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Volumn 6, Issue 4, 1999, Pages 547-553

Enhanced pancreatic tumor regression by a combination of adenovirus and retrovirus-mediated delivery of the herpes simplex virus thymidine kinase gene

Author keywords

Adenovirus; Bystander effect; HSVtk; Pancreatic tumors; Retrovirus

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE; VIRUS ENZYME;

EID: 0032959726     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300846     Document Type: Article
Times cited : (47)

References (24)
  • 2
    • 0007564867 scopus 로고    scopus 로고
    • Pancreatic cancer recent progress in diagnosis and treatment
    • Neoptolemos JP, Lemoine NR (eds). Blackwell: Oxford
    • Beger HG, Link KH, Poch B, Gansauge F. Pancreatic cancer recent progress in diagnosis and treatment. In: Neoptolemos JP, Lemoine NR (eds). Pancreatic Cancer. Molecular and Clinical Advances. Blackwell: Oxford, 1996, pp 227-235.
    • (1996) Pancreatic Cancer. Molecular and Clinical Advances , pp. 227-235
    • Beger, H.G.1    Link, K.H.2    Poch, B.3    Gansauge, F.4
  • 3
    • 0031424510 scopus 로고    scopus 로고
    • Genetic prodrug activation therapy
    • Rigg A, Sikora K. Genetic prodrug activation therapy. Mol Med Today 1997; 3: 359-366.
    • (1997) Mol Med Today , vol.3 , pp. 359-366
    • Rigg, A.1    Sikora, K.2
  • 4
    • 0002391736 scopus 로고
    • Unique spectrum of activity of 9-{(1,3-dihydroxy-2-propoxy)methyl}-guanine against herpes viruses in vitro and its mode of action against herpes symplex virus type 1
    • Cheng YC et al. Unique spectrum of activity of 9-{(1,3-dihydroxy-2-propoxy)methyl}-guanine against herpes viruses in vitro and its mode of action against herpes symplex virus type 1. Proc Natl Acad Sci USA 1983; 80: 2167-2770.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 2167-2770
    • Cheng, Y.C.1
  • 5
    • 0030140343 scopus 로고    scopus 로고
    • Gene therapy against cancer and HIV infection using the gene encoding herpes simplex virus thymidine kinase
    • Caruso M. Gene therapy against cancer and HIV infection using the gene encoding herpes simplex virus thymidine kinase. Mol Med Today 1996; 2: 212-217.
    • (1996) Mol Med Today , vol.2 , pp. 212-217
    • Caruso, M.1
  • 6
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver KW et al. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 1992; 256: 1550-1552.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1
  • 7
    • 0030100158 scopus 로고    scopus 로고
    • Prodrug-activated gene therapy: Involvement of an immunological component in the 'bystander effect'
    • Gagandeep S et al. Prodrug-activated gene therapy: involvement of an immunological component in the 'bystander effect'. Cancer Gene Ther 1996; 3: 83-88.
    • (1996) Cancer Gene Ther , vol.3 , pp. 83-88
    • Gagandeep, S.1
  • 8
    • 0029161615 scopus 로고
    • The bystander effect: Association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice
    • Colombo BM et al. The bystander effect: association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice. Hum Gene Ther 1995; 6: 763-772.
    • (1995) Hum Gene Ther , vol.6 , pp. 763-772
    • Colombo, B.M.1
  • 9
    • 0029913138 scopus 로고    scopus 로고
    • Gap junctions play a role in the bystander effect of the herpes simplex virus thymidine kinase/ganciclovir system in vitro
    • Elshami AA et al. Gap junctions play a role in the bystander effect of the herpes simplex virus thymidine kinase/ganciclovir system in vitro. Gene Therapy 1996; 3: 85-92.
    • (1996) Gene Therapy , vol.3 , pp. 85-92
    • Elshami, A.A.1
  • 10
    • 0030757097 scopus 로고    scopus 로고
    • The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions
    • Vrionis FD et al. The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions. Gene Therapy 1997; 4: 577-585.
    • (1997) Gene Therapy , vol.4 , pp. 577-585
    • Vrionis, F.D.1
  • 11
    • 0027531548 scopus 로고
    • In situ retrovirus-mediated gene transfer for the treatment of brain tumors in rats
    • Ram Z et al. In situ retrovirus-mediated gene transfer for the treatment of brain tumors in rats. Cancer Res 1993; 53: 83-88.
    • (1993) Cancer Res , vol.53 , pp. 83-88
    • Ram, Z.1
  • 12
    • 0029924404 scopus 로고    scopus 로고
    • Prostate cancer gene therapy: Herpes simplex virus thymidine kinase gene transduction followed by Ganciclovir in mouse and human prostate cancer models
    • Eastham JA et al. Prostate cancer gene therapy: herpes simplex virus thymidine kinase gene transduction followed by Ganciclovir in mouse and human prostate cancer models. Hum Gene Ther 1996; 7: 515-523.
