Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

Archives of Biochemistry and Biophysics

Volumn 373, Issue 1, 2000, Pages 231-241

  Bergstrom, James D ^a   Bostedor, Richard G ^a   Masarachia, Patricia J ^a   Reszka, Alfred A ^a   Rodan, Gideon ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CLODRONIC ACID; ETIDRONIC ACID; FARNESYL TRANS TRANSFERASE; GERANYLTRANSFERASE; ISOPENTENYL DIPHOSPHATE DELTA ISOMERASE; ISOPRENOID; MEVALONOLACTONE; PAMIDRONIC ACID; RECOMBINANT ENZYME; RISEDRONIC ACID; STEROL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SPECIFICITY; ENZYME INHIBITION; LIVER CYTOSOL; MALE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOPOROSIS; PRENYLATION; PRIORITY JOURNAL; RAT; REACTION ANALYSIS; STEROL SYNTHESIS;

ANIMALIA;

EID: 0033958778     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1999.1502     Document Type: Article

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