메뉴 건너뛰기




Volumn 11, Issue 2 P.1199-1590, 2006, Pages 1360-1370

Dendritic cells and CD4+CD25+ T regulatory cells: Crosstalk between two professionals in immunity versus tolerance

Author keywords

Anergy; CD4+CD25+ Treg; CTLA 4; Cytokine; DCs; Foxp3; GITR; IL 10; IL 6; Indoleamine 2,3 dioxygenase; Review; TGF

Indexed keywords


EID: 32844469349     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/1889     Document Type: Review
Times cited : (65)

References (89)
  • 2
    • 0141742297 scopus 로고    scopus 로고
    • Some interfaces of dendritic cell biology
    • Steinman, R. M. Some interfaces of dendritic cell biology. Apmis 111:675-697 (2003)
    • (2003) Apmis , vol.111 , pp. 675-697
    • Steinman, R.M.1
  • 4
    • 0033584234 scopus 로고    scopus 로고
    • Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells
    • Iwasaki, A., and B. L. Kelsall. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J Exp Med 190:229-239 (1999)
    • (1999) J Exp Med , vol.190 , pp. 229-239
    • Iwasaki, A.1    Kelsall, B.L.2
  • 5
    • 0034960320 scopus 로고    scopus 로고
    • TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu
    • Chen, W., M. E. Frank, W. Jin, and S. M. Wahl. TGF-beta Released by Apoptotic T Cells Contributes to an Immunosuppressive Milieu. Immunity 14:715-725 (2001)
    • (2001) Immunity , vol.14 , pp. 715-725
    • Chen, W.1    Frank, M.E.2    Jin, W.3    Wahl, S.M.4
  • 6
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok, V. A., D. L. Bratton, A. Konowal, P. W. Freed, J. Y. Westcott, and P. M. Henson. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 101:890-898 (1998)
    • (1998) J Clin Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 7
    • 0034613767 scopus 로고    scopus 로고
    • Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • Jonuleit, H., E. Schmitt, G. Schuler, J. Knop, and A. H. Enk. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 192:1213-1222 (2000)
    • (2000) J Exp Med , vol.192 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.H.5
  • 9
    • 17644372733 scopus 로고    scopus 로고
    • IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
    • Liu, Y. J. IPC: Professional Type 1 Interferon-Producing Cells and Plasmacytoid Dendritic Cell Precursors. Annu Rev Immunol 23:275-306 (2005)
    • (2005) Annu Rev Immunol , vol.23 , pp. 275-306
    • Liu, Y.J.1
  • 11
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi, S., N. Sakaguchi, M. Asano, M. Itoh, and M. Toda. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155:1151-1164 (1995)
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 12
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4 (+)CD25 (+) regulatory T cells
    • Fontenot, J. D., M. A. Gavin, and A. Y. Rudensky. Foxp3 programs the development and function of CD4 (+)CD25 (+) regulatory T cells. Nat Immunol 4:330-336 (2003)
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 14
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4 (+)CD25 (+) T regulatory cells
    • Khattri, R., T. Cox, S. A. Yasayko, and F. Ramsdell. An essential role for Scurfin in CD4 (+)CD25 (+) T regulatory cells. Nat Immunol 4:337-342 (2003)
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 15
    • 0035806289 scopus 로고    scopus 로고
    • Certified professionals: CD4 (+)CD25 (+) suppressor T cells
    • Shevach, E. M. Certified professionals: CD4 (+)CD25 (+) suppressor T cells. J Exp Med 193:F41-46 (2001)
    • (2001) J Exp Med , vol.193
    • Shevach, E.M.1
  • 16
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi, S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101:455-458 (2000)
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 17
