메뉴 건너뛰기




Volumn 62, Issue 12, 2005, Pages 1322-1332

Oral tolerance and regulation of mucosal immunity

Author keywords

Commensal flora; Dendritic cells; Intestine; Regulatory CD4+ T cells; Tolerance

Indexed keywords

ANTIGEN; CD11 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE; CHEMOKINE CCL20; CYTOKINE; HYBRID PROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 4; LYMPHOTOXIN BETA RECEPTOR IMMUNOGLOBULIN; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RECEPTOR 1 IMMUNOGLOBULIN; UNCLASSIFIED DRUG;

EID: 20744459116     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-005-5036-0     Document Type: Review
Times cited : (67)

References (144)
  • 1
    • 0038316325 scopus 로고    scopus 로고
    • Anatomical basis of tolerance and immunity to intestinal antigens
    • Mowat A. M. (2003) Anatomical basis of tolerance and immunity to intestinal antigens. Nat. Rev. Immunol. 3: 331-341
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 331-341
    • Mowat, A.M.1
  • 2
    • 0033003599 scopus 로고    scopus 로고
    • Oral tolerance in disease
    • Garside P., Mowat A. M. and Khoruts A. (1999) Oral tolerance in disease. Gut 44: 137-142
    • (1999) Gut , vol.44 , pp. 137-142
    • Garside, P.1    Mowat, A.M.2    Khoruts, A.3
  • 3
    • 0019488912 scopus 로고
    • Simultaneous induction of antigen-specific IgA helper T cells and IgG suppressor T cells in the murine Peyer's patch after protein feeding
    • Richman L. K., Graeff A. S., Yarchoan R. and Strober W. (1981) Simultaneous induction of antigen-specific IgA helper T cells and IgG suppressor T cells in the murine Peyer's patch after protein feeding. J. Immunol. 126: 2079-2083
    • (1981) J. Immunol. , vol.126 , pp. 2079-2083
    • Richman, L.K.1    Graeff, A.S.2    Yarchoan, R.3    Strober, W.4
  • 4
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y., Kuchroo V. K., Inobe J., Hafler D. A. and Weiner H. L. (1994) Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265: 1237-1240
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 6
    • 0035063241 scopus 로고    scopus 로고
    • Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches
    • Spahn T. W., Fontana A., Faria A. M., Slavin A. J., Engster H. P., Zhang X. et al. (2001) Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches. Eur. J. Immunol. 31: 1278-1287
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1278-1287
    • Spahn, T.W.1    Fontana, A.2    Faria, A.M.3    Slavin, A.J.4    Engster, H.P.5    Zhang, X.6
  • 7
    • 0035871627 scopus 로고    scopus 로고
    • The role of dendritic cells, B cells, and M cells in gut-oriented immune responses
    • Alpan O., Rudomen G. and Matzinger P. (2001) The role of dendritic cells, B cells, and M cells in gut-oriented immune responses. J. Immunol. 166: 4843-4852
    • (2001) J. Immunol. , vol.166 , pp. 4843-4852
    • Alpan, O.1    Rudomen, G.2    Matzinger, P.3
  • 8
    • 0022600983 scopus 로고
    • Induction of oral tolerance in rats without Peyer's patches
    • Enders G., Gottwald T. and Brendel W. (1986) Induction of oral tolerance in rats without Peyer's patches. Immunology 58: 311-314
    • (1986) Immunology , vol.58 , pp. 311-314
    • Enders, G.1    Gottwald, T.2    Brendel, W.3
  • 9
    • 0036237353 scopus 로고    scopus 로고
    • Mesenteric lymph nodes are critical for the induction of high-dose oral tolerance in the absence of Peyer's patches
    • Spahn T. W., Weiner H. L., Rennert P. D., Lugering N., Fontana A., Domschke W et al. (2002) Mesenteric lymph nodes are critical for the induction of high-dose oral tolerance in the absence of Peyer's patches. Eur. J. Immunol. 32: 1109-1113
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1109-1113
    • Spahn, T.W.1    Weiner, H.L.2    Rennert, P.D.3    Lugering, N.4    Fontana, A.5    Domschke, W.6
  • 10
    • 0037959915 scopus 로고    scopus 로고
    • Visualization of peptide presentation following oral application of antigen in normal and Peyer's patches-deficient mice
    • Kunkel D., Kirchhoff D., Nishikawa S., Radbruch A. and Scheffold A. (2003) Visualization of peptide presentation following oral application of antigen in normal and Peyer's patches-deficient mice. Eur. J. Immunol. 33: 1292-1301
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1292-1301
    • Kunkel, D.1    Kirchhoff, D.2    Nishikawa, S.3    Radbruch, A.4    Scheffold, A.5
  • 11
    • 0032890142 scopus 로고    scopus 로고
    • Epithelial cells in antigen. Sampling and presentation in mucosal tissues
    • Kaiserlian D. (1999) Epithelial cells in antigen. Sampling and presentation in mucosal tissues. Curr. Top. Microbiol. Immunol. 236: 55-78
    • (1999) Curr. Top. Microbiol. Immunol. , vol.236 , pp. 55-78
    • Kaiserlian, D.1
  • 12
    • 0032528838 scopus 로고    scopus 로고
    • Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells
    • Hershberg R. M., Cho D. H., Youakim A., Bradley M. B., Lee J. S., Framson P. E. et al. (1998) Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells. J. Clin. Invest. 102: 792-803
    • (1998) J. Clin. Invest. , vol.102 , pp. 792-803
    • Hershberg, R.M.1    Cho, D.H.2    Youakim, A.3    Bradley, M.B.4    Lee, J.S.5    Framson, P.E.6
  • 13
    • 0033982498 scopus 로고    scopus 로고
    • Modulation of antigen trafficking to MHC class II-positive late endosomes of enterocytes
    • Zimmer K. P., Buning J., Weber P., Kaiserlian D. and Strobel S. (2000) Modulation of antigen trafficking to MHC class II-positive late endosomes of enterocytes. Gastroenterology 118: 128-137
    • (2000) Gastroenterology , vol.118 , pp. 128-137
    • Zimmer, K.P.1    Buning, J.2    Weber, P.3    Kaiserlian, D.4    Strobel, S.5
  • 14
    • 0033996191 scopus 로고    scopus 로고
    • Antigen processing and presentation by intestinal epithelial cells polarity and complexity
    • Hershberg R. M. and Mayer L. F. (2000) Antigen processing and presentation by intestinal epithelial cells polarity and complexity. Immunol. Today 21: 123-128
