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Volumn 13, Issue 14, 1999, Pages 2061-2070

HSP27 inhibits cytochrome C-dependent activation of procaspase-9

Author keywords

Apoptosis; Cell death; Drug resistance; Etoposide; Leukemia

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; CYTOCHROME C; ETOPOSIDE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; IMMUNOGLOBULIN G; PROTEIN BCL 2;

EID: 0032722324     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.13.14.2061     Document Type: Article
Times cited : (452)

References (51)
  • 1
    • 0023272554 scopus 로고
    • Acute myelogenous leukemia: Recent advances in therapy
    • Champlin, R., and Gale, R. P. (1987) Acute myelogenous leukemia: recent advances in therapy. Blood 7, 1551-1562
    • (1987) Blood , vol.7 , pp. 1551-1562
    • Champlin, R.1    Gale, R.P.2
  • 2
    • 0024316466 scopus 로고
    • DNA topoisomerase poisons as antitumor drugs
    • Liu, L. F. (1989) DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 58, 351-375
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 351-375
    • Liu, L.F.1
  • 3
    • 0029036445 scopus 로고
    • The role of cell cycle regulation and apoptosis triggering in determining the sensitivity of leukemic cells to topoisomerase I and II inhibitors
    • Dubrez, L., Goldwasser, F., Genne, P., Pommier, Y., and Solary, E. (1995) The role of cell cycle regulation and apoptosis triggering in determining the sensitivity of leukemic cells to topoisomerase I and II inhibitors. Leukemia 9, 1013-1024
    • (1995) Leukemia , vol.9 , pp. 1013-1024
    • Dubrez, L.1    Goldwasser, F.2    Genne, P.3    Pommier, Y.4    Solary, E.5
  • 5
    • 0029853389 scopus 로고    scopus 로고
    • Pivotal role of a DEVD-sensitive step in etoposide-induced and Fasmediated apoptotic pathways
    • Dubrez, L., Savoy, I., Hamman, A., and Solary, E. (1996) Pivotal role of a DEVD-sensitive step in etoposide-induced and Fasmediated apoptotic pathways. EMBO J. 15, 5504-5514
    • (1996) EMBO J. , vol.15 , pp. 5504-5514
    • Dubrez, L.1    Savoy, I.2    Hamman, A.3    Solary, E.4
  • 6
    • 0027892521 scopus 로고
    • Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair
    • Kamesaki, S., Kamesaki, H., Jorgensen, T. J., Tanizawa, A., Pommier, Y., and Cossman, J. (1993) Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair. Cancer Res. 53, 4251-4256
    • (1993) Cancer Res. , vol.53 , pp. 4251-4256
    • Kamesaki, S.1    Kamesaki, H.2    Jorgensen, T.J.3    Tanizawa, A.4    Pommier, Y.5    Cossman, J.6
  • 7
    • 0031034997 scopus 로고    scopus 로고
    • Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death
    • Chinnaiyan, A. M., O'Rourke, K., Lane, B. R., and Dixit, V. M. (1997) Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science 275, 1122-1129
    • (1997) Science , vol.275 , pp. 1122-1129
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Lane, B.R.3    Dixit, V.M.4
  • 10
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria is blocked
    • Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T. I., Jones, D. P., and Wang, X. (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria is blocked. Science 275, 1129-1132
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4    Ibrado, A.M.5    Cai, J.6    Peng, T.I.7    Jones, D.P.8    Wang, X.9
  • 11
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li, P., Nijhaawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhaawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 12
    • 0030782177 scopus 로고    scopus 로고
    • Cytochrome c. can't live with it - Can't live without it
    • Reed, J. C. (1997) Cytochrome c. can't live with it - can't live without it. Cell 91, 559-562
    • (1997) Cell , vol.91 , pp. 559-562
    • Reed, J.C.1
  • 13
    • 0344730049 scopus 로고    scopus 로고
    • BCR-ABL delays etoposide-induced apoptosis upstream of procaspase-3 activation
    • Dubrez, L., Eymin, B., Sordet, O., Droin, N., Turhan, A., and Solary, E. (1998) BCR-ABL delays etoposide-induced apoptosis upstream of procaspase-3 activation. Blood 91, 2215-2422
    • (1998) Blood , vol.91 , pp. 2215-2422
    • Dubrez, L.1    Eymin, B.2    Sordet, O.3    Droin, N.4    Turhan, A.5    Solary, E.6
  • 14
    • 0030014643 scopus 로고    scopus 로고
    • Small stress proteins as novel regulators of apoptosis
