p110δ, A novel phosphoinositide 3-kinase in leukocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 9, 1997, Pages 4330-4335

  Vanhaesebroeck, Bart ^a   Welham, Melanie J ^b   Kotani, Kei ^a   Stein, Rob ^a   Warne, Patricia H ^c   Zvelebil, Markéta J ^a   Higashi, Kyoichiro ^a   Volinia, Stefano ^d   Downward, Julian ^c   Waterfield, Michael D ^e  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b University of Bath   (United Kingdom)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d UNIVERSITY OF FERRARA   (Italy)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANDROSTANE DERIVATIVE; CHROMONE DERIVATIVE; COMPLEMENTARY DNA; CYTOKINE RECEPTOR; MORPHOLINE DERIVATIVE; PHOSPHOTRANSFERASE; PROTEIN KINASE; RAS PROTEIN; RECOMBINANT PROTEIN; WORTMANNIN;

ARTICLE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; CLASSIFICATION; COMPARATIVE STUDY; DNA SEQUENCE; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MONOCYTE; MOUSE; PHOSPHORYLATION; PROTEIN BINDING; SEQUENCE HOMOLOGY; SRC HOMOLOGY DOMAIN;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; ANDROSTADIENES; ANIMALS; CHROMONES; CLONING, MOLECULAR; DNA, COMPLEMENTARY; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MONOCYTES; MORPHOLINES; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BINDING; PROTEIN KINASES; RAS PROTEINS; RECEPTORS, CYTOKINE; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SRC HOMOLOGY DOMAINS;

EID: 0030611198     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.9.4330     Document Type: Article

References (50)

