메뉴 건너뛰기




Volumn 880, Issue , 1999, Pages 319-325

Genetic prodrug activation therapy for pancreatic cancer

Author keywords

[No Author keywords available]

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; AMYGDALIN; BENZOIC ACID DERIVATIVE; CYCLOPHOSPHAMIDE; DOXIFLURIDINE; DRUG METABOLIZING ENZYME; ETOPOSIDE; FLUCYTOSINE; GANCICLOVIR; METHOTREXATE; PRODRUG; XANTHINE;

EID: 0032806082     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb09535.x     Document Type: Conference Paper
Times cited : (8)

References (26)
  • 1
    • 0030666663 scopus 로고    scopus 로고
    • Engineering tissue-specific expression of a recombinant adenovirus: Selective transgene transcription in the pancreas using the amylase promoter
    • 1. DEMATTEO, R.P. et al. 1997. Engineering tissue-specific expression of a recombinant adenovirus: selective transgene transcription in the pancreas using the amylase promoter. J. Surg. Res. 72: 155-161.
    • (1997) J. Surg. Res. , vol.72 , pp. 155-161
    • Dematteo, R.P.1
  • 2
    • 0027477387 scopus 로고
    • In vitro and in vivo targeting of gene expression to melanoma cells
    • 2. VILE, R.G. & I.R, HART. 1993. In vitro and in vivo targeting of gene expression to melanoma cells. Cancer Res. 53: 962-967.
    • (1993) Cancer Res. , vol.53 , pp. 962-967
    • Vile, R.G.1    Hart, I.R.2
  • 3
    • 0028426915 scopus 로고
    • Gene therapy for cancer using tumor-specific prodrug activation
    • 3. HARRIS, J.D. et al. 1994. Gene therapy for cancer using tumor-specific prodrug activation. Gene Ther. 1: 170-175.
    • (1994) Gene Ther. , vol.1 , pp. 170-175
    • Harris, J.D.1
  • 4
    • 0030459592 scopus 로고    scopus 로고
    • Suicide gene expression induced in tumor cells transduced with recombinant adenoviral, retroviral and plasmid vectors containing the ERBB2 promoter
    • 4. RING, C.J.A. et al. 1996. Suicide gene expression induced in tumor cells transduced with recombinant adenoviral, retroviral and plasmid vectors containing the ERBB2 promoter. Gene Ther. 3: 1094-1103.
    • (1996) Gene Ther. , vol.3 , pp. 1094-1103
    • Ring, C.J.A.1
  • 6
    • 0021968648 scopus 로고
    • Inhibition of cellular DNA polymerase α and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(1,3-dihydroxy-2-propoxymethyl)guanine
    • 6. MAR, E.-C. et al. 1985. Inhibition of cellular DNA polymerase α and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(1,3-dihydroxy-2-propoxymethyl)guanine. J. Virol. 53: 776-780.
    • (1985) J. Virol. , vol.53 , pp. 776-780
    • Mar, E.-C.1
  • 7
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserting herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
    • 7. MOOLTON, F.L. 1986. Tumor chemosensitivity conferred by inserting herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res. 46: 5276-5281.
    • (1986) Cancer Res. , vol.46 , pp. 5276-5281
    • Moolton, F.L.1
  • 8
    • 0030686481 scopus 로고    scopus 로고
    • Adenoviral-mediated herpes simplex virus thymidine kinase gene transfer: Regression of hepatic metastasis of pancreatic tumors
    • 8. BLOCK, A. et al. 1997. Adenoviral-mediated herpes simplex virus thymidine kinase gene transfer: regression of hepatic metastasis of pancreatic tumors. Pancreas 15: 25-34.
    • (1997) Pancreas , vol.15 , pp. 25-34
    • Block, A.1
  • 9
    • 0031424456 scopus 로고    scopus 로고
    • Pancreatic carcinoma cell killing via adenoviral mediated delivery of the herpes simplex virus thymidine kinase gene
    • 9. ROSENFELD, M.E. et al. 1997. Pancreatic carcinoma cell killing via adenoviral mediated delivery of the herpes simplex virus thymidine kinase gene. Ann. Surg. 225: 609-620.
    • (1997) Ann. Surg. , vol.225 , pp. 609-620
    • Rosenfeld, M.E.1
  • 10
    • 0030757856 scopus 로고    scopus 로고
    • Gene therapy for peritoneal dissemination of pancreatic cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene
    • 10. AOKI, K. et al. 1997. Gene therapy for peritoneal dissemination of pancreatic cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene. Hum. Gene Ther. 8: 1105-1113.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 1105-1113
    • Aoki, K.1
  • 11
    • 0029794390 scopus 로고    scopus 로고
    • Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral herpes simplex thymidine kinase vector supernatant and ganciclovir
    • 11. YANG, L. et al. 1996. Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral herpes simplex thymidine kinase vector supernatant and ganciclovir. Ann. Surg. 224: 405-417.
    • (1996) Ann. Surg. , vol.224 , pp. 405-417
    • Yang, L.1
  • 12
    • 0001205907 scopus 로고
    • Tumor regression when a fraction of the tumor mass contains the HSV-TK gene
    • 12. FREEMAN, S.M. et al. 1992. Tumor regression when a fraction of the tumor mass contains the HSV-TK gene. J. Cell. Biochem. 16: 47.
