메뉴 건너뛰기




Volumn 88, Issue 2, 2003, Pages 227-233

Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases

Author keywords

Immunoregulation; Regulatory T cells; Tolerance; Vitamin D analogues

Indexed keywords

1,25 DIHYDROXY 16,23 DIENE 26,27 HEXAFLUORO 19 NOR VITAMIN D3; AUTOANTIGEN; B7 ANTIGEN; BXL 698; CALCITRIOL; CALCITRIOL DERIVATIVE; CD4 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2 RECEPTOR; LIGAND; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

EID: 0037302966     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10340     Document Type: Conference Paper
Times cited : (223)

References (41)
  • 1
    • 0035135215 scopus 로고    scopus 로고
    • Interleukin 12 and autoimmune diabetes
    • Adorini L. 2001. Interleukin 12 and autoimmune diabetes. Nat Genet 27:131-132.
    • (2001) Nat Genet , vol.27 , pp. 131-132
    • Adorini, L.1
  • 2
    • 0029918886 scopus 로고    scopus 로고
    • Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF)
    • Allison AC, Eugui EM. 1996: Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF). Clin Transplant 10:77-84.
    • (1996) Clin Transplant , vol.10 , pp. 77-84
    • Allison, A.C.1    Eugui, E.M.2
  • 3
    • 0029149894 scopus 로고
    • Transcriptional repression of the interleukin-2 gene by vitamin D3: Direct inhibition NFATp/AP-1 complex formation by a nuclear hormone receptor
    • Alroy I, Towers T, Freedman L. 1995. Transcriptional repression of the interleukin-2 gene by vitamin D3: Direct inhibition NFATp/AP-1 complex formation by a nuclear hormone receptor. Mol Cell Biol 15:5789-5799.
    • (1995) Mol Cell Biol , vol.15 , pp. 5789-5799
    • Alroy, I.1    Towers, T.2    Freedman, L.3
  • 4
    • 0033001488 scopus 로고    scopus 로고
    • The NOD mouse model of type 1 diabetes: As good as it gets?
    • Atkinson MA, Leiter EH. 1999. The NOD mouse model of type 1 diabetes: As good as it gets? Nat Med 5:601-604.
    • (1999) Nat Med , vol.5 , pp. 601-604
    • Atkinson, M.A.1    Leiter, E.H.2
  • 5
    • 0037018104 scopus 로고    scopus 로고
    • In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, de Waal-Malefyt R, Coffman RL, Hawrylowicz CM, O'Garra A. 2002. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 195:603-616.
    • (2002) J Exp Med , vol.195 , pp. 603-616
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3    Richards, D.F.4    Crain, C.5    Savelkoul, H.F.6    De Waal-Malefyt, R.7    Coffman, R.L.8    Hawrylowicz, C.M.9    O'Garra, A.10
  • 6
    • 0030890588 scopus 로고    scopus 로고
    • Cell death mediators in autoimmune diabetes - No shortage of suspects
    • Benoist C, Mathis D. 1997. Cell death mediators in autoimmune diabetes - No shortage of suspects. Cell 89:1-3.
    • (1997) Cell , vol.89 , pp. 1-3
    • Benoist, C.1    Mathis, D.2
  • 8
    • 0035497752 scopus 로고    scopus 로고
    • 1Alpha,25-dihydroxyvitamin D3 has a direct effect on naive CD4+ T cells to enhance the development of Th2 cells
    • Boonstra A, Barrat FJ, Crain C, Heath VL, Savelkoul HF, O'Garra A. 2001. 1alpha,25-Dihydroxyvitamin D3 has a direct effect on naive CD4+ T cells to enhance the development of Th2 cells. J Immunol 167:4974-4980.
    • (2001) J Immunol , vol.167 , pp. 4974-4980
    • Boonstra, A.1    Barrat, F.J.2    Crain, C.3    Heath, V.L.4    Savelkoul, H.F.5    O'Garra, A.6
  • 9
    • 0034852081 scopus 로고    scopus 로고
    • 1-Alpha,25-dihydroxyvitamin D3 (1,25(OH)(2)D(3)) hampers the maturation of fully active immature dendritic cells from monocytes
    • Canning MO, Grotenhuis K, de Wit H, Ruwhof C, Drexhage HA. 2001. 1-alpha,25-Dihydroxyvitamin D3 (1,25(OH)(2)D(3)) hampers the maturation of fully active immature dendritic cells from monocytes. Eur J Endocrinol 145:351-357.
    • (2001) Eur J Endocrinol , vol.145 , pp. 351-357
