-
1
-
-
0031664150
-
IL-4: Role in disease and regulation of production
-
CHOI, P., and H. REISER. 1998. IL-4: role in disease and regulation of production [editorial]. Clin Exp Immunol 113: 317.
-
(1998)
Clin Exp Immunol
, vol.113
, pp. 317
-
-
Choi, P.1
Reiser, H.2
-
2
-
-
0025764757
-
Interleukin-4: A prototypic immunoregulatory lymphokine
-
PAUL, W. E. 1991. Interleukin-4: a prototypic immunoregulatory lymphokine. Blood 77: 1859.
-
(1991)
Blood
, vol.77
, pp. 1859
-
-
Paul, W.E.1
-
3
-
-
0027248910
-
Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10
-
BOGDAN, C., and C. NATHAN. 1993. Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10. Ann N Y Acad Sci 685: 713.
-
(1993)
Ann N Y Acad Sci
, vol.685
, pp. 713
-
-
Bogdan, C.1
Nathan, C.2
-
4
-
-
0025133974
-
Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism
-
SADICK, M. D., F. P. HEINZEL, B. J. HOLADAY, R. T. PU, R. S. DAWKINS, and R. M. LOCKSLEY. 1990. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. J Exp Med 171: 115.
-
(1990)
J Exp Med
, vol.171
, pp. 115
-
-
Sadick, M.D.1
Heinzel, F.P.2
Holaday, B.J.3
Pu, R.T.4
Dawkins, R.S.5
Locksley, R.M.6
-
5
-
-
0026708759
-
Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis
-
ROMANI, L., A. MENCACCI, U. GROHMANN, S. MOCCI, P. MOSCI, P. PUCCETTI, and F. BISTONI. 1992. Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis. J Exp Med 176: 19.
-
(1992)
J Exp Med
, vol.176
, pp. 19
-
-
Romani, L.1
Mencacci, A.2
Grohmann, U.3
Mocci, S.4
Mosci, P.5
Puccetti, P.6
Bistoni, F.7
-
6
-
-
0028048136
-
Recombinant soluble interleukin-4 (IL-4) receptor acts as an antagonist of IL-4 in murine cutaneous Leishmaniasis
-
GESSNER, A., K. SCHROPPEL, A. WILL, K. H. ENSSLE, L. LAUFFER, and M. ROLLINGHOFF. 1994. Recombinant soluble interleukin-4 (IL-4) receptor acts as an antagonist of IL-4 in murine cutaneous Leishmaniasis. Infect Immun 62: 4112.
-
(1994)
Infect Immun
, vol.62
, pp. 4112
-
-
Gessner, A.1
Schroppel, K.2
Will, A.3
Enssle, K.H.4
Lauffer, L.5
Rollinghoff, M.6
-
7
-
-
0028305303
-
Cure of murine candidiasis by recombinant soluble interleukin-4 receptor
-
PUCCETTI, P., A. MENCACCI, E. CENCI, R. SPACCAPELO, P. MOSCI, K. H. ENSSLE, L. ROMANI, and F. BISTONI. 1994. Cure of murine candidiasis by recombinant soluble interleukin-4 receptor. J Infect Dis 169: 1325.
-
(1994)
J Infect Dis
, vol.169
, pp. 1325
-
-
Puccetti, P.1
Mencacci, A.2
Cenci, E.3
Spaccapelo, R.4
Mosci, P.5
Enssle, K.H.6
Romani, L.7
Bistoni, F.8
-
8
-
-
0027452977
-
Disruption of the murine IL-4 gene blocks Th2 cytokine responses
-
KOPF, M., G. LE GROS, M. BACHMANN, M. C. LAMERS, H. BLUETHMANN, and G. KOHLER. 1993. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 362: 245.
-
(1993)
Nature
, vol.362
, pp. 245
-
-
Kopf, M.1
Gros, G.L.E.2
Bachmann, M.3
Lamers, M.C.4
Bluethmann, H.5
Kohler, G.6
-
9
-
-
0031906015
-
The Th1/Th2 paradigm and experimental murine leishmaniasis
-
LOHOFF, M., A. GESSNER, C. BOGDAN, and M. RÖLLINGHOFF. 1998. The Th1/Th2 paradigm and experimental murine leishmaniasis. Int Arch Allergy Immunol 115: 191.
-
(1998)
Int Arch Allergy Immunol
, vol.115
, pp. 191
-
-
Lohoff, M.1
Gessner, A.2
Bogdan, C.3
Röllinghoff, M.4
-
10
-
-
1842417145
-
Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice
-
ERB, K. J., B. RUGER, M. VON BREVERN, B. RYFFEL, A. SCHIMPL, and K. RIVETT. 1997. Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice. J Exp Med 185: 329.
-
(1997)
J Exp Med
, vol.185
, pp. 329
-
-
Erb, K.J.1
Ruger, B.2
Von Brevern, M.3
Ryffel, B.4
Schimpl, A.5
Rivett, K.6
-
11
-
-
0029847368
-
Functional diversity of helper T lymphocytes
-
ABBAS, A. K., K. M. MURPHY, and A. SHER. 1996. Functional diversity of helper T lymphocytes. Nature 383: 787.
-
(1996)
Nature
, vol.383
, pp. 787
-
-
Abbas, A.K.1
Murphy, K.M.2
Sher, A.3
-
12
-
-
0028037782
-
Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
-
CHEN, Y., V. K. KUCHROO, J. INOBE, D. A. HAFLER, and H. L. WEINER. 1994. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265: 1237.
-
(1994)
Science
, vol.265
, pp. 1237
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.A.4
Weiner, H.L.5
-
13
-
-
0031036084
-
Interleukin-4 protects against a genetically linked lupus-like autoimmune syndrome
-
SANTIAGO, M. L., L. FOSSATI, C. JACQUET, W. MULLER, S. IZUI, and L. REININGER. 1997. Interleukin-4 protects against a genetically linked lupus-like autoimmune syndrome. J Exp Med 185: 65.
-
(1997)
J Exp Med
, vol.185
, pp. 65
-
-
Santiago, M.L.1
Fossati, L.2
Jacquet, C.3
Muller, W.4
Izui, S.5
Reininger, L.6
-
14
-
-
0024559126
-
A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes
-
BROWN, K. D., S. M. ZURAWSKI, T. R. MOSMANN, and G. ZURAWSKI. 1989. A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes. J Immunol 142: 679.
-
(1989)
J Immunol
, vol.142
, pp. 679
-
-
Brown, K.D.1
Zurawski, S.M.2
Mosmann, T.R.3
Zurawski, G.4
-
15
-
-
0032909720
-
IL-13 production by NK cells: IL-13-producing NK and T cells are present in vivo in the absence of IFN-gamma
-
HOSHINO, T., R. T. WINKLER-PICKETT, A. T. MASON, J. R. ORTALDO, and H. A. YOUNG. 1999. IL-13 production by NK cells: IL-13-producing NK and T cells are present in vivo in the absence of IFN-gamma. J Immunol 162: 51.
-
(1999)
J Immunol
, vol.162
, pp. 51
-
-
Hoshino, T.1
Winkler-Pickett, R.T.2
Mason, A.T.3
Ortaldo, J.R.4
Young, H.A.5
-
16
-
-
0027522374
-
Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells
-
PUNNONEN, J., G. AVERSA, B. G. COCKS, A. N. MCKENZIE, S. MENON, G. ZURAWSKI, R. DE WAAL MALEFYT, and J. E. DE VRIES. 1993. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci U S A 90: 3730.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 3730
-
-
Punnonen, J.1
Aversa, G.2
Cocks, B.G.3
McKenzie, A.N.4
Menon, S.5
Zurawski, G.6
De Malefyt, R.W.7
De Vries, J.E.8
-
17
-
-
0032545213
-
Interleukin-13: Central mediator of allergic asthma
-
WILLS-KARP, M., J. LUYIMBAZI, X. XU, B SCHOFIELD., T. Y. NEBEN, C. L. KARP, and D. D. DONALDSON. 1998. Interleukin-13: central mediator of allergic asthma [see comments]. Science 282: 2258.
-
(1998)
Science
, vol.282
, pp. 2258
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
Schofield, B.4
Neben, T.Y.5
Karp, C.L.6
Donaldson, D.D.7
-
18
-
-
0032545433
-
Requirement for IL-13 independently of IL-4 in experimental asthma
-
GRUNIG, G., M. WARNOCK, A. E. WAKIL, R. VENKAYYA, F. BROMBACHER, D. M. RENNICK, D. SHEPPARD, M. MOHRS, D. D. DONALDSON, R. M. LOCKSLEY, and D. B. CORRY. 1998. Requirement for IL-13 independently of IL-4 in experimental asthma [see comments]. Science 282: 2261.
-
(1998)
Science
, vol.282
, pp. 2261
-
-
Grunig, G.1
Warnock, M.2
Wakil, A.E.3
Venkayya, R.4
Brombacher, F.5
Rennick, D.M.6
Sheppard, D.7
Mohrs, M.8
Donaldson, D.D.9
Locksley, R.M.10
Corry, D.B.11
-
19
-
-
0023858087
-
Expression of high affinity receptors for murine interleukin 4 (BSF-1) on hemopoietic and nonhemopoietic cells
-
LOWENTHAL, J. W., B. E. CASTLE, J. CHRISTIANSEN, J. SCHREURS, D. RENNICK, N. ARAI, P. HOY, Y. TAKEBE, and M. HOWARD. 1988. Expression of high affinity receptors for murine interleukin 4 (BSF-1) on hemopoietic and nonhemopoietic cells. J Immunol 140: 456.
-
(1988)
J Immunol
, vol.140
, pp. 456
-
-
Lowenthal, J.W.1
Castle, B.E.2
Christiansen, J.3
Schreurs, J.4
Rennick, D.5
Arai, N.6
Hoy, P.7
Takebe, Y.8
Howard, M.9
-
20
-
-
0024317761
-
The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms
-
MOSLEY, B., M. P. BECKMANN, C. J. MARCH, R. L. IDZERDA, S. D. GIMPEL, T. VANDENBOS, D. FRIEND, A. ALPERT, D. ANDERSON, J., JACKSON and et al. 1989. The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms. Cell 59: 335.
