-
1
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry NA and Lazebnik Y (1998) Caspases: enemies within. Science 281: 1312-1316
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
3
-
-
0032409781
-
Bcl-2 family proteins
-
Reed JC (1998) Bcl-2 family proteins. Oncogene 17: 3225-3236
-
(1998)
Oncogene
, vol.17
, pp. 3225-3236
-
-
Reed, J.C.1
-
4
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams JM and Cory S (1998) The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
5
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR and Newmeyer DD (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
6
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng T-I, Jones DP and Wang X (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275: 1129-1132
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.-I.7
Jones, D.P.8
Wang, X.9
-
7
-
-
0033596980
-
An APAF-1. Cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
Zou H, Li Y, Liu X and Wang X (1999) An APAF-1. Cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274: 11549-11556
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11549-11556
-
-
Zou, H.1
Li, Y.2
Liu, X.3
Wang, X.4
-
8
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES and Wang X (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91: 479-489
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
9
-
-
0030745646
-
Apaf-1, a human protein homologous to C. Elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou H, Henzel WJ, Liu X, Lutschg A and Wang X (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90: 405-413
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
10
-
-
0031888955
-
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
-
Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A and Nagata S (1998) A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391: 43-50
-
(1998)
Nature
, vol.391
, pp. 43-50
-
-
Enari, M.1
Sakahira, H.2
Yokoyama, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.6
-
11
-
-
0031889132
-
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
-
Sakahira H, Enari M and Nagata S (1998) Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391: 96-99
-
(1998)
Nature
, vol.391
, pp. 96-99
-
-
Sakahira, H.1
Enari, M.2
Nagata, S.3
-
12
-
-
0030916417
-
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
Liu X, Zou H, Slaughter C and Wang X (1997) DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89: 175-184
-
(1997)
Cell
, vol.89
, pp. 175-184
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
13
-
-
0033119367
-
Genetic control of programmed cell death in the nematode caenorhabditis elegans
-
Horvitz HR (1999) Genetic control of programmed cell death in the nematode Caenorhabditis elegans. Cancer Res. 59: 1701s-1706s
-
(1999)
Cancer Res.
, vol.59
-
-
Horvitz, H.R.1
-
14
-
-
0031731989
-
Genetics of programmed cell death in C. Elegans: Past, present and future
-
Metzstein MM, Stanfield GM and Horvitz HR (1998) Genetics of programmed cell death in C. elegans: past, present and future. Trends Genet. 14:410-416
-
(1998)
Trends Genet.
, vol.14
, pp. 410-416
-
-
Metzstein, M.M.1
Stanfield, G.M.2
Horvitz, H.R.3
-
15
-
-
0032515874
-
Bcl-Xl interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
-
Hu Y, Benedict MA, Wu D, Inohara N and Nunez G (1998) Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc. Natl. Acad. Sci. USA. 95: 4386-4391
-
(1998)
Proc. Natl. Acad. Sci. USA.
, vol.95
, pp. 4386-4391
-
-
Hu, Y.1
Benedict, M.A.2
Wu, D.3
Inohara, N.4
Nunez, G.5
-
16
-
-
0032489390
-
Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex
-
Pan G, O'Rourke K and Dixit VM (1998) Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex. J. Biol. Chem. 273: 5841-5845
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5841-5845
-
-
Pan, G.1
O'Rourke, K.2
Dixit, V.M.3
-
17
-
-
0342978014
-
Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release
-
Li F, Srinivasan A, Wang Y, Armstrong RC, Tomaselli KJ and Fritz LC (1997) Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release. J. Biol. Chem. 272: 30299-30305
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30299-30305
-
-
Li, F.1
Srinivasan, A.2
Wang, Y.3
Armstrong, R.C.4
Tomaselli, K.J.5
Fritz, L.C.6
-
18
-
-
0031845008
-
Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2
-
Brustugun OT, Fladmark KE, So DS, Orrenius S and Zhivotovsky B (1998) Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2. Cell Death Differ. 5: 660-668
-
(1998)
Cell Death Differ.
, vol.5
, pp. 660-668
-
-
Brustugun, O.T.1
Fladmark, K.E.2
So, D.S.3
Orrenius, S.4
Zhivotovsky, B.5
-
19
-
-
0032576692
-
Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c
-
Rosse T, Olivier R, Monney L, Rager M, Conus S, Fellay I, Jansen B and Borner C (1998) Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c. Nature 391: 496-499
-
(1998)
Nature
, vol.391
, pp. 496-499
-
-
Rosse, T.1
Olivier, R.2
Monney, L.3
Rager, M.4
Conus, S.5
Fellay, I.6
Jansen, B.7
Borner, C.8
-
20
-
-
0033545382
-
Bcl-2 regulates amplification of caspase activation by cytochrome c
-
Cosulich SC, Savory PJ and Clarke PR (1999) Bcl-2 regulates amplification of caspase activation by cytochrome c. Curr. Biol. 9: 147-150
-
(1999)
Curr. Biol.
