메뉴 건너뛰기




Volumn 5, Issue 6, 1998, Pages 506-516

Bax-α promotes apoptosis induced by cancer chemotherapy and accelerates the activation of caspase 3-like cysteine proteases in p53 double mutant B lymphoma Namalwa cells

Author keywords

Apoptosis; Bax; Cancer chemotherapy; Caspase; Lymphoma

Indexed keywords

ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CISPLATIN; CYSTEINE PROTEINASE; DNA; DNA FRAGMENT; DNA TOPOISOMERASE INHIBITOR; ETOPOSIDE; HYGROMYCIN; MUTANT PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; PROTEIN BAX; PROTEIN P53; VINBLASTINE;

EID: 0031870835     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400376     Document Type: Article
Times cited : (31)

References (104)
  • 1
    • 0028949537 scopus 로고
    • Cloning and expression of four novel isoforms of human tnterleukin-1 beta converting enzyme with different apoptotic activities
    • Alnemri ES, Fernandes-Alnemn Tand Litwack G (1995) Cloning and expression of four novel isoforms of human tnterleukin-1 beta converting enzyme with different apoptotic activities. Journal of Biological Chemistry 270:4313-4317
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 4313-4317
    • Alnemri, E.S.1    Fernandes-Alnemn, T.2    Litwack, G.3
  • 2
    • 0029024368 scopus 로고
    • Mapping of the Human Bax gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, Baxδ
    • Apte SS, Mattei MG and Olsen BR (1995) Mapping of the Human Bax gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, Baxδ. Genomics 26. 529-594
    • (1995) Genomics , vol.26 , pp. 529-594
    • Apte, S.S.1    Mattei, M.G.2    Olsen, B.R.3
  • 3
    • 0028944271 scopus 로고
    • Expression of the bcl-2 gene family in normal and malignant breast tissue: Low bax-alpha expression in tumor cells correlates with resistance towards apoptosis
    • Bargou RC, Daniel PT, Mapara MY, Bommert K, WagenerC, Kallinich B, Royer HD and Dorken B (1995) Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis. International Journal of Cancer 60 854-859
    • (1995) International Journal of Cancer , vol.60 , pp. 854-859
    • Bargou, R.C.1    Daniel, P.T.2    Mapara, M.Y.3    Bommert, K.4    Wagener, C.5    Kallinich, B.6    Royer, H.D.7    Dorken, B.8
  • 4
    • 0025047803 scopus 로고
    • Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hypothermia
    • Barry MA, Behnke CA and Eastman A (1990) Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hypothermia. Biochem Pharmacol. 40: 2353-2362
    • (1990) Biochem Pharmacol. , vol.40 , pp. 2353-2362
    • Barry, M.A.1    Behnke, C.A.2    Eastman, A.3
  • 5
    • 0028954775 scopus 로고
    • Detection of apoptosis-assoctated DNA fragmentation using a rapid and quantitative filter elution assay
    • Bertrand R, Kohn K, Solary E and Pommier Y (1995) Detection of apoptosis-assoctated DNA fragmentation using a rapid and quantitative filter elution assay. Drug Development Res. 34: 138-144
    • (1995) Drug Development Res. , vol.34 , pp. 138-144
    • Bertrand, R.1    Kohn, K.2    Solary, E.3    Pommier, Y.4
  • 6
    • 0026594602 scopus 로고
    • Sequential administration of camptothecin and etoposide circumvents the antagnostic cytotoxicity of simultaneous drug administration in slowly growing human carcinoma. HT-29 cells
    • Bertrand R, O'Connor P, Kerrigan Dand Pommier Y (1992) Sequential administration of camptothecin and etoposide circumvents the antagnostic cytotoxicity of simultaneous drug administration in slowly growing human carcinoma. HT-29 cells. Eur J Cancer 28A: 743-748
    • (1992) Eur J Cancer , vol.28 A , pp. 743-748
    • Bertrand, R.1    O'Connor, P.2    Kerrigan, D.3    Pommier, Y.4
  • 7
    • 0002319031 scopus 로고
    • Assessment of DNA damage in Mammalian cells by DNA filter elution methodology
    • GP Studzinski (Ed.), New York. IRL Press
