메뉴 건너뛰기




Volumn 163, Issue 6, 2003, Pages 2247-2257

Interference with Transforming Growth Factor-β/Smad3 Signaling Results in Accelerated Healing of Wounds in Previously Irradiated Skin

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 10744233540     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63582-1     Document Type: Article
Times cited : (149)

References (42)
  • 2
    • 0030934532 scopus 로고    scopus 로고
    • Wound healing-aiming for perfect skin regeneration
    • Martin P: Wound healing-aiming for perfect skin regeneration. Science 1997, 276:75-81
    • (1997) Science , vol.276 , pp. 75-81
    • Martin, P.1
  • 3
    • 0033517356 scopus 로고    scopus 로고
    • Cutaneous wound healing
    • Singer AJ, Clark RA: Cutaneous wound healing. N Engl J Med 1999, 341:738-746
    • (1999) N Engl J Med , vol.341 , pp. 738-746
    • Singer, A.J.1    Clark, R.A.2
  • 4
    • 0031931615 scopus 로고    scopus 로고
    • Enhanced expression of transforming growth factor-beta type I and type II receptors in wound granulation tissue and hypertrophic scar
    • Schmid P, Itin P, Cherry G, Bi C, Cox DA: Enhanced expression of transforming growth factor-beta type I and type II receptors in wound granulation tissue and hypertrophic scar. Am J Pathol 1998, 152:485-493
    • (1998) Am J Pathol , vol.152 , pp. 485-493
    • Schmid, P.1    Itin, P.2    Cherry, G.3    Bi, C.4    Cox, D.A.5
  • 5
    • 0029875396 scopus 로고    scopus 로고
    • Transforming growth factors beta1, beta2, and beta3 and their receptors are differentially regulated during normal and impaired wound healing
    • Frank S, Madlener M, Werner S: Transforming growth factors beta1, beta2, and beta3 and their receptors are differentially regulated during normal and impaired wound healing. J Biol Chem 1996, 271: 10188-10193
    • (1996) J Biol Chem , vol.271 , pp. 10188-10193
    • Frank, S.1    Madlener, M.2    Werner, S.3
  • 6
    • 37049184914 scopus 로고
    • Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo
    • Sporn MB, Roberts AB, Shull JH, Smith JM, Ward JM, Sodek J: Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo. Science 1983, 219:1329-1331
    • (1983) Science , vol.219 , pp. 1329-1331
    • Sporn, M.B.1    Roberts, A.B.2    Shull, J.H.3    Smith, J.M.4    Ward, J.M.5    Sodek, J.6
  • 7
    • 0025942430 scopus 로고
    • TGF-beta 1 accelerates wound healing: Reversal of steroid-impaired healing in rats and rabbits
    • Beck LS, DeGuzman L, Lee WP, Xu Y, McFatridge LA, Amento EP: TGF-beta 1 accelerates wound healing: reversal of steroid-impaired healing in rats and rabbits. Growth Factors 1991, 5:295-304
    • (1991) Growth Factors , vol.5 , pp. 295-304
    • Beck, L.S.1    DeGuzman, L.2    Lee, W.P.3    Xu, Y.4    McFatridge, L.A.5    Amento, E.P.6
  • 8
    • 0027141118 scopus 로고
    • One systemic administration of transforming growth factor-beta 1 reverses age- or glucocorticoid-impaired wound healing