-
(1989)
Cell
, vol.59
, pp. 335
-
-
Mosley, B.1
Beckmann, M.P.2
March, C.J.3
Idzerda, R.L.4
Gimpel, S.D.5
Vandenbos, T.6
Friend, D.7
Alpert, A.8
Anderson, D.9
-
21
-
-
0025165027
-
Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding
-
HARADA, N., B. E. CASTLE, D. M. GORMAN, N. ITOH, J. SCHREURS, R. L. BARRETT, M. HOWARD, and A. MIYAJIMA. 1990. Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding. Proc Natl Acad Sci U S A 87: 857.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 857
-
-
Harada, N.1
Castle, B.E.2
Gorman, D.M.3
Itoh, N.4
Schreurs, J.5
Barrett, R.L.6
Howard, M.7
Miyajima, A.8
-
22
-
-
0025305497
-
Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily
-
IDZERDA, R. L., C. J. MARCH, B. MOSLEY, S. D. LYMAN, T. VANDEN BOS, S. D. GIMPEL, W. S. DIN, K. H. GRABSTEIN, M. B. WIDMER, L. S. PARK, and et al. 1990. Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily. J Exp Med 171: 861.
-
(1990)
J Exp Med
, vol.171
, pp. 861
-
-
Idzerda, R.L.1
March, C.J.2
Mosley, B.3
Lyman, S.D.4
Vanden Bos, T.5
Gimpel, S.D.6
Din, W.S.7
Grabstein, K.H.8
Widmer, M.B.9
Park, L.S.10
-
23
-
-
0025376201
-
Molecular cloning of a cDNA encoding the human interleukin 4 receptor
-
GALIZZI, J. P., C. E. ZUBER, N. HARADA, D. M. GORMAN, O. DJOSSOU, R. KASTELEIN, J. BANCHEREAU, M. HOWARD, and A. MIYAJIMA. 1990. Molecular cloning of a cDNA encoding the human interleukin 4 receptor. Int Immunol 2: 669.
-
(1990)
Int Immunol
, vol.2
, pp. 669
-
-
Galizzi, J.P.1
Zuber, C.E.2
Harada, N.3
Gorman, D.M.4
Djossou, O.5
Kastelein, R.6
Banchereau, J.7
Howard, M.8
Miyajima, A.9
-
24
-
-
0033574713
-
Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface
-
HAGE, T., W. SEBALD, and P. REINEMER. 1999. Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface. Cell 97: 271.
-
(1999)
Cell
, vol.97
, pp. 271
-
-
Sebald, W.1
Reinemer, P.2
-
25
-
-
0027731604
-
Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4
-
KONDO, M., T TAKESHITA., N. ISHII, M. NAKAMURA, S. WATANABE, K. ARAI, and K. SUG-AMURA. 1993. Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4 [see comments]. Science 262: 1874.
-
(1993)
Science
, vol.262
, pp. 1874
-
-
Kondo, M.1
Takeshita, T.2
Ishii, N.3
Nakamura, M.4
Watanabe, S.5
Arai, K.6
Sug-Amura, K.7
-
26
-
-
0028952380
-
Involvement of the interleukin-2 receptor gamma subunit in interleukin-4-dependent activation of mouse hematopoietic cells and splenic B cells
-
WATANABE, S., M. KONDO, K. TAKATSU, K. SUGAMURA, and K. ARAI. 1995. Involvement of the interleukin-2 receptor gamma subunit in interleukin-4-dependent activation of mouse hematopoietic cells and splenic B cells. Eur J Immunol 25: 126.
-
(1995)
Eur J Immunol
, vol.25
, pp. 126
-
-
Watanabe, S.1
Kondo, M.2
Takatsu, K.3
Sugamura, K.4
Arai, K.5
-
27
-
-
0028978898
-
The common gamma-chain for multiple cytokine receptors
-
SUGAMURA, K., H. ASAO, M. KONDO, N. TANAKA, N. ISHII, M. NAKAMURA, and T. TAKESHITA. 1995. The common gamma-chain for multiple cytokine receptors. Adv Immunol 59: 225.
-
(1995)
Adv Immunol
, vol.59
, pp. 225
-
-
Sugamura, K.1
Asao, H.2
Kondo, M.3
Tanaka, N.4
Ishii, N.5
Nakamura, M.6
Takeshita, T.7
-
28
-
-
0027403374
-
Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans
-
NOGUCHI, M., H. YI, H. M. ROSENBLATT, A. H. FILIPOVICH, S. ADELSTEIN, W. S. MODI, O. W. MCBRIDE, and W. J. LEONARD. 1993. Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 73: 147.
-
(1993)
Cell
, vol.73
, pp. 147
-
-
Noguchi, M.1
Yi, H.2
Rosenblatt, H.M.3
Filipovich, A.H.4
Adelstein, S.5
Modi, W.S.6
McBride, O.W.7
Leonard, W.J.8
-
29
-
-
0028878330
-
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain
-
DISANTO, J. P., W. MULLER, D. GUY-GRAND, A. FISCHER, and K. RAJEWSKY. 1995. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain. Proc Natl Acad Sci U S A 92: 377.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 377
-
-
Disanto, J.P.1
Muller, W.2
Guy-Grand, D.3
Fischer, A.4
Rajewsky, K.5
-
30
-
-
0028925778
-
Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain
-
CAO, X., E. W. SHORES, J. HU-LI, M. R. ANVER, B. L. KELSALL, S. M. RUSSELL, J. DRAGO, M. NOGUCHI, A GRINBERG., E. T. BLOOM, and et al. 1995. Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. Immunity 2: 223.
-
(1995)
Immunity
, vol.2
, pp. 223
-
-
Cao, X.1
Shores, E.W.2
Hu-Li, J.3
Anver, M.R.4
Kelsall, B.L.5
Russell, S.M.6
Drago, J.7
Noguchi, M.8
Grinberg, A.9
Bloom, E.T.10
-
31
-
-
0029924265
-
The molecular basis of X-linked severe combined immunodeficiency: Defective cytokine receptor signaling
-
LEONARD, W. J. 1996. The molecular basis of X-linked severe combined immunodeficiency: defective cytokine receptor signaling. Annu Rev Med 47: 229.
-
(1996)
Annu Rev Med
, vol.47
, pp. 229
-
-
Leonard, W.J.1
-
32
-
-
0028797453
-
Function of the interleukin-2 (IL-2) receptor gamma-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15
-
MATTHEWS, D. J., P. A. CLARK, J. HERBERT, G. MORGAN, R. J. ARMITAGE, C. KINNON, A. MINTY, K. H. GRABSTEIN, D CAPUT., P. FERRARA, and et al. 1995. Function of the interleukin-2 (IL-2) receptor gamma-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15. Blood 85: 38.
-
(1995)
Blood
, vol.85
, pp. 38
-
-
Matthews, D.J.1
Clark, P.A.2
Herbert, J.3
Morgan, G.4
Armitage, R.J.5
Kinnon, C.6
Minty, A.7
Grabstein, K.H.8
Caput, D.9
Ferrara, P.10
-
33
-
-
0031033551
-
X-SCID B cell responses to interleukin-4 and interleukin-13 are mediated by a receptor complex that includes the interleukin-4 receptor alpha chain (p140) but not the gamma c chain
-
MATTHEWS, D. J., L. HIBBERT, K. FRIEDRICH, A. MINTY, and R. E. CALLARD. 1997. X-SCID B cell responses to interleukin-4 and interleukin-13 are mediated by a receptor complex that includes the interleukin-4 receptor alpha chain (p140) but not the gamma c chain. Eur J Immunol 27: 116.
-
(1997)
Eur J Immunol
, vol.27
, pp. 116
-
-
Matthews, D.J.1
Hibbert, L.2
Friedrich, K.3
Minty, A.4
Callard, R.E.5
-
34
-
-
0029927153
-
Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain
-
CAPUT, D., P. LAURENT, M. KAGHAD, J. M. LELIAS, S. LEFORT, N. VITA, and P. FERRARA. 1996. Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain. J Biol Chem 271: 16921.
-
(1996)
J Biol Chem
, vol.271
, pp. 16921
-
-
Caput, D.1
Laurent, P.2
Kaghad, M.3
Lelias, J.M.4
Lefort, S.5
Vita, N.6
Ferrara, P.7
-
35
-
-
0030068217
-
Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
-
HILTON, D. J., J. G. ZHANG, D. METCALF, W. S. ALEXANDER, N. A. NICOLA, and T. A. WILLSON. 1996. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc Natl Acad Sci U S A 93: 497.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 497
-
-
Hilton, D.J.1
Zhang, J.G.2
Metcalf, D.3
Alexander, W.S.4
Nicola, N.A.5
Willson, T.A.6
-
36
-
-
0031015594
-
Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex
-
MILOUX, B., P LAURENT., O. BONNIN, J. LUPKER, D. CAPUT, N. VITA, and P. FERRARA. 1997. Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex. FEBS Lett 401: 163.
-
(1997)
FEBS Lett
, vol.401
, pp. 163
-
-
Miloux, B.1
Laurent, P.2
Bonnin, O.3
Lupker, J.4
Caput, D.5
Vita, N.6
Ferrara, P.7
-
37
-
-
0028962572
-
The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
-
LIN, J. X., T. S. MIGONE, M. TSANG, M. FRIEDMANN, J. A. WEATHERBEE, L. ZHOU, A. YAMAUCHI, E. T. BLOOM, J. MIETZ, S. JOHN, and et al. 1995. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 2: 331.
-
(1995)
Immunity
, vol.2
, pp. 331
-
-
Lin, J.X.1
Migone, T.S.2
Tsang, M.3
Friedmann, M.4
Weatherbee, J.A.5
Zhou, L.6
Yamauchi, A.7
Bloom, E.T.8
Mietz, J.9
John, S.10
-
38
-
-
0028126979
-
Design of human interleukin-4 antagonists inhibiting interleukin-4-dependent and interleukin-13-dependent responses in T-cells and B-cells with high efficiency
-
TONY, H. P., B. J. SHEN, P. REUSCH, and W. SEBALD. 1994. Design of human interleukin-4 antagonists inhibiting interleukin-4-dependent and interleukin-13-dependent responses in T-cells and B-cells with high efficiency. Eur J Biochem 225: 659.
