Bcl-xES, a BH4- and BH2-containing antiapoptotic protein, delays Bax oligomer formation and binds Apaf-1, blocking procaspase-9 activation

Oncogene

Volumn 23, Issue 22, 2004, Pages 3915-3931

  Schmitt, Estelle ^a   Paquet, Claudie ^a   Beauchemin, Myriam ^a   Bertrand, Richard ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Apaf 1; Apoptosis; Bax; Bcl x; Caspase

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BH2 PROTEIN; BH4 PROTEIN; CAMPTOTHECIN; CASPASE; CASPASE 9; CISPLATIN; CYTOCHROME C; ETOPOSIDE; MESSENGER RNA; OLIGOMER; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN SUBUNIT; RIBONUCLEASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; APAF1 PROTEIN, HUMAN; BAX PROTEIN, HUMAN; BCL2L1 PROTEIN, HUMAN; DNA TOPOISOMERASE; ENZYME PRECURSOR; ONCOPROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; BONE MARROW; BREAST; CANCER CELL CULTURE; CELL DEATH; CELL LINE; CHANNEL GATING; CONTROLLED STUDY; CORRELATION ANALYSIS; GEL FILTRATION CHROMATOGRAPHY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LUNG; OVARY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TESTIS; TUMOR; DRUG ANTAGONISM; ENZYME ACTIVATION; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CAMPTOTHECIN; CASPASES; DNA TOPOISOMERASES, TYPE I; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 2542584622     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207554     Document Type: Article

References (103)

1. Adams JM and Cory S. (2001). Trends Biochem. Sci., 26, 61-66.
2. Antonsson B, Conti F, Ciavatta A, Montessuit S, Lewis S, Martinou I, Bernasconi L, Bernard A, Mermod JJ, Mazzei G, Maundrell K, Gambale F, Sadoul R and Martinou JC. (1997). Science, 277, 370-372.
3. Antonsson B, Montessuit S, Sanchez B and Martinou JC. (2001). J. Biol. Chem., 276, 11615-11623.
4. Apte SS, Mattei MG and Olsen BR. (1995). Genomics, 26, 592-594.
5. Ban J, Eckhart L, Weninger W, Mildner M and Tschachler E. (1998). Biochem. Biophys. Res. Commun., 248, 147-152.
6. Beere HM, Wolf BB, Cain K, Mosser DD, Mahboubi A, Kuwana T, Tailor P, Morimoto RI, Cohen GM and Green DR. (2000). Nat. Cell. Biol., 2, 469-475.
7. Bernardi P, Broekemeier KM and Pfeiffer DR. (1994). J. Bioenerg. Biomembr., 26, 509-517.
8. Bertrand R, Sarang M, Jenkin J, Kerrigan D and Pommier Y. (1991). Cancer Res., 51, 6280-6285.
9. Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nunez G and Thompson CB. (1993). Cell, 74, 597-608.
10. Borner C, Martinou I, Mattmann C, Irmler M, Schaerer E, Martinou JC and Tschopp J. (1994). J. Cell. Biol., 126, 1059-1068.
11. Bottero V, Rossi F, Samson M, Mari M, Hofman P and Peyron JF. (2001). J. Biol. Chem., 276, 21317-21324.
12. Bruey JM, Ducasse C, Bonniaud P, Ravagnan L, Susin SA, Diaz-Latoud C, Gurbuxani S, Arrigo AP, Kroemer G, Solary E and Garrido C. (2000). Nat. Cell. Biol., 2, 645-652.
13. Cain K, Brown DG, Langlais C and Cohen GM. (1999). J. Biol. Chem., 274, 22686-22692.
14. Chao DT and Korsmeyer SJ. (1998). Annu. Rev. Immmol., 16, 395-419.
15. Chaudhary D, Orourke K, Chinnaiyan AM and Dixit VM. (1998). J. Biol. Chem., 273, 17708-17712.
16. Cheng EH-YA, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T and Korsmeyer SJ. (2001). Mol. Cell, 8, 705-711.
17. Chinnaiyan AM, Orourke K, Lane BR and Dixit VM. (1997). Science, 275, 1122-1126.
18. Conus S, Rosse T and Borner C. (2000). Cell. Death Differ., 7, 947-954.
19. de Moissac D, Zheng H and Kirshenbaum LA. (1999). J. Biol. Chem., 274, 29505-29509.