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25 (+)CD4 (+) regulatory T cells through GITR breaks immunological self-tolerance
    • Shimizu, J., S. Yamazaki, T. Takahashi, Y. Ishida, and S. Sakaguchi. Stimulation of CD25 (+)CD4 (+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 3:135-142 (2002)
    • (2002) Nat Immunol , vol.3 , pp. 135-142
    • Shimizu, J.1    Yamazaki, S.2    Takahashi, T.3    Ishida, Y.4    Sakaguchi, S.5
  • 18
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More questions than answers
    • + suppressor T cells: more questions than answers. Nat Rev Immunol 2:389-400 (2002)
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 19
    • 0041806547 scopus 로고    scopus 로고
    • In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro
    • Klein, L., K. Khazaie, and H. Von Boehmer. In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro. Proc Natl Acad Sci U S A 100:8886-8891 (2003)
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8886-8891
    • Klein, L.1    Khazaie, K.2    Von Boehmer, H.3
  • 21
    • 2142818492 scopus 로고    scopus 로고
    • + regulatory T cells: Implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance
    • + regulatory T cells: implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance. Novartis Found Symp 252:6-16 (2003)
    • (2003) Novartis Found Symp , vol.252 , pp. 6-16
    • Sakaguchi, S.1    Hori, S.2    Fukui, Y.3    Sasazuki, T.4    Sakaguchi, N.5    Takahashi, T.6
  • 22
    • 0037450746 scopus 로고    scopus 로고
    • + regulatory T cells that express toll-like receptors
    • + regulatory T cells that express toll-like receptors. J Exp Med 197:397-401 (2003)
    • (2003) J Exp Med , vol.197 , pp. 397-401
    • Sakaguchi, S.1
  • 24
    • 0037099733 scopus 로고    scopus 로고
    • Human CD4 (+)CD25 (+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells
    • Dieckmann, D., C. H. Bruett, H. Ploetmer, M. B. Lutz, and G. Schuler. Human CD4 (+)CD25 (+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. J Exp Med 196:247-253 (2002)
    • (2002) J Exp Med , vol.196 , pp. 247-253
    • Dieckmann, D.1    Bruett, C.H.2    Ploetmer, H.3    Lutz, M.B.4    Schuler, G.5
  • 26
    • 2442425262 scopus 로고    scopus 로고
    • Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants
    • Cobbold, S. P., R. Castejon, E. Adams, D. Zelenika, L. Graca, S. Humm, and H. Waldmann. Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J Immunol 172:6003-6010 (2004)
    • (2004) J Immunol , vol.172 , pp. 6003-6010
    • Cobbold, S.P.1    Castejon, R.2    Adams, E.3    Zelenika, D.4    Graca, L.5    Humm, S.6    Waldmann, H.7
  • 29
    • 1342267617 scopus 로고    scopus 로고
    • + T cells in peripheral blood of patients with systemic lupus erythematosus
    • + T cells in peripheral blood of patients with systemic lupus erythematosus. Scand J Immunol 59:198-202 (2004)
    • (2004) Scand J Immunol , vol.59 , pp. 198-202
    • Liu, M.F.1    Wang, C.R.2    Fung, L.L.3    Wu, C.R.4
  • 30
    • 17844376787 scopus 로고    scopus 로고
    • + regulatory T cells for the treatment of inflammatory bowel diseases
    • + regulatory T cells for the treatment of inflammatory bowel diseases. Expert Opin Biol Ther 5:451-462 (2005)
    • (2005) Expert Opin Biol Ther , vol.5 , pp. 451-462
    • Kanai, T.1    Watanabe, M.2
  • 33
    • 0036569127 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation
    • Woo, E. Y., H. Yeh, C. S. Chu, K. Schlienger, R. G. Carroll, J. L. Riley, L. R. Kaiser, and C. H. June. Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation. J Immunol 168:4272-4276 (2002)
    • (2002) J Immunol , vol.168 , pp. 4272-4276
    • Woo, E.Y.1    Yeh, H.2    Chu, C.S.3    Schlienger, K.4    Carroll, R.G.5    Riley, J.L.6    Kaiser, L.R.7    June, C.H.8
  • 34
