-
1
-
-
0346455774
-
Activated K-ras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
-
Aguirre, A.J., Bardeesy, N., Sinha, M., Lopez, L., Tuveson, D.A., Horner, J., Redston, M.S. and DePinho, R.A., Activated K-ras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma. Genes Dev. 2003, 17: 3112-3126.
-
(2003)
Genes Dev.
, vol.17
, pp. 3112-3126
-
-
Aguirre, A.J.1
Bardeesy, N.2
Sinha, M.3
Lopez, L.4
Tuveson, D.A.5
Horner, J.6
Redston, M.S.7
DePinho, R.A.8
-
2
-
-
0042835658
-
Surgical resection following radiation therapy with concurrent gemcitabine in patients with previously unresectable adenocarcinoma of the pancreas
-
Ammori, J.B., Colletti, L.M., Zalupski, M.M., Eckhauser, F.E., Greenson J.K., Dimick, J., Lawrence, T.S. and McGinn, C.J., Surgical resection following radiation therapy with concurrent gemcitabine in patients with previously unresectable adenocarcinoma of the pancreas. J. Gastrointest. Surg. 2003, 7: 766-772.
-
(2003)
J. Gastrointest. Surg.
, vol.7
, pp. 766-772
-
-
Ammori, J.B.1
Colletti, L.M.2
Zalupski, M.M.3
Eckhauser, F.E.4
Greenson, J.K.5
Dimick, J.6
Lawrence, T.S.7
McGinn, C.J.8
-
3
-
-
0030757856
-
Gene therapy for peritoneal dissemination of pancreatic cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene
-
Aoki, K., Yoshida, T., Matsumoto, N., Ide, H., Hosokawa, K., Sugimura, T. and Terada, M., Gene therapy for peritoneal dissemination of pancreatic cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene. Hum. Gene Ther. 1997, 8: 1105-1113.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 1105-1113
-
-
Aoki, K.1
Yoshida, T.2
Matsumoto, N.3
Ide, H.4
Hosokawa, K.5
Sugimura, T.6
Terada, M.7
-
4
-
-
0030710098
-
Suppresion of ki-ras p21 levels leading to growth inhibition of pancreatic cancer cell lines with ki-ras mutation but not those without ki-ras mutation
-
Aoki, K., Yoshida, T., Matsumoto, N., Ide, H., Sugimura, T. and Terada, M., Suppresion of ki-ras p21 levels leading to growth inhibition of pancreatic cancer cell lines with ki-ras mutation but not those without ki-ras mutation. Mol. Carcinogen 1997, 20: 251-258.
-
(1997)
Mol. Carcinogen
, vol.20
, pp. 251-258
-
-
Aoki, K.1
Yoshida, T.2
Matsumoto, N.3
Ide, H.4
Sugimura, T.5
Terada, M.6
-
5
-
-
0037010076
-
Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia
-
Arteaga, C.L., Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia. Sem. Oncol. 2002, 29: 3-9.
-
(2002)
Sem. Oncol.
, vol.29
, pp. 3-9
-
-
Arteaga, C.L.1
-
6
-
-
0036883940
-
Pancreatic cancer biology and genetics
-
Bardeesy, N. and DePinho, R.A., Pancreatic cancer biology and genetics. Nat. Rev. Cancer 2002, 2: 897-909.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 897-909
-
-
Bardeesy, N.1
DePinho, R.A.2
-
7
-
-
0028953137
-
Antisense oligonucleotides directed against p53 have antiproliferative effects unrelated to effects on p53 expression
-
Barton, C.M. and Lemoine, N.R., Antisense oligonucleotides directed against p53 have antiproliferative effects unrelated to effects on p53 expression. Br. J. Cancer 1995, 71: 429-437.
-
(1995)
Br. J. Cancer
, vol.71
, pp. 429-437
-
-
Barton, C.M.1
Lemoine, N.R.2
-
8
-
-
0001388461
-
Adenoviral gene therapy for cancer: From vectors to targeted and replication competent agents
-
Bauerschmitz, G.J., Barker, S.D. and Hemminki, A., Adenoviral gene therapy for cancer: from vectors to targeted and replication competent agents. Int. J. Oncol 2002, 21: 1161-1174 (review).
-
(2002)
Int. J. Oncol
, vol.21
, pp. 1161-1174
-
-
Bauerschmitz, G.J.1
Barker, S.D.2
Hemminki, A.3
-
9
-
-
0042303768
-
Overview of therapeutic vaccination approaches for cancer
-
Berinstein, N., Overview of therapeutic vaccination approaches for cancer. Sem. Oncol. 2003, 30: 1-8.
-
(2003)
Sem. Oncol.
, vol.30
, pp. 1-8
-
-
Berinstein, N.1
-
10
-
-
0031666927
-
K-ras mutations in stools and tissue samples from patients with malignant and non-malignant pancreatic diseases
-
Berndt, C., Haubold, K., Wenger, F., Brux, B., Muller, J., Bendzko, P., Hillebrand, T., Kottgen, E. and Zanow, J., K-ras mutations in stools and tissue samples from patients with malignant and non-malignant pancreatic diseases. Clin. Chem. 1998, 44: 2103-2107.
-
(1998)
Clin. Chem.
, vol.44
, pp. 2103-2107
-
-
Berndt, C.1
Haubold, K.2
Wenger, F.3
Brux, B.4
Muller, J.5
Bendzko, P.6
Hillebrand, T.7
Kottgen, E.8
Zanow, J.9
-
11
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff, J.R., Kirn, D.H., Williams, A., Heise, C., Horn, S., Muna, M., Ng, L., Nye, J.A., Sampson-Johannes, A., Fattaey, A. and McCormick, F., An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 1996, 274(5286): 373-376.
-
(1996)
Science
, vol.274
, Issue.5286
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
Heise, C.4
Horn, S.5
Muna, M.6
Ng, L.7
Nye, J.A.8
Sampson-Johannes, A.9
Fattaey, A.10
McCormick, F.11
-
12
-
-
0033837513
-
Antitumoral effect of a non-viral interleukin-2 gene therapy is enhanced by combination with 5-fluorouracil
-
Bishop, J.,S., Thull, N.M., Matar, M., Quezada, A., Munger, W.E., Batten, T.L., Muller, S. and Pericle, F., Antitumoral effect of a non-viral interleukin-2 gene therapy is enhanced by combination with 5-fluorouracil. Cancer Gene Ther. 2000, 7: 1165-1171.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1165-1171
-
-
Bishop, J.S.1
Thull, N.M.2
Matar, M.3
Quezada, A.4
Munger, W.E.5
Batten, T.L.6
Muller, S.7
Pericle, F.8
-
13
-
-
0030686481
-
Adenoviral-mediated herpes simplex virus thymidine kinase gene transfer: Regression of hepatic metastasis of pancreatic tumors
-
Block, A., Chen, S.-H., Kosai, K.-I., Finegold, M. and Woo, S.L.C., Adenoviral-mediated herpes simplex virus thymidine kinase gene transfer: regression of hepatic metastasis of pancreatic tumors. Pancreas 1997, 15: 25-34.
-
(1997)
Pancreas
, vol.15
, pp. 25-34
-
-
Block, A.1
Chen, S.-H.2
Kosai, K.-I.3
Finegold, M.4
Woo, S.L.C.5
-
14
-
-
0031648811
-
Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer
-
Bouvet, M., Bold, R.J., Lee, J., Evans, D.B., Abbruzzese, J.L., Chiao, P.J., McConkey D.J., Chandra, J., Chada, S., Fang, B. and Roth, J.A., Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer. Ann. Surg. Oncol. 1998, 5: 667-669.
-
(1998)
Ann. Surg. Oncol.
, vol.5
, pp. 667-669
-
-
Bouvet, M.1
Bold, R.J.2
Lee, J.3
Evans, D.B.4
Abbruzzese, J.L.5
Chiao, P.J.6
McConkey, D.J.7
Chandra, J.8
Chada, S.9
Fang, B.10
Roth, J.A.11
-
15
-
-
9244237087
-
Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer
-
Buscail, L., Saint-Laurent, N., Chastre, E., Vaillant, J.-C., Gespach, C., Capellà, G., Kalthoff, H., Lluis, F., Vaysse, N. and Susini, C., Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer. Cancer Res. 1996, 56: 1823-1827.
-
(1996)
Cancer Res.
, vol.56
, pp. 1823-1827
-
-
Buscail, L.1
Saint-Laurent, N.2
Chastre, E.3
Vaillant, J.-C.4
Gespach, C.5
Capellà, G.6
Kalthoff, H.7
Lluis, F.8
Vaysse, N.9
Susini, C.10
-
16
-
-
0034774666
-
Adenovirus-mediated wt-p16 reintroduction induces cell cycle arrest or apoptosis in pancreatic cancer
-
Calbò, J., Marotta, M., Cascallo, M., Roig, J.M., Gelpi, J.L., Fueyo, J. and Mazo, A., Adenovirus-mediated wt-p16 reintroduction induces cell cycle arrest or apoptosis in pancreatic cancer. Cancer Gene Ther. 2001, 8: 740-750.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 740-750
-
-
Calbò, J.1
Marotta, M.2
Cascallo, M.3
Roig, J.M.4
Gelpi, J.L.5
Fueyo, J.6
Mazo, A.7
-
17
-
-
0035479932
-
Retrovirus-mediated transfer of the herpes simplex virus thymidine kinase and connexin26 genes in pancreatic cells. Results in variable efficiency on the bystander killing: Implications for gene therapy
-
Carriò, M., Mazo, A., López-Iglesias, C., Estivill, X. and Fillat, C., Retrovirus-mediated transfer of the herpes simplex virus thymidine kinase and connexin26 genes in pancreatic cells. Results in variable efficiency on the bystander killing: implications for gene therapy. Int. J. Cancer 2001, 94: 81-88.
