메뉴 건너뛰기




Volumn 33, Issue 7, 2005, Pages 738-746

Hypothesis: Cell plasticity, linking embryonal stem cells to adult stem cell reservoirs and metastatic cancer cells?

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; EPIDERMAL GROWTH FACTOR; MACROPHAGE ACTIVATING FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PLATELET DERIVED GROWTH FACTOR; SCATTER FACTOR; SMAD2 PROTEIN; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; ZINC TRANSPORTER;

EID: 20444469539     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2005.03.002     Document Type: Article
Times cited : (43)

References (148)
  • 1
    • 0029553183 scopus 로고
    • An overview of epithelio-mesenchymal transformation
    • E.D. Hay An overview of epithelio-mesenchymal transformation Acta Anat 154 1995 8 20
    • (1995) Acta Anat , vol.154 , pp. 8-20
    • Hay, E.D.1
  • 2
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • J.A. Thomson, J. Itskovitz-Eldor, and S.S. Shapiro Embryonic stem cell lines derived from human blastocysts Science 282 1998 1145 1147
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 3
    • 1842527031 scopus 로고    scopus 로고
    • Environmental guidance of normal and tumor cell plasticity: Epithelial mesenchymal transitions as a paradigm
    • G. Prindull, and D. Zipori Environmental guidance of normal and tumor cell plasticity: epithelial mesenchymal transitions as a paradigm Blood 103 2004 2892 2899
    • (2004) Blood , vol.103 , pp. 2892-2899
    • Prindull, G.1    Zipori, D.2
  • 4
    • 0025952778 scopus 로고
    • Cell cycle dependence of laminar determination in developing neocortex
    • S. McConnell, and C. Kaznowski Cell cycle dependence of laminar determination in developing neocortex Science 254 1991 282 285
    • (1991) Science , vol.254 , pp. 282-285
    • McConnell, S.1    Kaznowski, C.2
  • 5
    • 0036709213 scopus 로고    scopus 로고
    • Signalling, cell cycle and pluripotency in embryonic stem cells
    • T. Burdon, A. Smith, and P. Savatier Signalling, cell cycle and pluripotency in embryonic stem cells Trends Cell Biol 12 2002 432 438
    • (2002) Trends Cell Biol , vol.12 , pp. 432-438
    • Burdon, T.1    Smith, A.2    Savatier, P.3
  • 7
    • 0035967892 scopus 로고    scopus 로고
    • The evolving concept of a stem cell: Entity or function?
    • H.M. Blau, T.R. Brazelton, and J.M. Weimann The evolving concept of a stem cell: entity or function? Cell 105 2001 829 841
    • (2001) Cell , vol.105 , pp. 829-841
    • Blau, H.M.1    Brazelton, T.R.2    Weimann, J.M.3
  • 8
    • 0036830524 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: A mesodermal cell strategy for evolutive innovation in metazoans
    • J.M. Perez-Pomares, and R. Munoz-Chapuli Epithelial-mesenchymal transitions: a mesodermal cell strategy for evolutive innovation in metazoans Anat Rec 268 2002 343 351
    • (2002) Anat Rec , vol.268 , pp. 343-351
    • Perez-Pomares, J.M.1    Munoz-Chapuli, R.2
  • 9
    • 0037114699 scopus 로고    scopus 로고
    • The chiaroscuro stem cell: A unified stem cell theory
    • P.J. Quesenberry, G.A. Colvin, and J.F. Lambert The chiaroscuro stem cell: a unified stem cell theory Blood 100 2002 4266 4271
    • (2002) Blood , vol.100 , pp. 4266-4271
    • Quesenberry, P.J.1    Colvin, G.A.2    Lambert, J.F.3
  • 10
    • 0348231980 scopus 로고    scopus 로고
    • Perspective: Stem cells react! Cell lineages as complex adaptive systems
    • N.D. Theise Perspective: stem cells react! Cell lineages as complex adaptive systems Exp Hematol 32 2004 25 27
    • (2004) Exp Hematol , vol.32 , pp. 25-27
    • Theise, N.D.1
  • 13
    • 0037183884 scopus 로고    scopus 로고
    • Little evidence for developmental plasticity of adult hematopoietic stem cells
    • A.J. Wagers, R.I. Sherwood, J.L. Christensen, and I.L. Weissman Little evidence for developmental plasticity of adult hematopoietic stem cells Science 297 2002 2256 2259
    • (2002) Science , vol.297 , pp. 2256-2259
    • Wagers, A.J.1    Sherwood, R.I.2    Christensen, J.L.3    Weissman, I.L.4
  • 15
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • K. Mitsui, Y. Tokuzawa, and H. Itoh The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and ES cells Cell 113 2003 631 642
    • (2003) Cell , vol.113 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3
  • 17
    • 0034070944 scopus 로고    scopus 로고
    • DNA microarray analyses of genes regulated during the differentiation of embryonic stem cells
    • D.L. Kelly, and A. Rizzino DNA microarray analyses of genes regulated during the differentiation of embryonic stem cells Mol Reprod Dev 56 2000 113 123
    • (2000) Mol Reprod Dev , vol.56 , pp. 113-123
    • Kelly, D.L.1    Rizzino, A.2
  • 18
    • 11144355188 scopus 로고    scopus 로고
    • Gene expression in human embryonic stem cell lines: Unique molecular signature
    • B. Bhattacharya, T. Miura, and R. Brandenberger Gene expression in human embryonic stem cell lines: unique molecular signature Blood 103 2004 2956 2964
    • (2004) Blood , vol.103 , pp. 2956-2964
    • Bhattacharya, B.1    Miura, T.2    Brandenberger, R.3
  • 19
    • 11144357877 scopus 로고    scopus 로고
    • Differences between human and mouse embryonic stem cells
    • I. Ginis, Y. Luo, and T. Miura Differences between human and mouse embryonic stem cells Dev Biol 269 2004 360 380
    • (2004) Dev Biol , vol.269 , pp. 360-380
    • Ginis, I.1    Luo, Y.2    Miura, T.3
  • 20
  • 21
    • 0027321548 scopus 로고
    • Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
    • A. Nagy, J. Rossant, R. Nagy, W. Abramow-Newerly, and J.C. Roder Derivation of completely cell culture-derived mice from early-passage embryonic stem cells Proc Natl Acad Sci U S A 90 1993 8424 8428
    • (1993) Proc Natl Acad Sci U S a , vol.90 , pp. 8424-8428
    • Nagy, A.1    Rossant, J.2    Nagy, R.3    Abramow-Newerly, W.4    Roder, J.C.5
  • 22
    • 18344408969 scopus 로고    scopus 로고
    • Derivation of oocytes from mouse embryonic stem cells
    • K. Hübner, G. Fuhrmann, and L.K. Christenson Derivation of oocytes from mouse embryonic stem cells Science 300 2003 1251 1256
    • (2003) Science , vol.300 , pp. 1251-1256
    • Hübner, K.1    Fuhrmann, G.2    Christenson, L.K.3
  • 23
    • 0024433706 scopus 로고
    • A family of octamer-specific proteins present during mouse embryogenesis: Evidence for germline-specific expression of an Oct factor