20. Droin N, Beauchemin M, Solary E and Bertrand R. (2000). Cancer Res., 60, 7039-7047.
21. Du C, Fang M, Li Y, Li L and Wang X. (2000). Cell, 102, 33-42.
22. Eskes R, Desagher S, Antonsson B and Martinou JC. (2000). Mol. Cell. Biol., 20, 929-935.
23. Franke TF and Cantley LC. (1997). Nature, 390, 116-117.
24. Garrido C, Bruey JM, Fromentin A, Hammann A, Arrigo AP and Solary E. (1999). FASEB J., 13, 2061-2070.
25. Goping IS, Gross A, Lavoie JN, Nguyen M, Jemmerson R, Roth K, Korsmeyer SJ and Shore GC. (1998). J. Cell. Biol., 143, 207-215.
26. Griffiths GJ, Dubrez L, Morgan CP, Jones NA, Whitehouse J, Corfe BM, Dive C and Hickman JA. (1999). J. Cell. Biol., 144, 903-914.
27. Gross A, Jockel J, Wei MC and Korsmeyer SJ. (1998). EMBO J., 17, 3878-3885.
28. Guo B, Godzik A and Reed JC. (2001). J. Biol. Chem., 276, 2780-2785.
29. Hanada M, Aime-Sempe C, Sato T and Reed JC. (1995). J. Biol. Chem., 270, 11962-11969.
30. Haraguchi M, Torii S, Matsuzawa S, Xie Z, Kitada S, Krajewski S, Yoshida H, Mak TW and Reed JC. (2000). J. Exp. Med., 191, 1709-1720.
31. Hausmann G, O'Reilly LA, van Driel R, Beaumont JG, Strasser A, Adams JM and Huang DC. (2000). J. Cell. Biol., 149, 623-634.
32. He HL, Hershberger PA and McCarthy SA. (1998). J. Immunol., 161, 1169-1175.
33. Hsu SY and Hsueh AJW. (1998). J. Biol. Chem., 273, 30139-30146.
34. Hsu YT, Wolter KG and Youle RJ. (1997). Proc. Natl. Acad. Sci. USA, 94, 3668-3672.
35. Hu YM, Benedict MA, Wu DY, Inohara N and Nunez G. (1998). Proc. Natl. Acad. Sci. USA, 95, 4386-4391.
36. Huang DCS, Adams JM and Cory S. (1998). EMBO J., 17, 1029-1039.
37. Hunter JJ, Bond BL and Parslow TG. (1996). Mol. Cell. Biol., 16, 877-883.
38. Inohara N, Gourley TS, Carrio R, Muniz M, Merino J, Garcia L, Koseki T, Hu YM, Chen S and Nunez G. (1998). J. Biol. Chem., 273, 32479-32486.
39. Jia L, Patwari Y, Srinivasula SM, Newland AC, Fernandes-Alnemri T, Alnemri ES and Kelsey SM. (2001). Oncogene, 20, 4817-4826.
40. Kluck RM, Bossywetzel E, Green DR and Newmeyer DD. (1997a). Science, 275, 1132-1136.
41. Kluck RM, Martin SJ, Hoffman BM, Zhou JS, Green DR and Newmeyer DD. (1997b). EMBO J., 16, 4639-4649.
42. Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ and Schlesinger PH. (2000). Cell. Death Differ., 7, 1166-1173.
43. Kroemer G. (1997). Nat. Med., 3, 614-620.
44. Kroemer G and Reed JC. (2000). Nat. Med., 6, 513-519.
45. Li HL, Zhu H, Xu CJ and Yuan JY. (1998). Cell, 94, 491-501.
46. Li LY, Luo X and Wang X. (2001). Nature, 412, 95-99.
47. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES and Wang X. (1997). Cell, 91, 479-489.