-
(2001)
Int. J. Cancer
, vol.94
, pp. 81-88
-
-
Carriò, M.1
Mazo, A.2
López-Iglesias, C.3
Estivill, X.4
Fillat, C.5
-
18
-
-
0032959726
-
Enhanced pancreatic tumor regression by a combination of adenovirus and retrovirus-mediated delivery of herpes simplex virus thymidine kinase gene
-
Carriò, M., Romagosa, A., Mercadè, E., Mazo, A., Nadal, M., Gomez-Foix, A.-M. and Filial, C., Enhanced pancreatic tumor regression by a combination of adenovirus and retrovirus-mediated delivery of herpes simplex virus thymidine kinase gene. Gene Ther. 1999, 6: 547-553.
-
(1999)
Gene Ther.
, vol.6
, pp. 547-553
-
-
Carriò, M.1
Romagosa, A.2
Mercadè, E.3
Mazo, A.4
Nadal, M.5
Gomez-Foix, A.-M.6
Filial, C.7
-
19
-
-
0033190986
-
Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells
-
Cascallo, M., Mercade, E., Capella, G., Lluis, F., Fillat, C., Gomez-Foix, A.M. and Mazo, A., Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells. Cancer Gene Ther. 1999, 6: 428-436.
-
(1999)
Cancer Gene Ther.
, vol.6
, pp. 428-436
-
-
Cascallo, M.1
Mercade, E.2
Capella, G.3
Lluis, F.4
Fillat, C.5
Gomez-Foix, A.M.6
Mazo, A.7
-
20
-
-
0142218032
-
Somatostatin receptor gene transfer inhibits established pancreatic cancer xenografis
-
Celinski, S.A., Fisher, W.E., Amaya, F., Wu, Y.Q., Yao, Q., Youker, K.A. and Li, M., Somatostatin receptor gene transfer inhibits established pancreatic cancer xenografis. J. Surg. Res. 2003, 115: 41-47.
-
(2003)
J. Surg. Res.
, vol.115
, pp. 41-47
-
-
Celinski, S.A.1
Fisher, W.E.2
Amaya, F.3
Wu, Y.Q.4
Yao, Q.5
Youker, K.A.6
Li, M.7
-
21
-
-
0031849597
-
Targeting tumor cells via EGF receptors: Selective toxicity of an HBEGF-toxin fusion protein
-
Chandler, L.A., Sosnowski, B.A., McDonald, J.R., Price, J.E., Aukerman, S.L., Baird, A., Pierce, G.F. and Houston, L.L., Targeting tumor cells via EGF receptors: selective toxicity of an HBEGF-toxin fusion protein. Int. J. Cancer 1998, 78: 106-111.
-
(1998)
Int. J. Cancer
, vol.78
, pp. 106-111
-
-
Chandler, L.A.1
Sosnowski, B.A.2
McDonald, J.R.3
Price, J.E.4
Aukerman, S.L.5
Baird, A.6
Pierce, G.F.7
Houston, L.L.8
-
22
-
-
0037183984
-
Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells
-
Chen, W.B., Lenschow, W., Tiede, K., Fischer, J.W., Kalthoff, H., and Ungefroren, H. Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells. J. Biol. Chem. 2002, 277: 36118-36128.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36118-36128
-
-
Chen, W.B.1
Lenschow, W.2
Tiede, K.3
Fischer, J.W.4
Kalthoff, H.5
Ungefroren, H.6
-
23
-
-
0015217337
-
Structure and activity of diphteria toxin. I. Thiol dependent dissociation of a fraction of toxin into enzymatically active and inactive fragments
-
Collier, R.J. and Kandel, J., Structure and activity of diphteria toxin. I. Thiol dependent dissociation of a fraction of toxin into enzymatically active and inactive fragments. J. Biol. Chem. 1971, 246: 1496-1503.
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 1496-1503
-
-
Collier, R.J.1
Kandel, J.2
-
24
-
-
0034003075
-
TIEG proteins join the Smads as TGF-β-regulated transcription factors that control pancreatic cell growth
-
Cook, T. and Urrutia, R., TIEG proteins join the Smads as TGF-β-regulated transcription factors that control pancreatic cell growth. Am. J. Physiol. Gastrointest. Liver Physiol. 2000, 278: G513-G521.
-
(2000)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.278
-
-
Cook, T.1
Urrutia, R.2
-
25
-
-
0141724605
-
The genetics of pancreatic cancer
-
Cowgill, S.M. and Muscarella, P., The genetics of pancreatic cancer. Am. J. Surg. 2003, 186: 279-286.
-
(2003)
Am. J. Surg.
, vol.186
, pp. 279-286
-
-
Cowgill, S.M.1
Muscarella, P.2
-
26
-
-
0031025637
-
Sst2 somatostatin receptor expression reverses tumorigenicity of human pancreatic cancer cells
-
Delesque, N., Buscail, L., Esteve, J.-P., Saint-Laurent, N., Muller, C., Weckbecker, G., Bruns, C., Vaysse, N. and Susini, C., Sst2 somatostatin receptor expression reverses tumorigenicity of human pancreatic cancer cells. Cancer Res. 1997, 57: 956-962.
-
(1997)
Cancer Res.
, vol.57
, pp. 956-962
-
-
Delesque, N.1
Buscail, L.2
Esteve, J.-P.3
Saint-Laurent, N.4
Muller, C.5
Weckbecker, G.6
Bruns, C.7
Vaysse, N.8
Susini, C.9
-
27
-
-
0347302952
-
Cytokines in cancer pathogenesis and cancer therapy
-
Dranoff, G., Cytokines in cancer pathogenesis and cancer therapy. Nature Rev. 2004, 4: 11-22.
-
(2004)
Nature Rev.
, vol.4
, pp. 11-22
-
-
Dranoff, G.1
-
28
-
-
0242490137
-
Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells
-
Duda, D.G., Sunamura, M., Lefter, L.P., Furukawa, T., Yokoyama, T., Yatsuoka, T., Abe, T., Inoue, H., Motoi, F., Egawa, S., Matsuno, S. and Horii, A., Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells. Oncogene 2003, 22: 6857-6864.
-
(2003)
Oncogene
, vol.22
, pp. 6857-6864
-
-
Duda, D.G.1
Sunamura, M.2
Lefter, L.P.3
Furukawa, T.4
Yokoyama, T.5
Yatsuoka, T.6
Abe, T.7
Inoue, H.8
Motoi, F.9
Egawa, S.10
Matsuno, S.11
Horii, A.12
-
29
-
-
0037280222
-
Metastatic pancreatic cancer: Emerging strategies in chemotherapy and palliative care
-
El Kamar, F.G., Grossbard, M.L. and Kozuch, P.S., Metastatic pancreatic cancer: emerging strategies in chemotherapy and palliative care. The Oncologist 2003, 8: 18-34.
-
(2003)
The Oncologist
, vol.8
, pp. 18-34
-
-
El Kamar, F.G.1
Grossbard, M.L.2
Kozuch, P.S.3
-
30
-
-
0029913138
-
Gap junction play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro
-
Elshami, A.A., Saavedra, A., Zhang, H., Kucharczuk, J.C., Spray, D.C., Fishman, G.I., Amin, K.M., Kaiser, L.R. and Albelda, S.M., Gap junction play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro. Gene Ther. 1996, 3: 85-92.
-
(1996)
Gene Ther.
, vol.3
, pp. 85-92
-
-
Elshami, A.A.1
Saavedra, A.2
Zhang, H.3
Kucharczuk, J.C.4
Spray, D.C.5
Fishman, G.I.6
Amin, K.M.7
Kaiser, L.R.8
Albelda, S.M.9
-
31
-
-
0034660858
-
In vivo cancer gene therapy by adenovirus-mediated transfer of bifunctional yeast cytosine deaminasi/uracil phosphoribosyltransferase fusion gene
-
Erbs, P., Regulier, E., Kintz, J., Leroy P., Poitevin, Y., Exinger, F., Jund, R. and Mehtali, M., In vivo cancer gene therapy by adenovirus-mediated transfer of bifunctional yeast cytosine deaminasi/uracil phosphoribosyltransferase fusion gene. Cancer Res. 2000, 60: 3813-3822.
-
(2000)
Cancer Res.
, vol.60
, pp. 3813-3822
-
-
Erbs, P.1
Regulier, E.2
Kintz, J.3
Leroy, P.4
Poitevin, Y.5
Exinger, F.6
Jund, R.7
Mehtali, M.8
-
32
-
-
0031127632
-
In vivo adenoviral-mediated gene transfer in the treatment of pancreatic cancer
-
Evoy D., Hirschowitz, E.A., Naama, H.A., Kui, X., Crystal, R.G., Daly J.M. and Lieberman, M.D., In vivo adenoviral-mediated gene transfer in the treatment of pancreatic cancer. J. Surg. Res. 1997, 69: 226-231.
-
(1997)
J. Surg. Res.
, vol.69
, pp. 226-231
-
-
Evoy, D.1
Hirschowitz, E.A.2
Naama, H.A.3
Kui, X.4
Crystal, R.G.5
Daly, J.M.6
Lieberman, M.D.7
-
33
-
-
0025233918
-
Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infection
-
Faulds, D. and Rennie, C.H., Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infection. Drugs 1990, 39: 567-638.
-
(1990)
Drugs
, vol.39
, pp. 567-638
-
-
Faulds, D.1
Rennie, C.H.2
-
34
-
-
0036290018
-
Somatostatin receptor subtype 2 gene therapy inhibits pancreatic cancer in vitro
-
Fisher, W.E., Wu, Y.Q., Amaya, F. and Berger, D.H., Somatostatin receptor subtype 2 gene therapy inhibits pancreatic cancer in vitro. J. Surg. Res. 2002, 105: 58-64.