    • Mehlen, P., Schulze-Osthoff, K., and Arrigo, A. P. (1996) Small stress proteins as novel regulators of apoptosis. J. Biol. Chem. 271, 16510-16514
    • (1996) J. Biol. Chem. , vol.271 , pp. 16510-16514
    • Mehlen, P.1    Schulze-Osthoff, K.2    Arrigo, A.P.3
  • 15
    • 0000675009 scopus 로고
    • Heat shock proteins and stress tolerance
    • (Morimoto, R. I., Tissières, A., and Georgopoulos, C., eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
    • Parsell, D. A., and Lindquist, S. (1990) Heat shock proteins and stress tolerance. In The Biology of Heat Shock Proteins and Molecular Chaperones (Morimoto, R. I., Tissières, A., and Georgopoulos, C., eds) pp. 457-494, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
    • (1990) The Biology of Heat Shock Proteins and Molecular Chaperones , pp. 457-494
    • Parsell, D.A.1    Lindquist, S.2
  • 16
    • 0002241311 scopus 로고
    • Expression and function of the low molecular weight heat shock proteins
    • (Morimoto, R. I., Tissières, A., and Georgopoulos, C., eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
    • Arrigo, A. P., and Landry, J. (1994) Expression and function of the low molecular weight heat shock proteins. In Heat Shock Proteins: Structure, Function and Regulation (Morimoto, R. I., Tissières, A., and Georgopoulos, C., eds) pp. 335-373, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
    • (1994) Heat Shock Proteins: Structure, Function and Regulation , pp. 335-373
    • Arrigo, A.P.1    Landry, J.2
  • 17
    • 0343742639 scopus 로고    scopus 로고
    • Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation
    • Ehrnsperger, M., Grabel, S., Gaestel, M., and Buchner, J. (1997) Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation. EMBO J. 16, 221-229
    • (1997) EMBO J. , vol.16 , pp. 221-229
    • Ehrnsperger, M.1    Grabel, S.2    Gaestel, M.3    Buchner, J.4
  • 18
    • 0030069517 scopus 로고    scopus 로고
    • HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress
    • Hout, J., Houle, F., Spitz, D. R., and Landry, J. (1996) HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress. Cancer Res. 56, 273-279
    • (1996) Cancer Res. , vol.56 , pp. 273-279
    • Hout, J.1    Houle, F.2    Spitz, D.R.3    Landry, J.4
  • 19
    • 0029933741 scopus 로고    scopus 로고
    • Human hsp27, Drosophila hsp27 and αB-crystallin expressionmediated increase in glutathione is essential for the protective activity of these proteins against TNFα-induced cell death
    • Mehlen, P., Kretz-Remy, C., Preville, X., and Arrigo, A. P. (1996) Human hsp27, Drosophila hsp27 and αB-crystallin expressionmediated increase in glutathione is essential for the protective activity of these proteins against TNFα-induced cell death. EMBO J. 15, 2695-2706
    • (1996) EMBO J. , vol.15 , pp. 2695-2706
    • Mehlen, P.1    Kretz-Remy, C.2    Preville, X.3    Arrigo, A.P.4
  • 20
    • 0024345716 scopus 로고
    • Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells
    • Landry, J., Chrétien, P., Lambert, H., Hickey, E., and Weber, L. A. (1989) Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells. J. Cell biol. 109, 7-15
    • (1989) J. Cell Biol. , vol.109 , pp. 7-15
    • Landry, J.1    Chrétien, P.2    Lambert, H.3    Hickey, E.4    Weber, L.A.5
  • 21
    • 0025988318 scopus 로고
    • Increased survival after treatments with anticancer agents of Chinese hamster cells expressing the human Mr 27,000 heat shock protein
    • Huot, J., Roy, G., Lambert, H., Chrétien, P., and Landry, J. (1991) Increased survival after treatments with anticancer agents of Chinese hamster cells expressing the human Mr 27,000 heat shock protein. Cancer Res. 51, 5245-5252
    • (1991) Cancer Res. , vol.51 , pp. 5245-5252
    • Huot, J.1    Roy, G.2    Lambert, H.3    Chrétien, P.4    Landry, J.5
  • 22
    • 0027293201 scopus 로고
    • Analysis of the resistance to heat and hydrogen peroxide stresses in COS cells transiently expressing wild type or deletion mutants of the Drosophila 27-kDa heat shock protein
    • Mehlen, P., Briolay, J., Smith, L., Diaz-Latoud, C., Fabre, N., Pauli, D., and Arrigo, A. P. (1993) Analysis of the resistance to heat and hydrogen peroxide stresses in COS cells transiently expressing wild type or deletion mutants of the Drosophila 27-kDa heat shock protein. Eur. J. Biochem. 215, 277-284
    • (1993) Eur. J. Biochem. , vol.215 , pp. 277-284