    • (2000) Immunol. Today , vol.21 , pp. 123-128
    • Hershberg, R.M.1    Mayer, L.F.2
  • 15
    • 0027451461 scopus 로고
    • Unexpected lack of reactivity of allogeneic anti-Ia monoclonal antibodies with MHC class II molecules expressed by mouse intestinal epithelial cells
    • Vidai K., Samarut C., Magaud J. P., Revillard J. P. and Kaiserlian D. (1993) Unexpected lack of reactivity of allogeneic anti-Ia monoclonal antibodies with MHC class II molecules expressed by mouse intestinal epithelial cells. J. Immunol. 151: 4642-4650
    • (1993) J. Immunol. , vol.151 , pp. 4642-4650
    • Vidai, K.1    Samarut, C.2    Magaud, J.P.3    Revillard, J.P.4    Kaiserlian, D.5
  • 16
    • 0036828289 scopus 로고    scopus 로고
    • Expansion of CD8+ T cells with regulatory function after interaction with intestinal epithelial cells
    • Allez M., Brimnes J., Dotan I. and Mayer L. (2002) Expansion of CD8+ T cells with regulatory function after interaction with intestinal epithelial cells. Gastroenterology 123: 1516-1526
    • (2002) Gastroenterology , vol.123 , pp. 1516-1526
    • Allez, M.1    Brimnes, J.2    Dotan, I.3    Mayer, L.4
  • 17
    • 2342428651 scopus 로고    scopus 로고
    • Colonic epithelial cell-mediated suppression of CD4 T cell activation
    • Cruickshank S. M., McVay L. D., Baumgart D. C., Felsburg P. J. and Carding S. R. (2004) Colonic epithelial cell-mediated suppression of CD4 T cell activation. Gut 53: 678-684
    • (2004) Gut , vol.53 , pp. 678-684
    • Cruickshank, S.M.1    McVay, L.D.2    Baumgart, D.C.3    Felsburg, P.J.4    Carding, S.R.5
  • 18
    • 0029065553 scopus 로고
    • Oral tolerance to haptens: Intestinal epithelial cells from 2.4-dinitrochlorobenzene-fed mice inhibit hapten-specific T cell activation in vitro
    • Galliaerde V., Desvignes C., Peyron E. and Kaiserlian D. (1995) Oral tolerance to haptens: intestinal epithelial cells from 2.4-dinitrochlorobenzene- fed mice inhibit hapten-specific T cell activation in vitro. Eur. J. Immunol. 25: 1385-1390
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1385-1390
    • Galliaerde, V.1    Desvignes, C.2    Peyron, E.3    Kaiserlian, D.4
  • 19
    • 0034614894 scopus 로고    scopus 로고
    • A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes
    • Huang F. P,. Platt N., Wykes M., Major J. R., Powell T. J., Jenkins C. D. et al. (2000) A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J. Exp. Med. 191: 435-443
    • (2000) J. Exp. Med. , vol.191 , pp. 435-443
    • Huang, F.P.1    Platt, N.2    Wykes, M.3    Major, J.R.4    Powell, T.J.5    Jenkins, C.D.6
  • 21
    • 0035923513 scopus 로고    scopus 로고
    • Flagellin stimulation of intestinal epithelial cells triggers CCE20- mediated migration of dendritic cells
    • Sierro F., Dubois B., Coste A., Kaiserlian D., Kraehenbuhl J. P. and Sirard J. C. (2001) Flagellin stimulation of intestinal epithelial cells triggers CCE20- mediated migration of dendritic cells. Proc. Natl. Acad. Sci. USA 98: 13722-13727
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 13722-13727
    • Sierro, F.1    Dubois, B.2    Coste, A.3    Kaiserlian, D.4    Kraehenbuhl, J.P.5    Sirard, J.C.6
  • 22
    • 0034284803 scopus 로고    scopus 로고
    • Prokaryotic regulation of epithelial responses by inhibition of IκB-α ubiquitination
    • Neish A. S., Gewirtz A. T., Zeng H., Young A. N., Hobert M. E., Karmali V. et al. (2000) Prokaryotic regulation of epithelial responses by inhibition of IκB-α ubiquitination. Science 289: 1560-1563
    • (2000) Science , vol.289 , pp. 1560-1563
    • Neish, A.S.1    Gewirtz, A.T.2    Zeng, H.3    Young, A.N.4    Hobert, M.E.5    Karmali, V.6
  • 23
    • 0347756655 scopus 로고    scopus 로고
    • Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and Re1A
    • Kelly D., Campbell J. I., King T. P., Grant G., Jansson E. A., Courts A. G. et al. (2004) Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and Re1A. Nat. Immunol. 5: 104-112
    • (2004) Nat. Immunol. , vol.5 , pp. 104-112
    • Kelly, D.1    Campbell, J.I.2    King, T.P.3    Grant, G.4    Jansson, E.A.5    Courts, A.G.6
  • 24
    • 0032525034 scopus 로고    scopus 로고
    • In situ immune response in gut-associated lymphoid tissue (GAET) following oral antigen in TCR-transgenic mice
    • Gonnella P. A., Chen Y., Inobe J., Komagata Y., Quartulli M. and Weiner H. L. (1998) In situ immune response in gut-associated lymphoid tissue (GAET) following oral antigen in TCR-transgenic mice. J. Immunol. 160: 4708-4718
    • (1998) J. Immunol. , vol.160 , pp. 4708-4718
    • Gonnella, P.A.1    Chen, Y.2    Inobe, J.3    Komagata, Y.4    Quartulli, M.5    Weiner, H.L.6
  • 25
    • 0031179646 scopus 로고    scopus 로고
    • IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells
    • Kalinski P., Hilkens C. M., Snijders A., Snijdewint F. G. and Kapsenberg M. L. (1997) IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. J Immunol 159: 28-35
    • (1997) J. Immunol. , vol.159 , pp. 28-35
    • Kalinski, P.1    Hilkens, C.M.2    Snijders, A.3    Snijdewint, F.G.4    Kapsenberg, M.L.5
  • 26
    • 0030022290 scopus 로고    scopus 로고
    • Class II MHC antigen (Ia)-bearing dendritic cells in the epithelium of the rat intestine
    • Maric I., Holt P. G., Perdue M. H. and Bienenstock J. (1996) Class II MHC antigen (Ia)-bearing dendritic cells in the epithelium of the rat intestine. J. Immunol. 156: 1408-1414
    • (1996) J. Immunol. , vol.156 , pp. 1408-1414
    • Maric, I.1    Holt, P.G.2    Perdue, M.H.3    Bienenstock, J.4
  • 27
    • 0035321325 scopus 로고    scopus 로고
    • Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
    • Rescigno M., Urbano M., Valzasina B., Francolini M., Rotta G., Bonasio R. et al. (2001) Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat. Immunol. 2: 361-367
    • (2001) Nat. Immunol. , vol.2 , pp. 361-367