    • Canning, M.O.1    Grotenhuis, K.2    De Wit, H.3    Ruwhof, C.4    Drexhage, H.A.5
  • 10
    • 0032525285 scopus 로고    scopus 로고
    • Prevention of autoimmune destruction of syngeneic islet grafts in spontaneously diabetic nonobese diabetic mice by a combination of a vitamin D3 analog and cyclosporine
    • Casteels K, Waer M, Laureys J, Valckx D, Depovere J, Bouillon R, Mathieu C. 1998a. Prevention of autoimmune destruction of syngeneic islet grafts in spontaneously diabetic nonobese diabetic mice by a combination of a vitamin D3 analog and cyclosporine. Transplantation 65: 1225-1232.
    • (1998) Transplantation , vol.65 , pp. 1225-1232
    • Casteels, K.1    Waer, M.2    Laureys, J.3    Valckx, D.4    Depovere, J.5    Bouillon, R.6    Mathieu, C.7
  • 11
    • 0031747106 scopus 로고    scopus 로고
    • Sex difference in resistance to dexamethasone-induced apoptosis in NOD mice: Treatment with 1,25(OH)2D3 restores defect
    • Casteels KM, Gysemans CA, Waer M, Bouillon R, Laureys JM, Depovere J, Mathieu C. 1998b. Sex difference in resistance to dexamethasone-induced apoptosis in NOD mice: Treatment with 1,25(OH)2D3 restores defect. Diabetes 47:1033-1037.
    • (1998) Diabetes , vol.47 , pp. 1033-1037
    • Casteels, K.M.1    Gysemans, C.A.2    Waer, M.3    Bouillon, R.4    Laureys, J.M.5    Depovere, J.6    Mathieu, C.7
  • 12
    • 0034038972 scopus 로고    scopus 로고
    • Vitamin D receptor gene polymorphisms influence susceptibility to type 1 diabetes mellitus in the Taiwanese population
    • Chang TJ, Lei HH, Yeh JI, Chiu KC, Lee KC, Chen MC, Tai TY, Chuang LM. 2000. Vitamin D receptor gene polymorphisms influence susceptibility to type 1 diabetes mellitus in the Taiwanese population. Clin Endocrinol 52:575-580.
    • (2000) Clin Endocrinol , vol.52 , pp. 575-580
    • Chang, T.J.1    Lei, H.H.2    Yeh, J.I.3    Chiu, K.C.4    Lee, K.C.5    Chen, M.C.6    Tai, T.Y.7    Chuang, L.M.8
  • 13
    • 0031595992 scopus 로고    scopus 로고
    • Vitamin D3: A transcriptional modulator of the IFN-ygene
    • Cippitelli M, Santoni A. 1998. Vitamin D3: A transcriptional modulator of the IFN-ygene. Eur J Immunol. 28: 3017-3030.
    • (1998) Eur J Immunol , vol.28 , pp. 3017-3030
    • Cippitelli, M.1    Santoni, A.2
  • 14
    • 0031974910 scopus 로고    scopus 로고
    • Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene
    • D'Ambrosio D, Cippitelli M, Cocciolo MG, Mazzeo D, Di Lucia P, Lang R, Sinigaglia F, Panina-Bordignon P. 1998. Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene. J Clin Invest 101: 252-262.
    • (1998) J Clin Invest , vol.101 , pp. 252-262
    • D'Ambrosio, D.1    Cippitelli, M.2    Cocciolo, M.G.3    Mazzeo, D.4    Di Lucia, P.5    Lang, R.6    Sinigaglia, F.7    Panina-Bordignon, P.8
  • 15
    • 0031423760 scopus 로고    scopus 로고
    • The non-obese diabetic mouse as a model of autoimmune diabetes: Immune dysregulation gets the NOD
    • Delovitch TL, Singh B. 1997. The non-obese diabetic mouse as a model of autoimmune diabetes: Immune dysregulation gets the NOD. Immunity 7:727-738.
    • (1997) Immunity , vol.7 , pp. 727-738
    • Delovitch, T.L.1    Singh, B.2
  • 16
    • 0026562971 scopus 로고
    • Incidence of childhood-onset insulin-dependent diabetes mellitus: The EURODIAB ACE Study
    • Green A, Gale EA, Patterson CC. 1992. Incidence of childhood-onset insulin-dependent diabetes mellitus: The EURODIAB ACE Study. Lancet 339:905-909.
    • (1992) Lancet , vol.339 , pp. 905-909
    • Green, A.1    Gale, E.A.2    Patterson, C.C.3
  • 17
    • 0036020679 scopus 로고    scopus 로고
    • A 1α,25-dihydroxyvitamin D3 analog enhances regulatory T cells and arrests autoimmune diabetes in NOD mice
