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Volumn 91, Issue 3, 1996, Pages 226-235

Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease

Author keywords

protein precursor; Amyloid ; Axonal transport; Cytoskeleton; Neurofilaments

Indexed keywords

ADULT; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BRAIN BIOPSY; CASE REPORT; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOSKELETON; DYSTROPHY; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MORPHOLOGY; NERVE FIBER TRANSPORT; NEURITE; NEUROFILAMENT; PRIORITY JOURNAL; SENILE PLAQUE;

EID: 0030049915     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050420     Document Type: Article
Times cited : (92)

References (49)
  • 2
    • 0025355591 scopus 로고
    • Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: Evidence for a neuronal origin
    • Cataldo AM, Thayer CY, Bird ED, Wheelock TR, Nixon RA (1990) Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin. Brain Res 513:181-192
    • (1990) Brain Res , vol.513 , pp. 181-192
    • Cataldo, A.M.1    Thayer, C.Y.2    Bird, E.D.3    Wheelock, T.R.4    Nixon, R.A.5
  • 5
    • 0023197393 scopus 로고
    • Transformation of degenerating neurofibrils into amyloid substance in Alzheimer's disease: Histochemical and immunohistochemical studies
    • Defossez A, Delacourte AJ (1987) Transformation of degenerating neurofibrils into amyloid substance in Alzheimer's disease: histochemical and immunohistochemical studies. J Neurol Sci 81:1-10
    • (1987) J Neurol Sci , vol.81 , pp. 1-10
    • Defossez, A.1    Delacourte, A.J.2
  • 6
    • 0022413549 scopus 로고
    • AVEC-DIC and electron microscopic analyses of axonally transported particles in cold-blocked squid giant axons
    • Fahim MA, Lasek RJ, Brady ST, Hodge A (1985) AVEC-DIC and electron microscopic analyses of axonally transported particles in cold-blocked squid giant axons. J Neurocytol 14:689-704
    • (1985) J Neurocytol , vol.14 , pp. 689-704
    • Fahim, M.A.1    Lasek, R.J.2    Brady, S.T.3    Hodge, A.4
  • 8
    • 0023766743 scopus 로고
    • MAP2 is a component of crossbridges between microtubules and neurofilaments in the neuronal cytoskeleton: Quick-freeze, deep-etch immunoelectron microscopy and reconstitution studies
    • Hirokawa N, Hisanaga S, Shiomura Y (1988) MAP2 is a component of crossbridges between microtubules and neurofilaments in the neuronal cytoskeleton: quick-freeze, deep-etch immunoelectron microscopy and reconstitution studies. J Neurosci 8:2769-2779
    • (1988) J Neurosci , vol.8 , pp. 2769-2779
    • Hirokawa, N.1    Hisanaga, S.2    Shiomura, Y.3
  • 9
    • 0024467482 scopus 로고
    • Anomalous accumulation of tau and ubiquitin immunoreactivities in rat brain caused by protease inhibition and by normal aging: A clue to PHF pathogenesis?
    • Ivy GO, Kitani K, Ihara Y (1989) Anomalous accumulation of tau and ubiquitin immunoreactivities in rat brain caused by protease inhibition and by normal aging: a clue to PHF pathogenesis? Brain Res 498:360-365
    • (1989) Brain Res , vol.498 , pp. 360-365
    • Ivy, G.O.1    Kitani, K.2    Ihara, Y.3
  • 10
    • 0344237032 scopus 로고
    • A 38,000-dalton membrane protein (p38) present in synaptic vesicles
    • Jahn R, Schiebler W, Ouimet C, Greengard P (1985) A 38,000-dalton membrane protein (p38) present in synaptic vesicles. Proc Natl Acad Sci USA 82:4137-4141
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4137-4141
    • Jahn, R.1    Schiebler, W.2    Ouimet, C.3    Greengard, P.4
  • 12
    • 0022414054 scopus 로고
    • Diagnosis of Alzheimer's disease
    • Khachaturian ZS (1985) Diagnosis of Alzheimer's disease. Arch Neurol 42: 1097-1105
    • (1985) Arch Neurol , vol.42 , pp. 1097-1105
    • Khachaturian, Z.S.1
  • 13
    • 0001120692 scopus 로고
    • Alzheimer's disease - An electron microscopical study
    • Kidd M (1964) Alzheimer's disease - an electron microscopical study. Brain 876:307-320
    • (1964) Brain , vol.876 , pp. 307-320
    • Kidd, M.1
  • 15
    • 0021739339 scopus 로고
    • Microtubule-associated protein 2: Monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles
    • Kosik KS, Duffy LK, Dowling MM, Abraham C, McCluskey A, Selkoe DJ (1984) Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles. Proc Natl Acad Sci USA 81:7941-7945
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 7941-7945