    • Rescigno, M.1    Urbano, M.2    Valzasina, B.3    Francolini, M.4    Rotta, G.5    Bonasio, R.6
  • 28
    • 0027410872 scopus 로고
    • Antigen acquisition by dendritic cells: Intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo
    • Liu L. M. and MacPherson G. G. (1993) Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo. J. Exp. Med. 177: 1299-1307
    • (1993) J. Exp. Med. , vol.177 , pp. 1299-1307
    • Liu, L.M.1    MacPherson, G.G.2
  • 29
    • 0025051094 scopus 로고
    • The generation of a 'tolerogen' after the ingestion of ovalbumin is time-dependent and unrelated to serum levels of immunoreactive antigen
    • Peng H. J., Turner M. W. and Strobel S. (1990) The generation of a 'tolerogen' after the ingestion of ovalbumin is time-dependent and unrelated to serum levels of immunoreactive antigen. Clin. Exp. Immunol. 81: 510-515
    • (1990) Clin. Exp. Immunol. , vol.81 , pp. 510-515
    • Peng, H.J.1    Turner, M.W.2    Strobel, S.3
  • 30
    • 0032789856 scopus 로고    scopus 로고
    • Visualizing the T-cell response elicited by oral administration of soluble protein antigen
    • Williamson E., O'Malley J. M. and Viney J. L. ( 1999) Visualizing the T-cell response elicited by oral administration of soluble protein antigen. Immunology 97: 565-572
    • (1999) Immunology , vol.97 , pp. 565-572
    • Williamson, E.1    O'Malley, J.M.2    Viney, J.L.3
  • 31
    • 0033563273 scopus 로고    scopus 로고
    • Antigen-specific T cell activation and proliferation during oral tolerance induction
    • Sun J. Dirden-Kramer B., Ito K., Ernst P. B. and Van Houten N. (1999) Antigen-specific T cell activation and proliferation during oral tolerance induction. J. Immunol. 162: 5868-5875
    • (1999) J. Immunol. , vol.162 , pp. 5868-5875
    • Sun, J.1    Dirden-Kramer, B.2    Ito, K.3    Ernst, P.B.4    Van Houten, N.5
  • 33
    • 0033783588 scopus 로고    scopus 로고
    • T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen
    • Benson J. M., Campbell K. A., Guan Z., Gienapp I. E., Stuckman S. S., Forsthuber T. et al. (2000) T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen. J. Clin. Invest. 106: 1031-1038.
    • (2000) J. Clin. Invest. , vol.106 , pp. 1031-1038
    • Benson, J.M.1    Campbell, K.A.2    Guan, Z.3    Gienapp, I.E.4    Stuckman, S.S.5    Forsthuber, T.6
  • 34
    • 0032100767 scopus 로고    scopus 로고
    • Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen
    • Gutgemann I., Fahrer A. M., Altman J. D., Davis M. M. and Chien Y. H. (1998) Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen. Immunity 8: 667-673
    • (1998) Immunity , vol.8 , pp. 667-673
    • Gutgemann, I.1    Fahrer, A.M.2    Altman, J.D.3    Davis, M.M.4    Chien, Y.H.5
  • 35
    • 0037767957 scopus 로고    scopus 로고
    • An investigation of the distribution of antigen fed in tolerogenic or immunogenic forms
    • Kobets N., Kennedy K. and Garside P. (2003) An investigation of the distribution of antigen fed in tolerogenic or immunogenic forms. Immunol. Lett. 88: 147-155
    • (2003) Immunol. Lett. , vol.88 , pp. 147-155
    • Kobets, N.1    Kennedy, K.2    Garside, P.3
  • 36
    • 0036278333 scopus 로고    scopus 로고
    • T-cell activation occurs simultaneously in local and peripheral lymphoid tissue following oral administration of a range of doses of immunogenic or tolerogenic antigen, although tolerized T cells display a defect in cell division
    • Smith K. M., Davidson J. M. and P. Garside (2002) T-cell activation occurs simultaneously in local and peripheral lymphoid tissue following oral administration of a range of doses of immunogenic or tolerogenic antigen, although tolerized T cells display a defect in cell division. Immunology 106: 144-158
    • (2002) Immunology , vol.106 , pp. 144-158
    • Smith, K.M.1    Davidson, J.M.2    Garside, P.3
  • 37
    • 0034808696 scopus 로고    scopus 로고
    • Immunohistochemical detection of protein adducts of 2,4- dinitrochlorobenzene in antigen-presenting cells and lymphocytes after oral administration to mice: Lack of a role of Kupffer cells in oral tolerance
    • Ju C. and Pohl L. R. (2001) Immunohistochemical detection of protein adducts of 2,4-dinitrochlorobenzene in antigen-presenting cells and lymphocytes after oral administration to mice: lack of a role of Kupffer cells in oral tolerance. Chem. Res. Toxicol. 14: 1209-1217
    • (2001) Chem. Res. Toxicol. , vol.14 , pp. 1209-1217
    • Ju, C.1    Pohl, L.R.2
  • 38
    • 0019990532 scopus 로고
    • Inhibition of specific immune responses by feeding protein antigens. V. Induction of the tolerant state in the absence of specific suppressor T cells
    • Hanson D. G. and Miller S. D. (1982) Inhibition of specific immune responses by feeding protein antigens. V. Induction of the tolerant state in the absence of specific suppressor T cells. J. Immunol. 128: 2378-2381
    • (1982) J. Immunol. , vol.128 , pp. 2378-2381
    • Hanson, D.G.1    Miller, S.D.2
  • 39
    • 0028358048 scopus 로고
    • Induction of anergy or active suppression following oral tolerance is determined by antigen dosage
    • Friedman A. and Weiner H. L. (1994) Induction of anergy or active suppression following oral tolerance is determined by antigen dosage. Proc. Natl. Acad. Sci. 91: 6688-6692
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 6688-6692
    • Friedman, A.1    Weiner, H.L.2
  • 40
    • 0029031681 scopus 로고
    • Peripheral deletion of antigen-reactive T cells in oral tolerance
    • Chen Y., Inobe I. Marks R., Gonnella P., Kuchroo V. K. and Weiner H. L. (1995) Peripheral deletion of antigen-reactive T cells in oral tolerance. Nature 376: 177-180
    • (1995) Nature , vol.376 , pp. 177-180
    • Chen, Y.1    Inobe, I.2    Marks, R.3    Gonnella, P.4    Kuchroo, V.K.5    Weiner, H.L.6
  • 41
    • 0035347115 scopus 로고    scopus 로고
    • Apoptosis of antigen-specific T cells induced by oral administration of antigen: Comparison of intestinal and non-intestinal immune organs