    • Beck LS, DeGuzman L, Lee WP, Xu Y, Siegel MW, Amento EP: One systemic administration of transforming growth factor-beta 1 reverses age- or glucocorticoid-impaired wound healing. J Clin Invest 1993, 92:2841-2849
    • (1993) J Clin Invest , vol.92 , pp. 2841-2849
    • Beck, L.S.1    DeGuzman, L.2    Lee, W.P.3    Xu, Y.4    Siegel, M.W.5    Amento, E.P.6
  • 9
    • 0034644472 scopus 로고    scopus 로고
    • TGFbeta signaling in growth control, cancer, and heritable disorders
    • Massague J, Blain SW, Lo RS: TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 2000, 103:295-309
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 12
    • 0030948488 scopus 로고    scopus 로고
    • Wound healing following radiation therapy: A review
    • Tibbs MK: Wound healing following radiation therapy: a review. Radiother Oncol 1997, 42:99-106
    • (1997) Radiother Oncol , vol.42 , pp. 99-106
    • Tibbs, M.K.1
  • 14
    • 0027855061 scopus 로고
    • Collagen gene expression and wound strength in normal and radiation-impaired wounds. A model of radiation-impaired wound healing
    • Bernstein EF, Salomon GD, Harisiadis L, Talbot T, Harrington F, Russo A, Uitto J: Collagen gene expression and wound strength in normal and radiation-impaired wounds. A model of radiation-impaired wound healing. J Dermatol Surg Oncol 1993, 19:564-570
    • (1993) J Dermatol Surg Oncol , vol.19 , pp. 564-570
    • Bernstein, E.F.1    Salomon, G.D.2    Harisiadis, L.3    Talbot, T.4    Harrington, F.5    Russo, A.6    Uitto, J.7
  • 17
    • 0023808340 scopus 로고
    • Assay of radiation effects in mouse skin as expressed in wound healing
    • Gorodetsky R, McBride WH, Withers HR: Assay of radiation effects in mouse skin as expressed in wound healing. Radiat Res 1988, 116: 135-144
    • (1988) Radiat Res , vol.116 , pp. 135-144
    • Gorodetsky, R.1    McBride, W.H.2    Withers, H.R.3
  • 19
    • 0028886352 scopus 로고
    • Expression of transforming growth factor-beta 1 in mouse skin during the acute phase of radiation damage
    • Randall K, Coggle JE: Expression of transforming growth factor-beta 1 in mouse skin during the acute phase of radiation damage. Int J Radiat Biol 1995, 68:301-309
    • (1995) Int J Radiat Biol , vol.68 , pp. 301-309
    • Randall, K.1    Coggle, J.E.2
  • 20
    • 0029838436 scopus 로고    scopus 로고
    • Long-term expression of transforming growth factor TGF beta 1 in mouse skin after localized beta-irradiation
    • Randall K, Coggle JE: Long-term expression of transforming growth factor TGF beta 1 in mouse skin after localized beta-irradiation. Int J Radiat Biol 1996, 70:351-360
    • (1996) Int J Radiat Biol , vol.70 , pp. 351-360
    • Randall, K.1    Coggle, J.E.2
  • 21
    • 0034178260 scopus 로고    scopus 로고
    • TGF-beta1 and radiation fibrosis: A master switch and a specific therapeutic target?