    • Kosik, K.S.1    Duffy, L.K.2    Dowling, M.M.3    Abraham, C.4    McCluskey, A.5    Selkoe, D.J.6
  • 17
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34:939-944
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 18
    • 0024009778 scopus 로고
    • In vitro polymorphism and phase transitions of the neurofilamentous network isolated from the giant axon of the squid
    • Metuzals J, Pant H, Gainer H, Eagles PA, White NS, Houghton S (1988) In vitro polymorphism and phase transitions of the neurofilamentous network isolated from the giant axon of the squid. Cell Tissue Res 252:249-262
    • (1988) Cell Tissue Res , vol.252 , pp. 249-262
    • Metuzals, J.1    Pant, H.2    Gainer, H.3    Eagles, P.A.4    White, N.S.5    Houghton, S.6
  • 21
    • 0022398557 scopus 로고
    • Cross-bridges mediate anterograde and retroarade vesicle transport along microtubules in squid axoplasm
    • Miller RH, Lasek RJ (1985) Cross-bridges mediate anterograde and retroarade vesicle transport along microtubules in squid axoplasm J Cell Biol 101:2181-2193
    • (1985) J Cell Biol , vol.101 , pp. 2181-2193
    • Miller, R.H.1    Lasek, R.J.2
  • 22
    • 0023066791 scopus 로고
    • Preferred microtubules for vesicle transport in lobster axons
    • Miller RH, Lasek RJ, Katz MJ (1987) Preferred microtubules for vesicle transport in lobster axons. Science 235: 220-222
    • (1987) Science , vol.235 , pp. 220-222
    • Miller, R.H.1    Lasek, R.J.2    Katz, M.J.3
  • 23
    • 0023032310 scopus 로고
    • Protein p38: An integral membrane protein specific for small vesicles of neurons and neuroendocrine cells
    • Navone F, John R, Di Gioia G, Stukenbrok H, Greengard P, De Camilli P (1986) Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells. J Cell Biol 103:2511-2527
    • (1986) J Cell Biol , vol.103 , pp. 2511-2527
    • Navone, F.1    John, R.2    Di Gioia, G.3    Stukenbrok, H.4    Greengard, P.5    De Camilli, P.6
  • 24
    • 0027132358 scopus 로고
    • Senile plaques and neurofibrillary tangles: What role do they play in Alzheimer's disease?
    • Perry G, Smith MA (1993) Senile plaques and neurofibrillary tangles: what role do they play in Alzheimer's disease? Clin Neurosci 1:199-203
    • (1993) Clin Neurosci , vol.1 , pp. 199-203
    • Perry, G.1    Smith, M.A.2
  • 29
    • 0029655453 scopus 로고    scopus 로고
    • Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer disease: An index of oxidative stress
    • Praprotnik D, Smith MA, Richey PL, Vinters HV, Perry G (1996) Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer disease: an index of oxidative stress. Acta Neuropathol 91:1-5
    • (1996) Acta Neuropathol , vol.91 , pp. 1-5
    • Praprotnik, D.1    Smith, M.A.2    Richey, P.L.3    Vinters, H.V.4    Perry, G.5
  • 30
    • 0024992613 scopus 로고
    • Intracerebroventricular bethanechol for Alzheimer's disease. Variable dose-related responses
    • Read SL, Frazee J, Shapira J, Smith C, Cummings JL, Tomiyasu U (1990) Intracerebroventricular bethanechol for Alzheimer's disease. Variable dose-related responses. Arch Neurol 47:1025-1030
    • (1990) Arch Neurol , vol.47 , pp. 1025-1030
    • Read, S.L.1    Frazee, J.2    Shapira, J.3    Smith, C.4    Cummings, J.L.5    Tomiyasu, U.6
  • 31
    • 0023695434 scopus 로고
    • Inhibition of proteolysis blocks anterograde-retrograde conversion of axonally transported vesicles
    • Sahenk Z, Lasek RJ (1988) Inhibition of proteolysis blocks anterograde-retrograde conversion of axonally transported vesicles. Brain Res 460:199-203
    • (1988) Brain Res , vol.460 , pp. 199-203
    • Sahenk, Z.1    Lasek, R.J.2
  • 32
    • 0023900638 scopus 로고
    • Ubiquitin and microtubule-associated protein tau immunoreactivity each define distinct structures with differing distributions and solubility properties in Alzheimer brain
    • Shaw G, Chau V (1988) Ubiquitin and microtubule-associated protein tau immunoreactivity each define distinct structures with differing distributions and solubility properties in Alzheimer brain. Proc Natl Acad Sci USA 85: 2854-2858
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2854-2858
    • Shaw, G.1    Chau, V.2
  • 34
    • 0025909019 scopus 로고
    • Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease
    • Siedlak SL, Cras P, Kawai M, Richey P, Perry G (1991) Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease. J Histochem Cytochem 39: 899-904
    • (1991) J Histochem Cytochem , vol.39 , pp. 899-904
    • Siedlak, S.L.1    Cras, P.2    Kawai, M.3    Richey, P.4    Perry, G.5
  • 35
    • 0028267251 scopus 로고
    • Alzheimer disease: An imbalance of proteolytic regulation?
    • Smith MA, Perry G (1994) Alzheimer disease: an imbalance of proteolytic regulation? Med Hypotheses 42: 277-279
    • (1994) Med Hypotheses , vol.42 , pp. 277-279
    • Smith, M.A.1    Perry, G.2
  • 39
    • 0025223441 scopus 로고
    • Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome
    • Snow AD, Mar H, Nochlin D, Sekiguchi RT, Kimata K, Koike Y, Wight TN (1990) Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome. Am J Pathol 137: 1253-1270
    • (1990) Am J Pathol , vol.137 , pp. 1253-1270
    • Snow, A.D.1    Mar, H.2    Nochlin, D.3    Sekiguchi, R.T.4    Kimata, K.5    Koike, Y.6    Wight, T.N.7
  • 40
    • 0027104120 scopus 로고
    • A morphometric study of the blood-brain barrier in Alzheimer's disease
    • Stewart PA, Hayakawa K, Akers MA, Vinters HV (1992) A morphometric study of the blood-brain barrier in Alzheimer's disease. Lab Invest 67: 734-742
    • (1992) Lab Invest , vol.67 , pp. 734-742
    • Stewart, P.A.1    Hayakawa, K.2    Akers, M.A.3    Vinters, H.V.4
  • 41
    • 0020520174 scopus 로고
    • Double immunogold staining method for the simultaneous ultrastructural localization of regulatory peptides
    • Tapia FJ, Varndell IM, Probert L, De Mey J, Polak JM (1983) Double immunogold staining method for the simultaneous ultrastructural localization of regulatory peptides. J Histochem Cytochem 31: 977-981
    • (1983) J Histochem Cytochem , vol.31 , pp. 977-981
    • Tapia, F.J.1    Varndell, I.M.2    Probert, L.3    De Mey, J.4    Polak, J.M.5
  • 42
    • 78651158156 scopus 로고
    • Ultrastructural studies in Alzheimer's presenile dementia
    • Terry RD, Gonatas NK, Weiss M (1964) Ultrastructural studies in Alzheimer's presenile dementia. Am J Pathol 44: 269-297
    • (1964) Am J Pathol , vol.44 , pp. 269-297
    • Terry, R.D.1    Gonatas, N.K.2    Weiss, M.3
  • 43
    • 0021291304 scopus 로고
    • 2 (Microtubule-associated protein 2)
    • Shay JW (ed) Plenum Press, New York
    • 2 (Microtubule-associated protein 2). In: Shay JW (ed) Cell and muscle motility. vol 5. Plenum Press, New York, pp 289-311
    • (1984) Cell and Muscle Motility , vol.5 , pp. 289-311
    • Valle, R.B.1
  • 45
    • 0021796959 scopus 로고
    • Subunit structure of paired helical filaments in Alzheimer's disease
    • Wischik CM, Crowther RA, Stewart M, Roth M (1985) Subunit structure of paired helical filaments in Alzheimer's disease. J Cell Biol 100: 1905-1912
    • (1985) J Cell Biol , vol.100 , pp. 1905-1912
    • Wischik, C.M.1    Crowther, R.A.2    Stewart, M.3    Roth, M.4
  • 47
    • 0002898753 scopus 로고
    • Reexamination of the pathogenesis of the senile plaque
    • Zimmermann HM (ed) Grune and Stratton, New York
    • Wisniewski HM, Terry RD (1973) Reexamination of the pathogenesis of the senile plaque. In: Zimmermann HM (ed) Progress in Neuropatholoey. Grune and Stratton, New York, pp 1-26
    • (1973) Progress in Neuropatholoey , pp. 1-26
    • Wisniewski, H.M.1    Terry, R.D.2
  • 48
    • 0024420556 scopus 로고
    • Electron micrograph of diffuse plaques. Initial stage of senile plaque formation in the Alzheimer brain
    • Yamaguchi H, Nakazato Y, Hirai S, Shoji M, Harigaya Y (1989) Electron micrograph of diffuse plaques. Initial stage of senile plaque formation in the Alzheimer brain. Am J Pathol 135: 593-597
    • (1989) Am J Pathol , vol.135 , pp. 593-597
    • Yamaguchi, H.1    Nakazato, Y.2    Hirai, S.3    Shoji, M.4    Harigaya, Y.5
  • 49
    • 0021362813 scopus 로고
    • Evidence that paired helical filaments originate from neurofilaments - Electron microscope observations of neuntes in senile plaques in the brain in Alzheimer's disease
    • Yoshimura N (1984) Evidence that paired helical filaments originate from neurofilaments - electron microscope observations of neuntes in senile plaques in the brain in Alzheimer's disease. Clin Neuropathol 3: 22-27
    • (1984) Clin Neuropathol , vol.3 , pp. 22-27
    • Yoshimura, N.1


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