Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine

Journal of Neuroscience

Volumn 16, Issue 15, 1996, Pages 4707-4715

  Berhow, Melissa T ^a   Hiroi, Noboru ^a   Nestler, Eric J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

antisense oligonucleotides; BDNF; cocaine; ERK; morphine; NMDA glutamate receptors; tyrosine hydroxylase; ventral tegmental area

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; BRAIN DERIVED NEUROTROPHIC FACTOR; COCAINE; GLUTAMATE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROTROPHIN; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; DRUG ABUSE; DRUG EXPOSURE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IMMUNOREACTIVITY; MALE; MESOLIMBIC DOPAMINERGIC SYSTEM; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; VENTRAL TEGMENTUM;

EID: 0029954749     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-15-04707.1996     Document Type: Article

References (46)

1. Beitner-Johnson D, Nestler EJ (1991) Morphine and cocaine exert common chronic actions on tyrosine hydroxylase in dopaminergic brain reward regions. J Neurochem 57:344-347.
2. Beitner-Johnson D, Guitart X, Nestler EJ (1992) Neurofilament proteins and the mesolimbic dopamine system: common regulation by chronic morphine and chronic cocaine in the rat ventral tegmental area. J Neurosci 12:2165-2176.
3. Berhow MT, Russell DS, Terwilliger RZ, Beitner-Johnson D, Self DS, Lindsay RM, Nestler EJ (1995) Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system. Neuroscience 68:969-979.
4. Berhow MT, Hiroi N, Kobierski LA, Hyman SE, Nestler EJ (1996) Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. Soc Neurosci Abstr, in press.
5. Boulton TG, Yancopoulos GD, Gregory JS, Slaughter C, Moomaw C, Hsu J, Cobb MH (1990) An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control. Science 249:64-67.
6. Bozarth MA, Wise RA (1986) Involvement of the ventral tegmental dopamine system in opioid and psychomotor stimulant reinforcement. In: Problems of drug dependence (Harris LS, ed), pp 190-196. Washington, D.C.: US Government Printing Office.
7. Davis RJ (1993) The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268:14553-14556.
8. Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ (1994) JNK1: a protein kinase stimulated by UV light and Ha-ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037.
9. Fitzgerald LW, Ortiz J, Hamedani AG, Nestler EJ (1996) Regulation of glutamate receptor subunit expression by drugs of abuse and stress: common adaptations among cross-sensitizing agents. J Neurosci 16:274-282.
10. Gardner AM, Vaillancourt RR, Johnson GL (1993) Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins. J Biol Chem 268:17896-17901.
11. Ghosh A, Greenberg ME (1995) Calcium signalling in neurons: molecular mechanisms and cellular consequences. Science 268:239-247.
12. Gizang-Ginsberg E, Ziff EB (1990) Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos. Genes Dev 4:477-491.
13. Guitart X, Nestler EJ (1989) Identification of morphine- and cyclic AMP-regulated phosphoproteins (MARPPs) in the locus coeruleus and other regions of rat brain: regulation by acute and chronic morphine. J Neurosci 9:2649-2659.
14. Haycock JW, Ahn NG, Cobb MH, Krebs EG (1992) ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. Proc Natl Acad Sci USA 89:2365-2369.
15. Henry DJ, Greene MA, White FJ (1989) Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: repeated administration. J Pharmacol Exp Ther 251:833-839.
16. Hu BR, Wieloch T (1994) Tyrosine phosphorylation and activation of mitogen-activated protein kinase in the rat brain following transient cerebral ischemia. J Neurochem 62:1357-1367.
17. Hurd YL, Linefors N, Brodin E, Brené S, Persson H, Ungerstedt U, Hökfelt T (1992) Amphetamine regulation of mesolimbic dopamine/ cholecystokinin neurotransmission. Brain Res 578:317-326.
18. Jay TM, Burette F, Laroche S (1995) NMDA receptor-dependent long term potentiation in the hippocampal afferent fibre system to the prefrontal cortex in the rat. Eur J Neurosci 7:247-250.
19. Kameshita I, Fujiscua H (1989) A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel. Anal Biochem 183:139-143.
20. Karler R, Chaudhry IA, Calder LD, Turkanis SA (1991) DNQX blockade of amphetamine behavioral sensitization. Brain Res 552:295-300.
21. Kogan JH, Aghajanian GK (1995) Long-term desensitization in locus coeruleus neurons and its role in opiate withdrawal. Brain Res 689:111-121.