    • Mehlen, P.1    Briolay, J.2    Smith, L.3    Diaz-Latoud, C.4    Fabre, N.5    Pauli, D.6    Arrigo, A.P.7
  • 23
    • 0027366354 scopus 로고
    • The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines
    • Oesterreich, S., Weng, C. N., Qiu, M., Hilsenbeck, S. G., Osborne, C. K., and Fuqua, S. W. (1993) The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines. Cancer Res. 53, 4443-4448
    • (1993) Cancer Res. , vol.53 , pp. 4443-4448
    • Oesterreich, S.1    Weng, C.N.2    Qiu, M.3    Hilsenbeck, S.G.4    Osborne, C.K.5    Fuqua, S.W.6
  • 24
    • 0029979079 scopus 로고    scopus 로고
    • Inconstant association between hsp27 content and doxorubicin resistance in human colon cancer cells
    • Garrido, C., Mehlen, P., Fromentin, A., Hamman, A., Assem, M., Arrigo, A. P., and Chauffert, B. (1996) Inconstant association between hsp27 content and doxorubicin resistance in human colon cancer cells. Eur. J. Biochem. 237, 653-659
    • (1996) Eur. J. Biochem. , vol.237 , pp. 653-659
    • Garrido, C.1    Mehlen, P.2    Fromentin, A.3    Hamman, A.4    Assem, M.5    Arrigo, A.P.6    Chauffert, B.7
  • 25
    • 0030785821 scopus 로고    scopus 로고
    • Hsp27 as a mediator of confluence-dependent resistance to cell death induce by anticancer drugs
    • Garrido, C., Ottavi, P., Fromentin, A., Hammann, A., Arrigo, A. P., Chauffert, B., and Mehlen, P. (1997) Hsp27 as a mediator of confluence-dependent resistance to cell death induce by anticancer drugs. Cancer Res. 57, 2661-2667
    • (1997) Cancer Res. , vol.57 , pp. 2661-2667
    • Garrido, C.1    Ottavi, P.2    Fromentin, A.3    Hammann, A.4    Arrigo, A.P.5    Chauffert, B.6    Mehlen, P.7
  • 27
    • 0028817419 scopus 로고
    • Constitutive expression of human hsp27, Drosophila hsp27, or human aB crystallin confers resistance to TNF- and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts
    • Mehlen, P., Preville, X., Chareyron, P., Briolay, J., Klemenz, R., and Arrigo, A. P. (1995) Constitutive expression of human hsp27, Drosophila hsp27, or human aB crystallin confers resistance to TNF- and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts. J. Immunol 215, 363-374
    • (1995) J. Immunol , vol.215 , pp. 363-374
    • Mehlen, P.1    Preville, X.2    Chareyron, P.3    Briolay, J.4    Klemenz, R.5    Arrigo, A.P.6
  • 28
    • 0029610424 scopus 로고
    • Intracellular reactive oxygen species as apparent modulators of heat shock protein 27 (hsp27) structural organization and phosphorylation in basal and tumor necrosis factor α-treated T47D human carcinoma cells
    • Mehlen, P., Kretz-Remy, C., Briolay, J., Fostan, P., Mirault, M. E., and Arrigo, A. P. (1995) Intracellular reactive oxygen species as apparent modulators of heat shock protein 27 (hsp27) structural organization and phosphorylation in basal and tumor necrosis factor α-treated T47D human carcinoma cells. Biochem. J. 312, 367-375
    • (1995) Biochem. J. , vol.312 , pp. 367-375
    • Mehlen, P.1    Kretz-Remy, C.2    Briolay, J.3    Fostan, P.4    Mirault, M.E.5    Arrigo, A.P.6
  • 29
    • 0025883871 scopus 로고
    • P-glycoprotein expression and in vitro reversion of doxorubicin resistance by verapamil in clinical specimens from acute leukemia and myeloma
    • Solary, E., Bidan, J. M., Chauffert, B., Caillot, D., Mugneret, F., D'Athis, P., Gauville, C., Carli, P. M., and Guy, H. (1991) P-glycoprotein expression and in vitro reversion of doxorubicin resistance by verapamil in clinical specimens from acute leukemia and myeloma. Leukemia 5, 592-597
    • (1991) Leukemia , vol.5 , pp. 592-597
    • Solary, E.1    Bidan, J.M.2    Chauffert, B.3    Caillot, D.4    Mugneret, F.5    D'Athis, P.6    Gauville, C.7    Carli, P.M.8    Guy, H.9
  • 31
    • 0343924897 scopus 로고
    • Coinduction of HSP27 phosphorylation and drug resistance in Chinese hamster cells
    • Hout, J., Roy, G., Lambert, H., and Landry, J. (1992) Coinduction of HSP27 phosphorylation and drug resistance in Chinese hamster cells. Int. J. Oncol. 1, 31-36
    • (1992) Int. J. Oncol. , vol.1 , pp. 31-36
    • Hout, J.1    Roy, G.2    Lambert, H.3    Landry, J.4
  • 32
    • 0027989808 scopus 로고
    • Annexin V for flow cytometry detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman, G., Reutelingsperger, C. P. M., Kuijten, G. A. M., Keehnen, R. M. J., Pals, S. T., and Van Oers, M. H. J. (1994) Annexin V for flow cytometry detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84, 1415-1421
