메뉴 건너뛰기




Volumn 25, Issue 6, 2004, Pages 725-733

Alzheimer's disease - A sum greater than its parts?

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

EID: 2542625173     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2003.12.016     Document Type: Note
Times cited : (21)

References (128)
  • 1
    • 0036946621 scopus 로고    scopus 로고
    • Morphologically distinct plaque types differentially affect dendritic structure and organisation in the early and late stages of Alzheimer's disease
    • Adlard P., Vickers J. Morphologically distinct plaque types differentially affect dendritic structure and organisation in the early and late stages of Alzheimer's disease. Acta Neuropathol (Berl). 103:2002;377-383
    • (2002) Acta Neuropathol (Berl) , vol.103 , pp. 377-383
    • Adlard, P.1    Vickers, J.2
  • 2
    • 0035851157 scopus 로고    scopus 로고
    • Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein
    • Alonso A., Zaidi T., Novak M., Barra H., Grundke-Iqbal I., Iqbal K. Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein. J Biol Chem. 276:2001;37967-37973
    • (2001) J Biol Chem , vol.276 , pp. 37967-37973
    • Alonso, A.1    Zaidi, T.2    Novak, M.3    Barra, H.4    Grundke-Iqbal, I.5    Iqbal, K.6
  • 3
    • 0035997249 scopus 로고    scopus 로고
    • Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins
    • Atwood C., Martins R., Smith M., Perry G. Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides. 23:2002;1343-1350
    • (2002) Peptides , vol.23 , pp. 1343-1350
    • Atwood, C.1    Martins, R.2    Smith, M.3    Perry, G.4
  • 4
    • 0036937699 scopus 로고    scopus 로고
    • Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
    • Augustinack J., Schneider A., Mandelkow E., Hyman B. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. Acta Neuropathol (Berl). 103:2002;26-35
    • (2002) Acta Neuropathol (Berl) , vol.103 , pp. 26-35
    • Augustinack, J.1    Schneider, A.2    Mandelkow, E.3    Hyman, B.4
  • 5
    • 0002270783 scopus 로고
    • Diagnosis
    • Terry R, Katzman R, Bick K, editors. New York: Raven Press;
    • Berg L, Morris J. Diagnosis. In: Terry R, Katzman R, Bick K, editors. Alzheimer disease. New York: Raven Press; 1994. p. 9-25.
    • (1994) Alzheimer Disease , pp. 9-25
    • Berg, L.1    Morris, J.2
  • 6
    • 0014313861 scopus 로고
    • The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects
    • Blessed G., Tomlinson B., Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry. 114:1968;797-811
    • (1968) Br J Psychiatry , vol.114 , pp. 797-811
    • Blessed, G.1    Tomlinson, B.2    Roth, M.3
  • 7
    • 0030833055 scopus 로고    scopus 로고
    • Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
    • Borchelt D., Ratovitski T., van Lare J., Lee M., Gonzales V., Jenkins N., et al. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron. 19:1997;939-945
    • (1997) Neuron , vol.19 , pp. 939-945
    • Borchelt, D.1    Ratovitski, T.2    Van Lare, J.3    Lee, M.4    Gonzales, V.5    Jenkins, N.6
  • 8
    • 0034911946 scopus 로고    scopus 로고
    • Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype
    • Brat D., Gearing M., Goldthwaite P., Wainer B., Burger P. Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype. Neuropathol Appl Neurobiol. 27:2001;197-205
    • (2001) Neuropathol Appl Neurobiol , vol.27 , pp. 197-205
    • Brat, D.1    Gearing, M.2    Goldthwaite, P.3    Wainer, B.4    Burger, P.5
  • 9
    • 0031711244 scopus 로고    scopus 로고
    • Neurofibrillary tangles and Alzheimer's disease
    • Brion J. Neurofibrillary tangles and Alzheimer's disease. Eur Neurol. 40:1998;130-140
    • (1998) Eur Neurol , vol.40 , pp. 130-140
    • Brion, J.1
  • 10
    • 0037041420 scopus 로고    scopus 로고
    • Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
    • Bucciantini M., Giannoni E., Chiti F., Baroni F., Formigli L., Zurdo J., et al. Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature. 416:2002;507-511
    • (2002) Nature , vol.416 , pp. 507-511
    • Bucciantini, M.1    Giannoni, E.2    Chiti, F.3    Baroni, F.4    Formigli, L.5    Zurdo, J.6
  • 11
    • 0037067074 scopus 로고    scopus 로고
    • Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer's disease
    • Bussiere T., Friend P., Sadeghi N., Wicinski B., Lin G., Bouras C., et al. Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer's disease. Neuroscience. 112:2002;75-91
    • (2002) Neuroscience , vol.112 , pp. 75-91
    • Bussiere, T.1    Friend, P.2    Sadeghi, N.3    Wicinski, B.4    Lin, G.5    Bouras, C.6
  • 12
    • 0027526419 scopus 로고
    • Release of excess amyloid beta protein from a mutant amyloid beta protein precursor
    • Cai X., Golde T., Younkin S. Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science. 259:1993;514-516
    • (1993) Science , vol.259 , pp. 514-516
    • Cai, X.1    Golde, T.2    Younkin, S.3
  • 13
    • 0037474287 scopus 로고    scopus 로고
    • Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein
    • Cai D.M., Leem J., Greenfield J., Wang P., Kim B., Wang R., et al. Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein. J Biol Chem. 278:2003;3446-3454
    • (2003) J Biol Chem , vol.278 , pp. 3446-3454
    • Cai, D.M.1    Leem, J.2    Greenfield, J.3    Wang, P.4    Kim, B.5    Wang, R.6
  • 16
    • 0026075602 scopus 로고
    • Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene
    • Chartier-Harlin M., Crawford F., Houlden H., Warren A., Hughes D., Fidani L., et al. Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene. Nature. 353:1991;844-846
    • (1991) Nature , vol.353 , pp. 844-846
    • Chartier-Harlin, M.1    Crawford, F.2    Houlden, H.3    Warren, A.4    Hughes, D.5    Fidani, L.6
  • 17
    • 0026745610 scopus 로고
    • Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production
    • Citron M., Oltersdorf T., Haass C., McConlogue L., Hung A., Seubert R., et al. Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production. Nature. 360:1992;672-674
    • (1992) Nature , vol.360 , pp. 672-674
    • Citron, M.1    Oltersdorf, T.2    Haass, C.3    McConlogue, L.4    Hung, A.5    Seubert, R.6
  • 18
    • 0028099612 scopus 로고
    • Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation
    • Citron M., Vigo-Pelfrey C., Teplow D., Miller C., Schenk D., Johnston J., et al. Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation. Proc Natl Acad Sci USA. 91:1994;11993-11997
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11993-11997
    • Citron, M.1    Vigo-Pelfrey, C.2    Teplow, D.3    Miller, C.4    Schenk, D.5    Johnston, J.6
  • 20
    • 0030874738 scopus 로고    scopus 로고
    • Plaques and tangles: Searching for primary events in a forest of data
    • Cummings B.J. Plaques and tangles: searching for primary events in a forest of data. Neurobiol Aging. 18:1997;358-362
    • (1997) Neurobiol Aging , vol.18 , pp. 358-362
    • Cummings, B.J.1
  • 21
    • 0030464914 scopus 로고    scopus 로고
    • Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease
    • Cummings B.J., Pike C.J., Shankle R., Cotman C.W. Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease. Neurobiol Aging. 17:1996;921-933
    • (1996) Neurobiol Aging , vol.17 , pp. 921-933
    • Cummings, B.J.1    Pike, C.J.2    Shankle, R.3    Cotman, C.W.4
  • 22
    • 0029835167 scopus 로고    scopus 로고
    • Diffuse plaques contain C-terminal Aβ42 and not Aβ40: Evidence from cats and dogs
    • Cummings B.J., Satou T., Head E., Milgram N.W., Cole G.M., Savage M.J., et al. Diffuse plaques contain C-terminal Aβ42 and not Aβ40: evidence from cats and dogs. Neurobiol Aging. 17:1996;653-659
    • (1996) Neurobiol Aging , vol.17 , pp. 653-659
    • Cummings, B.J.1    Satou, T.2    Head, E.3    Milgram, N.W.4    Cole, G.M.5    Savage, M.J.6
  • 23
    • 0026718402 scopus 로고
    • Aggregation of the amyloid precursor protein (APP) within degenerating neurons and dystrophic neurites in Alzheimer's Disease
    • Cummings B.J., Su J.H., Geddes J.W., Van Nostrand W., Wagner S., Cunningham D., et al. Aggregation of the amyloid precursor protein (APP) within degenerating neurons and dystrophic neurites in Alzheimer's Disease. Neuroscience. 48:1992;763-777
    • (1992) Neuroscience , vol.48 , pp. 763-777
    • Cummings, B.J.1    Su, J.H.2    Geddes, J.W.3    Van Nostrand, W.4    Wagner, S.5    Cunningham, D.6
  • 24
    • 22444451794 scopus 로고    scopus 로고
    • Sequential neurofibrillary degeneration in aging and Alzheimer's disease: New clues for therapy
    • Delacourte A. Sequential neurofibrillary degeneration in aging and Alzheimer's disease: new clues for therapy. Alzheimer's Rep. 1(Suppl 1):1998;31-32
    • (1998) Alzheimer's Rep , vol.1 , Issue.SUPPL. 1 , pp. 31-32
    • Delacourte, A.1
  • 25
    • 0037072278 scopus 로고    scopus 로고
    • Nonoverlapping but synergistic tau and APP pathologies in sporadic Alzheimer's disease
    • Delacourte A., Sergeant N., Champain D., Wattez A., Maurage C., Lebert F., et al. Nonoverlapping but synergistic tau and APP pathologies in sporadic Alzheimer's disease. Neurology. 59:2002;398-407
    • (2002) Neurology , vol.59 , pp. 398-407
    • Delacourte, A.1    Sergeant, N.2    Champain, D.3    Wattez, A.4    Maurage, C.5    Lebert, F.6
  • 26
    • 0033066239 scopus 로고    scopus 로고
    • Neurochemical diversity of dystrophic neurites in the early and late stages of Alzheimer's disease
    • Dickson T., King C., McCormack G., Vickers J. Neurochemical diversity of dystrophic neurites in the early and late stages of Alzheimer's disease. Exp Neurol. 1:1999;100-110
    • (1999) Exp Neurol , vol.1 , pp. 100-110
    • Dickson, T.1    King, C.2    McCormack, G.3    Vickers, J.4
  • 27
    • 16044366039 scopus 로고    scopus 로고
    • Increased amyloid-β 1-42(43) in the brains of mice expressing mutant presenilin 1
    • Duff K., Eckman C., Zehr C., Yu X., Prada C., Perez-tur J., et al. Increased amyloid-β 1-42(43) in the brains of mice expressing mutant presenilin 1. Nature. 383:1996;710-713
    • (1996) Nature , vol.383 , pp. 710-713
    • Duff, K.1    Eckman, C.2    Zehr, C.3    Yu, X.4    Prada, C.5    Perez-Tur, J.6
  • 28
    • 0030977392 scopus 로고    scopus 로고
    • Frontotemporal dementia and Parkinsonism linked to chromosome 17: A consensus conference. Conference Participants
    • Foster N., Wilhelmsen K., Sima A., Jones M., D'Amato C., Gilman S. Frontotemporal dementia and Parkinsonism linked to chromosome 17: a consensus conference. Conference Participants. Ann Neurol. 41:1997;706-715
    • (1997) Ann Neurol , vol.41 , pp. 706-715
    • Foster, N.1    Wilhelmsen, K.2    Sima, A.3    Jones, M.4    D'Amato, C.5    Gilman, S.6
  • 29
    • 0028985574 scopus 로고
    • Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
    • Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature. 373:1995;523-527
    • (1995) Nature , vol.373 , pp. 523-527
    • Games, D.1    Adams, D.2    Alessandrini, R.3    Barbour, R.4    Berthelette, P.5    Blackwell, C.6
  • 30
    • 0026757897 scopus 로고
    • Lack of Alzheimer pathology after β-amyloid protein injections in rat brain
    • Games D., Khan K., Soriano F., Kein P., Davis D., Bryant K., et al. Lack of Alzheimer pathology after β-amyloid protein injections in rat brain. Neurobiol Aging. 13:1992;569-576
    • (1992) Neurobiol Aging , vol.13 , pp. 569-576
    • Games, D.1    Khan, K.2    Soriano, F.3    Kein, P.4    Davis, D.5    Bryant, K.6
  • 33
    • 0024496624 scopus 로고
    • Down patients: Extracellular preamyloid deposits precede neuritic degeneration and senile plaques
    • Giaccone G., Tagliavini F., Linoli G., Bouras C., Frigerio L., Frangione B., et al. Down patients: extracellular preamyloid deposits precede neuritic degeneration and senile plaques. Neurosci Lett. 97:1989;232-238
    • (1989) Neurosci Lett , vol.97 , pp. 232-238
    • Giaccone, G.1    Tagliavini, F.2    Linoli, G.3    Bouras, C.4    Frigerio, L.5    Frangione, B.6
  • 34
    • 0026088977 scopus 로고
    • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
    • Goate A., Chartier-Harlin M., Mullan M., Brown J., Crawford F., Fidani L., et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature. 349:1991;704-706
    • (1991) Nature , vol.349 , pp. 704-706
    • Goate, A.1    Chartier-Harlin, M.2    Mullan, M.3    Brown, J.4    Crawford, F.5    Fidani, L.6
  • 35
    • 0032214501 scopus 로고    scopus 로고
    • Tau mutations cause frontotemporal dementias
    • Goedert M., Crowther R., Spillantini M. Tau mutations cause frontotemporal dementias. Neuron. 21:1998;955-958
