Essential role for the p110δ isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia

Blood

Volumn 106, Issue 3, 2005, Pages 1063-1066

  Sujobert, Pierre ^b   Bardet, Valerie ^b   Cornillet Lefebvre, Pascale ^b   Hayflick, Joel S ^b   Prie, Nolwen ^b   Verdier, Frederic ^b   Vanhaesebroeck, Bart ^b   Muller, Odile ^b   Pesce, Florence ^b   Ifrah, Norbert ^b   Hunault Berger, Mathilde ^b   Berthou, Christian ^b   Villemagne, Bruno ^b   Jourdan, Eric ^b   Audhuy, Bruno ^b   Solary, Eric ^b   Witz, Brigitte ^b   Harousseau, Jean Luc ^b   Himberlin, Chantal ^b   Lamy, Thierry ^b   Lioure, Bruno ^b   Cahn, Jean Yves ^b   Dreyfus, Francois ^b   Mayeux, Patrick ^b   Lacombe, Catherine ^b   Bouscary, Didier ^a   more..

^a AP HP ^*  (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; FLT3 LIGAND; IC 87114; ISOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN INHIBITOR; PROTEIN KINASE B; PROTEIN P100DELTA; PROTEIN P110; PROTEIN P110ALPHA; PROTEIN P110BETA; PROTEIN P110GAMMA; UNCLASSIFIED DRUG; 1 PHOSPHATIDYLINOSITOL 3 KINASE P110 SUBUNIT, HUMAN; 1-PHOSPHATIDYLINOSITOL 3-KINASE P110 SUBUNIT, HUMAN; AKT1 PROTEIN, HUMAN; ISOENZYME; ONCOPROTEIN; PIK3CD PROTEIN, HUMAN; PIK3CD PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BLAST CELL; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MAMMAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ACUTE DISEASE; ADULT; AGED; CELL CULTURE; ENZYMOLOGY; FEMALE; MALE; METABOLISM; MIDDLE AGED; MYELOID LEUKEMIA; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACUTE DISEASE; ADULT; AGED; CELL PROLIFERATION; ENZYME ACTIVATION; FEMALE; HUMANS; ISOENZYMES; LEUKEMIA, MYELOID; MALE; MIDDLE AGED; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TUMOR CELLS, CULTURED;

EID: 22544444889     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-08-3225     Document Type: Article

References (19)

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