22. Koob GF (1992) Drugs of abuse: anatomy, pharmacology, and function of reward pathways. Trends Pharmacol Sci 13:177-184.
23. Kuhar MJ, Ritz MC, Boja JW (1991) The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci 14:299-302.
24. Lewis SE, Rao MS, Symes AJ, Daurer WT, Fink JS, Landis SC, Hyman SE (1994) Coordinated regulation of choline acetyltransferase, tyrosine hydroxylase, and neuropeptide m RNAs by ciliary neurotrophic factor and leukemia inhibitory factor in cultured sympathetic neurons. J Neurochem 63:429-438.
25. Minden A, Lin A, McMahon M, Lange-Carter C, Derijard B, Davis RJ, Johnson GL, Karin M (1994a) Differential activation of ERK and JNK mitogen-activated protein kinases by raf-1 and MEKK. Science 266:1719-1723.
26. Minden A, Lin A, Smeal T, Derijard B, Cobb M, Davis R, Karin M (1994b) c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases. Mol Cell Biol 14:6683-6688.
27. Nestler EJ (1992) Molecular mechanisms of drug addiction. J Neurosci 12:2439-2450.
28. 3H]D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience 26:17-31.
29. Ortiz J, Fitzgerald LW, Charlton M, Lane S, Trevisan L, Guitart X, Shoemaker W, Duman RS, Nestler EJ (1995a) Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system. Synapse 21:289-298.
30. Ortiz J, Harris HW, Guitart X, Terwilliger RZ, Haycock JW, Nestler EJ (1995b) Extracellular signal-regulated protein kinase (ERKs) and ERK kinase (MEK) in brain: regional distribution and regulation by chronic morphine. J Neurosci 15:1285-1297.
31. Rabinovsky ED, Ramchatesingh J, McManaman JL (1995) Regulation of tyrosine hydroxylase gene expression in 1MR-32 neuroblastoma cells by basic fibroblast growth factor and ciliary neurotrophic factor. J Neurochem 64:2404-2412.
32. Robbins DJ, Zhen E, Owaki H, Vanderbilt CA, Ebert D, Geppert TD, Cobb MH (1993) Regulation and properties of extracellular signalregulated protein kinases 1 and 2 in vitro. J Biol Chem 268:5097-5106.
33. Russell DS, Berhow MT, Widnell KL, Self DW, Nestler EJ (1994) Modulation of neurotrophin receptor tyrosine kinase (RTK) pathways in the mesolimbic dopamine system by drugs of abuse. Soc Neurosci Abstr 20:1102.
34. Schenk S, Valadez A, McNamara C, House DT, Higley D, Bankson MG, Giggs S, Horger BA (1993) Development and expression of sensitization to cocaine's reinforcing properties: role of NMDA receptors. Psychopharmacology 11:332-338.
35. Seger R, Krebs EG (1995) The MAPK signaling cascade. FASEB J 9:726-735.
36. Self DW, Nestler EJ (1995) Molecular mechanisms of drug reinforcement and addiction. Annu Rev Neurosci 18:463-495.
37. Sorg BA, Chen S-Y, Kalivas PW (1993) Time of tyrosine hydroxylase expression after behavioral sensitization to cocaine. J Pharmacol Exp Ther 266:424-430.
38. Stein CA, Cheng YC (1993) Antisense oligonucleotides as therapeutic agents - Is the bullet really magical? Science 261:1004-1012.
39. Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y (1994) JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77:727-736.
40. Taber MT, Das S, Fibiger HC (1995) Cortical regulation of subcortical dopamine release: mediation via the ventral tegmental area. J Neurochem 65:1407-1410.
41. Vrana SL, Vrana KE, Koves TR, Smith JE, Dworkin SI (1993) Chronic cocaine administration increases CNS tyrosine hydroxylase enzyme activity and mRNA levels and tryptophan hydroxylase enzyme activity. J Neurochem 61:2262-2268.
42. Westwick JK, Weitzel C, Minden A, Karin M, Brenner DA (1994) Tumor necrosis factor a stimulates AP-1 through prolonged activation of the c-Jun kinase. J Biol Chem 269:26396-26401.
43. White FJ, Hu XT, Zhang XF, Wolf ME (1995) Repeated administration of cocaine or amphetamine alters neuronal responses to glutamate in the mesoaccumbens dopamine system. J Pharmacol Exp Ther 273:445-454.
44. Whitton PS, Richards DA, Biggs CS, Fowler LJ (1994) N-methyl-D-aspartate receptors modulate extracellular 5-hydroxytryptamine concentration in rat hippocampus and striatum in vivo. Neurosci Lett 169:215-218.
45. Widnell KL, Self DW, Russell DS, Lane S, Vaidya V, Nestler EJ (1996) Regulation of expression of cAMP response element binding protein (CREB) in the nucleus accumbens: a functional role for CREB down-regulation by morphine. J Pharmacol Exp Ther 276:306-315.
46. Wolf ME, White FJ, Hu XT (1994) MK-801 prevents alterations in the mesoaccumbens dopamine system associated with behavioral sensitization to amphetamine. J Neurosci 14:1735-1745.