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Volumn 172, Issue 4, 2004, Pages 2155-2162

Reduced Ig Class Switch in Aged Mice Correlates with Decreased E47 and Activation-Induced Cytidine Deaminase

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; CYTIDINE DEAMINASE; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN HEAVY CHAIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2A; TRANSCRIPTION FACTOR E47; UNCLASSIFIED DRUG;

EID: 0842321787     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.4.2155     Document Type: Article
Times cited : (119)

References (47)
  • 1
    • 0017506483 scopus 로고
    • Immune function in aged mice. I. T-cell responsiveness using phytohaemagglutinin as a functional probe
    • Callard, R. E., and A. Basten. 1977. Immune function in aged mice. I. T-cell responsiveness using phytohaemagglutinin as a functional probe. Cell. Immunol. 31:13.
    • (1977) Cell. Immunol. , vol.31 , pp. 13
    • Callard, R.E.1    Basten, A.2
  • 2
    • 0018967672 scopus 로고
    • Age-related decline in the in vitro and in vivo syntheses of anti-tetanus toxoid antibody in humans
    • Kishimoto, S., S. Tomino, H. Mitsuya, H. Fujiwara, and H. Tsuda. 1980. Age-related decline in the in vitro and in vivo syntheses of anti-tetanus toxoid antibody in humans. J. Immunol. 125:2347.
    • (1980) J. Immunol. , vol.125 , pp. 2347
    • Kishimoto, S.1    Tomino, S.2    Mitsuya, H.3    Fujiwara, H.4    Tsuda, H.5
  • 3
    • 0031448877 scopus 로고    scopus 로고
    • The B-cell biology of aging
    • Klinman, N. R., and G. H. Kline. 1997. The B-cell biology of aging. Immunol. Rev. 160:103.
    • (1997) Immunol. Rev. , vol.160 , pp. 103
    • Klinman, N.R.1    Kline, G.H.2
  • 4
    • 0027252520 scopus 로고
    • Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae
    • Nicoletti, C., X. Yang, and J. Cerny. 1993. Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae. J. Immunol. 150:543.
    • (1993) J. Immunol. , vol.150 , pp. 543
    • Nicoletti, C.1    Yang, X.2    Cerny, J.3
  • 8
    • 0028355045 scopus 로고
    • L gene utilization in splenic antibody foci by in situ hybridization
    • L gene utilization in splenic antibody foci by in situ hybridization. J. Immunol. 152:2214.
    • (1994) J. Immunol. , vol.152 , pp. 2214
    • Yang, X.1    Stedra, J.2    Cerny, J.3
  • 9
    • 0036670717 scopus 로고    scopus 로고
    • Hyper-IgM syndromes: A model for studying the regulation of class switch recombination and somatic hypermutation generation
    • Durandy, A. 2002. Hyper-IgM syndromes: a model for studying the regulation of class switch recombination and somatic hypermutation generation. Biochem. Soc. Trans. 30:815.
    • (2002) Biochem. Soc. Trans. , vol.30 , pp. 815
    • Durandy, A.1
  • 11
    • 0035898937 scopus 로고    scopus 로고
    • Immune responses and protection in different strains of aged mice immunized intranasally with an adjuvant-combined influenza vaccine
    • Asanuma, H., K. Hirokawa, M. Uchiyama, Y. Suzuki, C. Aizawa, T. Kurata, T. Sata, and S. Tamura. 2001. Immune responses and protection in different strains of aged mice immunized intranasally with an adjuvant-combined influenza vaccine. Vaccine 19:3981.
    • (2001) Vaccine , vol.19 , pp. 3981
    • Asanuma, H.1    Hirokawa, K.2    Uchiyama, M.3    Suzuki, Y.4    Aizawa, C.5    Kurata, T.6    Sata, T.7    Tamura, S.8
  • 12
    • 0037012001 scopus 로고    scopus 로고
    • Role of humoral and cell-mediated immunity in protection from influenza disease after immunization of healthy elderly
    • Murasko, D. M., E. D. Bernstein, E. M. Gardner, P. Gross, G. Munk, S. Dran, and E. Abrutyn. 2002. Role of humoral and cell-mediated immunity in protection from influenza disease after immunization of healthy elderly. Exp. Gerontol. 37:427.