    • (1998) Neuron , vol.21 , pp. 955-958
    • Goedert, M.1    Crowther, R.2    Spillantini, M.3
  • 36
    • 0022497166 scopus 로고
    • Spongiform encephalopathy: A neurocytologists viewpoint with a note on Alzheimer's disease
    • Gray E. Spongiform encephalopathy: a neurocytologists viewpoint with a note on Alzheimer's disease. Neuropathol Appl Neurobiol. 12:1986;149-172
    • (1986) Neuropathol Appl Neurobiol , vol.12 , pp. 149-172
    • Gray, E.1
  • 37
    • 0023187131 scopus 로고
    • Alzheimer's disease: Paired helical filaments and cytomembranes
    • Gray E., Paula-Barbosa M., Roher A. Alzheimer's disease: paired helical filaments and cytomembranes. J Neuropathol Appl Neurobiol. 13:1987;91-110
    • (1987) J Neuropathol Appl Neurobiol , vol.13 , pp. 91-110
    • Gray, E.1    Paula-Barbosa, M.2    Roher, A.3
  • 38
    • 0033615580 scopus 로고    scopus 로고
    • The presenilins in Alzheimer's disease - Proteolysis holds the key
    • Haass C., De Strooper B. The presenilins in Alzheimer's disease - proteolysis holds the key. Science. 286:1999;916-919
    • (1999) Science , vol.286 , pp. 916-919
    • Haass, C.1    De Strooper, B.2
  • 39
    • 0031052381 scopus 로고    scopus 로고
    • Amyloid, the presenillins and Alzheimer's disease
    • Hardy J. Amyloid, the presenillins and Alzheimer's disease. Trends Neurosci. 20:1997;154-159
    • (1997) Trends Neurosci , vol.20 , pp. 154-159
    • Hardy, J.1
  • 40
    • 0038618836 scopus 로고    scopus 로고
    • The relationship between amyloid and tau
    • Hardy J. The relationship between amyloid and tau. J Mol Neurosci. 20:2003;203-206
    • (2003) J Mol Neurosci , vol.20 , pp. 203-206
    • Hardy, J.1
  • 41
    • 0025899041 scopus 로고
    • Amyloid deposition as the central event in the aetiology of Alzheimer's disease
    • Hardy J., Allsop D. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol Sci. 12:1991;383-388
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 383-388
    • Hardy, J.1    Allsop, D.2
  • 42
    • 0032150877 scopus 로고    scopus 로고
    • Genetic dissection of Alzheimer's disease and related dementias: Amyloid and its relationship to tau
    • Hardy J., Duff K., Hardy K., Perez-Tur J., Hutton M. Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau. Nat Neurosci. 1:1998;355-358
    • (1998) Nat Neurosci , vol.1 , pp. 355-358
    • Hardy, J.1    Duff, K.2    Hardy, K.3    Perez-Tur, J.4    Hutton, M.5
  • 43
    • 0033535470 scopus 로고    scopus 로고
    • In search of gamma-secretase
    • Hardy J., Israël A. In search of gamma-secretase. Nature. 398:1999;466-467
    • (1999) Nature , vol.398 , pp. 466-467
    • Hardy, J.1    Israël, A.2
  • 44
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J., Selkoe D. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 297:2002;353-356
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.2
  • 45
    • 0141814636 scopus 로고    scopus 로고
    • Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice
    • Harris F., Brecht W., Xu Q., Tesseur I., Kekonius L., Wyss-Coray T., et al. Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice. Proc Natl Acad Sci USA. 100:2003;10966-10971
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10966-10971
    • Harris, F.1    Brecht, W.2    Xu, Q.3    Tesseur, I.4    Kekonius, L.5    Wyss-Coray, T.6
  • 46
    • 0033570337 scopus 로고    scopus 로고
    • Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
    • Hartley D., Walsh D., Ye C., Diehl T., Vasquez S., Vassilev P., et al. Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J Neurosci. 19:1999;8876-8884
    • (1999) J Neurosci , vol.19 , pp. 8876-8884
    • Hartley, D.1    Walsh, D.2    Ye, C.3    Diehl, T.4    Vasquez, S.5    Vassilev, P.6
  • 47
    • 0026879650 scopus 로고
    • Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene
    • Hendriks L., van Duijn C., Cras P., Cruts M., Van Hul W., van Harskamp F., et al. Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene. Nat Genet. 1:1992;218-221
    • (1992) Nat Genet , vol.1 , pp. 218-221
    • Hendriks, L.1    Van Duijn, C.2    Cras, P.3    Cruts, M.4    Van Hul, W.5    Van Harskamp, F.6
  • 48
    • 0037444574 scopus 로고    scopus 로고
    • Gamma-secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation
    • Herreman A., Van Gassen G., Bentahir M., Nyabi O., Craessaerts K., Mueller U., et al. Gamma-secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation. J Cell Sci. 116:2003;1127-1136
    • (2003) J Cell Sci , vol.116 , pp. 1127-1136
    • Herreman, A.1    Van Gassen, G.2    Bentahir, M.3    Nyabi, O.4    Craessaerts, K.5    Mueller, U.6
  • 49
    • 0026454256 scopus 로고
    • Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases
    • Hof P., Bouras C., Buee L., Delacourte A., Perl D., Morrison J. Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. Acta Neuropathol (Berl). 85:1992;23-30
    • (1992) Acta Neuropathol (Berl) , vol.85 , pp. 23-30
    • Hof, P.1    Bouras, C.2    Buee, L.3    Delacourte, A.4    Perl, D.5    Morrison, J.6
  • 50
    • 0029952871 scopus 로고    scopus 로고
    • The neuropathological changes associated with normal brain aging
    • Hof P., Glannakopoulos P., Bouras C. The neuropathological changes associated with normal brain aging. Histol Histopathol. 11:1996;1075-1088
    • (1996) Histol Histopathol , vol.11 , pp. 1075-1088
    • Hof, P.1    Glannakopoulos, P.2    Bouras, C.3
  • 51
    • 0025832182 scopus 로고
    • Neuropathological observations in a case of autism presenting with self-injury behavior
    • Hof P., Knabe R., Bovier P., Bouras C. Neuropathological observations in a case of autism presenting with self-injury behavior. Acta Neuropathol (Berl). 82:1991;321-326
    • (1991) Acta Neuropathol (Berl) , vol.82 , pp. 321-326
    • Hof, P.1    Knabe, R.2    Bovier, P.3    Bouras, C.4
  • 52
    • 0002377794 scopus 로고
    • The cellular basis of cortical disconnection in Alzheimer disease and related dementing conditions
    • Terry R, Katzman R, Bick K, editors. New York: Raven Press;
    • Hof P, Morrison J. The cellular basis of cortical disconnection in Alzheimer disease and related dementing conditions. In: Terry R, Katzman R, Bick K, editors. Alzheimer disease. New York: Raven Press; 1994. p. 197-229.