1. Zvelebil, M. J., MacDougall, L., Leevers, S., Volinia, S., Vanhaesebroeck, B., Gout, I., Panayotou, G., Domin, J., Stein, R., Koga, H., Salim, K., Linacre, J., Das, P., Panaretou, C., Wetzker, R. & Waterfield, M. D. (1996) Philos. Trans. R. Soc. London 351, 217-233.
2. Stephens, L. R., Jackson, T. R. & Hawkins, P. T. (1993) Biochim. Biophys. Acta 1179, 27-75.
3. Fry, M. (1994) Biochim. Biophys. Acta 1226 237-268.
4. Kapeller, R. & Cantley, L. C. (1994) BioEssays 8, 565-576.
5. Vanhaesebroeck, B., Stein, R. & Waterfield, M. D. (1996) Cancer Surv. 27, 249-270.
6. De Camilli, P., Emr, S. D., McPherson, P. S. & Novick, P. (1996) Science 271, 1533-1539.
7. Hiles, I. D., Otsu, M., Volinia, S., Fry, M. J., Gout, I., Dhand, R., Panayotou, G., Ruiz-Larrea, F., Thompson, A., Totty, N. F., Hsuan, J. J., Courtneidge, S. A., Parker, P. J. & Waterfield, M. (1992) Cell 70, 419-429.
8. Hu, P., Mondino, A., Skolnik, E. Y. & Schlessinger, J. (1993) Mol. Cell. Biol. 13, 7677-7688.
9. Stephens, L., Smrcka, A., Cooke, F. T., Jackson, T. R., Sternweiss, P. C. & Hawkins, P. T. (1994) Cell 77, 83-93.
10. Stoyanov, B., Volinia, S., Hanck, T., Rubio, I., Loubtchenkov, M., Malek, D., Stoyanova, S., Vanhaesebroeck, B., Dhand, R., Nurnberg, B., Gierschik, P., Seedorf, K., Hsuan, J. J., Waterfield, M. D. & Wetzker, R. (1995) Science 269, 690-693.
11. Rodriguez-Viciana, P., Warne, P. H., Dhand, R., Vanhaesebroeck, B., Gout, I., Fry, M. J., Waterfield, M. D. & Downward, J. (1994) Nature (London) 370, 527-532.
12. Rodriguez-Viciana, P., Warne, P. H., Vanhaesebroeck, B., Waterfield, M. D. & Downward, J. (1996) EMBO J. 15, 2442-2451.
13. Stephens, L., Hawkins, P. T., Eguinoa, A. & Cooke, F. (1996) Philos. Trans. R. Soc. London 351, 211-215.
14. MacDougall, L. K., Domin, J. & Waterfield, M. D. (1996) Curr. Biol. 5, 1404-1415.
15. Virbasius, J. V., Guilherme, A. & Czech, M. P. (1996) J. Biol. Chem. 271, 13304-13307.
16. Molz, L., Chen, Y.-W., Hirano, M. & Williams, L. T. (1996) J. Biol. Chem. 271, 13892-13899.
17. Stack, J. H., Horazdovsky, B. & Emr, S. D. (1995) Annu. Rev. Cell. Dev. Biol. 11, 1-33.
18. Toker, A., Meyer, M., Reddy, K. K., Falck, J. R., Aneja, R., Aneja, S., Parra, A., Burns, D. J., Ballas, L. M. & Cantley, L. C. (1994) J. Biol. Chem. 269, 32358-32367.
19. Palmer, R. H., Dekker, L. V., Woscholski, R., Le Good, A., Gigg, R. & Parker, P. J. (1995) J. Biol. Chem. 270, 22412-22416.
20. Burgering, B. M. T. & Coffer, P. J. (1995) Nature (London) 376, 599-602.
21. Franke, T. F., Yang, S. I., Chan, T. O., Datta, K., Kazlauskas, A., Morrison, D. K., Kaplan, D. R. & Tsichlis, P. N. (1995) Cell 81, 727-736.
22. Klippel, A., Reinhard, C., Kavanaugh, W. M., Apell, G., Escobedo, M.-A. & Williams, L. T. (1996) Mol. Cell. Biol. 16, 4117-4127.
23. Chung, J. K., Grammer, T. C., Lemon, K. P., Kazlauskas, A. & Blenis, J. (1994) Nature (London) 370, 71-75.
24. Cross, D. A. E., Alessi, D. R., Cohen, P., Andjelkovich, M. & Hemmings, B. A. (1995) Nature (London) 378, 785-789.
25. Hawkins, P. T., Eguinoa, A., Giu, R.-G., Stokoe, D., Cooke, F. T., Walters, R., Wennström, S., Claesson-Welsh, L., Evans, T., Symons, M. & Stephens, L. (1995) Curr. Biol. 5, 393-403.
26. Li, G., D'Souza-Schorey, C., Barbieri, M. A., Roberts, R. L., Kuppel, A., Williams, L. T. & Stahl, P. D. (1995) Proc. Natl. Acad. Sci. USA 92, 10207-12211.
27. Volinia, S., Dhand, R., Vanhaesebroeck, B., MacDougall, L. K., Stein, R., Zvelebil, M. J., Domin, J., Panaretou, C. & Waterfield, M. D. (1995) EMBO J. 14, 3339-3348.
28. Kozak, M. (1991) J. Biol. Chem. 266, 19867-19870.
29. Dhand, R., Hiles, I., Panayotou, G., Roche, S., Fry, M. J., Totty, N. F., Truong, O., Vicendo, P., Yonezawa, K., Kasuga, M. M., Courtneidge, S. & Waterfield, M. D. (1994) EMBO J. 13, 522-533.
30. Jelinek, T. & Weber, M. J. (1993) BioTechniques 15, 628-630.
31. End, P., Gout, I., Fry, M. J., Panayotou, G., Dhand, R., Yonezawa, K., Kasuga, M. & Waterfield, M. D. (1993) J. Biol. Chem. 268, 10066-10075.
32. Reif, K., Gout, I., Waterfield, M. D. & Cantrell, D. A. (1993) J. Biol. Chem. 268, 10780-10788.
33. Wientjes, F. B., Hsuan, J. J., Totty, N. F. & Segal, A. W. (1993) Biochem. J. 296, 557-561.
34. Welham, M. J. & Schrader, J. W. (1992) J. Immunol. 149, 2772-2783.
35. Palacios, R. & Steinmetz, M. (1985) Cell 41, 727-734.
36. Nabel, G., Galli, S. J., Dvorak, A. M., Dvorak, H. F. & Cantor, H. (1981) Nature (London) 291, 332-334.
37. Welham, M. J., Duronio, V. & Schrader, J. W. (1994) J. Biol. Chem. 269, 5865-5873.
38. Volinia, S., Hiles, I., Ormondroyd, E., Nizetic, D., Antonacci, R., Rocchi, M. & Waterfield, M. (1994) Genomics 24, 472-477.
39. Devereux, J., Haeberli, P. & Smithies, O. (1984) Nucleic Acids Res. 12, 387-395.
40. Leevers, S. J., Weinkove, D., MacDougall, L. K., Hafen, E. & Waterfield, M. D. (1996) EMBO. J. 15, 6584-6594.
41. Pons, S., Asano, T., Glasheen, E., Miralpeix, M., Zhang, Y., Fisher, T. C., Meyers, M. G, Jr., Sun, X. J. & White, M. W. (1995) Mol. Cell. Biol. 15, 4453-4465.
42. Carpenter, C. C., Auger, K. R., Duckworth, B. C., Hou, W.-M., Schaffhausen, B. & Cantley, L. C. (1993) Mol. Cell. Biol. 13 1657-1665.
43. Hartley, D., Meisner, H. & Corvera, S. (1995) J. Biol. Chem. 270, 18260-18263.
44. Lam, K., Carpenter, C. L., Ruderman, N. B., Friel, J. C. & Kelly, K. L. (1994) J. Biol. Chem. 269, 24648-20652.
45. Tanti, J.-F., Grémaux, T., Van Obberghen, E. & Le Marchand-Brustel, Y. (1994) Biochem. J. 304, 17-21.
46. Hunter, T. (1995) Cell 83, 1-4.
47. Ing, Y. L., Leung, I. W., Heng, H. H., Tsui, L.-C. & Lassam, N. J. (1994) Oncogene 9, 1745-1750.
48. Hirai, S., Izawa, M., Osada, S., Spyrou, G. & Ohno, S. (1996) Oncogene 12, 641-650.
49. Springer, T. A. (1994) Cell 76, 301-314.
50. Zhang, J., Zhang, J., Shattil, S. J., Cunningham, M. C. & Kittenhouse, S. E. (1996) J. Biol. Chem. 271, 6265-6272.