Direct effects of caffeine and theophylline on p110δ and other phosphoinositide 3-kinases: Differential effects on lipid kinase and protein kinase activities

Journal of Biological Chemistry

Volumn 277, Issue 40, 2002, Pages 37124-37130

  Foukas, Lazaros C ^a   Daniele, Nathalie ^a   Ktori, Chariklia ^a   Anderson, Karen E ^b   Jensen, Jørgen ^a   Shepherd, Peter R ^b,c  

^a NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; ENZYME INHIBITION; GLUCOSE; INSULIN; LIPIDS; MUSCLE; PHYSIOLOGY;

CAFFIENE;

ENZYMES;

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; 9 CHLORO 2 (2 FURYL) 5,6 DIHYDRO 5 IMINO 1,2,4 TRIAZOLO[2,3 C]QUINAZOLINE; ALLOXAZINE; CAFFEINE; DNA DEPENDENT PROTEIN KINASE; ENPROFYLLINE; ISOBUTYLMETHYLXANTHINE; PD 16948; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; THEOPHYLLINE; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; RAT;

1-METHYL-3-ISOBUTYLXANTHINE; 1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BIOLOGICAL TRANSPORT; CAFFEINE; CHO CELLS; CRICETINAE; DEOXYGLUCOSE; DIMERIZATION; FLAVINS; GLUCOSE; KINETICS; MONOSACCHARIDE TRANSPORT PROTEINS; PHOSPHORYLATION; QUINAZOLINES; RECOMBINANT FUSION PROTEINS; THEOPHYLLINE; TRANSFECTION; TRIAZOLES;

ANIMALIA;

EID: 0037020224     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M202101200     Document Type: Article

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