-
(1994)
Eur J Biochem
, vol.225
, pp. 659
-
-
Tony, H.P.1
Shen, B.J.2
Reusch, P.3
Sebald, W.4
-
39
-
-
0027435159
-
An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: Support for a common component shared by IL-4 and IL-13 receptors
-
AVERSA, G., J. PUNNONEN, B. G. COCKS, R. DE WAAL MALEFYT, F., JR. VEGA, S. M. ZURAWSKI, G. ZURAWSKI, and J. E. DE VRIES. 1993. An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors. J Exp Med 178: 2213.
-
(1993)
J Exp Med
, vol.178
, pp. 2213
-
-
Aversa, G.1
Punnonen, J.2
Cocks, B.G.3
De Malefyt, R.W.4
Vega F., Jr.5
Zurawski, S.M.6
Zurawski, G.7
De Vries, J.E.8
-
40
-
-
0031019987
-
A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction
-
GRUNEWALD, S. M., S. KUNZMANN, B. SCHNARR, J. EZERNIEKS, W. SEBALD, and A. DUSCHL. 1997. A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction. J Biol Chem 272: 1480.
-
(1997)
J Biol Chem
, vol.272
, pp. 1480
-
-
Grunewald, S.M.1
Kunzmann, S.2
Schnarr, B.3
Ezernieks, J.4
Sebald, W.5
Duschl, A.6
-
41
-
-
0032482979
-
An immune cell-selective interleukin 4 agonist
-
SHANAFELT, A. B., C. P. FORTE, J. J. KASPER, L. SANCHEZ-PESCADOR, M. WETZEL, R. GUNDEL, and J. M. GREVE. 1998. An immune cell-selective interleukin 4 agonist. Proc Natl Acad Sci U S A 95: 9454.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 9454
-
-
Shanafelt, A.B.1
Forte, C.P.2
Kasper, J.J.3
Sanchez-Pescador, L.4
Wetzel, M.5
Gundel, R.6
Greve, J.M.7
-
42
-
-
0032193216
-
Specific antagonism of type I IL-4 receptor with a mutated form of murine IL-4
-
SCHNARE, M., H. BLUM, S. JUTTNER, M. ROLLINGHOFF, and A. GESSNER. 1998. Specific antagonism of type I IL-4 receptor with a mutated form of murine IL-4. J Immunol 161: 3484.
-
(1998)
J Immunol
, vol.161
, pp. 3484
-
-
Schnare, M.1
Blum, H.2
Juttner, S.3
Rollinghoff, M.4
Gessner, A.5
-
43
-
-
0031722677
-
Interleukin-4 receptor signalling mechanisms and their biological significance
-
NKELMS, K., H. HUANG, J. RYAN, A. KEEGAN, and W. E. PAUL. 1998. Interleukin-4 receptor signalling mechanisms and their biological significance. Adv Exp Med Biol 452: 37.
-
(1998)
Adv Exp Med Biol
, vol.452
, pp. 37
-
-
Nkelms, K.1
Huang, H.2
Ryan, J.3
Keegan, A.4
Paul, W.E.5
-
44
-
-
0032009864
-
Structure of and signal transduction through interleukin-4 and interleukin-13 receptors
-
MURATA, T., N. I. OBIRI, and R. K. PURI. 1998. Structure of and signal transduction through interleukin-4 and interleukin-13 receptors (review). Int J Mol Med 1: 551.
-
(1998)
Int J Mol Med
, vol.1
, pp. 551
-
-
Murata, T.1
Obiri, N.I.2
Puri, R.K.3
-
45
-
-
0032622175
-
Signal transduction via the interleukin-4 receptor and its correlation with atopy
-
IZUHARA, K., and T. SHIRAKAWA. 1999. Signal transduction via the interleukin-4 receptor and its correlation with atopy. Int J Mol Med 3: 3.
-
(1999)
Int J Mol Med
, vol.3
, pp. 3
-
-
Izuhara, K.1
Shirakawa, T.2
-
46
-
-
0033010373
-
The IL-4 receptor: Signaling mechanisms and biologic functions
-
NELMS, K., A. D. KEEGAN, J. ZAMORANO, J. J. RYAN, and W. E. PAUL. 1999. The IL-4 receptor: signaling mechanisms and biologic functions [In Process Citation]. Annu Rev Immunol 17: 701.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 701
-
-
Nelms, K.1
Keegan, A.D.2
Zamorano, J.3
Ryan, J.J.4
Paul, W.E.5
-
47
-
-
0030584699
-
IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: Similarities between IL-4 and IL-13 signaling
-
MURATA, T., P. D. NOGUCHI, and R. K. PURI. 1996. IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. J Immunol 156: 2972.
-
(1996)
J Immunol
, vol.156
, pp. 2972
-
-
Murata, T.1
Noguchi, P.D.2
Puri, R.K.3
-
48
-
-
0028935070
-
Distinct sequence motifs within the cytoplasmic domain of the human IL-4 receptor differentially regulate apoptosis inhibition and cell growth
-
DEUTSCH, H. H., K. KOETTNITZ, J. CHUNG, and F. S. KALTHOFF. 1995. Distinct sequence motifs within the cytoplasmic domain of the human IL-4 receptor differentially regulate apoptosis inhibition and cell growth. J Immunol 154: 3696.
-
(1995)
J Immunol
, vol.154
, pp. 3696
-
-
Deutsch, H.H.1
Koettnitz, K.2
Chung, J.3
Kalthoff, F.S.4
-
49
-
-
0001606677
-
Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules
-
CHEN, X. H., B. K. PATEL, L. M. WANG, M. FRANKEL, N. ELLMORE, R. A. FLAVELL, W. J. LAROCHELLE, and J. H. PIERCE. 1997. Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules. J Biol Chem 272: 6556.
-
(1997)
J Biol Chem
, vol.272
, pp. 6556
-
-
Chen, X.H.1
Patel, B.K.2
Wang, L.M.3
Frankel, M.4
Ellmore, N.5
Flavell, R.A.6
Larochelle, W.J.7
Pierce, J.H.8
-
50
-
-
0031068016
-
The IL-4-induced tyrosine phosphorylation of the insulin receptor substrate is dependent on JAK1 expression in human fibrosarcoma cells
-
WANG, H. Y., J. ZAMORANO, J. L. YOERKIE, W. E. PAUL, and A. D. KEEGAN. 1997. The IL-4-induced tyrosine phosphorylation of the insulin receptor substrate is dependent on JAK1 expression in human fibrosarcoma cells. J Immunol 158: 1037.
-
(1997)
J Immunol
, vol.158
, pp. 1037
-
-
Wang, H.Y.1
Zamorano, J.2
Yoerkie, J.L.3
Paul, W.E.4
Keegan, A.D.5
-
51
-
-
0028149328
-
JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes
-
YIN, T., M. L. TSANG, and Y. C. YANG. 1994. JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes. J Biol Chem 269: 26614.
-
(1994)
J Biol Chem
, vol.269
, pp. 26614
-
-
Yin, T.1
Tsang, M.L.2
Yang, Y.C.3
-
52
-
-
14444268978
-
Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway
-
Miyazaki, T., Takaoka, A., Nogueira, L., Dikic, I., Fujii, H., Tsujino, S., Mitani, Y., Maeda, M., Schlessinger, J., and Taniguchi, T. 1998. Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway. Genes Dev 12: 770.
-
(1998)
Genes Dev
, vol.12
, pp. 770
-
-
Miyazaki, T.1
Takaoka, A.2
Nogueira, L.3
Dikic, I.4
Fujii, H.5
Tsujino, S.6
Mitani, Y.7
Maeda, M.8
Schlessinger, J.9
Taniguchi, T.10
-
53
-
-
0029096408
-
Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases
-
YIN, T., S. R. KELLER, F. W. QUELLE, B. A. WITTHUHN, M. L. TSANG, G. E. LIENHARD, J. N. IHLE, and Y. C. YANG. 1995. Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases. J Biol Chem 270: 20497.
-
(1995)
J Biol Chem
, vol.270
, pp. 20497
-
-
Yin, T.1
Keller, S.R.2
Quelle, F.W.3
Witthuhn, B.A.4
Tsang, M.L.5
Lienhard, G.E.6
Ihle, J.N.7
Yang, Y.C.8
-
54
-
-
0030497506
-
Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways
-
OAKES, S. A., F. CANDOTTI, J. A. JOHNSTON, Y. Q. CHEN, J. J. RYAN, N. TAYLOR, X. LIU, L. HENNIGHAUSEN, L. D. NOTARANGELO, W. E. PAUL, R. M. BLAESE, and J. J. O'SHEA. 1996. Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways. Immunity 5: 605.
-
(1996)
Immunity
, vol.5
, pp. 605
-
-
Oakes, S.A.1
Candotti, F.2
Johnston, J.A.3
Chen, Y.Q.4
Ryan, J.J.5
Taylor, N.6
Liu, X.7
Hennighausen, L.8
Notarangelo, L.D.9
Paul, W.E.10
Blaese, R.M.11
O'Shea, J.J.12
-
55
-
-
0030915682
-
Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain
-
FUJIWARA, H., S. H. HANISSIAN, A. TSYTSYKOVA, and R. S. GEHA. 1997. Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain. Proc Natl Acad Sci U S A 94: 5866.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 5866
-
-
Fujiwara, H.1
Hanissian, S.H.2
Tsytsykova, A.3
Geha, R.S.4
-
56
-
-
15444343191
-
Mouse macrophage development in the absence of the common gamma chain: Defining receptor complexes responsible for IL-4 and IL-13 signaling
-
ANDERSSON, A., S. M. GRUNEWALD, A. DUSCHL, A. FISCHER, and J. P. DISANTO. 1997. Mouse macrophage development in the absence of the common gamma chain: defining receptor complexes responsible for IL-4 and IL-13 signaling. Eur J Immunol 27: 1762.