    • (1994) Alzheimer Disease , pp. 197-229
    • Hof, P.1    Morrison, J.2
  • 53
    • 0031914718 scopus 로고    scopus 로고
    • Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
    • Holcomb L., Gordon M., McGowan E., Yu X., Benkovic S., Jantzen P., et al. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med. 4:1998;97-100
    • (1998) Nat Med , vol.4 , pp. 97-100
    • Holcomb, L.1    Gordon, M.2    McGowan, E.3    Yu, X.4    Benkovic, S.5    Jantzen, P.6
  • 54
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits Aβ elevation and amyloid plaques in transgenic mice
    • Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., et al. Correlative memory deficits Aβ elevation and amyloid plaques in transgenic mice. Science. 274:1996;99-102
    • (1996) Science , vol.274 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3    Eckman, C.4    Harigaya, Y.5
  • 55
    • 0032543684 scopus 로고    scopus 로고
    • Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
    • Hutton M., Lendon C., Rizzu P., Baker M., Froelich S., Houlden H., et al. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 393:1998;702-705
    • (1998) Nature , vol.393 , pp. 702-705
    • Hutton, M.1    Lendon, C.2    Rizzu, P.3    Baker, M.4    Froelich, S.5    Houlden, H.6
  • 56
    • 0030611097 scopus 로고    scopus 로고
    • Abeta deposition is associated with neuropil changes but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse
    • Irizarry M., Soriano F., Mcnarmara M., Page K., Schenk D., Hyman B. Abeta deposition is associated with neuropil changes but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J Neurosci. 17:1997;7053-7059
    • (1997) J Neurosci , vol.17 , pp. 7053-7059
    • Irizarry, M.1    Soriano, F.2    McNarmara, M.3    Page, K.4    Schenk, D.5    Hyman, B.6
  • 57
    • 0031949083 scopus 로고    scopus 로고
    • Senile dementia with tangles (tangle predominant form of senile dementia)
    • Jellinger K., Bancher C. Senile dementia with tangles (tangle predominant form of senile dementia). Brain Pathol. 8:1998;367-376
    • (1998) Brain Pathol , vol.8 , pp. 367-376
    • Jellinger, K.1    Bancher, C.2
  • 58
    • 0030678158 scopus 로고    scopus 로고
    • Alzheimer's disease: Risk and protection
    • Jorm A. Alzheimer's disease: risk and protection. Med J Aust. 167:1997;443-446
    • (1997) Med J Aust , vol.167 , pp. 443-446
    • Jorm, A.1
  • 59
    • 0031900410 scopus 로고    scopus 로고
    • Relating anatomy to function in Alzheimer's disease: Neuropsychological profiles predict regional neuropathology 5 years later
    • Kanne S., Balota D., Storandt M., McKeel D., Morris J. Relating anatomy to function in Alzheimer's disease: neuropsychological profiles predict regional neuropathology 5 years later. Neurology. 50:1998;979-985
    • (1998) Neurology , vol.50 , pp. 979-985
    • Kanne, S.1    Balota, D.2    Storandt, M.3    McKeel, D.4    Morris, J.5
  • 61
    • 0242668337 scopus 로고    scopus 로고
    • Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
    • Kayed R., Head E., Thompson J., Mclntire T., Milton S., Cotman C., et al. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science. 300:2003;486-489
    • (2003) Science , vol.300 , pp. 486-489
    • Kayed, R.1    Head, E.2    Thompson, J.3    McLntire, T.4    Milton, S.5    Cotman, C.6
  • 62
    • 0031593784 scopus 로고    scopus 로고
    • Aβ associated neuropil changes: Correlation with neuronal loss and dementia
    • Knowles R., Gomez-Isla T., Hyman B. Aβ associated neuropil changes: correlation with neuronal loss and dementia. J Neuropathol Exp Neurol. 57:1998;1122-1130
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 1122-1130
    • Knowles, R.1    Gomez-Isla, T.2    Hyman, B.3
  • 63
    • 0033609008 scopus 로고    scopus 로고
    • Plaque-induced neurite abnormalities: Implications for disruption of neural networks in Alzheimer's disease
    • Knowles R., Wyart C., Buldyrev S., Cruz L., Urbane B., Hasselmo M., et al. Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease. Proc Natl Acad Sci USA. 96:1999;5274-5279
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5274-5279
    • Knowles, R.1    Wyart, C.2    Buldyrev, S.3    Cruz, L.4    Urbane, B.5    Hasselmo, M.6
  • 64
    • 0026646328 scopus 로고
    • In vivo neurotoxicity of beta-amyloid [β(1-40)] and the β(25-35) fragment
    • Kowall N.W., McKee A., Yankner B., Beal M. In vivo neurotoxicity of beta-amyloid [β(1-40)] and the β(25-35) fragment. Neurobiol Aging. 13:1992;537-542
    • (1992) Neurobiol Aging , vol.13 , pp. 537-542
    • Kowall, N.W.1    McKee, A.2    Yankner, B.3    Beal, M.4
  • 65
    • 0036955813 scopus 로고    scopus 로고
    • Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation
    • Kril J., Patel S., Harding A., Halliday G. Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation. Acta Neuropathol (Berl). 103:2002;370-376
    • (2002) Acta Neuropathol (Berl) , vol.103 , pp. 370-376
    • Kril, J.1    Patel, S.2    Harding, A.3    Halliday, G.4
  • 66
    • 11544279355 scopus 로고    scopus 로고
    • Diffusible, nonfibrillar ligands derived from Abetal-42 are potent central nervous system neurotoxins
    • Lambert M., Barlow A., Chromy B., Edwards C., Freed R., Liosatos M., et al. Diffusible, nonfibrillar ligands derived from Abetal-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA. 95:1998;6448-6453
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6448-6453
    • Lambert, M.1    Barlow, A.2    Chromy, B.3    Edwards, C.4    Freed, R.5    Liosatos, M.6
  • 67
    • 0037130174 scopus 로고    scopus 로고
    • Neurodegenerative disease: Amyloid pores from pathogenic mutations
    • Lashuel H., Hartley D., Petre B., Walz T., Lansbury P. Neurodegenerative disease: amyloid pores from pathogenic mutations. Nature. 418:2002;291