    • Gregori G, Giarratana N, Smiroldo S, Uskokovic M, Adorini L 2002: A 1α,25-Dihydroxyvitamin D3 analog enhances regulatory T cells and arrests autoimmune diabetes in NOD mice. Diabetes 51:1367-1374.
    • (2002) Diabetes , vol.51 , pp. 1367-1374
    • Gregori, G.1    Giarratana, N.2    Smiroldo, S.3    Uskokovic, M.4    Adorini, L.5
  • 18
    • 0035881234 scopus 로고    scopus 로고
    • Regulatory T cells induced by 1α,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance
    • Gregori S, Casorati M, Amuchastegui S, Smiroldo S, Davalli AM, Adorini L 2001: Regulatory T cells induced by 1α,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 167:1945-1953.
    • (2001) J Immunol , vol.167 , pp. 1945-1953
    • Gregori, S.1    Casorati, M.2    Amuchastegui, S.3    Smiroldo, S.4    Davalli, A.M.5    Adorini, L.6
  • 19
    • 0000026481 scopus 로고    scopus 로고
    • Dendritic cell modulation by lalpha,25 dihydroxyvitamin D3 and its analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo
    • Griffin MD, Lutz W, Phan VA, Bachman LA, McKean DJ, Kumar R. 2001. Dendritic cell modulation by lalpha,25 dihydroxyvitamin D3 and its analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo. Proc Natl Acad Sci USA 22:22.
    • (2001) Proc Natl Acad Sci USA , vol.22 , pp. 22
    • Griffin, M.D.1    Lutz, W.2    Phan, V.A.3    Bachman, L.A.4    McKean, D.J.5    Kumar, R.6
  • 23
    • 0034613767 scopus 로고    scopus 로고
    • Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • Jonuleit H, Schmitt E, Schuler G, Knop J, Enk AH. 2000. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 192:1213-1222.
    • (2000) J Exp Med , vol.192 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.H.5
  • 24
    • 0029018309 scopus 로고
    • Immunosuppressive actions of 1,25-dihydroxyvitamin D3: Preferential inhibition of Th1 functions
    • Lemire JM, Archer DC, Beck L, Spiegelberg HL. 1995. Immunosuppressive actions of 1,25-dihydroxyvitamin D3: Preferential inhibition of Th1 functions. J Nutr 125:1704S-1708S.
    • (1995) J Nutr , vol.125
    • Lemire, J.M.1    Archer, D.C.2    Beck, L.3    Spiegelberg, H.L.4
  • 25
    • 0036220629 scopus 로고    scopus 로고
    • The coming of age of 1,25-dihydroxyvitamin D(3) analogs as immunomodulatory agents
    • Mathieu C, Adorini L. 2002. The coming of age of 1,25-dihydroxyvitamin D(3) analogs as immunomodulatory agents. Trends Mol Med 8:174-179.
    • (2002) Trends Mol Med , vol.8 , pp. 174-179
    • Mathieu, C.1    Adorini, L.2
  • 26
    • 0002451327 scopus 로고    scopus 로고
    • Vitamin D and diabetes
    • Feldman D, Glorieux FH, Pike JW, editors. San Diego: Academic Press
    • Mathieu C, Casteels K, Boullion R. 1997. Vitamin D and diabetes. In: Feldman D, Glorieux FH, Pike JW, editors. Vitamin D. San Diego: Academic Press.
    • (1997) Vitamin D
    • Mathieu, C.1    Casteels, K.2    Boullion, R.3
  • 28
    • 0028357305 scopus 로고
    • Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3
    • Mathieu C, Waer M, Laureys J, Rutgeerts O, Bouillon R. 1994. Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3. Diabetologia 37:552-558.
    • (1994) Diabetologia , vol.37 , pp. 552-558
    • Mathieu, C.1    Waer, M.2    Laureys, J.3    Rutgeerts, O.4    Bouillon, R.5
  • 29
    • 0033975024 scopus 로고    scopus 로고
    • Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D3
    • Mattner F, Smiroldo S, Galbiati F, Muller M, Di Lucia P, Poliani PL, Martino G, Panina-Bordignon P, Adorini L. 2000. Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D3. Eur J Immunol 30:498-508.
    • (2000) Eur J Immunol , vol.30 , pp. 498-508
    • Mattner, F.1    Smiroldo, S.2    Galbiati, F.3    Muller, M.4    Di Lucia, P.5    Poliani, P.L.6    Martino, G.7    Panina-Bordignon, P.8    Adorini, L.9
  • 30
