total recall-the memory of addiction. Science 292:2266-2267.
148. Nestler EJ. 2002. Common molecular and cellular substrates of addiction and memory. Neurobiol Learn Mem 78:637-647.
149. Nibuya M, Morinobu S, Duman RS. 1995. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci 15:7539-7547.
150. Nixon K, Crews FT. 2004. Temporally specific burst in cell proliferation increases hippocampal neurogenesis in protracted abstinence from alcohol. J Neurosci 24:9714-9722.
151. Nock B, Wich M, Cicero TJ. 1997. Chronic exposure to morphine increases corticosteroid-binding globulin. J Pharmacol Exp Ther 282:1262-1268.
152. Novikova SI, He F, Bai J, Badan I, Lidow IA, Lidow MS. 2005. Cocaine-induced changes in the expression of apoptosis-related genes in the fetal mouse cerebral wall. Neurotoxicol Teratol 27:3-14.
153. Nowakowski RS, Lewin SB, Miller MW. 1989. Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population. J Neurocytol 18:311-318.
154. Ohtani N, Goto T, Waeber C, Bhide PG. 2003. Dopamine modulates cell cycle in the lateral ganglionic eminence. J Neurosci 23:2840-2850.
155. Okano HJ, Pfaff DW, Gibbs RB. 1993. RB and Cdc2 expression in brain: correlations with 3H-thymidine incorporation and neurogenesis. J Neurosci 13:2930-2938.
156. Okano HJ, Pfaff DW, Gibbs RB. 1996. Expression of EGFR-, p75NGFR-, and PSTAIR (cdc2)-like immunoreactivity by proliferating cells in the adult rat hippocampal formation and forebrain. Dev Neurosci 18:199-209.
157. Oliveira MT, Rego AC, Macedo TR, Oliveira CR. 2003. Drugs of abuse induce apoptotic features in PC12 cells. Ann N Y Acad Sci 1010:667-670.
158. Osztrogonacz MA, Choi KH, Norris RD, Eisch AJ. 2005. Chronic cocaine self-administration decreases proliferation, and withdrawal increase adult hippocampal neurogenesis. Program No. 828.6 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. (online)
159. Overstreet LS, Hentges ST, Bumaschny VF, de Souza FS, Smart JL, Santangelo AM, Low MJ, Westbrook GL, Rubinstein M. 2004. A transgenic marker for newly born granule cells in dentate gyrus. J Neurosci 24:3251-3259.
160. Panikkar GP. 1999. Cocaine addiction: neurobiology and related current research in pharmacotherapy. Subst Abus 20:149-166.
161. Parent JM. 2002. The role of seizure-induced neurogenesis in epileptogenesis and brain repair. Epilepsy Res 50:179-189.
162. Parent JM, Lowenstein DH. 2002. Seizure-induced neurogenesis: are more new neurons good for an adult brain? Prog Brain Res 135: 121-131.
163. Patel NA, Romero AA, Zadina JE, Chang SL. 1996. Chronic exposure to morphine attenuates expression of interleukin-1 beta in the rat hippocampas. Brain Res 712:340-344.
164. Pechnick RN. 1993. Effects of opioids on the hypothalamo-pituitary-adrenal axis. Annu Rev Pharmacol Toxicol 33:353-382.
165. Pelchat ML, Johnson A, Chan R, Valdez J, Ragland JD. 2004. Images of desire: food-craving activation during fMRI. Neuroimage 23: 1486-1493.
166. Pierce RC, Pierce-Bancroft AF, Prasad BM. 1999. Neurotrophin-3 contributes to the initiation of behavioral sensitization to cocaine by activating the Ras/Mitogen-activated protein kinase signal transduction cascade. J Neurosci 19:8685-8695.
167. Rao MS, Shetty AK. 2004. Efficacy of doublecortin as a marker to analyse the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus: Eur J Neurosci 19:234-246.
168. Russo-Neustadt A. 2003. Brain-derived neurotrophic factor, behavior, and new directions for the treatment of mental disorders. Semin Clin Neuropsychiatry 8:109-118.
169. Sairanen M, Lucas G, Ernfors P, Castren M, Castren E. 2005. Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J Neurosci 25:1089-1094.
170. Sakakibara S, Imai T, Hamaguchi K, Okabe M, Aruga J, Nakajima K, Yasutomi D, Nagata T, Kurihara Y, Uesugi S, Miyata T, Ogawa M, Mikoshiba K, Okano H. 1996. Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell. Dev Biol 176:230-242.