48. Lindsten T, Ross AJ, King A, Zong W, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, Ma A, Golden JA, Evan G, Korsmeyer SJ, MacGregor GR and Thompson CB. (2000). Mol. Cell., 6, 1389-1399.
49. Luo X, Budihardjo I, Zou H, Slaughter C and Wang XD. (1998). Cell, 94, 481-490.
50. Makin GW, Corfe BM, Griffiths GJ, Thistlethwaite A, Hickman JA and Dive C. (2001). EMBO J., 20, 6306-6315.
51. Marzo I, Brenner C, Zamzami N, Jurgensmeier JM, Susin SA, Vieira HLA, Prevost MC, Xie ZH, Matsuyama S, Reed JC and Kroemer G. (1998). Science, 281, 2027-2031.
52. Mikhailov V, Mikhailova M, Pulkrabek DJ, Dong Z, Venkatachalam MA and Saikumar P. (2001). J. Biol. Chem., 276, 18361-18374.
53. Minn AJ, Velez P, Schendel SL, Liang H, Muchmore SW, Fesik SW, Fill M and Thompson CB. (1997). Nature, 385, 353-357.
54. Moriishi K, Huang DC, Cory S and Adams JM. (1999). Proc. Natl. Acad. Sci. USA, 96, 9683-9688.
55. Muchmore SW, Sattler M, Liang H, Meadows RP, Harlan JE, Yoon HS, Nettesheim D, Chang BS, Thompson CB, Wong SL, Ng SC and Fesik SW. (1996). Nature, 381, 335-341.
56. Nechushtan A, Smith CL, Hsu YT and Youle RJ. (1999). EMBO J., 18, 2330-2341.
57. Nechushtan A, Smith CL, Lamensdorf I, Yoon SH and Youle RJ. (2001). J. Cell. Biol., 153, 1265-1276.
58. Newmeyer DD, Bossy-Wetzel E, Kluck RM, Wolf BB, Beere HM and Green DR. (2000). Cell. Death Differ., 7, 402-407.
59. O'Connor L, Strasser A, Oreilly LA, Hausmann G, Adams JM, Cory S and Huang DCS. (1998). EMBO J., 17, 384-395.
60. Oltvai ZN, Milliman CL and Korsmeyer SJ. (1993). Cell, 74, 609-619.
61. Pan GH, Orourke K and Dixit VM. (1998). J. Biol. Chem., 273, 5841-5845.
62. Parrish J, Li L, Klotz K, Ledwich D, Wang X and Xue D. (2001). Nature, 412, 90-94.
63. Pavlov EV, Priault M, Pietkiewicz D, Cheng EH, Antonsson B, Manon S, Korsmeyer SJ, Mannella CA and Kinnally KW. (2001). J. Cell. Biol., 155, 725-732.
64. Qin H, Srinivasula SM, Wu G, Fernandes-Alnemri T, Alnemri ES and Shi Y. (1999). Nature, 399, 549-557.
65. Reed JC. (1997). Nature, 387, 773-776.
66. Saleh A, Srinivasula SM, Balkir L, Robbins PD and Alnemri ES. (2000). Nat. Cell. Biol., 2, 476-483.
67. Schendel SL, Xie ZH, Montal MO, Matsuyama S, Montal M and Reed JC. (1997). Proc. Natl. Acad. Sci. USA, 94, 5113-5118.
68. Schmitt E, Cimoli G, Steyaert A and Bertrand R. (1998a). Exp. Cell. Res., 240, 107-121.
69. Schmitt E, Paquet C, Beauchemin M, Dever-Bertrand J and Bertrand R. (2000). Biochem. Biophys. Res. Commun., 270, 868-879.