    • (2002) Nature , vol.418 , pp. 291
    • Lashuel, H.1    Hartley, D.2    Petre, B.3    Walz, T.4    Lansbury, P.5
  • 68
    • 0037111837 scopus 로고    scopus 로고
    • Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice
    • Lazarov O., Lee M., Peterson D., Sisodia S. Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice. J Neurosci. 22:2002;9785-9793
    • (2002) J Neurosci , vol.22 , pp. 9785-9793
    • Lazarov, O.1    Lee, M.2    Peterson, D.3    Sisodia, S.4
  • 70
    • 17944382037 scopus 로고    scopus 로고
    • Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
    • Lewis J., Dickson D., Lin W., Chisholm L., Corral A., Jones G., et al. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science. 293:2001;1487-1491
    • (2001) Science , vol.293 , pp. 1487-1491
    • Lewis, J.1    Dickson, D.2    Lin, W.3    Chisholm, L.4    Corral, A.5    Jones, G.6
  • 71
    • 0034621824 scopus 로고    scopus 로고
    • Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1
    • Li Y., Xu M., Lai M., Huang Q., Castro J., DiMuzio-Mower J., et al. Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1. Nature. 405:2000;689-694
    • (2000) Nature , vol.405 , pp. 689-694
    • Li, Y.1    Xu, M.2    Lai, M.3    Huang, Q.4    Castro, J.5    Dimuzio-Mower, J.6
  • 72
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley R. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 240:1988;622-630
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.1
  • 73
    • 0024503377 scopus 로고
    • The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome
    • Mann D., Esiri M. The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome. J Neurol Sci. 89:1989;169-179
    • (1989) J Neurol Sci , vol.89 , pp. 169-179
    • Mann, D.1    Esiri, M.2
  • 74
    • 0022919237 scopus 로고
    • The topography of plaques and tangles in Down's syndrome patients of different ages
    • Mann D., Yates P., Marcyniuk B., Ravindra C. The topography of plaques and tangles in Down's syndrome patients of different ages. J Neuropathol Appl Neurobiol. 12:1986;447-457
    • (1986) J Neuropathol Appl Neurobiol , vol.12 , pp. 447-457
    • Mann, D.1    Yates, P.2    Marcyniuk, B.3    Ravindra, C.4
  • 76
    • 85007768150 scopus 로고    scopus 로고
    • Alzheimer's disease
    • Masters C., Beyreuther K. Alzheimer's disease. BMJ. 316:1998;446-448
    • (1998) BMJ , vol.316 , pp. 446-448
    • Masters, C.1    Beyreuther, K.2
  • 77
    • 0029018224 scopus 로고
    • Synergistic effects of traumatic head injury and apolipoprotein-ε4 in patients with Alzheimer's disease
    • Mayeux R., Ottman R., Maestre G., Ngai C., Tang M., Ginsberg H., et al. Synergistic effects of traumatic head injury and apolipoprotein-ε4 in patients with Alzheimer's disease. Neurology. 45:1995;555-557
    • (1995) Neurology , vol.45 , pp. 555-557
    • Mayeux, R.1    Ottman, R.2    Maestre, G.3    Ngai, C.4    Tang, M.5    Ginsberg, H.6
  • 78
    • 0030249956 scopus 로고    scopus 로고
    • Comparative investigation of neurofibrillary damage in the temporal lobe in Alzheimer's disease Down's syndrome and dementia pugilistica
    • McKenzie J., Roberts G., Royston M. Comparative investigation of neurofibrillary damage in the temporal lobe in Alzheimer's disease Down's syndrome and dementia pugilistica. Neurodegeneration. 5:1996;259-264
    • (1996) Neurodegeneration , vol.5 , pp. 259-264
    • McKenzie, J.1    Roberts, G.2    Royston, M.3
  • 79
    • 0033230623 scopus 로고    scopus 로고
    • Neuroplasticity failure in Alzheimer's disease: Bridging the gap between plaques and tangles
    • Mesulam M. Neuroplasticity failure in Alzheimer's disease: bridging the gap between plaques and tangles. Neuron. 24:1999;521-529
    • (1999) Neuron , vol.24 , pp. 521-529
    • Mesulam, M.1
  • 80
    • 0035168927 scopus 로고    scopus 로고
    • Pathologic correlates of nondemented aging mild cognitive impairment, and early-stage Alzheimer's disease
    • Morris J., Price A. Pathologic correlates of nondemented aging mild cognitive impairment, and early-stage Alzheimer's disease. J Mol Neurosci. 17:2001;101-118
    • (2001) J Mol Neurosci , vol.17 , pp. 101-118
    • Morris, J.1    Price, A.2
  • 81
    • 0025913996 scopus 로고
    • Head trauma as a risk factor for Alzheimer's disease: A collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group
    • Mortimer J., van Duijn C., Chandra V., Fratiglioni L., Graves A., Heyman A., et al. Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group. Int J Epidemiol. 20(Suppl 2):1991;28-35
    • (1991) Int J Epidemiol , vol.20 , Issue.SUPPL. 2 , pp. 28-35
    • Mortimer, J.1    Van Duijn, C.2    Chandra, V.3    Fratiglioni, L.4    Graves, A.5    Heyman, A.6
  • 82
    • 0024602541 scopus 로고
    • Age-related changes in the density and morphology of plaques and neurofibrillary tangles in Down syndrome brain
    • Motte J., Williams R. Age-related changes in the density and morphology of plaques and neurofibrillary tangles in Down syndrome brain. Acta Neuropathol. 77:1989;535-546
    • (1989) Acta Neuropathol , vol.77 , pp. 535-546
    • Motte, J.1    Williams, R.2
  • 83
    • 0026907151 scopus 로고
    • A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid
    • Mullan M., Crawford F., Axelman K., Houlden H., Lilius L., Winblad B., et al. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nat Genet. 1:1992;345-347
    • (1992) Nat Genet , vol.1 , pp. 345-347
    • Mullan, M.1    Crawford, F.2    Axelman, K.3    Houlden, H.4    Lilius, L.5    Winblad, B.6
  • 84
    • 0025950987 scopus 로고
    • A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease
    • Murrell J., Farlow M., Ghetti B., Benson M. A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science. 254:1991;97-99