-
(2002)
J. Surg. Res.
, vol.105
, pp. 58-64
-
-
Fisher, W.E.1
Wu, Y.Q.2
Amaya, F.3
Berger, D.H.4
-
35
-
-
0344464885
-
Suicide gene therapy with HSV-TK in pancreatic cancer has no effect in vivo in a mouse model
-
Fogar, P., Greco, E., Basso, D., Habeler, W., Navaglia, F., Zambon, C.-F., Tormen, D., Gallo, N., Cecchetto, A., Plebani, M. and Pedrazzoli, S., Suicide gene therapy with HSV-TK in pancreatic cancer has no effect in vivo in a mouse model. Eur. J. Surg. Oncol. 2003, 29: 721-730.
-
(2003)
Eur. J. Surg. Oncol.
, vol.29
, pp. 721-730
-
-
Fogar, P.1
Greco, E.2
Basso, D.3
Habeler, W.4
Navaglia, F.5
Zambon, C.-F.6
Tormen, D.7
Gallo, N.8
Cecchetto, A.9
Plebani, M.10
Pedrazzoli, S.11
-
36
-
-
0036840044
-
Malignant progenitors from patients with CD87+ acute myelogenous leucemia are sensitive to a diphtheria toxin-urokinase fusion protein
-
Frankel, A.E., Beran, M., Hogge, D.E., Powell, B.L., Thorburn, A., Chen, Y.Q. and Vallera, D.A., Malignant progenitors from patients with CD87+ acute myelogenous leucemia are sensitive to a diphtheria toxin-urokinase fusion protein. Exp. Hematol. 2002, 30: 1316-1323.
-
(2002)
Exp. Hematol.
, vol.30
, pp. 1316-1323
-
-
Frankel, A.E.1
Beran, M.2
Hogge, D.E.3
Powell, B.L.4
Thorburn, A.5
Chen, Y.Q.6
Vallera, D.A.7
-
37
-
-
0041736005
-
Immunotoxin therapy of hematologic malignancies
-
Frankel, A.E., Neville, D.M., Bugge, T.A., Kreitman, R.J. and Leppla, S.H., Immunotoxin therapy of hematologic malignancies. Sem. Oncol. 2003, 30: 545-557.
-
(2003)
Sem. Oncol.
, vol.30
, pp. 545-557
-
-
Frankel, A.E.1
Neville, D.M.2
Bugge, T.A.3
Kreitman, R.J.4
Leppla, S.H.5
-
38
-
-
0038315196
-
Diphtheria toxin coniugate therapy of cancer
-
Giaccone, G, Schilsky R. and Sondel, P. (eds.), Elsevier Science
-
Frankel, A.E., Powell, B.L. and Lilly, M.B., Diphtheria toxin coniugate therapy of cancer. In: Cancer Chemotherapy and Biological Response Modifiers, Annual 20, Giaccone, G, Schilsky R. and Sondel, P. (eds.), Elsevier Science, 2002, pp. 301-313.
-
(2002)
Cancer Chemotherapy and Biological Response Modifiers, Annual 20
, pp. 301-313
-
-
Frankel, A.E.1
Powell, B.L.2
Lilly, M.B.3
-
39
-
-
0035114253
-
Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo
-
Ghaneh, P., Greenhalf, W., Humphreys, M., Wilson, D., Zumstein, L., Lemoine, N.R. and Neoptolemos, J.P., Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo. Gene Ther. 2001, 8: 199-208.
-
(2001)
Gene Ther.
, vol.8
, pp. 199-208
-
-
Ghaneh, P.1
Greenhalf, W.2
Humphreys, M.3
Wilson, D.4
Zumstein, L.5
Lemoine, N.R.6
Neoptolemos, J.P.7
-
40
-
-
0033168564
-
Enzymatic and antisense effects of a specific anti ki-ras ribozyme in vitro and in cell culture
-
Giannini, C.D., Roth, W.K., Piiper, A. and Zeuzem, S., Enzymatic and antisense effects of a specific anti ki-ras ribozyme in vitro and in cell culture. Nucl. Acids Res. 1999, 13: 2737-2744.
-
(1999)
Nucl. Acids Res.
, vol.13
, pp. 2737-2744
-
-
Giannini, C.D.1
Roth, W.K.2
Piiper, A.3
Zeuzem, S.4
-
41
-
-
0036620226
-
Emerginge biological therapies for pancreatic carcinoma
-
Gilliam, A.D. and Watson, S.A., Emerginge biological therapies for pancreatic carcinoma. Eur. J. Surg. Oncol. 2002, 28: 370-378.
-
(2002)
Eur. J. Surg. Oncol.
, vol.28
, pp. 370-378
-
-
Gilliam, A.D.1
Watson, S.A.2
-
42
-
-
0036676939
-
Retrovirus-mediated herpes simplex virus thymidine kinase gene transfer in pancreatic cancer cell lines: An incomplete antitumor effect
-
Greco, E., Fogar, P., Basso, D., Stefani, A.L., Navaglia, F., Zambon, C.-F., Mazza, S., Gallo, N., Piva, M.G., Scarpa, A., Pedrazzoli, S. and Plebani, M., Retrovirus-mediated herpes simplex virus thymidine kinase gene transfer in pancreatic cancer cell lines: an incomplete antitumor effect. Pancreas 2002, 25: 21-29.
-
(2002)
Pancreas
, vol.25
, pp. 21-29
-
-
Greco, E.1
Fogar, P.2
Basso, D.3
Stefani, A.L.4
Navaglia, F.5
Zambon, C.-F.6
Mazza, S.7
Gallo, N.8
Piva, M.G.9
Scarpa, A.10
Pedrazzoli, S.11
Plebani, M.12
-
43
-
-
0033959520
-
Cancer statistics, 2000
-
Greenlee, R.T., Murray, T., Golden, S. and Wingo, P.A., Cancer statistics, 2000. Cancer J. Clin. 2000, 50: 7-33.
-
(2000)
Cancer J. Clin.
, vol.50
, pp. 7-33
-
-
Greenlee, R.T.1
Murray, T.2
Golden, S.3
Wingo, P.A.4
-
44
-
-
0037422536
-
Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis
-
Guillermet, J., Saint-Laurent, N., Rochaix, P., Cuvillier, O., Levade, T., Schally A.V., Pradayrol, L., Buscail, L., Susini, C. and Bousquet, C., Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis. PNAS 2003, 100: 155-160.
-
(2003)
PNAS
, vol.100
, pp. 155-160
-
-
Guillermet, J.1
Saint-Laurent, N.2
Rochaix, P.3
Cuvillier, O.4
Levade, T.5
Schally, A.V.6
Pradayrol, L.7
Buscail, L.8
Susini, C.9
Bousquet, C.10
-
45
-
-
0346725985
-
Combined suicide gene therapy for pancreatic peritoneal carcinomatosis using BGTC liposomes
-
Hajri, A., Wack, S., Lehn, P., Vigneron, J.-P., Lehn, J.-M., Marescaux, J. and Aprahamian, M., Combined suicide gene therapy for pancreatic peritoneal carcinomatosis using BGTC liposomes. Cancer Gene Ther. 2004, 11: 16-27.
-
(2004)
Cancer Gene Ther.
, vol.11
, pp. 16-27
-
-
Hajri, A.1
Wack, S.2
Lehn, P.3
Vigneron, J.-P.4
Lehn, J.-M.5
Marescaux, J.6
Aprahamian, M.7
-
46
-
-
0041335589
-
New perspectives in the management of pancreas cancer
-
Haller, D.G., New perspectives in the management of pancreas cancer. Sem. Oncol. 2003, 30(11): 3-10.
-
(2003)
Sem. Oncol.
, vol.30
, Issue.11
, pp. 3-10
-
-
Haller, D.G.1
-
47
-
-
0032813559
-
Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs
-
Harvey, B.-G., Hackett, N.R., El-Sawy, T., Rosengart, T.K., Hirschowitz, E.A., Lieberman, M.D., Lesser, M.L. and Crystal, R.G., Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs. J. Virol. 1999, 73: 6729-6742.
-
(1999)
J. Virol.
, vol.73
, pp. 6729-6742
-
-
Harvey, B.-G.1
Hackett, N.R.2
El-Sawy, T.3
Rosengart, T.K.4
Hirschowitz, E.A.5
Lieberman, M.D.6
Lesser, M.L.7
Crystal, R.G.8
-
48
-
-
0037314610
-
A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma
-
Hecht, J.R., Bedford, R., Abbruzzese, J.L., Lahoti; S., Reid, T.R., Soetikno, R.M., Kim, D.H. and Freeman, S.M., A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Clin. Cancer Res. 2003, 9: 555-561.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 555-561
-
-
Hecht, J.R.1
Bedford, R.2
Abbruzzese, J.L.3
Lahoti, S.4
Reid, T.R.5
Soetikno, R.M.6
Kim, D.H.7
Freeman, S.M.8
-
49
-
-
19044367102
-
Specific targeting of tumor vasculature by diphtheria toxin-vascular endothelial growth factor fusion protein reduces angiogenesis and growth of pancreatic cancer
-
Hotz, H.G., Gill, P.S., Masood, R., Hotz, B., Buhr, H.J,, Foitzik, T., Hines, O.J. and Reber, H.A., Specific targeting of tumor vasculature by diphtheria toxin-vascular endothelial growth factor fusion protein reduces angiogenesis and growth of pancreatic cancer. J. Gastrointest. Surg. 2002, 6: 159-166.
-
(2002)
J. Gastrointest. Surg.
, vol.6
, pp. 159-166
-
-
Hotz, H.G.1
Gill, P.S.2
Masood, R.3
Hotz, B.4
Buhr, H.J.5
Foitzik, T.6
Hines, O.J.7
Reber, H.A.8
-
50
-
-
0032813205
-
Enhanced retroviral transduction efficiency of pancreatic tumor cell lines using different envelope glycoproteins
-
Howard, B.D., Boenicke, L., Schneider-Brachert, W. and Kalthoff, H., Enhanced retroviral transduction efficiency of pancreatic tumor cell lines using different envelope glycoproteins. Ann. N.Y. Acad. Sci. USA 1999, 880: 366-370.