    • Martin M, Lefaix J, Delanian S: TGF-beta1 and radiation fibrosis: a master switch and a specific therapeutic target? Int J Radiat Oncol Biol Phys 2000, 47:277-290
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 277-290
    • Martin, M.1    Lefaix, J.2    Delanian, S.3
  • 22
    • 0027256061 scopus 로고
    • Temporal modulation of TGF-beta 1 and beta-actin gene expression in pig skin and muscular fibrosis after ionizing radiation
    • Martin M, Lefaix JL, Pinton P, Crechet F, Daburon F: Temporal modulation of TGF-beta 1 and beta-actin gene expression in pig skin and muscular fibrosis after ionizing radiation. Radiat Res 1993, 134:63-70
    • (1993) Radiat Res , vol.134 , pp. 63-70
    • Martin, M.1    Lefaix, J.L.2    Pinton, P.3    Crechet, F.4    Daburon, F.5
  • 23
    • 0033104503 scopus 로고    scopus 로고
    • Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta
    • Yang X, Letterio JJ, Lechleider RJ, Chen L, Hayman R, Gu H, Roberts AB, Deng C: Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. EMBO J 1999, 18:1280-1291
    • (1999) EMBO J , vol.18 , pp. 1280-1291
    • Yang, X.1    Letterio, J.J.2    Lechleider, R.J.3    Chen, L.4    Hayman, R.5    Gu, H.6    Roberts, A.B.7    Deng, C.8
  • 24
    • 0032873465 scopus 로고    scopus 로고
    • Connective tissue growth factor mediates transforming growth factor-beta-induced collagen synthesis; down-regulation by cAMP
    • Duncan MR, Frazier KS, Abramson S, Williams S, Klapper H, Huang X, Grotendorst GR: Connective tissue growth factor mediates transforming growth factor-beta-induced collagen synthesis; down-regulation by cAMP. EMBO J 1999, 13:1774-1786
    • (1999) EMBO J , vol.13 , pp. 1774-1786
    • Duncan, M.R.1    Frazier, K.S.2    Abramson, S.3    Williams, S.4    Klapper, H.5    Huang, X.6    Grotendorst, G.R.7
  • 27
    • 0037183986 scopus 로고    scopus 로고
    • Vascular smooth muscle alpha-actin gene transcription during myofibroblast differentiation requires Sp1/β protein binding proximal to the MCAT enhancer
    • Cogan JG, Subramanian SV, Polikandriotis JA, Kelm Jr RJ, Strauch AR: Vascular smooth muscle alpha-actin gene transcription during myofibroblast differentiation requires Sp1/β protein binding proximal to the MCAT enhancer. J Biol Chem 2002, 277:36433-36442
    • (2002) J Biol Chem , vol.277 , pp. 36433-36442
    • Cogan, J.G.1    Subramanian, S.V.2    Polikandriotis, J.A.3    Kelm Jr., R.J.4    Strauch, A.R.5
  • 28
    • 0023104031 scopus 로고
    • Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta
    • Postlethwaite AE, Kesi J, Moses HL, Kang AH: Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta. J Exp Med 1987, 165:251-256
    • (1987) J Exp Med , vol.165 , pp. 251-256
    • Postlethwaite, A.E.1    Kesi, J.2    Moses, H.L.3    Kang, A.H.4
  • 30
    • 0031225015 scopus 로고    scopus 로고
    • Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts
    • Grotendorst GR: Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev 1997, 8:171-179
    • (1997) Cytokine Growth Factor Rev , vol.8 , pp. 171-179
    • Grotendorst, G.R.1
  • 31
    • 0029549748 scopus 로고
    • Intestinal anastomosis healing in rat: Collagen concentration and histochemical characterization by Picrosirius red staining and polarizing microscopy
    • Rabau MY, Hirshberg A, Hiss Y, Dayan D: Intestinal anastomosis healing in rat: collagen concentration and histochemical characterization by Picrosirius red staining and polarizing microscopy. Exp Mol Pathol 1995, 62:160-165
    • (1995) Exp Mol Pathol , vol.62 , pp. 160-165
    • Rabau, M.Y.1    Hirshberg, A.2    Hiss, Y.3    Dayan, D.4
  • 32
    • 0032798297 scopus 로고    scopus 로고
    • Use of the Picrosinus-polarization method to age fibrotic lesions in the hepatic granulomas produced in experimental murine schistosomiasis
    • Andrade GB, Montes GS, Conceicao GM, Sardiva PH: Use of the Picrosinus-polarization method to age fibrotic lesions in the hepatic granulomas produced in experimental murine schistosomiasis. Ann Trod Med Parasitol 1999, 93:265-272