    • (2002) Exp. Gerontol. , vol.37 , pp. 427
    • Murasko, D.M.1    Bernstein, E.D.2    Gardner, E.M.3    Gross, P.4    Munk, G.5    Dran, S.6    Abrutyn, E.7
  • 13
    • 0037310619 scopus 로고    scopus 로고
    • Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice
    • Han, S., K. Yang, Z. Ozen, W. Peng, E. Marinova, G. Kelsoe, and B. Zheng. 2003. Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice. J. Immunol. 170:1267.
    • (2003) J. Immunol. , vol.170 , pp. 1267
    • Han, S.1    Yang, K.2    Ozen, Z.3    Peng, W.4    Marinova, E.5    Kelsoe, G.6    Zheng, B.7
  • 14
    • 0017167094 scopus 로고
    • Immunological studies of aging. II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice
    • Goidl, E. A., J. B. Innes, and M. E. Weksler. 1976. Immunological studies of aging. II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice. J. Exp. Med. 144:1037.
    • (1976) J. Exp. Med. , vol.144 , pp. 1037
    • Goidl, E.A.1    Innes, J.B.2    Weksler, M.E.3
  • 15
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu, M., K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102:553.
    • (2000) Cell , vol.102 , pp. 553
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 16
    • 0036212917 scopus 로고    scopus 로고
    • Molecular mechanism of class switch recombination: Linkage with somatic hypermutation
    • Honjo, T., K. Kinoshita, and M. Muramatsu. 2002. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu. Rev. Immunol. 20:165.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 165
    • Honjo, T.1    Kinoshita, K.2    Muramatsu, M.3
  • 17
    • 0038515309 scopus 로고    scopus 로고
    • E-proteins directly regulate expression of activation-induced deaminase in mature B cells
    • Sayegh, C. E., M. W. Quong, Y. Agata, and C. Murre. 2003. E-proteins directly regulate expression of activation-induced deaminase in mature B cells. Nat. Immun. 4:586.
    • (2003) Nat. Immun. , vol.4 , pp. 586
    • Sayegh, C.E.1    Quong, M.W.2    Agata, Y.3    Murre, C.4
  • 19
    • 0026045243 scopus 로고
    • Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line
    • Schlissel, M., A. Voronova, and D. Baltimore. 1991. Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line. Genes Dev. 5:1367.
    • (1991) Genes Dev. , vol.5 , pp. 1367
    • Schlissel, M.1    Voronova, A.2    Baltimore, D.3
  • 20
    • 0030790713 scopus 로고    scopus 로고
    • EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes
    • Sigvardsson, M., M. O'Riordan, and R. Grosschedl. 1997. EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes. Immunity 7:25.
    • (1997) Immunity , vol.7 , pp. 25
    • Sigvardsson, M.1    O'Riordan, M.2    Grosschedl, R.3
  • 21
    • 0033980393 scopus 로고    scopus 로고
    • Helix-loop-helix proteins: Regulators of transcription in eucaryotic organisms
    • Massari, M. E., and C. Murre. 2000. Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Mol. Cell. Biol. 20:429.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 429
    • Massari, M.E.1    Murre, C.2
  • 22
    • 0037080629 scopus 로고    scopus 로고
    • IL-7Rα and E47: Independent pathways required for development of multipotent lymphoid progenitors
    • Kee, B. L., G. Bain, and C. Murre. 2002. IL-7Rα and E47: independent pathways required for development of multipotent lymphoid progenitors. EMBO J. 21:103.
    • (2002) EMBO J. , vol.21 , pp. 103
    • Kee, B.L.1    Bain, G.2    Murre, C.3
  • 23
    • 0037438596 scopus 로고    scopus 로고
    • Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice
    • Frasca, D., D. Nguyen, R. L. Riley, and B. B. Blomberg. 2003. Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice. J. Immunol. 170:719.
