-
1
-
-
0020216124
-
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
-
Nusse, R. & Varmus, H. E. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell 31, 99-109 (1982).
-
(1982)
Cell
, vol.31
, pp. 99-109
-
-
Nusse, R.1
Varmus, H.E.2
-
2
-
-
0036534586
-
TCF transcription factors, mediators of Wnt-signaling in development and cancer
-
van Noort, M. & Clevers, H. TCF transcription factors, mediators of Wnt-signaling in development and cancer. Dev. Biol. 244, 1-8 (2002).
-
(2002)
Dev. Biol.
, vol.244
, pp. 1-8
-
-
Van Noort, M.1
Clevers, H.2
-
3
-
-
0035257660
-
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation
-
Bhardwaj, G. et al. Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nature Immunol. 2, 172-180 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 172-180
-
-
Bhardwaj, G.1
-
4
-
-
0033526067
-
Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells
-
Bhatia, M. et al. Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. J. Exp. Med. 189, 1139-1148 (1999).
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1139-1148
-
-
Bhatia, M.1
-
5
-
-
0032101002
-
The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells
-
Vamum-Finney, B. et al. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells. Blood 91, 4084-4091 (1998).
-
(1998)
Blood
, vol.91
, pp. 4084-4091
-
-
Vamum-Finney, B.1
-
6
-
-
0034727104
-
LDL-receptor-related proteins in Wnt signal transduction
-
Tamai, K. et al. LDL-receptor-related proteins in Wnt signal transduction. Nature 407, 530-535 (2000).
-
(2000)
Nature
, vol.407
, pp. 530-535
-
-
Tamai, K.1
-
7
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
-
Mao, J. et al. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol. Cell 7, 801-809 (2001).
-
(2001)
Mol. Cell
, vol.7
, pp. 801-809
-
-
Mao, J.1
-
8
-
-
0035902050
-
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
-
Mao, B. et al. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411, 321-325 (2001).
-
(2001)
Nature
, vol.411
, pp. 321-325
-
-
Mao, B.1
-
9
-
-
2442663185
-
Specificity of WNT-receptor interactions
-
Hsieh, J. C. Specificity of WNT-receptor interactions. Front. Biosci. 9, 1333-1338 (2004).
-
(2004)
Front. Biosci.
, vol.9
, pp. 1333-1338
-
-
Hsieh, J.C.1
-
10
-
-
2442708165
-
Frizzleds: New members of the superfamily of G-protein-coupted receptors
-
Malbon, C. C. Frizzleds: new members of the superfamily of G-protein-coupted receptors. Front. Biosci. 9, 1048-1058 (2004).
-
(2004)
Front. Biosci.
, vol.9
, pp. 1048-1058
-
-
Malbon, C.C.1
-
11
-
-
2442713063
-
WNT-frizzled signaling via cyclic GMP
-
Wang, H. Y. WNT-frizzled signaling via cyclic GMP. Front. Biosci. 9, 1043-1047 (2004).
-
(2004)
Front. Biosci.
, vol.9
, pp. 1043-1047
-
-
Wang, H.Y.1
-
12
-
-
3843057846
-
The WNT/calcium pathway; biochemical mediators, tools and future requirements
-
Kuhl, M. The WNT/calcium pathway; biochemical mediators, tools and future requirements. Front. Biosci. 9, 967-974 (2004).
-
(2004)
Front. Biosci.
, vol.9
, pp. 967-974
-
-
Kuhl, M.1
-
13
-
-
1642430935
-
Wnt breakers in colon cancer
-
Clevers, H. Wnt breakers in colon cancer. Cancer Cell 5, 5-6 (2004).
-
(2004)
Cancer Cell
, vol.5
, pp. 5-6
-
-
Clevers, H.1
-
14
-
-
1642499389
-
Wnt-frizzled signaling to G-protein-coupled effectors
-
Wang, H. Y. & Malbon, C. C. Wnt-frizzled signaling to G-protein-coupled effectors. Cell. Mol. Life Sci. 61, 69-75 (2004).
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 69-75
-
-
Wang, H.Y.1
Malbon, C.C.2
-
15
-
-
0024451982
-
The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species
-
Ozawa, M., Baribault, H. & Kemler, R. The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J. 8, 1711-1717 (1989).
-
(1989)
EMBO J.
, vol.8
, pp. 1711-1717
-
-
Ozawa, M.1
Baribault, H.2
Kemler, R.3
-
16
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β
-
Behrens, J. et al. Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β. Science 280, 596-599 (1998).
