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Volumn 137, Issue 8, 2002, Pages 1163-1172

Molecular pharmacology of the human prostaglandin D 2 receptor, CRTH2

Author keywords

Binding assay; CRTH2; DP; Eosinophils; Intracellular signalling; Pharmacology; Prostaglandin D 2; Prostanoid receptor; Recombinant; Tissue distribution

Indexed keywords

13,14 DIHYDRO 15 OXOPROSTAGLANDIN D2; 15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 15 METHYLPROSTAGLANDIN D2; CYCLIC AMP; DELTA12 PROSTAGLANDIN J2; GUANINE NUCLEOTIDE BINDING PROTEIN; ILOPROST; MESSENGER RNA; PERTUSSIS TOXIN; PROSTAGLANDIN D2; PROSTAGLANDIN D2 RECEPTOR CRTH2; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN J2; PROSTAGLANDIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 0036944934     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704973     Document Type: Article
Times cited : (184)

References (26)
  • 3
    • 0029134144 scopus 로고
    • Molecular cloning and characterization of the human prostanoid DP receptor
    • Boie, Y., Sawyer, N., Slipetz, D.M., Metters, K.M. & Abramovitz, M. (1995). Molecular cloning and characterization of the human prostanoid DP receptor. J. Biol. Chem., 270, 18910-18916.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18910-18916
    • Boie, Y.1    Sawyer, N.2    Slipetz, D.M.3    Metters, K.M.4    Abramovitz, M.5
  • 4
    • 0028183018 scopus 로고
    • International Union of Pharmacology classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes
    • Coleman, R.A., Smith, W.L. & Narumiya, S. (1994). International Union of Pharmacology classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes. Pharmacol. Rev., 46, 205-229.
    • (1994) Pharmacol. Rev. , vol.46 , pp. 205-229
    • Coleman, R.A.1    Smith, W.L.2    Narumiya, S.3
  • 6
    • 0036467528 scopus 로고    scopus 로고
    • 15-Deoxy-Delta(12,14)(12,14)-PGJ(2) induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway
    • Harris, S.G., Smith, R.S. & Phipps, R.P. (2002). 15-Deoxy-Delta(12,14)(12,14)-PGJ(2) induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway. J. Immunol., 168, 1372-1379.
    • (2002) J. Immunol. , vol.168 , pp. 1372-1379
    • Harris, S.G.1    Smith, R.S.2    Phipps, R.P.3
  • 7
    • 0036467346 scopus 로고    scopus 로고
    • Cutting edge: Agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2
    • Hirai, H., Tanaka, K., Takano, S., Ichimasa, M., Nakamura, M. & Nagata, K. (2002). Cutting edge: Agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2. J. Immunol., 168, 981-985.
    • (2002) J. Immunol. , vol.168 , pp. 981-985
    • Hirai, H.1    Tanaka, K.2    Takano, S.3    Ichimasa, M.4    Nakamura, M.5    Nagata, K.6
  • 8
    • 0035862329 scopus 로고    scopus 로고
    • Prostaglandin D2 selectively induces chemotaxis in T Helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2
    • Hirai, H., Tanaka, K., Yoshie, O., Ogawa, K., Kenmotsu, K., Takamori, Y., Ichimasa, M., Sugamura, K.M.N., Takano, S. & Nagata, K. (2001). Prostaglandin D2 selectively induces chemotaxis in T Helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. J. Exp. Med., 193, 255-261.
    • (2001) J. Exp. Med. , vol.193 , pp. 255-261
    • Hirai, H.1    Tanaka, K.2    Yoshie, O.3    Ogawa, K.4    Kenmotsu, K.5    Takamori, Y.6    Ichimasa, M.7    Sugamura, K.M.N.8    Takano, S.9    Nagata, K.10
  • 11
    • 0035883174 scopus 로고    scopus 로고
    • Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor
    • Monneret, G., Gravel, S., Diamond, M., Rokach, J. & Powell, W.S. (2001). Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor. Blood, 98, 1942-1948.
    • (2001) Blood , vol.98 , pp. 1942-1948
    • Monneret, G.1    Gravel, S.2    Diamond, M.3    Rokach, J.4    Powell, W.S.5
  • 13
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: Structures, properties, and functions
    • Narumiya, S., Sugimoto, Y. & Ushikubi, F. (1999). Prostanoid receptors: Structures, properties, and functions. Physiol. Rev., 79, 1193-1226.
    • (1999) Physiol. Rev. , vol.79 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 14
    • 0028981057 scopus 로고
    • G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C
    • Offermanns, S. & Simon, M.I. (1995). G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C. J. Biol. Chem., 270, 15175-15180.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15175-15180
    • Offermanns, S.1    Simon, M.I.2
  • 15
    • 0028834452 scopus 로고
    • Changing the differentiation program of hematopoietic cells: Retinoic acid-induced shift of eosinophil-committed cells to neutrophils
    • Paul, C.C., Mahrer, S., Tolbert, M., Elbert, B.L., Wong, I., Ackerman, S.J. & Baumann, M.A. (1995). Changing the differentiation program of hematopoietic cells: Retinoic acid-induced shift of eosinophil-committed cells to neutrophils. Blood, 86, 3737-3744.
    • (1995) Blood , vol.86 , pp. 3737-3744
