-
1
-
-
0030846307
-
Creating isoprenoid diversity
-
Sacchettini, J.C., and Poulter, C.D. (1997) Creating Isoprenoid Diversity, Science 277, 1788-1789.
-
(1997)
Science
, vol.277
, pp. 1788-1789
-
-
Sacchettini, J.C.1
Poulter, C.D.2
-
2
-
-
0033527055
-
2-Methylhopanoids as biomarkers for cyanobacterial oxygenic photosynthesis
-
Summons, R.E., Jahnke, L.L., Hope, J.M., and Logan, G.A. (1999) 2-Methylhopanoids as Biomarkers for Cyanobacterial Oxygenic Photosynthesis, Nature 400, 554-557.
-
(1999)
Nature
, vol.400
, pp. 554-557
-
-
Summons, R.E.1
Jahnke, L.L.2
Hope, J.M.3
Logan, G.A.4
-
3
-
-
3242815993
-
The biosynthesis of mevalonic acid
-
Ferguson, J.J., Durr, I.F., and Rudney, H. (1959) The Biosynthesis of Mevalonic Acid, Proc. Nat. Acad. Sci. USA 45, 499-504.
-
(1959)
Proc. Nat. Acad. Sci. USA
, vol.45
, pp. 499-504
-
-
Ferguson, J.J.1
Durr, I.F.2
Rudney, H.3
-
4
-
-
0000007179
-
Mevalonic kinase: Purification and properties
-
Tchen, T.T. (1958) Mevalonic Kinase: Purification and Properties, J. Biol. Chem. 233, 1100-1103.
-
(1958)
J. Biol. Chem.
, vol.233
, pp. 1100-1103
-
-
Tchen, T.T.1
-
5
-
-
3242766709
-
On the biosynthesis of terpenes. XIV. On the determination of phosphomevalonic acid kinase and pyrophosphomevalonic acid decarboxylase in cell extracts
-
Tada, M., and Lynen, F. (1961) On the Biosynthesis of Terpenes. XIV. On the Determination of Phosphomevalonic Acid Kinase and Pyrophosphomevalonic Acid Decarboxylase in Cell Extracts, J. Biochem. 49, 758-764.
-
(1961)
J. Biochem.
, vol.49
, pp. 758-764
-
-
Tada, M.1
Lynen, F.2
-
6
-
-
0005226507
-
Biosynthesis of terpenes. VII. Isopentenyl pyrophosphate isomerase
-
Agranoff, B.W., Eggerer, H., Henning, U., and Lynen, F. (1960) Biosynthesis of Terpenes. VII. Isopentenyl Pyrophosphate Isomerase, J. Biol. Chem. 235, 326-332.
-
(1960)
J. Biol. Chem.
, vol.235
, pp. 326-332
-
-
Agranoff, B.W.1
Eggerer, H.2
Henning, U.3
Lynen, F.4
-
7
-
-
0018199226
-
2-isopentenyl) adenosine and its nucleotide: Interaction with purified tRNAs and with bases, nucleosides and nucleotides of the isopentenyladenosine family
-
2-isopentenyl) Adenosine and Its Nucleotide: Interaction with Purified tRNAs and with Bases, Nucleosides and Nucleotides of the Isopentenyladenosine Family, Nucleic Acids Res. 5, 3439-3455.
-
(1978)
Nucleic Acids Res.
, vol.5
, pp. 3439-3455
-
-
Milstone, D.S.1
Vold, B.S.2
Glitz, D.G.3
Shutt, N.4
-
8
-
-
0017837485
-
5′-AMP is a direct precursor of cytokinin in Dictyostelium discoideum
-
Taya, Y., Tanaka, Y., and Nishimura, S. (1978) 5′-AMP Is a Direct Precursor of Cytokinin in Dictyostelium discoideum, Nature 271, 545-547.
-
(1978)
Nature
, vol.271
, pp. 545-547
-
-
Taya, Y.1
Tanaka, Y.2
Nishimura, S.3
-
9
-
-
0000676652
-
The prenyl transfer reaction: Enzymic and mechanistic studies on the 1′-4 coupling reaction in the terpene biosynthetic pathway
-
Poulter, C.D., and Rilling, H.C. (1978) The Prenyl Transfer Reaction: Enzymic and Mechanistic Studies on the 1′-4 Coupling Reaction in the Terpene Biosynthetic Pathway, Acc. Chem. Res. 11, 307-313.
-
(1978)
Acc. Chem. Res.
, vol.11
, pp. 307-313
-
-
Poulter, C.D.1
Rilling, H.C.2
-
10
-
-
0024686637
-
Geranyl pyrophosphate synthase: Characterization of the enzyme and evidence that this chain-length-specific prenyltransferase is associated with monoterpene biosynthesis in sage (Salvia officinalis)
-
Croteau, R., and Purkett, P.T. (1989) Geranyl Pyrophosphate Synthase: Characterization of the Enzyme and Evidence That This Chain-Length-Specific Prenyltransferase Is Associated with Monoterpene Biosynthesis in Sage (Salvia officinalis), Arch. Biochem. Biophys. 271, 524-535.
-
(1989)
Arch. Biochem. Biophys.
, vol.271
, pp. 524-535
-
-
Croteau, R.1
Purkett, P.T.2
-
11
-
-
0015919475
-
Squalene synthetase. 3. Mechanism of the reaction
-
Beytia, E., Qureshi, A.A., and Porter, J.W. (1973) Squalene Synthetase. 3. Mechanism of the Reaction, J. Biol. Chem. 248, 1856-1867.
-
(1973)
J. Biol. Chem.
, vol.248
, pp. 1856-1867
-
-
Beytia, E.1
Qureshi, A.A.2
Porter, J.W.3
-
12
-
-
0022109072
-
Isoprenoid enzyme systems of silkworm. II. Formation of the juvenile hormone skeletons by farnesyl pyrophosphate synthetase II
-
Tokyo
-
Koyama, T., Matsubara, M., and Ogura, K. (1985) Isoprenoid Enzyme Systems of Silkworm. II. Formation of the Juvenile Hormone Skeletons by Farnesyl Pyrophosphate Synthetase II, J. Biochem. 98 (Tokyo), 457-463.
-
(1985)
J. Biochem.
, vol.98
, pp. 457-463
-
-
Koyama, T.1
Matsubara, M.2
Ogura, K.3
-
13
-
-
0000099415
-
Purification of geranylgeranyl pyrophosphate synthetase from Micrococcus lysodeikticus
-
Kandutsch, A.A., Paulus, H., Levin, E., and Bloch, K. (1964) Purification of Geranylgeranyl Pyrophosphate Synthetase from Micrococcus lysodeikticus, J. Biol. Chem. 239, 2507-2515.
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2507-2515
-
-
Kandutsch, A.A.1
Paulus, H.2
Levin, E.3
Bloch, K.4
-
14
-
-
0025194466
-
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides
-
Reiss, Y., Goldstein, J.L., Seabra, M.C., Casey, P.J., and Brown, M.S. (1990) Inhibition of Purified p21ras Farnesyl:Protein Transferase by Cys-AAX Tetrapeptides, Cell 62, 81-88.
-
(1990)
Cell
, vol.62
, pp. 81-88
-
-
Reiss, Y.1
Goldstein, J.L.2
Seabra, M.C.3
Casey, P.J.4
Brown, M.S.5
-
15
-
-
0026806554
-
Mammalian protein geranylgeranyltransferase. Subunit composition and metal requirements
-
Moomaw, J.F., and Casey, P.J. (1992) Mammalian Protein Geranylgeranyltransferase. Subunit Composition and Metal Requirements, J. Biol. Chem. 267, 17438-17443.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17438-17443
-
-
Moomaw, J.F.1
Casey, P.J.2
-
16
-
-
0027416643
-
Purification of a mammalian protein geranylgeranyltransferase. Formation and catalytic properties of an enzyme-geranylgeranyl pyrophosphate complex
-
Yokoyama, K., and Gelb, M.H. (1993) Purification of a Mammalian Protein Geranylgeranyltransferase. Formation and Catalytic Properties of an Enzyme-Geranylgeranyl Pyrophosphate Complex, J. Biol. Chem. 268, 4055-4060.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 4055-4060
-
-
Yokoyama, K.1
Gelb, M.H.2
-
17
-
-
0027298707
-
cDNA cloning and expression of the alpha and beta subunits of rat rab geranylgeranyl transferase
-
Armstrong, S.A., Seabra, M.C., Sudhof, T.C., Goldstein, J.L., and Brown, M.S. (1993) cDNA Cloning and Expression of the Alpha and Beta Subunits of Rat Rab Geranylgeranyl Transferase, J. Biol. Chem. 268, 12221-12229.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12221-12229
-
-
Armstrong, S.A.1
Seabra, M.C.2
Sudhof, T.C.3
Goldstein, J.L.4
Brown, M.S.5
-
18
-
-
0034672694
-
Isoprenyl diphosphate synthases
-
Wang, K.C., and Ohnuma, S. (2000) Isoprenyl Diphosphate Synthases, Biochim. Biophys. Acta 1529, 33-48.
-
(2000)
Biochim. Biophys. Acta
, vol.1529
, pp. 33-48
-
-
Wang, K.C.1
Ohnuma, S.2
-
19
-
-
0027433040
-
Biosynthesis of the side chain of ubiquinone:trans-prenyltransferase in rat liver microsomes
-
Teclebrhan, H., Olsson, J., Swiezewska, E., and Dallner, G. (1993) Biosynthesis of the Side Chain of Ubiquinone: trans-Prenyltransferase in Rat Liver Microsomes, J. Biol. Chem. 268, 23081-23086.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 23081-23086
-
-
Teclebrhan, H.1
Olsson, J.2
Swiezewska, E.3
Dallner, G.4
-
20
-
-
0025793572
-
Variable product specificity of microsomal dehydrodolichyl diphosphate synthase from rat liver
-
Matsuoka, S., Sagami, H., Kurisaki, A., and Ogura, K. (1991) Variable Product Specificity of Microsomal Dehydrodolichyl Diphosphate Synthase from Rat Liver, J. Biol. Chem. 266, 3464-3468.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 3464-3468
-
-
Matsuoka, S.1
Sagami, H.2
Kurisaki, A.3
Ogura, K.4
-
21
-
-
0020807234
-
Long-chain betulaprenol-type polyprenols from the leaves of Ginkgo biloba
-
Ibata, K., Mizuno, M., Takigawa, T., and Tanaka, Y. (1983) Long-Chain Betulaprenol-Type Polyprenols from the Leaves of Ginkgo biloba, Biochem. J. 213, 305-311.
-
(1983)
Biochem. J.
, vol.213
, pp. 305-311
-
-
Ibata, K.1
Mizuno, M.2
Takigawa, T.3
Tanaka, Y.4
-
22
-
-
0025696050
-
Cloning and nucleotide sequence of the ispA gene responsible for farnesyl diphosphate synthase activity in Escherichia coli
-
Fujisaki, S., Hara, H., Nishimura, Y., Horiuchi, K., and Nishino, T. (1990) Cloning and Nucleotide Sequence of the ispA Gene Responsible for Farnesyl Diphosphate Synthase Activity in Escherichia coli, J. Biochem. (Tokyo) 108, 995-1000.
-
(1990)
J. Biochem. (Tokyo)
, vol.108
, pp. 995-1000
-
-
Fujisaki, S.1
Hara, H.2
Nishimura, Y.3
Horiuchi, K.4
Nishino, T.5
-
23
-
-
0345313624
-
Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: Cloning, expression, and characterization of the essential uppS gene
-
Apfel, C.M., Takacs, B., Fountoulakis, M., Stieger, M., and Keck, W. (1999) Use of Genomics to Identify Bacterial Undecaprenyl Pyrophosphate Synthetase: Cloning, Expression, and Characterization of the Essential uppS Gene, J. Bacteriol. 181, 483-492.
-
(1999)
J. Bacteriol.
, vol.181
, pp. 483-492
-
-
Apfel, C.M.1
Takacs, B.2
Fountoulakis, M.3
Stieger, M.4
Keck, W.5
-
24
-
-
0030628018
-
Polyprenyl diphosphate synthases
-
Ogura, K., Koyama, T., and Sagami, H. (1997) Polyprenyl Diphosphate Synthases, Subcell. Biochem. 28, 57-87.
-
(1997)
Subcell. Biochem.
, vol.28
, pp. 57-87
-
-
Ogura, K.1
Koyama, T.2
Sagami, H.3
-
25
-
-
0026618026
-
Identification of a cDNA for the plastid-located geranylgeranyl pyrophosphate synthase from Capsicum annuum: Correlative increase in enzyme activity and transcript level during fruit ripening
-
Kuntz, M., Romer, S., Suire, C., Hugueney, P., Weil, J.H., Schantz, R., and Camara, B. (1992) Identification of a cDNA for the Plastid-Located Geranylgeranyl Pyrophosphate Synthase from Capsicum annuum: Correlative Increase in Enzyme Activity and Transcript Level During Fruit Ripening, Plant J. 2, 25-34.
-
(1992)
Plant J.
, vol.2
, pp. 25-34
-
-
Kuntz, M.1
Romer, S.2
Suire, C.3
Hugueney, P.4
Weil, J.H.5
Schantz, R.6
Camara, B.7
-
26
-
-
0030696041
-
Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol
-
Sprenger, G.A., Schorken, U., Wiegert, T., Grolle, S., de Graaf, A.A., Taylor, S.V., Begley, T.P., Bringer-Meyer, S., and Sahm, H. (1997) Identification of a Thiamin-Dependent Synthase in Escherichia coli Required for the Formation of the 1-Deoxy-D-xylulose 5-phosphate Precursor to Isoprenoids, Thiamin, and Pyridoxol, Proc. Nat. Acad. Sci. USA 94, 12857-12862.
-
(1997)
Proc. Nat. Acad. Sci. USA
, vol.94
, pp. 12857-12862
-
-
Sprenger, G.A.1
Schorken, U.2
Wiegert, T.3
Grolle, S.4
De Graaf, A.A.5
Taylor, S.V.6
Begley, T.P.7
Bringer-Meyer, S.8
Sahm, H.9
-
27
-
-
0343614184
-
A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway
-
Lange, B.M., Wildung, M.R., McCaskill, D., and Croteau, R. (1998) A Family of Transketolases That Directs Isoprenoid Biosynthesis via a Mevalonate-Independent Pathway, Proc. Nat. Acad. Sci. USA 95, 2100-2104.
-
(1998)
Proc. Nat. Acad. Sci. USA
, vol.95
, pp. 2100-2104
-
-
Lange, B.M.1
Wildung, M.R.2
McCaskill, D.3
Croteau, R.4
-
28
-
-
0032170425
-
The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms
-
Eisenreich, W., Schwarz, M., Cartayrade, A., Arigoni, D., Zenk, M.H., and Bacher, A. (1998) The Deoxyxylulose Phosphate Pathway of Terpenoid Biosynthesis in Plants and Microorganisms, Chem. Biol. 5, R221-R233.
-
(1998)
Chem. Biol.
, vol.5
-
-
Eisenreich, W.1
Schwarz, M.2
Cartayrade, A.3
Arigoni, D.4
Zenk, M.H.5
Bacher, A.6
-
29
-
-
0024061058
-
Prokaryotic hopanoids: The biosynthesis of the bacteriohopane skeleton. Formation of isoprenic units from two distinct acetate pools and a novel type of carbon/carbon linkage between a triterpene and D-ribose
-
Flesch, G., and Rohmer, M. (1988) Prokaryotic Hopanoids: The Biosynthesis of the Bacteriohopane Skeleton. Formation of Isoprenic Units from Two Distinct Acetate Pools and a Novel Type of Carbon/Carbon Linkage Between a Triterpene and D-Ribose, Eur. J. Biochem. 175, 405-411.
-
(1988)
Eur. J. Biochem.
, vol.175
, pp. 405-411
-
-
Flesch, G.1
Rohmer, M.2
-
30
-
-
0033598845
-
Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: Isopentenyl monophosphate kinase catalyzes the terminal enzymatic step
-
Lange, B.M., and Croteau, R. (1999) Isopentenyl Diphosphate Biosynthesis via a Mevalonate-Independent Pathway: Isopentenyl Monophosphate Kinase Catalyzes the Terminal Enzymatic Step, Proc. Nat. Acad. Sci. USA 96, 13714-13719.
-
(1999)
Proc. Nat. Acad. Sci. USA
, vol.96
, pp. 13714-13719
-
-
Lange, B.M.1
Croteau, R.2
-
31
-
-
0031474261
-
Two independent biochemical pathways for isopentenyl diphosphate and isoprenoid biosynthesis in higher plants
-
Lichtenthaler, H.K., Rohmer, M., and Schwender, J. (1997) Two Independent Biochemical Pathways for Isopentenyl Diphosphate and Isoprenoid Biosynthesis in Higher Plants, Physiol. Plant. 101, 643-652.
-
(1997)
Physiol. Plant.
, vol.101
, pp. 643-652
-
-
Lichtenthaler, H.K.1
Rohmer, M.2
Schwender, J.3
-
32
-
-
0034700150
-
Isoprenoid biosynthesis: The evolution of two ancient and distinct pathways across genomes
-
Lange, B.M., Rujan, T., Martin, W., and Croteau, R. (2000) Isoprenoid Biosynthesis: The Evolution of Two Ancient and Distinct Pathways Across Genomes, Proc. Nat. Acad. Sci. USA 97, 13172-13177.
-
(2000)
Proc. Nat. Acad. Sci. USA
, vol.97
, pp. 13172-13177
-
-
Lange, B.M.1
Rujan, T.2
Martin, W.3
Croteau, R.4
-
33
-
-
0033859551
-
The role of lateral gene transfer in the evolution of isoprenoid biosynthesis pathways
-
Boucher, Y., and Doolittle, W.F. (2000) The Role of Lateral Gene Transfer in the Evolution of Isoprenoid Biosynthesis Pathways, Mol. Microbiol. 37, 703-716.
-
(2000)
Mol. Microbiol.
, vol.37
, pp. 703-716
-
-
Boucher, Y.1
Doolittle, W.F.2
-
34
-
-
0024730975
-
Prokaryotic triterpenoids. A novel hopanoid from the ethanol-producing bacterium zymomonas mobilis
-
Flesch, G., and Rohmer, M. (1989) Prokaryotic Triterpenoids. A Novel Hopanoid from the Ethanol-Producing Bacterium Zymomonas mobilis, Biochem. J. 262, 673-675.
-
(1989)
Biochem. J.
, vol.262
, pp. 673-675
-
-
Flesch, G.1
Rohmer, M.2
-
35
-
-
0027368126
-
Isoprenoid biosynthesis in bacteria: A novel pathway for the early steps leading to isopentenyl diphosphate
-
Rohmer, M., Knani, M., Simonin, P., Sutter, B., and Sahm, H. (1993) Isoprenoid Biosynthesis in Bacteria: A Novel Pathway for the Early Steps Leading to Isopentenyl Diphosphate, Biochem. J. 295, 517-524.