    • 22144487400 scopus 로고    scopus 로고
    • CD4 (+)CD25 (+) regulatory T cells in HIV infection
    • Nixon, D. F., E. M. Aandahl, and J. Michaelsson. CD4 (+)CD25 (+) regulatory T cells in HIV infection. Microbes Infect 7:1063-1065 (2005)
    • (2005) Microbes Infect , vol.7 , pp. 1063-1065
    • Nixon, D.F.1    Aandahl, E.M.2    Michaelsson, J.3
  • 37
    • 5644302161 scopus 로고    scopus 로고
    • Human T regulatory cells can use the perform pathway to cause autologous target cell death
    • Grossman, W. J., J. W. Verbsky, W. Barchet, M. Colonna, J. P. Atkinson, and T. J. Ley., Human T regulatory cells can use the perform pathway to cause autologous target cell death. Immunity 21:589-601 (2004)
    • (2004) Immunity , vol.21 , pp. 589-601
    • Grossman, W.J.1    Verbsky, J.W.2    Barchet, W.3    Colonna, M.4    Atkinson, J.P.5    Ley, T.J.6
  • 38
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 188:287-296 (1998)
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 40
    • 0036195161 scopus 로고    scopus 로고
    • CD4 (+)CD25 (+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh, R. S., M. J. Whitters, C. A. Piccirillo, D. A. Young, E. M. Shevach, M. Collins, and M. C. Byrne. CD4 (+)CD25 (+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid- induced TNF receptor. Immunity 16:311-323 (2002)
    • (2002) Immunity , vol.16 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3    Young, D.A.4    Shevach, E.M.5    Collins, M.6    Byrne, M.C.7
  • 43
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25 (+)CD4 (+) regulatory cells that control intestinal inflammation
    • Read, S., V. Malmstrom, and F. Powrie. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25 (+)CD4 (+) regulatory cells that control intestinal inflammation. J Exp Med 192:295-302 (2000)
    • (2000) J Exp Med , vol.192 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 44
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi, T., T. Tagami, S. Yamazaki, T. Uede, J. Shimizu, N. Sakaguchi, T. W. Mak, and S. Sakaguchi. Immunologic self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 192:303-310 (2000)
    • (2000) J Exp Med , vol.192 , pp. 303-310
    • Takahashi, T.1    Tagami, T.2    Yamazaki, S.3    Uede, T.4    Shimizu, J.5    Sakaguchi, N.6    Mak, T.W.7    Sakaguchi, S.8
  • 45
    • 0037379654 scopus 로고    scopus 로고
    • TGF-beta: The missing link in CD4 (+)CD25 (+) regulatory T cell-mediated immunosuppression
    • Chen, W., and S. M. Wahl. TGF-beta: the missing link in CD4 (+)CD25 (+) regulatory T cell-mediated immunosuppression. Cytokine Growth Factor Rev 14:85-89 (2003)
    • (2003) Cytokine Growth Factor Rev , vol.14 , pp. 85-89
    • Chen, W.1    Wahl, S.M.2
  • 46
    • 0347994958 scopus 로고    scopus 로고
    • B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions
    • Taylor, P. A., C. J. Lees, S. Fournier, J. P. Allison, A. H. Sharpe, and B. R. Blazar. B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions [corrections]. J Immunol 172:34-39 (2004)
    • (2004) J Immunol , vol.172 , pp. 34-39
    • Taylor, P.A.1    Lees, C.J.2    Fournier, S.3    Allison, J.P.4    Sharpe, A.H.5    Blazar, B.R.6
  • 47
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer, H. Mechanisms of suppression by suppressor T cells. Nat Immunol 6:338-344 (2005)
    • (2005) Nat Immunol , vol.6 , pp. 338-344
    • Von Boehmer, H.1
  • 48
    • 0035801335 scopus 로고    scopus 로고
    • Cell contact-dependent immunosuppression by CD4 (+)CD25 (+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura, K., A. Kitani, and W. Strober. Cell contact-dependent immunosuppression by CD4 (+)CD25 (+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med 194:629-644 (2001)
    • (2001) J Exp Med , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 51