171. Scharfman HE, Goodman JH, Sollas AL. 2000. Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: functional implications of seizure-induced neurogenesis. J Neurosci 20:6144-6158.
172. Self DW. 1998. Neural substrates of drug craving and relapse in drug addiction. Ann Med 30:379-389.
173. Self DW, Choi KH. 2004. Extinction-induced neuroplasticity attenuates stress-induced cocaine seeking: a state-dependent learning hypothesis. Stress 7:145-155.
174. Self DW, Choi KH, Simmons D, Walker JR, Smagula CS. 2004.
175. Seri B, Garcia-Verdugo JM, McEwen BS, Alvarez-Buylla A. 2001. Astrocytes give rise to new neurons in the adult mammalian hippocampus. J Neurosci 21:7153-7160.
176. Seri B, Garcia-Verdugo JM, Collado-Morente L, McEwen BS, Alvarez-Buylla A. 2004. Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus. J Comp Neurol 478:359-378.
177. Shors TJ, Townsend DA, Zhao M, Kozorovitskiy Y, Gould E. 2002. Neurogenesis may relate to some but not all types of hippocampal-dependent learning. Hippocampus 12:578-584.
178. Sofuoglu M, Kosten TR. 2005. Novel approaches to the treatment of cocaine addiction. CNS Drugs 19:13-25.
179. Spain JW, Newsom GC. 1991. Chronic opioids impair acquisition of both radial maze and Y-maze choice escape. Psychopharmacology 105:101-106.
180. Spanagel R, Weiss F. 1999. The dopamine hypothesis of reward: past and current status. Trends Neurosci 22:521-527.
181. Stiene-Martin A, Knapp PE, Martin K, Gurwell JA, Ryan S, Thornton SR, Smith FL, Hauser KF. 2001. Opioid system diversity in developing neurons, astroglia, and oligodendroglia in the subventricular zone and striatum: impact on gliogenesis in vivo. Glia 36:78-88.
182. Sun W, Rebec GV. 2003. Lidocaine inactivation of ventral subiculum attenuates cocaine-seeking behavior in rats. J Neurosci 23:10258-10264.
183. Sundholm-Peters NL, Yang HK, Goings GE, Walker AS, Szele FG. 2004. Radial glia-like cells at the base of the lateral ventricles in adult mice. J Neurocytol 33:153-164.
184. Taepavarapruk P, Floresco SB, Phillips AG. 2000. Hyperlocomotion and increased dopamine efflux in the rat nucleus accumbens evoked by electrical stimulation of the ventral subiculum: role of ionotropic glutamate and dopamine D1 receptors. Psychopharmacology (Berl) 151:242-251.
185. Tegeder I, Geisslinger G. 2004. Opioids as modulators of cell death and survival-unraveling mechanisms and revealing new indications. Pharmacol Rev 56:351-369.
186. Teuchert-Noodt G, Dawirs RR, Hildebrandt K. 2000. Adult treatment with methamphetamine transiently decreases dentate granule cell proliferation in the gerbil hippocampus. J Neural Transm 107: 133-143.
187. Totterdell S, Smith AD. 1989. Convergence of hippocampal and dopaminergic input onto identified neurons in the nucleus accumbens of the rat. J Chem Neuroanat 2:285-298.
188. van Praag H, Schinder AF, Christie BR, Toni N, Palmer TD, Gage FH. 2002. Functional neurogenesis in the adult hippocampus. Nature 415:1030-1034.
189. Vega CJ, Peterson DA. 2005. Stem cell proliferative history in tissue revealed by temporal halogenated thymidine analog discrimination. Nat Methods 2:167-169.
190. Verney C, Baulac M, Berger B, Alvarez C, Vigny A, Helle KB. 1985. Morphological evidence for a dopaminergic terminal field in the hippocampal formation of young and adult rat. Neuroscience 14: 1039-1052.
191. Vorel SR, Liu X, Hayes RJ, Spector JA, Gardner EL. 2001. Relapse to cocaine-seeking after hippocampal theta burst stimulation. Science 292:1175-1178.
192. Walsh TJ, Emerich DF, Schmechel DE. 1989. GM1 ganglioside attenuates the behavioral deficits but not the granule cell damage produced by intradentate colchicine. Brain Res 478:24-33.
193. Wamsley JK, Gehlert DR, Filloux FM, Dawson TM. 1989. Comparison of the distribution of D-1 and D-2 dopamine receptors in the rat brain. J Chem Neuroanat 2:119-137.
