Isoprenoid pyrophosphate analogues regulate expression of ras-related proteins

Biochemistry

Volumn 42, Issue 15, 2003, Pages 4384-4391

  Holstein, Sarah A ^a   Wohlford Lenane, Christine L ^a   Wiemer, David F ^b   Hohl, Raymond J ^a  

^a UNIVERSITY OF IOWA   (United States)

^b E11 SSH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACIDS; ENZYME INHIBITION; MOLECULES; RNA;

CELLULAR FUNCTIONS;

PROTEINS;

ALITRETINOIN; DIHYDROFARNESOL; DIHYDROFARNESYL ACETATE; FARNESOIC ACID; FARNESOIC ACID METHYL ESTER; FARNESOL; FARNESYL ACETATE; FARNESYL TRANS TRANSFERASE; GERANYLGERANIOL; GERANYLGERANYLTRANSFERASE I; GERANYLTRANSFERASE; ISOPRENOID; MESSENGER RNA; MEVALONIC ACID; MEVINOLIN; PHOSPHONIC ACID DERIVATIVE; PROTEIN; PROTEIN FARNESYLTRANSFERASE; PYROPHOSPHORIC ACID DERIVATIVE; RAS RELATED PROTEIN; RETINOIC ACID; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; STRUCTURE ACTIVITY RELATION; SURFACE CHARGE; UPREGULATION;

DIPHOSPHATES; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; MEVALONIC ACID; POLYISOPRENYL PHOSPHATES; RAS PROTEINS; UP-REGULATION;

EID: 0344059127     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi027227m     Document Type: Article

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