    • (2003) J. Immunol. , vol.170 , pp. 719
    • Frasca, D.1    Nguyen, D.2    Riley, R.L.3    Blomberg, B.B.4
  • 24
    • 0035924703 scopus 로고    scopus 로고
    • The regulation and function of the Id proteins in lymphocyte development
    • Rivera, R., and C. Murre. 2001. The regulation and function of the Id proteins in lymphocyte development. Oncogene 20:8308.
    • (2001) Oncogene , vol.20 , pp. 8308
    • Rivera, R.1    Murre, C.2
  • 25
    • 0027081048 scopus 로고
    • Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis
    • Zhuang, Y., C. G. Kim, S. Bartelmez, P. Cheng, M. Groudine, and H. Weintraub. 1992. Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis. Proc. Natl. Acad. Sci. USA 89:12132.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 12132
    • Zhuang, Y.1    Kim, C.G.2    Bartelmez, S.3    Cheng, P.4    Groudine, M.5    Weintraub, H.6
  • 26
    • 0033166301 scopus 로고    scopus 로고
    • Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A
    • O'Riordan, M., and R. Grosschedl. 1999. Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. Immunity 11:21.
    • (1999) Immunity , vol.11 , pp. 21
    • O'Riordan, M.1    Grosschedl, R.2
  • 27
    • 0023814675 scopus 로고
    • IL-4 induces co-expression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipopolysaccharide
    • Snapper, C. M., F. D. Finkelman, D. Stefany, D. H. Conrad, and W. E. Paul. 1988. IL-4 induces co-expression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipopolysaccharide. J. Immunol. 141:489.
    • (1988) J. Immunol. , vol.141 , pp. 489
    • Snapper, C.M.1    Finkelman, F.D.2    Stefany, D.3    Conrad, D.H.4    Paul, W.E.5
  • 28
    • 0027422972 scopus 로고
    • E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development
    • Jacobs, Y., C. Vierra, and C. Nelson. 1993. E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development. Mol. Cell. Biol. 13:7321.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7321
    • Jacobs, Y.1    Vierra, C.2    Nelson, C.3
  • 29
  • 30
    • 0030746109 scopus 로고    scopus 로고
    • Interaction of DNA-dependent protein kinase with DNA and with Ku: Biochemical and atomic-force microscopy studies
    • Yaneva, M., T. Kowalewski, and M. R. Lieber. 1997. Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J. 16:5098.
    • (1997) EMBO J. , vol.16 , pp. 5098
    • Yaneva, M.1    Kowalewski, T.2    Lieber, M.R.3
  • 31
    • 0034990322 scopus 로고    scopus 로고
    • Role of DNA-dependent protein kinase in recognition of radiation-induced DNA damage in human peripheral blood mononuclear cells
    • Frasca, D., P. Barattini, G. Tocchi, L. Guidi, L. Pierelli, and G. Doria. 2001. Role of DNA-dependent protein kinase in recognition of radiation-induced DNA damage in human peripheral blood mononuclear cells. Int. Immunol. 13:791.
    • (2001) Int. Immunol. , vol.13 , pp. 791
    • Frasca, D.1    Barattini, P.2    Tocchi, G.3    Guidi, L.4    Pierelli, L.5    Doria, G.6
  • 33
    • 0025114448 scopus 로고
    • Immunoglobulin switch circular DNA in the mouse infected with Nippostrongylus brasiliensis: Evidence for successive class switching from μ to ε via γ1
    • Yoshida, K., M. Matsuoka, S. Usuda, A. Mori, K. Ishizaka, and H. Sakano. 1990. Immunoglobulin switch circular DNA in the mouse infected with Nippostrongylus brasiliensis: evidence for successive class switching from μ to ε via γ1. Proc. Natl. Acad. Sci. USA 87:7829.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7829
    • Yoshida, K.1    Matsuoka, M.2    Usuda, S.3    Mori, A.4    Ishizaka, K.5    Sakano, H.6
  • 34
    • 0033571526 scopus 로고    scopus 로고
    • E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination
    • Quong, M. W., D. P. Harris, S. L. Swain, and C. Murre. 1999. E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination. EMBO J. 18:6307.