-
(1993)
Biochem. J.
, vol.295
, pp. 517-524
-
-
Rohmer, M.1
Knani, M.2
Simonin, P.3
Sutter, B.4
Sahm, H.5
-
36
-
-
0000725115
-
Distribution of mevalonate and glyceraldehyde 3-phosphate/pyruvate routes for isoprenoid biosynthesis in some gram-negative bacteria and mycobacteria
-
Putra, S.R., Disch, A., Bravo, J.M., and Rohmer, M. (1998) Distribution of Mevalonate and Glyceraldehyde 3-Phosphate/Pyruvate Routes for Isoprenoid Biosynthesis in Some Gram-Negative Bacteria and Mycobacteria, FEMS Microbiol. Lett. 164, 169-175.
-
(1998)
FEMS Microbiol. Lett.
, vol.164
, pp. 169-175
-
-
Putra, S.R.1
Disch, A.2
Bravo, J.M.3
Rohmer, M.4
-
37
-
-
0030850424
-
Biosynthesis of the labdane diterpene marrubiin in Marrubium vulgare via a non-mevalonate pathway
-
Knöss, W., Reuter, B., and Zapp, J. (1997) Biosynthesis of the Labdane Diterpene Marrubiin in Marrubium vulgare via a Non-mevalonate Pathway, Biochem. J. 326, 449-454.
-
(1997)
Biochem. J.
, vol.326
, pp. 449-454
-
-
Knöss, W.1
Reuter, B.2
Zapp, J.3
-
38
-
-
0029938615
-
Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus
-
Schwender, J., Seemann, M., Lichtenthaler, H.K., and Rohmer, M. (1996) Biosynthesis of Isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a Novel Pyruvate/Glyceraldehyde 3-Phosphate Non-mevalonate Pathway in the Green Alga Scenedesmus obliquus, Biochem. J. 316, 73-80.
-
(1996)
Biochem. J.
, vol.316
, pp. 73-80
-
-
Schwender, J.1
Seemann, M.2
Lichtenthaler, H.K.3
Rohmer, M.4
-
39
-
-
0031731697
-
On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts
-
Disch, A., and Rohmer, M. (1998) On the Absence of the Glyceraldehyde 3-Phosphate/Pyruvate Pathway for Isoprenoid Biosynthesis in Fungi and Yeasts, FEMS Microbiol. Lett. 168, 201-208.
-
(1998)
FEMS Microbiol. Lett.
, vol.168
, pp. 201-208
-
-
Disch, A.1
Rohmer, M.2
-
40
-
-
0036676584
-
Strategies for transgenic manipulation of monoterpene biosynthesis in plants
-
Mahmoud, S.S., and Croteau, R.B. (2002) Strategies for Transgenic Manipulation of Monoterpene Biosynthesis in Plants, Trends Plant Sci. 7, 366-373.
-
(2002)
Trends Plant Sci.
, vol.7
, pp. 366-373
-
-
Mahmoud, S.S.1
Croteau, R.B.2
-
41
-
-
0004199544
-
-
John Wiley & Sons, New York
-
Porter, J.W., and Spurgeon, S.L. (1981) Biosynthesis of Isoprenoid Compounds, Vol. 1, John Wiley & Sons, New York.
-
(1981)
Biosynthesis of Isoprenoid Compounds
, vol.1
-
-
Porter, J.W.1
Spurgeon, S.L.2
-
42
-
-
0003724933
-
-
Kluwer Academic, Dordrecht
-
Harrewijn, P., van Oosten, A.M., and Piron, P.G.M. (2001) Natural Terpenoids as Messengers: A Multidisciplinary Study of Their Production, Biological Functions and Practical Applications, pp. 1-9, Kluwer Academic, Dordrecht.
-
(2001)
Natural Terpenoids as Messengers: A Multidisciplinary Study of Their Production, Biological Functions and Practical Applications
, pp. 1-9
-
-
Harrewijn, P.1
Van Oosten, A.M.2
Piron, P.G.M.3
-
43
-
-
0032980875
-
Prevention and therapy of cancer by dietary monoterpenes
-
Crowell, P.L. (1999) Prevention and Therapy of Cancer by Dietary Monoterpenes, J. Nutr. 129, 775S-778S.
-
(1999)
J. Nutr.
, vol.129
-
-
Crowell, P.L.1
-
44
-
-
0028229474
-
Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras
-
Gould, M.N., Moore, C.J., Zhang, R., Wang, B., Kennan, W.S., and Haag, J.D. (1994) Limonene Chemoprevention of Mammary Carcinoma Induction Following Direct in situ Transfer of v-Ha-ras, Cancer Res. 54, 3540-3543.
-
(1994)
Cancer Res.
, vol.54
, pp. 3540-3543
-
-
Gould, M.N.1
Moore, C.J.2
Zhang, R.3
Wang, B.4
Kennan, W.S.5
Haag, J.D.6
-
45
-
-
0022574881
-
Regression of rat primary mammary tumors following dietary D-limonene
-
Elegbede, J.A., Elson, C.E., Tanner, M.A., Qureshi, A., and Gould, M.N. (1986) Regression of Rat Primary Mammary Tumors Following Dietary D-Limonene, J. Natl. Cancer Inst. 76, 323-325.
-
(1986)
J. Natl. Cancer Inst.
, vol.76
, pp. 323-325
-
-
Elegbede, J.A.1
Elson, C.E.2
Tanner, M.A.3
Qureshi, A.4
Gould, M.N.5
-
46
-
-
0027965512
-
Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene
-
Haag, J.D., and Gould, M.N. (1994) Mammary Carcinoma Regression Induced by Perillyl Alcohol, a Hydroxylated Analog of Limonene, Cancer Chemother. Pharmacol. 34, 477-483.
-
(1994)
Cancer Chemother. Pharmacol.
, vol.34
, pp. 477-483
-
-
Haag, J.D.1
Gould, M.N.2
-
47
-
-
0029132661
-
Chemotherapy of pancreatic cancer with the monoterpene perillyl alcohol
-
Stark, M.J., Burke, Y.D., McKinzie, J.H., Ayoubi, A.S., and Crowell, P.L. (1995) Chemotherapy of Pancreatic Cancer with the Monoterpene Perillyl Alcohol, Cancer Lett. 96, 15-21.
-
(1995)
Cancer Lett.
, vol.96
, pp. 15-21
-
-
Stark, M.J.1
Burke, Y.D.2
McKinzie, J.H.3
Ayoubi, A.S.4
Crowell, P.L.5
-
48
-
-
0141791063
-
Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro
-
Elegbede, J.A., Flores, R., and Wang, R.C. (2003) Perillyl Alcohol and Perillaldehyde Induced Cell Cycle Arrest and Cell Death in BroTo and A549 Cells Cultured in vitro, Life Sci. 73, 2831-2840.
-
(2003)
Life Sci.
, vol.73
, pp. 2831-2840
-
-
Elegbede, J.A.1
Flores, R.2
Wang, R.C.3
-
49
-
-
0141727521
-
Cytotoxicity of perillyl alcohol against cancer cells is potentiated by hyperthermia
-
Ahn, K.J., Lee, C.K., Choi, E.K., Griffin, R., Song, C.W., and Park, H.J. (2003) Cytotoxicity of Perillyl Alcohol Against Cancer Cells Is Potentiated by Hyperthermia, Int. J. Radiat. Oncol. Biol. Phys. 57, 813-819.
-
(2003)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.57
, pp. 813-819
-
-
Ahn, K.J.1
Lee, C.K.2
Choi, E.K.3
Griffin, R.4
Song, C.W.5
Park, H.J.6
-
50
-
-
0033984370
-
Perillyl alcohol, an inhibitor of geranylgeranyl transferase, induces apoptosis of immortalized human vascular smooth muscle cells in vitro
-
Unlu, S., Mason, C.D., Schachter, M., and Hughes, A.D. (2000) Perillyl Alcohol, an Inhibitor of Geranylgeranyl Transferase, Induces Apoptosis of Immortalized Human Vascular Smooth Muscle Cells in vitro, J. Cardiovasc. Pharmacol. 35, 341-344.
-
(2000)
J. Cardiovasc. Pharmacol.
, vol.35
, pp. 341-344
-
-
Unlu, S.1
Mason, C.D.2
Schachter, M.3
Hughes, A.D.4
-
51
-
-
0032827382
-
Perillyl alcohol selectively induces G0/G1 arrest and apoptosis in Bcr/Abl-transformed myeloid cell lines
-
Sahin, M.B., Perman, S.M., Jenkins, G., and Clark, S.S. (1999) Perillyl Alcohol Selectively Induces G0/G1 Arrest and Apoptosis in Bcr/Abl-Transformed Myeloid Cell Lines, Leukemia. 13, 1581-1591.
-
(1999)
Leukemia
, vol.13
, pp. 1581-1591
-
-
Sahin, M.B.1
Perman, S.M.2
Jenkins, G.3
Clark, S.S.4
-
52
-
-
15644376846
-
Phase I clinical trial of perillyl alcohol administered daily
-
Ripple, G.H., Gould, M.N., Stewart, J.A., Tutsch, K.D., Arzoomanian, R.Z., Alberti, D., Feierabend, C., Pomplun, M., Wilding, G., and Bailey, H.H. (1998) Phase I Clinical Trial of Perillyl Alcohol Administered Daily, Clin. Cancer Res. 4, 1159-1164.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 1159-1164
-
-
Ripple, G.H.1
Gould, M.N.2
Stewart, J.A.3
Tutsch, K.D.4
Arzoomanian, R.Z.5
Alberti, D.6
Feierabend, C.7
Pomplun, M.8
Wilding, G.9
Bailey, H.H.10
-
53
-
-
0031834303
-
Phase I and pharmacokinetic study of D-limonene in patients with advanced cancer
-
Cancer Research Campaign Phase I/II Clinical Trials Committee
-
Vigushin, D.M., Poon, G.K., Boddy, A., English, J., Halbert, G.W., Pagonis, C., Jarman, M., and Coombes, R.C. (1998) Phase I and Pharmacokinetic Study of D-Limonene in Patients with Advanced Cancer. Cancer Research Campaign Phase I/II Clinical Trials Committee, Cancer Chemother. Pharmacol. 42, 111-117.
-
(1998)
Cancer Chemother. Pharmacol.
, vol.42
, pp. 111-117
-
-
Vigushin, D.M.1
Poon, G.K.2
Boddy, A.3
English, J.4
Halbert, G.W.5
Pagonis, C.6
Jarman, M.7
Coombes, R.C.8
-
54
-
-
0033875499
-
Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies
-
Hudes, G.R., Szarka, C.E., Adams, A., Ranganathan, S., McCauley, R.A., Weiner, L.M., Langer, C.J., Litwin, S., Yeslow, G., Halberr, T., et al. (2000) Phase I Pharmacokinetic Trial of Perillyl Alcohol (NSC 641066) in Patients with Refractory Solid Malignancies, Clin. Cancer Res. 6, 3071-3080.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3071-3080
-
-
Hudes, G.R.1
Szarka, C.E.2
Adams, A.3
Ranganathan, S.4
McCauley, R.A.5
Weiner, L.M.6
Langer, C.J.7
Litwin, S.8
Yeslow, G.9
Halberr, T.10
-
55
-
-
0033976684
-
Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day
-
Ripple, G.H., Gould, M.N., Arzoomanian, R.Z., Alberti, D., Feierabend, C., Simon, K., Binger, K., Tutsch, K.D., Pomplun, M., Wahamaki, A., et al. (2000) Phase I Clinical and Pharmacokinetic Study of Perillyl Alcohol Administered Four Times a Day, Clin. Cancer Res. 6, 390-396.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 390-396
-
-
Ripple, G.H.1
Gould, M.N.2
Arzoomanian, R.Z.3
Alberti, D.4
Feierabend, C.5
Simon, K.6
Binger, K.7
Tutsch, K.D.8
Pomplun, M.9
Wahamaki, A.10
-
56
-
-
0036491156
-
Phase I study of perillyl alcohol in patients with refractory malignancies
-
Murren, J.R., Pizzorno, G., DiStasio, S.A., McKeon, A., Peccerillo, K., Gollerkari, A., McMurray, W., Burtness, B.A., Rutherford, T., Li, X., et al. (2002) Phase I Study of Perillyl Alcohol in Patients with Refractory Malignancies, Cancer Biol. Ther. 1, 130-135.
-
(2002)
Cancer Biol. Ther.
, vol.1
, pp. 130-135
-
-
Murren, J.R.1
Pizzorno, G.2
DiStasio, S.A.3
McKeon, A.4
Peccerillo, K.5
Gollerkari, A.6
McMurray, W.7
Burtness, B.A.8
Rutherford, T.9
Li, X.10
-
57
-
-
3242742790
-
A phase I trial of perillyl alcohol administered 4 times daily for 14 days out of 28 days
-
in press
-
Bailey, H.H., Wilding, G., Tutsch, K.D., Arzoomanian, R.Z., Alberti, D., Feierabend, K.S., Marnocha, R., Holstein, S.A., Stewart, J., Lewis, K.A., and Hohl, R.J. (2004) A Phase I Trial of Perillyl Alcohol Administered 4 Times Daily for 14 Days out of 28 Days, Cancer Chemother. Pharmacol., in press.
-
(2004)
Cancer Chemother. Pharmacol.
-
-
Bailey, H.H.1
Wilding, G.2
Tutsch, K.D.3
Arzoomanian, R.Z.4
Alberti, D.5
Feierabend, K.S.6
Marnocha, R.7
Holstein, S.A.8
Stewart, J.9
Lewis, K.A.10
Hohl, R.J.11
-
58
-
-
0025952954
-
Selective inhibition of isoprenylation of 21-26 kDa proteins by the anticarcinogen D-limonene and its metabolites
-
Crowell, P.L., Chang, R.R., Ren, Z.B., Elson, C.E., and Gould, M.N. (1991) Selective Inhibition of Isoprenylation of 21-26 kDa Proteins by the Anticarcinogen D-Limonene and Its Metabolites, J. Biol. Chem. 266, 17679-17685.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 17679-17685
-
-
Crowell, P.L.1
Chang, R.R.2
Ren, Z.B.3
Elson, C.E.4
Gould, M.N.5
-
59
-
-
0029125753
-
Differential effects of monoterpenes and lovastatin on RAS processing
-
Hohl, R.J., and Lewis, K. (1995) Differential Effects of Monoterpenes and Lovastatin on RAS Processing, J. Biol. Chem. 270, 17508-17512.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17508-17512
-
-
Hohl, R.J.1
Lewis, K.2
-
60
-
-
0142074249
-
Monoterpene regulation of Ras and Ras-related protein expression
-
Holstein, S.A., and Hohl, R.J. (2003) Monoterpene Regulation of Ras and Ras-Related Protein Expression, J. Lipid Res. 44, 1209-1215.
-
(2003)
J. Lipid Res.
, vol.44
, pp. 1209-1215
-
-
Holstein, S.A.1
Hohl, R.J.2
-
61
-
-
0032728951
-
African elephant sesquiterpenes
-
Goodwin, T.E., Rasmussen, E.L., Guinn, A.C., McKelvey, S.S., Gunawardena, R., Riddle, S.W., and Riddle, H.S. (1999) African Elephant Sesquiterpenes, J. Nat. Prod. 62, 1570-1572.
-
(1999)
J. Nat. Prod.
, vol.62
, pp. 1570-1572
-
-
Goodwin, T.E.1
Rasmussen, E.L.2
Guinn, A.C.3
McKelvey, S.S.4
Gunawardena, R.5
Riddle, S.W.6
Riddle, H.S.7
-
62
-
-
0037252940
-
New terpene hydrocarbons from the alligatoridae (Crocodylia, Reptilia)
-
Schulz, S., Kruckert, K., and Weldon, P.J. (2003) New Terpene Hydrocarbons from the Alligatoridae (Crocodylia, Reptilia), J. Nat. Prod. 66, 34-38.
-
(2003)
J. Nat. Prod.
, vol.66
, pp. 34-38
-
-
Schulz, S.1
Kruckert, K.2
Weldon, P.J.3
-
63
-
-
0025064030
-
Chemistry of male dominance in the house mouse, Mus domesticus
-
Novotny, M., Harvey, S., and Jemiolo, B. (1990) Chemistry of Male Dominance in the House Mouse, Mus domesticus, Experientia 46, 109-113.
-
(1990)
Experientia
, vol.46
, pp. 109-113
-
-
Novotny, M.1
Harvey, S.2
Jemiolo, B.3
-
64
-
-
0036756619
-
Sex attractant pheromone of the red-shouldered stink bug Thyanta pallidovirens: A pheromone blend with multiple redundant components
-
McBrien, H.L., Millar, J.G., Rice, R.E., McElfresh, J.S., Cullen, E., and Zalom, F.G. (2002) Sex Attractant Pheromone of the Red-Shouldered Stink Bug Thyanta pallidovirens: A Pheromone Blend with Multiple Redundant Components, J. Chem. Ecol. 28, 1797-1818.
-
(2002)
J. Chem. Ecol.
, vol.28
, pp. 1797-1818
-
-
McBrien, H.L.1
Millar, J.G.2
Rice, R.E.3
McElfresh, J.S.4
Cullen, E.5
Zalom, F.G.6
-
65
-
-
0026827425
-
Trans-beta-farnesene as a feeding stimulant for the sand fly Lutzomyia longipalpis (Diptera: Psychodidae)
-
Tesh, R.B., Guzman, H., and Wilson, M.L. (1992) Trans-Beta-Farnesene as a Feeding Stimulant for the Sand Fly Lutzomyia longipalpis (Diptera: Psychodidae), J. Med. Entomol. 29, 226-231.
-
(1992)
J. Med. Entomol.
, vol.29
, pp. 226-231
-
-
Tesh, R.B.1
Guzman, H.2
Wilson, M.L.3
-
66
-
-
0037357928
-
Interspecific variation in terpenoid composition of defensive secretions of European Reticulitermes termites
-
Quintana, A., Reinhard, J., Faure, R., Uva, P., Bagnères, A.G., Massiot, G., and Clément, J.L. (2003) Interspecific Variation in Terpenoid Composition of Defensive Secretions of European Reticulitermes Termites, J. Chem. Ecol. 29, 639-652.
-
(2003)
J. Chem. Ecol.
, vol.29
, pp. 639-652
-
-
Quintana, A.1
Reinhard, J.2
Faure, R.3
Uva, P.4
Bagnères, A.G.5
Massiot, G.6
Clément, J.L.7
-
67
-
-
0034840417
-
Conjugated triene oxidation products of α-farnesene induce symptoms of superficial scald on stored apples
-
Rowan, D.D., Hunt, M.B., Fielder, S., Norris, J., and Sherburn, M.S. (2001) Conjugated Triene Oxidation Products of α-Farnesene Induce Symptoms of Superficial Scald on Stored Apples, J. Agric. Food. Chem. 49, 2780-2787.