    • (1992) J. Cell. Biochem. , vol.16 , pp. 47
    • Freeman, S.M.1
  • 13
    • 0027483695 scopus 로고
    • The 'bystander effect': Tumor regression when a fraction of the tumor mass is genetically modified
    • 13. FREEMAN, S.M. et al. 1993. The 'bystander effect': tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res. 53; 5274-5238.
    • (1993) Cancer Res. , vol.53 , pp. 5274-15238
    • Freeman, S.M.1
  • 14
    • 0028108469 scopus 로고
    • Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminsase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
    • 14. HUBER, B.W. et al. 1994. Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminsase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc. Natl. Acad. Sci. USA 91: 8302-8306.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8302-8306
    • Huber, B.W.1
  • 15
    • 0027787053 scopus 로고
    • In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV-tk retroviral gene therapy
    • 15. Bi, L.B. et al. 1993. In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV-tk retroviral gene therapy. Hum. Gene Ther. 4: 725-731.
    • (1993) Hum. Gene Ther. , vol.4 , pp. 725-731
    • Bi, L.B.1
  • 16
    • 0027268254 scopus 로고
    • Transport of 5-fluorouracil and uracil into human erythrocytes
    • 16. DOMAIN, B.A. et al. 1993. Transport of 5-fluorouracil and uracil into human erythrocytes. Biochem. Pharmacol. 46: 503-510.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 503-510
    • Domain, B.A.1
  • 17
    • 0029111747 scopus 로고
    • Treatment of ovarian cancer using a gene-modified vaccine
    • 17. FREEMAN, S.M. et al. 1995. Treatment of ovarian cancer using a gene-modified vaccine. Hum. Gene Ther. 6: 927-939.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 927-939
    • Freeman, S.M.1
  • 18
    • 0028071271 scopus 로고
    • The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats
    • 18. RAM, Z. et al. 1994. The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats. J. Neurosurg. 81: 256-260.
    • (1994) J. Neurosurg. , vol.81 , pp. 256-260
    • Ram, Z.1
  • 19
    • 0029074452 scopus 로고
    • The role of cytokines in mediating the bystander effect using HSV-TK xenogeneic cells
    • 19. FREEMAN, S.M. et al. 1995. The role of cytokines in mediating the bystander effect using HSV-TK xenogeneic cells. Cancer Lett. 92: 167-174.
    • (1995) Cancer Lett. , vol.92 , pp. 167-174
    • Freeman, S.M.1
  • 20
    • 0028297316 scopus 로고
    • Tumors expressing the cytosine deaminase gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild-type tumor
    • 20. MULLEN, C.A. et al. 1994. Tumors expressing the cytosine deaminase gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild-type tumor. Cancer Res. 54: 1503-1506.
    • (1994) Cancer Res. , vol.54 , pp. 1503-1506
    • Mullen, C.A.1
  • 21
    • 0028075655 scopus 로고
    • Systemic gene therapy for murine melanoma using tissue-specific expression of the HSVtk gene involves an immune component
    • 21. VILE, R.G. et al. 1994. Systemic gene therapy for murine melanoma using tissue-specific expression of the HSVtk gene involves an immune component. Cancer Res. 54: 6228-6234.
    • (1994) Cancer Res. , vol.54 , pp. 6228-6234
    • Vile, R.G.1
  • 22
    • 0031023474 scopus 로고    scopus 로고
    • Immune system in suicide gene therapy
    • 22. FREEMAN, S.M. et al. 1997. Immune system in suicide gene therapy. Lancet 349: 2-3.
    • (1997) Lancet , vol.349 , pp. 2-3
    • Freeman, S.M.1
  • 23
    • 0029878461 scopus 로고    scopus 로고
    • Treatment of microscopic pulmonary metastases with recombinant autologous tumor vaccine expressing interleukin 6 and Escherichia coli cytosine deaminase suicide genes
    • 23. MULLEN, C.A. et al. 1996. Treatment of microscopic pulmonary metastases with recombinant autologous tumor vaccine expressing interleukin 6 and Escherichia coli cytosine deaminase suicide genes. Cancer Res. 56: 1362-1366.
    • (1996) Cancer Res. , vol.56 , pp. 1362-1366
    • Mullen, C.A.1
  • 24
    • 0032529454 scopus 로고    scopus 로고
    • Suicide gene therapy of chemically induced mammary tumor in rat: Efficacy and distant bystander effect
    • 24. WEI, M.X. et al. 1998. Suicide gene therapy of chemically induced mammary tumor in rat: efficacy and distant bystander effect. Cancer Res. 58: 3529-3532.
    • (1998) Cancer Res. , vol.58 , pp. 3529-3532
    • Wei, M.X.1
  • 25
    • 0031463632 scopus 로고    scopus 로고
    • Therapy of malignant brain tumors by intratumoral injection of retroviral vector-producing cells
    • 25. RAM, Z. et al. 1998. Therapy of malignant brain tumors by intratumoral injection of retroviral vector-producing cells. Nat. Med. 3: 1354-1361.
    • (1998) Nat. Med. , vol.3 , pp. 1354-1361
    • Ram, Z.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.