    • 0036358166 scopus 로고    scopus 로고
    • TGF-beta: Receptors, signaling pathways and autoimmunity
    • Chen, W., and S. M. Wahl. TGF-beta: receptors, signaling pathways and autoimmunity. Curr Dir Autoimmun 5:62-91 (2002)
    • (2002) Curr Dir Autoimmun , vol.5 , pp. 62-91
    • Chen, W.1    Wahl, S.M.2
  • 53
    • 0022465625 scopus 로고
    • Production of transforming growth factor □ by human T lymphocytes and its potential role in the regulation of T cell growth
    • Kehrl, J. H., L. M. Wakefield, A. B. Roberts, S. Jakowelw, M. Alvarez-Mon, R. Derynck, M. B. Sporn, and A. S. Fauci. Production of transforming growth factor □ by human T lymphocytes and its potential role in the regulation of T cell growth. J. Exp. Med 163:1037-1050 (1986)
    • (1986) J. Exp. Med , vol.163 , pp. 1037-1050
    • Kehrl, J.H.1    Wakefield, L.M.2    Roberts, A.B.3    Jakowelw, S.4    Alvarez-Mon, M.5    Derynck, R.6    Sporn, M.B.7    Fauci, A.S.8
  • 54
    • 15444363794 scopus 로고    scopus 로고
    • T cells that cannot respond to TGF-beta escape control by CD4 (+)CD25 (+) regulatory T cells
    • Fahlen, L., S. Read, L. Gorelik, S. D. Hurst, R. L. Coffman, R. A. Flavell, and F. Powrie. T cells that cannot respond to TGF-beta escape control by CD4 (+)CD25 (+) regulatory T cells. J Exp Med 201:737-746 (2005)
    • (2005) J Exp Med , vol.201 , pp. 737-746
    • Fahlen, L.1    Read, S.2    Gorelik, L.3    Hurst, S.D.4    Coffman, R.L.5    Flavell, R.A.6    Powrie, F.7
  • 56
    • 0141703239 scopus 로고    scopus 로고
    • + T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes
    • + T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes. Proc Natl Acad Sci U S A 100:10878-10883 (2003)
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10878-10883
    • Green, E.A.1    Gorelik, L.2    McGregor, C.M.3    Tran, E.H.4    Flavell, R.A.5
  • 58
    • 17044430217 scopus 로고    scopus 로고
    • Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
    • Wan, Y. Y., and R. A. Flavell. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc Natl Acad Sci U S A 102:5126-5131 (2005)
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5126-5131
    • Wan, Y.Y.1    Flavell, R.A.2
  • 59
    • 0037148511 scopus 로고    scopus 로고
    • Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
    • McGuirk, P., C. McCann, and K. H. Mills. Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J Exp Med 195:221-231 (2002)
    • (2002) J Exp Med , vol.195 , pp. 221-231
    • McGuirk, P.1    McCann, C.2    Mills, K.H.3
  • 60
    • 0037987977 scopus 로고    scopus 로고
    • Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
    • Wakkach, A., N. Fournier, V. Brun, J. P. Breittmayer, F. Cottrez, and H. Groux. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18:605-617 (2003)
    • (2003) Immunity , vol.18 , pp. 605-617
    • Wakkach, A.1    Fournier, N.2    Brun, V.3    Breittmayer, J.P.4    Cottrez, F.5    Groux, H.6
  • 62
    • 0037240852 scopus 로고    scopus 로고
    • Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10
    • Martin, E., B. O'Sullivan, P. Low, and R. Thomas. Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10. Immunity 18:155-167 (2003)
    • (2003) Immunity , vol.18 , pp. 155-167
    • Martin, E.1    O'Sullivan, B.2    Low, P.3    Thomas, R.4
  • 63
    • 4644297765 scopus 로고    scopus 로고
    • Antisense oligonucleotides down-regulating costimulation confer diabetes-preventive properties to nonobese diabetic mouse dendritic cells
    • Machen, J., J. Harnaha, R. Lakomy, A. Styche, M. Trucco, and N. Giannoukakis. Antisense oligonucleotides down-regulating costimulation confer diabetes-preventive properties to nonobese diabetic mouse dendritic cells. J Immunol 173:4331-4341 (2004)