    • Bertrand R and Pommier Y (1995) Assessment of DNA damage in Mammalian cells by DNA filter elution methodology. In GP Studzinski (Ed.), Cell growth and apoptosis; A practical approach, (Vol. 159, pp. 97-118). New York. IRL Press
    • (1995) Cell Growth and Apoptosis; a Practical Approach , vol.159 , pp. 97-118
    • Bertrand, R.1    Pommier, Y.2
  • 8
    • 0026332184 scopus 로고
    • Differential induction of secondary DNA fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression
    • Bertrand R, Sarang M, Jenkin J, Kerrigan D and Pommier Y (1991) Differential induction of secondary DNA fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression. Cancer Research 51: 6280-6285
    • (1991) Cancer Research , vol.51 , pp. 6280-6285
    • Bertrand, R.1    Sarang, M.2    Jenkin, J.3    Kerrigan, D.4    Pommier, Y.5
  • 9
    • 0027168859 scopus 로고
    • Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors
    • Bertrand R, Solary E, Jenkins J and Pommier Y (1993) Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors. Experimental Cell Research 207:388-397
    • (1993) Experimental Cell Research , vol.207 , pp. 388-397
    • Bertrand, R.1    Solary, E.2    Jenkins, J.3    Pommier, Y.4
  • 11
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of mach, a novel mort1/fadd-interacting protease, in fas/Apo-1- and Tnf receptor-induced cell death
    • Boldin MP, Goncharov TM, Goltsev YV and Wallach D (1996) Involvement of mach, a novel mort1/fadd-interacting protease, in fas/Apo-1- and Tnf receptor-induced cell death Cell 85 803-815
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 14
    • 0028824266 scopus 로고
    • A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow
    • Choi SS, Park IC, Yun JW, Sung YC, Hong SI and Shin HS (1995) A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow. Oncogene 11: 1693-1698
    • (1995) Oncogene , vol.11 , pp. 1693-1698
    • Choi, S.S.1    Park, I.C.2    Yun, J.W.3    Sung, Y.C.4    Hong, S.I.5    Shin, H.S.6
  • 15
    • 0029929672 scopus 로고    scopus 로고
    • Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax-Bcl-2 ratio
    • Chresta CM, Masters JRW and Hickman JA (1996) Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax-Bcl-2 ratio Cancer Research 56. 1834-1841
    • (1996) Cancer Research , vol.56 , pp. 1834-1841
    • Chresta, C.M.1    Masters, J.R.W.2    Hickman, J.A.3
  • 16
    • 0022971142 scopus 로고
    • Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14,18) translocation
    • Clarke ML, Smith SD and Sklar J (1986) Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14,18) translocation. Cell 47: 19-28
    • (1986) Cell , vol.47 , pp. 19-28
    • Clarke, M.L.1    Smith, S.D.2    Sklar, J.3
  • 17
    • 9244246789 scopus 로고    scopus 로고
    • Identification of anovel Bcl-2 related gene, Brag-1, in human glioma
    • Das R, Reddy EP, Chatlerjee D and Andrews DW (1996) Identification of anovel Bcl-2 related gene, Brag-1, in human glioma. Oncogene 12:947-951
    • (1996) Oncogene , vol.12 , pp. 947-951
    • Das, R.1    Reddy, E.P.2    Chatlerjee, D.3    Andrews, D.W.4
  • 18
    • 0028987830 scopus 로고
    • Overexpression of Bcl-xL by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation
    • Datta R, Manome Y, Taneja N, Boise L, Weichselbaum R, Thompson C and Kufe D (1995) Overexpression of Bcl-xL by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation. Cell Growth and Differentiation 6. 363-370
    • (1995) Cell Growth and Differentiation , vol.6 , pp. 363-370
    • Datta, R.1    Manome, Y.2    Taneja, N.3    Boise, L.4    Weichselbaum, R.5    Thompson, C.6    Kufe, D.7
  • 19
    • 0026489662 scopus 로고
    • Apoptotic cell death triggered by camptothecin or teniposide the cell cycle specificity and effects of ionizing radiation
