Role of activin A in negative regulation of normal and tumor B lymphocytes

Journal of Leukocyte Biology

Volumn 69, Issue 6, 2001, Pages 867-873

  Zipori, D ^a   Barda Saad, M ^a  

^a Department of Molecular Cell Biology ^*  (Israel)

Author keywords

IL 6; Myeloma; Restrictins; Signal transduction

Indexed keywords

ACTIVIN A; INTERLEUKIN 6;

APOPTOSIS; B LYMPHOCYTE; CELL CYCLE; CELL GROWTH; CONFERENCE PAPER; GROWTH REGULATION; HEMATOPOIESIS; HUMAN; HUMAN CELL; LYMPHOCYTOPOIESIS; MESENCHYME; MYELOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ACTIVINS; APOPTOSIS; B-LYMPHOCYTES; BONE MARROW CELLS; CELL CYCLE; CELL DIFFERENTIATION; FOLLISTATIN; GLYCOPROTEINS; GROWTH INHIBITORS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; INHIBINS; INTERLEUKIN-6; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MODELS, BIOLOGICAL; MULTIPLE MYELOMA; NASAL POLYPS; SIGNAL TRANSDUCTION; STROMAL CELLS; TUMOR STEM CELLS;

EID: 0034973221     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (71)

1. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
2. The Bcl-2 protein family: Arbiters of cell survival
3. Apoptosis and T-cell repertoire selection in the thymus
4. Similar rates of production of T and B lymphocytes in the bone marrow
5. Restrictins: Stromal cell associated factors that control cell organization in hemopoietic tissues
6. In vitro proliferation of mouse lymphoblastoid cell lines: Growth modulation by various populations of adherent cells
7. Adherent cells from mouse bone marrow inhibit the formation of colony stimulating factor (CSF) induced myeloid colonies
8. Conditions required for the inhibition of in vitro growth of a mouse myeloma cell line by adherent bone-marrow cells
9. Myelopoiesis in the presence of stromal cells from mouse bone marrow: I. Monosaccharides regulate colony formation
10. Myelopoiesis in the presence of stromal cells from mouse bone marrow: II. Mechanism of glucose dependent colony formation
11. Phenotypic heterogeneity among stromal cell lines from mouse bone marrow disclosed in their extracellular matrix composition and interactions with normal and leukemic cells
12. Differentiation stage and lineage-specific inhibitor from the stroma of mouse bone marrow that restricts lymphoma cell growth
13. Selective accumulation of lymphocyte precursor cells mediated by stromal cells of hemopoietic origin
14. Multilineage hemopoiesis induced by cloned stromal cells
15. Alpha beta/gamma delta lineage commitment in the thymus of normal and genetically manipulated mice
16. Multilineage potential of adult human mesenchymal stem cells
17. Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model
18. Cardiomyocytes can be generated from marrow stromal cells in vitro
19. Bone marrow as a potential source of hepatic oval cells
20. Modulation of hemopoiesis by novel stromal cell factors
21. Stromal cells from the bone marrow: Evidence for a restrictive role in regulation of hemopoiesis
22. Role of stromal cell factors (restrictins) in microorganization of hemopoietic tissues
23. Regulation of hemopoiesis by cytokines that restrict options for growth and differentiation
24. The renewal and differentiation of hemopoietic stem cells
25. Stromal cells of hemopoietic origin
26. Growth restrictions in the regulation of haemopoiesis
27. The negative regulation of hematopoiesis
28. Regulation of haemopoietic stem cell proliferation in long term bone marrow cultures
29. Stem cell culture
30. Transforming growth factor-beta: Pleiotropic role in the regulation of hematopoiesis
31. The plasmacytoma growth inhibitor restrictin-P is an antagonist of interleukin 6 and interleukin 11: Identification as a stroma-derived activin A
32. Restrictin-P/stromal activin A, kills its target cells via an apoptotic mechanism
33. The promotion of plasmacytoma tumor growth by mesenchymal stroma is antagonized by basis fibroblast growth factor induced activin A
34. Importance of FSH-releasing protein and inhibin in erythrodifferentiation
35. Chemical and biological characterization of the inhibin family of protein hormones
36. r 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone
37. Follistatins: More than follicle-stimulating hormone suppressing proteins
38. Activin A induces apoptotic cell death
39. Involvement of p21 (WAF1/ Cip1), CDK4 and Rb in activin A mediated signaling leading to hepatoma cell growth inhibition
40. Smad7 is an activin-inducible inhibitor of activin-induced growth arrest and apoptosis in mouse B cells
41. Smad proteins suppress C/EBPβ and STAT3 mediated transcriptional activation of the haptoglobin promoter
42. Purification and characterization of erythroid differentiation factor (EDF) isolated from human leukemia cell line THP-1
43. Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin beta A chain
44. Selective and indirect modulation of human multipotential and erythroid hematopoietic progenitor cell proliferation by recombinant human activin and inhibin
45. Characterization of the potentiation effect of activin on human erythroid colony formation in vitro
46. Effects of erythroid differentiation factor (EDF) on proliferation and differentiation of human hematopoietic progenitors
47. Effect of erythroid differentiation factor on maintenance of human hematopoietic cells in co-cultures with allogenic stromal cells
48. Detection of functional and dimeric activin A in human marrow microenvironment: Implications for the modulation of erythropoiesis
49. Control of stroma-dependent hemopoiesis by basic fibroblast growth factor: Stromal phenotypic plasticity and modified myelopoietic functions
50. Epidemiology of nasal polyps
51. Granulocyte/macrophage colony-stimulating factor (GM-CSF) gene expression by eosinophils in nasal polyposis
52. Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1)
53. Expression of transforming growth factors-alpha and beta 1 messenger RNA and product by eosinophils in nasal polyps
54. Cytokine gene expression and release from epithelial cells: A comparison study between healthy nasal mucosa and nasal polyps
55. Eosinophil expression of transforming growth factor-beta and its receptors in nasal polyposis: Role of the cytokines in this disease process
56. Myofibroblast accumulation induced by transforming growth factor-beta is involved in the pathogenesis of nasal polyps
57. Expression of the transforming growth factor beta isoforms in inflammatory cells of nasal polyps
58. Expression of basic fibroblast growth factor in nasal polyps
59. Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells
60. Transforming growth factor-alpha and rhinitis
61. Expression of RANTES by IL-1 beta and TNF-alpha stimulated nasal polyp fibroblasts
62. Effect of prednisolone on cytokine synthesis in nasal polyps
63. Inflammatory cells as well as epithelial cells in nasal polyps express vascular endothelial growth factor
64. Morphogen gradients: A question of time or concentration?
65. Activin signalling and response to a morphogen gradient
66. Activin has direct long-range signaling activity and can form a concentration gradient by diffusion
67. The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors
68. The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse
69. The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice
70. Limitin: An interferon-like cytokine that preferentially influences B-lymphocyte precursors
71. WECHE: A novel hematopoietic regulatory factor