-
(1999)
Ann. N.Y. Acad. Sci. USA
, vol.880
, pp. 366-370
-
-
Howard, B.D.1
Boenicke, L.2
Schneider-Brachert, W.3
Kalthoff, H.4
-
51
-
-
0032831940
-
The potential for gene therapy in pancreatic cancer
-
Humphreys, M.J., Greenhalf, W., Neoptolemos, J.P. and Ghaneh, P., The potential for gene therapy in pancreatic cancer. Int. J. Pancreatol. 1999, 26: 5-21.
-
(1999)
Int. J. Pancreatol.
, vol.26
, pp. 5-21
-
-
Humphreys, M.J.1
Greenhalf, W.2
Neoptolemos, J.P.3
Ghaneh, P.4
-
52
-
-
0035328523
-
Cancer immunotherapy using a DNA vaccine encoding the translocation domain of a bacterial toxin linked to a tumor antigen
-
Hung, C.-F., Cheng, W.-F., Hsu, K.-F., Chai, C.-Y., He, L., Ling, M. and Wu, T.-C., Cancer immunotherapy using a DNA vaccine encoding the translocation domain of a bacterial toxin linked to a tumor antigen. Cancer Res. 2001, 61: 3698-3703.
-
(2001)
Cancer Res.
, vol.61
, pp. 3698-3703
-
-
Hung, C.-F.1
Cheng, W.-F.2
Hsu, K.-F.3
Chai, C.-Y.4
He, L.5
Ling, M.6
Wu, T.-C.7
-
53
-
-
0031830091
-
Gene therapy for primary and metastatic pancreatic cancer with intraperitoneal retroviral vector bearing the wild-type p53 gene
-
Hwang, R.F., Gordon, E.M., Anderson, W.F. and Parekh, D., Gene therapy for primary and metastatic pancreatic cancer with intraperitoneal retroviral vector bearing the wild-type p53 gene. Surgery 1998, 124: 143-150.
-
(1998)
Surgery
, vol.124
, pp. 143-150
-
-
Hwang, R.F.1
Gordon, E.M.2
Anderson, W.F.3
Parekh, D.4
-
54
-
-
0030996607
-
Mechanism of 'bystander effect' killing in the herpes simplex thimidine kinase gene therapy model of cancer treatment
-
Ishii-Morita, H., Mechanism of 'bystander effect' killing in the herpes simplex thimidine kinase gene therapy model of cancer treatment. Gene Ther. 1997, 4: 244-251.
-
(1997)
Gene Ther.
, vol.4
, pp. 244-251
-
-
Ishii-Morita, H.1
-
55
-
-
0038805302
-
Immunity to adenovirus and adeno-associated viral vectors: Implications for gene therapy
-
Jooss, K. and Chirmule, N., Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy. Gene Ther. 2003, 10: 955-963.
-
(2003)
Gene Ther.
, vol.10
, pp. 955-963
-
-
Jooss, K.1
Chirmule, N.2
-
56
-
-
0035138403
-
Usefulness of repeated direct intratumoral gene transfer using hemagglutinating virus of Japan-liposome method for cytosine deaminase suicide gene therapy
-
Kanyama, H., Tomita, N., Yamano, T., Aihara, T., Miyoshi, Y., Ohue, M., Sekimoto, M., Salita, I., Tamaki, Y., Kaneda, Y., Senter, P.D. and Monden, M., Usefulness of repeated direct intratumoral gene transfer using hemagglutinating virus of Japan-liposome method for cytosine deaminase suicide gene therapy. Cancer Res. 2001, 61: 14-18.
-
(2001)
Cancer Res.
, vol.61
, pp. 14-18
-
-
Kanyama, H.1
Tomita, N.2
Yamano, T.3
Aihara, T.4
Miyoshi, Y.5
Ohue, M.6
Sekimoto, M.7
Salita, I.8
Tamaki, Y.9
Kaneda, Y.10
Senter, P.D.11
Monden, M.12
-
57
-
-
1542677822
-
Novel gene therapy approaches to pancreatic cancer
-
Katz, M.H. and Bouvet, M., Novel gene therapy approaches to pancreatic cancer. Int. J. Gastrointestinal Cancer 2003, 33: 89-97.
-
(2003)
Int. J. Gastrointestinal Cancer
, vol.33
, pp. 89-97
-
-
Katz, M.H.1
Bouvet, M.2
-
58
-
-
2942536487
-
Invasion and metastasis in pancreatic cancer
-
Keleg, S., Buchler, P., Ludwig, R., Buchler, M.W. and Friess, H., Invasion and metastasis in pancreatic cancer. Mol. Cancer 2003, 2: 14.
-
(2003)
Mol. Cancer
, vol.2
, pp. 14
-
-
Keleg, S.1
Buchler, P.2
Ludwig, R.3
Buchler, M.W.4
Friess, H.5
-
59
-
-
6044219994
-
Ribozyme against mutant k-ras mRNA suppresses tumor growth of pancreatic cancer
-
Kijima, H., Yamazaki, H., Nakamura, M., Scanlon, K.J., Osamura, R.Y. and Ueyama, Y., Ribozyme against mutant k-ras mRNA suppresses tumor growth of pancreatic cancer. Int. J. Oncol. 2004, 24: 559-564.
-
(2004)
Int. J. Oncol.
, vol.24
, pp. 559-564
-
-
Kijima, H.1
Yamazaki, H.2
Nakamura, M.3
Scanlon, K.J.4
Osamura, R.Y.5
Ueyama, Y.6
-
60
-
-
0032486226
-
Loss of tumorigenicity of human pancreatic carcinoma cells engineered to produce interleukin-2 or interleukin-4 in nude mice: A potentiality for cancer gene therapy
-
Kimura, M., Tagawa, M., Takenaga, K., Kondo, F., Yamaguchi, T., Saisho, H., Nakagawara, A. and Sakiyama, S., Loss of tumorigenicity of human pancreatic carcinoma cells engineered to produce interleukin-2 or interleukin-4 in nude mice: a potentiality for cancer gene therapy. Cancer Let. 1998, 128: 47-53.
-
(1998)
Cancer Let.
, vol.128
, pp. 47-53
-
-
Kimura, M.1
Tagawa, M.2
Takenaga, K.3
Kondo, F.4
Yamaguchi, T.5
Saisho, H.6
Nakagawara, A.7
Sakiyama, S.8
-
61
-
-
0032817103
-
Acquired immunity in nude mice induced by expression of the IL-2 or IL-4 gene in human pancreatic carcinoma cells and anti-tumor effect generated by in vivo gene transfer using retrovirus
-
Kimura, M., Yoshida, Y., Narita, M., Takenaga, K., Takenouchi, T., Yamaguchi, T., Saisho, H., Sakiyama, S. and Tagawa, M., Acquired immunity in nude mice induced by expression of the IL-2 or IL-4 gene in human pancreatic carcinoma cells and anti-tumor effect generated by in vivo gene transfer using retrovirus. Int. J. Cancer 1999, 82: 549-555.
-
(1999)
Int. J. Cancer
, vol.82
, pp. 549-555
-
-
Kimura, M.1
Yoshida, Y.2
Narita, M.3
Takenaga, K.4
Takenouchi, T.5
Yamaguchi, T.6
Saisho, H.7
Sakiyama, S.8
Tagawa, M.9
-
62
-
-
10744230081
-
Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma
-
Kishida, T., Asada, H., Itokawa, Y., Cui, F.-D., Shin-Ya, M., Gojo, S., Yasutomi, K., Ueda, Y., Yamagishi, H., Imanishi, J. and Mazda, O., Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma. Mol. Ther. 2003, 8: 552-558.
-
(2003)
Mol. Ther.
, vol.8
, pp. 552-558
-
-
Kishida, T.1
Asada, H.2
Itokawa, Y.3
Cui, F.-D.4
Shin-Ya, M.5
Gojo, S.6
Yasutomi, K.7
Ueda, Y.8
Yamagishi, H.9
Imanishi, J.10
Mazda, O.11
-
63
-
-
0033521860
-
Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes
-
Kita, K., Saito, S., Morioka, C.Y. and Watanabe, A., Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes. Int. J. Cancer 1999, 80: 553-558.
-
(1999)
Int. J. Cancer
, vol.80
, pp. 553-558
-
-
Kita, K.1
Saito, S.2
Morioka, C.Y.3
Watanabe, A.4
-
64
-
-
0033233277
-
pP16INK4a expression adenovirus vector to suppress pancreas cancer cell proliferation
-
Kobayashi, S., Shirasawa, H., Sashiyama, H., Kawahira, H., Kaneko, K., Asano, T. and Ochiai, T., pP16INK4a expression adenovirus vector to suppress pancreas cancer cell proliferation. Clin. Cancer Res. 1999, 5: 4182-4185.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 4182-4185
-
-
Kobayashi, S.1
Shirasawa, H.2
Sashiyama, H.3
Kawahira, H.4
Kaneko, K.5
Asano, T.6
Ochiai, T.7
-
65
-
-
0037299714
-
Recombinant toxins for the treatment of cancer
-
Kreitman, R.J., Recombinant toxins for the treatment of cancer. Curr. Opin. Mol. Ther. 2003, 5: 44-51.
-
(2003)
Curr. Opin. Mol. Ther.
, vol.5
, pp. 44-51
-
-
Kreitman, R.J.1
-
66
-
-
0037224990
-
Intra arterial instillation of microencapsulated, ifosfamide-activating cells in the pig pancreas for chemotherapeutic targeting
-
Kroger, J-C., Benz, S., Hoffmeyer, A., Bago, Z., Bergmeister, H., Gunzburg, W.H., Karle, P., Kloppel, G., Losert, U., Muller, P., Nizze, H., Obermaier, R., Probst, A., Renner, M., Saller, R., Salmons, B., Schwendenwein, I., von Rombs, K., Weissner, R., Wagner, T., Hauenstein, K. and Lohr, M., Intra arterial instillation of microencapsulated, ifosfamide-activating cells in the pig pancreas for chemotherapeutic targeting. Pancreatology 2003, 3: 55-63.