, vol.9
, pp. 147-150
-
-
Cosulich, S.C.1
Savory, P.J.2
Clarke, P.R.3
-
21
-
-
0031961994
-
Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c
-
Duckett CS, Li F, Wang Y, Tomaselli KJ, Thompson CB and Armstrong RC (1998) Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c. Mol. Cell. Biol. 18: 608-615
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 608-615
-
-
Duckett, C.S.1
Li, F.2
Wang, Y.3
Tomaselli, K.J.4
Thompson, C.B.5
Armstrong, R.C.6
-
22
-
-
0033580901
-
Caspases induce cytochrome c release from mitochondria by activating cytosolic factors
-
In press
-
Bossy-Wetzel E and Green DR (1999) Caspases induce cytochrome c release from mitochondria by activating cytosolic factors. J. Biol. Chem. 274: In press.
-
(1999)
J. Biol. Chem.
, vol.274
-
-
Bossy-Wetzel, E.1
Green, D.R.2
-
23
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H, Zhu H, Xu CJ and Yuan J (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94: 491-501
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
24
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Bucihardjo I, Zou H, Slaughter C and Wang X (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94: 481-490
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Bucihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
26
-
-
0028019746
-
Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirements for an organelle fraction enriched in mitochondria
-
Newmeyer DD, Farschon DM and Reed JC (1994) Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirements for an organelle fraction enriched in mitochondria. Cell 79: 353-364
-
(1994)
Cell
, vol.79
, pp. 353-364
-
-
Newmeyer, D.D.1
Farschon, D.M.2
Reed, J.C.3
-
27
-
-
0030741528
-
Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system
-
Kluck RM, Martin SJ, Hoffman BM, Zhou JS, Green DR and Newmeyer DD (1997) Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system. EMBO J. 16: 4639-4649
-
(1997)
EMBO J.
, vol.16
, pp. 4639-4649
-
-
Kluck, R.M.1
Martin, S.J.2
Hoffman, B.M.3
Zhou, J.S.4
Green, D.R.5
Newmeyer, D.D.6
-
28
-
-
0031127578
-
CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9
-
James C, Gschmeissner S, Fraser A and Evan GI (1997) CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9. Curr. Biol. 7: 246-252
-
(1997)
Curr. Biol.
, vol.7
, pp. 246-252
-
-
James, C.1
Gschmeissner, S.2
Fraser, A.3
Evan, G.I.4
-
29
-
-
0030826436
-
Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9
-
Wu D, Wallen HD, Inohara N and Nunez G (1997) Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9. J. Biol. Chem. 272: 21449-21454
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21449-21454
-
-
Wu, D.1
Wallen, H.D.2
Inohara, N.3
Nunez, G.4
-
30
-
-
0031034997
-
Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death
-
Chinnaiyan AM, O'Rourke K, Lane BR and Dixit VM (1997) Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science 275: 1122-1126
-
(1997)
Science
, vol.275
, pp. 1122-1126
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Lane, B.R.3
Dixit, V.M.4
-
31
-
-
0033578303
-
Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1
-
Moriishi K, Huang DC, Cory S and Adams JM (1999) Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1. Proc. Natl. Acad. Sci. USA. 96: 9683-9688
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9683-9688
-
-
Moriishi, K.1
Huang, D.C.2
Cory, S.3
Adams, J.M.4
-
32
-
-
0032544449
-
Apaf 1 (CED-4 homolog) regulates programmed cell death in mammalian development
-
Cecconi F, Alvarez-Bolado G, Meyer BI, Roth KA and Gruss P (1998) Apaf 1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 94: 727-737
-
(1998)
Cell
, vol.94
, pp. 727-737
-
-
Cecconi, F.1
Alvarez-Bolado, G.2
Meyer, B.I.3
Roth, K.A.4
Gruss, P.5
-
33
-
-
0032544564
-
Apaf 1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida H, Kong YY, Yoshida R, Ella AJ, Hakem A, Hakem R, Penninger JM and Mak TW (1998) Apaf 1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94: 739-750
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
Ella, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.W.8
-
34
-
-
9844257587
-
