Structure of the p115RhoGEF rgRGS domain-Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator

Nature Structural and Molecular Biology

Volumn 12, Issue 2, 2005, Pages 191-197

  Chen, Zhe ^a   Singer, William D ^a   Sternweis, Paul C ^a   Sprang, Stephen R ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN SUBUNIT; RHO GUANOSINE TRIPHOSPHATASE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HYBRID PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR P115;

AMINO TERMINAL SEQUENCE; ARTICLE; CHIMERA; COMPLEX FORMATION; CONVERGENT EVOLUTION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; ELECTRICITY; GENETICS; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MOUSE; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; RAT; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; EVOLUTION, MOLECULAR; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RATS; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT;

EID: 15544373780     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb888     Document Type: Article

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