The oncogenic properties of mutant p110α and p110β phosphatidylinositol 3-kinases in human mammary epithelial cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 51, 2005, Pages 18443-18448

  Zhao, Jean J ^a,b   Liu, Zhenning ^a,b   Wang, Li ^a   Shin, Eyoung ^a   Loda, Massimo F ^a   Roberts, Thomas M ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Akt; Oncogene; Orthotopical tumor; PIK3CA; PIK3CB

Indexed keywords

AGAR; ARGININE; GLUTAMIC ACID; HISTIDINE; LYSINE; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P110; PROTEIN P110ALPHA; PROTEIN P110BETA; PROTEIN P85; UNCLASSIFIED DRUG;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BREAST EPITHELIUM; CARCINOGENESIS; CONTROLLED STUDY; DELETION MUTANT; ENZYME ACTIVATION; ENZYME SUBUNIT; GENE EXPRESSION; GENE FUSION; GENE MUTATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; ONCOGENE; ONCOGENE SRC; PIK3CA GENE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALLELES; ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BINDING SITES; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; HUMANS; MAMMARY GLANDS, HUMAN; MICE; MICE, NUDE; MOLECULAR WEIGHT; MUTATION; MYRISTIC ACID; NEOPLASM TRANSPLANTATION; NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; MUS MUSCULUS;

EID: 29444449785     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0508988102     Document Type: Article

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