-
(2003)
Pancreatology
, vol.3
, pp. 55-63
-
-
Kroger, J.-C.1
Benz, S.2
Hoffmeyer, A.3
Bago, Z.4
Bergmeister, H.5
Gunzburg, W.H.6
Karle, P.7
Kloppel, G.8
Losert, U.9
Muller, P.10
Nizze, H.11
Obermaier, R.12
Probst, A.13
Renner, M.14
Saller, R.15
Salmons, B.16
Schwendenwein, I.17
Von Rombs, K.18
Weissner, R.19
Wagner, T.20
Hauenstein, K.21
Lohr, M.22
more..
-
67
-
-
0030028301
-
The gap junction communication channel
-
Kumar, N.M. and Gilula, N.B., The gap junction communication channel. Cell 1996, 84: 381-388.
-
(1996)
Cell
, vol.84
, pp. 381-388
-
-
Kumar, N.M.1
Gilula, N.B.2
-
68
-
-
0032930673
-
Cytosine deaminase/5-fluorocytosine gene therapy can induce efficient anti-tumor effects and protective immunity in immunocompetent mice but not in athymic nude mice
-
Kuriyama, S., Kikukawa, M., Masui, K., Okuda, H., Nakatani, T., Sakamoto, T., Yoshiji, H., Fukui, H., Ikenaka, K., Mullen, C.A. and Tsujii, T., Cytosine deaminase/5-fluorocytosine gene therapy can induce efficient anti-tumor effects and protective immunity in immunocompetent mice but not in athymic nude mice. Int. J. Cancer 1999, 81: 592-597.
-
(1999)
Int. J. Cancer
, vol.81
, pp. 592-597
-
-
Kuriyama, S.1
Kikukawa, M.2
Masui, K.3
Okuda, H.4
Nakatani, T.5
Sakamoto, T.6
Yoshiji, H.7
Fukui, H.8
Ikenaka, K.9
Mullen, C.A.10
Tsujii, T.11
-
69
-
-
0032717286
-
Comparison of gene therapy with the herpes simplex virus thymidine kinase gene and the bacterial cytosine deaminase gene for the treatment of hepatocellular carcinoma
-
Kuriyama, S., Minoro, A., Yamazaki, M., Tsujinoue, H., Nakatani, T., Akahane, T., Toyokawa, Y., Kojima, H., Okamoto, S. and Fukui, H., Comparison of gene therapy with the herpes simplex virus thymidine kinase gene and the bacterial cytosine deaminase gene for the treatment of hepatocellular carcinoma. Scand. J. Gastroenterol. 1999, 34: 1033-1041.
-
(1999)
Scand. J. Gastroenterol.
, vol.34
, pp. 1033-1041
-
-
Kuriyama, S.1
Minoro, A.2
Yamazaki, M.3
Tsujinoue, H.4
Nakatani, T.5
Akahane, T.6
Toyokawa, Y.7
Kojima, H.8
Okamoto, S.9
Fukui, H.10
-
70
-
-
0026500701
-
Ki-ras oncogene activation in preinvasive pancreatic cancer
-
Lemoine, N.R., Jain, S., Hughes, C.M., Staddon, S.L., Maillet, B., Hall, P.A. and Kloppel, G., Ki-ras oncogene activation in preinvasive pancreatic cancer. Gastroenterology 1992, 102: 230-236.
-
(1992)
Gastroenterology
, vol.102
, pp. 230-236
-
-
Lemoine, N.R.1
Jain, S.2
Hughes, C.M.3
Staddon, S.L.4
Maillet, B.5
Hall, P.A.6
Kloppel, G.7
-
71
-
-
1342302487
-
Frequent p16INK4A/CDKN2A alterations in chemically induced Syrian golden hamster pancreatic tumors
-
Li, J., Weghorst, C.M., Tsutsumi, M., Poi, M.J., Knobloch, T.J., Casto, B.C., Melvin, W.S., Tsai, M.D. and Muscarella, P., Frequent p16INK4A/CDKN2A alterations in chemically induced Syrian golden hamster pancreatic tumors. Carcinogenesis 2004, 25: 263-268.
-
(2004)
Carcinogenesis
, vol.25
, pp. 263-268
-
-
Li, J.1
Weghorst, C.M.2
Tsutsumi, M.3
Poi, M.J.4
Knobloch, T.J.5
Casto, B.C.6
Melvin, W.S.7
Tsai, M.D.8
Muscarella, P.9
-
72
-
-
0036570316
-
Prostate-specific expression of the diphtheria toxin Achain (DT-A): Studies of inducibility and specificity of expression of prostate-specific antigen promoter-driven DT-A adenoviral-mediated gene transfer
-
Li, Y., McCadden, J., Ferrer, F., Kniszewski, M., Carducci, M., Simons, J. and Rodriguez, R., Prostate-specific expression of the diphtheria toxin Achain (DT-A): studies of inducibility and specificity of expression of prostate-specific antigen promoter-driven DT-A adenoviral-mediated gene transfer. Cancer Res. 2002, 62: 2576-2582.
-
(2002)
Cancer Res.
, vol.62
, pp. 2576-2582
-
-
Li, Y.1
McCadden, J.2
Ferrer, F.3
Kniszewski, M.4
Carducci, M.5
Simons, J.6
Rodriguez, R.7
-
73
-
-
0030690337
-
Dual role of the Smad4/DPC4 tumor suppressor in TGF -inducible transcriptional complexes
-
Liu, F., Pouponnot, C. and Massaguè, J., Dual role of the Smad4/DPC4 tumor suppressor in TGF -inducible transcriptional complexes. Genes Dev. 1997, 11: 3157-3167.
-
(1997)
Genes Dev.
, vol.11
, pp. 3157-3167
-
-
Liu, F.1
Pouponnot, C.2
Massaguè, J.3
-
74
-
-
0037457895
-
Potent antitumor activity of a urokinase-activated engineered anthrax toxin
-
Liu, S., Aaronson, H., Mitola, D.J., Leppla, S.H. and Bugge, T.H., Potent antitumor activity of a urokinase-activated engineered anthrax toxin. Proc. Natl. Acad. Sci. USA 2003, 100: 657-662.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 657-662
-
-
Liu, S.1
Aaronson, H.2
Mitola, D.J.3
Leppla, S.H.4
Bugge, T.H.5
-
75
-
-
0035947634
-
Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent antral toxin
-
Liu, S., Bugge, T.H. and Leppla, S.H., Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent antral toxin. J. Biol. Chem. 2001, 276: 17976-17984.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17976-17984
-
-
Liu, S.1
Bugge, T.H.2
Leppla, S.H.3
-
76
-
-
0037447150
-
A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells
-
Liu, T.F., Cohen, K.A., Ramage, J.G., Willingham, M.C., Thorburn, A.M. and Frankel, A.E., A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells. Cancer Res. 2003, 63: 1834-1837.
-
(2003)
Cancer Res.
, vol.63
, pp. 1834-1837
-
-
Liu, T.F.1
Cohen, K.A.2
Ramage, J.G.3
Willingham, M.C.4
Thorburn, A.M.5
Frankel, A.E.6
-
77
-
-
0342467852
-
Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma
-
Lohr, M., Hoffmeyer, A., Kroger, J.-C., Freund, M., Hain, J., Holle, A., Karle, P., Knofel, W.T., Liebe, S., Muller, P., Nizze, H., Renner, M., Saller, R.M., Wagner, T., Hauenstein, K., Gunzburg, W.H. and Salmons, B., Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma. Lancet 2001, 357: 1591-1592.
-
(2001)
Lancet
, vol.357
, pp. 1591-1592
-
-
Lohr, M.1
Hoffmeyer, A.2
Kroger, J.-C.3
Freund, M.4
Hain, J.5
Holle, A.6
Karle, P.7
Knofel, W.T.8
Liebe, S.9
Muller, P.10
Nizze, H.11
Renner, M.12
Saller, R.M.13
Wagner, T.14
Hauenstein, K.15
Gunzburg, W.H.16
Salmons, B.17
-
78
-
-
7344268645
-
Targeted chemotherapy by intratumour injection of encapsulated cells engineered to produce CYP2B1, an ifosfamide activating cytochrome P450
-
Lohr, M., Muller, P., Karle, P., Stange, J., Mitzner, S., Jesnowski, R., Nizze, H., Nebe, B., Liebe, S., Salmons, B. and Gunzburg, W.H., Targeted chemotherapy by intratumour injection of encapsulated cells engineered to produce CYP2B1, an ifosfamide activating cytochrome P450. Gene Ther. 1998; 5: 1070-1078.
-
(1998)
Gene Ther.
, vol.5
, pp. 1070-1078
-
-
Lohr, M.1
Muller, P.2
Karle, P.3
Stange, J.4
Mitzner, S.5
Jesnowski, R.6
Nizze, H.7
Nebe, B.8
Liebe, S.9
Salmons, B.10
Gunzburg, W.H.11
-
79
-
-
0038387494
-
5-fluorouracil: Mechanisms of action and clinical strategies
-
Longley D.B., Harkin, D.P. and Johnston, P.G., 5-fluorouracil: mechanisms of action and clinical strategies. Nat. Rev. Cancer 2003, 3: 330-338.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
80
-
-
0344061528
-
The K-ras mutation pattern in pancreatic ductal adenocarcinoma usually is identical to that in associated normal, hyperplastic, and metaplastic ductal epithelium
-
Luttges, J., Schlehe, B., Menke, M.A., Vogel, I., Henne-Bruns, D. and Kloppel, G., The K-ras mutation pattern in pancreatic ductal adenocarcinoma usually is identical to that in associated normal, hyperplastic, and metaplastic ductal epithelium. Cancer 1999, 85: 1703-1710.
