Molecular characterization and functional analysis of murine interleukin 4 receptor allotypes

Journal of Experimental Medicine

Volumn 186, Issue 9, 1997, Pages 1419-1429

  Schulte, T ^a   Kurrle, R ^b   Rollinghoff M ^a   Gessner, A ^a,c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b Behringwerke AG   (Germany)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; INTERLEUKIN 4 RECEPTOR; ISOLEUCINE; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; THREONINE;

ALLOTYPE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DISSOCIATION; FEMALE; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ALLELES; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BASE SEQUENCE; BINDING SITES, ANTIBODY; CELL MEMBRANE; DNA RESTRICTION ENZYMES; EPITOPE MAPPING; EXTRACELLULAR SPACE; FEMALE; GLYCOSYLATION; KINETICS; MICE; MICE, INBRED AKR; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, INBRED DBA; MICE, SCID; RECEPTORS, INTERLEUKIN-4;

EID: 0030670147     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.9.1419     Document Type: Article

References (47)

1. Keegan, A.D., and W.E. Paul. 1992. Multichain immune recognition receptors: similarities in structure and signaling pathways. Immunol. Today. 13:63-68.
2. Paul, W.E. 1991. Interleukin 4: a prototypic immunoregulatory lymphokine. Blood. 77:1859-1870.
3. Bogdan, C., and C. Nathan. 1993. Modulation of macrophage function by transforming growth factor β, interleukin 4, and interleukin 10. Ann. NY Acad. Sci. 685:713-739.
4. Sadick, M.D., F.P. Heinzel, B.J. Holaday, R.T. Pu, R.S. Dawkins, and R.M. Locksley. 1990. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon γ-independent mechanism. J. Exp. Med. 171:115-127.
5. Romani, L., A. Mencacci, U. Grohmann, S. Mocci, P. Mosci, P. Puccetti, and F. Bistoni. 1992. Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis. J. Exp. Med. 176:19-25.
6. Gessner, A., K. Schröppel, A. Will, K.H. Enssle, L. Lauffer, and M. Röllinghoff. 1994. Recombinant soluble interleukin 4 (IL-4) receptor acts as an antagonist of IL-4 in murine cutaneous Leishmaniasis. Infect. Immun. 62:4112-4117.
7. Puccetti, P., A. Mencacci, E. Cenci, R. Spaccapelo, P. Mosci, K.H. Enssle, L. Romani, and F. Bistoni. 1994. Cure of murine candidiasis by recombinant soluble interleukin-4 receptor. J. Infect. Dis. 169:1325-1331.
8. Kopf, M., G. Le Gros, M. Bachmann, M.C. Lamers, H. Bluethmann, and G. Kohler. 1993. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature (Lond.). 362:245-248.
9. Bogdan, C., A. Gessner, W. Solbach, and M. Röllinghoff. 1996. Invasion, control and persistence of Leishmania parasites. Curr. Opin. Immunol. 8:517-525.
10. Abbas, A.K., K.M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature (Lond.). 383:787-793.
11. Chen, Y., V. Kuchroo, J.I. Inobe, D.A. Hafler, and H.L. Weiner. 1994. Regulatory T cell clones induced by oral tolerance and suppression of autoimmune encephalomyelitis. Science (Wash. DC). 265:1237-1240.
12. Santiago, M.-L., L. Fossati, C. Jacquet, W. Müller, S. Izui, and L. Reininger. 1997. Interleukin 4 protects against a genetically linked lupus-like autoimmune syndrome. J. Exp. Med. 185:65-70.
13. Lowenthal, J.W., B.E. Castle, J. Christiansen, J. Schreurs, D. Rennick, N. Arai, P. Hoy, Y. Takebe, and M. Howard. 1988. Expression of high affinity receptors for murine interleukin 4 (BSF-1) on hemopoietic and nonhemopoietic cells. J. Immunol. 140:456-464.
14. Kondo, M., T. Takeshita, N. Ishii, M. Nakamura, S. Watanabe, K. Arai, and K. Sugamura. 1993. Sharing of the interleukin 2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4. Science (Wash. DC). 262:1874-1877.
15. Mosley, B., M.P. Beckmann, C.J. March, R.L. Idzerda, S.D. Gimpel, T. Vanden Bos, D. Friend, A. Alpert, D. Anderson, J. Jackson, et al. 1989. The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms. Cell. 59:335-348.
16. Harada, N., B.E. Castle, D.M. Gorman, N. Itoh, J. Schreurs, R.L. Barrett, M. Howard, and A. Miyajima. 1990. Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding. Proc. Natl. Acad. Sci. USA. 87:857-861.
17. Idzerda, R.L., C.J. March, B. Mosley, S.D. Lyman, T. Vanden Bos, S.D. Gimpel, W.S. Din, K.H. Grabstein, M.B. Widmer, L.S. Park, et al. 1990. Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily. J. Exp. Med. 171:861-873.
18. Galizzi, J.P., C.E. Zuber, N. Harada, D.M. Gorman, O. Djossou, R. Kastelein, J. Banchereau, M. Howard, and A. Miyajima. 1990. Molecular cloning of a cDNA encoding the human interleukin 4 receptor. Int. Immunol. 2:669-675.
19. Matesanz, F., and A. Alcina. 1996. Glutamine and tetrapeptide repeat variations affect the biological activity of different mouse interleukin 2 alleles. Eur. J. Immunol. 26:1675-1682.