-
(2001)
J. Agric. Food. Chem.
, vol.49
, pp. 2780-2787
-
-
Rowan, D.D.1
Hunt, M.B.2
Fielder, S.3
Norris, J.4
Sherburn, M.S.5
-
68
-
-
0036009884
-
Structure-activity relationships of seco-Prezizaane terpenoids in γ-aminobutyric acid receptors of houseflies and rats
-
Kuriyama, T., Schmidt, T.J., Okuyama, E., and Ozoe, Y. (2002) Structure-Activity Relationships of seco-Prezizaane Terpenoids in γ-Aminobutyric Acid Receptors of Houseflies and Rats, Bioorg. Med. Chem. 10, 1873-1881.
-
(2002)
Bioorg. Med. Chem.
, vol.10
, pp. 1873-1881
-
-
Kuriyama, T.1
Schmidt, T.J.2
Okuyama, E.3
Ozoe, Y.4
-
69
-
-
0033760941
-
Inhibition of the transcription factor NF-κB by sesquiterpene lactones from Podachaenium eminens
-
Castro, V., Murillo, R., Klaas, C.A., Meunier, C., Mora, G., Pahl, H.L., and Merfort, I. (2000) Inhibition of the Transcription Factor NF-κB by Sesquiterpene Lactones from Podachaenium eminens, Planta Med. 66, 591-595.
-
(2000)
Planta Med.
, vol.66
, pp. 591-595
-
-
Castro, V.1
Murillo, R.2
Klaas, C.A.3
Meunier, C.4
Mora, G.5
Pahl, H.L.6
Merfort, I.7
-
70
-
-
0035015065
-
Immunosuppressive sesquiterpene alkaloids from Tripterygium wilfordii
-
Duan, H., Takaishi, Y., Momota, H., Ohmoto, Y., Taki, T., Jia, Y., and Li, D. (2001) Immunosuppressive Sesquiterpene Alkaloids from Tripterygium wilfordii, J. Nat. Prod. 64, 582-587.
-
(2001)
J. Nat. Prod.
, vol.64
, pp. 582-587
-
-
Duan, H.1
Takaishi, Y.2
Momota, H.3
Ohmoto, Y.4
Taki, T.5
Jia, Y.6
Li, D.7
-
71
-
-
0036853808
-
Daucane phytoestrogens: A structure-activity study
-
Appendino, G., Spagliardi, P., Cravotto, G., Pocock, V., and Milligan, S. (2002) Daucane Phytoestrogens: A Structure-Activity Study, J. Nat. Prod. 65, 1612-1615.
-
(2002)
J. Nat. Prod.
, vol.65
, pp. 1612-1615
-
-
Appendino, G.1
Spagliardi, P.2
Cravotto, G.3
Pocock, V.4
Milligan, S.5
-
72
-
-
10744220567
-
Antitumor agents. 228. Five new agarofurans, reissantins A-E, and cytotoxic principles from Reissantia buchananii
-
Chang, F.R., Hayashi, K., Chen, I.H., Liaw, C.C., Bastow, K.F., Nakanishi, Y., Nozaki, H., Cragg, G.M., Wu, Y.C., and Lee, K.H. (2003) Antitumor Agents. 228. Five New Agarofurans, Reissantins A-E, and Cytotoxic Principles from Reissantia buchananii, J. Nat. Prod. 66, 1416-1420.
-
(2003)
J. Nat. Prod.
, vol.66
, pp. 1416-1420
-
-
Chang, F.R.1
Hayashi, K.2
Chen, I.H.3
Liaw, C.C.4
Bastow, K.F.5
Nakanishi, Y.6
Nozaki, H.7
Cragg, G.M.8
Wu, Y.C.9
Lee, K.H.10
-
73
-
-
0037058636
-
Costunolide, a sesquiterpene lactone from Saussurea lappa, Inhibits the VEGFR KDR/Flk-1 signaling pathway
-
Jeong, S.J., Itokawa, T., Shibuya, M., Kuwano, M., Ono, M., Higuchi, R., and Miyamoto, T. (2002) Costunolide, a Sesquiterpene Lactone from Saussurea lappa, Inhibits the VEGFR KDR/Flk-1 Signaling Pathway, Cancer Lett. 187, 129-133.
-
(2002)
Cancer Lett.
, vol.187
, pp. 129-133
-
-
Jeong, S.J.1
Itokawa, T.2
Shibuya, M.3
Kuwano, M.4
Ono, M.5
Higuchi, R.6
Miyamoto, T.7
-
74
-
-
0034062563
-
Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii: A new class of potent anti-HIV agents
-
Duan, H., Takaishi, Y., Imakura, Y., Jia, Y., Li, D., Cosentino, L.M., and Lee, K.H. (2000) Sesquiterpene Alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii: A New Class of Potent Anti-HIV Agents, J. Nat. Prod. 63, 357-361.
-
(2000)
J. Nat. Prod.
, vol.63
, pp. 357-361
-
-
Duan, H.1
Takaishi, Y.2
Imakura, Y.3
Jia, Y.4
Li, D.5
Cosentino, L.M.6
Lee, K.H.7
-
75
-
-
0000248311
-
Studies on the biosynthesis of cholesterol: XIV. The origin of prenoic acids from allyl pyrophosphates in liver enzyme systems
-
Christophe, J., and Popják, G. (1961) Studies on the Biosynthesis of Cholesterol: XIV. The Origin of Prenoic Acids from Allyl Pyrophosphates in Liver Enzyme Systems, J. Lipid Res. 2, 244-257.
-
(1961)
J. Lipid Res.
, vol.2
, pp. 244-257
-
-
Christophe, J.1
Popják, G.2
-
76
-
-
0028035383
-
Characterization of two distinct allyl pyrophosphatase activities from rat liver microsomes
-
Bansal, V.S., and Vaidya, S. (1994) Characterization of Two Distinct Allyl Pyrophosphatase Activities from Rat Liver Microsomes, Arch. Biochem. Biophys. 315, 393-399.
-
(1994)
Arch. Biochem. Biophys.
, vol.315
, pp. 393-399
-
-
Bansal, V.S.1
Vaidya, S.2
-
77
-
-
0031239831
-
Farnesol as a regulator of HMG-CoA reductase degradation: Characterization and Role of farnesyl pyrophosphatase
-
Meigs, T.E., and Simoni, R.D. (1997) Farnesol as a Regulator of HMG-CoA Reductase Degradation: Characterization and Role of Farnesyl Pyrophosphatase, Arch. Biochem. Biophys. 345, 1-9.
-
(1997)
Arch. Biochem. Biophys.
, vol.345
, pp. 1-9
-
-
Meigs, T.E.1
Simoni, R.D.2
-
78
-
-
0000021535
-
Stereochemical studies of botryococcene biosynthesis: Analogies between 1′-1 and 1′-3 condensations in the isoprenoid pathway
-
Huang, Z., and Poulter, C.D. (1989) Stereochemical Studies of Botryococcene Biosynthesis: Analogies Between 1′-1 and 1′-3 Condensations in the Isoprenoid Pathway, J. Am. Chem. Soc. 111, 2713-2715.
-
(1989)
J. Am. Chem. Soc.
, vol.111
, pp. 2713-2715
-
-
Huang, Z.1
Poulter, C.D.2
-
79
-
-
0029020395
-
Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells
-
Crick, D.C., Andres, D.A., and Waechter, C.J. (1995) Farnesol Is Utilized for Protein Isoprenylation and the Biosynthesis of Cholesterol in Mammalian Cells, Biochem. Biophys. Res. Commun. 211, 590-599.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.211
, pp. 590-599
-
-
Crick, D.C.1
Andres, D.A.2
Waechter, C.J.3
-
80
-
-
0028991308
-
3H]farnesol to cholesterol and cholesterogenic intermediates in the living rat eye
-
3H]Farnesol to Cholesterol and Cholesterogenic Intermediates in the Living Rat Eye, Biochem. Biophys. Res. Commun. 210, 695-702.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.210
, pp. 695-702
-
-
Fliesler, S.J.1
Keller, R.K.2
-
81
-
-
0031584090
-
Metabolism of farnesol: Phosphorylation of farnesol by rat liver microsomal and peroxisomal fractions
-
Westfall, D., Aboushadi, N., Shackelford, J.E., and Krisans, S.K. (1997) Metabolism of Farnesol: Phosphorylation of Farnesol by Rat Liver Microsomal and Peroxisomal Fractions, Biochem. Biophys. Res. Commun. 230, 562-568.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.230
, pp. 562-568
-
-
Westfall, D.1
Aboushadi, N.2
Shackelford, J.E.3
Krisans, S.K.4
-
82
-
-
0030052970
-
Evidence for farnesol-mediated isoprenoid synthesis regulation in a halophilic archaeon, Haloferax volcanii
-
Tachibana, A., Tanaka, T., Taniguchi, M., and Oi, S. (1996) Evidence for Farnesol-Mediated Isoprenoid Synthesis Regulation in a Halophilic Archaeon, Haloferax volcanii, FEBS Lett. 379, 43-46.
-
(1996)
FEBS Lett.
, vol.379
, pp. 43-46
-
-
Tachibana, A.1
Tanaka, T.2
Taniguchi, M.3
Oi, S.4
-
83
-
-
0032524373
-
Phosphorylation of farnesol in rat liver microsomes: Properties of farnesol kinase and farnesyl phosphate kinase
-
Bentinger, M., Grunler, J., Peterson, E., Swiezewska, E., and Dallner, G. (1998) Phosphorylation of Farnesol in Rat Liver Microsomes: Properties of Farnesol Kinase and Farnesyl Phosphate Kinase, Arch. Biochem. Biophys. 353, 191-198.
-
(1998)
Arch. Biochem. Biophys.
, vol.353
, pp. 191-198
-
-
Bentinger, M.1
Grunler, J.2
Peterson, E.3
Swiezewska, E.4
Dallner, G.5
-
84
-
-
0033539526
-
Farnesol is utilized for isoprenoid biosynthesis in plant cells via farnesyl pyrophosphate formed by successive monophosphorylation reactions
-
Thai, L., Rush, J.S., Maul, J.E., Devarenne, T., Rodgers, D.L., Chappell, J., and Waechter, C.J. (1999) Farnesol Is Utilized for Isoprenoid Biosynthesis in Plant Cells via Farnesyl Pyrophosphate Formed by Successive Monophosphorylation Reactions, Proc. Natl. Acad. Sci. USA 96, 13080-13085.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13080-13085
-
-
Thai, L.1
Rush, J.S.2
Maul, J.E.3
Devarenne, T.4
Rodgers, D.L.5
Chappell, J.6
Waechter, C.J.7
-
85
-
-
0034634593
-
Phosphorylation of geranyl and farnesyl pyrophosphates by Nm23 proteins/nucleoside diphosphate kinases
-
Wagner, P.D., and Vu, N.D. (2000) Phosphorylation of Geranyl and Farnesyl Pyrophosphates by Nm23 Proteins/Nucleoside Diphosphate Kinases, J. Biol. Chem. 275, 35570-35576.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35570-35576
-
-
Wagner, P.D.1
Vu, N.D.2
-
86
-
-
0023874006
-
Isopentenoid synthesis in isolated embryonic drosophila cells. Farnesol catabolism and omega-oxidation
-
Gonzalez-Pacanowska, D., Arison, B., Havel, C.M., and Watson, J.A. (1988) Isopentenoid Synthesis in Isolated Embryonic Drosophila Cells. Farnesol Catabolism and Omega-Oxidation, J. Biol. Chem. 263, 1301-1306.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 1301-1306
-
-
Gonzalez-Pacanowska, D.1
Arison, B.2
Havel, C.M.3
Watson, J.A.4
-
87
-
-
0021051936
-
Metabolism of mevalonic acid in cell-free homogenates of bovine retinas. Formation of novel isoprenoid acids
-
Fliesler, S.J., and Schroepfer, G.J., Jr. (1983) Metabolism of Mevalonic Acid in Cell-Free Homogenates of Bovine Retinas. Formation of Novel Isoprenoid Acids, J. Biol. Chem. 258, 15062-15070.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 15062-15070
-
-
Fliesler, S.J.1
Schroepfer Jr., G.J.2
-
88
-
-
0025974055
-
Human liver alcohol dehydrogenases catalyze the oxidation of the intermediary alcohols of the shunt pathway of mevalonate metabolism
-
Keung, W.M. (1991) Human Liver Alcohol Dehydrogenases Catalyze the Oxidation of the Intermediary Alcohols of the Shunt Pathway of Mevalonate Metabolism, Biochem. Biophys. Res. Commun. 174, 701-707.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.174
, pp. 701-707
-
-
Keung, W.M.1
-
89
-
-
0030801368
-
Isolation and characterization of a prenylcysteine lyase from bovine brain
-
Zhang, L., Tschantz, W.R., and Casey, P.J. (1997) Isolation and Characterization of a Prenylcysteine Lyase from Bovine Brain, J. Biol. Chem. 272, 23354-23359.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23354-23359
-
-
Zhang, L.1
Tschantz, W.R.2
Casey, P.J.3
-
90
-
-
0030903764
-
Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol
-
Bostedor, R.G., Karkas, J.D., Arison, B.H., Bansal, V.S., Vaidya, S., Germershausen, J.I., Kurtz, M.M., and Bergstrom, J.D. (1997) Farnesol-Derived Dicarboxylic Acids in the Urine of Animals Treated with Zaragozic Acid A or with Farnesol, J. Biol. Chem. 272, 9197-9203.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9197-9203
-
-
Bostedor, R.G.1
Karkas, J.D.2
Arison, B.H.3
Bansal, V.S.4
Vaidya, S.5
Germershausen, J.I.6
Kurtz, M.M.7
Bergstrom, J.D.8
-
91
-
-
0032127143
-
Massive production of farnesol-derived dicarboxylic acids in mice treated with the squalene synthase inhibitor zaragozic acid A
-
Vaidya, S., Bostedor, R., Kurtz, M.M., Bergstrom, J.D., and Bansal, V.S. (1998) Massive Production of Farnesol-Derived Dicarboxylic Acids in Mice Treated with the Squalene Synthase Inhibitor Zaragozic Acid A, Arch. Biochem. Biophys. 355, 84-92.
-
(1998)
Arch. Biochem. Biophys.
, vol.355
, pp. 84-92
-
-
Vaidya, S.1
Bostedor, R.2
Kurtz, M.M.3
Bergstrom, J.D.4
Bansal, V.S.5
-
92
-
-
0020989036
-
Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta
-
Baker, F.C., Mauchamp, B., Tsai, L.W., and Schooley, D.A. (1983) Farnesol and Farnesal Dehydrogenase(s) in Corpora Allata of the Tobacco Hornworm Moth, Manduca sexta, J. Lipid Res. 24, 1586-1594.
-
(1983)
J. Lipid Res.
, vol.24
, pp. 1586-1594
-
-
Baker, F.C.1
Mauchamp, B.2
Tsai, L.W.3
Schooley, D.A.4
-
93
-
-
0000812012
-
Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver
-
Keller, R.K., Zhao, Z., Chambers, C., and Ness, G.C. (1996) Farnesol Is Not the Nonsterol Regulator Mediating Degradation of HMG-CoA Reductase in Rat Liver, Arch. Biochem. Biophys. 328, 324-330.
-
(1996)
Arch. Biochem. Biophys.
, vol.328
, pp. 324-330
-
-
Keller, R.K.1
Zhao, Z.2
Chambers, C.3
Ness, G.C.4
-
94
-
-
0033520286
-
Modulation of neuronal voltage-gated calcium channels by farnesol
-
Roullet, J.B., Spaetgens, R.L., Burlingame, T., Feng, Z.P., and Zamponi, G.W. (1999) Modulation of Neuronal Voltage-Gated Calcium Channels by Farnesol, J. Biol. Chem. 274, 25439-25446.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25439-25446
-
-
Roullet, J.B.1
Spaetgens, R.L.2
Burlingame, T.3
Feng, Z.P.4
Zamponi, G.W.5
-
95
-
-
0031260487
-
Determination of farnesyl pyrophosphate in dog and human plasma by high-performance liquid chromatography with fluorescence detection
-
Saisho, Y., Morimoto, A., and Umeda, T. (1997) Determination of Farnesyl Pyrophosphate in Dog and Human Plasma by High-Performance Liquid Chromatography with Fluorescence Detection, Anal. Biochem. 252, 89-95.
-
(1997)
Anal. Biochem.
, vol.252
, pp. 89-95
-
-
Saisho, Y.1
Morimoto, A.2
Umeda, T.3
-
96
-
-
0023678371
-
Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis
-
Bruenger, E., and Rilling, H.C. (1988) Determination of Isopentenyl Diphosphate and Farnesyl Diphosphate in Tissue Samples with a Comment on Secondary Regulation of Polyisoprenoid Biosynthesis, Anal. Biochem. 173, 321-327.
-
(1988)
Anal. Biochem.
, vol.173
, pp. 321-327
-
-
Bruenger, E.1
Rilling, H.C.2
-
97
-
-
0036290647
-
Farnesol as an inhibitor and substrate for rabbit liver microsomal P450 enzymes
-
Raner, G.M., Muir, A.Q., Lowry, C.W., and Davis, B.A. (2002) Farnesol as an Inhibitor and Substrate for Rabbit Liver Microsomal P450 Enzymes, Biochem. Biophys. Res. Commun. 293, 1-6.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 1-6
-
-
Raner, G.M.1
Muir, A.Q.2
Lowry, C.W.3
Davis, B.A.4
-
98
-
-
0019443302
-
Enzymic synthesis of juvenile hormone in locust corpora allata: Evidence for a microsomal cytochrome P-450 linked methyl farnesoate epoxidase
-
Feyereisen, R., Pratt, G.E., and Hamnett, A.F. (1981) Enzymic Synthesis of Juvenile Hormone in Locust Corpora Allata: Evidence for a Microsomal Cytochrome P-450 Linked Methyl Farnesoate Epoxidase, Eur. J. Biochem. 118, 231-238.
-
(1981)
Eur. J. Biochem.
, vol.118
, pp. 231-238
-
-
Feyereisen, R.1
Pratt, G.E.2
Hamnett, A.F.3
-
99
-
-
0031042230
-
Substrate specificity for the epoxidation of terpenoids and active site topology of house fly cytochrome P450 6A1
-
Andersen, J.F., Walding, J.K., Evans, P.H., Bowers, W.S., and Feyereisen, R. (1997) Substrate Specificity for the Epoxidation of Terpenoids and Active Site Topology of House Fly Cytochrome P450 6A1, Chem. Res. Toxicol. 10, 156-164.