-
(1997)
Eur J Immunol
, vol.27
, pp. 1762
-
-
Andersson, A.1
Grunewald, S.M.2
Duschl, A.3
Fischer, A.4
Disanto, J.P.5
-
57
-
-
0032525073
-
Interleukin-13 receptor alpha' but not alpha chain: A functional component of interleukin-4 receptors
-
MURATA, T., J. TAGUCHI, and R. K. PURI. 1998. Interleukin-13 receptor alpha' but not alpha chain: a functional component of interleukin-4 receptors. Blood 91: 3884.
-
(1998)
Blood
, vol.91
, pp. 3884
-
-
Murata, T.1
Taguchi, J.2
Puri, R.K.3
-
58
-
-
0032529410
-
Characterization of a mobile Stat6 activation motif in the human IL-4 receptor
-
RYAN, J. J., L. J. MCREYNOLDS, H. HUANG, K. NELMS, and W. E. PAUL. 1998. Characterization of a mobile Stat6 activation motif in the human IL-4 receptor. J Immunol 161: 1811.
-
(1998)
J Immunol
, vol.161
, pp. 1811
-
-
Ryan, J.J.1
McReynolds, L.J.2
Huang, H.3
Nelms, K.4
Paul, W.E.5
-
59
-
-
0029062423
-
The rat interleukin 4 receptor: Coevolution of ligand and receptor
-
RICHTER, G., G. HEIN, T. BLANKENSTEIN, and T. DIAMANTSTEIN. 1995. The rat interleukin 4 receptor: coevolution of ligand and receptor. Cytokine 7: 237.
-
(1995)
Cytokine
, vol.7
, pp. 237
-
-
Richter, G.1
Hein, G.2
Blankenstein, T.3
Diamantstein, T.4
-
60
-
-
0027972046
-
An interleukin-4-induced transcription factor: IL-4 Stat
-
HOU, J., U. SCHINDLER, W. J. HENZEL, T. C. HO, M. BRASSEUR, and S. L. MCKNIGHT. 1994. An interleukin-4-induced transcription factor: IL-4 Stat. Science 265: 1701.
-
(1994)
Science
, vol.265
, pp. 1701
-
-
Hou, J.1
Schindler, U.2
Henzel, W.J.3
Ho, T.C.4
Brasseur, M.5
McKnight, S.L.6
-
61
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
TAKEDA, K., T TANAKA., W SHI., M. MATSUMOTO, M. MINAMI, S. KASHIWAMURA, K. NAKANISHI, N. YOSHIDA, T. KISHIMOTO, and S. AKIRA. 1996. Essential role of Stat6 in IL-4 signalling. Nature 380: 627.
-
(1996)
Nature
, vol.380
, pp. 627
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
Matsumoto, M.4
Minami, M.5
Kashiwamura, S.6
Nakanishi, K.7
Yoshida, N.8
Kishimoto, T.9
Akira, S.10
-
62
-
-
0032007351
-
IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis
-
URBAN, J. F., JR., N. NOBEN-TRAUTH, D. D. DONALDSON, K. B. MADDEN, S. C MORRIS., M. COLLINS, and F. D. FINKELMAN. 1998. IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 8: 255.
-
(1998)
Immunity
, vol.8
, pp. 255
-
-
Urban J.F., Jr.1
Noben-Trauth, N.2
Donaldson, D.D.3
Madden, K.B.4
Morris, S.C.5
Collins, M.6
Finkelman, F.D.7
-
63
-
-
0032519993
-
Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response
-
KAPLAN, M. H., J. R. WHITFIELD, D. L. BOROS, and M. J. GRUSBY. 1998. Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response. J Immunol 160: 1850.
-
(1998)
J Immunol
, vol.160
, pp. 1850
-
-
Kaplan, M.H.1
Whitfield, J.R.2
Boros, D.L.3
Grusby, M.J.4
-
64
-
-
0033566955
-
BCL-6-Deficient mice reveal an IL-4-independent, STAT6-dependent pathway that controls susceptibility to infection by leishmania major
-
DENT, A. L., T. M. DOHERTY, W. E. PAUL, A. SHER, and L. M. STAUDT. 1999. BCL-6-Deficient mice reveal an IL-4-independent, STAT6-dependent pathway that controls susceptibility to infection by leishmania major [In Process Citation]. J Immunol 163: 2098.
-
(1999)
J Immunol
, vol.163
, pp. 2098
-
-
Dent, A.L.1
Doherty, T.M.2
Paul, W.E.3
Sher, A.4
Staudt, L.M.5
-
65
-
-
0032403565
-
Mice with STAT6-targeted gene disruption develop a Th1 response and control cutaneous leishmaniasis
-
STAMM, L. M., A. RAISANEN-SOKOLOWSKI, M. OKANO, M. E. RUSSELL, J. R. DAVID, and A. R. SATOSKAR. 1998. Mice with STAT6-targeted gene disruption develop a Th1 response and control cutaneous leishmaniasis. J Immunol 161: 6180.
-
(1998)
J Immunol
, vol.161
, pp. 6180
-
-
Stamm, L.M.1
Raisanen-Sokolowski, A.2
Okano, M.3
Russell, M.E.4
David, J.R.5
Satoskar, A.R.6
-
66
-
-
0032536837
-
Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
-
KUPERMAN, D., B. SCHOFIELD, M. WILLS-KARP, and M. J. GRUSBY. 1998. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J Exp Med 187: 939.
-
(1998)
J Exp Med
, vol.187
, pp. 939
-
-
Kuperman, D.1
Schofield, B.2
Wills-Karp, M.3
Grusby, M.J.4
-
67
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
SHIMODA, K., J. VAN DEURSEN, M. Y. SANGSTER, S. R. SARAWAR, R. T. CARSON, R. A. TRIPP, C. CHU, F. W. QUELLE, T. NOSAKA, D. A. VIGNALI, P. C DOHERTY., G. GROSVELD, W. E. PAUL, and J. N. IHLE. 1996. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 380: 630.
-
(1996)
Nature
, vol.380
, pp. 630
-
-
Shimoda, K.1
Van Deursen, J.2
Sangster, M.Y.3
Sarawar, S.R.4
Carson, R.T.5
Tripp, R.A.6
Chu, C.7
Quelle, F.W.8
Nosaka, T.9
Vignali, D.A.10
Doherty, P.C.11
Grosveld, G.12
Paul, W.E.13
Ihle, J.N.14
-
68
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
KAPLAN, M. H., U. SCHINDLER, S. T. SMILEY, and M. J. GRUSBY. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4: 313.
-
(1996)
Immunity
, vol.4
, pp. 313
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
69
-
-
0031859134
-
STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination
-
LINEHAN, L. A., W. D. WARREN, P. A. THOMPSON, M. J. GRUSBY, and M. T. BERTON. 1998. STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination. J. Immunol. 161: 302.
-
(1998)
J. Immunol.
, vol.161
, pp. 302
-
-
Linehan, L.A.1
Warren, W.D.2
Thompson, P.A.3
Grusby, M.J.4
Berton, M.T.5
-
70
-
-
0029795585
-
Interleukin-4-induced STAT6 recognizes and activates a target site in the promoter of the interleukin-4 receptor gene
-
KOTANIDES, H., and N. C. REICH. 1996. Interleukin-4-induced STAT6 recognizes and activates a target site in the promoter of the interleukin-4 receptor gene. J Biol Chem 271: 25555.
-
(1996)
J Biol Chem
, vol.271
, pp. 25555
-
-
Kotanides, H.1
Reich, N.C.2
-
71
-
-
0031913911
-
Regulation of interleukin 4-mediated signaling by naturally occurring dominant negative and attenuated forms of human Stat6
-
PATEL, B. K. R., J. H. PIERCE, and W. J. LAROCHELLE. 1998. Regulation of interleukin 4-mediated signaling by naturally occurring dominant negative and attenuated forms of human Stat6. Proc. Natl. Acad. Sci. U S A 95: 172.
-
(1998)
Proc. Natl. Acad. Sci. U S A
, vol.95
, pp. 172
-
-
Patel, B.K.R.1
Pierce, J.H.2
Larochelle, W.J.3
-
72
-
-
0030576990
-
IL4 and IL13 receptors share the gamma c chain and activate STAT6, STAT3 and STAT5 proteins in normal human B cells
-
ROLLING, C., D. TRETON, S. PELLEGRINI, P. GALANAUD, and Y. RICHARD. 1996. IL4 and IL13 receptors share the gamma c chain and activate STAT6, STAT3 and STAT5 proteins in normal human B cells. FEBS Lett 393: 53.
-
(1996)
FEBS Lett
, vol.393
, pp. 53
-
-
Rolling, C.1
Treton, D.2
Pellegrini, S.3
Galanaud, P.4
Richard, Y.5
-
73
-
-
0032799029
-
Activation of STATS by IL-4 relies on Janus kinase function but not on receptor tyrosinc phosphorylation, and can contribute to both cell proliferation and gene regulation
-
FRIEDRICH, K., W. KAMMER, I. ERHARDT, S. BR#NDLEIN, W. SEBALD, and R. MORIGGL. 1999. Activation of STATS by IL-4 relies on Janus kinase function but not on receptor tyrosinc phosphorylation, and can contribute to both cell proliferation and gene regulation. Int Immunol 11: 1283.
-
(1999)
Int Immunol
, vol.11
, pp. 1283
-
-
Friedrich, K.1
Kammer, W.2
Erhardt, I.3
Brndlein, S.4
Sebald, W.5
Moriggl, R.6
-
74
-
-
0033083261
-
IL-4 selectively inhibits IL-2-triggered StatS activation, but not proliferation, in human T cells
-
CASTRO, A., T. K. SENGUPTA, D. C. RUIZ, E. YANG, and L. B. IVASHKIV. 1999. IL-4 selectively inhibits IL-2-triggered StatS activation, but not proliferation, in human T cells. J Immunol 162: 1261.