Inhibition of Bax channel-forming activity by Bcl-2
-
Antonsson B, Conti F, Ciavatta A, Montessuit S, Lewis S, Martinou I, Bernasconi L, Bernard A, Mermod JJ, Mazzei G, Maundrell K, Gambale F, Sadoul R and Martinou JC (1997) Inhibition of Bax Channel-Forming Activity by Bcl-2. Science 277: 370-372
-
(1997)
Science
, vol.277
, pp. 370-372
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
Montessuit, S.4
Lewis, S.5
Martinou, I.6
Bernasconi, L.7
Bernard, A.8
Mermod, J.J.9
Mazzei, G.10
Maundrell, K.11
Gambale, F.12
Sadoul, R.13
Martinou, J.C.14
-
35
-
-
0031008397
-
Channel formation by antiapoptotic protein Bcl-2
-
Schendel SL, Xie Z, Montal MO, Matsuyama S, Montal M and Reed JC (1997) Channel formation by antiapoptotic protein Bcl-2. Proc. Natl. Acad. Sci. USA. 94: 5113-5118
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5113-5118
-
-
Schendel, S.L.1
Xie, Z.2
Montal, M.O.3
Matsuyama, S.4
Montal, M.5
Reed, J.C.6
-
37
-
-
0032553541
-
Cytoprotection by Bcl-2 requires the pore-forming alpha5 and alpha6 helices
-
Matsuyama S, Schendel SL, Xie Z and Reed JC (1998) Cytoprotection by Bcl-2 requires the pore-forming alpha5 and alpha6 helices. J. Biol. Chem. 273: 30995-31001
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30995-31001
-
-
Matsuyama, S.1
Schendel, S.L.2
Xie, Z.3
Reed, J.C.4
-
38
-
-
0030779846
-
Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2
-
Schlesinger PH, Gross A, Yin XM, Yamamoto K, Saito M, Waksman G and Korsmeyer SJ (1997) Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. Proc. Natl. Acad. Sci. USA. 94: 11357-11362
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11357-11362
-
-
Schlesinger, P.H.1
Gross, A.2
Yin, X.M.3
Yamamoto, K.4
Saito, M.5
Waksman, G.6
Korsmeyer, S.J.7
-
39
-
-
0028149786
-
Checkpoints of dueling dimers foil death wishes
-
Oltvai ZN and Korsmeyer SJ (1994) Checkpoints of dueling dimers foil death wishes. Cell 79: 189-192
-
(1994)
Cell
, vol.79
, pp. 189-192
-
-
Oltvai, Z.N.1
Korsmeyer, S.J.2
-
40
-
-
1842332735
-
Bcl-x(L) forms an ion channel in synthetic lipid membranes
-
Minn AJ, Velez P, Schendel SL, Liang H, Muchmore SW, Fesik SW, Fill M and Thompson CB (1997) Bcl-x(L) forms an ion channel in synthetic lipid membranes. Nature 385: 353-357
-
(1997)
Nature
, vol.385
, pp. 353-357
-
-
Minn, A.J.1
Velez, P.2
Schendel, S.L.3
Liang, H.4
Muchmore, S.W.5
Fesik, S.W.6
Fill, M.7
Thompson, C.B.8
-
41
-
-
0033199115
-
Calpain functions in a caspase-independent manner to promote apoptosis-like events during platelet activation
-
In press
-
Wolf BB, Goldstein JC, Stennicke HR, Beere H, Amarante-Mendes GP, Salvesen GS and Green DR (1999) Calpain functions in a caspase-independent manner to promote apoptosis-like events during platelet activation. Blood. (In press)
-
(1999)
Blood
-
-
Wolf, B.B.1
Goldstein, J.C.2
Stennicke, H.R.3
Beere, H.4
Amarante-Mendes, G.P.5
Salvesen, G.S.6
Green, D.R.7
-
42
-
-
0032472329
-
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
-
Bossy-Wetzel E, Newmeyer DD and Green DR (1998) Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J. 17: 37-49
-
(1998)
EMBO J.
, vol.17
, pp. 37-49
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
-
43
-
-
0028885544
-
Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis
-
Martin SJ, Newmeyer DD, Mathias S, Farschon DM, Wang H-G, Reed JC, Kolesnick RN and Green DR (1995) Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis. EMBO J. 14: 5191-5200
-
(1995)
EMBO J.
, vol.14
, pp. 5191-5200
-
-
Martin, S.J.1
Newmeyer, D.D.2
Mathias, S.3
Farschon, D.M.4
Wang, H.-G.5
Reed, J.C.6
Kolesnick, R.N.7
Green, D.R.8
-
44
-
-
0039416421
-
Analysis of apoptotic events using a cell-free system based on Xenopus laevis eggs
-
Herzenberg LH and LA Blackwell C and Weir DM (eds). Blackwell Scientific
-
Newmeyer DD (1998) Analysis of apoptotic events using a cell-free system based on Xenopus laevis eggs. In: Herzenberg LH and LA Blackwell C and Weir DM (eds). Weir's Handbook of Experimental Immunology, Vol. III. Blackwell Scientific. pp. 127.1-127.6
-
(1998)
Weir's Handbook of Experimental Immunology
, vol.3
, pp. 1271-1276
-
-
Newmeyer, D.D.1
|