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 156-164
-
-
Andersen, J.F.1
Walding, J.K.2
Evans, P.H.3
Bowers, W.S.4
Feyereisen, R.5
-
100
-
-
0032573065
-
A cytochrome P450 terpenoid hydroxylase linked to the suppression of insect juvenile hormone synthesis
-
Sutherland, T.D., Unnithan, G.C., Andersen, J.F., Evans, P.H., Murataliev, M.B., Szabo, L.Z., Mash, E.A., Bowers, W.S., and Feyereisen, R. (1998) A Cytochrome P450 Terpenoid Hydroxylase Linked to the Suppression of Insect Juvenile Hormone Synthesis, Proc. Nat. Acad. Sci. USA 95, 12884-12889.
-
(1998)
Proc. Nat. Acad. Sci. USA
, vol.95
, pp. 12884-12889
-
-
Sutherland, T.D.1
Unnithan, G.C.2
Andersen, J.F.3
Evans, P.H.4
Murataliev, M.B.5
Szabo, L.Z.6
Mash, E.A.7
Bowers, W.S.8
Feyereisen, R.9
-
102
-
-
0014010249
-
Feedback control of mevalonate synthesis by dietary cholesterol
-
Siperstein, M.D., and Fagan, V.M. (1966) Feedback Control of Mevalonate Synthesis by Dietary Cholesterol, J. Biol. Chem. 241, 602-609.
-
(1966)
J. Biol. Chem.
, vol.241
, pp. 602-609
-
-
Siperstein, M.D.1
Fagan, V.M.2
-
103
-
-
0017894322
-
Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase
-
Brown, M.S., Faust, J.R., and Goldstein, J.L. (1978) Induction of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity in Human Fibroblasts Incubated with Compactin (ML-236B), a Competitive Inhibitor of the Reductase, J. Biol. Chem. 253, 1121-1128.
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 1121-1128
-
-
Brown, M.S.1
Faust, J.R.2
Goldstein, J.L.3
-
104
-
-
0034809614
-
Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis
-
Sakakura, Y., Shimano, H., Sone, H., Takahashi, A., Inoue, N., Toyoshima, H., Suzuki, S., Yamada, N., and Inoue, K. (2001) Sterol Regulatory Element-Binding Proteins Induce an Entire Pathway of Cholesterol Synthesis, Biochem. Biophys. Res. Commun. 286, 176-183.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.286
, pp. 176-183
-
-
Sakakura, Y.1
Shimano, H.2
Sone, H.3
Takahashi, A.4
Inoue, N.5
Toyoshima, H.6
Suzuki, S.7
Yamada, N.8
Inoue, K.9
-
105
-
-
0026627805
-
Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 24(S),25-oxidolanosterol
-
Panini, S.R., Delate, T.A., and Sinensky, M. (1992) Post-transcriptional Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase by 24(S),25-Oxidolanosterol, J. Biol. Chem. 267, 12647-12654.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 12647-12654
-
-
Panini, S.R.1
Delate, T.A.2
Sinensky, M.3
-
106
-
-
0025816877
-
Genetic distinction between sterol-mediated transcriptional and posttranscriptional control of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
-
Dawson, P.A., Metherall, J.E., Ridgway, N.D., Brown, M.S., and Goldstein, J.L. (1991) Genetic Distinction Between Sterol-Mediated Transcriptional and Posttranscriptional Control of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase, J. Biol. Chem. 266, 9128-9134.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 9128-9134
-
-
Dawson, P.A.1
Metherall, J.E.2
Ridgway, N.D.3
Brown, M.S.4
Goldstein, J.L.5
-
107
-
-
0023902411
-
Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme
-
Nakanishi, M., Goldstein, J.L., and Brown, M.S. (1988) Multivalent Control of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase. Mevalonate-Derived Product Inhibits Translation of mRNA and Accelerates Degradation of Enzyme, J. Biol. Chem. 263, 8929-8937.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 8929-8937
-
-
Nakanishi, M.1
Goldstein, J.L.2
Brown, M.S.3
-
108
-
-
0026461126
-
Distinct sterol and nonsterol signals for the regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase
-
Roitelman, J., and Simoni, R.D. (1992) Distinct Sterol and Nonsterol Signals for the Regulated Degradation of 3-Hydroxy-3-methylglutaryl-CoA Reductase, J. Biol. Chem. 267, 25264-25273.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 25264-25273
-
-
Roitelman, J.1
Simoni, R.D.2
-
109
-
-
0028157541
-
Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl- coenzyme A reductase in vivo and in vitro
-
Correll, C.C., and Edwards, P.A. (1994) Mevalonic Acid-Dependent Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase in vivo and in vitro, J. Biol. Chem. 269, 633-638.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 633-638
-
-
Correll, C.C.1
Edwards, P.A.2
-
110
-
-
0028307290
-
Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
-
Correll, C.C., Ng, L., and Edwards, P.A. (1994) Identification of Farnesol as the Non-sterol Derivative of Mevalonic Acid Required for the Accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase, J. Biol. Chem. 269, 17390-17393.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17390-17393
-
-
Correll, C.C.1
Ng, L.2
Edwards, P.A.3
-
111
-
-
0028285272
-
Non-sterol compounds that regulate cholesterogenesis. Analogues of farnesyl pyrophosphate reduce 3-hydroxy-3-methylglutaryl-coenzyme A reductase levels
-
Bradfute, D.L., and Simoni, R.D. (1994) Non-sterol Compounds That Regulate Cholesterogenesis. Analogues of Farnesyl Pyrophosphate Reduce 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Levels, J. Biol. Chem. 269, 6645-6650.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6645-6650
-
-
Bradfute, D.L.1
Simoni, R.D.2
-
112
-
-
0027288196
-
Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
-
Parker, R.A., Pearce, B.C., Clark, R.W., Gordon, D.A., and Wright, J.J. (1993) Tocotrienols Regulate Cholesterol Production in Mammalian Cells by Post-transcriptional Suppression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase, J. Biol. Chem. 268, 11230-11238.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11230-11238
-
-
Parker, R.A.1
Pearce, B.C.2
Clark, R.W.3
Gordon, D.A.4
Wright, J.J.5
-
113
-
-
0033615648
-
A highly conserved signal controls degradation of 3-hydroxy-3- methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes
-
Gardner, R.G., and Hampton, R.Y. (1999) A Highly Conserved Signal Controls Degradation of 3-Hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) Reductase in Eukaryotes, J. Biol. Chem. 274, 31671-31678.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31671-31678
-
-
Gardner, R.G.1
Hampton, R.Y.2
-
114
-
-
0346101770
-
Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol
-
Sever, N., Song, B.L., Yabe, D., Goldstein, J.L., Brown, M.S., and DeBose-Boyd, R.A. (2003) Insig-Dependent Ubiquitination and Degradation of Mammalian 3-Hydroxy-3-methylglutaryl-CoA Reductase Stimulated by Sterols and Geranylgeraniol, J. Biol. Chem. 278, 52479-52490.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52479-52490
-
-
Sever, N.1
Song, B.L.2
Yabe, D.3
Goldstein, J.L.4
Brown, M.S.5
DeBose-Boyd, R.A.6
-
115
-
-
0037229435
-
Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at the post-transcriptional level
-
Peffley, D.M., and Gayen, A.K. (2003) Plant-Derived Monoterpenes Suppress Hamster Kidney Cell 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Synthesis at the Post-transcriptional Level, J. Nutr. 133, 38-44.
-
(2003)
J. Nutr.
, vol.133
, pp. 38-44
-
-
Peffley, D.M.1
Gayen, A.K.2
-
116
-
-
0037209307
-
Biochemistry and molecular biology of de novo isoprenoid pheromone production in the scolytidae
-
Seybold, S.J., and Tittiger, C. (2003) Biochemistry and Molecular Biology of de novo Isoprenoid Pheromone Production in the Scolytidae, Annu. Rev. Entomol. 48, 425-453.
-
(2003)
Annu. Rev. Entomol.
, vol.48
, pp. 425-453
-
-
Seybold, S.J.1
Tittiger, C.2
-
117
-
-
0036837292
-
Male Jeffrey pine beetle, Dendroctonus jeffreyi, synthesizes the pheromone component frontalin in anterior midgut tissue
-
Hall, G.M., Tittiger, C., Blomquist, G.J., Andrews, G.L., Mastick, G.S., Barkawi, L.S., Bengoa, C., and Seybold, S.J. (2002) Male Jeffrey Pine Beetle, Dendroctonus jeffreyi, Synthesizes the Pheromone Component Frontalin in Anterior Midgut Tissue, Insect Biochem. Mol. Biol. 32, 1525-1532.
-
(2002)
Insect Biochem. Mol. Biol.
, vol.32
, pp. 1525-1532
-
-
Hall, G.M.1
Tittiger, C.2
Blomquist, G.J.3
Andrews, G.L.4
Mastick, G.S.5
Barkawi, L.S.6
Bengoa, C.7
Seybold, S.J.8
-
118
-
-
0037474139
-
Structure and juvenile hormone-mediated regulation of the HMG-CoA reductase gene from the Jeffrey pine beetle, Dendroctonus jeffreyi
-
Tittiger, C., Barkawi, L.S., Bengoa, C.S., Blomquist, G.J., and Seybold, S.J. (2003) Structure and Juvenile Hormone-Mediated Regulation of the HMG-CoA Reductase Gene from the Jeffrey Pine Beetle, Dendroctonus jeffreyi, Mol. Cell. Endocrinol. 199, 11-21.
-
(2003)
Mol. Cell. Endocrinol.
, vol.199
, pp. 11-21
-
-
Tittiger, C.1
Barkawi, L.S.2
Bengoa, C.S.3
Blomquist, G.J.4
Seybold, S.J.5
-
119
-
-
0028289750
-
Regulation of HMG-CoA reductase activity in plants
-
Stermer, B.A., Bianchini, G.M., and Korth, K.L. (1994) Regulation of HMG-CoA Reductase Activity in Plants, J. Lipid Res. 35, 1133-1140.
-
(1994)
J. Lipid Res.
, vol.35
, pp. 1133-1140
-
-
Stermer, B.A.1
Bianchini, G.M.2
Korth, K.L.3
-
120
-
-
0036740929
-
Inhibition of squalene synthase and squalene epoxidase in tobacco cells triggers an up-regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase
-
Wentzinger, L.F., Bach, T.J., and Hartmann, M.A. (2002) Inhibition of Squalene Synthase and Squalene Epoxidase in Tobacco Cells Triggers an Up-regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase, Plant Physiol. 130, 334-346.
-
(2002)
Plant Physiol.
, vol.130
, pp. 334-346
-
-
Wentzinger, L.F.1
Bach, T.J.2
Hartmann, M.A.3
-
121
-
-
0033836968
-
Farnesol-induced cell death and stimulation of 3-hydroxy-3- methylglutaryl-coenzyme A reductase activity in tobacco cv bright yellow-2 cells
-
Hemmerlin, A., and Bach, T.J. (2000) Farnesol-Induced Cell Death and Stimulation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Activity in Tobacco cv Bright Yellow-2 Cells, Plant Physiol. 123, 1257-1268.
-
(2000)
Plant Physiol.
, vol.123
, pp. 1257-1268
-
-
Hemmerlin, A.1
Bach, T.J.2
-
122
-
-
0017055252
-
ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium
-
Endo, A., Kuroda, M., and Tsujita, Y. (1976) ML-236A, ML-236B, and ML-236C, New Inhibitors of Cholesterogenesis Produced by Penicillium citrinium, J. Antibiot. (Tokyo) 29, 1346-1348.
-
(1976)
J. Antibiot. (Tokyo)
, vol.29
, pp. 1346-1348
-
-
Endo, A.1
Kuroda, M.2
Tsujita, Y.3
-
123
-
-
0024316475
-
Genetic and pharmacological suppression of oncogenic mutations in RAS genes of yeast and humans
-
Schafer, W.R., Kim, R., Sterne, R., Thorner, J., Kim, S.H., and Rine, J. (1989) Genetic and Pharmacological Suppression of Oncogenic Mutations in RAS Genes of Yeast and Humans, Science 245, 379-385.
-
(1989)
Science
, vol.245
, pp. 379-385
-
-
Schafer, W.R.1
Kim, R.2
Sterne, R.3
Thorner, J.4
Kim, S.H.5
Rine, J.6
-
124
-
-
0025217828
-
Inhibition of isoprenoid biosynthesis and the post-translational modification of pro-p21
-
Leonard, S., Beck, L., and Sinensky, M. (1990) Inhibition of Isoprenoid Biosynthesis and the Post-translational Modification of pro-p21, J. Biol. Chem. 265, 5157-5160.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 5157-5160
-
-
Leonard, S.1
Beck, L.2
Sinensky, M.3
-
125
-
-
0037155865
-
Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, and RhoB
-
Holstein, S.A., Wohlford-Lenane, C.L., and Hohl, R.J. (2002) Consequences of Mevalonate Depletion. Differential Transcriptional, Translational, and Post-translational Up-regulation of Ras, Rap1a, RhoA, and RhoB, J. Biol. Chem. 277, 10678-10682.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10678-10682
-
-
Holstein, S.A.1
Wohlford-Lenane, C.L.2
Hohl, R.J.3
-
126
-
-
0032581391
-
Control of Rab5 and Rab7 expression by the isoprenoid pathway
-
Laezza, C., Bucci, C., Santillo, M., Bruni, C.B., and Bifulco, M. (1998) Control of Rab5 and Rab7 Expression by the Isoprenoid Pathway, Biochem. Biophys. Res. Commun. 248, 469-472.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.248
, pp. 469-472
-
-
Laezza, C.1
Bucci, C.2
Santillo, M.3
Bruni, C.B.4
Bifulco, M.5
-
127
-
-
0029079141
-
Control of RAS mRNA level by the mevalonate pathway
-
Dimster-Denk, D., Schafer, W.R., and Rine, J. (1995) Control of RAS mRNA Level by the Mevalonate Pathway, Mol. Biol. Cell. 6, 59-70.
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 59-70
-
-
Dimster-Denk, D.1
Schafer, W.R.2
Rine, J.3
-
128
-
-
0037137175
-
Isoprenoids influence the expression of Ras and Ras-related proteins
-
Holstein, S.A., Wohlford-Lenane, C.L., and Hohl, R.J. (2002) Isoprenoids Influence the Expression of Ras and Ras-Related Proteins, Biochemistry 41, 13698-13704.
-
(2002)
Biochemistry
, vol.41
, pp. 13698-13704
-
-
Holstein, S.A.1
Wohlford-Lenane, C.L.2
Hohl, R.J.3
-
129
-
-
0344059127
-
Isoprenoid pyrophosphate analogues regulate expression of Ras-related proteins
-
Holstein, S.A., Wohlford-Lenane, C.L., Wiemer, D.F., and Hohl, R.J. (2003) Isoprenoid Pyrophosphate Analogues Regulate Expression of Ras-Related Proteins, Biochemistry 42, 4384-4391.
-
(2003)
Biochemistry
, vol.42
, pp. 4384-4391
-
-
Holstein, S.A.1
Wohlford-Lenane, C.L.2
Wiemer, D.F.3
Hohl, R.J.4
-
130
-
-
0029046931
-
Identification of a nuclear receptor that is activated by farnesol metabolites
-
Forman, B.M., Goode, E., Chen, J., Oro, A.E., Bradley, D.J., Perlmann, T., Noonan, D.J., Burka, L.T., McMorris, T., Lamph, W.W., et al. (1995) Identification of a Nuclear Receptor That Is Activated by Farnesol Metabolites, Cell 81, 687-693.
-
(1995)
Cell
, vol.81
, pp. 687-693
-
-
Forman, B.M.1
Goode, E.2
Chen, J.3
Oro, A.E.4
Bradley, D.J.5
Perlmann, T.6
Noonan, D.J.7
Burka, L.T.8
McMorris, T.9
Lamph, W.W.10
-
131
-
-
0033026760
-
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
-
Wang, H., Chen, J., Hollister, K., Sowers, L.C., and Forman, B.M. (1999) Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR, Mol. Cell. 3, 543-553.
-
(1999)
Mol. Cell
, vol.3
, pp. 543-553
-
-
Wang, H.1
Chen, J.2
Hollister, K.3
Sowers, L.C.4
Forman, B.M.5
-
132
-
-
0033591387
-
Bile acids: Natural ligands for an orphan nuclear receptor
-
Parks, D.J., Blanchard, S.G., Bledsoe, R.K., Chandra, G., Consler, T.G., Kliewer, S.A., Stimmel, J.B., Willson, T.M., Zavacki, A.M., Moore, D.D., and Lehmann, J.M. (1999) Bile Acids: Natural Ligands for an Orphan Nuclear Receptor, Science 284, 1365-1368.
-
(1999)
Science
, vol.284
, pp. 1365-1368
-
-
Parks, D.J.1
Blanchard, S.G.2
Bledsoe, R.K.3
Chandra, G.4
Consler, T.G.5
Kliewer, S.A.6
Stimmel, J.B.7
Willson, T.M.8
Zavacki, A.M.9
Moore, D.D.10
Lehmann, J.M.11
-
133
-
-
0033591297
-
Identification of a nuclear receptor for bile acids
-
Makishima, M., Okamoto, A.Y., Repa, J.J., Tu, H., Learned, R.M., Luk, A., Hull, M.V., Lustig, K.D., Mangelsdorf, D.J., and Shan, B. (1999) Identification of a Nuclear Receptor for Bile Acids, Science 284, 1362-1365.
-
(1999)
Science
, vol.284
, pp. 1362-1365
-
-
Makishima, M.1
Okamoto, A.Y.2
Repa, J.J.3
Tu, H.4
Learned, R.M.5
Luk, A.6
Hull, M.V.7
Lustig, K.D.8
Mangelsdorf, D.J.9
Shan, B.10
-
134
-
-
0040952982
-
Farnesol stimulates differentiation in epidermal keratinocytes via PPARα
-
Hanley, K., Komuves, L.G., Ng, D.C., Schoonjans, K., He, S.S., Lau, P., Bikle, D.D., Williams, M.L., Elias, P.M., Auwerx, J., and Feingold, K.R. (2000) Farnesol Stimulates Differentiation in Epidermal Keratinocytes via PPARα, J. Biol. Chem. 275, 11484-11491.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 11484-11491
-
-
Hanley, K.1
Komuves, L.G.2
Ng, D.C.3
Schoonjans, K.4
He, S.S.5
Lau, P.6
Bikle, D.D.7
Williams, M.L.8
Elias, P.M.9
Auwerx, J.10
Feingold, K.R.11
-
135
-
-
0027344197
-
Retinoid receptors
-
Mangelsdorf, D.J., Kliewer, S.A., Kakizuka, A., Umesono, K., and Evans, R.M. (1993) Retinoid Receptors, Recent Prog. Horm. Res. 48, 99-121.