-
(1999)
J Immunol
, vol.162
, pp. 1261
-
-
Castro, A.1
Sengupta, T.K.2
Ruiz, D.C.3
Yang, E.4
Ivashkiv, L.B.5
-
75
-
-
0028219966
-
An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-I phosphorylation and cell growth
-
KEEGAN, A. D., K. NELMS, M. WHITE, L. M. WANG, J. H. PIERCE, and W. E. PAUL. 1994. An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-I phosphorylation and cell growth. Cell 76: 811.
-
(1994)
Cell
, vol.76
, pp. 811
-
-
Keegan, A.D.1
Nelms, K.2
White, M.3
Wang, L.M.4
Pierce, J.H.5
Paul, W.E.6
-
76
-
-
0029148591
-
Role of IRS-2 in insulin and cytokine signalling
-
SUN, X. J., L. M. WANG, Y. ZHANG, L. YENUSH, M. G. MYERS, JR., E. GLASHEEN, W. S. LANE, J. H. PIERCE, and M. F. WHITE. 1995. Role of IRS-2 in insulin and cytokine signalling. Nature 377: 173.
-
(1995)
Nature
, vol.377
, pp. 173
-
-
Sun, X.J.1
Wang, L.M.2
Zhang, Y.3
Yenush, L.4
Myers M.G., Jr.5
Glasheen, E.6
Lane, W.S.7
Pierce, J.H.8
White, M.F.9
-
77
-
-
0028876283
-
Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases
-
JOHNSTON, J. A., L. M. WANG, E. P. HANSON, X. J. SUN, M. F WHITE., S. A. OAKES, J. H. PIERCE, and J. J. O'SHEA. 1995. Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases. J Biol Chem 270: 28527.
-
(1995)
J Biol Chem
, vol.270
, pp. 28527
-
-
Johnston, J.A.1
Wang, L.M.2
Hanson, E.P.3
Sun, X.J.4
White, M.F.5
Oakes, S.A.6
Pierce, J.H.7
O'Shea, J.J.8
-
78
-
-
0031012544
-
Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells
-
WELHAM, M. J., H. BONE, M. LEVINGS, L. LEARMONTH, L. M. WANG, K. B. LESLIE, J. H. PIERCE, and J. W. SCHRADER. 1997. Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells. J Biol Chem 272: 1377.
-
(1997)
J Biol Chem
, vol.272
, pp. 1377
-
-
Welham, M.J.1
Bone, H.2
Levings, M.3
Learmonth, L.4
Wang, L.M.5
Leslie, K.B.6
Pierce, J.H.7
Schrader, J.W.8
-
79
-
-
0030848782
-
A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family
-
LAVAN, B. E., V. R. FANTIN, E. T. CHANG, W. S. LANE, S. R. KELLER, and G. E. LIENHARD. 1997. A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family. J Biol Chem 272: 21403.
-
(1997)
J Biol Chem
, vol.272
, pp. 21403
-
-
Lavan, B.E.1
Fantin, V.R.2
Chang, E.T.3
Lane, W.S.4
Keller, S.R.5
Lienhard, G.E.6
-
80
-
-
0030995946
-
The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family
-
LAVAN, B. E., W. S. LANE, and G. E. LIENHARD. 1997. The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family. J Biol Chem 272: 11439.
-
(1997)
J Biol Chem
, vol.272
, pp. 11439
-
-
Lavan, B.E.1
Lane, W.S.2
Lienhard, G.E.3
-
81
-
-
0028874953
-
PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities
-
WOLF, G., T. TRUB, E. OTTINGER, L. GRONINGA, A. LYNCH, M. F. WHITE, M. MIYAZAKI, J. LEE, and S. E. SHOELSON. 1995. PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities. J Biol Chem 270: 27407.
-
(1995)
J Biol Chem
, vol.270
, pp. 27407
-
-
Wolf, G.1
Trub, T.2
Ottinger, E.3
Groninga, L.4
Lynch, A.5
White, M.F.6
Miyazaki, M.7
Lee, J.8
Shoelson, S.E.9
-
82
-
-
0029940882
-
Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain
-
ZHOU, M. M., B. HUANG, E. T. OLEJNICZAK, R. P. MEADOWS, S. B. SHUKER, M. MIYAZAKI, T. TRUB, S. E. SHOELSON, and S. W. FESIK. 1996. Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain. Nat Struct Biol 3: 388.
-
(1996)
Nat Struct Biol
, vol.3
, pp. 388
-
-
Zhou, M.M.1
Huang, B.2
Olejniczak, E.T.3
Meadows, R.P.4
Shuker, S.B.5
Miyazaki, M.6
Trub, T.7
Shoelson, S.E.8
Fesik, S.W.9
-
83
-
-
0027992342
-
Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins
-
GOLD, M. R., V. DURONIO, S. P. SAXENA, J. W. SCHRADER, and R. AEBERSOLD. 1994. Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins. J Biol Chem 269: 5403.
-
(1994)
J Biol Chem
, vol.269
, pp. 5403
-
-
Gold, M.R.1
Duronio, V.2
Saxena, S.P.3
Schrader, J.W.4
Aebersold, R.5
-
84
-
-
0029972883
-
Evidence for a role of phosphatidylinositol 3-kinase in IL-4-induced germline C epsilon transcription
-
IKIZAWA, K., K. KAJIWARA, Y BASAKI., T. KOSHIO, and Y. YANAGIHARA. 1996. Evidence for a role of phosphatidylinositol 3-kinase in IL-4-induced germline C epsilon transcription. Cell Immunol 170: 134.
-
(1996)
Cell Immunol
, vol.170
, pp. 134
-
-
Ikizawa, K.1
Kajiwara, K.2
Basaki, Y.3
Koshio, T.4
Yanagihara, Y.5
-
85
-
-
0030582693
-
Interleukin-4 activates two distinct pathways of phosphatidylinositol-3 kinase in the same cells
-
IZUHARA, K., and N. HARADA. 1996. Interleukin-4 activates two distinct pathways of phosphatidylinositol-3 kinase in the same cells. Biochem Biophys Res Commun 229: 624.
-
(1996)
Biochem Biophys Res Commun
, vol.229
, pp. 624
-
-
Izuhara, K.1
Harada, N.2
-
86
-
-
0029849027
-
Interleukin-4 induces association of the c-fes proto-oncogene product with phosphatidylinositol-3 kinase
-
IZUHARA, K., R. A. FELDMAN, P. GREER, and N. HARADA. 1996. Interleukin-4 induces association of the c-fes proto-oncogene product with phosphatidylinositol-3 kinase. Blood 88: 3910.
-
(1996)
Blood
, vol.88
, pp. 3910
-
-
Izuhara, K.1
Feldman, R.A.2
Greer, P.3
Harada, N.4
-
87
-
-
0028225367
-
Interaction of the c-fes proto-oncogene product with the interleukin-4 receptor
-
IZUHARA, K., R. A. FELDMAN, P. GREER, P., and N. HARADA. 1994. Interaction of the c-fes proto-oncogene product with the interleukin-4 receptor. J Biol Chem 269: 18623.
-
(1994)
J Biol Chem
, vol.269
, pp. 18623
-
-
Izuhara, K.1
Feldman, R.A.2
Greer, P.3
Harada, N.4
-
88
-
-
0033561763
-
Phosphatidylinositol 3′-kinase, but not S6-kinase, is required for insulin-like growth factor-I and IL-4 to maintain expression of Bcl-2 and promote survival of myeloid progenitors
-
MINSHALL, C., S. ARKINS, R. DANTZER, G. G. FREUND, and K. W. KELLEY. 1999. Phosphatidylinositol 3′-kinase, but not S6-kinase, is required for insulin-like growth factor-I and IL-4 to maintain expression of Bcl-2 and promote survival of myeloid progenitors. J Immunol 162: 4542.
-
(1999)
J Immunol
, vol.162
, pp. 4542
-
-
Minshall, C.1
Arkins, S.2
Dantzer, R.3
Freund, G.G.4
Kelley, K.W.5
-
89
-
-
0031964845
-
c-Cbl is tyrosine-phosphorylated by interleukin-4 and enhances mitogenic and survival signals of interleukin-4 receptor by linking with the phosphatidylinositol 3′-kinase pathway
-
UENO, H., K. SASAKI, H. HONDA, T. NAKAMOTO, T. YAMAGATA, K. MIYAGAWA, K., MITANI, Y. YAZAKI, and H. HIRAI. 1998. c-Cbl is tyrosine-phosphorylated by interleukin-4 and enhances mitogenic and survival signals of interleukin-4 receptor by linking with the phosphatidylinositol 3′-kinase pathway. Blood 91: 46.
-
(1998)
Blood
, vol.91
, pp. 46
-
-
Ueno, H.1
Sasaki, K.2
Honda, H.3
Nakamoto, T.4
Yamagata, T.5
Miyagawa, K.6
Mitani, K.7
Yazaki, Y.8
Hirai, H.9
-
90
-
-
0028068607
-
Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′-kinase
-
WELHAM, M. J., U. DECHERT, K. B. LESLIE, F. JIRIK, and J. W. SCHRADER. 1994. Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′-kinase. J Biol Chem 269: 23764.
-
(1994)
J Biol Chem
, vol.269
, pp. 23764
-
-
Welham, M.J.1
Dechert, U.2
Leslie, K.B.3
Jirik, F.4
Schrader, J.W.5
-
91
-
-
0031013368
-
Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway
-
FOLTZ, I. N., J. C. LEE, P. R. YOUNG, and J. W. SCHRADER. 1997. Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway. J Biol Chem 272: 3296.
-
(1997)
J Biol Chem
, vol.272
, pp. 3296
-
-
Foltz, I.N.1
Lee, J.C.2
Young, P.R.3
Schrader, J.W.4
-
92
-
-
0032055541
-
Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper 2-derived cytokines interleukin-4 and interleukin-5
-
COFFER, P. J., R. C. SCHWEIZER, G. R. DUBOIS, T. MAIKOE, J. W. LAMMERS, and L. KOENDERMAN. 1998. Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper 2-derived cytokines interleukin-4 and interleukin-5. Blood 91: 2547.