    • H.R. Schöler, A.K. Hatzopoulos, R. Balling, N. Suzuki, and P. Gruss A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor EMBO J 8 1989 2543 2550
    • (1989) EMBO J , vol.8 , pp. 2543-2550
    • Schöler, H.R.1    Hatzopoulos, A.K.2    Balling, R.3    Suzuki, N.4    Gruss, P.5
  • 24
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
    • J. Nichols, B. Zevnik, and K. Anastassiadis Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4 Cell 95 1998 379 391
    • (1998) Cell , vol.95 , pp. 379-391
    • Nichols, J.1    Zevnik, B.2    Anastassiadis, K.3
  • 25
    • 0032940189 scopus 로고    scopus 로고
    • Synergism with germ line transcription factor Oct-4: Viral oncoproteins share the ability to mimic a stem cell-specific activity
    • A. Brehm, K. Ohbo, W. Zwerschke, V. Botquin, P. Jansen-Dürr, and H.R. Schöler Synergism with germ line transcription factor Oct-4: viral oncoproteins share the ability to mimic a stem cell-specific activity Mol Cell Biol 19 1999 2635 2643
    • (1999) Mol Cell Biol , vol.19 , pp. 2635-2643
    • Brehm, A.1    Ohbo, K.2    Zwerschke, W.3    Botquin, V.4    Jansen-Dürr, P.5    Schöler, H.R.6
  • 26
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of nanog, a pluripotency sustaining factor in embryonic stem cells
    • I. Chambers, D. Colby, and M. Robertson Functional expression cloning of nanog, a pluripotency sustaining factor in embryonic stem cells Cell 113 2003 643 655
    • (2003) Cell , vol.113 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3
  • 27
    • 0347597774 scopus 로고    scopus 로고
    • Ephrin receptor, EphB4, regulates ES cell differentiation of primitive mammalian hemangioblasts, blood, cardiomyocytes, and blood vessels
    • Z. Wang, K. Cohen, Y. Shao, P. Mole, D. Dombkowski, and D.T. Scadden Ephrin receptor, EphB4, regulates ES cell differentiation of primitive mammalian hemangioblasts, blood, cardiomyocytes, and blood vessels Blood 103 2004 100 109
    • (2004) Blood , vol.103 , pp. 100-109
    • Wang, Z.1    Cohen, K.2    Shao, Y.3    Mole, P.4    Dombkowski, D.5    Scadden, D.T.6
  • 28
    • 0345687164 scopus 로고    scopus 로고
    • Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors
    • J.M. Sperger, X. Chen, and J.S. Draper Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors Proc Natl Acad Sci 100 2003 13350 13355
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 13350-13355
    • Sperger, J.M.1    Chen, X.2    Draper, J.S.3
  • 29
    • 0041560908 scopus 로고    scopus 로고
    • Molecular signature of human embryonic stem cells and its comparison with the mouse
    • N. Sato, I.M. Sanjuan, M. Heke, M. Uchida, F. Naef, and A.H. Brivanlou Molecular signature of human embryonic stem cells and its comparison with the mouse Dev Biol 260 2003 404 413
    • (2003) Dev Biol , vol.260 , pp. 404-413
    • Sato, N.1    Sanjuan, I.M.2    Heke, M.3    Uchida, M.4    Naef, F.5    Brivanlou, A.H.6
  • 30
    • 0346250854 scopus 로고    scopus 로고
    • The transcriptome profile of human embryonic stem cells as defined by SAGE
    • M. Richards, S.P. Tan, J.H. Tan, W.K. Chan, and A. Bongso The transcriptome profile of human embryonic stem cells as defined by SAGE Stem Cells 22 2004 51 64
    • (2004) Stem Cells , vol.22 , pp. 51-64
    • Richards, M.1    Tan, S.P.2    Tan, J.H.3    Chan, W.K.4    Bongso, A.5
  • 31
    • 0345528866 scopus 로고    scopus 로고
    • Embryonic origins of mammalian hematopoiesis
    • M.H. Baron Embryonic origins of mammalian hematopoiesis Exp Hematol 31 2003 1160 1169
    • (2003) Exp Hematol , vol.31 , pp. 1160-1169
    • Baron, M.H.1
  • 32
    • 2542418035 scopus 로고    scopus 로고
    • - hematopoietic precursors derived from human embryonic stem cells exhibit an embryonic gene expression pattern
    • - hematopoietic precursors derived from human embryonic stem cells exhibit an embryonic gene expression pattern Blood 103 2004 4134 4141
    • (2004) Blood , vol.103 , pp. 4134-4141
    • Lu, S.J.1    Li, F.2    Vida, L.3    Honig, G.R.4
  • 35
    • 0035214579 scopus 로고    scopus 로고
    • Step-wise divergence of primitive and definitive haematopoietic and endothelial cell lineages during embryonic stem cell differentiation
    • T. Fujimoto, M. Ogawa, and N. Minegishi Step-wise divergence of primitive and definitive haematopoietic and endothelial cell lineages during embryonic stem cell differentiation Genes Cells 6 2001 1113 1127
    • (2001) Genes Cells , vol.6 , pp. 1113-1127
    • Fujimoto, T.1    Ogawa, M.2    Minegishi, N.3
  • 36
    • 0036340212 scopus 로고    scopus 로고
    • Insufficient VEGF activity in yolk sac endoderm compromises hematopoietic and endothelial differentiation
    • A. Damert, L. Miquerol, M. Gertsenstein, W. Risau, and A. Nagy Insufficient VEGF activity in yolk sac endoderm compromises hematopoietic and endothelial differentiation Development 129 2002 1881 1892
    • (2002) Development , vol.129 , pp. 1881-1892
    • Damert, A.1    Miquerol, L.2    Gertsenstein, M.3    Risau, W.4    Nagy, A.5
  • 38
    • 0842328847 scopus 로고    scopus 로고
    • Functional endothelial cells derived from rhesus monkey embryonic stem cells
    • D.S. Kaufman, R.L. Lewis, E.T. Hanson, R. Auerbach, J. Plendl, and J.A. Thomson Functional endothelial cells derived from rhesus monkey embryonic stem cells Blood 103 2004 1325 1332
    • (2004) Blood , vol.103 , pp. 1325-1332
    • Kaufman, D.S.1    Lewis, R.L.2    Hanson, E.T.3    Auerbach, R.4    Plendl, J.5    Thomson, J.A.6
  • 39
    • 0036285647 scopus 로고    scopus 로고
    • Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta
    • M.F.T.R. de Bruijn, X. Ma, C. Robin, K. Ottersbach, M.J. Sanchez, and H. Dzierzak Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta Immunity 16 2002 673 683
    • (2002) Immunity , vol.16 , pp. 673-683
    • De Bruijn, M.F.T.R.1    Ma, X.2    Robin, C.3    Ottersbach, K.4    Sanchez, M.J.5    Dzierzak, H.6
  • 40
    • 0036714991 scopus 로고    scopus 로고
    • Blood forming potential of vascular endothelium in the human embryo
    • E. Oberlin, M. Tavian, I. Blazsek, and B. Péault Blood forming potential of vascular endothelium in the human embryo Development 129 2002 4147 4157
    • (2002) Development , vol.129 , pp. 4147-4157
    • Oberlin, E.1    Tavian, M.2    Blazsek, I.3    Péault, B.4
  • 41
    • 0037442989 scopus 로고    scopus 로고
    • Plastic adult stem cells: Will they graduate from the school of hard knocks?