    • (1991) Science , vol.254 , pp. 97-99
    • Murrell, J.1    Farlow, M.2    Ghetti, B.3    Benson, M.4
  • 85
    • 0034068261 scopus 로고    scopus 로고
    • Brain trauma in aged transgenic mice induces regression of established abeta deposits
    • Nakagawa Y., Reed L., Nakamura M., Mclntosh T., Smith D., Saatman K., et al. Brain trauma in aged transgenic mice induces regression of established abeta deposits. Exp Neurol. 163:2000;244-252
    • (2000) Exp Neurol , vol.163 , pp. 244-252
    • Nakagawa, Y.1    Reed, L.2    Nakamura, M.3    McLntosh, T.4    Smith, D.5    Saatman, K.6
  • 86
    • 0038117796 scopus 로고    scopus 로고
    • Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline [see comments]
    • Näslund J., Haroutunian V., Mohs R., Davis K., Davies P., Greengard P., et al. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline [see comments]. JAMA. 283:2000;1571-1577
    • (2000) JAMA , vol.283 , pp. 1571-1577
    • Näslund, J.1    Haroutunian, V.2    Mohs, R.3    Davis, K.4    Davies, P.5    Greengard, P.6
  • 87
    • 0006325405 scopus 로고    scopus 로고
    • Alzheimer's disease: A re-examination of the amyloid hypothesis
    • Neve R., Robakis N. Alzheimer's disease: a re-examination of the amyloid hypothesis. Trends Neurosci. 21:1998;15-19
    • (1998) Trends Neurosci , vol.21 , pp. 15-19
    • Neve, R.1    Robakis, N.2
  • 88
    • 0026661706 scopus 로고
    • Accumulation of amyloid precursor protein and beta-protein immunoreactivities in axons injured by cerebral infarct
    • Nukina N., Kanazawa I., Mannen T., Uchida Y. Accumulation of amyloid precursor protein and beta-protein immunoreactivities in axons injured by cerebral infarct. Gerontology. 38(Suppl 1):1992;10-14
    • (1992) Gerontology , vol.38 , Issue.SUPPL. 1 , pp. 10-14
    • Nukina, N.1    Kanazawa, I.2    Mannen, T.3    Uchida, Y.4
  • 89
    • 0042697305 scopus 로고    scopus 로고
    • Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
    • Oddo S., Caccamo A., Shepherd J., Murphy M., Golde T., Kayed R., et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron. 39:2003;409-421
    • (2003) Neuron , vol.39 , pp. 409-421
    • Oddo, S.1    Caccamo, A.2    Shepherd, J.3    Murphy, M.4    Golde, T.5    Kayed, R.6
  • 90
    • 0023513805 scopus 로고
    • A quantitative study of frontal cortex dendritic microtubules in patients with Alzheimer's disease
    • Paula-Barbosa M., Tavares M., Cadete-Leite A. A quantitative study of frontal cortex dendritic microtubules in patients with Alzheimer's disease. Brain Res. 416:1987;139-142
    • (1987) Brain Res , vol.416 , pp. 139-142
    • Paula-Barbosa, M.1    Tavares, M.2    Cadete-Leite, A.3
  • 92
    • 0025992417 scopus 로고
    • In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity
    • Pike C., Walencewicz A., Glabe C., Cotman C.W. In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563:1991;311-314
    • (1991) Brain Res , vol.563 , pp. 311-314
    • Pike, C.1    Walencewicz, A.2    Glabe, C.3    Cotman, C.W.4
  • 94
    • 0343404671 scopus 로고    scopus 로고
    • Amyloid burden determined by image analysis correlates with conventional histochemical method and clinical measures of cognitive decline
    • Poulos B., Crystal H., Katz M., Kuslansky G., Grober E., Lipton R., et al. Amyloid burden determined by image analysis correlates with conventional histochemical method and clinical measures of cognitive decline. J Neuropathol Exp Neurol. 56:1997;615
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 615
    • Poulos, B.1    Crystal, H.2    Katz, M.3    Kuslansky, G.4    Grober, E.5    Lipton, R.6
  • 95
    • 0030049915 scopus 로고    scopus 로고
    • Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease
    • Praprotnik D., Smith M., Richey P., Vinters H., Perry G. Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease. Acta Neuropathol. 91:1996;226-235
    • (1996) Acta Neuropathol , vol.91 , pp. 226-235
    • Praprotnik, D.1    Smith, M.2    Richey, P.3    Vinters, H.4    Perry, G.5
  • 97
    • 0028937766 scopus 로고
    • Head injury as a risk factor in Alzheimer's disease
    • Rasmusson D., Brandt J., Martin D., Folstein M. Head injury as a risk factor in Alzheimer's disease. Brain Inj. 3:1995;213-219
    • (1995) Brain Inj , vol.3 , pp. 213-219
    • Rasmusson, D.1    Brandt, J.2    Martin, D.3    Folstein, M.4
  • 99
    • 0028174629 scopus 로고
    • Beta amyloid protein deposition in the brain after severe head injury: Implications for the pathogenesis of Alzheimer's disease
    • Roberts G., Gentleman S., Lynch A., Murray L., Landon M., Graham D. Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease. J Neurol Neurosurg Psychiatry. 57:1994;419-425
    • (1994) J Neurol Neurosurg Psychiatry , vol.57 , pp. 419-425
    • Roberts, G.1    Gentleman, S.2    Lynch, A.3    Murray, L.4    Landon, M.5    Graham, D.6
  • 100
    • 0031149760 scopus 로고    scopus 로고
    • The cellular basis for the relative resistance of parvalbumin and calretinin immunoreactive neocortical neurons to the pathology of Alzheimer's disease
    • Sampson V., Morrison J., Vickers J. The cellular basis for the relative resistance of parvalbumin and calretinin immunoreactive neocortical neurons to the pathology of Alzheimer's disease. Exp Neurol. 145:1997;295-302
    • (1997) Exp Neurol , vol.145 , pp. 295-302
    • Sampson, V.1    Morrison, J.2    Vickers, J.3
  • 101
    • 0029164285 scopus 로고
    • Relationship of amyloid beta/A4 protein to the neurofibrillary tangles in Guamanian Parkinsonism-dementia
    • Schwab C., Steele J., Akiyama H., McGeer E., McGeer P. Relationship of amyloid beta/A4 protein to the neurofibrillary tangles in Guamanian Parkinsonism-dementia. Acta Neuropathol (Berl). 90:1995;287-298