    • (2004) J Immunol , vol.173 , pp. 4331-4341
    • Machen, J.1    Harnaha, J.2    Lakomy, R.3    Styche, A.4    Trucco, M.5    Giannoukakis, N.6
  • 65
    • 0038792101 scopus 로고    scopus 로고
    • + regulatory T cells by targeting of antigens to immature dendritic cells
    • + regulatory T cells by targeting of antigens to immature dendritic cells. Blood 101:4862-4869 (2003)
    • (2003) Blood , vol.101 , pp. 4862-4869
    • Mahnke, K.1    Qian, Y.2    Knop, J.3    Enk, A.H.4
  • 66
    • 0037302966 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases
    • Adorini, L., G. Penna, N. Giarratana, and M. Uskokovic. Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases. J Cell Biochem 88:227-233 (2003)
    • (2003) J Cell Biochem , vol.88 , pp. 227-233
    • Adorini, L.1    Penna, G.2    Giarratana, N.3    Uskokovic, M.4
  • 67
    • 18944379171 scopus 로고    scopus 로고
    • + regulatory T cells play a critical role in granulocyte-macrophage colony-stimulating factor-induced suppression of experimental autoimmune thyroiditis
    • + regulatory T cells play a critical role in granulocyte-macrophage colony-stimulating factor-induced suppression of experimental autoimmune thyroiditis. J Immunol 174:7006-7013 (2005)
    • (2005) J Immunol , vol.174 , pp. 7006-7013
    • Gangi, E.1    Vasu, C.2    Cheatem, D.3    Prabhakar, B.S.4
  • 68
    • 12144270876 scopus 로고    scopus 로고
    • Treatment with granulocyte colony-stimulating factor prevents diabetes in NOD mice by recruiting plasmacytoid dendritic cells and functional CD4 (+)CD25 (+) regulatory T-cells
    • Kared, H., A. Masson, H. Adle-Biassette, J. F. Bach, L. Chatenoud, and F. Zavala. Treatment with granulocyte colony-stimulating factor prevents diabetes in NOD mice by recruiting plasmacytoid dendritic cells and functional CD4 (+)CD25 (+) regulatory T-cells. Diabetes 54:78-84 (2005)
    • (2005) Diabetes , vol.54 , pp. 78-84
    • Kared, H.1    Masson, A.2    Adle-Biassette, H.3    Bach, J.F.4    Chatenoud, L.5    Zavala, F.6
  • 70
    • 0037301566 scopus 로고    scopus 로고
    • A central role for peripheral dendritic cells in the induction of acquired thymic tolerance
    • Goldschneider, I., and R. E. Cone. A central role for peripheral dendritic cells in the induction of acquired thymic tolerance. Trends Immunol 24:77-81 (2003)
    • (2003) Trends Immunol , vol.24 , pp. 77-81
    • Goldschneider, I.1    Cone, R.E.2
  • 72
    • 9244223651 scopus 로고    scopus 로고
    • Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity
    • Stock, P., O. Akbari, G. Berry, G. J. Freeman, R. H. Dekruyff, and D. T. Umetsu. Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nat Immunol 5:1149-1156 (2004)
    • (2004) Nat Immunol , vol.5 , pp. 1149-1156
    • Stock, P.1    Akbari, O.2    Berry, G.3    Freeman, G.J.4    Dekruyff, R.H.5    Umetsu, D.T.6
  • 73
    • 0033233252 scopus 로고    scopus 로고
    • TGF-beta1 regulation of dendritic cells
    • Strobl, H., and W. Knapp. TGF-beta1 regulation of dendritic cells. Microbes Infect 1:1283-1290 (1999)
    • (1999) Microbes Infect , vol.1 , pp. 1283-1290
    • Strobl, H.1    Knapp, W.2
  • 74
    • 10844252294 scopus 로고    scopus 로고
    • + regulatory cell activation and function by dendritic cells
    • + regulatory cell activation and function by dendritic cells. Int Immunol 16:1769-1780 (2004)
    • (2004) Int Immunol , vol.16 , pp. 1769-1780
    • Fehervari, Z.1    Sakaguchi, S.2
  • 75
    • 0037099719 scopus 로고    scopus 로고
    • Infectious tolerance: Human CD25 (+) regulatory T cells convey suppressor activity to conventional CD4 (+) T helper cells