    • M.R. Alison, R. Poulsom, and W.R. Otto Plastic adult stem cells: will they graduate from the school of hard knocks? J Cell Sci 116 2003 599 603
    • (2003) J Cell Sci , vol.116 , pp. 599-603
    • Alison, M.R.1    Poulsom, R.2    Otto, W.R.3
  • 42
    • 0036322544 scopus 로고    scopus 로고
    • Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain
    • Y. Jiang, B. Vaessen, T. Lenvik, M. Blackstad, M. Reyes, and C.M. Verfaillie Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain Exp Hematol 30 2002 896 904
    • (2002) Exp Hematol , vol.30 , pp. 896-904
    • Jiang, Y.1    Vaessen, B.2    Lenvik, T.3    Blackstad, M.4    Reyes, M.5    Verfaillie, C.M.6
  • 43
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Y. Jiang, B.N. Jahagirdar, and R.L. Reinhardt Pluripotency of mesenchymal stem cells derived from adult marrow Nature 418 2002 41 49
    • (2002) Nature , vol.418 , pp. 41-49
    • Jiang, Y.1    Jahagirdar, B.N.2    Reinhardt, R.L.3
  • 44
    • 1442356953 scopus 로고    scopus 로고
    • Isolation of multipotent mesenchymal stem cells from umbilical cord blood
    • O.K. Lee, T.K. Kuo, W.M. Chen, K.D. Lee, S.L. Hsieh, and T.H. Chen Isolation of multipotent mesenchymal stem cells from umbilical cord blood Blood 103 2004 1669 1675
    • (2004) Blood , vol.103 , pp. 1669-1675
    • Lee, O.K.1    Kuo, T.K.2    Chen, W.M.3    Lee, K.D.4    Hsieh, S.L.5    Chen, T.H.6
  • 45
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • M.F. Pittenger, A.M. Mackay, and S.C. Beck Multilineage potential of adult human mesenchymal stem cells Science 284 1999 143 147
    • (1999) Science , vol.284 , pp. 143-147
    • Pittenger, M.F.1    MacKay, A.M.2    Beck, S.C.3
  • 46
    • 0034056758 scopus 로고    scopus 로고
    • Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model
    • A. Muraglia, R. Cancedda, and R. Quarto Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model J Cell Sci 113 2000 1161 1166
    • (2000) J Cell Sci , vol.113 , pp. 1161-1166
    • Muraglia, A.1    Cancedda, R.2    Quarto, R.3
  • 47
    • 0034531907 scopus 로고    scopus 로고
    • From marrow to brain: Expression of neuronal phenotypes in adult mice
    • T.R. Brazelton, F.M.V. Rossi, G.I. Keshet, and H.M. Blau From marrow to brain: expression of neuronal phenotypes in adult mice Science 290 2000 1775 1779
    • (2000) Science , vol.290 , pp. 1775-1779
    • Brazelton, T.R.1    Rossi, F.M.V.2    Keshet, G.I.3    Blau, H.M.4
  • 48
    • 0034532106 scopus 로고    scopus 로고
    • Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow
    • E. Mezey, K.J. Chandross, G. Harta, R.A. Maki, and S.R. McKercher Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow Science 290 2000 1779 1782
    • (2000) Science , vol.290 , pp. 1779-1782
    • Mezey, E.1    Chandross, K.J.2    Harta, G.3    Maki, R.A.4    McKercher, S.R.5
  • 49
    • 0041467303 scopus 로고    scopus 로고
    • Cardiomyocyte regeneration from circulating bone marrow cells in mice
    • Y. Kuramochi, R. Fukazawa, and M. Migita Cardiomyocyte regeneration from circulating bone marrow cells in mice Pediatr Res 54 2003 319 325
    • (2003) Pediatr Res , vol.54 , pp. 319-325
    • Kuramochi, Y.1    Fukazawa, R.2    Migita, M.3
  • 50
    • 2442464824 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Paradoxes of passaging
    • E.H. Javazon, K.J. Beggs, and A.W. Flake Mesenchymal stem cells: paradoxes of passaging Exp Hematol 32 2004 414 425
    • (2004) Exp Hematol , vol.32 , pp. 414-425
    • Javazon, E.H.1    Beggs, K.J.2    Flake, A.W.3
  • 51
    • 0034848122 scopus 로고    scopus 로고
    • Isolation of multipotent adult stem cells from the dermis of mammalian skin
    • J.G. Toma, M. Akhavan, and K.J. Fernandes Isolation of multipotent adult stem cells from the dermis of mammalian skin Nat Cell Biol 3 2001 778 784
    • (2001) Nat Cell Biol , vol.3 , pp. 778-784
    • Toma, J.G.1    Akhavan, M.2    Fernandes, K.J.3
  • 53
    • 7944237574 scopus 로고    scopus 로고
    • A dermal niche for multi-potent adult skin-derived precursror cells
    • K.J.L. Fernandes, I.A. McKenzie, and P. Mill A dermal niche for multi-potent adult skin-derived precursror cells Nat Cell Biol 6 2004 1082 1093
    • (2004) Nat Cell Biol , vol.6 , pp. 1082-1093
    • Fernandes, K.J.L.1    McKenzie, I.A.2    Mill, P.3
  • 54
    • 7444257984 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Harnessing cell plasticity to tissue and organ repair
    • D. Zipori Mesenchymal stem cells: harnessing cell plasticity to tissue and organ repair Blood Cells Mol Dis 33 2004 211 215
    • (2004) Blood Cells Mol Dis , vol.33 , pp. 211-215
    • Zipori, D.1
  • 55
    • 0036225224 scopus 로고    scopus 로고
    • Hematopoiesis and stem cells: Plasticity versus developmental heterogeneity
    • S.H. Orkin, and L.I. Zon Hematopoiesis and stem cells: plasticity versus developmental heterogeneity Nat Immunol 3 2002 323 328
    • (2002) Nat Immunol , vol.3 , pp. 323-328
    • Orkin, S.H.1    Zon, L.I.2
  • 56
    • 0037019331 scopus 로고    scopus 로고
    • Stem-cell competition
    • S.H. Orkin, and S.J. Morrison Stem-cell competition Nature 418 2002 25 27
    • (2002) Nature , vol.418 , pp. 25-27
    • Orkin, S.H.1    Morrison, S.J.2
  • 57
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its applications for fibrosis
    • R. Kalluri, and E.G. Neilson Epithelial-mesenchymal transition and its applications for fibrosis J Clin Invest 112 2003 1776 1784
    • (2003) J Clin Invest , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 58
    • 0842287502 scopus 로고    scopus 로고
    • Stem cell fusion confusion
    • K. O'Malley, and E.W. Scott Stem cell fusion confusion Exp Hematol 32 2004 131 134
    • (2004) Exp Hematol , vol.32 , pp. 131-134
    • O'Malley, K.1    Scott, E.W.2
  • 60
    • 0034695926 scopus 로고    scopus 로고
    • Spatial separation of parental genomes in preimplantation mouse embryos
    • W. Mayer, A. Smith, R. Fundele, and T. Haaf Spatial separation of parental genomes in preimplantation mouse embryos J Cell Biol 148 2000 629 634
    • (2000) J Cell Biol , vol.148 , pp. 629-634