-
(1999)
Cancer
, vol.85
, pp. 1703-1710
-
-
Luttges, J.1
Schlehe, B.2
Menke, M.A.3
Vogel, I.4
Henne-Bruns, D.5
Kloppel, G.6
-
81
-
-
0034279164
-
Evaluation of herpes simplex thymidine kinase mediated gene therapy in experimental pancreatic cancer
-
Makinen, K., Loimas, S., Wahlfors, J., Alhava, E. and Janne, J., Evaluation of herpes simplex thymidine kinase mediated gene therapy in experimental pancreatic cancer. J. Gene Med. 2000, 2: 361-367.
-
(2000)
J. Gene Med.
, vol.2
, pp. 361-367
-
-
Makinen, K.1
Loimas, S.2
Wahlfors, J.3
Alhava, E.4
Janne, J.5
-
82
-
-
0034988184
-
The epidermal growth factor receptor as a target for cancer therapy
-
Mendelsohn, J., The epidermal growth factor receptor as a target for cancer therapy. Endocrine-Rel. Cancer 2001, 8: 3-9.
-
(2001)
Endocrine-Rel. Cancer
, vol.8
, pp. 3-9
-
-
Mendelsohn, J.1
-
83
-
-
0033900009
-
Bystander effects in herpes simplex virus-thimidine kinase/ganciclovir cancer gene therapy: Role of gap-junctional intercellular communication
-
Mesnil, M. and Yamasaki, H., Bystander effects in herpes simplex virus-thimidine kinase/ganciclovir cancer gene therapy: role of gap-junctional intercellular communication. Cancer Res. 2000, 60: 3989-3999.
-
(2000)
Cancer Res.
, vol.60
, pp. 3989-3999
-
-
Mesnil, M.1
Yamasaki, H.2
-
84
-
-
0142119195
-
Recombinant toxin DAB(389)EGF is cytotoxic to human pancreatic cancer cells
-
Mishra, G., Liu, T.F. and Frankel, A.E., Recombinant toxin DAB(389)EGF is cytotoxic to human pancreatic cancer cells. Export. Opin. Biol. Ther. 2003, 3: 1173-1180.
-
(2003)
Export. Opin. Biol. Ther.
, vol.3
, pp. 1173-1180
-
-
Mishra, G.1
Liu, T.F.2
Frankel, A.E.3
-
85
-
-
0035207991
-
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4
-
Moore, P.S., Sipos, B., Orlandini, S., Sorio, C., Real, F.X., Lemoine, N.R., Gress, T., Bassi, C., Kloppel, G., Kalthoff, H., Ungefroren, H., Lohr, M. and Scarpa, A., Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. Virch. Arch. 2001, 439: 798-802.
-
(2001)
Virch. Arch.
, vol.439
, pp. 798-802
-
-
Moore, P.S.1
Sipos, B.2
Orlandini, S.3
Sorio, C.4
Real, F.X.5
Lemoine, N.R.6
Gress, T.7
Bassi, C.8
Kloppel, G.9
Kalthoff, H.10
Ungefroren, H.11
Lohr, M.12
Scarpa, A.13
-
86
-
-
0033038501
-
Cationic lipid-mediated transfection of cells in culture requires mitotic activity
-
Mortimer, I., Tam, P., MacLachlan, I., Graham, R.W., Saravolac, E.G. and Joshi, P.B., Cationic lipid-mediated transfection of cells in culture requires mitotic activity. Gene Ther. 1999, 6: 403-411.
-
(1999)
Gene Ther.
, vol.6
, pp. 403-411
-
-
Mortimer, I.1
Tam, P.2
MacLachlan, I.3
Graham, R.W.4
Saravolac, E.G.5
Joshi, P.B.6
-
87
-
-
0035076823
-
Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovinis (ONYX-015) into primary carcinomas of the pancreas: A phase I trial
-
Mulvihill, S., Warren, R., Venook, A., Adler, A., Randlev, B., Heise, C. and Kirn, D., Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovinis (ONYX-015) into primary carcinomas of the pancreas: a phase I trial. Gene Ther. 2001, 8: 308-315.
-
(2001)
Gene Ther.
, vol.8
, pp. 308-315
-
-
Mulvihill, S.1
Warren, R.2
Venook, A.3
Adler, A.4
Randlev, B.5
Heise, C.6
Kirn, D.7
-
88
-
-
0035553610
-
Antisense oligonucleotides specific to mutated k-ras genes inhibit invasiveness of human pancreatic cancer cell lines
-
Nakada, Y., Saito, S., Ohzawa, K., Morioka, C.Y., Kita, K., Minemura, M., Takahara, T. and Watanabe, A., Antisense oligonucleotides specific to mutated k-ras genes inhibit invasiveness of human pancreatic cancer cell lines. Pancreatology 2001, 1: 314-319.
-
(2001)
Pancreatology
, vol.1
, pp. 314-319
-
-
Nakada, Y.1
Saito, S.2
Ohzawa, K.3
Morioka, C.Y.4
Kita, K.5
Minemura, M.6
Takahara, T.7
Watanabe, A.8
-
89
-
-
0000421475
-
Factors limiting adenovirus-mediated gene transfer into human lung and pancreatic cancer cell lines
-
Pearson, S.A., Koch, P.E., Atkinson, N., Xiong, M., Finberg, R.W., Roth, J.A. and Fang, B., Factors limiting adenovirus-mediated gene transfer into human lung and pancreatic cancer cell lines. Clin. Cancer Res. 1999, 5: 4208-4213.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 4208-4213
-
-
Pearson, S.A.1
Koch, P.E.2
Atkinson, N.3
Xiong, M.4
Finberg, R.W.5
Roth, J.A.6
Fang, B.7
-
90
-
-
0036848885
-
Suppression of tumorigenesis and induction of p 15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells
-
Peng, B., Fleming, J.B., Breslin, T., Grau, A.M., Fojioka, S., Abbruzzese, J.L., Evans, D.B., Ayers, D., Wathen, K., Wu, T., Robertson, K.D. and Chiao, P.J., Suppression of tumorigenesis and induction of p 15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. Clin. Cancer Res. 2002, 8: 3628-3638.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3628-3638
-
-
Peng, B.1
Fleming, J.B.2
Breslin, T.3
Grau, A.M.4
Fojioka, S.5
Abbruzzese, J.L.6
Evans, D.B.7
Ayers, D.8
Wathen, K.9
Wu, T.10
Robertson, K.D.11
Chiao, P.J.12
-
91
-
-
0036798893
-
Regulated expression of diphtheria toxin in prostate cancer cells
-
Peng, W., Vverbitsky, A., Bao, Y. and Sawicki, J.A., Regulated expression of diphtheria toxin in prostate cancer cells. Mol. Ther. 2002, 6: 527-545.
-
(2002)
Mol. Ther.
, vol.6
, pp. 527-545
-
-
Peng, W.1
Vverbitsky, A.2
Bao, Y.3
Sawicki, J.A.4
-
92
-
-
0036631908
-
PG13 packaging cells produce recombinant retroviruses carrying a diphtheria toxin mutant which kills cancer cells
-
Qiao, J. and Caruso, M., PG13 packaging cells produce recombinant retroviruses carrying a diphtheria toxin mutant which kills cancer cells. J. Virol. 2002, 76: 7343-7348.
-
(2002)
J. Virol.
, vol.76
, pp. 7343-7348
-
-
Qiao, J.1
Caruso, M.2
-
93
-
-
0035873947
-
-
I
-
Reni, M., Passani, P., Panucci, M.G., Nicoletti, R., Ggalli, L., Balzano, G., Zerbi, A., Di Carlo, V. and Villa, E., Definitive results of phase II trial of cisplatin, epirubicin, continuous-infusion fluorouracil, and gemcitabine in stage IV pancreatic adenocarcinoma. I2001, 19: 2679-2686.
-
(2001)
Definitive Results of Phase II Trial of Cisplatin, Epirubicin, Continuous-infusion Fluorouracil, and Gemcitabine in Stage IV Pancreatic Adenocarcinoma
, vol.19
, pp. 2679-2686
-
-
Reni, M.1
Passani, P.2
Panucci, M.G.3
Nicoletti, R.4
Ggalli, L.5
Balzano, G.6
Zerbi, A.7
Di Carlo, V.8
Villa, E.9
-
94
-
-
0032806082
-
Genetic prodrug activation therapy for pancreatic cancer
-
Rigg, A.S. and Lemoine, N.R., Genetic prodrug activation therapy for pancreatic cancer. Ann. N.Y. Acad. Sci. USA 1999, 880: 319-325.
-
(1999)
Ann. N.Y. Acad. Sci. USA
, vol.880
, pp. 319-325
-
-
Rigg, A.S.1
Lemoine, N.R.2
-
95
-
-
0037296357
-
The epidermal growth factor receptor-tyrosine kinase: A promising therapeutic target in solid tumors
-
Ritter, C.A. and Arteaga, C.L., The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors. Sem. Oncol. 2003, 30: 3-11.
-
(2003)
Sem. Oncol.
, vol.30
, pp. 3-11
-
-
Ritter, C.A.1
Arteaga, C.L.2
-
96
-
-
0033541523
-
Gene therapy for pancreatic carcinoma: Local and distant antitumor effects after somatostatin receptor sst2 gene transfer
-
Rochaix, P., Delesque, N., Estève, J.-P., Saint-Laurent, N., Voigt, J.-J., Vaysse, N., Susini, C. and Buscail, L., Gene therapy for pancreatic carcinoma: local and distant antitumor effects after somatostatin receptor sst2 gene transfer. Hum. Gene Ther. 1999, 10: 995-1008.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 995-1008
-
-
Rochaix, P.1
Delesque, N.2
Estève, J.-P.3
Saint-Laurent, N.4
Voigt, J.-J.5
Vaysse, N.6
Susini, C.7
Buscail, L.8
-
97
-
-
0038277091
-
pP73 is effective in p53-null pancreatic cancer cells resistant to wild-type XP53 gene replacement
-
Rodicker, F. and Putzer, B.M., pP73 is effective in p53-null pancreatic cancer cells resistant to wild-type XP53 gene replacement. Cancer Res. 2003, 63: 2737-2741.
