Techniques: Promiscuous Gα proteins in basic research and drug discovery

Trends in Pharmacological Sciences

Volumn 26, Issue 11, 2005, Pages 595-602

  Kostenis, Evi ^a   Waelbroeck, Magali ^b   Milligan, Graeme ^c  

^a 7TM Pharma A S   (Denmark)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II DERIVATIVE; CHIMERIC PROTEIN; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; IPSAPIRONE; SEROTONIN 1A AGONIST; SEROTONIN AGONIST; G PROTEIN ALPHA 16; GNA14 PROTEIN, HUMAN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; SEROTONIN 6 RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

DRUG EFFICACY; DRUG INDUSTRY; DRUG POTENCY; DRUG RESEARCH; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; CALCIUM SIGNALING; CELL LINE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; GENETIC PROCEDURES; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BIOSENSING TECHNIQUES; CALCIUM SIGNALING; CELL LINE; DRUG DESIGN; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; TRANSFECTION;

EID: 27144434813     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2005.09.007     Document Type: Review

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