    • Mayer, W.1    Smith, A.2    Fundele, R.3    Haaf, T.4
  • 61
    • 1842579570 scopus 로고    scopus 로고
    • Dynamic reorganization of chromatin structure and selective DNA demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro
    • H. Tagoh, S. Melnik, P. Lefevre, S. Chong, A.D. Riggs, and C. Bonifer Dynamic reorganization of chromatin structure and selective DNA demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro Blood 103 2004 2950 2955
    • (2004) Blood , vol.103 , pp. 2950-2955
    • Tagoh, H.1    Melnik, S.2    Lefevre, P.3    Chong, S.4    Riggs, A.D.5    Bonifer, C.6
  • 63
    • 0036191343 scopus 로고    scopus 로고
    • Expression of cell adhesion molecules during human preimplantation embryo development
    • D.J. Bloor, A.D. Metcalf, A. Rutherford, D.R. Brison, and S.J. Kimber Expression of cell adhesion molecules during human preimplantation embryo development Mol Hum Reprod 8 2002 237 245
    • (2002) Mol Hum Reprod , vol.8 , pp. 237-245
    • Bloor, D.J.1    Metcalf, A.D.2    Rutherford, A.3    Brison, D.R.4    Kimber, S.J.5
  • 64
    • 0035344463 scopus 로고    scopus 로고
    • Intercellular communication in preimplantation development: The role of gap junctions
    • G.M. Kidder, and E. Winterhagen Intercellular communication in preimplantation development: the role of gap junctions Front Biosci 6 2001 D731 D736
    • (2001) Front Biosci , vol.6
    • Kidder, G.M.1    Winterhagen, E.2
  • 65
    • 0036242189 scopus 로고    scopus 로고
    • Functional significance of gap junctional coupling in preimplantation development
    • F.D. Houghton, K.J. Barr, and G. Walter Functional significance of gap junctional coupling in preimplantation development Biol Reprod 66 2002 1403 1412
    • (2002) Biol Reprod , vol.66 , pp. 1403-1412
    • Houghton, F.D.1    Barr, K.J.2    Walter, G.3
  • 66
    • 0035876123 scopus 로고    scopus 로고
    • Inner cell mass-specific expression of a cell adhesion molecule (PECAM-1/CD31) in the mouse blastocyst
    • P. Robson, P. Stein, B. Zhou, R.M. Schultz, and H.S. Baldwin Inner cell mass-specific expression of a cell adhesion molecule (PECAM-1/CD31) in the mouse blastocyst Dev Biol 234 2001 317 329
    • (2001) Dev Biol , vol.234 , pp. 317-329
    • Robson, P.1    Stein, P.2    Zhou, B.3    Schultz, R.M.4    Baldwin, H.S.5
  • 67
    • 0035805055 scopus 로고    scopus 로고
    • Multi-organ, multilineage engraftment by a single bone marrow-derived stem cell
    • D.S. Krause, N.D. Theise, and M.I. Collector Multi-organ, multilineage engraftment by a single bone marrow-derived stem cell Cell 105 2001 369 377
    • (2001) Cell , vol.105 , pp. 369-377
    • Krause, D.S.1    Theise, N.D.2    Collector, M.I.3
  • 68
    • 0036566226 scopus 로고    scopus 로고
    • Differentiation plasticity of hematopoietic cells
    • T. Graf Differentiation plasticity of hematopoietic cells Blood 99 2002 3089 3101
    • (2002) Blood , vol.99 , pp. 3089-3101
    • Graf, T.1
  • 69
    • 0020358296 scopus 로고
    • Epithelia suspended in collagen gels lose polarity and express characteristics of migrating mesenchymal cells
    • G. Greenburg, and E.D. Hay Epithelia suspended in collagen gels lose polarity and express characteristics of migrating mesenchymal cells J Cell Biol 95 1982 333 339
    • (1982) J Cell Biol , vol.95 , pp. 333-339
    • Greenburg, G.1    Hay, E.D.2
  • 70
    • 0031756278 scopus 로고    scopus 로고
    • Relevance of extra-cellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis
    • Renal Physiol. 44
    • E.I. Wallner, Q. Yang, D.R. Peterson, J. Wada, and Y.S. Kanwar Relevance of extra-cellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis Am J Physiol 275 Renal Physiol. 44 1998 F467 F477
    • (1998) Am J Physiol , vol.275
    • Wallner, E.I.1    Yang, Q.2    Peterson, D.R.3    Wada, J.4    Kanwar, Y.S.5
  • 71
  • 72
    • 9144246932 scopus 로고    scopus 로고
    • Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
    • L.A. Timmerman, J. Grego-Bessa, and A. Raya Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation Genes Dev 18 2004 99 115
    • (2004) Genes Dev , vol.18 , pp. 99-115
    • Timmerman, L.A.1    Grego-Bessa, J.2    Raya, A.3
  • 73
    • 1642619124 scopus 로고    scopus 로고
    • Lung stem cells: New paradigms
    • D.N. Kotton, R. Summer, and A. Fine Lung stem cells: new paradigms Exp Hematol 32 2004 340 343
    • (2004) Exp Hematol , vol.32 , pp. 340-343
    • Kotton, D.N.1    Summer, R.2    Fine, A.3
  • 74
    • 0030670132 scopus 로고    scopus 로고
    • The early role of FSP1 in epithelial-mesenchymal transformation
    • H. Okada, T.M. Danoff, R. Kalluri, and E.G. Neilson The early role of FSP1 in epithelial-mesenchymal transformation Am J Physiol 273 1997 563 574
    • (1997) Am J Physiol , vol.273 , pp. 563-574
    • Okada, H.1    Danoff, T.M.2    Kalluri, R.3    Neilson, E.G.4
  • 75
  • 76
    • 1542289674 scopus 로고    scopus 로고
    • Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury
    • S. Saika, S. Kono-Saika, and Y. Ohnishi Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury Am J Pathol 164 2004 651 663
    • (2004) Am J Pathol , vol.164 , pp. 651-663
    • Saika, S.1    Kono-Saika, S.2    Ohnishi, Y.3
  • 77
    • 0034973221 scopus 로고    scopus 로고
    • Role of activin a in negative regulation of normal and tumor B lymphocytes
    • D. Zipori, and M. Barda-Saad Role of activin A in negative regulation of normal and tumor B lymphocytes J Leuk Biol 69 2001 867 873
    • (2001) J Leuk Biol , vol.69 , pp. 867-873
    • Zipori, D.1    Barda-Saad, M.2
  • 78
    • 85047697401 scopus 로고    scopus 로고
    • The mesenchyme expresses T cell receptor mRNA: Relevance to cell growth control
    • M. Barda-Saad, Y. Shav-Tal, and A.L. Rozenszajn The mesenchyme expresses T cell receptor mRNA: relevance to cell growth control Oncogene 21 2002 2029 2036
    • (2002) Oncogene , vol.21 , pp. 2029-2036
    • Barda-Saad, M.1    Shav-Tal, Y.2    Rozenszajn, A.L.3
  • 79
    • 0036281597 scopus 로고    scopus 로고
    • Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization
    • M.B. Grant, W.S. May, and S. Caballero Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization Nat Med 8 2002 607 612
    • (2002) Nat Med , vol.8 , pp. 607-612
    • Grant, M.B.1    May, W.S.2    Caballero, S.3
  • 82
    • 2942585152 scopus 로고    scopus 로고
    • A phase space model of hematopoiesis and the concept of stem cell renewal
    • M.A. Kirkland A phase space model of hematopoiesis and the concept of stem cell renewal Exp Hematol 32 2004 511 519
    • (2004) Exp Hematol , vol.32 , pp. 511-519
    • Kirkland, M.A.1
  • 83
  • 85
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • J. Yang, and Y. Liu Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis Am J Pathol 159 2001 1465 1475
    • (2001) Am J Pathol , vol.159 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 86
    • 1642379154 scopus 로고    scopus 로고
    • The role of epithelial-to-mesenchymal transition in renal fibrosis
    • M. Zeisberg, and R. Kalluri The role of epithelial-to-mesenchymal transition in renal fibrosis J Mol Med 82 2004 175 181
    • (2004) J Mol Med , vol.82 , pp. 175-181
    • Zeisberg, M.1    Kalluri, R.2
  • 87
    • 0346055104 scopus 로고    scopus 로고
    • Menstrual effluent induces epithelial-mesenchymal transitions in mesothelial cells
    • A.Y. Demir, P.G. Groothuis, and A.W. Nap Menstrual effluent induces epithelial-mesenchymal transitions in mesothelial cells Hum Reprod 19 2004 21 29
    • (2004) Hum Reprod , vol.19 , pp. 21-29
    • Demir, A.Y.1    Groothuis, P.G.2    Nap, A.W.3
  • 88
    • 0037472881 scopus 로고    scopus 로고
    • Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells
    • M. Yánez-Mo, E. Lara-Pezzi, and R. Selgas Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells N Engl J Med 348 2003 403 413
    • (2003) N Engl J Med , vol.348 , pp. 403-413
    • Yánez-Mo, M.1    Lara-Pezzi, E.2    Selgas, R.3
  • 89
    • 0035147248 scopus 로고    scopus 로고
    • Co-expression of tenascin-C and vimentin in human breast cancer cells indicates phenotypic transdifferentiation during tumor progression: Correlation with histopathological parameters, hormone receptors, and oncoproteins
    • N. Dandachi, C. Hauser-Kronberger, and E. More Co-expression of tenascin-C and vimentin in human breast cancer cells indicates phenotypic transdifferentiation during tumor progression: correlation with histopathological parameters, hormone receptors, and oncoproteins J Pathol 193 2001 181 189
    • (2001) J Pathol , vol.193 , pp. 181-189
    • Dandachi, N.1    Hauser-Kronberger, C.2    More, E.3
  • 90
    • 0036304111 scopus 로고    scopus 로고
    • Metastasis is driven by sequential elevation of H-ras and Smad2 levels
    • M. Oft, R.J. Akhurst, and A. Balmain Metastasis is driven by sequential elevation of H-ras and Smad2 levels Nat Cell Biol 4 2002 488 494
    • (2002) Nat Cell Biol , vol.4 , pp. 488-494
    • Oft, M.1    Akhurst, R.J.2    Balmain, A.3
  • 91
    • 0034787967 scopus 로고    scopus 로고
    • MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits
    • A.M. Tester, N. Ruangpanit, R.L. Anderson, and E.W. Thompson MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits Clin Exp Metastasis 18 2001 553 560
    • (2001) Clin Exp Metastasis , vol.18 , pp. 553-560
    • Tester, A.M.1    Ruangpanit, N.2    Anderson, R.L.3    Thompson, E.W.4
  • 92
    • 0037331707 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition in human breast cancer can provide a non-malignant stroma
    • O.W. Petersen, N.H. Lind, and T. Gudjonsson Epithelial-to-mesenchymal transition in human breast cancer can provide a non-malignant stroma Am J Pathol 162 2003 391 402
    • (2003) Am J Pathol , vol.162 , pp. 391-402
    • Petersen, O.W.1    Lind, N.H.2    Gudjonsson, T.3
  • 94
    • 0344845003 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and pathologies
    • J.P. Thiery Epithelial-mesenchymal transitions in development and pathologies Curr Opin Cell Biol 15 2003 740 746
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 740-746
    • Thiery, J.P.1
  • 95
    • 8444226084 scopus 로고    scopus 로고
    • Zinc transporter LIV-1: A link between cellular development and cancer progression
    • K.M. Taylor, S. Hiscox, and R.I. Nicholson Zinc transporter LIV-1: a link between cellular development and cancer progression Trends Endocrin Metabol 15 2004 461 463
    • (2004) Trends Endocrin Metabol , vol.15 , pp. 461-463
    • Taylor, K.M.1    Hiscox, S.2    Nicholson, R.I.3
  • 96
    • 2442674220 scopus 로고    scopus 로고
    • Zinc transporter LIV1 controls epithelial-mesenchymal transition in zebrafish gastrula organizer
    • S. Yamashita, C. Miyagi, T. Fukada, N. Kagara, Y.S. Che, and T. Hirano Zinc transporter LIV1 controls epithelial-mesenchymal transition in zebrafish gastrula organizer Nature 429 2004 298 302
    • (2004) Nature , vol.429 , pp. 298-302
    • Yamashita, S.1    Miyagi, C.2    Fukada, T.3    Kagara, N.4    Che, Y.S.5    Hirano, T.6
  • 97
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • A. Cano, M.A. Perez-Moreno, and I. Rodrigo The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression Nat Cell Biol 2 2000 76 83
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3
  • 99
    • 85047698213 scopus 로고    scopus 로고
    • Correlation of Snail expression with histologic grade and lymph node status in breast carcinomas
    • M.J. Blanco, G. Moreno-Bueno, and D. Sarrio Correlation of Snail expression with histologic grade and lymph node status in breast carcinomas Oncogene 21 2002 3241 3246
    • (2002) Oncogene , vol.21 , pp. 3241-3246
    • Blanco, M.J.1    Moreno-Bueno, G.2    Sarrio, D.3
  • 100
    • 0025037681 scopus 로고
    • Acidic fibroblast growth factor is a modulator of epithelial plasticity in a rat bladder carcinoma cell line
    • A.M. Valles, B. Boyer, J. Badet, G.C. Tucker, D. Barritault, and J.P. Thiery Acidic fibroblast growth factor is a modulator of epithelial plasticity in a rat bladder carcinoma cell line Proc Natl Acad Sci U S A 87 1990 1124 1128
    • (1990) Proc Natl Acad Sci U S a , vol.87 , pp. 1124-1128
    • Valles, A.M.1    Boyer, B.2    Badet, J.3    Tucker, G.C.4    Barritault, D.5    Thiery, J.P.6
