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Volumn 91, Issue 7, 1998, Pages 2547-2557

Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper 2-derived cytokines interleukin-4 and interleukin-5

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; INTERLEUKIN 5; RANTES; THROMBOCYTE ACTIVATING FACTOR; ZYMOSAN;

EID: 0032055541     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.7.2547     Document Type: Article
Times cited : (107)

References (68)
  • 1
    • 0026687304 scopus 로고
    • The pathobiology of bronchial asthma
    • Arm JP, Lee TH: The pathobiology of bronchial asthma. Adv Immunol 51:323, 1992
    • (1992) Adv Immunol , vol.51 , pp. 323
    • Arm, J.P.1    Lee, T.H.2
  • 4
    • 0027178695 scopus 로고
    • Relative contributions of human types 1 and 2 T-helper cell-derived eosinophilotrophic cytokines to development of eosinophilia
    • Wierenga EA, Backx B, Snoek M, Koenderman L, Kapsenberg ML: Relative contributions of human types 1 and 2 T-helper cell-derived eosinophilotrophic cytokines to development of eosinophilia. Blood 82:1471, 1993
    • (1993) Blood , vol.82 , pp. 1471
    • Wierenga, E.A.1    Backx, B.2    Snoek, M.3    Koenderman, L.4    Kapsenberg, M.L.5
  • 5
    • 0025805857 scopus 로고
    • T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma
    • Walker C, Virchow JCJ, Bruijnzeel PLB, Blaser K: T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. J Immunol 146:1829, 1991
    • (1991) J Immunol , vol.146 , pp. 1829
    • Walker, C.1    Virchow, J.C.J.2    Bruijnzeel, P.L.B.3    Blaser, K.4
  • 6
    • 0027466759 scopus 로고
    • CD4 T-lymphocyte activation in asthma is accompanied by increased serum concentrations of interleukin-5. Effect of glucocorticoid therapy
    • Corrigan CJ, Haczku A, Gemou Engesaeth V, Doi S, Kikuchi Y, Takatsu K, Durham SR, Kay AB: CD4 T-lymphocyte activation in asthma is accompanied by increased serum concentrations of interleukin-5. Effect of glucocorticoid therapy. Am Rev Respir Dis 147:540, 1993
    • (1993) Am Rev Respir Dis , vol.147 , pp. 540
    • Corrigan, C.J.1    Haczku, A.2    Gemou Engesaeth, V.3    Doi, S.4    Kikuchi, Y.5    Takatsu, K.6    Durham, S.R.7    Kay, A.B.8
  • 7
    • 0002814860 scopus 로고
    • Cytokine regulation of eosinophil-mediated inflammatory reactions by modulation of eosinophil programmed cell death and subsequent priming for augmented function
    • Gleich GJ, Kay AB (eds): New York, NY, Marcel Dekker
    • Owen WF, Austen KF: Cytokine regulation of eosinophil-mediated inflammatory reactions by modulation of eosinophil programmed cell death and subsequent priming for augmented function, in Gleich GJ, Kay AB (eds): Eosinophils in Allergy and Inflammation. New York, NY, Marcel Dekker, 1994, p 239
    • (1994) Eosinophils in Allergy and Inflammation , pp. 239
    • Owen, W.F.1    Austen, K.F.2
  • 8
    • 0025856894 scopus 로고
    • Modulation and induction of eosinophil chemotaxis by granulocytemacrophage colony-stimulating factor and interleukin-3
    • Warringa RAJ, Koenderman L, Kok PTM, Kreukniet J, Bruijnzeel PLB: Modulation and induction of eosinophil chemotaxis by granulocytemacrophage colony-stimulating factor and interleukin-3. Blood 77: 2694, 1991
    • (1991) Blood , vol.77 , pp. 2694
    • Warringa, R.A.J.1    Koenderman, L.2    Kok, P.T.M.3    Kreukniet, J.4    Bruijnzeel, P.L.B.5
  • 9
    • 0028238761 scopus 로고
    • RANTES- and interleukin-8-induced responses in normal human eosinophils: Effects of priming with interleukin-5
    • Schweizer RC, Welmers BA, Raaijmakers JAM, Zanen P, Lammers J-W, Koenderman L: RANTES- and interleukin-8-induced responses in normal human eosinophils: Effects of priming with interleukin-5. Blood 83:3697, 1994
    • (1994) Blood , vol.83 , pp. 3697
    • Schweizer, R.C.1    Welmers, B.A.2    Raaijmakers, J.A.M.3    Zanen, P.4    Lammers, J.-W.5    Koenderman, L.6
  • 12
    • 0030272581 scopus 로고    scopus 로고
    • Roles of the JAK-STAT system in signal transduction via cytokine receptors
    • Watanabe S, Arai K-I: Roles of the JAK-STAT system in signal transduction via cytokine receptors. Curr Opin Genet Dev 6:587, 1996
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 587
    • Watanabe, S.1    Arai, K.-I.2
  • 13
    • 0028557450 scopus 로고
    • Chemokines, leukocyte trafficking and inflammation
    • Schall TJ, Bacon KB: Chemokines, leukocyte trafficking and inflammation. Curr Opin Immunol 6:865, 1994
    • (1994) Curr Opin Immunol , vol.6 , pp. 865
    • Schall, T.J.1    Bacon, K.B.2
  • 14
    • 0027976137 scopus 로고
    • Mechanisms of leukocyte motility and chemotaxis
    • Downey GP: Mechanisms of leukocyte motility and chemotaxis. Curr Opin Immunol 6:113, 1994
    • (1994) Curr Opin Immunol , vol.6 , pp. 113
    • Downey, G.P.1
  • 15
    • 0030742813 scopus 로고    scopus 로고
    • Granulocyte priming: Cause without effect?
