CD34+CD38- hematopoietic precursors derived from human embryonic stem cells exhibit an embryonic gene expression pattern

Blood

Volumn 103, Issue 11, 2004, Pages 4134-4141

  Lu, Shi Jiang ^a   Li, Fei ^a   Vida, Loyda ^a   Honig, George R ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; CD34 ANTIGEN; CD38 ANTIGEN; EPSILON GLOBIN; FLT3 LIGAND; GLOBIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW CELL; CELL ISOLATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DNA MICROARRAY; EMBRYO; FETUS LIVER; GENE EXPRESSION; GENE OVEREXPRESSION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; UNINDEXED SEQUENCE; YOLK SAC;

EID: 2542418035     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-10-3575     Document Type: Article

References (49)

1. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature. 1981;292:154-156.
2. Thomson JA, Kalishman J, Golos TG, et al. Isolation of a primate embryonic stem cell line. Proc Natl Acad Sci U S A. 1995;92:7844-7848.
3. Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998;282:1145-1147.
4. Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat Biotechnol. 2000;18:399-404.
5. Li F, Lu S-J, Vida L, Thomson JA, Honig GR. Bone morphogenetic protein-4 induces efficient hematopoietic differentiation of rhesus monkey embryonic stem cells in vitro. Blood. 2001;98:335-342.
6. Chadwick K, Wang L, Li L, et al. Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood. 2003;102:906-915.
7. Kaufman DS, Hanson ET, Lewis RL, Auerbach R, Thomson JA. Hematopoietic colony-forming cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A. 2001;98:10716-10721.
8. Hole N, Graham GJ, Menzel U, Ansell JD. A limited temporal window for the derivation of multilineage repopulating hematopoietic progenitors during embryonal stem cell differentiation in vitro. Blood. 1996;88:1266-1276.
9. Palacios R, Golunski E, Samaridis J. In vitro generation of hematopoietic stem cells from an embryonic stem cell line. Proc Natl Acad Sci U S A. 1995;92:7530-7534.
10. Yoder MC, Hiatt K, Dutt P, Mukherjee P, Bodine DM, Orlic D. Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity. 1997;7:335-344.
11. Yoder MC, Hiatt K, Mukherjee P. In vivo repopulating hematopoietic stem cells are present in the murine yolk sac at day 9.0 postcoitus. Proc Natl Acad Sci U S A. 1997;94:6776-6780.
12. Yoder MC, Hiatt K. Engraftment of embryonic hematopoietic cells in conditioned newborn recipients. Blood. 1997;89:2176-2183.
13. Lu S-J, Li F, Vida L, Honig GR. Comparative gene expression in hematopoietic progenitor cells derived from embryonic stem cells. Exp Hematol. 2002;30:58-66.
14. Lu S-J, Quan C, Li F, Vida L, Honig GR. Hematopoietic progenitor cells derived from embryonic stem cells: analysis of gene expression. Stem Cells. 2002;20:428-437.
15. Honig GR, Li F, Lu S-J, Vida L. Hematopoietic differentiation of rhesus monkey embryonic stem cells. Blood Cells Mol Dis. 2004;32:5-10.
16. Zhumabayeva B, Diatchenko L, Chenchik A, Siebert PD. Use of SMART-generated cDNA for gene expression studies in multiple human tumors. Biotechniques. 2001;30:158-163.
17. Wang J, Hu L, Hamilton SR, Coombes KR, Zhang W. RNA amplification strategies for cDNA microarray experiments. Biotechniques. 2003;34:394-400.
18. Ida H, Boylan SA, Weigel AL, Hjelmeland LM. Age-related changes in the transcriptional profile of mouse RPE/choroid. Physiol Genomics. 2003;15:258-262.
19. Seth D, Gorrell MD, McGuinness PH, et al. SMART amplification maintains representation of relative gene expression: quantitative validation by real time PCR and application to studies of alcoholic liver disease in primates. J Biochem Biophys Methods. 2003;55:53-66.
20. Zheng J, Shen W, He DZ, Long KB, Madison LD, Dallos P. Prestin is the motor protein of cochlear outer hair cells. Nature. 2000;405:149-155,
21. Terskikh AV, Miyamoto T, Chang C, Diatchenko L, Weissman IL. Gene expression analysis of purified hematopoietic stem cells and committed progenitors. Blood. 2003;102:94-101.
22. Quan C, Lu SJ. Identification of genes preferentially expressed in mammary epithelial cells of Copenhagen rat using subtractive hybridization and microarrays. Carcinogenesis. 2003;24:1593-1599.
23. Akashi K, He X, Chen J, et al. Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood. 2003;10t:383-389.
24. Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science. 2002;298:597-600.
25. Ivanova NB, Dimos JT, Schaniel C, Hackney JA, Moore KA, Lemischka IR. A stem cell molecular signature. Science. 2002;298:601-604.
26. Billia F, Barbara M, McEwen J, Trevisan M, Iscove NN. Resolution of pluripotential intermediates in murine hematopoietic differentiation by global complementary DNA amplification from single cells: confirmation of assignments by expression profiling of cytokine receptor transcripts. Blood. 2001;97:2257-2268.
27. Peschle C, Migliaccio AR, Migliaccio G, et al. Embryonic-fetal Hb switch in humans: studies on erythroid bursts generated by embryonic progenitors from yolk sac and liver. Proc Natl Acad Sci U S A. 1984;81:2416-2420.
28. Bodger MP, Izaguirre CA, Blacklock HA, Hoffbrand AV. Surface antigenic determinants on human pluripotent and unipotent hematopoietic progenitor cells. Blood. 1983;61:1006-1010.
29. Katz FE, Davis L, Myers CD, Greaves MF. Selective expression of class-II MHC antigens during hemopoietic differentiation. Exp Hematol. 1985;13:1182-1187.
30. Jurisicova A, Casper RF, MacLusky NJ, Mills GB, Librach CL. HLA-G expression during preimplantation human embryo development. Proc Natl Acad Sci U S A. 1996;93:161-165.
31. Gabbianelli M, Boccoli G, Cianetti L, Russo G, Testa U, Peschle C. HLA expression in hemopoietic development. Class I and II antigens are induced in the definitive erythroid lineage and differentially modulated by fetal liver cytokines. J Immunol. 1990;144:3354-3360.
32. Gabbianelli M, Boccoli G, Petti S, et al. Expression and in-vitro modulation of HLA antigens in ontogenic development of human hemopoietic system. Ann N Y Acad Sci. 1987;511:138-147.
33. Desoye G, Dohr GA, Ziegler A. Expression of human major histocompatibility antigens on germ cells and early preimplantation embryos. Lab Invest. 1991;64:306-312.
34. Drukker M, Katz G, Urbach A, et al. Characterization of the expression of MHC proteins in human embryonic stem cells. Proc Natl Acad Sci U S A. 2002;99:9864-9869.
35. Rosnet O, Schiff C, Pebusque MJ, et al. Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells. Blood. 1993;82:1110-1119.
36. Matthews W, Jordan CT, Wiegand GW, Pardoll D, Lemischka IR. A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations. Cell. 1991;65:1143-1152.
37. Lyman SD, Jacobsen SE. c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities. Blood. 1998;91:1101-1134.
38. Gilliland DG, Griffin JD. The roles of FLT3 in hematopoiesis and leukemia. Blood. 2002;100:1532-1542.
39. Bouscary D, Pene F, Claessens YE, et al. Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation. Blood. 2003;101:3436-3443.
40. Chan RJ, Johnson SA, Li Y, Yoder MC, Feng GS. A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Blood. 2003;102:2074-2080.
41. Gomez M, Kioussis D, Cantrell DA. The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection. Immunity. 2001;15:703-713.
42. Gomez M, Tybulewicz V, Cantrell DA. Control of pre-T cell proliferation and differentiation by the GTPase Rac-I. Nat Immunol. 2000;1:348-352.
43. Adolfsson J, Borge OJ, Bryder D, et al. Upregulation of Flt3 expression within the bone marrow Lin(-)Scal (+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity. 2001;15:659-669.
44. Adolfsson J, Bryder D, Sitnicka E, Jacobsen SE. Expression of the flt3 tyrosine kinase receptor within the Lin-Scal +Kit+ stem cell compartment defines a lineage restricted repopulating progenitor/stem cell: evidence for loss of megakaryocyte and erythroid potential through flt3 signaling [abstract]. Blood. 2002;100:511a.
45. Christensen JL, Weissman IL. Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells. Proc Natl Acad Sci U S A. 2001;98:14541-14546.
46. Manz M, Karsunky H, Merad M, Cozzio A, Weissman IL. Flk2/Flt3 receptor expression at defined stages of early hematopoietic development and expansion of progenitors and downstream dentritic cells through cognate ligand stimulation. Blood [abstract]. 2002;100:290a.
47. Zeigler FC, Bennett BD, Jordan CT, et al. Cellular and molecular characterization of the role of the flk-2/fit-3 receptor tyrosine kinase in hematopoietic stem cells. Blood. 1994;84:2422-2430.
48. + hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells. Blood. 2003;102:881-886.
49. - cells expressing Flk2/Flt3. Br J Haematol. 2002;119:525-534.