Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

EMBO Journal

Volumn 17, Issue 14, 1998, Pages 3878-3885

  Gross, Atan ^a   Jockel, Jennifer ^a   Wei, Michael C ^a   Korsmeyer, Stanley J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; BAX; Caspases; Dimerization; Mitochondria

Indexed keywords

CASPASE; CELL ENZYME; CYTOCHROME C; INTERLEUKIN 3; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL KILLING; CHIMERA; CONTROLLED STUDY; CROSS LINKING; DIMERIZATION; ENZYME ACTIVATION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASE 3; CASPASE 9; CASPASES; CELL LINE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; CYTOSOL; DIMERIZATION; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-3; LIGANDS; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RECOMBINANT FUSION PROTEINS; TACROLIMUS;

EID: 0032528118     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.14.3878     Document Type: Article

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