    • Coffer PJ, Koenderman L: Granulocyte priming: Cause without effect? Immunol Lett 57:27, 1997
    • (1997) Immunol Lett , vol.57 , pp. 27
    • Coffer, P.J.1    Koenderman, L.2
  • 17
    • 0028486018 scopus 로고
    • Phosphatidylinositol 3-kinase
    • Kapeller R, Cantley LC: Phosphatidylinositol 3-kinase. Bioessays 16:565, 1994
    • (1994) Bioessays , vol.16 , pp. 565
    • Kapeller, R.1    Cantley, L.C.2
  • 19
    • 0028334738 scopus 로고
    • A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits
    • Stephens L, Smrcka A, Cooke FT, Jackson TR, Sternweis PC, Hawkins PT: A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits. Cell 77:83, 1994
    • (1994) Cell , vol.77 , pp. 83
    • Stephens, L.1    Smrcka, A.2    Cooke, F.T.3    Jackson, T.R.4    Sternweis, P.C.5    Hawkins, P.T.6
  • 22
    • 0027535742 scopus 로고
    • Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate
    • Nakanishi H, Brewer KA, Exton JH: Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 268:13, 1993
    • (1993) J Biol Chem , vol.268 , pp. 13
    • Nakanishi, H.1    Brewer, K.A.2    Exton, J.H.3
  • 24
    • 0029084949 scopus 로고
    • Phosphatidylinositol (3,4,5)-trisphosphate stimulates phosphorylation of pleckstrin in human platelets
    • Zhang J, Falck JR, Reddy KK, Abrams CS, Zhao W, Rittenhouse SE: Phosphatidylinositol (3,4,5)-trisphosphate stimulates phosphorylation of pleckstrin in human platelets. J Biol Chem 270:22807, 1995
    • (1995) J Biol Chem , vol.270 , pp. 22807
    • Zhang, J.1    Falck, J.R.2    Reddy, K.K.3    Abrams, C.S.4    Zhao, W.5    Rittenhouse, S.E.6
  • 27
    • 0028021882 scopus 로고
    • Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
    • Harlan JE, Hajduk PJ, Yoon HS, Fesik SW: Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature 371: 168, 1994
    • (1994) Nature , vol.371 , pp. 168
    • Harlan, J.E.1    Hajduk, P.J.2    Yoon, H.S.3    Fesik, S.W.4
  • 28
    • 0029087181 scopus 로고
    • Structural characterization of the interaction between a pleckstrin homology domain and phosphatidylinositol 4,5-bisphosphate
    • Harlan JE, Yoon HS, Hajduk PJ, Fesik SW: Structural characterization of the interaction between a pleckstrin homology domain and phosphatidylinositol 4,5-bisphosphate. Biochemistry 34:9859, 1995
    • (1995) Biochemistry , vol.34 , pp. 9859
    • Harlan, J.E.1    Yoon, H.S.2    Hajduk, P.J.3    Fesik, S.W.4
  • 31
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering BMTh, Coffer PJ: Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599, 1995
    • (1995) Nature , vol.376 , pp. 599
    • Burgering, B.M.Th.1    Coffer, P.J.2
  • 32
    • 0030265564 scopus 로고    scopus 로고
    • Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase
    • Didichenko SA, Tlton B, Hemmings BA, Ballmer-Hofer K, Thelen M: Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase. Curr Biol 6:1271, 1996
    • (1996) Curr Biol , vol.6 , pp. 1271
    • Didichenko, S.A.1    Tlton, B.2    Hemmings, B.A.3    Ballmer-Hofer, K.4    Thelen, M.5
  • 33
    • 0028956998 scopus 로고
    • The intracellular signal transduction mechanism of interleukin 5 in eosinophils: The involvement of Lyn tyrosine kinase and Ras-Raf-MEK-microtubule-associated protein kinase pathway
    • Pazdrak K, Schreiber D, Forsythe P, Justement L, Alam R: The intracellular signal transduction mechanism of interleukin 5 in eosinophils: The involvement of Lyn tyrosine kinase and Ras-Raf-MEK-microtubule-associated protein kinase pathway. J Exp Med 181:1827, 1995
    • (1995) J Exp Med , vol.181 , pp. 1827
    • Pazdrak, K.1    Schreiber, D.2    Forsythe, P.3    Justement, L.4    Alam, R.5