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
-
17
-
-
1942537708
-
The significance of the Wnt pathway in the pathology of human cancers
-
Karim, R., Tse, G., Putti, T., Scolyer, R. & Lee, S. The significance of the Wnt pathway in the pathology of human cancers. Pathology 36, 120-128 (2004).
-
(2004)
Pathology
, vol.36
, pp. 120-128
-
-
Karim, R.1
Tse, G.2
Putti, T.3
Scolyer, R.4
Lee, S.5
-
18
-
-
0346655150
-
The ins and outs of Wingless signaling
-
Seto, E. S. & Bellen, H. J. The ins and outs of Wingless signaling. Trends Cell Biol. 14, 45-53 (2004).
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 45-53
-
-
Seto, E.S.1
Bellen, H.J.2
-
19
-
-
1542347695
-
Convergence of Wnt, β-catenin, and cadherin pathways
-
Nelson, W. J. & Nusse, R. Convergence of Wnt, β-catenin, and cadherin pathways. Science 303, 1483-1487 (2004).
-
(2004)
Science
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
20
-
-
0037309239
-
You Wnt some, you lose some: Oncogenes in the Wnt signaling pathway
-
van Es, J. H., Barker, N. & Clevers, H. You Wnt some, you lose some: oncogenes in the Wnt signaling pathway. Curr. Opin. Genet. Dev. 13, 28-33 (2003).
-
(2003)
Curr. Opin. Genet. Dev.
, vol.13
, pp. 28-33
-
-
Van Es, J.H.1
Barker, N.2
Clevers, H.3
-
21
-
-
0032497485
-
The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
-
Roose, J. et al. The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors. Nature 395, 608-612 (1998).
-
(1998)
Nature
, vol.395
, pp. 608-612
-
-
Roose, J.1
-
22
-
-
0035801499
-
The chromatin remodelling factor Brg-1 interacts with β-catenin to promote target gene activation
-
Barker, N. et al. The chromatin remodelling factor Brg-1 interacts with β-catenin to promote target gene activation. EMBO J. 20, 4935-4943 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 4935-4943
-
-
Barker, N.1
-
23
-
-
0242515751
-
Chibby, a nuclear β-catenin-associated antagonist of the Wnt/Wingless pathway
-
Takemaru, K. et al. Chibby, a nuclear β-catenin-associated antagonist of the Wnt/Wingless pathway. Nature 422, 905-909 (2003).
-
(2003)
Nature
, vol.422
, pp. 905-909
-
-
Takemaru, K.1
-
24
-
-
0036754604
-
ICAT inhibits β-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p 300 using independent structural modules
-
Daniels, D. L. & Weis, W. I. ICAT inhibits β-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules. Mol. Cell 10, 573-584 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 573-584
-
-
Daniels, D.L.1
Weis, W.I.2
-
25
-
-
0037023584
-
Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear β-catenin-TCF complex
-
Kramps, T. et al. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear β-catenin-TCF complex. Cell 109,47-60 (2002).
-
(2002)
Cell
, vol.109
, pp. 47-60
-
-
Kramps, T.1
-
26
-
-
1242317058
-
Pygopus residues required for its binding to Legless are critical for transcription and development
-
Townsley, F. M., Thompson, B. & Bienz, M. Pygopus residues required for its binding to Legless are critical for transcription and development. J. Biol. Chem. 279, 5177-5183 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5177-5183
-
-
Townsley, F.M.1
Thompson, B.2
Bienz, M.3
-
27
-
-
3242706980
-
Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activator function
-
Townsley, F. M., Cliffe, A. & Bienz, M. Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activator function. Nature Cell Biol. 6, 626-633 (2004). References 25-27 show the importance of LGS and PYGO for transcriptional activation of the β-catenin-TCF complex.
-
(2004)
Nature Cell Biol.
, vol.6
, pp. 626-633
-
-
Townsley, F.M.1
Cliffe, A.2
Bienz, M.3
-
28
-
-
1842430786
-
A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes
-
Thompson, B. J. A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes. Curr. Biol. 14, 458-466 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 458-466
-
-
Thompson, B.J.1
-
29
-
-
0030989287
-
A role for the Wnt gene family in hematopoiesis: Expansion of multilineage progenitor cells
-
Austin, T. W., Solar, G. P., Ziegler, F. C., Liem, L. & Matthews, W. A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells. Blood 89, 3624-3635 (1997).