  • 101
    • 12144286882 scopus 로고    scopus 로고
    • Mechanism in epithelial plasticity and metastasis: Insights from 3D cultures and expression profiling
    • M. Jechlinger, S. Grünert, and H. Beug Mechanism in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling J Mammary Gland Biol Neoplasia 7 2002 415 432
    • (2002) J Mammary Gland Biol Neoplasia , vol.7 , pp. 415-432
    • Jechlinger, M.1    Grünert, S.2    Beug, H.3
  • 102
    • 0029662049 scopus 로고    scopus 로고
    • TGF-beta and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
    • M. Oft, J. Peli, C. Rudaz, H. Schwarz, H. Beug, and E. Reichmann TGF-beta and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells Genes Dev 10 1996 2462 2477
    • (1996) Genes Dev , vol.10 , pp. 2462-2477
    • Oft, M.1    Peli, J.2    Rudaz, C.3    Schwarz, H.4    Beug, H.5    Reichmann, E.6
  • 103
    • 0034666839 scopus 로고    scopus 로고
    • Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: A mechanism leading to increased malignancy in epithelial cells
    • K. Lehmann, E. Janda, and C.E. Pierreux Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells Genes Dev 14 2000 2610 2622
    • (2000) Genes Dev , vol.14 , pp. 2610-2622
    • Lehmann, K.1    Janda, E.2    Pierreux, C.E.3
  • 104
    • 0037148532 scopus 로고    scopus 로고
    • Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: Dissection of Ras signaling pathways
    • E. Janda, K. Lehmann, and I. Killisch Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways J Cell Biol 156 2002 299 313
    • (2002) J Cell Biol , vol.156 , pp. 299-313
    • Janda, E.1    Lehmann, K.2    Killisch, I.3
  • 105
    • 0347052797 scopus 로고    scopus 로고
    • Molecular aspects of epithelial cell plasticity: Implications for local tumor invasion and metastasis
    • J. Gotzmann, M. Mikula, and A. Eger Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis Mutat Res 566 2004 9 20
    • (2004) Mutat Res , vol.566 , pp. 9-20
    • Gotzmann, J.1    Mikula, M.2    Eger, A.3
  • 106
    • 0033377979 scopus 로고    scopus 로고
    • Control of the cell cycle and apoptosis
    • A.S. Lundberg, and R.A. Weinberg Control of the cell cycle and apoptosis Eur J Cancer 35 1999 531 539
    • (1999) Eur J Cancer , vol.35 , pp. 531-539
    • Lundberg, A.S.1    Weinberg, R.A.2
  • 108
    • 1642278888 scopus 로고    scopus 로고
    • Collaborative activities of macrophage-stimulating protein and transforming growth factor-β1 in induction of epithelial to mesenchymal transition: Roles of the RON receptor tyrosine kinase
    • D. Wang, Q. Shen, Y.Q. Chen, and M.H. Wang Collaborative activities of macrophage-stimulating protein and transforming growth factor-β1 in induction of epithelial to mesenchymal transition: roles of the RON receptor tyrosine kinase Oncogene 23 2004 1668 1680
    • (2004) Oncogene , vol.23 , pp. 1668-1680
    • Wang, D.1    Shen, Q.2    Chen, Y.Q.3    Wang, M.H.4
  • 109
    • 0037572319 scopus 로고    scopus 로고
    • Tumor necrosis factor-α stimulates the epithelial-to-mesenchymal transition of human colonic organoids
    • R.C. Bates, and A.M. Mercurio Tumor necrosis factor-α stimulates the epithelial-to-mesenchymal transition of human colonic organoids Mol Biol Cell 14 2003 1790 1800
    • (2003) Mol Biol Cell , vol.14 , pp. 1790-1800
    • Bates, R.C.1    Mercurio, A.M.2
  • 110
    • 2342643464 scopus 로고    scopus 로고
    • β-Catenin and TGFβ signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition
    • A. Eger, A. Stockinger, and J. Park β-Catenin and TGFβ signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition Oncogene 23 2004 2672 2680
    • (2004) Oncogene , vol.23 , pp. 2672-2680
    • Eger, A.1    Stockinger, A.2    Park, J.3
  • 111
    • 0031817391 scopus 로고    scopus 로고
    • Transforming growth factor β is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumor invasion
    • G. Portella, S.A. Cumming, and J. Liddell Transforming growth factor β is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion Cell Growth Differ 9 1998 393 404
    • (1998) Cell Growth Differ , vol.9 , pp. 393-404
    • Portella, G.1    Cumming, S.A.2    Liddell, J.3
  • 112
    • 0036467496 scopus 로고    scopus 로고
    • TGFβ signaling: Positive and negative effects on tumorigenesis
    • L.M. Wakefield, and A.B. Roberts TGFβ signaling: positive and negative effects on tumorigenesis Curr Opin Genet Dev 12 2002 22 29
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 22-29
    • Wakefield, L.M.1    Roberts, A.B.2
  • 113
    • 0346725840 scopus 로고    scopus 로고
    • Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes
    • F. Valdés, M.M. Murillo, and A.M. Valverde Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes Exp Cell Res 292 2004 209 218
    • (2004) Exp Cell Res , vol.292 , pp. 209-218
    • Valdés, F.1    Murillo, M.M.2    Valverde, A.M.3
  • 114
    • 0028026665 scopus 로고
    • Receptor chimeras indicate that the met tyrosine kinase mediates the motility and morphogenic responses of hepatocyte growth/scatter factor
    • H. Zhu, M.A. Naujokas, and M. Park Receptor chimeras indicate that the met tyrosine kinase mediates the motility and morphogenic responses of hepatocyte growth/scatter factor Cell Growth Differ 5 1994 359 366
    • (1994) Cell Growth Differ , vol.5 , pp. 359-366
    • Zhu, H.1    Naujokas, M.A.2    Park, M.3
  • 115
    • 0036205178 scopus 로고    scopus 로고
    • The role of hepatocyte growth factor (scatter factor) in epithelial-mesenchymal transtion and breast cancer
    • B.E. Elliott, W.L. Hung, A.H. Boag, and A.B. Tuck The role of hepatocyte growth factor (scatter factor) in epithelial-mesenchymal transtion and breast cancer Can J Physiol Pharmacol 80 2002 91 102
    • (2002) Can J Physiol Pharmacol , vol.80 , pp. 91-102
    • Elliott, B.E.1    Hung, W.L.2    Boag, A.H.3    Tuck, A.B.4
  • 116
    • 0345736990 scopus 로고    scopus 로고
    • Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
    • Z. Lu, S. Ghosh, Z. Wang, and T. Hunter Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion Cancer Cell 4 2003 499 515