-
(1993)
Recent Prog. Horm. Res.
, vol.48
, pp. 99-121
-
-
Mangelsdorf, D.J.1
Kliewer, S.A.2
Kakizuka, A.3
Umesono, K.4
Evans, R.M.5
-
136
-
-
0029044946
-
Activation of mammalian retinoid X receptors by the insect growth regulator methoprene
-
Harmon, M.A., Boehm, M.F., Heyman, R.A., and Mangelsdorf, D.J. (1995) Activation of Mammalian Retinoid X Receptors by the Insect Growth Regulator Methoprene, Proc. Natl. Acad. Sci. USA 92, 6157-6160.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6157-6160
-
-
Harmon, M.A.1
Boehm, M.F.2
Heyman, R.A.3
Mangelsdorf, D.J.4
-
137
-
-
0035966125
-
Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate
-
Gan, X., Kaplan, R., Menke, J.G., MacNaul, K., Chen, Y., Sparrow, C.P., Zhou, G., Wright, S.D., and Cai, T.Q. (2001) Dual Mechanisms of ABCA1 Regulation by Geranylgeranyl Pyrophosphate, J. Biol. Chem. 276, 48702-48708.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48702-48708
-
-
Gan, X.1
Kaplan, R.2
Menke, J.G.3
MacNaul, K.4
Chen, Y.5
Sparrow, C.P.6
Zhou, G.7
Wright, S.D.8
Cai, T.Q.9
-
138
-
-
0033968452
-
Preferential induction of apoptosis of leukaemic cells by farnesol
-
Rioja, A., Pizzey, A.R., Marson, C.M., and Thomas, N.S. (2000) Preferential Induction of Apoptosis of Leukaemic Cells by Farnesol, FEBS. Lett. 467, 291-295.
-
(2000)
FEBS. Lett.
, vol.467
, pp. 291-295
-
-
Rioja, A.1
Pizzey, A.R.2
Marson, C.M.3
Thomas, N.S.4
-
139
-
-
0029143223
-
Mechanism of farnesol cytotoxicity: Further evidence for the role of PKC-dependent signal transduction in farnesol-induced apoptotic cell death
-
Voziyan, P.A., Haug, J.S., and Melnykovych, G. (1995) Mechanism of Farnesol Cytotoxicity: Further Evidence for the Role of PKC-Dependent Signal Transduction in Farnesol-Induced Apoptotic Cell Death, Biochem. Biophys. Res. Commun. 212, 479-486.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.212
, pp. 479-486
-
-
Voziyan, P.A.1
Haug, J.S.2
Melnykovych, G.3
-
140
-
-
0032518762
-
Dihydroheptaprenyl and dihydrodecaprenyl monophosphates induce apoptosis mediated by activation of caspase-3-like protease
-
Yasugi, E., Nakata, K., Yokoyama, Y., Kano, K., Dohi, T., and Oshima, M. (1998) Dihydroheptaprenyl and Dihydrodecaprenyl Monophosphates Induce Apoptosis Mediated by Activation of Caspase-3-like Protease, Biochim. Biophys. Acta 1389, 132-140.
-
(1998)
Biochim. Biophys. Acta
, vol.1389
, pp. 132-140
-
-
Yasugi, E.1
Nakata, K.2
Yokoyama, Y.3
Kano, K.4
Dohi, T.5
Oshima, M.6
-
141
-
-
0032476029
-
Competitive inhibition of choline phosphotransferase by geranylgeraniol and farnesol inhibits phosphatidylcholine synthesis and induces apoptosis in human lung adenocarcinoma A549 cells
-
Miquel, K., Pradines, A., Terce, F., Selmi, S., and Favre, G. (1998) Competitive Inhibition of Choline Phosphotransferase by Geranylgeraniol and Farnesol Inhibits Phosphatidylcholine Synthesis and Induces Apoptosis in Human Lung Adenocarcinoma A549 Cells, J. Biol. Chem. 273, 26179-26186.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26179-26186
-
-
Miquel, K.1
Pradines, A.2
Terce, F.3
Selmi, S.4
Favre, G.5
-
142
-
-
0031056450
-
Inhibition of pancreatic cancer growth by the dietary isoprenoids farnesol and geraniol
-
Burke, Y.D., Stark, M.J., Roach, S.L., Sen, S.E., and Crowell, P.L. (1997) Inhibition of Pancreatic Cancer Growth by the Dietary Isoprenoids Farnesol and Geraniol, Lipids 32, 151-156.
-
(1997)
Lipids
, vol.32
, pp. 151-156
-
-
Burke, Y.D.1
Stark, M.J.2
Roach, S.L.3
Sen, S.E.4
Crowell, P.L.5
-
143
-
-
0031721764
-
Farnesol-induced generation of reactive oxygen species via indirect inhibition of the mitochondrial electron transport chain in the yeast Saccharomyces cerevisiae
-
Machida, K., Tanaka, T., Fujita, K., and Taniguchi, M. (1998) Farnesol-Induced Generation of Reactive Oxygen Species via Indirect Inhibition of the Mitochondrial Electron Transport Chain in the Yeast Saccharomyces cerevisiae, J. Bacteriol. 180, 4460-4465.
-
(1998)
J. Bacteriol.
, vol.180
, pp. 4460-4465
-
-
Machida, K.1
Tanaka, T.2
Fujita, K.3
Taniguchi, M.4
-
144
-
-
0027496247
-
Farnesol inhibits phosphatidylcholine biosynthesis in cultured cells by decreasing cholinephosphotransferase activity
-
Voziyan, P.A., Goldner, C.M., and Melnykovych, G. (1993) Farnesol Inhibits Phosphatidylcholine Biosynthesis in Cultured Cells by Decreasing Cholinephosphotransferase Activity, Biochem. J. 295, 757-762.
-
(1993)
Biochem. J.
, vol.295
, pp. 757-762
-
-
Voziyan, P.A.1
Goldner, C.M.2
Melnykovych, G.3
-
145
-
-
0035816579
-
Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis
-
Wright, M.M., Henneberry, A.L., Lagace, T.A., Ridgway, N.D., and McMaster, C.R. (2001) Uncoupling Farnesol-Induced Apoptosis from Its Inhibition of Phosphatidylcholine Synthesis, J. Biol. Chem. 276, 25254-25261.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25254-25261
-
-
Wright, M.M.1
Henneberry, A.L.2
Lagace, T.A.3
Ridgway, N.D.4
McMaster, C.R.5
-
146
-
-
0028832005
-
Selective farnesol toxicity and translocation of protein kinase C in neoplastic HeLa-S3K and non-neoplastic CF-3 cells
-
Yazlovitskaya, E.M., and Melnykovych, G. (1995) Selective Farnesol Toxicity and Translocation of Protein Kinase C in Neoplastic HeLa-S3K and Non-neoplastic CF-3 Cells, Cancer Lett. 88, 179-183.
-
(1995)
Cancer Lett.
, vol.88
, pp. 179-183
-
-
Yazlovitskaya, E.M.1
Melnykovych, G.2
-
147
-
-
0032759103
-
Farnesol-induced generation of reactive oxygen species dependent on mitochondrial transmembrane potential hyperpolarization mediated by F(0)F(1)-ATPase in yeast
-
Machida, K., and Tanaka, T. (1999) Farnesol-Induced Generation of Reactive Oxygen Species Dependent on Mitochondrial Transmembrane Potential Hyperpolarization Mediated by F(0)F(1)-ATPase in Yeast, FEBS Lett. 462, 108-112.
-
(1999)
FEBS Lett.
, vol.462
, pp. 108-112
-
-
Machida, K.1
Tanaka, T.2
-
148
-
-
0034979081
-
A new dehydrogeranylgeraniol antioxidant from Saururus cernuus that inhibits intracellular reactive oxygen species (ROS)-catalyzed oxidation within HL-60 cells
-
Rajbhandari, I., Takamatsu, S., and Nagle, D.G. (2001) A New Dehydrogeranylgeraniol Antioxidant from Saururus cernuus That Inhibits Intracellular Reactive Oxygen Species (ROS)-Catalyzed Oxidation Within HL-60 Cells, J. Nat. Prod. 64, 693-695.
-
(2001)
J. Nat. Prod.
, vol.64
, pp. 693-695
-
-
Rajbhandari, I.1
Takamatsu, S.2
Nagle, D.G.3
-
149
-
-
0029931495
-
Farnesyl analogues inhibit vasoconstriction in animal and human arteries
-
Roullet, J.B., Xue, H., Chapman, J., McDougal, P., Roullet, C.M., and McCarron, D.A. (1996) Farnesyl Analogues Inhibit Vasoconstriction in Animal and Human Arteries, J. Clin. Invest. 97, 2384-2390.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2384-2390
-
-
Roullet, J.B.1
Xue, H.2
Chapman, J.3
McDougal, P.4
Roullet, C.M.5
McCarron, D.A.6
-
150
-
-
0031466230
-
2+ channels in vascular smooth muscle cells
-
2+ Channels in Vascular Smooth Muscle Cells, J. Biol. Chem. 272, 32240-32246.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32240-32246
-
-
Roullet, J.B.1
Luft, U.C.2
Xue, H.3
Chapman, J.4
Bychkov, R.5
Roullet, C.M.6
Luft, F.C.7
Haller, H.8
McCarron, D.A.9
-
151
-
-
0035836681
-
Purification and characterization of an autoregulatory substance capable of regulating the morphological transition in Candida albicans
-
Oh, K.B., Miyazawa, H., Naito, T., and Matsuoka, H. (2001) Purification and Characterization of an Autoregulatory Substance Capable of Regulating the Morphological Transition in Candida albicans, Proc. Natl. Acad. Sci. USA 98, 4664-4668.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4664-4668
-
-
Oh, K.B.1
Miyazawa, H.2
Naito, T.3
Matsuoka, H.4
-
152
-
-
0037170796
-
Evaluation of morphogenic regulatory activity of farnesoic acid and its derivatives against Candida albicans dimorphism
-
Kim, S., Kim, E., Shin, D.S., Kang, H., and Oh, K.B. (2002) Evaluation of Morphogenic Regulatory Activity of Farnesoic Acid and Its Derivatives Against Candida albicans Dimorphism, Bioorg. Med. Chem. Lett. 12, 895-898.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 895-898
-
-
Kim, S.1
Kim, E.2
Shin, D.S.3
Kang, H.4
Oh, K.B.5
-
153
-
-
0035406382
-
Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol
-
Hornby, J.M., Jensen, E.C., Lisec, A.D., Tasto, J.J., Jahnke, B., Shoemaker, R., Dussault, P., and Nickerson, K.W. (2001) Quorum Sensing in the Dimorphic Fungus Candida albicans Is Mediated by Farnesol, Appl. Environ. Microbiol. 67, 2982-2992.
-
(2001)
Appl. Environ. Microbiol.
, vol.67
, pp. 2982-2992
-
-
Hornby, J.M.1
Jensen, E.C.2
Lisec, A.D.3
Tasto, J.J.4
Jahnke, B.5
Shoemaker, R.6
Dussault, P.7
Nickerson, K.W.8
-
154
-
-
0038650921
-
Farnesol biosynthesis in Candida albicans: Cellular response to sterol inhibition by Zaragozic acid B
-
Hornby, J.M., Kebaara, B.W., and Nickerson, K.W. (2003) Farnesol Biosynthesis in Candida albicans: Cellular Response to Sterol Inhibition by Zaragozic Acid B, Antimicrob. Agents Chemother. 47, 2366-2369.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 2366-2369
-
-
Hornby, J.M.1
Kebaara, B.W.2
Nickerson, K.W.3
-
155
-
-
0036840116
-
Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule
-
Ramage, G., Saville, S.P., Wickes, B.L., and Lopez-Ribot, J.L. (2002) Inhibition of Candida albicans Biofilm Formation by Farnesol, a Quorum-Sensing Molecule, Appl. Environ. Microbiol. 68, 5459-5463.
-
(2002)
Appl. Environ. Microbiol.
, vol.68
, pp. 5459-5463
-
-
Ramage, G.1
Saville, S.P.2
Wickes, B.L.3
Lopez-Ribot, J.L.4
-
156
-
-
0029903276
-
In-vitro and in-vivo antibacterial activity of plaunotol, a cytoprotective antiulcer agent, against Helicobacter pylori
-
Koga, T., Kawada, H., Utsui, Y., Domon, H., Ishii, C., and Yasuda, H. (1996) In-vitro and in-vivo Antibacterial Activity of Plaunotol, a Cytoprotective Antiulcer Agent, Against Helicobacter pylori, J. Antimicrob. Chemother. 37, 919-929.
-
(1996)
J. Antimicrob. Chemother.
, vol.37
, pp. 919-929
-
-
Koga, T.1
Kawada, H.2
Utsui, Y.3
Domon, H.4
Ishii, C.5
Yasuda, H.6
-
157
-
-
0037309638
-
Antifungal diterpenes from hypoestes serpens (Acanthaceae)
-
Rasoamiaranjanahary, L., Marston, A., Guilet, D., Schenk, K., Randimbivololona, F., and Hostettmann, K. (2003) Antifungal Diterpenes from Hypoestes serpens (Acanthaceae), Phytochemistry 62, 333-337.
-
(2003)
Phytochemistry
, vol.62
, pp. 333-337
-
-
Rasoamiaranjanahary, L.1
Marston, A.2
Guilet, D.3
Schenk, K.4
Randimbivololona, F.5
Hostettmann, K.6
-
158
-
-
2642529526
-
In vitro antileishmanial effects of antibacterial diterpenes from two ethiopian Premna species: P. schimperi and P. oligotricha
-
Habtemariam, S. (2003) In vitro Antileishmanial Effects of Antibacterial Diterpenes from Two Ethiopian Premna Species: P. schimperi and P. oligotricha, BMC Pharmacol. 3, 6.
-
(2003)
BMC Pharmacol.
, vol.3
, pp. 6
-
-
Habtemariam, S.1
-
159
-
-
0035914101
-
Probing sponge-derived terpenoids for human 15-lipoxygenase inhibitors
-
Carroll, J., Jonsson, E.N., Ebel, R., Hartman, M.S., Holman, T.R., and Crews, P. (2001) Probing Sponge-Derived Terpenoids for Human 15-Lipoxygenase Inhibitors, J. Org. Chem. 66, 6847-6851.
-
(2001)
J. Org. Chem.
, vol.66
, pp. 6847-6851
-
-
Carroll, J.1
Jonsson, E.N.2
Ebel, R.3
Hartman, M.S.4
Holman, T.R.5
Crews, P.6
-
160
-
-
0036899026
-
Insect antifeedant activity of clerodane diterpenes and related model compounds
-
Klein Gebbinck, E.A., Jansen, B.J., and de Groot, A. (2002) Insect Antifeedant Activity of Clerodane Diterpenes and Related Model Compounds, Phytochemistry 61, 737-770.
-
(2002)
Phytochemistry
, vol.61
, pp. 737-770
-
-
Klein Gebbinck, E.A.1
Jansen, B.J.2
De Groot, A.3
-
161
-
-
0035666449
-
Blood glucose- and triglyceride-lowering effect of trans-dehydrocrotonin, a diterpene from Croton cajucara Benth., in rats
-
Silva, R.M., Santos, F.A., Rao, V.S., Maciel, M.A., and Pinto, A.C. (2001) Blood Glucose- and Triglyceride-Lowering Effect of trans-Dehydrocrotonin, a Diterpene from Croton cajucara Benth., in Rats, Diabetes Obes. Metab. 3, 452-456.
-
(2001)
Diabetes Obes. Metab.
, vol.3
, pp. 452-456
-
-
Silva, R.M.1
Santos, F.A.2
Rao, V.S.3
Maciel, M.A.4
Pinto, A.C.5
-
162
-
-
0034939302
-
Anti-tumor promoting diterpenes from the stem bark of Thuja standishii (Cupressaceae)
-
Iwamoto, M., Ohtsu, H., Tokuda, H., Nishino, H., Matsunaga, S., and Tanaka, R. (2001) Anti-tumor Promoting Diterpenes from the Stem Bark of Thuja standishii (Cupressaceae), Bioorg. Med. Chem. 9, 1911-1921.
-
(2001)
Bioorg. Med. Chem.
, vol.9
, pp. 1911-1921
-
-
Iwamoto, M.1
Ohtsu, H.2
Tokuda, H.3
Nishino, H.4
Matsunaga, S.5
Tanaka, R.6
-
163
-
-
0036198699
-
Farnesol and geranylgeraniol: Prevention and reversion of lovastatin-induced effects in NIH3T3 cells
-
Ownby, S.E., and Hohl, R.J. (2002) Farnesol and Geranylgeraniol: Prevention and Reversion of Lovastatin-Induced Effects in NIH3T3 Cells, Lipids 37, 185-192.
-
(2002)
Lipids
, vol.37
, pp. 185-192
-
-
Ownby, S.E.1
Hohl, R.J.2
-
164
-
-
0029985373
-
Identification and characterization of geranylgeraniol kinase and geranylgeranyl phosphate kinase from the archaebacterium Sulfolobus acidocaldarius
-
Ohnuma, S., Watanabe, M., and Nishino, T. (1996) Identification and Characterization of Geranylgeraniol Kinase and Geranylgeranyl Phosphate Kinase from the Archaebacterium Sulfolobus acidocaldarius, J. Biochem. (Tokyo) 119, 541-547.
-
(1996)
J. Biochem. (Tokyo)
, vol.119
, pp. 541-547
-
-
Ohnuma, S.1
Watanabe, M.2
Nishino, T.3
-
165
-
-
0036684886
-
Formation of (R)-2,3-dihydrogeranylgeranoic acid from geranylgeraniol in rat thymocytes
-
Kodaira, Y., Usui, K., Kon, I., and Sagami, H. (2002) Formation of (R)-2,3-Dihydrogeranylgeranoic Acid from Geranylgeraniol in Rat Thymocytes, J. Biochem. (Tokyo) 132, 327-334.
-
(2002)
J. Biochem. (Tokyo)
, vol.132
, pp. 327-334
-
-
Kodaira, Y.1
Usui, K.2
Kon, I.3
Sagami, H.4
-
166
-
-
0036133347
-
Effects of geranylgeranoic acid in bone: Induction of osteoblast differentiation and inhibition of osteoclast formation
-
Wang, X., Wu, J., Shidoji, Y., Muto, Y., Ohishi, N., Yagi, K., Ikegami, S., Shinki, T., Udagawa, N., Suda, T., and Ishimi, Y. (2002) Effects of Geranylgeranoic Acid in Bone: Induction of Osteoblast Differentiation and Inhibition of Osteoclast Formation, J. Bone Miner. Res. 17, 91-100.