    • (1996) Hum Gene Ther , vol.7 , pp. 515-523
    • Eastham, J.A.1
  • 13
    • 0026906987 scopus 로고
    • Adenovirus-mediated IH vivo gene transfer and expression in normal rat liver
    • Haffe HA et al. Adenovirus-mediated IH vivo gene transfer and expression in normal rat liver. Nat Genet 1992; 1: 372-378.
    • (1992) Nat Genet , vol.1 , pp. 372-378
    • Haffe, H.A.1
  • 14
    • 0027217637 scopus 로고
    • An experimental model of retrovirus gene therapy for malignant brain rumors
    • Takamiya Y et al. An experimental model of retrovirus gene therapy for malignant brain rumors. J Neurosurg 1993; 79: 104-110.
    • (1993) J Neurosurg , vol.79 , pp. 104-110
    • Takamiya, Y.1
  • 15
    • 0030775646 scopus 로고    scopus 로고
    • Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector
    • Feng M et al. Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector. Nat Biotechnol 1997; 15: 866-870.
    • (1997) Nat Biotechnol , vol.15 , pp. 866-870
    • Feng, M.1
  • 16
    • 0344435721 scopus 로고    scopus 로고
    • Characterization of new human pancreatic cancer cell lines expressing p21 and Gadd45 by p53-independent pathways
    • submitted
    • Garcia C et al. Characterization of new human pancreatic cancer cell lines expressing p21 and Gadd45 by p53-independent pathways. Cancer Res 1998 (submitted).
    • (1998) Cancer Res
    • Garcia, C.1
  • 17
    • 0030996607 scopus 로고    scopus 로고
    • Mechanism of bystander effect killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment
    • Ishii-morita H et al. Mechanism of bystander effect killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment. Gene Therapy 1997; 4: 244-251.
    • (1997) Gene Therapy , vol.4 , pp. 244-251
    • Ishii-morita, H.1
  • 18
    • 0028148134 scopus 로고
    • Directed enzyme pro-drug gene therapy for pancreatic cancer in vivo
    • DiMaio JM et al. Directed enzyme pro-drug gene therapy for pancreatic cancer in vivo. Surgery 1994; 116: 205-213.
    • (1994) Surgery , vol.116 , pp. 205-213
    • Dimaio, J.M.1
  • 19
    • 0031424456 scopus 로고    scopus 로고
    • Pancreatic carcinoma cell killing via adenoviral mediated delivery of herpes simplex virus thymidine kinase gene
    • Rosenfeld ME et al. Pancreatic carcinoma cell killing via adenoviral mediated delivery of herpes simplex virus thymidine kinase gene. Ann Surg 1997; 225: 609-620.
    • (1997) Ann Surg , vol.225 , pp. 609-620
    • Rosenfeld, M.E.1
  • 20
    • 0030918640 scopus 로고    scopus 로고
    • Establishment of parameters for optimal transduction efficiency and antitumor effects with purified high-titer HSVtk retroviral vector in established solid tumors
    • Smiley WR et al. Establishment of parameters for optimal transduction efficiency and antitumor effects with purified high-titer HSVtk retroviral vector in established solid tumors. Hum Gene Ther 1997; 8: 965-977.
    • (1997) Hum Gene Ther , vol.8 , pp. 965-977
    • Smiley, W.R.1
  • 21
    • 17344382938 scopus 로고    scopus 로고
    • Tissue-specific expression of HSVtk gene can induce efficient antitumor effect and protective immunity to wild-type hepatocellular carcinoma
    • Kuriyama S et al. Tissue-specific expression of HSVtk gene can induce efficient antitumor effect and protective immunity to wild-type hepatocellular carcinoma. Int J Cancer 1997; 71: 470-475.
    • (1997) Int J Cancer , vol.71 , pp. 470-475
    • Kuriyama, S.1
  • 22
    • 0029953781 scopus 로고    scopus 로고
    • A phase I trial of in vivo gene therapy with the herpes simplex thymidine kinase/ganciclovir system for the treatment of refractory or recurrent ovarian cancer
    • Link CJ, Moorman D. A phase I trial of in vivo gene therapy with the herpes simplex thymidine kinase/ganciclovir system for the treatment of refractory or recurrent ovarian cancer. Hum Gene Ther 1996; 7: 1161-1179.
    • (1996) Hum Gene Ther , vol.7 , pp. 1161-1179
    • Link, C.J.1    Moorman, D.2
  • 23
    • 0028690027 scopus 로고
    • Use of recombinant adenovirus for metabolic engineering of mammalian cells
    • Becker TC et al. Use of recombinant adenovirus for metabolic engineering of mammalian cells. Meth Cell Biol 1994; 43: 161-189.
    • (1994) Meth Cell Biol , vol.43 , pp. 161-189
    • Becker, T.C.1
  • 24
    • 0028860038 scopus 로고
    • Long-term rat survival after malignant brain tumor regression by retroviral gene therapy
    • Izquierdo M et al. Long-term rat survival after malignant brain tumor regression by retroviral gene therapy. Gene Therapy 1995; 2: 66-69.
    • (1995) Gene Therapy , vol.2 , pp. 66-69
    • Izquierdo, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.