    • Del Bino G, Bruno S, Yi PN and Darzynkiewicz Z (1992) Apoptotic cell death triggered by camptothecin or teniposide The cell cycle specificity and effects of ionizing radiation Cell Proliferation 25: 537-548
    • (1992) Cell Proliferation , vol.25 , pp. 537-548
    • Del Bino, G.1    Bruno, S.2    Yi, P.N.3    Darzynkiewicz, Z.4
  • 20
    • 0030810926 scopus 로고    scopus 로고
    • X-linked iap is a direct inhibitor of cell-death proteases
    • Deveraux QL, Takahashi R, Salvesen GS and Reed JC (1997) X-linked iap is a direct inhibitor of cell-death proteases. Nature 388. 300-304
    • (1997) Nature , vol.388 , pp. 300-304
    • Deveraux, Q.L.1    Takahashi, R.2    Salvesen, G.S.3    Reed, J.C.4
  • 21
    • 0028979439 scopus 로고
    • Bcl-X(L) is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis
    • Dole MG, Jasty R, Cooper MJ, Thompson CB, Nunez G and Castle VP (1995) Bcl-X(L) is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis Cancer Research 55: 2576-2582
    • (1995) Cancer Research , vol.55 , pp. 2576-2582
    • Dole, M.G.1    Jasty, R.2    Cooper, M.J.3    Thompson, C.B.4    Nunez, G.5    Castle, V.P.6
  • 22
    • 0030044324 scopus 로고    scopus 로고
    • Ice-Lap3. a novel mammalian homologue of the caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis
    • Duan HJ, Chinnaiyan AM, Hudson PL, Wing JP, He WW and DiXit V (1996a) Ice-Lap3. a novel mammalian homologue of the caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis. Journal of Biological Chemistry 271: 1621-1625
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 1621-1625
    • Duan, H.J.1    Chinnaiyan, A.M.2    Hudson, P.L.3    Wing, J.P.4    He, W.W.5    DiXit, V.6
  • 30
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme
    • Femandes-Alnemri T, Litwack G and Alnemri ES (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. Journal of Biological Chemistry 269:30761-30764
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 30761-30764
    • Femandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 31
    • 0029025549 scopus 로고
    • Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family
    • Femandes-Alnemri T, Lrtwack G and Alnemri E (1995) Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Research 55:2737-2742
    • (1995) Cancer Research , vol.55 , pp. 2737-2742
    • Femandes-Alnemri, T.1    Lrtwack, G.2    Alnemri, E.3
  • 35
    • 0029941463 scopus 로고    scopus 로고
    • Apoptosis and chemotherapy resistance
    • Hickman JA (1996) Apoptosis and chemotherapy resistance. European Journal of Cancer 32A: 921-926
    • (1996) European Journal of Cancer , vol.32 A , pp. 921-926
    • Hickman, J.A.1
  • 36
    • 0030698810 scopus 로고    scopus 로고
    • The apoptosis-necrosis paradox - Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death
    • Hirsch T, Marchetti P, Susin SA, Dallaporta B, Zamzami N, Marzo I, Geuskens M and Kroemer G (1997) The apoptosis-necrosis paradox - apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene 15: 1573-1581
    • (1997) Oncogene , vol.15 , pp. 1573-1581
    • Hirsch, T.1    Marchetti, P.2    Susin, S.A.3    Dallaporta, B.4    Zamzami, N.5    Marzo, I.6    Geuskens, M.7    Kroemer, G.8
  • 37
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, Schreiber RD and Korsmeyer SJ (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 38
    • 0029328602 scopus 로고
    • BCL-2, a novel regulator of cell death
    • Hockenbery DM (1995) BCL-2, a novel regulator of cell death. Bioessays 17:631-638
    • (1995) Bioessays , vol.17 , pp. 631-638
    • Hockenbery, D.M.1
  • 39
    • 0029561160 scopus 로고
    • Novel hypotheses for the roles of EBNA-1 and BHRF1 in EBV-related cancers
    • Homer D, Lewis M and Farrell PJ (1995) Novel hypotheses for the roles of EBNA-1 and BHRF1 in EBV-related cancers. Intervirology 38. 195-205
