Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy

Circulation

Volumn 104, Issue 3, 2001, Pages 317-324

  Patel, Rajnikant ^a   Nagueh, Sherif F ^a   Tsybouleva, Natalie ^a   Abdellatif, Maha ^a   Lutucuta, Silvia ^a   Kopelen, Helen A ^a   Quinones, Miguel A ^a   Zoghbi, William A ^a   Entman, Mark L ^a   Roberts, Robert ^a   Marian, A J ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Section of Cardiology   (United States)

Author keywords

Fibrosis; Genetics; Heart failure; Hypertrophy; Simvastatin

Indexed keywords

COLLAGEN; MYOSIN HEAVY CHAIN; PLACEBO; SIMVASTATIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DIAGNOSTIC IMAGING; DOPPLER ECHOCARDIOGRAPHY; FIBROSIS; GENETIC DISORDER; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE FILLING PRESSURE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; HYPOTHESIS; LUNG FUNCTION; PRIORITY JOURNAL; RABBIT; REGRESSION ANALYSIS; SIGNAL TRANSDUCTION; TWO DIMENSIONAL ECHOCARDIOGRAPHY;

EID: 0035902491     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc2801.094031     Document Type: Article

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