    • Paul, C.C.1    Mahrer, S.2    Tolbert, M.3    Elbert, B.L.4    Wong, I.5    Ackerman, S.J.6    Baumann, M.A.7
  • 16
    • 0029610569 scopus 로고
    • Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: An argument for a different DP receptor?
    • Rangachari, P.K., Betti, P.A., Prior, E.T. & Roberts, L.J. (1995). Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: An argument for a different DP receptor? J. Pharmacol. Exp. Ther., 275, 611-617.
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 611-617
    • Rangachari, P.K.1    Betti, P.A.2    Prior, E.T.3    Roberts, L.J.4
  • 17
    • 0017904089 scopus 로고
    • Prostaglandin D2 (PGD2) a potent coronary vasoconstrictor agent in the guinea pig isolated heart
    • Schror, K. (1978). Prostaglandin D2 (PGD2) a potent coronary vasoconstrictor agent in the guinea pig isolated heart. Naunyn Schmiedebergs Arch. Pharmacol., 302, 61-62.
    • (1978) Naunyn Schmiedebergs Arch. Pharmacol. , vol.302 , pp. 61-62
    • Schror, K.1
  • 18
    • 0030014459 scopus 로고    scopus 로고
    • Regulation of leukotriene-biosynthetic enzymes during differentiation of myelocytic HL-60 cells to eosinophilic or neutrophilic cells
    • Scoggan, K.A., Nicholson, D.W. & Ford-Hutchinson, A.W. (1996). Regulation of leukotriene-biosynthetic enzymes during differentiation of myelocytic HL-60 cells to eosinophilic or neutrophilic cells. Eur. J. Biochem., 239, 572-578.
    • (1996) Eur. J. Biochem. , vol.239 , pp. 572-578
    • Scoggan, K.A.1    Nicholson, D.W.2    Ford-Hutchinson, A.W.3
  • 19
    • 0017636029 scopus 로고
    • Chemical and biological studies on indomethacin, sulindac and their analogs
    • Simons, A.B., ed. New York: Academic
    • Shen, T.Y. & Winter, C.A. (1977). Chemical and biological studies on indomethacin, sulindac and their analogs. In Advances in Drug Research. Simons, A.B., ed. p.89. New York: Academic.
    • (1977) Advances in Drug Research , pp. 89
    • Shen, T.Y.1    Winter, C.A.2
  • 20
    • 0012481804 scopus 로고    scopus 로고
    • 15-Deoxy-delta12,14-prostaglandin J2: A prostaglandin D2 metabolite generated during inflammatory processes
    • Shibata, T., Kondo, M., Osawa, T., Shibata, N., Kobayashi, M. & Uchida, K. (2002). 15-Deoxy-delta12,14-prostaglandin J2: A prostaglandin D2 metabolite generated during inflammatory processes. J. Biol. Chem., 10, 10.
    • (2002) J. Biol. Chem. , vol.10 , pp. 10
    • Shibata, T.1    Kondo, M.2    Osawa, T.3    Shibata, N.4    Kobayashi, M.5    Uchida, K.6
  • 21
    • 0027214868 scopus 로고
    • Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C beta by G protein alpha and beta gamma subunits
    • Smrcka, A.V. & Sternweis, P.C. (1993). Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C beta by G protein alpha and beta gamma subunits. J. Biol. Chem., 268, 9667-9674.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9667-9674
    • Smrcka, A.V.1    Sternweis, P.C.2
  • 22
    • 0035053973 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins: New insights on biological activities and cellular targets
    • Straus, D.S. & Glass, C.K. (2001). Cyclopentenone prostaglandins: New insights on biological activities and cellular targets. Med. Res. Rev., 21, 185-210.
    • (2001) Med. Res. Rev. , vol.21 , pp. 185-210
    • Straus, D.S.1    Glass, C.K.2
  • 24
    • 0031913845 scopus 로고    scopus 로고
    • Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist
    • Wright, D.H., Metters, K.M., Abramovitz, M. & Ford-Hutchinson, A.W. (1998). Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist. Br. J. Pharmacol., 123, 1317-1324.
    • (1998) Br. J. Pharmacol. , vol.123 , pp. 1317-1324
    • Wright, D.H.1    Metters, K.M.2    Abramovitz, M.3    Ford-Hutchinson, A.W.4
  • 25
    • 0033031591 scopus 로고    scopus 로고
    • A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor
    • Wright, D.H., Nantel, F., Metters, K.M. & Ford-Hutchinson, A.W. (1999). A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor. Eur. J. Pharmacol., 377, 101-115.
    • (1999) Eur. J. Pharmacol. , vol.377 , pp. 101-115
    • Wright, D.H.1    Nantel, F.2    Metters, K.M.3    Ford-Hutchinson, A.W.4
  • 26
    • 0029863008 scopus 로고    scopus 로고
    • G protein subunits and the stimulation of phosphlipase C by Gs- and Gi-coupled receptors: Lack of receptor selectivity of Galpha(16) and evidence for a synergic interaction between Gbeta gamma and the alpha subunit of a receptor activated G protein
    • Zhu, X. & Birnbaumer, L. (1996). G protein subunits and the stimulation of phosphlipase C by Gs- and Gi-coupled receptors: Lack of receptor selectivity of Galpha(16) and evidence for a synergic interaction between Gbeta gamma and the alpha subunit of a receptor activated G protein. Proc. Natl. Acad. Sci. U.S.A., 93, 2827-2831.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 2827-2831
    • Zhu, X.1    Birnbaumer, L.2


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