-
(1997)
Blood
, vol.89
, pp. 3624-3635
-
-
Austin, T.W.1
Solar, G.P.2
Ziegler, F.C.3
Liem, L.4
Matthews, W.5
-
30
-
-
0032212190
-
Role of members of the Wnt gene family in human hematopoiesis
-
van den Berg, D. J., Sharma, A. K., Bruno, E. & Hoffman, R. Role of members of the Wnt gene family in human hematopoiesis. Blood 92, 3189-3202 (1998).
-
(1998)
Blood
, vol.92
, pp. 3189-3202
-
-
Van Den Berg, D.J.1
Sharma, A.K.2
Bruno, E.3
Hoffman, R.4
-
31
-
-
0037452998
-
Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo
-
Murdoch, B. et al. Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo. Proc. Natl Acad. Sci. USA 100, 3422-3427 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3422-3427
-
-
Murdoch, B.1
-
32
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
Reya, T. et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 423, 409-414 (2003).
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
-
33
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert, K. et al. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423, 448-452 (2003). References 32 and 33 implicate WNT signalling in the self-renewal of HSCs. Reference 33 mainly describes the purification of biologically active recombinant WNT3A protein, using HSC proliferation as a read-out
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
-
34
-
-
0028985161
-
An HMG-box-containing T-cell factor required for thymocyte differentiation
-
Verbeek, S. et al. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature 374, 70-74 (1995). This paper describes the two types of TCF1-deficient mice and their thymic phenotypes.
-
(1995)
Nature
, vol.374
, pp. 70-74
-
-
Verbeek, S.1
-
35
-
-
0032532301
-
Critical involvement of Tcf-1 in expansion of thymocytes
-
Schilham, M. W. et al. Critical involvement of Tcf-1 in expansion of thymocytes. J. Immunol. 161, 3984-3991 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 3984-3991
-
-
Schilham, M.W.1
-
36
-
-
0033013369
-
Nuclear localization and formation of β-catenin-lymphoid enhancer factor 1 complexes are not sufficient for activation of gene expression
-
Prieve, M. G. & Waterman, M. L. Nuclear localization and formation of β-catenin-lymphoid enhancer factor 1 complexes are not sufficient for activation of gene expression. Mol. Cell. Biol. 19, 4503-4515 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4503-4515
-
-
Prieve, M.G.1
Waterman, M.L.2
-
37
-
-
0025794148
-
LHF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor-α enhancer function
-
Travis, A., Amsterdam, A., Belanger, C. & Grosschedl, R. LHF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor-α enhancer function. Genes Dev. 5, 880-894 (1991).
-
(1991)
Genes Dev.
, vol.5
, pp. 880-894
-
-
Travis, A.1
Amsterdam, A.2
Belanger, C.3
Grosschedl, R.4
-
38
-
-
0027945654
-
Development of several organs that require inductive epithelial- mesenchymal interactions is impaired in LEF-1-deficient mice
-
van Genderen, C. et al. Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev. 8, 2691-2703 (1994).
-
(1994)
Genes Dev.
, vol.8
, pp. 2691-2703
-
-
Van Genderen, C.1
-
39
-
-
0031883962
-
Redundant regulation of T cell differentiation and TCRα gene expression by the transcription factors LEF-1 and TCF-1
-
Okamura, R. M. et al. Redundant regulation of T cell differentiation and TCRα gene expression by the transcription factors LEF-1 and TCF-1. Immunity 8, 11-20 (1998). This paper describes the thymic phenotype of mice that are deficient in both TCF1 and LEF1.
-
(1998)
Immunity
, vol.8
, pp. 11-20
-
-
Okamura, R.M.1
-
41
-
-
0030067337
-
Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties
-
Van de Wetering, M., Castrop, J., Korinek, V. & Clevers, H. Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties. Mol. Cell. Biol. 16, 745-752 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 745-752
-
-
Van De Wetering, M.1
Castrop, J.2
Korinek, V.3
Clevers, H.4
-
43
-
-
0035134933
-
Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription
-
Steal, F. J. et al. Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription. Eur. J. Immunol. 31, 285-293 (2001).
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 285-293
-
-
Steal, F.J.1
-
44
-
-
0041967288
-
Thymic epithelial cells provide WNT signals to developing thymocytes
-
Pongracz, J., Hare, K., Harman, B., Anderson, G. & Jenkinson, E. J. Thymic epithelial cells provide WNT signals to developing thymocytes. Eur. J. Immunol. 33, 1949-1956 (2003).