    • Jonuleit, H., E. Schmitt, H. Kakirman, M. Stassen, J. Knop, and A. H. Enk. Infectious tolerance: human CD25 (+) regulatory T cells convey suppressor activity to conventional CD4 (+) T helper cells. J Exp Med 196:255-260 (2002)
    • (2002) J Exp Med , vol.196 , pp. 255-260
    • Jonuleit, H.1    Schmitt, E.2    Kakirman, H.3    Stassen, M.4    Knop, J.5    Enk, A.H.6
  • 76
    • 0037436119 scopus 로고    scopus 로고
    • + T cell-mediated suppression by dendritic cells
    • + T Cell-Mediated Suppression by Dendritic Cells. Science 299:1033-1036 (2003)
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 78
    • 0034077559 scopus 로고    scopus 로고
    • + regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
    • + regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur J Immunol 30:1538-1543 (2000)
    • (2000) Eur J Immunol , vol.30 , pp. 1538-1543
    • Cederbom, L.1    Hall, H.2    Ivars, F.3
  • 81
    • 3142519564 scopus 로고    scopus 로고
    • In vitro-expanded human CD4 (+)CD25 (+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures
    • Godfrey, W. R., Y. G. Ge, D. J. Spoden, B. L. Levine, C. H. June, B. R. Blazar, and S. B. Porter. In vitro-expanded human CD4 (+)CD25 (+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures. Blood 104:453-461 (2004)
    • (2004) Blood , vol.104 , pp. 453-461
    • Godfrey, W.R.1    Ge, Y.G.2    Spoden, D.J.3    Levine, B.L.4    June, C.H.5    Blazar, B.R.6    Porter, S.B.7
  • 82
    • 31644438853 scopus 로고    scopus 로고
    • Maturation of circulating dendritic cells and imbalance of T-cell subsets in patients with squamous cell carcinoma of the head and neck
    • May 12 [Epub ahead of print]
    • Sakakura, K., K. Chikamatsu, K. Takahashi, T. L. Whiteside, and N. Furuya. Maturation of circulating dendritic cells and imbalance of T-cell subsets in patients with squamous cell carcinoma of the head and neck. Cancer Immunol Immunother May 12 [Epub ahead of print] (2005)
    • (2005) Cancer Immunol Immunother
    • Sakakura, K.1    Chikamatsu, K.2    Takahashi, K.3    Whiteside, T.L.4    Furuya, N.5
  • 85
    • 16244399547 scopus 로고    scopus 로고
    • CD4 (+)CD25 high regulatory T cells in human pregnancy
    • Saito, S., Y. Sasaki, and M. Sakai. CD4 (+)CD25high regulatory T cells in human pregnancy. J Reprod Immunol 65:111-120 (2005)
    • (2005) J Reprod Immunol , vol.65 , pp. 111-120
    • Saito, S.1    Sasaki, Y.2    Sakai, M.3
  • 86
    • 0034770605 scopus 로고    scopus 로고
    • Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells
    • Gorelik, L., and R. A. Flavell. Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells. Nat Med 7:1118-1122 (2001)
    • (2001) Nat Med , vol.7 , pp. 1118-1122
    • Gorelik, L.1    Flavell, R.A.2
  • 87
    • 0030456368 scopus 로고    scopus 로고
    • A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: The skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells
    • Borkowski, T. A., J. J. Letterio, A. G. Farr, and M. C. Udey. A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells. J Exp Med 184:2417-2422 (1996)
    • (1996) J Exp Med , vol.184 , pp. 2417-2422
    • Borkowski, T.A.1    Letterio, J.J.2    Farr, A.G.3    Udey, M.C.4
  • 89
    • 0025092082 scopus 로고
    • Transcription and expression of transforming growth factor type beta in the skin of progressive systemic sclerosis: A mediator of fibrosis?
    • Gruschwitz, M., P. U. Muller, N. Sepp, E. Hofer, A. Fontana, and G. Wick. Transcription and expression of transforming growth factor type beta in the skin of progressive systemic sclerosis: a mediator of fibrosis? J Invest Dermatol 94:197-203 (1990)
    • (1990) J Invest Dermatol , vol.94 , pp. 197-203
    • Gruschwitz, M.1    Muller, P.U.2    Sepp, N.3    Hofer, E.4    Fontana, A.5    Wick, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.