  • 34
    • 0028142461 scopus 로고
    • The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation
    • El Benna J, Faust LP, Babior BM: The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. J Biol Chem 269:23431, 1994
    • (1994) J Biol Chem , vol.269 , pp. 23431
    • El Benna, J.1    Faust, L.P.2    Babior, B.M.3
  • 35
    • 0029983262 scopus 로고    scopus 로고
    • Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase a and mitogen-activated protein kinase
    • El Benna J, Faust LP, Johnson JL, Babior BM: Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A and mitogen-activated protein kinase. J Biol Chem 271:6374, 1996
    • (1996) J Biol Chem , vol.271 , pp. 6374
    • El Benna, J.1    Faust, L.P.2    Johnson, J.L.3    Babior, B.M.4
  • 36
    • 0028051746 scopus 로고
    • Tyrosine phosphorylation and activation of NADPH oxidase in human neutrophils: A possible role for Map kinases and for a 75 kDa protein
    • Dusi S, Donini M, Rossi F: Tyrosine phosphorylation and activation of NADPH oxidase in human neutrophils: A possible role for Map kinases and for a 75 kDa protein. Biochem J 304:243, 1994
    • (1994) Biochem J , vol.304 , pp. 243
    • Dusi, S.1    Donini, M.2    Rossi, F.3
  • 37
    • 0023812908 scopus 로고
    • An improved method for the isolation of eosinophilic granulocytes from peripheral blood of normal individuals
    • Koenderman L, Kok PT, Hamelink ML, Verhoeven AJ, Bruijnzeel PLB: An improved method for the isolation of eosinophilic granulocytes from peripheral blood of normal individuals. J Leukoc Biol 44:79, 1988
    • (1988) J Leukoc Biol , vol.44 , pp. 79
    • Koenderman, L.1    Kok, P.T.2    Hamelink, M.L.3    Verhoeven, A.J.4    Bruijnzeel, P.L.B.5
  • 39
    • 0026555136 scopus 로고
    • IFN-gamma induces expression of Fc gamma RIII (CD16) on human eosinophils
    • Hartnell A, Kay AB, Wardlaw AJ: IFN-gamma induces expression of Fc gamma RIII (CD16) on human eosinophils. J Immunol 148:1471, 1992
    • (1992) J Immunol , vol.148 , pp. 1471
    • Hartnell, A.1    Kay, A.B.2    Wardlaw, A.J.3
  • 40
    • 0031055415 scopus 로고    scopus 로고
    • Minimal Ras-binding domain of raf1 can be used as an activation-specific probe for Ras
    • de Rooij J, Bos JL: Minimal Ras-binding domain of raf1 can be used as an activation-specific probe for Ras. Oncogene 14:623, 1997
    • (1997) Oncogene , vol.14 , pp. 623
    • De Rooij, J.1    Bos, J.L.2
  • 42
    • 0016375453 scopus 로고
    • Oxygen consumption of phagocytizing cells in human leukocyte and granulocyte preparations: A comparative study
    • Weening RS, Roos D, Loos JA: Oxygen consumption of phagocytizing cells in human leukocyte and granulocyte preparations: A comparative study. J Lab Clin Med 83:570, 1974
    • (1974) J Lab Clin Med , vol.83 , pp. 570
    • Weening, R.S.1    Roos, D.2    Loos, J.A.3
  • 43
    • 0010351539 scopus 로고
    • Human eosinophils express a functional IL-4 receptor; IL-4 induced activation of eosinophil chemotactic responses
    • Dubois GR, Bruijnzeel-Koomen CAFM, Bruijnzeel PLB: Human eosinophils express a functional IL-4 receptor; IL-4 induced activation of eosinophil chemotactic responses. Immunology 86:91, 1995 (suppl 1)
    • (1995) Immunology , vol.86 , Issue.1 SUPPL. , pp. 91
    • Dubois, G.R.1    Bruijnzeel-Koomen, C.A.F.M.2    Bruijnzeel, P.L.B.3
  • 45
    • 0027930914 scopus 로고
    • FMLP activates Ras and raf in human neutrophils. Potential role in activation of MAP kinase
    • Worthen GS, Avdi N, Buhl AM, Suzuki N, Johnson GL: FMLP activates Ras and raf in human neutrophils. Potential role in activation of MAP kinase. J Clin Invest 94:815, 1994