    • Ueda Y., Hachimura S., Somaya T., Hisatsune T. and Kaminogawa S. (2001) Apoptosis of antigen-specific T cells induced by oral administration of antigen: comparison of intestinal and non-intestinal immune organs. Biosci. Biotechnol. Biochem. 65: 1170-1174
    • (2001) Biosci. Biotechnol. Biochem. , vol.65 , pp. 1170-1174
    • Ueda, Y.1    Hachimura, S.2    Somaya, T.3    Hisatsune, T.4    Kaminogawa, S.5
  • 42
    • 0041845320 scopus 로고    scopus 로고
    • Proteome analysis reveals caspase activation in hyporesponsive CD4 T lymphocytes induced in vivo by the oral administration of antigen
    • Kaji T., Hachimura S., Ise W. and Kaminogawa S. (2003) Proteome analysis reveals caspase activation in hyporesponsive CD4 T lymphocytes induced in vivo by the oral administration of antigen. J. Biol. Chem. 278: 27836-27843
    • (2003) J. Biol. Chem. , vol.278 , pp. 27836-27843
    • Kaji, T.1    Hachimura, S.2    Ise, W.3    Kaminogawa, S.4
  • 43
    • 0026042008 scopus 로고
    • Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy
    • Whitacre C. C., Gienapp I. E., Orosz C. G. and Bitar D. M. (1991) Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy. J. Immunol. 147: 2155-2163
    • (1991) J. Immunol. , vol.147 , pp. 2155-2163
    • Whitacre, C.C.1    Gienapp, I.E.2    Orosz, C.G.3    Bitar, D.M.4
  • 44
    • 0027538442 scopus 로고
    • Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin
    • Melamed D. and A. Friedman (1993) Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin. Eur. J. Immunol. 23: 935-942
    • (1993) Eur. J. Immunol. , vol.23 , pp. 935-942
    • Melamed, D.1    Friedman, A.2
  • 45
    • 0028040873 scopus 로고
    • In vivo tolerization of Th1 lymphocytes following a single feeding with ovalbumin: Anergy in the absence of suppression
    • Melamed D. and A. Friedman (1994) In vivo tolerization of Th1 lymphocytes following a single feeding with ovalbumin: anergy in the absence of suppression. Eur. J. Immunol. 24: 1974-1981
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1974-1981
    • Melamed, D.1    Friedman, A.2
  • 46
    • 0030586668 scopus 로고    scopus 로고
    • Direct measurement of anergy of antigen-specific T cells following oral tolerance induction
    • Van Houten N. and Blake S. F. (1996) Direct measurement of anergy of antigen-specific T cells following oral tolerance induction. J. Immunol. 157: 1337-1341
    • (1996) J. Immunol. , vol.157 , pp. 1337-1341
    • Van Houten, N.1    Blake, S.F.2
  • 47
    • 0028237260 scopus 로고
    • Anergic T cells as suppressor cells in vitro
    • Lombardi G., Sidhu S., Batchelor R. and Lechler R. (1994) Anergic T cells as suppressor cells in vitro. Science 264: 1587-1589
    • (1994) Science , vol.264 , pp. 1587-1589
    • Lombardi, G.1    Sidhu, S.2    Batchelor, R.3    Lechler, R.4
  • 48
    • 0024524088 scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. II. Suppression of disease and in vitro immune responses is mediated by antigen-specific CD8+ T lymphocytes
    • Lider O., Santos L. M., Lee C. S., Higgins P. J. and Weiner H. L. (1989) Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. II. Suppression of disease and in vitro immune responses is mediated by antigen-specific CD8+ T lymphocytes. J. Immunol. 142: 748-752
    • (1989) J. Immunol. , vol.142 , pp. 748-752
    • Lider, O.1    Santos, L.M.2    Lee, C.S.3    Higgins, P.J.4    Weiner, H.L.5
  • 54
    • 0026542168 scopus 로고
    • Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering
    • Miller A., Lider O., Roberts A. B., Sporn M. B. and Weiner H. L. (1992) Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering. Proc. Natl. Acad. Sci. USA 89: 421-425
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 421-425
    • Miller, A.1    Lider, O.2    Roberts, A.B.3    Sporn, M.B.4    Weiner, H.L.5
  • 55
    • 0027941138 scopus 로고
    • Oral tolerance to myelin basic protein induces regulatory TGF-beta-secreting T cells in Peyer's patches of SJL mice
    • Santos L. M., al-Sabbagh A., Londono A. and Weiner H. L. (1994) Oral tolerance to myelin basic protein induces regulatory TGF-beta-secreting T cells in Peyer's patches of SJL mice. Cell. Immunol. 157: 439-447
    • (1994) Cell. Immunol. , vol.157 , pp. 439-447
    • Santos, L.M.1    Al-Sabbagh, A.2    Londono, A.3    Weiner, H.L.4
  • 56
    • 0034844841 scopus 로고    scopus 로고
    • Oral tolerance: Immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells
    • Weiner H. L. (2001) Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells. Microbes Infect. 3: 947-954
    • (2001) Microbes Infect. , vol.3 , pp. 947-954
    • Weiner, H.L.1
  • 57
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More questions than answers
    • + suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2: 389-400
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 58
    • 0037383757 scopus 로고    scopus 로고
    • Twenty-first century Foxp3
    • O'Garra A. and Vieira P. (2003) Twenty-first century Foxp3. Nat. Immunol. 4: 304-306
    • (2003) Nat. Immunol. , vol.4 , pp. 304-306
    • O'Garra, A.1    Vieira, P.2
  • 60
    • 0035399985 scopus 로고    scopus 로고
    • +CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
    • +CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J. Immunol. 167: 188-195
    • (2001) J. Immunol. , vol.167 , pp. 188-195
    • Thorstenson, K.M.1    Khoruts, A.2
  • 64
    • 3042594506 scopus 로고    scopus 로고
    • + regulatory T cells in children who have outgrown cow's milk allergy
    • + regulatory T cells in children who have outgrown cow's milk allergy. J. Exp. Med. 199: 1679-1688
    • (2004) J. Exp. Med. , vol.199 , pp. 1679-1688
    • Karlsson, M.R.1    Rugtveit, J.2    Brandtzaeg, P.3
  • 65
    • 0035801335 scopus 로고    scopus 로고
    • +) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • +) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J. Exp. Med. 194: 629-644