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 1949-1956
-
-
Pongracz, J.1
Hare, K.2
Harman, B.3
Anderson, G.4
Jenkinson, E.J.5
-
45
-
-
0036232701
-
Wnt-1 and Wnt-4 regulate thymic cellularity
-
Mulroy, T., McMahon, J. A., Burakoff, S. J., McMahon, A. P. & Sen, J. Wnt-1 and Wnt-4 regulate thymic cellularity. Eur. J. Immunol. 32, 967-971 (2002).
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 967-971
-
-
Mulroy, T.1
McMahon, J.A.2
Burakoff, S.J.3
McMahon, A.P.4
Sen, J.5
-
46
-
-
0035842902
-
Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice
-
Hsu, W., Shakya, R. & Costantini, F. Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice. J. Cell Biol. 155, 1055-1064 (2001).
-
(2001)
J. Cell Biol.
, vol.155
, pp. 1055-1064
-
-
Hsu, W.1
Shakya, R.2
Costantini, F.3
-
47
-
-
15244345063
-
Frizzled 9 knockout mice have abnormal B cell development
-
30 Nov (doi:10.1182/blood-2004-06-2334)
-
Ranheim, E. A. et al. Frizzled 9 knockout mice have abnormal B cell development. Blood 30 Nov 2004 (doi:10.1182/blood-2004-06-2334).
-
(2004)
Blood
-
-
Ranheim, E.A.1
-
48
-
-
0346121607
-
Deletion of β-catenin impairs T cell development
-
Xu, Y., Banerjee, D., Huelsken, J., Birchmeier, W. & Sen, J. M. Deletion of β-catenin impairs T cell development. Nature Immunol. 4, 1177-1182 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 1177-1182
-
-
Xu, Y.1
Banerjee, D.2
Huelsken, J.3
Birchmeier, W.4
Sen, J.M.5
-
49
-
-
1642499734
-
β-catenin is dispensable for hematopoiesis and lymphopoiesis
-
Cobas, M. et al. β-catenin is dispensable for hematopoiesis and lymphopoiesis. J. Exp. Med. 199, 221-229 (2004). References 48 and 49 describe the phenotype of mice that are deficient in β-catenin; however, they report opposite results.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 221-229
-
-
Cobas, M.1
-
50
-
-
0033026520
-
Tcf-1-mediated transcription in T lymphocytes: Differential role for glycogen synthase kinase-3 in fibroblasts and T cells
-
Steal, F. J., Burgering, B. M., van de Wetering, M. & Clevers, H. C. Tcf-1-mediated transcription in T lymphocytes: differential role for glycogen synthase kinase-3 in fibroblasts and T cells. Int. Immunol. 11, 317-323 (1999).
-
(1999)
Int. Immunol.
, vol.11
, pp. 317-323
-
-
Steal, F.J.1
Burgering, B.M.2
Van De Wetering, M.3
Clevers, H.C.4
-
51
-
-
0035554684
-
Somatic activation of β-cateriin bypasses pre-TCR signaling and TCR selection in thymocyte development
-
Gounari, F. et al. Somatic activation of β-cateriin bypasses pre-TCR signaling and TCR selection in thymocyte development. Nature Immunol. 2, 863-869 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 863-869
-
-
Gounari, F.1
-
52
-
-
0347407819
-
β-catenin expression enhances generation of mature thymocytes
-
Mulroy T., Xu, Y. & Sen, J. M. β-Catenin expression enhances generation of mature thymocytes. Int. Immunol. 15, 1485-1494 (2003).
-
(2003)
Int. Immunol.
, vol.15
, pp. 1485-1494
-
-
Mulroy, T.1
Xu, Y.2
Sen, J.M.3
-
53
-
-
0028294603
-
Crosstalk in the mouse thymus
-
van Ewijk, W., Shores, E. W. & Singer, A. Crosstalk in the mouse thymus. Immunol. Today 15, 214-217 (1994).
-
(1994)
Immunol. Today
, vol.15
, pp. 214-217
-
-
Van Ewijk, W.1
Shores, E.W.2
Singer, A.3
-
54
-
-
0036852151
-
Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice
-
Baiciunaite, G. et al. Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice. Nature Immunol. 3, 1102-1108 (2002).
-
(2002)
Nature Immunol.
, vol.3
, pp. 1102-1108
-
-
Baiciunaite, G.1
-
55
-
-
0142254155
-
A transcriptional response to Wnt protein in human embryonic carcinoma cells
-
Willert, J., Epping, M., Pollack, J. R., Brown, P. O. & Nusse, R. A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev. Biol. [online] 2, 8 (2002).
