-
1
-
-
0031815337
-
Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: Evidence for agonist-directed trafficking of receptor stimulus
-
Berg KA, Maayani S, Goldfarb J, Scaramellini C, Leff P, and Clarke WP (1998) Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus. Mol Pharmacol 54:94-104.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 94-104
-
-
Berg, K.A.1
Maayani, S.2
Goldfarb, J.3
Scaramellini, C.4
Leff, P.5
Clarke, W.P.6
-
2
-
-
0030826705
-
A selective inverse agonist for central cannabinoid receptor inhibits mitogen-activated protein kinase activation stimulated by insulin or insulin-like growth factor 1. Evidence for a new model of receptor/ligand interactions
-
Bouaboula M, Perrachon S, Milligan L, Canat X, Rinaldi-Carmona M, Portier M, Barth F, Calandra B, Pecceu F, Lupker J, et al. (1997) A selective inverse agonist for central cannabinoid receptor inhibits mitogen-activated protein kinase activation stimulated by insulin or insulin-like growth factor 1. Evidence for a new model of receptor/ligand interactions. J Biol Chem 272:22330-22339.
-
(1997)
J Biol Chem
, vol.272
, pp. 22330-22339
-
-
Bouaboula, M.1
Perrachon, S.2
Milligan, L.3
Canat, X.4
Rinaldi-Carmona, M.5
Portier, M.6
Barth, F.7
Calandra, B.8
Pecceu, F.9
Lupker, J.10
-
3
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
5
-
-
0027469601
-
Affinity purification of a somatostatin receptor-G-protein complex demonstrates specificity in receptor-G-protein coupling
-
Brown PJ and Schonbrunn A (1993) Affinity purification of a somatostatin receptor-G-protein complex demonstrates specificity in receptor-G-protein coupling. J Biol Chem 268:6668-6676.
-
(1993)
J Biol Chem
, vol.268
, pp. 6668-6676
-
-
Brown, P.J.1
Schonbrunn, A.2
-
6
-
-
0035448297
-
Independent and synergistic interaction of retinal G-protein subunits with bovine rhodopsin measured by surface plasmon resonance
-
Clark WA, Jian X, Chen L, and Northup JK (2001) Independent and synergistic interaction of retinal G-protein subunits with bovine rhodopsin measured by surface plasmon resonance. Biochem J 358:389-397.
-
(2001)
Biochem J
, vol.358
, pp. 389-397
-
-
Clark, W.A.1
Jian, X.2
Chen, L.3
Northup, J.K.4
-
7
-
-
0032127619
-
The elusive nature of intrinsic efficacy
-
Clarke WP and Bond RA (1998) The elusive nature of intrinsic efficacy. Trends Pharmacol Sci 19:270-276.
-
(1998)
Trends Pharmacol Sci
, vol.19
, pp. 270-276
-
-
Clarke, W.P.1
Bond, R.A.2
-
9
-
-
0033572358
-
The G protein subunit gene families
-
Downes GB and Gautam N (1999) The G protein subunit gene families. Genomics 62:544-552.
-
(1999)
Genomics
, vol.62
, pp. 544-552
-
-
Downes, G.B.1
Gautam, N.2
-
10
-
-
0034914658
-
Suppression of cellular invasion by activated G-protein subunits Gαo, Gαi1, Gαi2 and Gαi3 and sequestration of Gβγ
-
Faivre S, Regnauld K, Bruyneel E, Nguyen QD, Mareel M, Emami S, and Gespach C (2001) Suppression of cellular invasion by activated G-protein subunits Gαo, Gαi1, Gαi2 and Gαi3 and sequestration of Gβγ. Mol Pharmacol 60:363-372.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 363-372
-
-
Faivre, S.1
Regnauld, K.2
Bruyneel, E.3
Nguyen, Q.D.4
Mareel, M.5
Emami, S.6
Gespach, C.7
-
11
-
-
0031018485
-
Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility
-
Gether U, Ballesteros JA, Seifert R, Sanders-Bush E, Weinstein H, and Kobilka BK (1997) Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility. J Biol Chem 272:2587-2590.
-
(1997)
J Biol Chem
, vol.272
, pp. 2587-2590
-
-
Gether, U.1
Ballesteros, J.A.2
Seifert, R.3
Sanders-Bush, E.4
Weinstein, H.5
Kobilka, B.K.6
-
14
-
-
0026511046
-
Subunit interactions of GTP-binding proteins
-
Heithier H, Frohlich M, Dees C, Baumann M, Haring M, Gierschik P, Schiltz E, Vaz WL, Hekman M, and Helmreich EJ (1992) Subunit interactions of GTP-binding proteins. Eur J Biochem 204:1169-1181.