    • (2001) J. Exp. Med. , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 67
    • 0034613767 scopus 로고    scopus 로고
    • +) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • +) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192: 1213-1222
    • (2000) J. Exp. Med. , vol.192 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.H.5
  • 69
    • 0036732461 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
    • Akbari O., Freeman G. J., Meyer E. H., Greenfield E. A., Chang T. T., Sharpe A. H. et al. (2002) Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat. Med. 8: 1024-1032
    • (2002) Nat. Med. , vol.8 , pp. 1024-1032
    • Akbari, O.1    Freeman, G.J.2    Meyer, E.H.3    Greenfield, E.A.4    Chang, T.T.5    Sharpe, A.H.6
  • 70
    • 0036883901 scopus 로고    scopus 로고
    • Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora
    • Cong Y., Weaver C. T., Lazenby A. and Elson C. O. (2002) Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora. J. Immunol. 169: 6112-6119
    • (2002) J. Immunol. , vol.169 , pp. 6112-6119
    • Cong, Y.1    Weaver, C.T.2    Lazenby, A.3    Elson, C.O.4
  • 71
    • 0025318862 scopus 로고
    • Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function
    • Daynes R. A., Araneo B. A., Dowell T. A., Huang K. and D. Dudley (1990) Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function. J. Exp. Med. 171: 979-996
    • (1990) J. Exp. Med. , vol.171 , pp. 979-996
    • Daynes, R.A.1    Araneo, B.A.2    Dowell, T.A.3    Huang, K.4    Dudley, D.5
  • 72
    • 0037328869 scopus 로고    scopus 로고
    • Administration of exogenous interleukin-18 and interleukin-12 prevents the induction of oral tolerance
    • Eaton A. D., Xu D. and Garside P. (2003) Administration of exogenous interleukin-18 and interleukin-12 prevents the induction of oral tolerance. Immunology 108: 196-203
    • (2003) Immunology , vol.108 , pp. 196-203
    • Eaton, A.D.1    Xu, D.2    Garside, P.3
  • 73
    • 0033213958 scopus 로고    scopus 로고
    • Modulating dendritic cells to optimize mucosal immunization protocols
    • Williamson E., Westrich G. M. and Viney J. L. (1999) Modulating dendritic cells to optimize mucosal immunization protocols. J. Immunol. 163: 3668-3675
    • (1999) J. Immunol. , vol.163 , pp. 3668-3675
    • Williamson, E.1    Westrich, G.M.2    Viney, J.L.3
  • 74
    • 0034600789 scopus 로고    scopus 로고
    • Treatment of experimental (trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-betal plasmid: TGF-beta 1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor beta2 chain downregulation
    • Kitani A., Fuss I. J., Nakamura K., Schwartz O. M., Usui T. and Strober W. (2000) Treatment of experimental (trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-betal plasmid: TGF-beta 1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor beta2 chain downregulation. J. Exp. Med. 192: 41-52
    • (2000) J. Exp. Med. , vol.192 , pp. 41-52
    • Kitani, A.1    Fuss, I.J.2    Nakamura, K.3    Schwartz, O.M.4    Usui, T.5    Strober, W.6
  • 75
    • 0034991196 scopus 로고    scopus 로고
    • Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes
    • Slavin A. J., Maron R. and Weiner H. L. (2001) Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes. Int. Immunol. 13: 825-833
    • (2001) Int. Immunol. , vol.13 , pp. 825-833
    • Slavin, A.J.1    Maron, R.2    Weiner, H.L.3
  • 76
    • 0035879316 scopus 로고    scopus 로고
    • The Peyer's patch microenvironment suppresses T cell responses to chemokines and other stimuli
    • Kellermann S. A. and McEvoyv L. M. (2001) The Peyer's patch microenvironment suppresses T cell responses to chemokines and other stimuli. J. Immunol. 167: 682-690
    • (2001) J. Immunol. , vol.167 , pp. 682-690
    • Kellermann, S.A.1    McEvoyv, L.M.2
  • 77
    • 0026572708 scopus 로고
    • Selective induction of Th2 cells in murine Peyer's patches by oral immunization
    • Xu-Amano J., Aicher W. K., Taguchi T., Kiyono H. and McGhee J. R. (1992) Selective induction of Th2 cells in murine Peyer's patches by oral immunization. Int. Immunol. 4: 433-445
    • (1992) Int. Immunol. , vol.4 , pp. 433-445
    • Xu-Amano, J.1    Aicher, W.K.2    Taguchi, T.3    Kiyono, H.4    McGhee, J.R.5
  • 78
    • 0037097777 scopus 로고    scopus 로고
    • Murine Peyer's patches favor development of an IL-10-secreting, regulatory T cell population
    • Jump R. L. and Levine A. D. (2002) Murine Peyer's patches favor development of an IL-10-secreting, regulatory T cell population. J. Immunol. 168: 6113-6119
    • (2002) J. Immunol. , vol.168 , pp. 6113-6119
    • Jump, R.L.1    Levine, A.D.2
  • 79
    • 0036530016 scopus 로고    scopus 로고
    • +) anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity
    • +) anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity. Blood 99: 2468-2476
    • (2002) Blood , vol.99 , pp. 2468-2476
    • Steinbrink, K.1    Graulich, E.2    Kubsch, S.3    Knop, J.4    Enk, A.H.5
  • 86
    • 0019984839 scopus 로고
    • Lipopolysaccharide (LPS) regulation of the immune response: LPS converts germfree mice to sensitivity to oral tolerance induction
    • Wannemuehler M. J., Kiyono H., Babb J. L., Michalek S. M. and McGhee J. R. (1982) Lipopolysaccharide (LPS) regulation of the immune response: LPS converts germfree mice to sensitivity to oral tolerance induction. J. Immunol. 129: 959-965
    • (1982) J. Immunol. , vol.129 , pp. 959-965
    • Wannemuehler, M.J.1    Kiyono, H.2    Babb, J.L.3    Michalek, S.M.4    McGhee, J.R.5
  • 87
    • 0019991078 scopus 로고
    • Lipopolysaccharide (LPS) regulation of the immune response: LPS influence on oral tolerance induction
    • Michalek S. M., Kiyono H., Wannemuehler M. J., Mosteller L. M. and McGhee J. R. (1982) Lipopolysaccharide (LPS) regulation of the immune response: LPS influence on oral tolerance induction. J. Immunol. 128: 1992-1998