    • (1995) Intervirology , vol.38 , pp. 195-205
    • Homer, D.1    Lewis, M.2    Farrell, P.J.3
  • 40
    • 0029658187 scopus 로고    scopus 로고
    • Bcl-X(L) overexpression inhibits taxol-induced yama protease activity and apoptosis
    • Ibrado AM, Huang Y, Fang GF and Bhalla K (1996) Bcl-X(L) overexpression inhibits taxol-induced yama protease activity and apoptosis. Cell Growth and Differentiation 7: 1087-1094
    • (1996) Cell Growth and Differentiation , vol.7 , pp. 1087-1094
    • Ibrado, A.M.1    Huang, Y.2    Fang, G.F.3    Bhalla, K.4
  • 41
    • 0024284750 scopus 로고
    • Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes
    • Jaxel C, Taudou G, Portemer C, Mirarnbeau G, Panijel J and Duguet M (1988) Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes. Biochemistry 27:95-99
    • (1988) Biochemistry , vol.27 , pp. 95-99
    • Jaxel, C.1    Taudou, G.2    Portemer, C.3    Mirarnbeau, G.4    Panijel, J.5    Duguet, M.6
  • 43
    • 0024470862 scopus 로고
    • Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs. a cautionary note
    • Kaufmann SH (1989) Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs. a cautionary note. Cancer Research 49: 5870-5878
    • (1989) Cancer Research , vol.49 , pp. 5870-5878
    • Kaufmann, S.H.1
  • 45
    • 9844226204 scopus 로고    scopus 로고
    • Caspase-dependent apoptosis of Cos-7 cells induced by Baxoverexpression-differential effects of Bcl-2and Bcl-X(L)On Bax-induced caspase activation and apoptosis
    • Kitanaka C, Namiki T, Noguchi K, Mochizuki T, Kagaya S, Chi S, Hayashi A, Asai A, Tsujimoto Y and Kuchino Y (1997) Caspase-dependent apoptosis of Cos-7 cells induced by Baxoverexpression-differential effects of Bcl-2and Bcl-X(L)On Bax-induced caspase activation and apoptosis Oncogene 15: 1763-1772
    • (1997) Oncogene , vol.15 , pp. 1763-1772
    • Kitanaka, C.1    Namiki, T.2    Noguchi, K.3    Mochizuki, T.4    Kagaya, S.5    Chi, S.6    Hayashi, A.7    Asai, A.8    Tsujimoto, Y.9    Kuchino, Y.10
  • 46
    • 0015924847 scopus 로고
    • Relationship between the sensitivity of EBV-carrying lymphoblastoid lines to superinfection and the inducibility of the resident viral genome
    • Klein G and Dombos L (1973) Relationship between the sensitivity of EBV-carrying lymphoblastoid lines to superinfection and the inducibility of the resident viral genome. Int. J. Cancer 11:327
    • (1973) Int. J. Cancer , vol.11 , pp. 327
    • Klein, G.1    Dombos, L.2
  • 48
    • 0026655474 scopus 로고
    • Bcl-2 initiates a new category of oncogenes: Regulators of cell death
    • Korsmeyer SJ (1992) Bcl-2 initiates a new category of oncogenes: Regulators of cell death. Blood 80: 879-886
    • (1992) Blood , vol.80 , pp. 879-886
    • Korsmeyer, S.J.1
  • 49
    • 0028956550 scopus 로고
    • Regulators of cell death
    • Korsmeyer SJ (1995) Regulators of cell death. [Review]. Trends in Genetics 11: 101-105
    • (1995) Trends in Genetics , vol.11 , pp. 101-105
    • Korsmeyer, S.J.1
  • 50
    • 0027480450 scopus 로고
    • MCL1. a gene expressed in programmed myeloid cell differentiation, has sequence similarity to Bcl-2
    • Kozopas KM, Yang T, Buchan HL, Zhou P and Craig RW (1995) MCL1. a gene expressed in programmed myeloid cell differentiation, has sequence similarity to Bcl-2. Proc. Natl. Acad. Sci. USA 90: 3516-3520
    • (1995) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3516-3520
    • Kozopas, K.M.1    Yang, T.2    Buchan, H.L.3    Zhou, P.4    Craig, R.W.5
  • 51
    • 0029045784 scopus 로고
    • Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma
    • Krajewski S, Blomqvist C, Franssila K, Krajewska M, Wasenius VM, Niskanen E, Nordling S and Reed JC (1995) Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma. Cancer Research 55: 4471-4478