    • (2003) Cancer Cell , vol.4 , pp. 499-515
    • Lu, Z.1    Ghosh, S.2    Wang, Z.3    Hunter, T.4
  • 117
    • 0033957665 scopus 로고    scopus 로고
    • The catalytic activity of the Src family kinases is required to disrupt cadherin-dependent cell-cell contacts
    • D.W. Owens, G.W. McLean, and A.W. Wyke The catalytic activity of the Src family kinases is required to disrupt cadherin-dependent cell-cell contacts Mol Biol Cell 11 2000 51 64
    • (2000) Mol Biol Cell , vol.11 , pp. 51-64
    • Owens, D.W.1    McLean, G.W.2    Wyke, A.W.3
  • 118
    • 0032848957 scopus 로고    scopus 로고
    • Epithelial cell plasticity in development and tumor progression
    • J.P. Thiery, and D. Chopin Epithelial cell plasticity in development and tumor progression Cancer Metastasis Rev 18 1999 31 42
    • (1999) Cancer Metastasis Rev , vol.18 , pp. 31-42
    • Thiery, J.P.1    Chopin, D.2
  • 119
    • 0027410889 scopus 로고
    • The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells
    • K.M. Weidner, M. Sachs, and W. Birchmeier The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells J Cell Biol 121 1993 145 154
    • (1993) J Cell Biol , vol.121 , pp. 145-154
    • Weidner, K.M.1    Sachs, M.2    Birchmeier, W.3
  • 120
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • E.A. Clark, T.R. Golub, E.S. Lander, and R.O. Hynes Genomic analysis of metastasis reveals an essential role for RhoC Nature 406 2000 532 535
    • (2000) Nature , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 121
    • 5444230567 scopus 로고    scopus 로고
    • Transcriptional regulation of cadherins during development and carcinogenesis
    • H. Peinado, F. Portillo, and A. Cano Transcriptional regulation of cadherins during development and carcinogenesis Int J Dev Biol 48 2004 365 375
    • (2004) Int J Dev Biol , vol.48 , pp. 365-375
    • Peinado, H.1    Portillo, F.2    Cano, A.3
  • 122
    • 0037054937 scopus 로고    scopus 로고
    • Differential gene expression in breast cancer cell lines and stroma-tumor differences in microdissected breast cancer biopsies revealed by display array analysis
    • A.S. Mellick, C.J. Day, S.R. Weinstein, L.R. Griffiths, and N.A. Morrison Differential gene expression in breast cancer cell lines and stroma-tumor differences in microdissected breast cancer biopsies revealed by display array analysis Int J Cancer 100 2002 172 180
    • (2002) Int J Cancer , vol.100 , pp. 172-180
    • Mellick, A.S.1    Day, C.J.2    Weinstein, S.R.3    Griffiths, L.R.4    Morrison, N.A.5
  • 123
    • 0031426654 scopus 로고    scopus 로고
    • Matrix metalloproteinase stromelysin-1 triggers the cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells
    • A. Lochter, S. Galosy, J. Muschler, N. Freedman, Z. Werb, and M.J. Bissell Matrix metalloproteinase stromelysin-1 triggers the cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells J Cell Biol 139 1997 1861 1872
    • (1997) J Cell Biol , vol.139 , pp. 1861-1872
    • Lochter, A.1    Galosy, S.2    Muschler, J.3    Freedman, N.4    Werb, Z.5    Bissell, M.J.6
  • 124
    • 0033597726 scopus 로고    scopus 로고
    • The stromal proteinase MMP-3/stromelysin-1 promotes mammary carcinogenesis
    • M.D. Sternlicht, A. Lochter, and C.J. Sympson The stromal proteinase MMP-3/stromelysin-1 promotes mammary carcinogenesis Cell 98 1999 137 146
    • (1999) Cell , vol.98 , pp. 137-146
    • Sternlicht, M.D.1    Lochter, A.2    Sympson, C.J.3
  • 125
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • M. Egeblad, and Z. Werb New functions for the matrix metalloproteinases in cancer progression Nat Rev Cancer 2 2002 161 174
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 126
    • 0038744921 scopus 로고    scopus 로고
    • Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas
    • K. Yokoyama, N. Kamata, and R. Fujimoto Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas Int J Oncol 22 2003 891 898
    • (2003) Int J Oncol , vol.22 , pp. 891-898
    • Yokoyama, K.1    Kamata, N.2    Fujimoto, R.3
  • 127
    • 0034627772 scopus 로고    scopus 로고
    • Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity
    • A. Eger, A. Stockinger, B. Schaffhauser, H. Beug, and R. Foisner Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity J Cell Biol 148 2000 173 188
    • (2000) J Cell Biol , vol.148 , pp. 173-188
    • Eger, A.1    Stockinger, A.2    Schaffhauser, B.3    Beug, H.4    Foisner, R.5
  • 128
    • 0346102826 scopus 로고    scopus 로고
    • C-Jun and the dominant-negative mutant, TAM67, induce vimentin gene expression by interacting with the activator Sp1
    • Y. Wu, X. Zhang, and Z.E. Zehner c-Jun and the dominant-negative mutant, TAM67, induce vimentin gene expression by interacting with the activator Sp1 Oncogene 22 2003 8891 8901
    • (2003) Oncogene , vol.22 , pp. 8891-8901
    • Wu, Y.1    Zhang, X.2    Zehner, Z.E.3
  • 129
    • 4444319419 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis
    • R.C. Bates, M.J. DeLeo III, and A.M. Mercurio The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis Exp Cell Res 299 2004 315 324
    • (2004) Exp Cell Res , vol.299 , pp. 315-324
    • Bates, R.C.1    DeLeo III, M.J.2    Mercurio, A.M.3
  • 130
    • 0034798707 scopus 로고    scopus 로고
    • Leaving the neighborhood: Molecular mechanisms involved during epithelial-mesenchymal transition
    • P. Savagner Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition Bioessays 23 2001 912 923
    • (2001) Bioessays , vol.23 , pp. 912-923
    • Savagner, P.1
  • 131
    • 0030460634 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in cancer progression
    • C. Birchmeier, W. Birchmeier, and B. Brand-Saberi Epithelial-mesenchymal transitions in cancer progression Acta Anat 156 1996 217 226
    • (1996) Acta Anat , vol.156 , pp. 217-226
    • Birchmeier, C.1    Birchmeier, W.2    Brand-Saberi, B.3
  • 132
    • 0032843036 scopus 로고    scopus 로고
    • Caherins and catenins: Role in signal transduction and tumor progression
    • J. Behrens Caherins and catenins: role in signal transduction and tumor progression Cancer Metastasis Rev 18 1999 15 30