-
(2003)
Cancer Res.
, vol.63
, pp. 2737-2741
-
-
Rodicker, F.1
Putzer, B.M.2
-
98
-
-
0031424456
-
Pancreatic carcinoma cell killing via adenoviral mediated delivery of herpes simplex virus thymidine kinase gene
-
Rosenfeld, M.E., Vickers, S.M., Raben, D., Wang, M., Sampson, L., Feng, M., Jaffee, E. and Curiel, D.T., Pancreatic carcinoma cell killing via adenoviral mediated delivery of herpes simplex virus thymidine kinase gene. Ann. Surg. 1997, 5: 609-620.
-
(1997)
Ann. Surg.
, vol.5
, pp. 609-620
-
-
Rosenfeld, M.E.1
Vickers, S.M.2
Raben, D.3
Wang, M.4
Sampson, L.5
Feng, M.6
Jaffee, E.7
Curiel, D.T.8
-
99
-
-
0036809020
-
Phase II trial of 5-fluorouracil plus eniluracil in patients with advanced pancreatic cancer: A Southwest Oncology Group study
-
Rothenberg, M.L., Benedetti, J.K., Macdonald, J.S., Seay T.E., Neubauer, G.C.S., Tanaka, M.S. Jr, Giguere, J.K., Pruitt, B.T. and Abruzzese, J.L., Phase II trial of 5-fluorouracil plus eniluracil in patients with advanced pancreatic cancer: a Southwest Oncology Group study. Ann. Oncol. 2002; 13: 1576-1582.
-
(2002)
Ann. Oncol.
, vol.13
, pp. 1576-1582
-
-
Rothenberg, M.L.1
Benedetti, J.K.2
Macdonald, J.S.3
Seay, T.E.4
Neubauer, G.C.S.5
Tanaka Jr., M.S.6
Giguere, J.K.7
Pruitt, B.T.8
Abruzzese, J.L.9
-
100
-
-
0034915984
-
The future of human gene therapy
-
Rubanyi, G.M., The future of human gene therapy. Mol Aspects Med. 2001, 22: 113-142.
-
(2001)
Mol Aspects Med.
, vol.22
, pp. 113-142
-
-
Rubanyi, G.M.1
-
102
-
-
1642312315
-
Genetic alterations in pancreatic carcinoma
-
Schneider, G. and Schmid, R.M., Genetic alterations in pancreatic carcinoma. Mol. Cancer 2003, 2: 15.
-
(2003)
Mol. Cancer
, vol.2
, pp. 15
-
-
Schneider, G.1
Schmid, R.M.2
-
103
-
-
12944315074
-
Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis
-
Schwarte-Waldhoff, I., Volpert, O.V., Bouck, N.P., Sipos, B., Hahn, S.A., Klein-Scory S., Luttges, J., Kloppel, G., Graeven, U., Eilert-Micus, C., Hintelmann, A. and Schmiegel, W., Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis. Proc. Natl. Acad. Sci. USA 2000, 97: 9624-9629.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9624-9629
-
-
Schwarte-Waldhoff, I.1
Volpert, O.V.2
Bouck, N.P.3
Sipos, B.4
Hahn, S.A.5
Klein-Scory, S.6
Luttges, J.7
Kloppel, G.8
Graeven, U.9
Eilert-Micus, C.10
Hintelmann, A.11
Schmiegel, W.12
-
104
-
-
0025919690
-
Cytotoxic properties of DAB486EGF and DAB389EGF, epidermal growth factor (EGF) receptor-targeted fusion toxins
-
Shaw, J., Akiyoshi, D.E., Arrigo, D.A., Rhoad, A.E., Sullivan, B., Thomas, J., Genbauffe, F.S., Bacha, P. and Nichols, J.C., Cytotoxic properties of DAB486EGF and DAB389EGF, epidermal growth factor (EGF) receptor-targeted fusion toxins. J. Biol. Chem. 1991, 266: 21118-21124.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 21118-21124
-
-
Shaw, J.1
Akiyoshi, D.E.2
Arrigo, D.A.3
Rhoad, A.E.4
Sullivan, B.5
Thomas, J.6
Genbauffe, F.S.7
Bacha, P.8
Nichols, J.C.9
-
105
-
-
0036057585
-
Acquired resistance of pancreatic cancer towards 5-fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes
-
Shi, X., Liu, S., Kleeff, J., Friess, H. and Buchler, M.W., Acquired resistance of pancreatic cancer towards 5-fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes. Oncology 2002, 62: 354-362.
-
(2002)
Oncology
, vol.62
, pp. 354-362
-
-
Shi, X.1
Liu, S.2
Kleeff, J.3
Friess, H.4
Buchler, M.W.5
-
106
-
-
0032851547
-
Cytotoxicity of adenoviral-mediated cytosine deaminasei plus 5-fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell carcinoma model
-
Shirakawa, T., Gardner, T.A., Ko, S.-C., Bander, N., Woo, S., Gotoh, A., Kamidono, S., Chung, L.W.K. and Kao, C., Cytotoxicity of adenoviral-mediated cytosine deaminasei plus 5-fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell carcinoma model. J. Urol. 1999, 162: 949-954.
-
(1999)
J. Urol.
, vol.162
, pp. 949-954
-
-
Shirakawa, T.1
Gardner, T.A.2
Ko, S.-C.3
Bander, N.4
Woo, S.5
Gotoh, A.6
Kamidono, S.7
Chung, L.W.K.8
Kao, C.9
-
107
-
-
0031027559
-
Recurrence after resection for ductal adenocarcinoma of the pancreas
-
Sperti, C., Pasquali, C., Piccoli, A. and Pedrazzoli, S., Recurrence after resection for ductal adenocarcinoma of the pancreas. World J. Surg. 1997, 21: 195-200.
-
(1997)
World J. Surg.
, vol.21
, pp. 195-200
-
-
Sperti, C.1
Pasquali, C.2
Piccoli, A.3
Pedrazzoli, S.4
-
108
-
-
0035964399
-
A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells
-
Su, Z., Lebedeva, I.V., Gopalkrishnan, R.V., Goldstein, N.I., Stein, C.A., Reed, J.C., Dent, P. and Fisher, P.B., A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells. Proc. Natl. Acad. Sci. USA 2001, 98: 10332-10337.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10332-10337
-
-
Su, Z.1
Lebedeva, I.V.2
Gopalkrishnan, R.V.3
Goldstein, N.I.4
Stein, C.A.5
Reed, J.C.6
Dent, P.7
Fisher, P.B.8
-
109
-
-
0034932057
-
Systemic IFN-β gene therapy results in long-term survival in mice with established colorectal liver metastases
-
Tada, H., Maron, D.J., Choi, E.A., Barsoum, J., Lei, H., Xie, Q., Liu, W., Ellis, L., Moscioni, A.D., Tazelaar, J., Fawell, S., Qin, X., Propert, K.J., Davis, A., Fraker, D.L., Wilson, J.M. and Spitz, F.R., Systemic IFN-β gene therapy results in long-term survival in mice with established colorectal liver metastases. J. Clin. Invest. 2001, 108: 83-95.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 83-95
-
-
Tada, H.1
Maron, D.J.2
Choi, E.A.3
Barsoum, J.4
Lei, H.5
Xie, Q.6
Liu, W.7
Ellis, L.8
Moscioni, A.D.9
Tazelaar, J.10
Fawell, S.11
Qin, X.12
Propert, K.J.13
Davis, A.14
Fraker, D.L.15
Wilson, J.M.16
Spitz, F.R.17
-
110
-
-
0030050945
-
Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease
-
Tada, M., Ohashi, M., Shiratori, Y., Okudaira, T., Komatsu, Y., Kawabe, T., Yoshida, H., Machinami, R., Kishi, K. and Omata, M., Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease. Gastroenterology 1996, 110: 227-231.
-
(1996)
Gastroenterology
, vol.110
, pp. 227-231
-
-
Tada, M.1
Ohashi, M.2
Shiratori, Y.3
Okudaira, T.4
Komatsu, Y.5
Kawabe, T.6
Yoshida, H.7
Machinami, R.8
Kishi, K.9
Omata, M.10
-
111
-
-
0032693659
-
High proportion of mutant K-ras gene in pancreatic juice of patients with pancreatic cystic lesions
-
Tateishi, K., Tada, M., Yamagata, M., Isayama, H., Komatsu, Y., Kawabe, T., Shiratori, Y. and Omata, M., High proportion of mutant K-ras gene in pancreatic juice of patients with pancreatic cystic lesions. Gut 1999, 45: 737-740.