-
(2002)
J. Bone Miner. Res.
, vol.17
, pp. 91-100
-
-
Wang, X.1
Wu, J.2
Shidoji, Y.3
Muto, Y.4
Ohishi, N.5
Yagi, K.6
Ikegami, S.7
Shinki, T.8
Udagawa, N.9
Suda, T.10
Ishimi, Y.11
-
168
-
-
0023176478
-
Identification of urinary and microsomal metabolites of geranylgeranylacetone in rats
-
Nishizawa, Y., Abe, S., Yamada, K., Nakamura, T., Yamatsu, I., and Kinoshita, K. (1987) Identification of Urinary and Microsomal Metabolites of Geranylgeranylacetone in Rats, Xenobiotica 17, 575-584.
-
(1987)
Xenobiotica
, vol.17
, pp. 575-584
-
-
Nishizawa, Y.1
Abe, S.2
Yamada, K.3
Nakamura, T.4
Yamatsu, I.5
Kinoshita, K.6
-
169
-
-
0028855473
-
Geranylgeraniol is a potent inducer of apoptosis in tumor cells
-
Ohizumi, H., Masuda, Y., Nakajo, S., Sakai, I., Ohsawa, S., and Nakaya, K. (1995) Geranylgeraniol Is a Potent Inducer of Apoptosis in Tumor Cells, J. Biochem. (Tokyo) 117, 11-13.
-
(1995)
J. Biochem. (Tokyo)
, vol.117
, pp. 11-13
-
-
Ohizumi, H.1
Masuda, Y.2
Nakajo, S.3
Sakai, I.4
Ohsawa, S.5
Nakaya, K.6
-
170
-
-
0034792075
-
Geranylgeraniol, an intermediate product in mevalonate pathway, induces apoptotic cell death in human hepatoma cells: Death receptor-independent activation of caspase-8 with down-regulation of Bcl-xL expression
-
Takeda, Y., Nakao, K., Nakata, K., Kawakami, A., Ida, H., Ichikawa, T., Shigeno, M., Kajiya, Y., Hamasaki, K., Kato, Y., and Eguchi, K. (2001) Geranylgeraniol, an Intermediate Product in Mevalonate Pathway, Induces Apoptotic Cell Death in Human Hepatoma Cells: Death Receptor-Independent Activation of Caspase-8 with Down-Regulation of Bcl-xL Expression, Jpn. J. Cancer Res. 92, 918-925.
-
(2001)
Jpn. J. Cancer Res.
, vol.92
, pp. 918-925
-
-
Takeda, Y.1
Nakao, K.2
Nakata, K.3
Kawakami, A.4
Ida, H.5
Ichikawa, T.6
Shigeno, M.7
Kajiya, Y.8
Hamasaki, K.9
Kato, Y.10
Eguchi, K.11
-
171
-
-
0031550232
-
Rapid loss in the mitochondrial membrane potential during geranylgeranoic acid-induced apoptosis
-
Shidoji, Y., Nakamura, N., Moriwaki, H., and Muto, Y. (1997) Rapid Loss in the Mitochondrial Membrane Potential During Geranylgeranoic Acid-Induced Apoptosis, Biochem. Biophys. Res. Commun. 230, 58-63.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.230
, pp. 58-63
-
-
Shidoji, Y.1
Nakamura, N.2
Moriwaki, H.3
Muto, Y.4
-
172
-
-
0036254464
-
Acyclo-retinoic acid induces apoptosis in human prostate cancer cells
-
Kotake-Nara, E., Kim, S.J., Kobori, M., Miyashita, K., and Nagao, A. (2002) Acyclo-Retinoic Acid Induces Apoptosis in Human Prostate Cancer Cells, Anticancer Res. 22, 689-695.
-
(2002)
Anticancer Res.
, vol.22
, pp. 689-695
-
-
Kotake-Nara, E.1
Kim, S.J.2
Kobori, M.3
Miyashita, K.4
Nagao, A.5
-
173
-
-
0030600384
-
Geranylgeraniol causes a decrease in levels of calreticulin and tyrosine phosphorylation of a 36-kDa protein prior to the appearance of apoptotic features in HL-60 cells
-
Nakajo, S., Okamoto, M., Masuda, Y., Sakai, I., Ohsawa, S., and Nakaya, K. (1996) Geranylgeraniol Causes a Decrease in Levels of Calreticulin and Tyrosine Phosphorylation of a 36-kDa Protein Prior to the Appearance of Apoptotic Features in HL-60 Cells, Biochem. Biophys. Res. Commun. 226, 741-745.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.226
, pp. 741-745
-
-
Nakajo, S.1
Okamoto, M.2
Masuda, Y.3
Sakai, I.4
Ohsawa, S.5
Nakaya, K.6
-
174
-
-
0031589963
-
Geranylgeraniol potently induces caspase-3-like activity during apoptosis in human leukemia U937 cells
-
Masuda, Y., Nakaya, M., Nakajo, S., and Nakaya, K. (1997) Geranylgeraniol Potently Induces Caspase-3-Like Activity During Apoptosis in Human Leukemia U937 Cells, Biochem. Biophys. Res. Commun. 234, 641-645.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.234
, pp. 641-645
-
-
Masuda, Y.1
Nakaya, M.2
Nakajo, S.3
Nakaya, K.4
-
175
-
-
0033730298
-
The mechanism of geranylgeraniol-induced apoptosis involves activation, by a caspase-3-like protease, of a c-jun N-terminal kinase signaling cascade and differs from mechanisms of apoptosis induced by conventional chemotherapeutic drugs
-
Masuda, Y., Nakaya, M., Aiuchi, T., Hashimoto, S., Nakajo, S., and Nakaya, K. (2000) The Mechanism of Geranylgeraniol-Induced Apoptosis Involves Activation, by a Caspase-3-like Protease, of a c-jun N-Terminal Kinase Signaling Cascade and Differs from Mechanisms of Apoptosis Induced by Conventional Chemotherapeutic Drugs, Leuk. Res. 24, 937-950.
-
(2000)
Leuk. Res.
, vol.24
, pp. 937-950
-
-
Masuda, Y.1
Nakaya, M.2
Aiuchi, T.3
Hashimoto, S.4
Nakajo, S.5
Nakaya, K.6
-
176
-
-
0030069102
-
Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-α
-
Nakamura, N., Shidoji, Y., Moriwaki, H., and Muto, Y. (1996) Apoptosis in Human Hepatoma Cell Line Induced by 4,5-Didehydro Geranylgeranoic Acid (acyclic retinoid) via Down-Regulation of Transforming Growth Factor-α, Biochem. Biophys. Res. Commun. 219, 100-104.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.219
, pp. 100-104
-
-
Nakamura, N.1
Shidoji, Y.2
Moriwaki, H.3
Muto, Y.4
-
177
-
-
0019508881
-
Antiulcer effect of geranylgeranylacetone, a new acyclic polyisoprenoid, on experimentally induced gastric and duodenal ulcers in rats
-
Murakami, M., Oketani, K., Fujisaki, H., Wakabayashi, T., and Ohgo, T. (1981) Antiulcer Effect of Geranylgeranylacetone, a New Acyclic Polyisoprenoid, on Experimentally Induced Gastric and Duodenal Ulcers in Rats, Arzneimittelforschung. 31, 799-804.
-
(1981)
Arzneimittelforschung
, vol.31
, pp. 799-804
-
-
Murakami, M.1
Oketani, K.2
Fujisaki, H.3
Wakabayashi, T.4
Ohgo, T.5
-
178
-
-
0022618659
-
Geranylgeranylacetone, a novel anti-ulcer drug, stimulates mucus synthesis and secretion in rat gastric cultured cells
-
Terano, A., Hiraishi, H., Ota, S., and Sugimoto, T. (1986) Geranylgeranylacetone, a Novel Anti-ulcer Drug, Stimulates Mucus Synthesis and Secretion in Rat Gastric Cultured Cells, Digestion 33, 206-210.
-
(1986)
Digestion
, vol.33
, pp. 206-210
-
-
Terano, A.1
Hiraishi, H.2
Ota, S.3
Sugimoto, T.4
-
179
-
-
0036918371
-
Suppression of Helicobacter pylori-induced interleukin-8 production in gastric cancer cell lines by an anti-ulcer drug, geranylgeranylacetone
-
Yoshimura, N., Suzuki, Y., and Saito, Y. (2002) Suppression of Helicobacter pylori-Induced Interleukin-8 Production in Gastric Cancer Cell Lines by an Anti-ulcer Drug, Geranylgeranylacetone, J. Gastroenterol. Hepatol. 17, 1153-1160.
-
(2002)
J. Gastroenterol. Hepatol.
, vol.17
, pp. 1153-1160
-
-
Yoshimura, N.1
Suzuki, Y.2
Saito, Y.3
-
180
-
-
0032833875
-
Geranylgeranylacetone suppresses spontaneous apoptotic DNA fragmentation in cultured guinea pig gastric pit cells
-
Tsutsumi, S., Rokutan, K., Tsuchiya, T., and Mizushima, T. (1999) Geranylgeranylacetone Suppresses Spontaneous Apoptotic DNA Fragmentation in Cultured Guinea Pig Gastric Pit Cells, Biol. Pharm. Bull. 22, 886-887.
-
(1999)
Biol. Pharm. Bull.
, vol.22
, pp. 886-887
-
-
Tsutsumi, S.1
Rokutan, K.2
Tsuchiya, T.3
Mizushima, T.4
-
181
-
-
0030038266
-
Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa
-
Hirakawa, T., Rokutan, K., Nikawa, T., and Kishi, K. (1996) Geranylgeranylacetone Induces Heat Shock Proteins in Cultured Guinea Pig Gastric Mucosal Cells and Rat Gastric Mucosa, Gastroenterology 111, 345-357.
-
(1996)
Gastroenterology
, vol.111
, pp. 345-357
-
-
Hirakawa, T.1
Rokutan, K.2
Nikawa, T.3
Kishi, K.4
-
182
-
-
0033665132
-
Induction of heat shock protein-70 (hsp-70) by intraarterial administration of geranylgeranylacetone
-
Tsuruma, T., Yagihashi, A., Hirata, K., Araya, J., Katsuramaki, T., Tarumi, K., Yanai, Y., and Watanabe, N. (2000) Induction of Heat Shock Protein-70 (hsp-70) by Intraarterial Administration of Geranylgeranylacetone, Transplant. Proc. 32, 1631-1633.
-
(2000)
Transplant. Proc.
, vol.32
, pp. 1631-1633
-
-
Tsuruma, T.1
Yagihashi, A.2
Hirata, K.3
Araya, J.4
Katsuramaki, T.5
Tarumi, K.6
Yanai, Y.7
Watanabe, N.8
-
183
-
-
0142059091
-
Astroglial activation accompanies heat shock protein upregulation in rat brain following single oral dose of geranylgeranylacetone
-
Fujiki, M., Kobayashi, H., Abe, T., and Ishii, K. (2003) Astroglial Activation Accompanies Heat Shock Protein Upregulation in Rat Brain Following Single Oral Dose of Geranylgeranylacetone, Brain Res. 991, 254-257.
-
(2003)
Brain Res.
, vol.991
, pp. 254-257
-
-
Fujiki, M.1
Kobayashi, H.2
Abe, T.3
Ishii, K.4
-
184
-
-
1142298658
-
Retinal ganglion cell protection with geranylgeranylacetone, a heat shock protein inducer, in a rat glaucoma model
-
Caprioli, J., Ishii, Y., and Kwong, J.M. (2003) Retinal Ganglion Cell Protection with Geranylgeranylacetone, a Heat Shock Protein Inducer, in a Rat Glaucoma Model, Trans. Am. Ophthalmol. Soc. 101, 39-50.
-
(2003)
Trans. Am. Ophthalmol. Soc.
, vol.101
, pp. 39-50
-
-
Caprioli, J.1
Ishii, Y.2
Kwong, J.M.3
-
185
-
-
0034903787
-
Geranylgeranylacetone, a heat shock protein inducer, prevents primary graft nonfunction in rat liver transplantation
-
Fudaba, Y., Ohdan, H., Tashiro, H., Ito, H., Fukuda, Y., Dohi, K., and Asahara, T. (2001) Geranylgeranylacetone, a Heat Shock Protein Inducer, Prevents Primary Graft Nonfunction in Rat Liver Transplantation, Transplantation 72, 184-189.
-
(2001)
Transplantation
, vol.72
, pp. 184-189
-
-
Fudaba, Y.1
Ohdan, H.2
Tashiro, H.3
Ito, H.4
Fukuda, Y.5
Dohi, K.6
Asahara, T.7
-
186
-
-
0038123078
-
Role of protein kinase C in geranylgeranylacetone-induced expression of heat-shock protein 72 and cardioprotection in the rat heart
-
Yamanaka, K., Takahashi, N., Ooie, T., Kaneda, K., Yoshimatsu, H., and Saikawa, T. (2003) Role of Protein Kinase C in Geranylgeranylacetone-Induced Expression of Heat-Shock Protein 72 and Cardioprotection in the Rat Heart, J. Mol. Cell. Cardiol. 35, 785-794.
-
(2003)
J. Mol. Cell. Cardiol.
, vol.35
, pp. 785-794
-
-
Yamanaka, K.1
Takahashi, N.2
Ooie, T.3
Kaneda, K.4
Yoshimatsu, H.5
Saikawa, T.6
-
187
-
-
0031873739
-
Interactions of plaunotol with bacterial membranes
-
Koga, T., Watanabe, H., Kawada, H., Takahashi, K., Utsui, Y., Domon, H., Ishii, C., Narita, T., and Yasuda, H. (1998) Interactions of Plaunotol with Bacterial Membranes, J. Antimicrob. Chemother. 42, 133-140.
-
(1998)
J. Antimicrob. Chemother.
, vol.42
, pp. 133-140
-
-
Koga, T.1
Watanabe, H.2
Kawada, H.3
Takahashi, K.4
Utsui, Y.5
Domon, H.6
Ishii, C.7
Narita, T.8
Yasuda, H.9
-
188
-
-
0023106470
-
Stimulation of prostaglandin production by (2E,6Z,10E)-7-Hydroxymethyl-3, 11,15-trimethyl-2,6,10,14-hexadecatetraen-1-ol (plaunotol), a new anti-ulcer drug, in vitro and in vivo
-
Ushiyama, S., Matsuda, K., Asai, F., and Yamazaki, M. (1987) Stimulation of Prostaglandin Production by (2E,6Z,10E)-7-Hydroxymethyl-3,11,15-trimethyl-2, 6,10,14-hexadecatetraen-1-ol (plaunotol), a New Anti-Ulcer Drug, in vitro and in vivo, Biochem. Pharmacol. 36, 369-375.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 369-375
-
-
Ushiyama, S.1
Matsuda, K.2
Asai, F.3
Yamazaki, M.4
-
189
-
-
0024843759
-
Plaunotol stimulates endogenous secretin release and exocrine pancreatic secretion in rats
-
Chang, J.H., Watanabe, S., Shiratori, K., Moriyoshi, Y., and Takeuchi, T. (1989) Plaunotol Stimulates Endogenous Secretin Release and Exocrine Pancreatic Secretion in Rats, Digestion 44, 142-147.
-
(1989)
Digestion
, vol.44
, pp. 142-147
-
-
Chang, J.H.1
Watanabe, S.2
Shiratori, K.3
Moriyoshi, Y.4
Takeuchi, T.5
-
190
-
-
0028894995
-
Effect of plaunotol on superoxide production activity in vivo
-
Okabe, N., Okada, M., Sakai, T., and Kuroiwa, A. (1995) Effect of Plaunotol on Superoxide Production Activity in vivo, Dig. Dis. Sci. 40, 2321-2322.
-
(1995)
Dig. Dis. Sci.
, vol.40
, pp. 2321-2322
-
-
Okabe, N.1
Okada, M.2
Sakai, T.3
Kuroiwa, A.4
-
191
-
-
0032892122
-
Plaunotol prevents indomethacin-induced gastric mucosal injury in rats by inhibiting neutrophil activation
-
Murakami, K., Okajima, K., Harada, N., Isobe, H., Liu, W., Johno, M., and Okabe, H. (1999) Plaunotol Prevents Indomethacin-Induced Gastric Mucosal Injury in Rats by Inhibiting Neutrophil Activation, Aliment. Pharmacol. Ther. 13, 521-530.
-
(1999)
Aliment. Pharmacol. Ther.
, vol.13
, pp. 521-530
-
-
Murakami, K.1
Okajima, K.2
Harada, N.3
Isobe, H.4
Liu, W.5
Johno, M.6
Okabe, H.7
-
193
-
-
0032729450
-
Biodegradation of free phytol by bacterial communities isolated from marine sediments under aerobic and denitrifying conditions
-
Rontani, J.F., Bonin, P.C., and Volkman, J.K. (1999) Biodegradation of Free Phytol by Bacterial Communities Isolated from Marine Sediments Under Aerobic and Denitrifying Conditions, Appl. Environ. Microbiol. 65, 5484-5492.
-
(1999)
Appl. Environ. Microbiol.
, vol.65
, pp. 5484-5492
-
-
Rontani, J.F.1
Bonin, P.C.2
Volkman, J.K.3
-
194
-
-
0016262979
-
Hydrocarbon metabolism by Brevibacterium erythrogenes: Normal and branched alkanes
-
Pirnik, M.P., Atlas, R.M., and Bartha, R. (1974) Hydrocarbon Metabolism by Brevibacterium erythrogenes: Normal and Branched Alkanes, J. Bacteriol. 119, 868-878.
-
(1974)
J. Bacteriol.
, vol.119
, pp. 868-878
-
-
Pirnik, M.P.1
Atlas, R.M.2
Bartha, R.3
-
195
-
-
0019884097
-
Gas chromatographic separation of diastereomeric isoprenoids as molecular markers of oil pollution
-
Berthou, F., and Friovourt, M.P. (1981) Gas Chromatographic Separation of Diastereomeric Isoprenoids as Molecular Markers of Oil Pollution, J. Chromatogr. A. 219, 393-402.
-
(1981)
J. Chromatogr. A
, vol.219
, pp. 393-402
-
-
Berthou, F.1
Friovourt, M.P.2
-
196
-
-
0028840622
-
Microbial degradation of monoterpenes in the absence of molecular oxygen
-
Harder, J., and Probian, C. (1995) Microbial Degradation of Monoterpenes in the Absence of Molecular Oxygen, Appl. Environ. Microbiol. 61, 3804-3808.
-
(1995)
Appl. Environ. Microbiol.
, vol.61
, pp. 3804-3808
-
-
Harder, J.1
Probian, C.2
-
197
-
-
0036041829
-
Aerobic and anaerobic metabolism of squalene by a denitrifying bacterium isolated from marine sediment
-
Rontani, J.F., Mouzdahir, A., Michotey, V., and Bonin, P. (2002) Aerobic and Anaerobic Metabolism of Squalene by a Denitrifying Bacterium Isolated from Marine Sediment, Arch. Microbiol. 178, 279-287.