    • (1999) EMBO J. , vol.18 , pp. 6307
    • Quong, M.W.1    Harris, D.P.2    Swain, S.L.3    Murre, C.4
  • 35
    • 0037396302 scopus 로고    scopus 로고
    • Effects of aging on proliferation and E47 transcription factor activity induced by different stimuli in murine splenic B cells
    • Frasca, D., D. Nguyen, R. L. Riley, and B. B. Blomberg. 2003. Effects of aging on proliferation and E47 transcription factor activity induced by different stimuli in murine splenic B cells. Mech. Ageing Dev. 124:361.
    • (2003) Mech. Ageing Dev. , vol.124 , pp. 361
    • Frasca, D.1    Nguyen, D.2    Riley, R.L.3    Blomberg, B.B.4
  • 36
    • 0037108509 scopus 로고    scopus 로고
    • Isotype switching by human B cells is division-associated and regulated by cytokines
    • Tangye, S. G., A. Ferguson. D. T. Avery, C. S. Ma, and P. D. Hodgkin. 2002. Isotype switching by human B cells is division-associated and regulated by cytokines. J. Immunol. 169:4298.
    • (2002) J. Immunol. , vol.169 , pp. 4298
    • Tangye, S.G.1    Ferguson, A.2    Avery, D.T.3    Ma, C.S.4    Hodgkin, P.D.5
  • 38
    • 0031435618 scopus 로고    scopus 로고
    • Age-related changes in antibody repertoire: Contribution from T cells
    • Song, H., P. D. Price, and J. Cerny. 1997. Age-related changes in antibody repertoire: contribution from T cells. Immunol. Rev. 160:55.
    • (1997) Immunol. Rev. , vol.160 , pp. 55
    • Song, H.1    Price, P.D.2    Cerny, J.3
  • 40
    • 0026045153 scopus 로고
    • Human B cell proliferative responses during aging: Reduced RNA synthesis and DNA replication after signal transduction by surface immunoglobulins compared to B cell antigenic determinants CD20 and CD40
    • Whisler, R. L., J. W. Williams, Jr., and Y. G. Newhouse. 1991. Human B cell proliferative responses during aging: reduced RNA synthesis and DNA replication after signal transduction by surface immunoglobulins compared to B cell antigenic determinants CD20 and CD40. Mech. Ageing Dev. 61:209.
    • (1991) Mech. Ageing Dev. , vol.61 , pp. 209
    • Whisler, R.L.1    Williams Jr., J.W.2    Newhouse, Y.G.3
  • 41
  • 45
    • 0041931059 scopus 로고    scopus 로고
    • The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription
    • Michael, N., H. M. Shen, S. Longerich, N. Kim, A. Longacre, and U. Storb. 2003. The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription. Immunity 19:235.
    • (2003) Immunity , vol.19 , pp. 235
    • Michael, N.1    Shen, H.M.2    Longerich, S.3    Kim, N.4    Longacre, A.5    Storb, U.6
  • 46
    • 0141798672 scopus 로고    scopus 로고
    • Expression of activation-induced cytidine deaminase decreases throughout the life
    • Radu, D. L., T. Kodera, and C. Bona. 2003. Expression of activation-induced cytidine deaminase decreases throughout the life. J. Cell Mol. Med. 7:141.
    • (2003) J. Cell Mol. Med. , vol.7 , pp. 141
    • Radu, D.L.1    Kodera, T.2    Bona, C.3
  • 47
    • 85039568728 scopus 로고    scopus 로고
    • Age-related differences in the E2A-encoded transcription factor E47 in bone marrow-derived B cell precursors and in splenic B cells
    • In press
    • Frasca, D., E. Van der Put, R. L. Riley, and B. B. Blomberg. Age-related differences in the E2A-encoded transcription factor E47 in bone marrow-derived B cell precursors and in splenic B cells. Exp. Gerontol. In press.
    • Exp. Gerontol.
    • Frasca, D.1    Van Der Put, E.2    Riley, R.L.3    Blomberg, B.B.4


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