Systemic IFN-β gene therapy results in long-term survival in mice with established colorectal liver metastases

Journal of Clinical Investigation

Volumn 108, Issue 1, 2001, Pages 83-95

  Tada, H ^a   Maron, D J ^a   Choi, E A ^a   Barsoum, J ^a   Lei, H ^a   Xie, Q ^a   Liu, W ^a   Ellis, L ^a   Moscioni, A D ^a   Tazelaar, J ^a   Fawell, S ^a   Qin, X ^a   Propert, K J ^a   Davis, A ^a   Fraker, D L ^a   Wilson, J M ^a   Spitz, F R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; COMPLEMENTARY DNA;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GRAFT; CANCER MODEL; CANCER SURVIVAL; CANCER THERAPY; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; GENE THERAPY; HUMAN; HUMAN CELL; LIVER METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS RECOMBINANT; XENOGRAFT;

ADENOCARCINOMA; ADENOVIRIDAE; ANIMALS; APOPTOSIS; COLORECTAL NEOPLASMS; CYTOMEGALOVIRUS; DNA, COMPLEMENTARY; FEMALE; GENE THERAPY; GENES, SYNTHETIC; GENETIC VECTORS; HEPATOCYTES; HUMANS; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; INTERFERON-BETA; KILLER CELLS, NATURAL; LIVER NEOPLASMS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, NUDE; MICE, SCID; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0034932057     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200109841     Document Type: Article

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