-
(2002)
Arch. Microbiol.
, vol.178
, pp. 279-287
-
-
Rontani, J.F.1
Mouzdahir, A.2
Michotey, V.3
Bonin, P.4
-
198
-
-
0030905387
-
Anaerobic mineralization of cholesterol by a novel type of denitrifying bacterium
-
Harder, J., and Probian, C. (1997) Anaerobic Mineralization of Cholesterol by a Novel Type of Denitrifying Bacterium, Arch. Microbiol. 167, 269-274.
-
(1997)
Arch. Microbiol.
, vol.167
, pp. 269-274
-
-
Harder, J.1
Probian, C.2
-
199
-
-
0029743786
-
Aerobic biodegradation of selected monoterpenes
-
Misra, G., Pavlostathis, S.G., Perdue, E.M., and Araujo, R. (1996) Aerobic Biodegradation of Selected Monoterpenes, Appl. Microbiol. Biotechnol. 45, 831-838.
-
(1996)
Appl. Microbiol. Biotechnol.
, vol.45
, pp. 831-838
-
-
Misra, G.1
Pavlostathis, S.G.2
Perdue, E.M.3
Araujo, R.4
-
200
-
-
0041851188
-
Alcanivorax which prevails in oil-contaminated seawater exhibits broad substrate specificity for alkane degradation
-
Hara, A., Syutsubo, K., and Harayama, S. (2003) Alcanivorax Which Prevails in Oil-Contaminated Seawater Exhibits Broad Substrate Specificity for Alkane Degradation, Environ. Microbiol. 5, 746-753.
-
(2003)
Environ. Microbiol.
, vol.5
, pp. 746-753
-
-
Hara, A.1
Syutsubo, K.2
Harayama, S.3
-
201
-
-
0034111150
-
Biodegradation of cis-1,4-Polyisoprene rubbers by distinct actinomycetes: Microbial strategies and detailed surface analysis
-
Linos, A., Berekaa, M.M., Reichelt, R., Keller, U., Schmitt, J., Flemming, H.C., Kroppenstedt, R.M., and Steinbuchel, A. (2000) Biodegradation of cis-1,4-Polyisoprene Rubbers by Distinct Actinomycetes: Microbial Strategies and Detailed Surface Analysis, Appl. Environ. Microbiol. 66, 1639-1645.
-
(2000)
Appl. Environ. Microbiol.
, vol.66
, pp. 1639-1645
-
-
Linos, A.1
Berekaa, M.M.2
Reichelt, R.3
Keller, U.4
Schmitt, J.5
Flemming, H.C.6
Kroppenstedt, R.M.7
Steinbuchel, A.8
-
202
-
-
0016913421
-
Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum
-
Brown, A.G., Smale, T.C., King, T.J., Hasenkamp, R., and Thompson, R.H. (1976) Crystal and Molecular Structure of Compactin, a New Antifungal Metabolite from Penicillium brevicompactum, J. Chem. Soc. Perkin 1, 1165-1170.
-
(1976)
J. Chem. Soc. Perkin.
, vol.1
, pp. 1165-1170
-
-
Brown, A.G.1
Smale, T.C.2
King, T.J.3
Hasenkamp, R.4
Thompson, R.H.5
-
203
-
-
0018500225
-
Kinetic analysis of the reaction catalyzed by rat-liver 3-hydroxy-3-methylglutaryl-coenzyme-A reductase using two specific inhibitors
-
Tanzawa, K., and Endo, A. (1979) Kinetic Analysis of the Reaction Catalyzed by Rat-Liver 3-Hydroxy-3-methylglutaryl-Coenzyme-A Reductase Using Two Specific Inhibitors, Eur. J. Biochem. 98, 195-201.
-
(1979)
Eur. J. Biochem.
, vol.98
, pp. 195-201
-
-
Tanzawa, K.1
Endo, A.2
-
204
-
-
0017807973
-
Inhibitory effects on lipid metabolism in cultured cells of ML-236B, a potent inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase
-
Kaneko, I., Hazama-Shimada, Y., and Endo, A. (1978) Inhibitory Effects on Lipid Metabolism in Cultured Cells of ML-236B, a Potent Inhibitor of 3-Hydroxy-3-methylglutaryl-Coenzyme-A Reductase, Eur. J. Biochem. 87, 313-321.
-
(1978)
Eur. J. Biochem.
, vol.87
, pp. 313-321
-
-
Kaneko, I.1
Hazama-Shimada, Y.2
Endo, A.3
-
205
-
-
0018135853
-
Specific inhibition of desmosterol synthesis by ML-236B in mouse LM cells grown in suspension in a lipid-free medium
-
Doi, O., and Endo, A. (1978) Specific Inhibition of Desmosterol Synthesis by ML-236B in Mouse LM Cells Grown in Suspension in a Lipid-Free Medium, Jpn. J. Med. Sci. Biol. 31, 225-233.
-
(1978)
Jpn. J. Med. Sci. Biol.
, vol.31
, pp. 225-233
-
-
Doi, O.1
Endo, A.2
-
206
-
-
0018381954
-
Hypolipidemic effects in dogs of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase
-
Tsujita, Y., Kuroda, M., Tanzawa, K., Kitano, N., and Endo, A. (1979) Hypolipidemic Effects in Dogs of ML-236B, a Competitive Inhibitor of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase, Atherosclerosis 32, 307-313.
-
(1979)
Atherosclerosis
, vol.32
, pp. 307-313
-
-
Tsujita, Y.1
Kuroda, M.2
Tanzawa, K.3
Kitano, N.4
Endo, A.5
-
207
-
-
0018749065
-
Hypolipidemic effects in monkeys of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase
-
Kuroda, M., Tsujita, Y., Tanzawa, K., and Endo, A. (1979) Hypolipidemic Effects in Monkeys of ML-236B, a Competitive Inhibitor of 3-Hydroxy-3- methylglutaryl Coenzyme A Reductase, Lipids 14, 585-589.
-
(1979)
Lipids
, vol.14
, pp. 585-589
-
-
Kuroda, M.1
Tsujita, Y.2
Tanzawa, K.3
Endo, A.4
-
208
-
-
0018901408
-
Therapeutic effects of ML-236B in primary hypercholesterolemia
-
Yamamoto, A., Sudo, H., and Endo, A. (1980) Therapeutic Effects of ML-236B in Primary Hypercholesterolemia, Atherosclerosis 35, 259-266.
-
(1980)
Atherosclerosis
, vol.35
, pp. 259-266
-
-
Yamamoto, A.1
Sudo, H.2
Endo, A.3
-
209
-
-
0018939225
-
Mevinolin: A highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent
-
Alberts, A.W., Chen, J., Kuron, G., Hunt, V., Huff, J., Hoffman, C., Rothrock, J., Lopez, M., Joshua, H., Harris, E. et al. (1980) Mevinolin: A Highly Potent Competitive Inhibitor of Hydroxymethylglutaryl-Coenzyme A Reductase and a Cholesterol-Lowering Agent, Proc. Natl. Acad. Sci. USA 77, 3957-3961.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 3957-3961
-
-
Alberts, A.W.1
Chen, J.2
Kuron, G.3
Hunt, V.4
Huff, J.5
Hoffman, C.6
Rothrock, J.7
Lopez, M.8
Joshua, H.9
Harris, E.10
-
210
-
-
0027332512
-
Pleurotus fungi produce mevinolin, an inhibitor of HMG CoA reductase
-
Gunde-Cimerman, N., Plemenitas, A., and Cimerman, A. (1993) Pleurotus Fungi Produce Mevinolin, an Inhibitor of HMG CoA Reductase, FEMS Microbiol. Lett. 113, 333-337.
-
(1993)
FEMS Microbiol. Lett.
, vol.113
, pp. 333-337
-
-
Gunde-Cimerman, N.1
Plemenitas, A.2
Cimerman, A.3
-
211
-
-
0028801112
-
A hydroxymethylglutaryl-CoA reductase inhibitor synthesized by yeasts
-
Gunde-Cimerman, N., Plemenitas, A., and Cimerman, A. (1995) A Hydroxymethylglutaryl-CoA Reductase Inhibitor Synthesized by Yeasts, FEMS Microbiol. Lett. 132, 39-43.
-
(1995)
FEMS Microbiol. Lett.
, vol.132
, pp. 39-43
-
-
Gunde-Cimerman, N.1
Plemenitas, A.2
Cimerman, A.3
-
212
-
-
0018592266
-
Monacolin K, a new hypocholesterolemic agent produced by a Monascus species
-
Endo, A. (1979) Monacolin K, a New Hypocholesterolemic Agent Produced by a Monascus Species, J. Antibiot. (Tokyo) 32, 852-854.
-
(1979)
J. Antibiot. (Tokyo)
, vol.32
, pp. 852-854
-
-
Endo, A.1
-
213
-
-
0033644892
-
Studies on mevinolin production by some fungi
-
Shindia, A.A. (2000) Studies on Mevinolin Production by Some Fungi, Microbios 102, 53-61.
-
(2000)
Microbios
, vol.102
, pp. 53-61
-
-
Shindia, A.A.1
-
214
-
-
1842765431
-
Intensive statin therapy - A sea change in cardiovascular prevention
-
Topol, E.J. (2004) Intensive Statin Therapy-A Sea Change in Cardiovascular Prevention, New Engl. J. Med. 350, 1562-1564.
-
(2004)
New Engl. J. Med.
, vol.350
, pp. 1562-1564
-
-
Topol, E.J.1
-
215
-
-
0037233011
-
The statins as anticancer agents
-
Chan, K.K., Oza, A.M., and Siu, L.L. (2003) The Statins as Anticancer Agents, Clin. Cancer Res. 9, 10-19.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 10-19
-
-
Chan, K.K.1
Oza, A.M.2
Siu, L.L.3
-
216
-
-
0037235059
-
Blockade of HMG-CoA reductase activity causes changes in microtubule-stabilizing protein Tau via suppression of geranylgeranylpyrophosphate formation: Implications for Alzheimer's disease
-
Meske, V., Albert, F., Richter, D., Schwarze, J., and Ohm, T.G. (2003) Blockade of HMG-CoA Reductase Activity Causes Changes in Microtubule-Stabilizing Protein Tau via Suppression of Geranylgeranylpyrophosphate Formation: Implications for Alzheimer's Disease, Eur. J. Neurosci. 17, 93-102.
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 93-102
-
-
Meske, V.1
Albert, F.2
Richter, D.3
Schwarze, J.4
Ohm, T.G.5
-
217
-
-
0942276470
-
Use of statins and fracture: Results of 4 prospective studies and cumulative meta-analysis of observational studies and controlled trials
-
Bauer, D.C., Mundy, G.R., Jamal, S.A., Black, D.M., Cauley, J.A., Ensrud, K.E., van der Klift, M., and Pols, H.A. (2004) Use of Statins and Fracture: Results of 4 Prospective Studies and Cumulative Meta-analysis of Observational Studies and Controlled Trials, Arch. Intern. Med. 164, 146-152.
-
(2004)
Arch. Intern. Med.
, vol.164
, pp. 146-152
-
-
Bauer, D.C.1
Mundy, G.R.2
Jamal, S.A.3
Black, D.M.4
Cauley, J.A.5
Ensrud, K.E.6
Van Der Klift, M.7
Pols, H.A.8
-
218
-
-
0037711140
-
Early use of statins in acute coronary syndromes
-
Spin, J.M., and Vagelos, R.H. (2003) Early Use of Statins in Acute Coronary Syndromes, Curr. Atheroscler. Rep. 5, 44-51.
-
(2003)
Curr. Atheroscler. Rep.
, vol.5
, pp. 44-51
-
-
Spin, J.M.1
Vagelos, R.H.2
-
219
-
-
0037065914
-
Statins have biphasic effects on angiogenesis
-
Weis, M., Heeschen, C., Glassford, A.J., and Cooke, J.P. (2002) Statins Have Biphasic Effects on Angiogenesis, Circulation 105, 739-745.
-
(2002)
Circulation
, vol.105
, pp. 739-745
-
-
Weis, M.1
Heeschen, C.2
Glassford, A.J.3
Cooke, J.P.4
-
220
-
-
0035902491
-
Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy
-
Patel, R., Nagueh, S.F., Tsybouleva, N., Abdellatif, M., Lutucuta, S., Kopelen, H.A., Quinones, M.A., Zoghbi, W.A., Entman, M.L., Roberts, R., and Marian, A.J. (2001) Simvastatin Induces Regression of Cardiac Hypertrophy and Fibrosis and Improves Cardiac Function in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy, Circulation 104, 317-324.
-
(2001)
Circulation
, vol.104
, pp. 317-324
-
-
Patel, R.1
Nagueh, S.F.2
Tsybouleva, N.3
Abdellatif, M.4
Lutucuta, S.5
Kopelen, H.A.6
Quinones, M.A.7
Zoghbi, W.A.8
Entman, M.L.9
Roberts, R.10
Marian, A.J.11
-
221
-
-
0037213039
-
Anti-inflammatory and immunomodulatory effects of statins
-
Blanco-Colio, L.M., Tunon, J., Martin-Ventura, J.L., and Egido, J. (2003) Anti-inflammatory and Immunomodulatory Effects of Statins, Kidney Int. 63, 12-23.
-
(2003)
Kidney Int.
, vol.63
, pp. 12-23
-
-
Blanco-Colio, L.M.1
Tunon, J.2
Martin-Ventura, J.L.3
Egido, J.4
-
222
-
-
0038366771
-
Endothelium-dependent effects of statins
-
Wolfrum, S., Jensen, K.S., and Liao, J.K. (2003) Endothelium-Dependent Effects of Statins, Arterioscler. Thromb. Vasc. Biol. 23, 729-736.
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 729-736
-
-
Wolfrum, S.1
Jensen, K.S.2
Liao, J.K.3
-
223
-
-
0042833280
-
Effects of HMG-CoA reductase inhibitors on coagulation and fibrinolysis processes
-
Krysiak, R., Okopien, B., and Herman, Z. (2003) Effects of HMG-CoA Reductase Inhibitors on Coagulation and Fibrinolysis Processes, Drugs. 63, 1821-1854.
-
(2003)
Drugs
, vol.63
, pp. 1821-1854
-
-
Krysiak, R.1
Okopien, B.2
Herman, Z.3
-
224
-
-
0033373592
-
Statins as cellular antithrombotics
-
Fenton, J.W., Jr., and Shen, G.X. (1999) Statins as Cellular Antithrombotics, Haemostasis 29, 166-169.
-
(1999)
Haemostasis
, vol.29
, pp. 166-169
-
-
Fenton Jr., J.W.1
Shen, G.X.2
-
225
-
-
0034887171
-
Polyketide biosynthesis: A millennium review
-
Staunton, J., and Weissman, K.J. (2001) Polyketide Biosynthesis: A Millennium Review, Nat. Prod. Rep. 18, 380-416.
-
(2001)
Nat. Prod. Rep.
, vol.18
, pp. 380-416
-
-
Staunton, J.1
Weissman, K.J.2
-
226
-
-
0036321084
-
Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum
-
Abe, Y., Suzuki, T., Ono, C., Iwamoto, K., Hosobuchi, M., and Yoshikawa, H. (2002) Molecular Cloning and Characterization of an ML-236B (compactin) Biosynthetic Gene Cluster in Penicillium citrinum, Mol. Genet. Genomics 267, 636-646.
-
(2002)
Mol. Genet. Genomics
, vol.267
, pp. 636-646
-
-
Abe, Y.1
Suzuki, T.2
Ono, C.3
Iwamoto, K.4
Hosobuchi, M.5
Yoshikawa, H.6
-
227
-
-
0034450187
-
Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases
-
Hutchinson, C.R., Kennedy, J., Park, C., Kendrew, S., Auclair, K., and Vederas, J. (2000) Aspects of the Biosynthesis of Non-aromatic Fungal Polyketides by Iterative Polyketide Synthases, Antonie van Leeuwenhoek 78, 287-295.
-
(2000)
Antonie van Leeuwenhoek
, vol.78
, pp. 287-295
-
-
Hutchinson, C.R.1
Kennedy, J.2
Park, C.3
Kendrew, S.4
Auclair, K.5
Vederas, J.6
-
228
-
-
0035378199
-
Lovastatin biosynthesis by Aspergillus terreus in a chemically defined medium
-
Hajjaj, H., Niederberger, P., and Duboc, P. (2001) Lovastatin Biosynthesis by Aspergillus terreus in a Chemically Defined Medium, Appl. Environ. Microbiol. 67, 2596-2602.
-
(2001)
Appl. Environ. Microbiol.
, vol.67
, pp. 2596-2602
-
-
Hajjaj, H.1
Niederberger, P.2
Duboc, P.3
-
229
-
-
0035756722
-
Some nutritional factors influencing mevinolin production by Aspergillus terreus strain
-
Shindia, A.A. (2001) Some Nutritional Factors Influencing Mevinolin Production by Aspergillus terreus Strain, Folia Microbiol. (Praha) 46, 413-416.
-
(2001)
Folia Microbiol. (Praha)
, vol.46
, pp. 413-416
-
-
Shindia, A.A.1
-
230
-
-
0023713589
-
Growth inhibition of yeast by compactin (ML-236B) analogues
-
Ikeura, R., Murakawa, S., and Endo, A. (1988) Growth Inhibition of Yeast by Compactin (ML-236B) Analogues, J. Antibiot. (Tokyo) 41, 1148-1150.
-
(1988)
J. Antibiot. (Tokyo)
, vol.41
, pp. 1148-1150
-
-
Ikeura, R.1
Murakawa, S.2
Endo, A.3
-
231
-
-
0020017592
-
Mevinolin: A highly specific inhibitor of microsomal 3-hydroxy-3- methylglutaryl-coenzyme A reductase of radish plants
-
Bach, T.J., and Lichtenthaler, H.K. (1982) Mevinolin: A Highly Specific Inhibitor of Microsomal 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase of Radish Plants, Z. Naturforsch. [C] 37, 46-50.
-
(1982)
Z. Naturforsch. [C]
, vol.37
, pp. 46-50
-
-
Bach, T.J.1
Lichtenthaler, H.K.2
-
232
-
-
0031860650
-
Inhibition of plant growth by mevinolin and reversal of this inhibition by isoprenoids
-
Josekutty, P.C. (1998) Inhibition of Plant Growth by Mevinolin and Reversal of This Inhibition by Isoprenoids, S. Afr. J. Bot. 64, 18-24.