-
(1998)
Blood
, vol.91
, pp. 2547
-
-
Coffer, P.J.1
Schweizer, R.C.2
Dubois, G.R.3
Maikoe, T.4
Lammers, J.W.5
Koenderman, L.6
-
93
-
-
0033605124
-
CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. A target of interleukin (il)-4 and il-10 anti-inflammatory action
-
SUTTLES, J., D. M. MILHORN, R. W. MILLER, J. C. POE, L. M. WAHL, and R. D. STOUT. 1999. CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. A target of interleukin (il)-4 and il-10 anti-inflammatory action. J Biol Chem 274: 5835.
-
(1999)
J Biol Chem
, vol.274
, pp. 5835
-
-
Suttles, J.1
Milhorn, D.M.2
Miller, R.W.3
Poe, J.C.4
Wahl, L.M.5
Stout, R.D.6
-
94
-
-
0032544403
-
MAP kinase pathways as a route for regulatory mechanisms of IL-10 and IL-4 which inhibit COX-2 expression in human monocytes
-
NIIRO, H., T OTSUKA., E. OGAMI, K. YAMAOKA, S. NAGANO, M. AKAHOSHI, H. NAKASHIMA, Y. ARINOBU, K. IZUHARA, and Y. NIHO. 1998. MAP kinase pathways as a route for regulatory mechanisms of IL-10 and IL-4 which inhibit COX-2 expression in human monocytes. Biochem Biophys Res Commun 250: 200.
-
(1998)
Biochem Biophys Res Commun
, vol.250
, pp. 200
-
-
Niiro, H.1
Otsuka, T.2
Ogami, E.3
Yamaoka, K.4
Nagano, S.5
Akahoshi, M.6
Nakashima, H.7
Arinobu, Y.8
Izuhara, K.9
Niho, Y.10
-
95
-
-
0032400931
-
Inhibitors of the p38 mitogen-activated kinase modulate IL-4 induction of low affinity IgE receptor (CD23) in human monocytes
-
MARSHALL, L. A., M. J. HANSBURY, B. J. BOLOGNESE, R. J. GUM, P. R. YOUNG, and R. J. MAYER. 1998. Inhibitors of the p38 mitogen-activated kinase modulate IL-4 induction of low affinity IgE receptor (CD23) in human monocytes. J Immunol 161: 6005.
-
(1998)
J Immunol
, vol.161
, pp. 6005
-
-
Marshall, L.A.1
Hansbury, M.J.2
Bolognese, B.J.3
Gum, R.J.4
Young, P.R.5
Mayer, R.J.6
-
96
-
-
0030012322
-
Interleukin-4 induces activation of mitogen-activated protein kinase and phosphorylation of shc in human keratinocytes
-
WERY, S., M. LETOURNEUR, J. BERTOGLIO, and J. PIERRE. 1996. Interleukin-4 induces activation of mitogen-activated protein kinase and phosphorylation of shc in human keratinocytes. J Biol Chem 271: 8529.
-
(1996)
J Biol Chem
, vol.271
, pp. 8529
-
-
Wery, S.1
Letourneur, M.2
Bertoglio, J.3
Pierre, J.4
-
97
-
-
0032545279
-
Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4-and IL-13-dependent signal transduction
-
HAQUE, S. J., P. HARBOR, M. TABRIZI, T. YI, and B. R. WILLIAMS. 1998. Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4-and IL-13-dependent signal transduction. J Biol Chem 273: 33893.
-
(1998)
J Biol Chem
, vol.273
, pp. 33893
-
-
Haque, S.J.1
Harbor, P.2
Tabrizi, M.3
Yi, T.4
Williams, B.R.5
-
98
-
-
0030962582
-
Interleukin-4 (IL-4) induces phosphatidylinositol 3-kinase (p85) dephosphorylation. Implications for the role of SHP-1 in the IL-4-induced signals in human B cells
-
IMANI, F., B. RAGERX, B. CATIPOVIC, and D. G. MARSH. 1997. Interleukin-4 (IL-4) induces phosphatidylinositol 3-kinase (p85) dephosphorylation. Implications for the role of SHP-1 in the IL-4-induced signals in human B cells. J Biol Chem 272: 7927.
-
(1997)
J Biol Chem
, vol.272
, pp. 7927
-
-
Imani, F.1
Ragerx, B.2
Catipovic, B.3
Marsh, D.G.4
-
99
-
-
0027158159
-
The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp
-
KUHNE, M. R., T. PAWSON, G. E. LIENHARD, and G. S. FENG. 1993. The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp. J Biol Chem 268: 11479.
-
(1993)
J Biol Chem
, vol.268
, pp. 11479
-
-
Kuhne, M.R.1
Pawson, T.2
Lienhard, G.E.3
Feng, G.S.4
-
100
-
-
0032523416
-
Involvement of SHP-2 in multiple aspects of IL-2 signaling: Evidence for a positive regulatory role
-
GADINA, M., L. M. STANCATO, C. M. BACON, A. C. LARNER, and J. J. O'SHEA. 1998. Involvement of SHP-2 in multiple aspects of IL-2 signaling: evidence for a positive regulatory role. J Immunol 160: 4657.
-
(1998)
J Immunol
, vol.160
, pp. 4657
-
-
Gadina, M.1
Stancato, L.M.2
Bacon, C.M.3
Larner, A.C.4
O'Shea, J.J.5
-
101
-
-
0032528425
-
Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis
-
ZAMORANO, J., and A. D. KEEGAN. 1998. Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. J Immunol 161: 859.
-
(1998)
J Immunol
, vol.161
, pp. 859
-
-
Zamorano, J.1
Keegan, A.D.2
-
102
-
-
0032126362
-
FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation
-
NELMS, K., A. L. SNOW, J. HU-LI, and W. E. PAUL. 1998. FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation. Immunity 9: 13.
-
(1998)
Immunity
, vol.9
, pp. 13
-
-
Nelms, K.1
Snow, A.L.2
Hu-Li, J.3
Paul, W.E.4
-
103
-
-
0031800490
-
The SOCS proteins: A new family of negative regulators of signal transduction
-
NICHOLSON, S. E., and D. J. HILTON. 1998. The SOCS proteins: a new family of negative regulators of signal transduction. J Leukoc Biol 63: 665.
-
(1998)
J Leukoc Biol
, vol.63
, pp. 665
-
-
Nicholson, S.E.1
Hilton, D.J.2
-
104
-
-
0033120880
-
Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction
-
LOSMAN, J. A., X. P. CHEN, D. HILTON, and P. ROTHMAN. 1999. Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction. J Immunol 162: 3770.
-
(1999)
J Immunol
, vol.162
, pp. 3770
-
-
Losman, J.A.1
Chen, X.P.2
Hilton, D.3
Rothman, P.4
-
105
-
-
0030931043
-
An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice
-
NOBEN-TRAUTH, N., L. D. SHULTZ, F. BROMBACHER, J. F. URBAN, JR., H. GU, and W. E. PAUL. 1997. An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice. Proc Natl Acad Sci U S A 94: 10838.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10838
-
-
Noben-Trauth, N.1
Shultz, L.D.2
Brombacher, F.3
Urban J.F., Jr.4
Gu, H.5
Paul, W.E.6
-
106
-
-
0033564686
-
Differences between IL-4-and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling
-
Mohrs, M., Ledermann, B., Kohler, G., Dorfmuller, A., Gessner, A., and Brombacher, F. 1999. Differences between IL-4-and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling. J Immunol 162: 7302.
-
(1999)
J Immunol
, vol.162
, pp. 7302
-
-
Mohrs, M.1
Ledermann, B.2
Kohler, G.3
Dorfmuller, A.4
Gessner, A.5
Brombacher, F.6
-
107
-
-
0033563135
-
IL-4-and IL-4 receptor-deficient BALB/c mice reveal differences in susceptibility to Leishmania major parasite substrains
-
NOBEN-TRAUTH, N., W. E. PAUL, and D. L. SACKS. 1999. IL-4-and IL-4 receptor-deficient BALB/c mice reveal differences in susceptibility to Leishmania major parasite substrains. J Immunol 162: 6132.
-
(1999)
J Immunol
, vol.162
, pp. 6132
-
-
Noben-Trauth, N.1
Paul, W.E.2
Sacks, D.L.3
-
108
-
-
0033562979
-
Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils
-
COHN, L., R. J. HOMER, H. MACLEOD, M. MOHRS, F. BROMBACHER, and K. BOTTOMLY, 1999. Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils. J Immunol 162: 6178.
-
(1999)
J Immunol
, vol.162
, pp. 6178
-
-
Cohn, L.1
Homer, R.J.2
Macleod, H.3
Mohrs, M.4
Brombacher, F.5
Bottomly, K.6
-
109
-
-
0033168893
-
Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile
-
JANKOVIC, D., M. C. KULLBERG, N. NOBEN-TRAUTH, P. CASPAR, J. M. WARD, A. W. CHEEVER, W. E. PAUL, and A. SHER. 1999. Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile. J Immunol 163: 337.
-
(1999)
J Immunol
, vol.163
, pp. 337
-
-
Jankovic, D.1
Kullberg, M.C.2
Noben-Trauth, N.3
Caspar, P.4
Ward, J.M.5
Cheever, A.W.6
Paul, W.E.7
Sher, A.8
-
110
-
-
0028226196
-
Soluble receptors for cytokines and growth factors: Generation and biological function
-
ROSE-JOHN, S., and P. C. HEINRICH. 1994. Soluble receptors for cytokines and growth factors: generation and biological function. Biochem J 300: 281.
-
(1994)
Biochem J
, vol.300
, pp. 281
-
-
Rose-John, S.1
Heinrich, P.C.2
-
111
-
-
0029834318
-
Soluble cytokine receptors: Their roles in immunoregulation, disease, and therapy
-
FERNANDEZ-BOTRAN, R., P. M. CHILTON, and Y. MA. 1996. Soluble cytokine receptors: their roles in immunoregulation, disease, and therapy. Adv Immunol 63: 269.
