Binding of Ikaros to the λ5 promoter silences transcription through a mechanism that does not require heterochromatin formation

EMBO Journal

Volumn 20, Issue 11, 2001, Pages 2812-2822

  Sabbattini, Pierangela ^a   Lundgren, Mats ^a,b   Georgiou, Andrew ^a   Chow, Cheok Man ^a   Warnes, Gary ^a   Dillon, Niall ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b Box 853   (Sweden)

Author keywords

5 promoter; Heterochromatin; Ikaros family; Transcription silencing

Indexed keywords

DNA; DNA BINDING PROTEIN; IKAROS TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; IMMUNOGLOBULIN LAMBDA CHAIN; TRANSCRIPTION FACTOR; ZFPN1A1 PROTEIN, MOUSE; ZINC FINGER PROTEIN; ZNFN1A1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE ACTIVATION; BINDING SITE; GENE EXPRESSION; GENE SILENCING; HETEROCHROMATIN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; ANIMAL; B LYMPHOCYTE; C57BL MOUSE; CELL LINE; CHEMISTRY; GENETIC TRANSCRIPTION; GENETICS; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOLOGY; LIVER; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PRENATAL DEVELOPMENT; SPLEEN; TRANSGENIC MOUSE; ULTRASTRUCTURE;

ANIMALS; B-LYMPHOCYTES; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA-BINDING PROTEINS; GENE SILENCING; HEMATOPOIETIC STEM CELLS; HETEROCHROMATIN; HUMANS; IKAROS TRANSCRIPTION FACTOR; IMMUNOGLOBULIN LAMBDA-CHAINS; LIVER; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; ZINC FINGERS;

EID: 0035355509     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.11.2812     Document Type: Article

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