    • 0034283931 scopus 로고    scopus 로고
    • Mycophenolate mofetil impairs the maturation and function of murine dendritic cells
    • Mehling A, Grabbe S, Voskort M, Schwarz T, Luger TA, Beissert S. 2000. Mycophenolate mofetil impairs the maturation and function of murine dendritic cells. J Immunol 165:2374-2381.
    • (2000) J Immunol , vol.165 , pp. 2374-2381
    • Mehling, A.1    Grabbe, S.2    Voskort, M.3    Schwarz, T.4    Luger, T.A.5    Beissert, S.6
  • 31
    • 0034987088 scopus 로고    scopus 로고
    • Ligands for the vitamin D endocrine system: Different shapes function as agonists and antagonists for genomic and rapid response receptors or as a ligand for the plasma vitamin D binding protein
    • Norman AW, Ishizuka S, Okamura WH. 2001. Ligands for the vitamin D endocrine system: Different shapes function as agonists and antagonists for genomic and rapid response receptors or as a ligand for the plasma vitamin D binding protein. J Steroid Biochem Mol Biol 76:49-59.
    • (2001) J Steroid Biochem Mol Biol , vol.76 , pp. 49-59
    • Norman, A.W.1    Ishizuka, S.2    Okamura, W.H.3
  • 32
    • 0034101764 scopus 로고    scopus 로고
    • Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans
    • Pani MA, Knapp M, Donner H, Braun J, Baur MP, Usadel KH, Badenhoop K. 2000. Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans. Diabetes 49:504-507.
    • (2000) Diabetes , vol.49 , pp. 504-507
    • Pani, M.A.1    Knapp, M.2    Donner, H.3    Braun, J.4    Baur, M.P.5    Usadel, K.H.6    Badenhoop, K.7
  • 33
    • 0034161714 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 inhibits differentiation, maturation, activation and survival of dendritic cells leading to impaired alloreactive T cell activation
    • Penna G, Adorini L. 2000. 1,25-Dihydroxyvitamin D3 inhibits differentiation, maturation, activation and survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol 164:2405-2411.
    • (2000) J Immunol , vol.164 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 37
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
    • Salomon B, Lenschow DJ, Rhee L, Ashourian N, Singh B, Sharpe A, Bluestone JA. 2000. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12:431-440.
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1    Lenschow, D.J.2    Rhee, L.3    Ashourian, N.4    Singh, B.5    Sharpe, A.6    Bluestone, J.A.7
  • 38
    • 0031883711 scopus 로고    scopus 로고
    • Nuclear factor of activated T cells (NFAT) as a molecular target for 1α,25-dihydroxyvitamin D3-mediated effects
    • Takeuchi A, Reddy G, Kobayashi T, Okano T, Park J, Sharma S. 1998: Nuclear factor of activated T cells (NFAT) as a molecular target for 1α,25-dihydroxyvitamin D3-mediated effects. J Immunol 160:209-218.
    • (1998) J Immunol , vol.160 , pp. 209-218
    • Takeuchi, A.1    Reddy, G.2    Kobayashi, T.3    Okano, T.4    Park, J.5    Sharma, S.6
  • 39
    • 0032939358 scopus 로고    scopus 로고
    • Vitamin D supplement in early childhood and risk for type I (insulin-dependent) diabetes mellitus
    • The EURODIAB Substudy 2 Study Group. 1999. Vitamin D supplement in early childhood and risk for type I (insulin-dependent) diabetes mellitus. Diabetologia 42: 51-54.
    • (1999) Diabetologia , vol.42 , pp. 51-54
  • 40
    • 0028926524 scopus 로고
    • IL-12 administration induces Th1 cells and accelerates autoimmune diabetes in NOD mice
    • Trembleau S, Penna G, Bosi E, Mortara A, Gately MK, Adorini L. 1995. IL-12 administration induces Th1 cells and accelerates autoimmune diabetes in NOD mice. J Exp Med 181:817-821.
    • (1995) J Exp Med , vol.181 , pp. 817-821
    • Trembleau, S.1    Penna, G.2    Bosi, E.3    Mortara, A.4    Gately, M.K.5    Adorini, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.