-
(2002)
BMC Dev. Biol. [Online]
, vol.2
, pp. 8
-
-
Willert, J.1
Epping, M.2
Pollack, J.R.3
Brown, P.O.4
Nusse, R.5
-
56
-
-
18644373146
-
The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering, M. et al. The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 111, 241-250 (2002).
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
Van De Wetering, M.1
-
57
-
-
1642536445
-
+ thymocytes regulate proliferation and cell adhesion
-
+ thymocytes regulate proliferation and cell adhesion. J. Immunol. 172, 1099-1108 (2004). This report identifies target genes of the WNT-TCF1 signalling pathway in DN thymocytes. It is the first study that has used DNA microarrays to examine the target genes of a transcription factor that is required for lymphoid development
-
(2004)
J. Immunol.
, vol.172
, pp. 1099-1108
-
-
Staal, F.J.1
-
58
-
-
0030896455
-
ALY a context-dependent coactivator of LEF-1 and AML-1, is required for TCRα enhancer function
-
Bruhn, L., Munnerlyn, A, & Grosschedl, R. ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRα enhancer function. Genes Dev. 11, 640-653 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 640-653
-
-
Bruhn, L.1
Munnerlyn, A.2
Grosschedl, R.3
-
59
-
-
0033711624
-
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism
-
Reya, T. et al. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity 13, 15-24 (2000). This paper describes the defect in B-cell development of LEF1-deficient mice. In addition, it shows the importance of WNT signalling for the proliferation of pro-B cells.
-
(2000)
Immunity
, vol.13
, pp. 15-24
-
-
Reya, T.1
-
60
-
-
0037100392
-
The B cell antigen receptor regulates the transcriptional activator β-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3
-
Christian, S. L., Sims, P. V. & Gold, M. R. The B cell antigen receptor regulates the transcriptional activator β-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3. J. Immunol. 169, 758-769 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 758-769
-
-
Christian, S.L.1
Sims, P.V.2
Gold, M.R.3
-
61
-
-
12144287598
-
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells
-
Muller-Tidow, C. et al. Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells. Mol. Cell. Biol. 24, 2890-2904 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2890-2904
-
-
Muller-Tidow, C.1
-
62
-
-
1542267803
-
Activation of the Wnt signaling pathway in chronic lymphocytic leukemia
-
Lu, D. et al. Activation of the Wnt signaling pathway in chronic lymphocytic leukemia. Proc. Natl Acad. Sci. USA 101, 3113-3123 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3113-3123
-
-
Lu, D.1
-
63
-
-
0033613097
-
Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WMT gene in pre-B acute lymphoblastoid leukemia
-
McWhirter, J. R. et al. Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WMT gene in pre-B acute lymphoblastoid leukemia. Proc. Natl Acad. Sci. USA 96, 11464-11469 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 11464-11469
-
-
McWhirter, J.R.1
-
64
-
-
3943088431
-
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
-
Jamieson, C. H. et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N. Engl. J. Med. 351, 657-667 (2004). This is the first description ol the involvement ol dysregulated WNT signalling in a haematological malignancy of humans.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 657-667
-
-
Jamieson, C.H.1
-
65
-
-
0346363760
-
The role of the Wnt-signaling antagonist DKK 1 in the development of osteolytic lesions in multiple myeloma
-
Tian, E. et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N. Engl. J. Med. 349, 2483-2494 (2003).
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2483-2494
-
-
Tian, E.1
-
66
-
-
11144355390
-
Illegitimate WMT signaling promotes proliferation of multiple myeloma cells
-
Derksen, P. W. et al. Illegitimate WMT signaling promotes proliferation of multiple myeloma cells. Proc. Natl Acad. Sci. USA 101, 6122-6127 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6122-6127
-
-
Derksen, P.W.1
-
67
-
-
0345356929
-
Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue
-
Ljang, H. et al. Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue. Cancer Cell 4, 349-360 (2003).
-
(2003)
Cancer Cell
, vol.4
, pp. 349-360
-
-
Ljang, H.1
-
68
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
Nicolas, M. et al. Notch1 functions as a tumor suppressor in mouse skin. Nature Genet. 33, 416-421 (2003).
-
(2003)
Nature Genet.
, vol.33
, pp. 416-421
-
-
Nicolas, M.1
-
69
-
-
8644219672
-
LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis
-
Galceran, J., Sustmann, C., Hsu, S. C., Folberth, S. & Grosschedl, R. LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis. Genes Dev. 18, 2713-2723 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 2713-2723
-
-
Galceran, J.1
Sustmann, C.2
Hsu, S.C.3
Folberth, S.4
Grosschedl, R.5
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