    • (1995) Cancer Research , vol.55 , pp. 4471-4478
    • Krajewski, S.1    Blomqvist, C.2    Franssila, K.3    Krajewska, M.4    Wasenius, V.M.5    Niskanen, E.6    Nordling, S.7    Reed, J.C.8
  • 53
    • 0029794385 scopus 로고    scopus 로고
    • The ICE family of cysteine proteases as effectors of cell death
    • Kumar S and Lavin MF (1996) The ICE family of cysteine proteases as effectors of cell death. Cell Death Differ. 3: 255-267
    • (1996) Cell Death Differ. , vol.3 , pp. 255-267
    • Kumar, S.1    Lavin, M.F.2
  • 54
    • 0023867576 scopus 로고
    • Sensitive, high-resolution chromatin and chromosome mapping in situ: Presence and orientation of two closely integrated copies of EBV in a lymphoma cell line
    • Lawrence JB, Villnave CA and Singer RH (1988) Sensitive, high-resolution chromatin and chromosome mapping in situ: presence and orientation of two closely integrated copies of EBV in a lymphoma cell line. Cell 52: 51-61
    • (1988) Cell , vol.52 , pp. 51-61
    • Lawrence, J.B.1    Villnave, C.A.2    Singer, R.H.3
  • 55
  • 56
    • 0027326012 scopus 로고
    • Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2
    • Lin EY, Orlofsky A, Berger MS and Prystowsky MB (1993) Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2 J. Immunol. 151: 1979-1988
    • (1993) J. Immunol. , vol.151 , pp. 1979-1988
    • Lin, E.Y.1    Orlofsky, A.2    Berger, M.S.3    Prystowsky, M.B.4
  • 57
    • 0030044012 scopus 로고    scopus 로고
    • Identification and characterization of Cpp32/2mch2 homolog 1, a novel cysteine protease similar to Cpp32
    • Lippke JA, Gu Y, Sarnecte C, Caron PR and Su MSS (1996) Identification and characterization of Cpp32/2mch2 homolog 1, a novel cysteine protease similar to Cpp32 Journal of Biological Chemistry 271: 1825-1828
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 1825-1828
    • Lippke, J.A.1    Gu, Y.2    Sarnecte, C.3    Caron, P.R.4    Su, M.S.S.5
  • 58
    • 0018087773 scopus 로고
    • Purification of the Epstein-Barr virus-determined nuclear antigen from Epstein-Barr virus-transformed human lymphoid cell lines
    • Luka J, Lindahl T and Klein G (1978) Purification of the Epstein-Barr virus-determined nuclear antigen from Epstein-Barr virus-transformed human lymphoid cell lines. Journal of Virology 27: 604-611
    • (1978) Journal of Virology , vol.27 , pp. 604-611
    • Luka, J.1    Lindahl, T.2    Klein, G.3
  • 59
    • 0021683573 scopus 로고
    • Persistence of the entire Epstein-Barr virus genome integrated into human lymphocyte DNA
    • Matsuo T, Heller M, Petti L. O'Shiro E and Kieff E (1984) Persistence of the entire Epstein-Barr virus genome integrated into human lymphocyte DNA. Science 226: 1322-1325
    • (1984) Science , vol.226 , pp. 1322-1325
    • Matsuo, T.1    Heller, M.2    Petti, L.3    O'Shiro, E.4    Kieff, E.5
  • 60
    • 0029897734 scopus 로고    scopus 로고
    • Apoptosis sensitivity in chronic lymphocytic leukemia is determined by endogenous endonuclease content and relative expression of Bcl-2 and Bax
    • McConkey DJ, Chandra J, Wright S, Plunkett W, McDonnell TJ, Reed JC and Keating M (1996) Apoptosis sensitivity in chronic lymphocytic leukemia is determined by endogenous endonuclease content and relative expression of Bcl-2 and Bax. Journal of Immunology 156: 2624-2630
    • (1996) Journal of Immunology , vol.156 , pp. 2624-2630
    • McConkey, D.J.1    Chandra, J.2    Wright, S.3    Plunkett, W.4    McDonnell, T.J.5    Reed, J.C.6    Keating, M.7
  • 61
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD and Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16: 1215
    • (1988) Nucleic Acids Res. , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 63
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T and Reed JC (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80: 293-299