-
(1996)
Adv Immunol
, vol.63
, pp. 269
-
-
Fernandez-Botran, R.1
Chilton, P.M.2
Ma, Y.3
-
112
-
-
0031879125
-
Soluble receptors in human disease
-
HEANEY, M. L., and D. W. GOLDE. 1998. Soluble receptors in human disease. J Leukoc Biol 64: 135.
-
(1998)
J Leukoc Biol
, vol.64
, pp. 135
-
-
Heaney, M.L.1
Golde, D.W.2
-
113
-
-
0025516598
-
A soluble form of the interleukin 4 receptor in biological fluids
-
FANSLOW, W. C., K. CLIFFORD, T VANDENBOS., A. TEEL, R. J. ARMITAGE, and M. P. BECKMANN. 1990. A soluble form of the interleukin 4 receptor in biological fluids. Cytokine 2: 398.
-
(1990)
Cytokine
, vol.2
, pp. 398
-
-
Fanslow, W.C.1
Clifford, K.2
Vandenbos, T.3
Teel, A.4
Armitage, R.J.5
Beckmann, M.P.6
-
114
-
-
0025362240
-
A soluble, high-affinity, interleukin-4-binding protein is present in the biological fluids of mice
-
FERNANDEZ-BOTRAN, R., and E. S. VITETTA. 1990. A soluble, high-affinity, interleukin-4-binding protein is present in the biological fluids of mice. Proc Natl Acad Sci U S A 87: 4202.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 4202
-
-
Fernandez-Botran, R.1
Vitetta, E.S.2
-
115
-
-
0033386439
-
Increased levels of soluble interleukin-4 receptor in the sera of patients with visceral leishmaniasis
-
SANG, D. K., J. H. OUMA, C. C. JOHN, C. C. WHALEN, C. L. KING, A. A. MAHMOUD, and F. P. HEINZEL. 1999. Increased levels of soluble interleukin-4 receptor in the sera of patients with visceral leishmaniasis. J Infect Dis 179: 743.
-
(1999)
J Infect Dis
, vol.179
, pp. 743
-
-
Sang, D.K.1
Ouma, J.H.2
John, C.C.3
Whalen, C.C.4
King, C.L.5
Mahmoud, A.A.6
Heinzel, F.P.7
-
116
-
-
0025762023
-
A recombinant extracellular domain of the human interleukin 4 receptor inhibits the biological effects of interleukin 4 on T and B lymphocytes
-
GARRONE, P., O. DJOSSOU, J. P GALIZZI., and J. Banchereau. 1991. A recombinant extracellular domain of the human interleukin 4 receptor inhibits the biological effects of interleukin 4 on T and B lymphocytes. Eur J Immunol 21: 1365.
-
(1991)
Eur J Immunol
, vol.21
, pp. 1365
-
-
Garrone, P.1
Djossou, O.2
Galizzi, J.P.3
Banchereau, J.4
-
117
-
-
0025272374
-
Cytokine receptors and B cell functions. I. Recombinant soluble receptors specifically inhibit IL-1-and IL-4-induced B cell activities in vitro
-
MALISZEWSKI, C. R., T. A. SATO, T. VANDEN BOS, S. WAUGH, S. K. DOWER, J. SLACK, M. P. BECKMANN, and K. H. GRABSTEIN. 1990. Cytokine receptors and B cell functions. I. Recombinant soluble receptors specifically inhibit IL-1-and IL-4-induced B cell activities in vitro. J Immunol 144: 3028.
-
(1990)
J Immunol
, vol.144
, pp. 3028
-
-
Maliszewski, C.R.1
Sato, T.A.2
Vanden Bos, T.3
Waugh, S.4
Dower, S.K.5
Slack, J.6
Beckmann, M.P.7
Grabstein, K.H.8
-
118
-
-
0025902284
-
Evidence that natural murine soluble interleukin 4 receptors may act as transport proteins
-
FERNANDEZ-BOTRAN, R., and E. S. VITETTA. 1991. Evidence that natural murine soluble interleukin 4 receptors may act as transport proteins. J Exp Med 174: 673.
-
(1991)
J Exp Med
, vol.174
, pp. 673
-
-
Fernandez-Botran, R.1
Vitetta, E.S.2
-
119
-
-
0025800070
-
Regulation of alloreactivity in vivo by IL-4 and the soluble IL-4 receptor
-
FANSLOW, W. C., K. N. CLIFFORD, L. S. PARK, A. S. RUBIN, R. F. VOICE, M. P. BECKMANN, and M. B. WIDMER. 1991. Regulation of alloreactivity in vivo by IL-4 and the soluble IL-4 receptor. J Immunol 147: 535.
-
(1991)
J Immunol
, vol.147
, pp. 535
-
-
Fanslow, W.C.1
Clifford, K.N.2
Park, L.S.3
Rubin, A.S.4
Voice, R.F.5
Beckmann, M.P.6
Widmer, M.B.7
-
120
-
-
0028836664
-
Inhibition of allergen-induced IgE and IgG1 production by soluble IL-4 receptor
-
RENZ, H., K. ENSSLE, L. LAUFFER, R. KURRLE, and E. W. GELFAND. 1995. Inhibition of allergen-induced IgE and IgG1 production by soluble IL-4 receptor. Int Arch Allergy Immunol 106: 46.
-
(1995)
Int Arch Allergy Immunol
, vol.106
, pp. 46
-
-
Renz, H.1
Enssle, K.2
Lauffer, L.3
Kurrle, R.4
Gelfand, E.W.5
-
121
-
-
0030040387
-
Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor
-
RENZ, H., K. BRADLEY, K. ENSSLE, J. E. LOADER, E. W. LARSENX, and E. W. GELFAND. 1996. Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor. Int Arch Allergy Immunol 109: 167.
-
(1996)
Int Arch Allergy Immunol
, vol.109
, pp. 167
-
-
Renz, H.1
Bradley, K.2
Enssle, K.3
Loader, J.E.4
Larsenx, E.W.5
Gelfand, E.W.6
-
122
-
-
0033564667
-
Therapeutic protective effects of IL-12 combined with soluble IL-4 receptor against established infections of herpes simplex virus type 1 in thermally injured mice
-
KOBAYASHI, H., M. KOBAYASHI, T. UTSUNOMIYA, D. N. HERNDON, R. B. POLLARD, and F. SUZUKI. 1999. Therapeutic protective effects of IL-12 combined with soluble IL-4 receptor against established infections of herpes simplex virus type 1 in thermally injured mice. J Immunol 162: 7148.
-
(1999)
J Immunol
, vol.162
, pp. 7148
-
-
Kobayashi, H.1
Kobayashi, M.2
Utsunomiya, T.3
Herndon, D.N.4
Pollard, R.B.5
Suzuki, F.6
-
123
-
-
0027263302
-
Recombinant soluble murine IL-4 receptor can inhibit or enhance IgE responses in vivo
-
SATO, T. A., M. B. WIDMER, F. D. FINKELMAN, H. MADANI, C. A. JACOBS, K. H. GRABSTEIN, and C. R. MALISZEWSKI. 1993. Recombinant soluble murine IL-4 receptor can inhibit or enhance IgE responses in vivo. J Immunol 150: 2717.
-
(1993)
J Immunol
, vol.150
, pp. 2717
-
-
Sato, T.A.1
Widmer, M.B.2
Finkelman, F.D.3
Madani, H.4
Jacobs, C.A.5
Grabstein, K.H.6
Maliszewski, C.R.7
-
124
-
-
0031572240
-
Regulation of the expression of the soluble and membrane forms of the murine IL-4 receptor
-
CHILTON, P. M., and R. FERNANDEZ-BOTRAN. 1997. Regulation of the expression of the soluble and membrane forms of the murine IL-4 receptor. Cell Immunol 180: 104.
-
(1997)
Cell Immunol
, vol.180
, pp. 104
-
-
Chilton, P.M.1
Fernandez-Botran, R.2
-
125
-
-
0028904642
-
Linked in vivo expression of soluble interleukin-4 receptor and interleukin-4 in murine schistosomiasis
-
FERNANDFZ-BOTRAN, R., T. A. WYNN, S. HIENY, P. CASPAR, P. M. CHILTON, and A. SHER. 1995. Linked in vivo expression of soluble interleukin-4 receptor and interleukin-4 in murine schistosomiasis. Eur J Immunol 25: 649.
-
(1995)
Eur J Immunol
, vol.25
, pp. 649
-
-
Fernandfz-Botran, R.1
Wynn, T.A.2
Hieny, S.3
Caspar, P.4
Chilton, P.M.5
Sher, A.6
-
126
-
-
0030239647
-
Two distinct stimulus-dependent pathways lead to production of soluble murine interleukin-4 receptor
-
BLUM, H., M. WOLF, K. ENSSLE, M. ROLLINGHOFF, and A. GESSNER. 1996. Two distinct stimulus-dependent pathways lead to production of soluble murine interleukin-4 receptor. J Immunol 157: 1846.
-
(1996)
J Immunol
, vol.157
, pp. 1846
-
-
Blum, H.1
Wolf, M.2
Enssle, K.3
Rollinghoff, M.4
Gessner, A.5
-
127
-
-
0032933516
-
Soluble human interleukin-4 receptor is produced by activated T cells under the control of metallo-proteinases
-
JUNG, T., N. SCHRADER, M. HELLWIG, C. ENSSLEX, and C. NEUMANN. 1999. Soluble human interleukin-4 receptor is produced by activated T cells under the control of metallo-proteinases. Int Arch Allergy Immunol 119: 23.
-
(1999)
Int Arch Allergy Immunol
, vol.119
, pp. 23
-
-
Jung, T.1
Schrader, N.2
Hellwig, M.3
Ensslex, C.4
Neumann, C.5
-
128
-
-
0030975719
-
Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chains
-
ZHANG, J. G., D. J. HILTON, T. A. WILLSON, C. MCFARLANE, B. A. ROBERTS, R. L. MORITZ, R. J. SIMPSON, W. S. ALEXANDER, D. METCALF, and N. A. NICOLA. 1997. Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chains. J Biol Chem 272: 9474.