-
(1992)
Eur J Biochem
, vol.204
, pp. 1169-1181
-
-
Heithier, H.1
Frohlich, M.2
Dees, C.3
Baumann, M.4
Haring, M.5
Gierschik, P.6
Schiltz, E.7
Vaz, W.L.8
Hekman, M.9
Helmreich, E.J.10
-
15
-
-
0027396592
-
Solubilization of the Cannabinoid receptor from rat brain and its functional interaction with guanine nucleotide-binding proteins
-
Houston DB and Howlett AC (1993) Solubilization of the Cannabinoid receptor from rat brain and its functional interaction with guanine nucleotide-binding proteins. Mol Pharmacol 43:17-22.
-
(1993)
Mol Pharmacol
, vol.43
, pp. 17-22
-
-
Houston, D.B.1
Howlett, A.C.2
-
16
-
-
0031697763
-
Differential receptor-G-protein coupling evoked by dissimilar cannabinoid receptor agonists
-
Houston DB and Howlett AC (1998) Differential receptor-G-protein coupling evoked by dissimilar cannabinoid receptor agonists. Cell Signal 10:667-674.
-
(1998)
Cell Signal
, vol.10
, pp. 667-674
-
-
Houston, D.B.1
Howlett, A.C.2
-
17
-
-
18444376760
-
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
-
Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, et al. (2002) International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 54:161-202.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
-
19
-
-
0031594615
-
Characterization of CB1 cannabinoid receptors using receptor peptide fragments and site-directed antibodies
-
Howlett AC, Song C, Berglund BA, Wilken GH, and Pigg JJ (1998) Characterization of CB1 cannabinoid receptors using receptor peptide fragments and site-directed antibodies. Mol Pharmacol 53:504-510.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 504-510
-
-
Howlett, A.C.1
Song, C.2
Berglund, B.A.3
Wilken, G.H.4
Pigg, J.J.5
-
20
-
-
0029054965
-
Agonist-receptor efficacy. II. Agonist trafficking of receptor signals
-
Kenakin T (1995) Agonist-receptor efficacy. II. Agonist trafficking of receptor signals. Trends Pharmacol Sci 16:232-238.
-
(1995)
Trends Pharmacol Sci
, vol.16
, pp. 232-238
-
-
Kenakin, T.1
-
21
-
-
0036591660
-
The ligand paradox between affinity and efficacy: Can you be there and not make a difference?
-
Kenakin T and Onaran O (2002) The ligand paradox between affinity and efficacy: can you be there and not make a difference? Trends Pharmacol Sci 23:275-280.
-
(2002)
Trends Pharmacol Sci
, vol.23
, pp. 275-280
-
-
Kenakin, T.1
Onaran, O.2
-
22
-
-
0032959367
-
Stable association of G proteins with beta 2AR is independent of the state of receptor activation
-
Lachance M, Ethier N, Wolbring G, Schnetkamp PP, and Hebert TE (1999) Stable association of G proteins with beta 2AR is independent of the state of receptor activation. Cell Signal 11:523-533.
-
(1999)
Cell Signal
, vol.11
, pp. 523-533
-
-
Lachance, M.1
Ethier, N.2
Wolbring, G.3
Schnetkamp, P.P.4
Hebert, T.E.5
-
23
-
-
0027092070
-
Agonist binding to rat brain somatostatin receptors alters the interaction of the receptors with guanine nucleotide-binding regulatory proteins
-
Law SF and Reisine T (1992) Agonist binding to rat brain somatostatin receptors alters the interaction of the receptors with guanine nucleotide-binding regulatory proteins. Mol Pharmacol 42:398-402.
-
(1992)
Mol Pharmacol
, vol.42
, pp. 398-402
-
-
Law, S.F.1
Reisine, T.2
-
24
-
-
0030985952
-
Changes in the association of G protein subunits with the cloned mouse δ opioid receptor on agonist stimulation
-
Law SF and Reisine T (1997) Changes in the association of G protein subunits with the cloned mouse δ opioid receptor on agonist stimulation. J Pharmacol Exp Ther 281:1476-1486.
-
(1997)
J Pharmacol Exp Ther
, vol.281
, pp. 1476-1486
-
-
Law, S.F.1
Reisine, T.2
-
27
-
-
0034741597
-
CB1 receptor-G protein association. Subtype selectivity is determined by distinct intracellular domains
-
Mukhopadhyay S and Howlett AC (2001) CB1 receptor-G protein association. Subtype selectivity is determined by distinct intracellular domains. Eur J Biochem 268:499-505.