    • (1982) J. Immunol. , vol.128 , pp. 1992-1998
    • Michalek, S.M.1    Kiyono, H.2    Wannemuehler, M.J.3    Mosteller, L.M.4    McGhee, J.R.5
  • 88
    • 0031571230 scopus 로고    scopus 로고
    • The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction
    • Sudo N., Sawamura S., Tanaka K., Aiba Y., Kubo C. and Koga Y. (1997) The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J. Immunol. 159: 1739-1745
    • (1997) J. Immunol. , vol.159 , pp. 1739-1745
    • Sudo, N.1    Sawamura, S.2    Tanaka, K.3    Aiba, Y.4    Kubo, C.5    Koga, Y.6
  • 89
    • 0023687225 scopus 로고
    • Effect of the gastro-intestinal microflora on induction and maintenance of oral tolerance to ovalbumin in C3H/HeJ mice
    • Moreau M. C. and Corthier G. (1988) Effect of the gastro-intestinal microflora on induction and maintenance of oral tolerance to ovalbumin in C3H/HeJ mice. Infect. Immun. 56: 2766-2768
    • (1988) Infect. Immun. , vol.56 , pp. 2766-2768
    • Moreau, M.C.1    Corthier, G.2
  • 90
    • 0025666659 scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. III. Synergistic effect of lipopolysaccharide
    • Khoury S. J., Lider O., al-Sabbagli A. and Weiner H. L. (1990) Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. III. Synergistic effect of lipopolysaccharide. Cell. Immunol. 131: 302-310
    • (1990) Cell. Immunol. , vol.131 , pp. 302-310
    • Khoury, S.J.1    Lider, O.2    Al-Sabbagli, A.3    Weiner, H.L.4
  • 91
    • 0030734860 scopus 로고    scopus 로고
    • Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes
    • Beatty W. L. and Sansonetti P. J. (1997) Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes. Infect. Immun. 65: 4395-4404
    • (1997) Infect. Immun. , vol.65 , pp. 4395-4404
    • Beatty, W.L.1    Sansonetti, P.J.2
  • 92
    • 0038185270 scopus 로고    scopus 로고
    • Prophylaxis of pouchitis onset with probiotic therapy: A double-blind, placebo-controlled trial
    • Gionchetti P., Rizzello F., Helwig U., Venturi A., Lammers K. M., Brigidi P. et al. (2003) Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. Gastroenterology 124: 1202-1209
    • (2003) Gastroenterology , vol.124 , pp. 1202-1209
    • Gionchetti, P.1    Rizzello, F.2    Helwig, U.3    Venturi, A.4    Lammers, K.M.5    Brigidi, P.6
  • 94
    • 0037450746 scopus 로고    scopus 로고
    • Control of immune responses by naturally arising CD4+ regulatory T cells that express toll-like receptors
    • Sakaguchi S. (2003) Control of immune responses by naturally arising CD4+ regulatory T cells that express toll-like receptors. J. Exp. Med. 197: 397-401
    • (2003) J. Exp. Med. , vol.197 , pp. 397-401
    • Sakaguchi, S.1
  • 95
    • 0037450804 scopus 로고    scopus 로고
    • Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide
    • Caramalho I., Lopes-Carvalho T., Ostler D., Zelenay S., Haury M. and Demengeot J. (2003) Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide. J. Exp. Med. 197: 403-411
    • (2003) J. Exp. Med. , vol.197 , pp. 403-411
    • Caramalho, I.1    Lopes-Carvalho, T.2    Ostler, D.3    Zelenay, S.4    Haury, M.5    Demengeot, J.6
  • 96
    • 1542409922 scopus 로고    scopus 로고
    • Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells
    • Netea M. G., Sutmuller R., Hermann C., Van der Graaf C. A., Van der Meer J. W., van Krieken J. H. et al. (2004) Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells. J. Immunol. 172: 3712-3718
    • (2004) J. Immunol. , vol.172 , pp. 3712-3718
    • Netea, M.G.1    Sutmuller, R.2    Hermann, C.3    Van Der Graaf, C.A.4    Van Der Meer, J.W.5    Van Krieken, J.H.6
  • 97
    • 0036136282 scopus 로고    scopus 로고
    • Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells
    • Christensen H. R., Frokiaer H. and Pestka J. J. (2002) Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells. J. Immunol. 168: 171-178
    • (2002) J. Immunol. , vol.168 , pp. 171-178
    • Christensen, H.R.1    Frokiaer, H.2    Pestka, J.J.3
  • 98
    • 0034968127 scopus 로고    scopus 로고
    • +) T cells with low proliferative capacity that produce transforming growth factor beta and interleukin-10
    • +) T cells with low proliferative capacity that produce transforming growth factor beta and interleukin-10. Clin. Diagn. Lab. Immunol. 8: 695-701
    • (2001) Clin. Diagn. Lab. Immunol. , vol.8 , pp. 695-701
    • Von Der Weid, T.1    Bulliard, C.2    Schiffrin, E.J.3
  • 99
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman C., Mauze S., Leach M. W., Coffmanv and Powrie F. (1999) An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190: 995-1004
    • (1999) J. Exp. Med. , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffmanv4    Powrie, F.5
  • 101
    • 0242580070 scopus 로고    scopus 로고
    • + regulatory T cells cure murine colitis: The role of IL-10, TGF-beta and CTLA4
    • + regulatory T cells cure murine colitis: the role of IL-10, TGF-beta and CTLA4. J. Immunol. 171: 5012-5017
    • (2003) J. Immunol. , vol.171 , pp. 5012-5017
    • Liu, H.1    Hu, B.2    Xu, D.3    Liew, F.Y.4
  • 103
    • 0028945688 scopus 로고
    • Anti-IL-10 treatment does not block either the induction or the maintenance of orally induced tolerance to OVA
    • Aroeira L. S., Cardillo F., De Albuquerque D. A., Vaz N. M. and Mengel J. (1995) Anti-IL-10 treatment does not block either the induction or the maintenance of orally induced tolerance to OVA. Scand. J. Immunol. 41: 319-323
    • (1995) Scand. J. Immunol. , vol.41 , pp. 319-323
    • Aroeira, L.S.1    Cardillo, F.2    De Albuquerque, D.A.3    Vaz, N.M.4    Mengel, J.5
  • 106
    • 0036773635 scopus 로고    scopus 로고
    • CTLA-4 expression on antigen-specific cells but not IL-10 secretion is required for oral tolerance
    • Fowler S. and Powrie F. (2002) CTLA-4 expression on antigen-specific cells but not IL-10 secretion is required for oral tolerance. Eur. J. Immunol. 32: 2997-3006