70. Schmitt E, Steyaert A, Cimoli G and Bertrand R. (1998b). Cell. Death Differ., 5, 506-516.
71. Seshagiri S and Miller LK. (1997). Curr. Biol., 7, 455-460.
72. Shi B, Triebe D, Kajiji S, Iwata KK, Bruskin A and Mahajna J. (1999). Biochem. Biophys. Res. Commun., 254, 779-785.
73. Shibasaki F, Kondo E, Akagi T and McKeon F. (1997). Nature, 386, 728-731.
74. Shimizu S, Konishi A, Kodama T and Tsujimoto Y. (2000). Proc. Natl. Acad. Sci. USA, 97, 3100-3105.
75. Shimizu S, Narita M and Tsujimoto Y. (1999). Nature, 399, 483-487.
76. Shimizu S and Tsujimoto Y. (2000). Proc. Natl. Acad. Sci. USA, 97, 577-582.
77. Song QZ, Kuang YP, Dixit VM and Vincenz C. (1999). EMBO J., 18, 167-178.
78. Spector MS, Desnoyers S, Hoeppner DJ and Hengartner MO. (1997). Nature, 385, 653-656.
79. Srinivasula SM, Ahmad M, Fernandes-Alnemri T and Alnemri ES. (1998). Mol. Cell., 1, 949-957.
80. Susin SA, Lorenzo HK, Zamzami N, Marzo I, Brenner C, Larochette N, Prevost MC, Alzari PM and Kroemer G. (1999a). J. Exp. Med., 189, 381-393.
81. Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, Mangion J, Jacotot E, Costantini P, Loeffler M, Larochette N, Goodlett DR, Aebersold R, Siderovski DP, Penninger JM and Kroemer G. (1999b). Nature, 397, 441-446.
82. Susin SA, Zamzami N, Castedo M, Hirsch T, Marchetti P, Macho A, Daugas E, Geuskens M and Kroemer G. (1996). J. Exp. Med., 184, 1331-1341.
83. Suzuki Y, Imai Y, Nakayama H, Takahashi K, Takio K and Takahashi R. (2001). Mol. Cell., 8, 613-621.
84. Tsujimoto Y and Croce CM. (1986). Proc. Natl. Acad. Sci. USA, 83, 5214-5218.
85. U M Miyashita T, Shikama Y, Tadokoro K and Yamada M. (2001). FEBS Lett., 509, 135-141.
86. Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE, Moritz RL, Simpson RJ and Vaux DL. (2000). Cell, 102, 43-53.
87. Wang HG, Rapp UR and Reed JC. (1996). Cell, 87, 629-638.
88. Wei MC, Lindsten T, Mootha VK, Weiler S, Gross A, Ashiya M, Thompson CB and Korsmeyer SJ. (2000). Genes Dev., 14, 2060-2071.
89. Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB and Korsmeyer SJ. (2001). Science, 292, 727-730.
90. Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG and Youle RJ. (1997). J. Cell. Biol., 139, 1281-1292.
91. Wu DY, Wallen HD, Inohara N and Nunez G. (1997a). J. Biol. Chem., 272, 21449-21454.
92. Wu DY, Wallen HD and Nunez G. (1997b). Science, 275, 1126-1129.
93. Yang E and Korsmeyer SJ. (1996). Blood, 88, 386-401.
94. Yang J, Liu XS, Bhalla K, Kim CN, Ibrado AM, Cai JY, Peng TI, Jones DP and Wang XD. (1997a). Science, 275, 1129-1132.
95. Yang XF, Weber GF and Cantor H. (1997b). Immunity, 7, 629-639.
96. Yin XM, Oltval ZN and Korsmeyer SJ. (1994). Nature, 369, 321-323.
97. Zhang H, Heim J and Meyhack B. (1999). FEBS Lett., 448, 23-27.
98. Zhao Y, Li S, Childs EE, Kuharsky DK and Yin XM. (2001). J. Biol. Chem., 276, 27432-27440.
99. Zhou M, Demo SD, McClure TN, Crea R and Bitler CM. (1998). J. Biol. Chem., 273, 11930-11936.
100. Zhou P, Chou J, Olea RS, Yuan J and Wagner G. (1999). Proc. Natl. Acad. Sci. USA, 96, 11265-11270.
101. Zong WX, Lindsten T, Ross AJ, MacGregor GR and Thompson CB. (2001). Genes Dev., 15, 1481-1486.
102. Zoratti M and Szabo I. (1996). J. Bioenerg. Biomembr., 26, 543-553.
103. Zou H, Henzel WJ, Liu XS, Lutschg A and Wang XD. (1997). Cell, 90, 405-413.