    • (1995) Acta Neuropathol (Berl) , vol.90 , pp. 287-298
    • Schwab, C.1    Steele, J.2    Akiyama, H.3    McGeer, E.4    McGeer, P.5
  • 102
    • 0037111838 scopus 로고    scopus 로고
    • Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis
    • Sheng J., Price D., Koliatsos V. Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis. J Neurosci. 22:2002;9794-9799
    • (2002) J Neurosci , vol.22 , pp. 9794-9799
    • Sheng, J.1    Price, D.2    Koliatsos, V.3
  • 103
    • 0001719387 scopus 로고
    • Histologische Studien iiber die senile demenz
    • Simchowicz T. Histologische Studien iiber die senile demenz. Histol Histopathol Arb. 4:1910;267
    • (1910) Histol Histopathol Arb , vol.4 , pp. 267
    • Simchowicz, T.1
  • 104
    • 0032860822 scopus 로고    scopus 로고
    • Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig
    • Smith D., Chen X., Nonaka M., Trojanowski J., Lee V., Saatman K., et al. Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig. J Neuropathol Exp Neurol. 58:1999;982-992
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 982-992
    • Smith, D.1    Chen, X.2    Nonaka, M.3    Trojanowski, J.4    Lee, V.5    Saatman, K.6
  • 106
    • 0037128935 scopus 로고    scopus 로고
    • Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
    • Stamer K., Vogel R., Thies E., Mandelkow E., Mandelkow E. Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J Cell Biol. 156:2002;1051-1063
    • (2002) J Cell Biol , vol.156 , pp. 1051-1063
    • Stamer, K.1    Vogel, R.2    Thies, E.3    Mandelkow, E.4    Mandelkow, E.5
  • 107
    • 0033452874 scopus 로고    scopus 로고
    • Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease
    • Steiner H., Capell A., Leimer U., Haass C. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease. Eur Arch Psychiatry Clin Neurosci. 249:1999;266-270
    • (1999) Eur Arch Psychiatry Clin Neurosci , vol.249 , pp. 266-270
    • Steiner, H.1    Capell, A.2    Leimer, U.3    Haass, C.4
  • 108
    • 0026783914 scopus 로고
    • In vivo effects of beta-amyloid implants in rodents: Lack of potentiation of damage associated with transient global forebrain ischemia
    • Stephenson D., Clemens J. In vivo effects of beta-amyloid implants in rodents: lack of potentiation of damage associated with transient global forebrain ischemia. Brain Res. 586:1992;235-246
    • (1992) Brain Res , vol.586 , pp. 235-246
    • Stephenson, D.1    Clemens, J.2
  • 110
    • 0027427734 scopus 로고
    • Toxic effect of a beta-amyloid peptide (beta-22-35) on the hippocampal neuron and its prevention
    • Takadera T., Sakura N., Mohri T., Hashimoto T. Toxic effect of a beta-amyloid peptide (beta-22-35) on the hippocampal neuron and its prevention. Neurosci Lett. 161:1993;41-44
    • (1993) Neurosci Lett , vol.161 , pp. 41-44
    • Takadera, T.1    Sakura, N.2    Mohri, T.3    Hashimoto, T.4
  • 111
    • 0028587336 scopus 로고
    • APP717 missense mutation affects the ratio of amyloid beta protein species (a beta 1-42/43 and a beta 1-40) in familial Alzheimer's disease brain
    • Tamaoka A., Odaka A., Ishibashi Y., Usami M., Sahara N., Suzuki N., et al. APP717 missense mutation affects the ratio of amyloid beta protein species (a beta 1-42/43 and a beta 1-40) in familial Alzheimer's disease brain. J Biol Chem. 269:1994;32721-32724
    • (1994) J Biol Chem , vol.269 , pp. 32721-32724
    • Tamaoka, A.1    Odaka, A.2    Ishibashi, Y.3    Usami, M.4    Sahara, N.5    Suzuki, N.6
  • 112
    • 0028218871 scopus 로고
    • Neuropathological changes in Alzheimer disease
    • Terry R. Neuropathological changes in Alzheimer disease. Prog Brain Res. 101:1994;383-390
    • (1994) Prog Brain Res , vol.101 , pp. 383-390
    • Terry, R.1
  • 113
    • 0029795197 scopus 로고    scopus 로고
    • The pathogenesis of Alzheimer disease: An alternative to the amyloid hypothesis
    • Terry R. The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis. J Neuropathol Exp Neurol. 55:1996;1023-1025
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 1023-1025
    • Terry, R.1
  • 114
    • 0025784849 scopus 로고
    • Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid beta-protein and tau protein
    • Tokuda T., Ikeda S., Yanagisawa N., Ihara Y., Glenner G. Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid beta-protein and tau protein. Acta Neuropathol (Berl). 82:1991;280-285
    • (1991) Acta Neuropathol (Berl) , vol.82 , pp. 280-285
    • Tokuda, T.1    Ikeda, S.2    Yanagisawa, N.3    Ihara, Y.4    Glenner, G.5
  • 115
    • 0036311615 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis/Parkinsonism dementia complex: Transgenic mice provide insights into mechanisms underlying a common tauopathy in an ethnic minority on Guam
    • Trojanowski J., Ishihara T., Higuchi M., Yoshiyama Y., Hong M., Zhang B., et al. Amyotrophic lateral sclerosis/Parkinsonism dementia complex: transgenic mice provide insights into mechanisms underlying a common tauopathy in an ethnic minority on Guam. Exp Neurol. 176:2002;1-11
    • (2002) Exp Neurol , vol.176 , pp. 1-11
    • Trojanowski, J.1    Ishihara, T.2    Higuchi, M.3    Yoshiyama, Y.4    Hong, M.5    Zhang, B.6
  • 116
    • 0037080159 scopus 로고    scopus 로고
    • Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis
    • Uryu K., Laurer H., Mclntosh T., Pratico D., Martinez D., Leight S., et al. Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis. J Neurosci. 22:2002;446-454
    • (2002) J Neurosci , vol.22 , pp. 446-454
    • Uryu, K.1    Laurer, H.2    McLntosh, T.3    Pratico, D.4    Martinez, D.5    Leight, S.6
  • 117
    • 22444451805 scopus 로고    scopus 로고
    • Genetics of Alzheimer's disease: What have we learned ?