20. Samson, M., F. Libert, B.J. Doranz, J. Rucker, C. Liesnard, C.M. Farber, S. Saragosti, C. Lapounieroulie, J. Cognaux, C. Forceille, et al. 1996. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature (Lond.). 382:722-725.
21. Takahashi, T., M. Tanaka, C.I. Brannan, N.A. Jenkins, N.G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell. 76:969-976.
22. Baumann, H., K. K. Morella, D.W. White, M. Dembski, P.S. Bailon, H. Kim, C.F. Lai, and L.A. Tartaglia. 1996. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. Proc. Natl. Acad. Sci. USA. 93: 8374-8378.
23. Lohoff, M., M. Dirks, P. Rohwer, and M. Röllinghoff. 1989. Studies on the mechanism of polyclonal B cell stimulation by TH2 cells. Eur. J. Immunol. 19:77-81.
24. Kitamura, T., T. Tange, T. Terasawa, S. Chiba, T. Kuwaki, K. Miyagawa, Y.F. Piao, K. Miyazono, A. Urabe, and F. Takaku. 1989. Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J. Cell. Physiol. 140:323-334.
25. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal. Biohem. 162:156-159.
26. Wrighton, N., L.A. Campbell, N. Harada, A. Miyajima, and F. Lee. 1992. The murine interleukin-4 receptor gene: genomic structure, expression and potential for alternative splicing. Growth Factors. 6:103-118.
27. Gustchina, A., A. Zdanov, C. Schalk-Hihi, and A. Wlodawer. 1995. A model of the complex between interleukin-4 and its receptors. Proteins. 21:140-148.
28. Wyss, D.F., J.S. Choi, J. Li, M.H. Knoppers, K.J. Willis, A.K. Arulanandam, A. Smolyar, E.L. Reinherz, and G. Wagner. 1995. Conformation and function of the N-linked glycan in the adhesion domain of human CD2. Science (Wash. DC). 269:1273-1278.
29. Fischer, T., B. Thoma, P. Scheurich, and K. Pfizenmaier. 1990. Glycosylation of the human interferon-γ receptor. N-linked carbohydrates contribute to structural heterogeneity and are required for ligand binding. J. Biol. Chem. 265:1710-1717.
30. Feige, J.J., and A. Baird. 1988. Glycosylation of the basic fibroblast growth factor receptor. The contribution of carbohydrate to receptor function. J. Biol. Chem. 263:14023-14029.
31. Soderquist, A.M., and G. Carpenter. 1984. Glycosylation of the epidermal growth factor receptor in A-431 cells. The contribution of carbohydrate to receptor function. J. Biol. Chem. 259:12586-12594.
32. Ronnett, G.V., and M.D. Lane. 1981. Post-translational glycosylation-induced activation of aglycoinsulin receptor accumulated during tunicamycin treatment. J. Biol. Chem. 256: 4704-4707.
33. Keinanen, K.P. 1988. Effect of deglycosylation on the structure and hormone-binding activity of the lutropin receptor. Biochem. J. 256:719-724.
34. Boege, F., M. Ward, K. Jurss, M. Hekman, and E.J. Helmreich. 1988. Role of glycosylation for β 2-adrenoceptor function in A431 cells. J. Biol. Chem. 263:9040-9049.
35. Johnson, K., Y. Choi, Z. Wu, T. Ciardelli, R. Granzow, C. Whalen, T. Sana, G. Pardee, K. Smith, and A. Creasey. 1994. Soluble IL-2 receptor β and γ subunits: ligand binding and cooperativity. Eur. Cytokine. Netw. 5:23-34.
36. + T cells. Annu. Rev. Immunol. 12:635-673.
37. Perez, V.L., J.A. Lederer, A.H. Lichtman, and A.K. Abbas. 1995. Stability of Th1 and Th2 populations. Int. Immunol. 7: 869-875.
38. + T cells during initiation of infection. J. Exp. Med. 179:447-456.
39. Scott, P. 1991. IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J. Immunol. 147:3149-3155.
40. Hsieh, C.S., S.E. Macatonia, A. O'Garra, and K.M. Murphy. 1995. T cell genetic background determines default T helper phenotype development in vitro. J. Exp. Med. 181:713-721.
41. Hsieh, C.S., A.B. Heimberger, J.S. Gold, A. O'Garra, and K.M. Murphy. 1992. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an αβ T-cell receptor transgenic system. Proc. Natl. Acad. Sci. USA 89: 6065-6069.
42. + T cells from T cell receptor transgenic mice. J. Exp. Med. 176:1091-1098.
43. Demant, P., M. Lipoldova, and M. Svobodova. 1996. Resistance to Leishmania major in mice. Science (Wash. DC). 274: 1392-1393.
44. Baker, D., O.A. Rosenwasser, J.K. O'Neill, and J.L. Turk. 1995. Genetic analysis of experimental allergic encephalomyelitis in mice. J. Immunol. 155:4046-4051.
45. Kuchroo, V.K., C.A. Martin, J.M. Greer, S.T. Ju, R.A. Sobel, and M.E. Dorf. 1993. Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis. J. Immunol. 151:4371-4382.
46. Drake, C.G., S.J. Rozzo, H.F. Hirschfeld, N.P. Smarnworawong, E. Palmer, and B.L. Kotzin. 1995. Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner. J. Immunol. 154:2441-2447.
47. Fernandez-Botran, R., P.M. Chilton, Y. Ma, J.L. Windsor, and N.E. Street. 1996. Control of the production of soluble interleukin-4 receptors: implications in immunoregulation. J. Leukocyte Biol. 59:499-504.