    • (1999) Ann Trod Med Parasitol , vol.93 , pp. 265-272
    • Andrade, G.B.1    Montes, G.S.2    Conceicao, G.M.3    Sardiva, P.H.4
  • 33
    • 0034023371 scopus 로고    scopus 로고
    • Functions of mammalian Smad genes as revealed by targeted gene disruption in mice
    • Weinstein M, Yang X, Deng C: Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. Cytokine Growth Factor Rev 2000, 11:49-58
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 49-58
    • Weinstein, M.1    Yang, X.2    Deng, C.3
  • 34
    • 0035907240 scopus 로고    scopus 로고
    • Identification of novel TGF-beta/Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach
    • Verrecchia F, Chu ML, Mauviel A: Identification of novel TGF-beta/Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach. J Biol Chem 2001, 276:17058-17062
    • (2001) J Biol Chem , vol.276 , pp. 17058-17062
    • Verrecchia, F.1    Chu, M.L.2    Mauviel, A.3
  • 36
    • 0033214191 scopus 로고    scopus 로고
    • Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair
    • Munz B, Smola H, Engelhardt F, Bleuel K, Brauchle M, Lein I, Evans LW, Huylebroeck D, Balling R, Werner S: Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair. EMBO J 1999, 18:5205-5215
    • (1999) EMBO J , vol.18 , pp. 5205-5215
    • Munz, B.1    Smola, H.2    Engelhardt, F.3    Bleuel, K.4    Brauchle, M.5    Lein, I.6    Evans, L.W.7    Huylebroeck, D.8    Balling, R.9    Werner, S.10
  • 37
    • 0035477312 scopus 로고    scopus 로고
    • Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis
    • Wankell M, Munz B, Hubner G, Hans W, Wolf E, Goppelt A, Werner S: Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis. EMBO J 2001, 20:5361-5372
    • (2001) EMBO J , vol.20 , pp. 5361-5372
    • Wankell, M.1    Munz, B.2    Hubner, G.3    Hans, W.4    Wolf, E.5    Goppelt, A.6    Werner, S.7
  • 39
    • 0033813903 scopus 로고    scopus 로고
    • Connective tissue growth factor: What's in a name?
    • Moussad EE, Brigstock DR: Connective tissue growth factor: what's in a name? Mol Genet Metab 2000, 71:276-292
    • (2000) Mol Genet Metab , vol.71 , pp. 276-292
    • Moussad, E.E.1    Brigstock, D.R.2
  • 40
    • 0035498841 scopus 로고    scopus 로고
    • Signaling events required for transforming growth factor-beta stimulation of connective tissue growth factor expression by cultured human lung fibroblasts
    • Kucich U, Rosenbloom JC, Herrick DJ, Abrams WR, Hamilton AD, Sebti SM, Rosenbloom J: Signaling events required for transforming growth factor-beta stimulation of connective tissue growth factor expression by cultured human lung fibroblasts. Arch Biochem Biophys 2001, 395:103-112
    • (2001) Arch Biochem Biophys , vol.395 , pp. 103-112
    • Kucich, U.1    Rosenbloom, J.C.2    Herrick, D.J.3    Abrams, W.R.4    Hamilton, A.D.5    Sebti, S.M.6    Rosenbloom, J.7
  • 41
    • 0035815683 scopus 로고    scopus 로고
    • Ctgf and smads, maintenance of scleroderma phenotype is independent of smad signaling
    • Holmes A, Abraham DJ, Sa S, Shiwen X, Black CM, Leask A: Ctgf and smads, maintenance of scleroderma phenotype is independent of smad signaling. J Biol Chem 2001, 276:10594-10601
    • (2001) J Biol Chem , vol.276 , pp. 10594-10601
    • Holmes, A.1    Abraham, D.J.2    Sa, S.3    Shiwen, X.4    Black, C.M.5    Leask, A.6
  • 42
    • 0033613944 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase kinase 2 activation is essential for progression through the G2/M checkpoint arrest in cells exposed to ionizing radiation
    • Abbott DW, Holt JT: Mitogen-activated protein kinase kinase 2 activation is essential for progression through the G2/M checkpoint arrest in cells exposed to ionizing radiation. J Biol Chem 1999, 274:2732-2742
    • (1999) J Biol Chem , vol.274 , pp. 2732-2742
    • Abbott, D.W.1    Holt, J.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.