    • Van Broeckhoven C. Genetics of Alzheimer's disease: what have we learned ? Alzheimer's Rep. 1(Suppl):1998;21-22
    • (1998) Alzheimer's Rep , vol.1 , Issue.SUPPL. , pp. 21-22
    • Van Broeckhoven, C.1
  • 118
    • 0037756809 scopus 로고    scopus 로고
    • Diffuse amyloid deposition but not plaque number, is reduced in amyloid precursor protein/presenilin 1 double-transgenic mice by pathway lesions
    • Van Groen T., Liu L., Ikonen S., Kadish I. Diffuse amyloid deposition but not plaque number, is reduced in amyloid precursor protein/presenilin 1 double-transgenic mice by pathway lesions. Neuroscience. 119:2003;1185-1197
    • (2003) Neuroscience , vol.119 , pp. 1185-1197
    • Van Groen, T.1    Liu, L.2    Ikonen, S.3    Kadish, I.4
  • 119
    • 0034617297 scopus 로고    scopus 로고
    • Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1
    • Verdile G., Martins R., Duthie M., Holmes E., St George-Hyslop P., Fraser P. Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1. J Biol Chem. 275:2000;20794-20798
    • (2000) J Biol Chem , vol.275 , pp. 20794-20798
    • Verdile, G.1    Martins, R.2    Duthie, M.3    Holmes, E.4    St George-Hyslop, P.5    Fraser, P.6
  • 121
    • 0030249343 scopus 로고    scopus 로고
    • Dystrophic neurite formation associates with age-related β amyloid deposition in the neocortex: Clues to the genesis of neurofibrillary pathology
    • Vickers J., Chin D., Edwards A., Sampson V., Harper C., Morrison J. Dystrophic neurite formation associates with age-related β amyloid deposition in the neocortex: clues to the genesis of neurofibrillary pathology. Exp Neurol. 141:1996;1-11
    • (1996) Exp Neurol , vol.141 , pp. 1-11
    • Vickers, J.1    Chin, D.2    Edwards, A.3    Sampson, V.4    Harper, C.5    Morrison, J.6
  • 123
    • 0033600228 scopus 로고    scopus 로고
    • A stop-codon mutation in the BRI gene associated with familial British dementia
    • Vidal R., Frangione B., Rostagno A., Mead S., Revesz T., Plant G., et al. A stop-codon mutation in the BRI gene associated with familial British dementia. Nature. 399:1999;776-781
    • (1999) Nature , vol.399 , pp. 776-781
    • Vidal, R.1    Frangione, B.2    Rostagno, A.3    Mead, S.4    Revesz, T.5    Plant, G.6
  • 124
    • 0032521111 scopus 로고    scopus 로고
    • Fibrillar beta-amyloid induces microglial phagocytosis expression of inducible nitric oxide synthase and loss of a select population of neurons in the rat CNS in vivo
    • Weldon D., Rogers S., Ghilardi J., Finke M., Cleary J., O'Hare E., et al. Fibrillar beta-amyloid induces microglial phagocytosis expression of inducible nitric oxide synthase and loss of a select population of neurons in the rat CNS in vivo. J Neurosci. 18:1998;2161-2173
    • (1998) J Neurosci , vol.18 , pp. 2161-2173
    • Weldon, D.1    Rogers, S.2    Ghilardi, J.3    Finke, M.4    Cleary, J.5    O'Hare, E.6
  • 125
    • 0021956826 scopus 로고
    • Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome
    • Wisniewski K., Wisniewski H., Wen G. Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Ann Neurol. 17:1985;272-282
    • (1985) Ann Neurol , vol.17 , pp. 272-282
    • Wisniewski, K.1    Wisniewski, H.2    Wen, G.3
  • 126
    • 0033535553 scopus 로고    scopus 로고
    • Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
    • Wolfe M., Xia W., Ostaszewski B., Diehl T., Kimberly W., Selkoe D. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature. 398:1999;513-517
    • (1999) Nature , vol.398 , pp. 513-517
    • Wolfe, M.1    Xia, W.2    Ostaszewski, B.3    Diehl, T.4    Kimberly, W.5    Selkoe, D.6
  • 127
    • 0029896354 scopus 로고    scopus 로고
    • Mechanisms of neuronal degeneration in Alzheimer's disease
    • Yankner B. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron. 16:1996;921-932
    • (1996) Neuron , vol.16 , pp. 921-932
    • Yankner, B.1
  • 128
    • 0036377156 scopus 로고    scopus 로고
    • Amyloid-fibril formation. Proposed mechanisms and relevance to conformational disease
    • Zerovnik E. Amyloid-fibril formation. Proposed mechanisms and relevance to conformational disease. Eur J Biochem. 269:2002;3362-3371
    • (2002) Eur J Biochem , vol.269 , pp. 3362-3371
    • Zerovnik, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.