-
(2001)
Eur J Biochem
, vol.268
, pp. 499-505
-
-
Mukhopadhyay, S.1
Howlett, A.C.2
-
30
-
-
0023481358
-
Site-directed immobilization of glycoproteins on hydrazide-containing solid supports
-
O'Shannessy DJ and Hoffman WL (1987) Site-directed immobilization of glycoproteins on hydrazide-containing solid supports. Biotechnol Appl Biochem 9:488-496.
-
(1987)
Biotechnol Appl Biochem
, vol.9
, pp. 488-496
-
-
O'Shannessy, D.J.1
Hoffman, W.L.2
-
31
-
-
0032407482
-
2+ currents by reversal of tonic CB1 cannabinoid receptor activity
-
2+ currents by reversal of tonic CB1 cannabinoid receptor activity. Mol Pharmacol 54:1064-1072.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 1064-1072
-
-
Pan, X.1
Ikeda, S.R.2
Lewis, D.L.3
-
32
-
-
0030049488
-
Constitutive activation of a single effector pathway: Evidence for multiple activation states of a G protein-coupled receptor
-
Perez DM, Hwa J, Gaivin R, Mathur M, Brown F, and Graham RM (1996) Constitutive activation of a single effector pathway: evidence for multiple activation states of a G protein-coupled receptor. Mol Pharmacol 49:112-122.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 112-122
-
-
Perez, D.M.1
Hwa, J.2
Gaivin, R.3
Mathur, M.4
Brown, F.5
Graham, R.M.6
-
33
-
-
0034056416
-
Activation of cannabinoid receptors in rat brain by WIN 55212-2 produces coupling to multiple G protein α-subunits with different potencies
-
Prather PL, Martin NA, Breivogel CS, and Childers SR (2000) Activation of cannabinoid receptors in rat brain by WIN 55212-2 produces coupling to multiple G protein α-subunits with different potencies. Mol Pharmacol 57:1000-1010.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 1000-1010
-
-
Prather, P.L.1
Martin, N.A.2
Breivogel, C.S.3
Childers, S.R.4
-
34
-
-
0035794019
-
Inhibitory effects of SR141716A on G-protein activation in rat brain
-
Sim-Selley LJ, Brunk LK, and Selley DE (2001) Inhibitory effects of SR141716A on G-protein activation in rat brain. Eur J Pharmacol 414:135-143.
-
(2001)
Eur J Pharmacol
, vol.414
, pp. 135-143
-
-
Sim-Selley, L.J.1
Brunk, L.K.2
Selley, D.E.3
-
35
-
-
0041341923
-
Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: A molecular basis for agonist-directed trafficking of receptor stimulus
-
Skrzydelski D, Lhiaubet AM, Lebeau A, Forgez P, Yamada M, Hermans E, Rostene W, and Pelaprat D (2003) Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: a molecular basis for agonist-directed trafficking of receptor stimulus. Mol Pharmacol 64:421-429.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 421-429
-
-
Skrzydelski, D.1
Lhiaubet, A.M.2
Lebeau, A.3
Forgez, P.4
Yamada, M.5
Hermans, E.6
Rostene, W.7
Pelaprat, D.8
-
36
-
-
0342979873
-
The CB1 cannabinoid receptor can sequester G-proteins, making them unavailable to couple to other receptors
-
Vasquez C and Lewis DL (1999) The CB1 cannabinoid receptor can sequester G-proteins, making them unavailable to couple to other receptors. J Neurosci 19:9271-9280.
-
(1999)
J Neurosci
, vol.19
, pp. 9271-9280
-
-
Vasquez, C.1
Lewis, D.L.2
-
37
-
-
0033429099
-
Kinetics versus equilibrium: The importance of GTP in GPCR activation
-
Waelbroeck I (1999) Kinetics versus equilibrium: the importance of GTP in GPCR activation. Trends Pharmacol Sci 20:477-481.
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 477-481
-
-
Waelbroeck, I.1
-
38
-
-
0037195456
-
Signaling through Gi family members in platelets. Redundancy and specificity in the regulation of adenylyl cyclase and other effectors
-
Yang J, Wu J, Jiang H, Mortensen R, Austin S, Manning DR, Woulfe D, and Brass LF (2002) Signaling through Gi family members in platelets. Redundancy and specificity in the regulation of adenylyl cyclase and other effectors. J Biol Chem 277:46035-46042.
-
(2002)
J Biol Chem
, vol.277
, pp. 46035-46042
-
-
Yang, J.1
Wu, J.2
Jiang, H.3
Mortensen, R.4
Austin, S.5
Manning, D.R.6
Woulfe, D.7
Brass, L.F.8
-
39
-
-
0032819108
-
Influence of G protein type on agonist efficacy
-
Yang Q and Lanier SM (1999) Influence of G protein type on agonist efficacy. Mol Pharmacol 56:651-656.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 651-656
-
-
Yang, Q.1
Lanier, S.M.2
|