-
(1998)
S. Afr. J. Bot.
, vol.64
, pp. 18-24
-
-
Josekutty, P.C.1
-
233
-
-
0033554651
-
Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates
-
van Beek, E., Pieterman, E., Cohen, L., Lowik, C., and Papapoulos, S. (1999) Farnesyl Pyrophosphate Synthase Is the Molecular Target of Nitrogen-Containing Bisphosphonates, Biochem. Biophys. Res. Commun. 264, 108-111.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 108-111
-
-
Van Beek, E.1
Pieterman, E.2
Cohen, L.3
Lowik, C.4
Papapoulos, S.5
-
234
-
-
0033590114
-
Mechanism of aminobisphosphonate action: Characterization of alendronate inhibition of the isoprenoid pathway
-
Keller, R.K., and Fliesler, S.J. (1999) Mechanism of Aminobisphosphonate Action: Characterization of Alendronate Inhibition of the Isoprenoid Pathway, Biochem. Biophys. Res. Commun. 266, 560-563.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.266
, pp. 560-563
-
-
Keller, R.K.1
Fliesler, S.J.2
-
235
-
-
0033958778
-
Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase
-
Bergstrom, J.D., Bostedor, R.G., Masarachia, P.J., Reszka, A.A., and Rodan, G. (2000) Alendronate Is a Specific, Nanomolar Inhibitor of Farnesyl Diphosphate Synthase, Arch. Biochem. Biophys. 373, 231-241.
-
(2000)
Arch. Biochem. Biophys.
, vol.373
, pp. 231-241
-
-
Bergstrom, J.D.1
Bostedor, R.G.2
Masarachia, P.J.3
Reszka, A.A.4
Rodan, G.5
-
236
-
-
0031977199
-
Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
-
Luckman, S.P., Hughes, D.E., Coxon, F.P., Graham, R., Russell, G., and Rogers, M.J. (1998) Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-translational Prenylation of GTP-Binding Proteins, Including Ras, J. Bone Miner. Res. 13, 581-589.
-
(1998)
J. Bone Miner. Res.
, vol.13
, pp. 581-589
-
-
Luckman, S.P.1
Hughes, D.E.2
Coxon, F.P.3
Graham, R.4
Russell, G.5
Rogers, M.J.6
-
237
-
-
0033520927
-
Bisphosphonates act directly on the osteoclast to induce caspase cleavage of Mstl kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosis-promoting kinase
-
Reszka, A.A., Halasy-Nagy, J.M., Masarachia, P.J., and Rodan, G.A. (1999) Bisphosphonates Act Directly on the Osteoclast to Induce Caspase Cleavage of Mstl Kinase During Apoptosis. A Link Between Inhibition of the Mevalonate Pathway and Regulation of an Apoptosis-Promoting Kinase, J. Biol. Chem. 274, 34967-34973.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34967-34973
-
-
Reszka, A.A.1
Halasy-Nagy, J.M.2
Masarachia, P.J.3
Rodan, G.A.4
-
238
-
-
0032996153
-
Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: Biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs
-
Benford, H.L., Frith, J.C., Auriola, S., Monkkonen, J., and Rogers, M.J. (1999) Farnesol and Geranylgeraniol Prevent Activation of Caspases by Aminobisphosphonates: Biochemical Evidence for Two Distinct Pharmacological Classes of Bisphosphonate Drugs, Mol. Pharmacol. 56, 131-140.
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 131-140
-
-
Benford, H.L.1
Frith, J.C.2
Auriola, S.3
Monkkonen, J.4
Rogers, M.J.5
-
239
-
-
13044283050
-
Alendronate mechanism of action: Geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro
-
Fisher, J.E., Rogers, M.J., Halasy, J.M., Luckman, S.P., Hughes, D.E., Masarachia, P.J., Wesolowski, G., Russell, R.G., Rodan, G.A., and Reszka, A.A. (1999) Alendronate Mechanism of Action: Geranylgeraniol, an Intermediate in the Mevalonate Pathway, Prevents Inhibition of Osteoclast Formation, Bone Resorption, and Kinase Activation in vitro, Proc. Natl. Acad. Sci. USA 96, 133-138.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 133-138
-
-
Fisher, J.E.1
Rogers, M.J.2
Halasy, J.M.3
Luckman, S.P.4
Hughes, D.E.5
Masarachia, P.J.6
Wesolowski, G.7
Russell, R.G.8
Rodan, G.A.9
Reszka, A.A.10
-
240
-
-
0345161422
-
The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates
-
van beek, E., Lowik, C., van der Pluijm, G., and Papapoulos, S. (1999) The Role of Geranylgeranylation in Bone Resorption and Its Suppression by Bisphosphonates in Fetal Bone Explants in vitro: A Clue to the Mechanism of Action of Nitrogen-Containing Bisphosphonates, J. Bone Miner. Res. 14, 722-729.
-
(1999)
J. Bone Miner. Res.
, vol.14
, pp. 722-729
-
-
Van Beek, E.1
Lowik, C.2
Van Der Pluijm, G.3
Papapoulos, S.4
-
241
-
-
0036569635
-
Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway
-
Virtanen, S.S., Vaananen, H.K., Harkonen, P.L., and Lakkakorpi, P.T. (2002) Alendronate Inhibits Invasion of PC-3 Prostate Cancer Cells by Affecting the Mevalonate Pathway, Cancer Res. 62, 2708-2714.
-
(2002)
Cancer Res.
, vol.62
, pp. 2708-2714
-
-
Virtanen, S.S.1
Vaananen, H.K.2
Harkonen, P.L.3
Lakkakorpi, P.T.4
-
242
-
-
0037161612
-
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: A potential route to new bone antiresorption and antiparasitic agents
-
Szabo, C.M., Matsumura, Y., Fukura, S., Martin, M.B., Sanders, J.M., Sengupta, S., Cieslak, J.A., Loftus, T.C., Lea, C.R., Lee, H.J., et al. (2002) Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates and Diphosphates: A Potential Route to New Bone Antiresorption and Antiparasitic Agents, J. Med. Chem. 45, 2185-2196.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 2185-2196
-
-
Szabo, C.M.1
Matsumura, Y.2
Fukura, S.3
Martin, M.B.4
Sanders, J.M.5
Sengupta, S.6
Cieslak, J.A.7
Loftus, T.C.8
Lea, C.R.9
Lee, H.J.10
-
243
-
-
0242290361
-
Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene
-
Ohashi, K., Osuga, J., Tozawa, R., Kitamine, T., Yagyu, H., Sekiya, M., Tomita, S., Okazaki, H., Tamura, Y., Yahagi, N., et al. (2003) Early Embryonic Lethality Caused by Targeted Disruption of the 3-Hydroxy-3-methylglutaryl-CoA Reductase Gene, J. Biol. Chem. 278, 42936-42941.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 42936-42941
-
-
Ohashi, K.1
Osuga, J.2
Tozawa, R.3
Kitamine, T.4
Yagyu, H.5
Sekiya, M.6
Tomita, S.7
Okazaki, H.8
Tamura, Y.9
Yahagi, N.10
-
244
-
-
0022347689
-
Mevalonic aciduria: An inborn error of cholesterol biosynthesis?
-
Berger, R., Smit, G.P., Schierbeek, H., Bijsterveld, K., and le Coultre, R. (1985) Mevalonic Aciduria: An Inborn Error of Cholesterol Biosynthesis? Clin. Chim. Acta 152, 219-222.
-
(1985)
Clin. Chim. Acta
, vol.152
, pp. 219-222
-
-
Berger, R.1
Smit, G.P.2
Schierbeek, H.3
Bijsterveld, K.4
Le Coultre, R.5
-
245
-
-
0038724543
-
Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation
-
Houten, S.M., Frenkel, J., and Waterham, H.R. (2003) Isoprenoid Biosynthesis in Hereditary Periodic Fever Syndromes and Inflammation, Cell. Mol. Life Sci. 60, 1118-1134.
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, pp. 1118-1134
-
-
Houten, S.M.1
Frenkel, J.2
Waterham, H.R.3
-
246
-
-
0021287627
-
Hyperimmunoglobulinaemia D and periodic fever: A new syndrome
-
van der Meer, J.W., Vossen, J.M., Radl, J., van Nieuwkoop, J.A., Meyer, C.J., Lobatto, S., and van Furth, R. (1984) Hyperimmunoglobulinaemia D and Periodic Fever: A New Syndrome, Lancet 1, 1087-1090.
-
(1984)
Lancet
, vol.1
, pp. 1087-1090
-
-
Van Der Meer, J.W.1
Vossen, J.M.2
Radl, J.3
Van Nieuwkoop, J.A.4
Meyer, C.J.5
Lobatto, S.6
Van Furth, R.7
-
247
-
-
0032854744
-
Identification and characterization of three novel missense mutations in mevalonate kinase cDNA causing mevalonic aciduria, a disorder of isoprene biosynthesis
-
Houten, S.M., Romeijn, G.J., Koster, J., Gray, R.G., Darbyshire, P., Smit, G.P., de Klerk, J.B., Duran, M., Gibson, K.M., Wanders, R.J., and Waterham, H.R. (1999) Identification and Characterization of Three Novel Missense Mutations in Mevalonate Kinase cDNA Causing Mevalonic Aciduria, a Disorder of Isoprene Biosynthesis, Hum. Mol. Genet. 8, 1523-1528.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1523-1528
-
-
Houten, S.M.1
Romeijn, G.J.2
Koster, J.3
Gray, R.G.4
Darbyshire, P.5
Smit, G.P.6
De Klerk, J.B.7
Duran, M.8
Gibson, K.M.9
Wanders, R.J.10
Waterham, H.R.11
-
248
-
-
0032987982
-
Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome
-
Houten, S.M., Kuis, W., Duran, M., de Koning, T.J., van Royen-Kerkhof, A., Romeijn, G.J., Frenkel, J., Dorland, L., de Barse, M.M., Huijbers, W.A., et al. (1999) Mutations in MVK, Encoding Mevalonate Kinase, Cause Hyperimmunoglobulinaemia D and Periodic Fever Syndrome, Nat. Genet. 22, 175-177.
-
(1999)
Nat. Genet.
, vol.22
, pp. 175-177
-
-
Houten, S.M.1
Kuis, W.2
Duran, M.3
De Koning, T.J.4
Van Royen-Kerkhof, A.5
Romeijn, G.J.6
Frenkel, J.7
Dorland, L.8
De Barse, M.M.9
Huijbers, W.A.10
-
249
-
-
0035063676
-
Organization of the mevalonate kinase (MVK) gene and identification of novel mutations causing mevalonic aciduria and hyperimmunoglobulinaemia D and periodic fever syndrome
-
Houten, S.M., Koster, J., Romeijn, G.J., Frenkel, J., Di Rocco, M., Caruso, U., Landrieu, P., Kelley, R.I., Kuis, W., Poll-The, B.T., et al. (2001) Organization of the Mevalonate Kinase (MVK) Gene and Identification of Novel Mutations Causing Mevalonic Aciduria and Hyperimmunoglobulinaemia D and Periodic Fever Syndrome, Eur. J. Hum. Genet. 9, 253-259.
-
(2001)
Eur. J. Hum. Genet.
, vol.9
, pp. 253-259
-
-
Houten, S.M.1
Koster, J.2
Romeijn, G.J.3
Frenkel, J.4
Di Rocco, M.5
Caruso, U.6
Landrieu, P.7
Kelley, R.I.8
Kuis, W.9
Poll-The, B.T.10
-
250
-
-
0033358597
-
Identification of a mutation cluster in mevalonate kinase deficiency, including a new mutation in a patient of mennonite ancestry
-
Hinson, D.D., Ross, R.M., Krisans, S., Shaw, J.L., Kozich, V., Rolland, M.O., Divry, P., Mancini, J., Hoffmann, G.F., and Gibson, K.M. (1999) Identification of a Mutation Cluster in Mevalonate Kinase Deficiency, Including a New Mutation in a Patient of Mennonite Ancestry, Am. J. Hum. Genet. 65, 327-335.
-
(1999)
Am. J. Hum. Genet.
, vol.65
, pp. 327-335
-
-
Hinson, D.D.1
Ross, R.M.2
Krisans, S.3
Shaw, J.L.4
Kozich, V.5
Rolland, M.O.6
Divry, P.7
Mancini, J.8
Hoffmann, G.F.9
Gibson, K.M.10
-
251
-
-
0030671277
-
Identification of an active site alanine in mevalonate kinase through characterization of a novel mutation in mevalonate kinase deficiency
-
Hinson, D.D., Chambliss, K.L., Hoffmann, G.F., Krisans, S., Keller, R.K., and Gibson, K.M. (1997) Identification of an Active Site Alanine in Mevalonate Kinase Through Characterization of a Novel Mutation in Mevalonate Kinase Deficiency, J. Biol. Chem. 272, 26756-26760.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26756-26760
-
-
Hinson, D.D.1
Chambliss, K.L.2
Hoffmann, G.F.3
Krisans, S.4
Keller, R.K.5
Gibson, K.M.6
-
252
-
-
0034987162
-
Clinical and molecular variability in childhood periodic fever with hyperimmunoglobulinaemia D
-
Frenkel, J., Houten, S.M., Waterham, H.R., Wanders, R.J., Rijkers, G.T., Duran, M., Kuijpers, T.W., van Luijk, W., Poll-The, B.T., and Kuis, W. (2001) Clinical and Molecular Variability in Childhood Periodic Fever with Hyperimmunoglobulinaemia D, Rheumatology 40, 579-584.
-
(2001)
Rheumatology
, vol.40
, pp. 579-584
-
-
Frenkel, J.1
Houten, S.M.2
Waterham, H.R.3
Wanders, R.J.4
Rijkers, G.T.5
Duran, M.6
Kuijpers, T.W.7
Van Luijk, W.8
Poll-The, B.T.9
Kuis, W.10
-
253
-
-
0027529504
-
Clinical and biochemical phenotype in 11 patients with mevalonic aciduria
-
Hoffmann, G.F., Charpentier, C., Mayatepek, E., Mancini, J., Leichsenring, M., Gibson, K.M., Divry, P., Hrebicek, M., Lehnert, W., Sartor, K., et al. (1993) Clinical and Biochemical Phenotype in 11 Patients with Mevalonic Aciduria, Pediatrics 91, 915-921.
-
(1993)
Pediatrics
, vol.91
, pp. 915-921
-
-
Hoffmann, G.F.1
Charpentier, C.2
Mayatepek, E.3
Mancini, J.4
Leichsenring, M.5
Gibson, K.M.6
Divry, P.7
Hrebicek, M.8
Lehnert, W.9
Sartor, K.10
-
254
-
-
1842869873
-
Temperature dependence of mutant mevalonate kinase activity as a pathogenic factor in Hyper-IgD and periodic fever syndrome
-
Houten, S.M., Frenkel, J., Rijkers, G.T., Wanders, R.J., Kuis, W., and Waterham, H.R. (2002) Temperature Dependence of Mutant Mevalonate Kinase Activity as a Pathogenic Factor in Hyper-IgD and Periodic Fever Syndrome, Hum. Mol. Genet. 11, 3115-3124.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 3115-3124
-
-
Houten, S.M.1
Frenkel, J.2
Rijkers, G.T.3
Wanders, R.J.4
Kuis, W.5
Waterham, H.R.6
-
255
-
-
0023825226
-
Mevalonic aciduria: Pathobiochemical effects of mevalonate kinase deficiency on cholesterol metabolism in intact fibroblasts
-
Hoffmann, G., Gibson, K.M., Nyhan, W.L., and Sweetman, L. (1988) Mevalonic Aciduria: Pathobiochemical Effects of Mevalonate Kinase Deficiency on Cholesterol Metabolism in Intact Fibroblasts, J. Inherit. Metab. Dis. 11, 229-232.
-
(1988)
J. Inherit. Metab. Dis.
, vol.11
, pp. 229-232
-
-
Hoffmann, G.1
Gibson, K.M.2
Nyhan, W.L.3
Sweetman, L.4
-
256
-
-
0025220132
-
3-Hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured fibroblasts from patients with mevalonate kinase deficiency: Differential response to lipid supplied by fetal bovine serum in tissue culture medium
-
Gibson, K.M., Hoffmann, G., Schwall, A., Broock, R.L., Aramaki, S., Sweetman, L., Nyhan, W.L., Brandt, I.K., Wappner, R.S., Lehnert, W., and Trefz, F.H. (1990) 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity in Cultured Fibroblasts from Patients with Mevalonate Kinase Deficiency: Differential Response to Lipid Supplied by Fetal Bovine Serum in Tissue Culture Medium, J. Lipid Res. 31, 515-521.
-
(1990)
J. Lipid Res.
, vol.31
, pp. 515-521
-
-
Gibson, K.M.1
Hoffmann, G.2
Schwall, A.3
Broock, R.L.4
Aramaki, S.5
Sweetman, L.6
Nyhan, W.L.7
Brandt, I.K.8
Wappner, R.S.9
Lehnert, W.10
Trefz, F.H.11
-
257
-
-
0027293794
-
Decreased plasma ubiquinone-10 concentration in patients with mevalonate kinase deficiency
-
Hubner, C., Hoffmann, G.F., Charpentier, C., Gibson, K.M., Finckh, B., Puhl, H., Lehr, H.A., and Kohlschutter, A. (1993) Decreased Plasma Ubiquinone-10 Concentration in Patients with Mevalonate Kinase Deficiency, Pediatr. Res. 34, 129-133.
-
(1993)
Pediatr. Res.
, vol.34
, pp. 129-133
-
-
Hubner, C.1
Hoffmann, G.F.2
Charpentier, C.3
Gibson, K.M.4
Finckh, B.5
Puhl, H.6
Lehr, H.A.7
Kohlschutter, A.8
-
258
-
-
0030888606
-
Regulatory adaptation of isoprenoid biosynthesis and the LDL receptor pathway in fibroblasts from patients with mevalonate kinase deficiency
-
Hoffmann, G.F., Wiesmann, U.N., Brendel, S., Keller, R.K., and Gibson, K.M. (1997) Regulatory Adaptation of Isoprenoid Biosynthesis and the LDL Receptor Pathway in Fibroblasts from Patients with Mevalonate Kinase Deficiency, Pediatr. Res. 41, 541-546.
-
(1997)
Pediatr. Res.
, vol.41
, pp. 541-546
-
-
Hoffmann, G.F.1
Wiesmann, U.N.2
Brendel, S.3
Keller, R.K.4
Gibson, K.M.5
-
259
-
-
0037458669
-
Regulation of isoprenoid/cholesterol biosynthesis in cells from mevalonate kinase-deficient patients
-
Houten, S.M., Schneiders, M.S., Wanders, R.J., and Waterham, H.R. (2003) Regulation of Isoprenoid/Cholesterol Biosynthesis in Cells from Mevalonate Kinase-Deficient Patients, J. Biol. Chem. 278, 5736-5743.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5736-5743
-
-
Houten, S.M.1
Schneiders, M.S.2
Wanders, R.J.3
Waterham, H.R.4
|