-
(1999)
Gut
, vol.45
, pp. 737-740
-
-
Tateishi, K.1
Tada, M.2
Yamagata, M.3
Isayama, H.4
Komatsu, Y.5
Kawabe, T.6
Shiratori, Y.7
Omata, M.8
-
113
-
-
0033624988
-
Adenovirus-mediated anti-K-ras ribozyme induces apoptosis and growth suppression of human pancreatic carcinoma
-
Tsuchida, T., Kijima, H., Hori, S., Oshika, Y., Tokunaga, T., Kawai, K., Yamazaki, H., Ueyama, Y., Scanlon, K.J., Tamaoki, N. and Nakamura, M., Adenovirus-mediated anti-K-ras ribozyme induces apoptosis and growth suppression of human pancreatic carcinoma. Cancer Gene Ther. 2000, 7: 373-383.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 373-383
-
-
Tsuchida, T.1
Kijima, H.2
Hori, S.3
Oshika, Y.4
Tokunaga, T.5
Kawai, K.6
Yamazaki, H.7
Ueyama, Y.8
Scanlon, K.J.9
Tamaoki, N.10
Nakamura, M.11
-
114
-
-
12444328351
-
Transduction of the IL-21 and IL-23 genes in human pancreatic carcinoma cells produces natural killer cell-dependent and independent antitumor effects
-
Ugai, S.-I., Shimozato, O., Yu, L., Wang, Y.-Q., Kawamura, K., Yamamoto, H., Yamaguchi, T., Saisho, H., Sakiyama, S. and Tagawa, M., Transduction of the IL-21 and IL-23 genes in human pancreatic carcinoma cells produces natural killer cell-dependent and independent antitumor effects. Cancer Gene Ther. 2003, 10: 771-778.
-
(2003)
Cancer Gene Ther.
, vol.10
, pp. 771-778
-
-
Ugai, S.-I.1
Shimozato, O.2
Yu, L.3
Wang, Y.-Q.4
Kawamura, K.5
Yamamoto, H.6
Yamaguchi, T.7
Saisho, H.8
Sakiyama, S.9
Tagawa, M.10
-
115
-
-
0033869563
-
Flucytosine: A review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions
-
Vermes, A., Guchelaar, H.-J. and Dankert, J., Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions. JAC 2000, 46: 171-179.
-
(2000)
JAC
, vol.46
, pp. 171-179
-
-
Vermes, A.1
Guchelaar, H.-J.2
Dankert, J.3
-
116
-
-
0036828266
-
Antitumor effect of in vivo somatostatin receptor subtype 2 gene transfer in primary and metastatic pancreatic cancer models
-
Vernejoul, F., Faure, P., Benali, N., Calise, D., Tiraby, G., Pradayrol, L., Susini, C. and Buscail, L., Antitumor effect of in vivo somatostatin receptor subtype 2 gene transfer in primary and metastatic pancreatic cancer models. Cancer Res. 2002, 62: 6124-6131.
-
(2002)
Cancer Res.
, vol.62
, pp. 6124-6131
-
-
Vernejoul, F.1
Faure, P.2
Benali, N.3
Calise, D.4
Tiraby, G.5
Pradayrol, L.6
Susini, C.7
Buscail, L.8
-
117
-
-
1142263304
-
herpes simplex virus thymidine kinase and ganciclovir suicide gene therapy for human pancreatic cancer
-
Wang, J., Xiao-Xuan, L., Dao-Zhen, C., Shu-Feng, L. and Li-Shan, Z., herpes simplex virus thymidine kinase and ganciclovir suicide gene therapy for human pancreatic cancer. World J. Gastroenterol. 2004, 10: 400-403.
-
(2004)
World J. Gastroenterol.
, vol.10
, pp. 400-403
-
-
Wang, J.1
Xiao-Xuan, L.2
Dao-Zhen, C.3
Shu-Feng, L.4
Li-Shan, Z.5
-
118
-
-
1642423482
-
Specific gene expression and therapy for pancreatic cancer using the cytosine deaminase gene directed by the rat insulin promoter
-
Wang, X.-P., Yazawa, K., Yang, J., Kohn, D., Fisher, W.E. and Brunicardi, C., Specific gene expression and therapy for pancreatic cancer using the cytosine deaminase gene directed by the rat insulin promoter. J. Gastrointest. Surg. 2004, 8: 98-108.
-
(2004)
J. Gastrointest. Surg.
, vol.8
, pp. 98-108
-
-
Wang, X.-P.1
Yazawa, K.2
Yang, J.3
Kohn, D.4
Fisher, W.E.5
Brunicardi, C.6
-
119
-
-
0032937404
-
Modulation of the immune response and tumor growth by activated Ras.
-
Weijzen, S., Velders, M.P. and Kast, W.M., Modulation of the immune response and tumor growth by activated Ras. Leukemia 1999, 13: 502-513.
-
(1999)
Leukemia
, vol.13
, pp. 502-513
-
-
Weijzen, S.1
Velders, M.P.2
Kast, W.M.3
-
120
-
-
0034933606
-
Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors
-
Wesseling, J.G., Bosnia, P.J., Krasnykh, V., Kashentseva, E.A., Blackwell, J.L., Reynolds, P.N., Li, H., Parameshwar, M., Vickers, S.M., Jaffee, E.M., Huibregtse, K., Curiel, D.T. and Dmitriev, I., Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors. Gene Ther 2001, 8: 969-976.
-
(2001)
Gene Ther
, vol.8
, pp. 969-976
-
-
Wesseling, J.G.1
Bosnia, P.J.2
Krasnykh, V.3
Kashentseva, E.A.4
Blackwell, J.L.5
Reynolds, P.N.6
Li, H.7
Parameshwar, M.8
Vickers, S.M.9
Jaffee, E.M.10
Huibregtse, K.11
Curiel, D.T.12
Dmitriev, I.13
-
121
-
-
0026609066
-
Diphteria toxin and pseudomonas aeruginosa exotoxin A: Active-site, structure and enzymatic mechanism
-
Wilson, B.A. and Collier, R.J., Diphteria toxin and pseudomonas aeruginosa exotoxin A: Active-site, structure and enzymatic mechanism. Curr Top. Microbiol. Immunol. 1992, 175: 27-41.
-
(1992)
Curr Top. Microbiol. Immunol.
, vol.175
, pp. 27-41
-
-
Wilson, B.A.1
Collier, R.J.2
-
122
-
-
0037182756
-
Mdm2 inhibition of p53 induces E2F1 transactivation via p21
-
Wunderlich, M. and Berberich, S.J., Mdm2 inhibition of p53 induces E2F1 transactivation via p21. Oncogene 2002, 21: 4414-4421.
-
(2002)
Oncogene
, vol.21
, pp. 4414-4421
-
-
Wunderlich, M.1
Berberich, S.J.2
-
123
-
-
0037010091
-
Epidermal growth factor receptor-targeted therapy for pancreatic cancer
-
Xiong, H.Q. and Abbruzzese, J.L., Epidermal growth factor receptor-targeted therapy for pancreatic cancer. Sem. Oncol. 2002, 29: 31-37.
-
(2002)
Sem. Oncol.
, vol.29
, pp. 31-37
-
-
Xiong, H.Q.1
Abbruzzese, J.L.2
-
124
-
-
0026544424
-
Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney
-
Yamada, Y., Post, S.R., Wang, K., Tager, H.S., Bell, G.I. and Seino, S., Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. PNAS 1992, 89: 251-255.
-
(1992)
PNAS
, vol.89
, pp. 251-255
-
-
Yamada, Y.1
Post, S.R.2
Wang, K.3
Tager, H.S.4
Bell, G.I.5
Seino, S.6
-
125
-
-
0029794390
-
Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral herpes simplex thymidine kinase vector supernatant and ganciclovir
-
Yang, L., Hwang, R., Pandit, L., Gordon, E.M., Anderson, W.F. and Parekh, D., Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral herpes simplex thymidine kinase vector supernatant and ganciclovir. Ann. Surg. 1996, 224: 405-417.
-
(1996)
Ann. Surg.
, vol.224
, pp. 405-417
-
-
Yang, L.1
Hwang, R.2
Pandit, L.3
Gordon, E.M.4
Anderson, W.F.5
Parekh, D.6
-
126
-
-
0032549688
-
Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ ganciclovir-based gene therapy of human gastrointestinal tumor cells
-
Yiang, L., Chiang, Y., Lenz, H.-J., Danenberg, K.D., Spears, C.P., Gordon, E.M., Anderson, W.F. and Parekh, D., Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ ganciclovir-based gene therapy of human gastrointestinal tumor cells. Hum. Gene Ther. 1998, 9: 719-728.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 719-728
-
-
Yiang, L.1
Chiang, Y.2
Lenz, H.-J.3
Danenberg, K.D.4
Spears, C.P.5
Gordon, E.M.6
Anderson, W.F.7
Parekh, D.8
-
127
-
-
0031949646
-
Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene
-
Yiang, L., Hwang, R., Chiang, Y., Gordon, E.M., Anderson, W.F. and Parekh, D., Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene. Clin. Cancer Res. 1998, 4: 731-741.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 731-741
-
-
Yiang, L.1
Hwang, R.2
Chiang, Y.3
Gordon, E.M.4
Anderson, W.F.5
Parekh, D.6
-
128
-
-
0034127567
-
Impaired tumorigenicity of human pancreatic cancer cells retrovirally transduced with interleukin-12 or interleukin-15 gene
-
Yoshida, Y., Tasaki, K., Myauchi, M., Narita, M., Takenaga, K., Yamamoto, H., Yamaguchi, T., Saisho, H., Sakiyama, S. and Tagawa, M., Impaired tumorigenicity of human pancreatic cancer cells retrovirally transduced with interleukin-12 or interleukin-15 gene. Cancer Gene Ther. 2000, 7: 324-331.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 324-331
-
-
Yoshida, Y.1
Tasaki, K.2
Myauchi, M.3
Narita, M.4
Takenaga, K.5
Yamamoto, H.6
Yamaguchi, T.7
Saisho, H.8
Sakiyama, S.9
Tagawa, M.10
-
129
-
-
0034508245
-
Anti-tumorigenic effect of a K-ras ribozyme against human lung cancer cell line heterotransplants in nude mice
-
Zhang, Y.A., Nemunaitis, J., Scanlon, K.J. and Tong, A.W., Anti-tumorigenic effect of a K-ras ribozyme against human lung cancer cell line heterotransplants in nude mice. Gene Ther. 2000, 7: 2041-2050.
-
(2000)
Gene Ther.
, vol.7
, pp. 2041-2050
-
-
Zhang, Y.A.1
Nemunaitis, J.2
Scanlon, K.J.3
Tong, A.W.4
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