194. Wang J, Charboneau R, Balasubramanian S, Barke RA, Loh HH, Roy S. 2002. The immunosuppressive effects of chronic morphine treatment are partially dependent on corticosterone and mediated by the mu-opioid receptor. J Leukoc Biol 71:782-790.
195. Weickert CS, Webster MJ, Colvin SM, Herman MM, Hyde TM, Weinberger DR, Kleinman JE. 2000. Localization of epidermal growth factor receptors and putative neuroblasts in human subependymal zone. J Comp Neurol 423:359-372.
196. Weiss F. 2005. Neurobiology of craving, conditioned reward and relapse. Curr Opin Pharmacol 5:9-19.
197. Weiss F, Ciccocioppo R, Parsons LH, Katner S, Liu X, Zorrilla EP, Valdez GR, Ben-Shahar O, Angeletti S, Richter RR. 2001. Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors. Ann N Y Acad Sci 937:1-26.
198. White FJ, Kalivas PW. 1998. Neuroadaptations involved in amphetamine and cocaine addiction. Drug Alcohol Depend 51:141-153.
199. White NM. 1996. Addictive drugs as reinforcers: multiple partial actions on memory systems. Addiction 91:921-949 (discussion 951-965).
200. Won M, Minabe Y, Tani K, Suzuki K, Kawai M, Sekine Y, Ashby CR, Jr., Takei N, Mori N. 2003. The effects of dentate granule cell destruction on behavioral activity and Fos protein expression induced by systemic MDMA in rats. Neurosci Res 46:153-160.
201. Yamaguchi M, Saito H, Suzuki M, Mori K. 2000. Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice. Neuroreport 11:1991-1996.
202. Yamaguchi M, Suzuki T, Seki T, Namba T, Juan R, Arai H, Hori T, Asada T. 2004. Repetitive cocaine administration decreases neurogenesis in adult rat hippocampus. Ann N Y Acad Sci 1025:351-362.
203. Yamaguchi M, Suzuki T, Seki T, Namba T, Liu J, Arai H, Hori T, Shiga T. 2005. Decreased cell proliferation in the dentate gyrus of rats after repeated administration of cocaine. Synapse 58:63-71.
204. Yan Q, Radeke MJ, Matheson CR, Talvenheimo J, Welcher AA, Feinstein SC. 1997. Immunocytochemical localization of TrkB in the central nervous system of the adult rat. J Comp Neurol 378:135-157.
205. Yang CR, Mogenson GJ. 1987. Hippocampal signal transmission to the pedunculopontine nucleus and its regulation by dopamine D2 receptors in the nucleus accumbens: an electrophysiological and behavioural study. Neuroscience 23:1041-1055.
206. Yang HK, Sundholm-Peters NL, Goings GE, Walker AS, Hyland K, Szele FG. 2004. Distribution of doublecortin expressing cells near the lateral ventricles in the adult mouse brain. J Neurosci Res 76: 282-295.
207. Yang Y, Geldmacher DS, Herrup K. 2001. DNA replication precedes neuronal cell death in Alzheimer's disease. J Neurosci 21:2661-2668.
208. Yang Y, Mufson EJ, Herrup K. 2003. Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease. J Neurosci 23:2557-2563.
209. Yu TS, Dandekar M, Monteggia LM, Parada LF, Kernie SG. 2005. Temporally regulated expression of Cre recombinase in neural stem cells. Genesis 41:147-153.
210. Zachor D, Cherkes JK, Fay CT, Ocrant I. 1994. Cocaine differentially inhibits neuronal differentiation and proliferation in vitro. J Clin Invest 93(3):1179-1185.
211. Zhang D, Zhang L, Tang Y, Zhang Q, Lou D, Sharp FR, Zhang J, Xu M. 2005. Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors. Neuropsychopharmacology 30:1443-1454.
212. Zhang L, Xiao Y, He J. 1999. Cocaine and apoptosis in myocardial cells. Anat Rec 257:208-216.
213. Zornoza T, Cano-Cebrian MJ, Martinez-Garcia F, Polache A, Granero L. 2005a. Hippocampal dopamine receptors modulate cFos expression in the rat nucleus accumbens evoked by chemical stimulation of the ventral hippocampus. Neuropharmacology 49:1067-1076.
214. Zornoza T, Cano-Cebrian MJ, Miquel M, Aragon C, Polache A, Granero L. 2005b. Hippocampal dopamine receptors modulate the motor activation and the increase in dopamine levels in the rat nucleus accumbens evoked by chemical stimulation of the ventral hippocampus. Neuropsychopharmacology 30:843-852.