-
(1997)
J Biol Chem
, vol.272
, pp. 9474
-
-
Zhang, J.G.1
Hilton, D.J.2
Willson, T.A.3
McFarlane, C.4
Roberts, B.A.5
Moritz, R.L.6
Simpson, R.J.7
Alexander, W.S.8
Metcalf, D.9
Nicola, N.A.10
-
129
-
-
0033555809
-
IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs
-
CHIARAMONTE, M. G., L. R. SCHOPF, T. Y. NEBEN, A. W. CHEEVER, D. D. DONALDSON, and T. A. WYNN. 1999. IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs. J Immunol 162: 920.
-
(1999)
J Immunol
, vol.162
, pp. 920
-
-
Chiaramonte, M.G.1
Schopf, L.R.2
Neben, T.Y.3
Cheever, A.W.4
Donaldson, D.D.5
Wynn, T.A.6
-
130
-
-
0033178738
-
A soluble form of IL-13 receptor alpha 1 promotes IgG2a and IgG2b production by murine germinal center B cells
-
POUDRIER, J., P GRABER., S. HERREN, D. GRETENER, G. ELSON, C. BERNEY, J. F. GAUCHAT, and M. H. KOSCO-VILBOIS. 1999. A soluble form of IL-13 receptor alpha 1 promotes IgG2a and IgG2b production by murine germinal center B cells. J Immunol 163: 1153.
-
(1999)
J Immunol
, vol.163
, pp. 1153
-
-
Poudrier, J.1
Graber, P.2
Herren, S.3
Gretener, D.4
Elson, G.5
Berney, C.6
Gauchat, J.F.7
Kosco-Vilbois, M.H.8
-
131
-
-
0030670147
-
Molecular characterization and functional analysis of murine interleukm 4 receptor allotypes
-
SCHULTE, T., R. KURRLE, M. ROLLINGHOFF, and A. GESSNER. 1997. Molecular characterization and functional analysis of murine interleukm 4 receptor allotypes. J Exp Med 186: 1419.
-
(1997)
J Exp Med
, vol.186
, pp. 1419
-
-
Schulte, T.1
Kurrle, R.2
Rollinghoff, M.3
Gessner, A.4
-
132
-
-
0032499069
-
The interleukin-4 receptor variant Q576R in hyper-IgE syndrome
-
GRIMBACHER, B., S. M. HOLLAND, and J. M. PUCK. 1998. The interleukin-4 receptor variant Q576R in hyper-IgE syndrome [letter; comment]. N Engl J Med 338: 1073.
-
(1998)
N Engl J Med
, vol.338
, pp. 1073
-
-
Grimbacher, B.1
Holland, S.M.2
Puck, J.M.3
-
133
-
-
0032981094
-
The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction
-
KRUSE, S., T. JAPHA, M. TEDNER, S. H. SPARHOLT, J. FORSTER, J. KUEHR, and K. A. DEICHMANN. 1999. The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction. Immunology 96: 365.
-
(1999)
Immunology
, vol.96
, pp. 365
-
-
Kruse, S.1
Japha, T.2
Tedner, M.3
Sparholt, S.H.4
Forster, J.5
Kuehr, J.6
Deichmann, K.A.7
-
134
-
-
0032703486
-
The IL-4 receptor alpha-chain variant Q576R is strongly associated with decreased kidney allograft survival
-
in press
-
HACKSTEIN, H., H. KLÜTER, L. FRICKE, J. HOYER, and G. BEIN. 1999. The IL-4 receptor alpha-chain variant Q576R is strongly associated with decreased kidney allograft survival. Tissue antigens in press.
-
(1999)
Tissue Antigens
-
-
Hackstein, H.1
Klüter, H.2
Fricke, L.3
Hoyer, J.4
Bein, G.5
-
135
-
-
0032712285
-
Definition of human interleukin-4 receptor alpha chain haplotypes and allelic association with atopy markers
-
in press
-
HACKSTEIN, H., H. HOFMANN, A. BOHNERT, and G. BEIN. 1999. Definition of human interleukin-4 receptor alpha chain haplotypes and allelic association with atopy markers. Human Immunol. in press.
-
(1999)
Human Immunol.
-
-
Hackstein, H.1
Hofmann, H.2
Bohnert, A.3
Bein, G.4
-
136
-
-
0033045458
-
Lack of association of atopy/asthma and the interleukin-4 receptor alpha gene in Japanese
-
NOGUCHI, E., M. SHIBASAKI, T. ARINAMI, K. TAKEDA, Y YOKOUCHI., K. KOBAYASHI, N. IMOTO, S. NAKAHARA, A. MATSUI, and H. HAMAGUCHI. 1999. Lack of association of atopy/asthma and the interleukin-4 receptor alpha gene in Japanese. Clin Exp Allergy 29: 228.
-
(1999)
Clin Exp Allergy
, vol.29
, pp. 228
-
-
Noguchi, E.1
Shibasaki, M.2
Arinami, T.3
Takeda, K.4
Yokouchi, Y.5
Kobayashi, K.6
Imoto, N.7
Nakahara, S.8
Matsui, A.9
Hamaguchi, H.10
-
137
-
-
18844480971
-
Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma
-
MITSUYASU, H., K. IZUHARA, X. Q. MAO, P. S. GAO, Y. ARINOBU, T. ENOMOTO, M. KAWAI, S. SASAKI, Y DAKE., N. HAMASAKI, T. SHIRAKAWA, and J. M. HOPKIN. 1998. Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma [letter]. Nat Genet 19: 119.
-
(1998)
Nat Genet
, vol.19
, pp. 119
-
-
Mitsuyasu, H.1
Izuhara, K.2
Mao, X.Q.3
Gao, P.S.4
Arinobu, Y.5
Enomoto, T.6
Kawai, M.7
Sasaki, S.8
Dake, Y.9
Hamasaki, N.10
Shirakawa, T.11
Hopkin, J.M.12
-
138
-
-
0001325237
-
The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor [see comments]
-
HERSHEY, G. K., M. F. FRIEDRICH, L. A. ESSWEIN, M. L. THOMAS, and T. A. CHATILA. 1997. The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor [see comments]. N Engl J Med 337: 1720.
-
(1997)
N Engl J Med
, vol.337
, pp. 1720
-
-
Hershey, G.K.1
Friedrich, M.F.2
Esswein, L.A.3
Thomas, M.L.4
Chatila, T.A.5
-
139
-
-
0033561683
-
Cutting edge: Effects of an allergy-associated mutation in the human IL-4R alpha (Q576R) on human IL-4-induced signal transduction
-
WANG, H. Y., C. P. SHELBURNE, J. ZAMORANO, A. E. KELLY, J. J. RYAN, and A. D. KEEGAN. 1999. Cutting edge: effects of an allergy-associated mutation in the human IL-4R alpha (Q576R) on human IL-4-induced signal transduction. J Immunol 162: 4385.
-
(1999)
J Immunol
, vol.162
, pp. 4385
-
-
Wang, H.Y.1
Shelburne, C.P.2
Zamorano, J.3
Kelly, A.E.4
Ryan, J.J.5
Keegan, A.D.6
-
140
-
-
0033083286
-
Cutting edge: Dominant effect of Ile50Val variant of the human IL-4 receptor alpha-chain in IgE synthesis
-
MITSUYASU, H., Y. YANAGIHARA, X. Q. MAO, P. S. GAO, Y ARINOBU., K. IHARA, A. TAKABAYASHI, T. HARA, T. ENOMOTO, S. SASAKI, M. KAWAI, N. HAMASAKI, T. SHIRAKAWA, J. M. HOPKIN, and K. IZUHARA. 1999. Cutting edge: dominant effect of Ile50Val variant of the human IL-4 receptor alpha-chain in IgE synthesis. J Immunol 162: 1227.
-
(1999)
J Immunol
, vol.162
, pp. 1227
-
-
Mitsuyasu, H.1
Yanagihara, Y.2
Mao, X.Q.3
Gao, P.S.4
Arinobu, Y.5
Ihara, K.6
Takabayashi, A.7
Hara, T.8
Enomoto, T.9
Sasaki, S.10
Kawai, M.11
Hamasaki, N.12
Shirakawa, T.13
Hopkin, J.M.14
Izuhara, K.15
-
141
-
-
0031584822
-
Common polymorphisms in the coding part of the IL4-receptor gene
-
DEICHMANN, K., J. BARDUTZKY, J. FORSTER, A. HEINZMANN, and J. KUEHR. 1997. Common polymorphisms in the coding part of the IL4-receptor gene. Biochem Biophys Res Commun 231: 696.
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 696
-
-
Deichmann, K.1
Bardutzky, J.2
Forster, J.3
Heinzmann, A.4
Kuehr, J.5
-
142
-
-
0032988804
-
Interleukin-4 and interleukin-4 receptor polymorphisms in minimal change nephropathy
-
Colch
-
PARRY, R. G., K. M. GILLESPIE, A. PARNHAM, A. G. CLARK, and P. W. MATHIESON. 1999. Interleukin-4 and interleukin-4 receptor polymorphisms in minimal change nephropathy. Clin Sci (Colch) 96: 665.
-
(1999)
Clin Sci
, vol.96
, pp. 665
-
-
Parry, R.G.1
Gillespie, K.M.2
Parnham, A.3
Clark, A.G.4
Mathieson, P.W.5
-
143
-
-
0033031986
-
Association of interleukin-4 receptor and interleukin-4 promoter gene polymorphisms with systemic lupus erythematosus
-
KANEMITSU, S., A. TAKABAYASHI, Y. SASAKI, R. KUROMARU, K. IHARA, Y. KAKU, K. SAKAI, and T. HARA. 1999. Association of interleukin-4 receptor and interleukin-4 promoter gene polymorphisms with systemic lupus erythematosus. Arthritis Rheum 42: 1298.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 1298
-
-
Kanemitsu, S.1
Takabayashi, A.2
Sasaki, Y.3
Kuromaru, R.4
Ihara, K.5
Kaku, Y.6
Sakai, K.7
Hara, T.8
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