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 68
    • 0027421045 scopus 로고
    • Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Buricitt's lymphoma cell lines
    • O'Connor PM, Jackman J, Jondle D, Bhatia K, Magrath I and Kohn KW (1993) Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Buricitt's lymphoma cell lines. Cancer Research 53: 4776-4780
    • (1993) Cancer Research , vol.53 , pp. 4776-4780
    • O'Connor, P.M.1    Jackman, J.2    Jondle, D.3    Bhatia, K.4    Magrath, I.5    Kohn, K.W.6
  • 69
    • 0028149786 scopus 로고
    • Checkpoints of dueling dimers foil death wishes
    • Oltvai ZN and Korsmeyer SJ (1994) Checkpoints of dueling dimers foil death wishes. Cell 79: 189-192
    • (1994) Cell , vol.79 , pp. 189-192
    • Oltvai, Z.N.1    Korsmeyer, S.J.2
  • 70
    • 0027166048 scopus 로고
    • Bcl-2 heterodimenzes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL and Korsmeyer SJ (1993) Bcl-2 heterodimenzes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 71
  • 72
    • 0023280501 scopus 로고
    • Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex
    • Pearson GR, Luka J, Petti L, Sample J, Birkenbach M, Braun D and Kieff E (1987) Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex. Virology 160: 151-161
    • (1987) Virology , vol.160 , pp. 151-161
    • Pearson, G.R.1    Luka, J.2    Petti, L.3    Sample, J.4    Birkenbach, M.5    Braun, D.6    Kieff, E.7
  • 73
    • 0000420523 scopus 로고    scopus 로고
    • DNA topoisomerase II inhibitors
    • BA Teicher (Ed.), Totowa, New Jersey Humana Press Inc
    • Pommier Y (1997) DNA topoisomerase II inhibitors. In BA Teicher (Ed.), Cancer Therapeutics: Experimental and Clinical Agents, (pp. 153-174). Totowa, New Jersey Humana Press Inc
    • (1997) Cancer Therapeutics: Experimental and Clinical Agents , pp. 153-174
    • Pommier, Y.1
  • 74
    • 0028782781 scopus 로고
    • Programmed cell death and the control of cell survival. Philosophical Transactions of the Royal Society of London - Senes B
    • Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y and Jacobson MD (1994) Programmed cell death and the control of cell survival. Philosophical Transactions of the Royal Society of London - Senes B. Biological Sciences 345: 265-268
    • (1994) Biological Sciences , vol.345 , pp. 265-268
    • Raff, M.C.1    Barres, B.A.2    Burne, J.F.3    Coles, H.S.4    Ishizaki, Y.5    Jacobson, M.D.6
  • 75
    • 0029558583 scopus 로고
    • Bcl-2 family proteins - Regulators of chemoresistance in cancer
    • Reed JC (1995) Bcl-2 family proteins - regulators of chemoresistance in cancer Toxicology Letters 3: 155-158
    • (1995) Toxicology Letters , vol.3 , pp. 155-158
    • Reed, J.C.1
  • 76
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the Bcl-2 farmly
    • Reed JC (1997) Double identity for proteins of the Bcl-2 farmly. Nature 387:773-776
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 79
    • 0024535280 scopus 로고
    • Two related Epstein-Barr virus membrane proteins are encoded by separate genes
    • Sample J, Liebowitz D and Kieff E (1989) Two related Epstein-Barr virus membrane proteins are encoded by separate genes. Journal of Virology 63: 933-937
    • (1989) Journal of Virology , vol.63 , pp. 933-937
    • Sample, J.1    Liebowitz, D.2    Kieff, E.3
  • 80
    • 0031301839 scopus 로고    scopus 로고
    • The CrmA- and TPCK-sensitive pathways that trigger the oligonucleosome-sized DNA fragmentation in camptothecin-induced apoptosis: Relation to caspase activation and hig molecular weight DNA fragmentation
    • Sane AT, Schmitt E, Steyaert A, Meyer D and Bertrand R (1997) The CrmA- and TPCK-sensitive pathways that trigger the oligonucleosome-sized DNA fragmentation in camptothecin-induced apoptosis: relation to caspase activation and hig molecular weight DNA fragmentation. Biochemical and Cellular Biology 75: 359-368