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2997-3006
    • Fowler, S.1    Powrie, F.2
  • 107
    • 0037080032 scopus 로고    scopus 로고
    • The interrelated roles of TGF-beta and IL-10 in the regulation of experimental colitis
    • Fuss I. J., Boirivant M., Lacy B. and Strober W. (2002) The interrelated roles of TGF-beta and IL-10 in the regulation of experimental colitis. J. Immunol. 168: 900-908
    • (2002) J. Immunol. , vol.168 , pp. 900-908
    • Fuss, I.J.1    Boirivant, M.2    Lacy, B.3    Strober, W.4
  • 108
    • 0035879091 scopus 로고    scopus 로고
    • Regulation of TGF-beta response during T cell activation is modulated by IL-10
    • Cottrez F. and Groux H. (2001) Regulation of TGF-beta response during T cell activation is modulated by IL-10. J. Immunol. 167: 773-778
    • (2001) J. Immunol. , vol.167 , pp. 773-778
    • Cottrez, F.1    Groux, H.2
  • 109
    • 0142219250 scopus 로고    scopus 로고
    • Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis
    • Kitani A., Fuss I., Nakamura K., Kumaki F., Usui T. and Strober W. (2003) Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis. J. Exp. Med. 198: 1179-1188
    • (2003) J. Exp. Med. , vol.198 , pp. 1179-1188
    • Kitani, A.1    Fuss, I.2    Nakamura, K.3    Kumaki, F.4    Usui, T.5    Strober, W.6
  • 110
    • 0037099733 scopus 로고    scopus 로고
    • +) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells
    • +) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells. J. Exp. Med. 196: 247-253
    • (2002) J. Exp. Med. , vol.196 , pp. 247-253
    • Dieckmann, D.1    Bruett, C.H.2    Ploettner, H.3    Lutz, M.B.4    Schuler, G.5
  • 112
    • 0041331731 scopus 로고    scopus 로고
    • Infectious nickel tolerance: A reciprocal interplay of tolerogenic APCs and T suppressor cells that is driven by immunization
    • Roelofs-Haarhuis K., Wu X., Nowak M., Fang M., Artik S. and Gleichmann E. (2003) Infectious nickel tolerance: a reciprocal interplay of tolerogenic APCs and T suppressor cells that is driven by immunization. J. Immunol. 171: 2863-2872
    • (2003) J. Immunol. , vol.171 , pp. 2863-2872
    • Roelofs-Haarhuis, K.1    Wu, X.2    Nowak, M.3    Fang, M.4    Artik, S.5    Gleichmann, E.6
  • 113
    • 0033566743 scopus 로고    scopus 로고
    • Insulin in oral immune 'tolerance': A one-amino acid change in the B chain makes the difference
    • Homann D., Dyrberg T., Petersen J., Oldstone M. B. and von Herrath M. G. (1999) Insulin in oral immune 'tolerance': a one-amino acid change in the B chain makes the difference. J. Immunol. 163: 1833-1838
    • (1999) J. Immunol. , vol.163 , pp. 1833-1838
    • Homann, D.1    Dyrberg, T.2    Petersen, J.3    Oldstone, M.B.4    Von Herrath, M.G.5
  • 114
    • 2942655175 scopus 로고    scopus 로고
    • 'Educated' dendritic cells act as messengers from memory to naive T helper cells
    • Alpan O., Bachelder E., Isil E., Arnheiter H. and Matzinger P. (2004) 'Educated' dendritic cells act as messengers from memory to naive T helper cells. Nat. Immunol. 5: 615-622
    • (2004) Nat. Immunol. , vol.5 , pp. 615-622
    • Alpan, O.1    Bachelder, E.2    Isil, E.3    Arnheiter, H.4    Matzinger, P.5
  • 115
    • 0032526346 scopus 로고    scopus 로고
    • Expanding dendritic cells in vivo enhances the induction of oral tolerance
    • Viney J. L., Mowat A. M., O'Malley J. M., Williamson E. and Fanger N. A. (1998) Expanding dendritic cells in vivo enhances the induction of oral tolerance. J. Immunol. 160: 5815-5825
    • (1998) J. Immunol. , vol.160 , pp. 5815-5825
    • Viney, J.L.1    Mowat, A.M.2    O'Malley, J.M.3    Williamson, E.4    Fanger, N.A.5
  • 116
    • 0034890907 scopus 로고    scopus 로고
    • Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
    • Akbari O., DeKruyff R. H. and Umetsu D. T. (2001) Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat. Immunol. 2: 725-731
    • (2001) Nat. Immunol. , vol.2 , pp. 725-731
    • Akbari, O.1    DeKruyff, R.H.2    Umetsu, D.T.3
  • 117
    • 0030067796 scopus 로고    scopus 로고
    • Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyer's patch
    • Kelsall B. L. and Strober W. (1996) Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyer's patch. J. Exp. Med. 183: 237-247
    • (1996) J. Exp. Med. , vol.183 , pp. 237-247
    • Kelsall, B.L.1    Strober, W.2
  • 118
    • 0035871705 scopus 로고    scopus 로고
    • +, and double-negative Peyer's patch dendritic cells
    • +, and double-negative Peyer's patch dendritic cells. J. Immunol. 166: 4884-4890
    • (2001) J. Immunol. , vol.166 , pp. 4884-4890
    • Iwasaki, A.1    Kelsall, B.L.2
  • 119
    • 0034678392 scopus 로고    scopus 로고
    • Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3alpha, MIP-3beta, and secondary lymphoid organ chemokine
    • Iwasaki A. and Kelsall B. L. (2000) Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3alpha, MIP-3beta, and secondary lymphoid organ chemokine. J. Exp. Med. 191: 1381-1394
    • (2000) J. Exp. Med. , vol.191 , pp. 1381-1394
    • Iwasaki, A.1    Kelsall, B.L.2
  • 120
    • 0346366990 scopus 로고    scopus 로고
    • Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody
    • Asselin-Paturel C., Brizard G., Pin J. J., Briere F. and Trinchieri G. (2003) Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J. Immunol. 171: 6466-6477
    • (2003) J. Immunol. , vol.171 , pp. 6466-6477
    • Asselin-Paturel, C.1    Brizard, G.2    Pin, J.J.3    Briere, F.4    Trinchieri, G.5
  • 121
    • 0037391351 scopus 로고    scopus 로고
    • + DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties
    • + DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties. Immunology 108: 481-492
    • (2003) Immunology , vol.108 , pp. 481-492
    • Bilsborough, J.1    George, T.C.2    Norment, A.3    Viney, J.L.4
  • 122
    • 0033584234 scopus 로고    scopus 로고
    • Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells
    • Iwasaki A. and Kelsall B. L. (1999) Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J. Exp. Med. 190: 229-239
    • (1999) J. Exp. Med. , vol.190 , pp. 229-239
    • Iwasaki, A.1    Kelsall, B.L.2
  • 123
    • 0036784632 scopus 로고    scopus 로고
    • Regulation of mucosal dendritic cell function by receptor activator of NF-κB (RANK)/RANK ligand interactions: Impact on tolerance induction
    • Williamson E., Bilsborough J. M. and Viney J. L. (2002) Regulation of mucosal dendritic cell function by receptor activator of NF-κB (RANK)/RANK ligand interactions: impact on tolerance induction. J. Immunol. 169: 3606-3612
    • (2002) J. Immunol. , vol.169 , pp. 3606-3612
    • Williamson, E.1    Bilsborough, J.M.2    Viney, J.L.3
  • 124
    • 0037987977 scopus 로고    scopus 로고
    • Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
    • Wakkach A., Fournier N., Brun V., Breittmayer J. P., Cottrez F. and Groux H. (2003) Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18: 605-617
    • (2003) Immunity , vol.18 , pp. 605-617
    • Wakkach, A.1    Fournier, N.2    Brun, V.3    Breittmayer, J.P.4    Cottrez, F.5    Groux, H.6
  • 127
    • 0037237628 scopus 로고    scopus 로고
    • Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: Dependency on antigen dose and differential toll-like receptor ligation
    • Boonstra A., Asselin-Paturel C., Gilliet M., Crain C., Trinchieri G., Liu Y. J. et al. (2003) Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J. Exp. Med. 197: 101-109
    • (2003) J. Exp. Med. , vol.197 , pp. 101-109
    • Boonstra, A.1    Asselin-Paturel, C.2    Gilliet, M.3    Crain, C.4    Trinchieri, G.5    Liu, Y.J.6
  • 128
    • 0037128654 scopus 로고    scopus 로고
    • Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells
    • Gilliet M. and Liu Y. J. (2002) Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J. Exp. Med. 195: 695-704
    • (2002) J. Exp. Med. , vol.195 , pp. 695-704
    • Gilliet, M.1    Liu, Y.J.2
  • 131
    • 0037090313 scopus 로고    scopus 로고
    • Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses
    • Mellor A. L., Keskin D. B., Johnson T., Chandler P. and Munn D. H. (2002) Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses. J. Immunol. 168: 3771-3776
    • (2002) J. Immunol. , vol.168 , pp. 3771-3776
    • Mellor, A.L.1    Keskin, D.B.2    Johnson, T.3    Chandler, P.4    Munn, D.H.5
  • 133
    • 0038215374 scopus 로고    scopus 로고
    • Tolerance, DCs and tryptophan: Much ado about IDO
    • Grohmann U., Fallarino F. and Puccetti P. (2003) Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol. 24: 242-248
    • (2003) Trends Immunol. , vol.24 , pp. 242-248
    • Grohmann, U.1    Fallarino, F.2    Puccetti, P.3
  • 135
    • 18544364477 scopus 로고    scopus 로고
    • Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase
    • Munn D. H., Sharma M. D., Lee J. R., Jhaver K. G., Johnson T. S., Keskin D. B. et al. (2002) Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science 297: 1867-1870
    • (2002) Science , vol.297 , pp. 1867-1870
    • Munn, D.H.1    Sharma, M.D.2    Lee, J.R.3    Jhaver, K.G.4    Johnson, T.S.5    Keskin, D.B.6
  • 136
    • 0037270978 scopus 로고    scopus 로고
    • Hepatic T cells and liver tolerance
    • Crispe I. N. (2003) Hepatic T cells and liver tolerance. Nat. Rev. Immunol. 3: 51-62
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 51-62
    • Crispe, I.N.1
  • 137
    • 0014200984 scopus 로고
    • Hepatic suppression of sensitization to antigen absorbed into the portal system
    • Cantor H. M. and Dumont A. E. (1967) Hepatic suppression of sensitization to antigen absorbed into the portal system. Nature 215: 744-745
    • (1967) Nature , vol.215 , pp. 744-745
    • Cantor, H.M.1    Dumont, A.E.2
  • 138
    • 0028070723 scopus 로고
    • Intestinal venous drainage through the liver is a prerequisite for oral tolerance induction
    • Yang R., Liu Q., Grosfeld J. L. and Pescovitz M. D. (1994) Intestinal venous drainage through the liver is a prerequisite for oral tolerance induction. J. Pediatr. Surg. 29: 1145-1148
    • (1994) J. Pediatr. Surg. , vol.29 , pp. 1145-1148
    • Yang, R.1    Liu, Q.2    Grosfeld, J.L.3    Pescovitz, M.D.4
  • 141
    • 1642495750 scopus 로고    scopus 로고
    • Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition
    • Pillarisetty V. G., Shah A. B., Miller G., Bleier J. I. and De-Matteo R. P. (2004) Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition. J. Immunol. 172: 1009-1017
    • (2004) J. Immunol. , vol.172 , pp. 1009-1017
    • Pillarisetty, V.G.1    Shah, A.B.2    Miller, G.3    Bleier, J.I.4    De-Matteo, R.P.5
  • 142
    • 0037371123 scopus 로고    scopus 로고
    • Heterogeneity of dendritic cells in the mouse liver: Identification and characterization of four distinct populations
    • Lian Z. X., Okada T., He X. S., Kita H., Liu Y. J., Ansari A. A. et al. (2003) Heterogeneity of dendritic cells in the mouse liver: identification and characterization of four distinct populations. J. Immunol. 170: 2323-2330
    • (2003) J. Immunol. , vol.170 , pp. 2323-2330
    • Lian, Z.X.1    Okada, T.2    He, X.S.3    Kita, H.4    Liu, Y.J.5    Ansari, A.A.6
  • 143
    • 0036201121 scopus 로고    scopus 로고
    • CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells
    • Homann D., Jahreis A., Wolfe T., Hughes A., Coon B., van Stipdonk M. J. et al. (2002) CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells. Immunity 16: 403-415
    • (2002) Immunity , vol.16 , pp. 403-415
    • Homann, D.1    Jahreis, A.2    Wolfe, T.3    Hughes, A.4    Coon, B.5    Van Stipdonk, M.J.6
  • 144
    • 2942620546 scopus 로고    scopus 로고
    • Therapeutic potential of oral tolerance
    • Mayer L. and Shao L. (2004) Therapeutic potential of oral tolerance. Nat. Rev. Immunol. 4: 407-419
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 407-419
    • Mayer, L.1    Shao, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.