    • (1994) Blood , vol.84 , pp. 1415-1421
    • Koopman, G.1    Reutelingsperger, C.P.M.2    Kuijten, G.A.M.3    Keehnen, R.M.J.4    Pals, S.T.5    Van Oers, M.H.J.6
  • 33
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu, X., Kim, C. N., Yang, J., Jemmerson, R., and Wang, X. (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86, 147-157
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 34
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck, R. M., Bossy-Wetzel, E., Green, D. R., and Newmeyer, D. D. (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275, 1132-1136
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 38
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-lβ-converting enzyme, a mammalian homolog of the C. Elegans cell death gene
    • Miura, M., Zhu, H., Rotello, R., Hartwieg, E. A., and Yuan, J. (1993) Induction of apoptosis in fibroblasts by IL-lβ-converting enzyme, a mammalian homolog of the C. elegans cell death gene. Cell 75, 653-660
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hartwieg, E.A.4    Yuan, J.5
  • 42
    • 0030843575 scopus 로고    scopus 로고
    • L inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis
    • L inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis. Cancer Res. 57, 3115-3120
    • (1997) Cancer Res. , vol.57 , pp. 3115-3120
    • Kim, C.N.1    Wang, X.2    Huang, Y.3    Ibrado, A.M.4    Liu, L.5    Fang, G.6    Bhalla, K.7
  • 44
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the Bcl-2 family
    • Reed, J. C. (1997) Double identity for proteins of the Bcl-2 family. Nature (London) 387, 773-776
    • (1997) Nature (London) , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 46
    • 0032544268 scopus 로고    scopus 로고
    • Apoptotic pathways: The roads to ruin
    • Green, D. R. (1998) Apoptotic pathways: the roads to ruin. Cell 94, 695
    • (1998) Cell , vol.94 , pp. 695
    • Green, D.R.1
  • 47
    • 0007404243 scopus 로고    scopus 로고
    • Large unphosphorylated aggregates as the active form of hsp27 which controls intracellular reactive oxygen species and glutathione levels and generates a protection against TNFa in NIH-3T3-ras cells
    • Mehlen, P., Hickey, E., Weber, L. A., and Arrigo, A. P. (1997) Large unphosphorylated aggregates as the active form of hsp27 which controls intracellular reactive oxygen species and glutathione levels and generates a protection against TNFa in NIH-3T3-ras cells. Biochem. Biophys. Res. Commun. 241, 187-192
    • (1997) Biochem. Biophys. Res. Commun. , vol.241 , pp. 187-192
    • Mehlen, P.1    Hickey, E.2    Weber, L.A.3    Arrigo, A.P.4
  • 48
    • 0039171658 scopus 로고    scopus 로고
    • Analysis of the role of hsp25 phosphorylation reveals the importance of the oligomerization state of this small heat shock protein in its protective function against TNFalpha- and hydrogen peroxide-induced cell death
    • Preville, X., Schultz, H., Knauf, U., Gaestel, M., and Arrigo, A. P. (1998) Analysis of the role of hsp25 phosphorylation reveals the importance of the oligomerization state of this small heat shock protein in its protective function against TNFalpha- and hydrogen peroxide-induced cell death. J. Biol. Chem. 69, 436-452
    • (1998) J. Biol. Chem. , vol.69 , pp. 436-452
    • Preville, X.1    Schultz, H.2    Knauf, U.3    Gaestel, M.4    Arrigo, A.P.5
  • 49
    • 0026082109 scopus 로고
    • Oestrogen receptor D5 antibody is an independent negative prognostic factor in gastric cancer
    • Harrison, J. D., Jones, J. A., and Ellis, I. O. (1991) Oestrogen receptor D5 antibody is an independent negative prognostic factor in gastric cancer. Br. J. Surg. 78, 334-336
    • (1991) Br. J. Surg. , vol.78 , pp. 334-336
    • Harrison, J.D.1    Jones, J.A.2    Ellis, I.O.3
  • 51
    • 0028273481 scopus 로고
    • A 27 kDa heat shock protein that has anomalous prognostic powers in early and advanced breast cancer
    • Love, S., and King, R. J. (1994) A 27 kDa heat shock protein that has anomalous prognostic powers in early and advanced breast cancer. Br. J. Cancer 69, 743-748
    • (1994) Br. J. Cancer , vol.69 , pp. 743-748
    • Love, S.1    King, R.J.2


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