    • (1997) Biochemical and Cellular Biology , vol.75 , pp. 359-368
    • Sane, A.T.1    Schmitt, E.2    Steyaert, A.3    Meyer, D.4    Bertrand, R.5
  • 81
    • 0024558619 scopus 로고
    • Expression of EBNA-3 family in fresh B lymphocytes infected with Epstein-Barr virus
    • Sawada K, Yamamoto M, Tabata T, Smith M, Tanaka A and Nonoyama M (1989) Expression of EBNA-3 family in fresh B lymphocytes infected with Epstein-Barr virus. Virology 168: 22-30
    • (1989) Virology , vol.168 , pp. 22-30
    • Sawada, K.1    Yamamoto, M.2    Tabata, T.3    Smith, M.4    Tanaka, A.5    Nonoyama, M.6
  • 83
    • 0029984098 scopus 로고    scopus 로고
    • Bcl-2 expression prevents activation of the ice protease cascade
    • Shimizu S, Eguchi Y, Kamiike W, Matsuda H and Tsujimoto Y (1996) Bcl-2 expression prevents activation of the ice protease cascade Oncogene 12 2251-2257
    • (1996) Oncogene , vol.12 , pp. 2251-2257
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, W.3    Matsuda, H.4    Tsujimoto, Y.5
  • 84
    • 0029787506 scopus 로고    scopus 로고
    • Bax can antagonize Bcl-X(L) during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-X(L)
    • Simonian PL, Grillot DAM, Menno R and Nunez G (1996) Bax can antagonize Bcl-X(L) during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-X(L) Journal of Biological Chemistry 271:22764-22772
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 22764-22772
    • Simonian, P.L.1    Grillot, D.A.M.2    Menno, R.3    Nunez, G.4
  • 85
    • 0027403207 scopus 로고
    • Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors
    • Solary E, Bertrand R, Kohn KW and Pommier Y (1993) Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors. Blood 81: 1359-1368
    • (1993) Blood , vol.81 , pp. 1359-1368
    • Solary, E.1    Bertrand, R.2    Kohn, K.W.3    Pommier, Y.4
  • 87
    • 0028979438 scopus 로고
    • Overexpression of Bcl-X(S), sensitizes Mcf-7 cells to chemotherapy-induced apoptosis
    • Sumantran VN, Ealovega MW, Nunez G, Clarke MF and Wicha MS (1995) Overexpression of Bcl-X(S), sensitizes Mcf-7 cells to chemotherapy-induced apoptosis Cancer Research 55: 2507-2510
    • (1995) Cancer Research , vol.55 , pp. 2507-2510
    • Sumantran, V.N.1    Ealovega, M.W.2    Nunez, G.3    Clarke, M.F.4    Wicha, M.S.5
  • 88
    • 0030219848 scopus 로고    scopus 로고
    • Cloning of Cdnas encoding the human Bag 1 protein and localization of the human Bag1 gene to chromosome 9p12
    • Takayama S, Kochel K, Irie S, Inazawa J, Abe J, Sato T, Druck T, Huebner K and Reed JC (1996) Cloning of Cdnas encoding the human Bag 1 protein and localization of the human Bag1 gene to chromosome 9p12. Genomics 35: 494-498
    • (1996) Genomics , vol.35 , pp. 494-498
    • Takayama, S.1    Kochel, K.2    Irie, S.3    Inazawa, J.4    Abe, J.5    Sato, T.6    Druck, T.7    Huebner, K.8    Reed, J.C.9
  • 89
    • 0028847915 scopus 로고
    • Cloning and functional analysis of Bag-1; a novel Bcl-2 binding protein with anti-cell death activity
    • Takayama S, SatoT, Krajewski S, Kochel K, Irie S, Millan JA and JC R (1995) Cloning and functional analysis of Bag-1; a novel Bcl-2 binding protein with anti-cell death activity. Cell 80: 279-284
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    JC, R.7
  • 90
    • 0028990125 scopus 로고
    • Yama/Cpp32-Beta, a mammalian homolog of Ced-3, is a Crma-inhibitable protease that cleaves the death substrate Poly(ADP-ribose) polymerase
    • Tewari M, Quan LT, Orourke K, Desnoyers S, Zeng Z, Beidler DR, Poirier GG, Salvesen GS and Dixit VM (1995) Yama/Cpp32-Beta, a mammalian homolog of Ced-3, is a Crma-inhibitable protease that cleaves the death substrate Poly(ADP-ribose) polymerase. Cell 81:801-809