    • (1999) Cancer Metastasis Rev , vol.18 , pp. 15-30
    • Behrens, J.1
  • 133
    • 0031842760 scopus 로고    scopus 로고
    • The role of integrins in tumorigenesis and metastasis
    • R.J. Sanders, F. Mainiero, and F.G. Giancotti The role of integrins in tumorigenesis and metastasis Cancer Invest 16 1998 329 344
    • (1998) Cancer Invest , vol.16 , pp. 329-344
    • Sanders, R.J.1    Mainiero, F.2    Giancotti, F.G.3
  • 134
  • 135
    • 0031050310 scopus 로고    scopus 로고
    • Cytoskeletal and adhesion proteins as tumor suppressors
    • A. Ben-Ze'ev Cytoskeletal and adhesion proteins as tumor suppressors Curr Opin Cell Biol 9 1997 99 108
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 99-108
    • Ben-Ze'Ev, A.1
  • 136
    • 4944249069 scopus 로고    scopus 로고
    • Tumor-associated E-cadherin mutations do not induce Wnt target gene expression, but affect E-cadherin repressors
    • H. Laux, R. Tomer, and M.T. Mader Tumor-associated E-cadherin mutations do not induce Wnt target gene expression, but affect E-cadherin repressors Lab Invest 84 2004 1372 1386
    • (2004) Lab Invest , vol.84 , pp. 1372-1386
    • Laux, H.1    Tomer, R.2    Mader, M.T.3
  • 137
    • 0028603343 scopus 로고
    • TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
    • P.J. Miettinen, R. Ebner, A.R. Lopez, and R. Derynck TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors J Cell Biol 127 1994 2021 2036
    • (1994) J Cell Biol , vol.127 , pp. 2021-2036
    • Miettinen, P.J.1    Ebner, R.2    Lopez, A.R.3    Derynck, R.4
  • 138
    • 0036349710 scopus 로고    scopus 로고
    • Cell adhesion-mediated transformation of a human SCLC cell line is associated with the development of a normal phenotype
    • A.J. Gilchrist, R. Meuser, J. Turchinsky, A.R. Shaw, M. Pasdar, and W.T. Dixon Cell adhesion-mediated transformation of a human SCLC cell line is associated with the development of a normal phenotype Exp Cell Res 276 2002 63 78
    • (2002) Exp Cell Res , vol.276 , pp. 63-78
    • Gilchrist, A.J.1    Meuser, R.2    Turchinsky, J.3    Shaw, A.R.4    Pasdar, M.5    Dixon, W.T.6
  • 140
    • 0029791878 scopus 로고    scopus 로고
    • E-cadherin expression in human breast cancer cells suppress the development of osteolytic bone metastases in an experimental metastasis model
    • G. Mbalaviele, C.R. Dunstan, A. Sasaki, P.J. Williams, G.R. Mundy, and T. Yoneda E-cadherin expression in human breast cancer cells suppress the development of osteolytic bone metastases in an experimental metastasis model Cancer Res 56 1996 4063 4070
    • (1996) Cancer Res , vol.56 , pp. 4063-4070
    • Mbalaviele, G.1    Dunstan, C.R.2    Sasaki, A.3    Williams, P.J.4    Mundy, G.R.5    Yoneda, T.6
  • 141
    • 0029740376 scopus 로고    scopus 로고
    • Tumorigenicity, invasion and metastasis of the small cell lung cancer cell line NCI-H69 and two derivative lines MOG-H69V and MOG-H69VZ
    • M.Z. Khan, A.M. McNicol, and R.I. Freshney Tumorigenicity, invasion and metastasis of the small cell lung cancer cell line NCI-H69 and two derivative lines MOG-H69V and MOG-H69VZ Anticancer Res 16 1996 1659 1670
    • (1996) Anticancer Res , vol.16 , pp. 1659-1670
    • Khan, M.Z.1    McNicol, A.M.2    Freshney, R.I.3
  • 142
    • 0034710596 scopus 로고    scopus 로고
    • Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei
    • M.J. Munsie, A.E. Michalska, C.M. O'Brien, A.O. Trounson, M.F. Pera, and P.S. Mountford Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei Curr Biol 10 2000 989 992
    • (2000) Curr Biol , vol.10 , pp. 989-992
    • Munsie, M.J.1    Michalska, A.E.2    O'Brien, C.M.3    Trounson, A.O.4    Pera, M.F.5    Mountford, P.S.6
  • 143
    • 0035957754 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer
    • T. Wakayama, V. Tabar, I. Rodriguez, A.C.F. Perry, L. Studer, and P. Mombaerts Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer Science 292 2001 740 743
    • (2001) Science , vol.292 , pp. 740-743
    • Wakayama, T.1    Tabar, V.2    Rodriguez, I.3    Perry, A.C.F.4    Studer, L.5    Mombaerts, P.6
  • 144
    • 0035816538 scopus 로고    scopus 로고
    • Epigenetic instability in ES cells and cloned mice
    • D. Humpherys, K. Eggan, and H. Akutsu Epigenetic instability in ES cells and cloned mice Science 293 2001 95 97
    • (2001) Science , vol.293 , pp. 95-97
    • Humpherys, D.1    Eggan, K.2    Akutsu, H.3
  • 145
    • 0036792031 scopus 로고    scopus 로고
    • Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus nuclei
    • D. Humpherys, K. Eggan, and H. Akutsu Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus nuclei Proc Natl Acad Sci U S A 99 2002 12889 12894
    • (2002) Proc Natl Acad Sci U S a , vol.99 , pp. 12889-12894
    • Humpherys, D.1    Eggan, K.2    Akutsu, H.3
  • 146
    • 0037433659 scopus 로고    scopus 로고
    • Epigenetics and nuclear transfer
    • R. Alberio, and K.H.S. Campbell Epigenetics and nuclear transfer Lancet 361 9365 2003 1239 1240
    • (2003) Lancet , vol.361 , Issue.9365 , pp. 1239-1240
    • Alberio, R.1    Campbell, K.H.S.2
  • 147
    • 20444457636 scopus 로고    scopus 로고
    • Temporally controlled transgenic recombination with the SCL stem cell enhancer: Fate tracing embryonic hematopoietic stem cells into adulthood
    • J.R. Göthert, S.E. Gustin, A.R. Green, B. Göttgens, D.J. Izon, and C.G. Begley Temporally controlled transgenic recombination with the SCL stem cell enhancer: fate tracing embryonic hematopoietic stem cells into adulthood Onkologie 2 suppl 3 2004 53 54 Abstract 0412
    • (2004) Onkologie , vol.2 , Issue.3 SUPPL. , pp. 53-54
    • Göthert, J.R.1    Gustin, S.E.2    Green, A.R.3    Göttgens, B.4    Izon, D.J.5    Begley, C.G.6
  • 148
    • 0036838561 scopus 로고    scopus 로고
    • Identification of the hemangioblast in postnatal life
    • E. Pelosi, M. Valtieri, and S. Coppola Identification of the hemangioblast in postnatal life Blood 100 2002 3203 3208
    • (2002) Blood , vol.100 , pp. 3203-3208
    • Pelosi, E.1    Valtieri, M.2    Coppola, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.