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    Orourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesen, G.S.8    Dixit, V.M.9
  • 91
    • 0029978058 scopus 로고    scopus 로고
    • Drug-induced apoptosis in B-cell chronic lymphocytic leukemia - Relationship between p53 gene mutation and Bcl-2/Bax proteins in drug resistance
    • Thomas A, Elrouby S, Reed JC, Krajewski S, Silber R, Potmesil M and Newcomb EW (1996) Drug-induced apoptosis in B-cell chronic lymphocytic leukemia - relationship between p53 gene mutation and Bcl-2/Bax proteins in drug resistance. Oncogene 12: 1055-1062
    • (1996) Oncogene , vol.12 , pp. 1055-1062
    • Thomas, A.1    Elrouby, S.2    Reed, J.C.3    Krajewski, S.4    Silber, R.5    Potmesil, M.6    Newcomb, E.W.7
  • 92
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 93
    • 0021679848 scopus 로고
    • Cloning of the chromosome breakpoint of neoplastic B cells with the t(14:18) chromosome translocation
    • Tsujiimoto Y, Finger LR, Yunis J, Nowell PC and Croce CM (1984) Cloning of the chromosome breakpoint of neoplastic B cells with the t(14:18) chromosome translocation. Science 226: 1097-1099
    • (1984) Science , vol.226 , pp. 1097-1099
    • Tsujiimoto, Y.1    Finger, L.R.2    Yunis, J.3    Nowell, P.C.4    Croce, C.M.5
  • 94
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S and Adams JM (1988) Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 355.440-442
    • (1988) Nature , vol.355 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 97
    • 0028168593 scopus 로고
    • Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death
    • Wang L, Miura M, Bergeron L, Zhu H and Yuan J (1994) Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78: 739-750
    • (1994) Cell , vol.78 , pp. 739-750
    • Wang, L.1    Miura, M.2    Bergeron, L.3    Zhu, H.4    Yuan, J.5
  • 99
    • 0029808205 scopus 로고    scopus 로고
    • Identification and characterization of Ich-3, a member of the interleukin-1-beta converting enzyme (Ice)/Ced-3 family and an upstream regulator of Ice
    • Wang SY, Miura M, Jung YK, Zhu H, Gagliardini V, Shi LF, Greenberg AH and Yuan JY (1996) Identification and characterization of Ich-3, a member of the interleukin-1-beta converting enzyme (Ice)/Ced-3 family and an upstream regulator of Ice. Journal of Biological Chemistry 271: 20580-20587
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 20580-20587
    • Wang, S.Y.1    Miura, M.2    Jung, Y.K.3    Zhu, H.4    Gagliardini, V.5    Shi, L.F.6    Greenberg, A.H.7    Yuan, J.Y.8
  • 102
    • 0029906828 scopus 로고    scopus 로고
    • Bax-induced cell death may not require interleukin 1-beta-converting enzyme-like proteases
    • Xiang JL, Chao DT and Korsmeyer SJ (1996) Bax-induced cell death may not require interleukin 1-beta-converting enzyme-like proteases. Proc. Natl.Acad Sci. USA 93: 14559-14563
    • (1996) Proc. Natl.Acad Sci. USA , vol.93 , pp. 14559-14563
    • Xiang, J.L.1    Chao, D.T.2    Korsmeyer, S.J.3
  • 103
    • 0028809209 scopus 로고
    • Bad. a heterodimeric partner for Bel-XL and Bcl-2, displaces Bax and promotes cell death
    • Yang E, Zha J, Jockel J, Boise LH, Thompson CB and Korsmeyer SJ (1995) Bad. a heterodimeric partner for Bel-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80: 285-291
    • (1995) Cell , vol.80 , pp. 285-291
    • Yang, E.1    Zha, J.2    Jockel, J.3    Boise, L.H.4    Thompson, C.B.5    Korsmeyer, S.J.6
  • 104
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similarto mammalian interleukine-1B-converting enzyme
    • Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz R (1993) The C. elegans cell death gene ced-3 encodes a protein similarto mammalian interleukine-1B-converting enzyme. Cell 75: 641-652
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.