    • (1994) J Clin Invest , vol.94 , pp. 815
    • Worthen, G.S.1    Avdi, N.2    Buhl, A.M.3    Suzuki, N.4    Johnson, G.L.5
  • 46
    • 0027958335 scopus 로고
    • Transfected platelet-activating factor receptor activates mitogen-activated protein (MAP) kinase and MAP kinase in Chinese hamster ovary cells
    • Honda Z, Takano T, Gotoh Y, Nishida E, Ito K, Shimizu T: Transfected platelet-activating factor receptor activates mitogen-activated protein (MAP) kinase and MAP kinase in Chinese hamster ovary cells. J Biol Chem 269:2307, 1994
    • (1994) J Biol Chem , vol.269 , pp. 2307
    • Honda, Z.1    Takano, T.2    Gotoh, Y.3    Nishida, E.4    Ito, K.5    Shimizu, T.6
  • 47
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo
    • Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR: PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo. J Biol Chem 270:27489, 1995
    • (1995) J Biol Chem , vol.270 , pp. 27489
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 49
    • 0024532732 scopus 로고
    • Dual mechanisms in priming of the chemoattractant-induced respiratory burst in human granulocytes
    • Koenderman L, Yazdanbakhsh M, Roos D, Verhoeven AJ: Dual mechanisms in priming of the chemoattractant-induced respiratory burst in human granulocytes. J Immunol 142:623, 1989
    • (1989) J Immunol , vol.142 , pp. 623
    • Koenderman, L.1    Yazdanbakhsh, M.2    Roos, D.3    Verhoeven, A.J.4
  • 52
    • 0027219258 scopus 로고
    • A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor
    • Ponzetto C, Bardelli A, Maina F, Longati P, Panayotou G, Dhand R, Waterfield MD, Comoglio PM: A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor. Mol Cell Biol 13:4600, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 4600
    • Ponzetto, C.1    Bardelli, A.2    Maina, F.3    Longati, P.4    Panayotou, G.5    Dhand, R.6    Waterfield, M.D.7    Comoglio, P.M.8
  • 53
    • 0028874966 scopus 로고
    • Identification of a new adapter protein that may link the common beta subunit of the receptor for granulocyte/ macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 to phosphatidylinositol 3-kinase
    • Jucker M, Feldman RA: Identification of a new adapter protein that may link the common beta subunit of the receptor for granulocyte/ macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 to phosphatidylinositol 3-kinase. J Biol Chem 270:27817, 1995
    • (1995) J Biol Chem , vol.270 , pp. 27817
    • Jucker, M.1    Feldman, R.A.2
  • 54
    • 0028198388 scopus 로고
    • Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit
    • Pleiman CM, Hertz WM, Cambier JC: Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit. Science 263:1609, 1994
    • (1994) Science , vol.263 , pp. 1609
    • Pleiman, C.M.1    Hertz, W.M.2    Cambier, J.C.3
  • 55
    • 0027201616 scopus 로고
    • Granulocyte macrophage-colony stimulating factor stimulates both association and activation of phosphoinositide 3-OH kinase and src-related tyrosine kinase(s) in human myeloid derived cells
    • Corey S, Eguinoa A, Puyana Theall K, Bolen JB, Cantley L, Mollinedo TR, Jackson PT, Hawkins PT, Stephens LR: Granulocyte macrophage-colony stimulating factor stimulates both association and activation of phosphoinositide 3-OH kinase and src-related tyrosine kinase(s) in human myeloid derived cells. EMBO J 12:2681, 1993
    • (1993) EMBO J , vol.12 , pp. 2681
    • Corey, S.1    Eguinoa, A.2    Puyana Theall, K.3    Bolen, J.B.4    Cantley, L.5    Mollinedo, T.R.6    Jackson, P.T.7    Hawkins, P.T.8    Stephens, L.R.9
  • 57
    • 0029078130 scopus 로고
    • Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors
    • Petritsch C, Woscholski R, Edelmann HM, Parker PJ, Ballou LM: Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors. Eur J Biochem 230:431, 1995
    • (1995) Eur J Biochem , vol.230 , pp. 431
    • Petritsch, C.1    Woscholski, R.2    Edelmann, H.M.3    Parker, P.J.4    Ballou, L.M.5
  • 58
    • 0027436107 scopus 로고
    • FK506 and rapamycin modulate the functional activities of human peripheral blood eosinophils
    • Hom JT, Estridge T: FK506 and rapamycin modulate the functional activities of human peripheral blood eosinophils. Clin Immunol Immunopathol 68:293, 1993
    • (1993) Clin Immunol Immunopathol , vol.68 , pp. 293
    • Hom, J.T.1    Estridge, T.2
  • 60
    • 0028918408 scopus 로고
    • Rasdependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase
    • Hu Q, Klippel A, Muslin AJ, Fantl WJ, Williams LT: Rasdependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science 268:100, 1995
    • (1995) Science , vol.268 , pp. 100
    • Hu, Q.1    Klippel, A.2    Muslin, A.J.3    Fantl, W.J.4    Williams, L.T.5
  • 61
    • 0030030916 scopus 로고    scopus 로고
    • IL-5 activates a 45-kilodalton mitogen-activated protein (MAP) kinase and JAK-2 tyrosine kinase in human eosinophils
    • Bates ME, Bertics PJ, Busse WW: IL-5 activates a 45-kilodalton mitogen-activated protein (MAP) kinase and JAK-2 tyrosine kinase in human eosinophils. J Immunol 156:711, 1996
    • (1996) J Immunol , vol.156 , pp. 711
    • Bates, M.E.1    Bertics, P.J.2    Busse, W.W.3
  • 62
    • 0026345291 scopus 로고
    • Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4
    • Satoh T, Nakafuku M, Miyajima A, Kaziro Y: Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4. Proc Natl Acad Sci USA 88:3314, 1991
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3314
    • Satoh, T.1    Nakafuku, M.2    Miyajima, A.3    Kaziro, Y.4
  • 63
    • 0026671246 scopus 로고
    • Multiple hemopoietic growth factors stimulate activation of mitogenactivated protein kinase family members
    • Welham MJ, Duronio V, Sanghera JS, Pelech SL, Schrader JW: Multiple hemopoietic growth factors stimulate activation of mitogenactivated protein kinase family members. J Immunol 149:1683, 1992
    • (1992) J Immunol , vol.149 , pp. 1683
    • Welham, M.J.1    Duronio, V.2    Sanghera, J.S.3    Pelech, S.L.4    Schrader, J.W.5
  • 64
    • 0028984578 scopus 로고
    • Activation of p42mapk/erk2 following engagement of tumor necrosis factor receptor CD120a (p55) in mouse macrophages
    • Winston BW, Riches DW: Activation of p42mapk/erk2 following engagement of tumor necrosis factor receptor CD120a (p55) in mouse macrophages. J Immunol 155:1525, 1995
    • (1995) J Immunol , vol.155 , pp. 1525
    • Winston, B.W.1    Riches, D.W.2
  • 65
    • 0027162553 scopus 로고
    • Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells
    • Raines MA, Kolesnick RN, Golde DW: Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells. J Biol Chem 268:14572, 1993
    • (1993) J Biol Chem , vol.268 , pp. 14572
    • Raines, M.A.1    Kolesnick, R.N.2    Golde, D.W.3
  • 66
    • 0028225705 scopus 로고
    • Functional divergence of the MAP kinase pathway. ERK1 and ERK2 activate specific transcription factors
    • Chuang CF, Ng SY: Functional divergence of the MAP kinase pathway. ERK1 and ERK2 activate specific transcription factors. FEBS Lett 346:229, 1994
    • (1994) FEBS Lett , vol.346 , pp. 229
    • Chuang, C.F.1    Ng, S.Y.2
  • 67
    • 0028978633 scopus 로고
    • The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis
    • Faust LR, El Benna J, Babior BM, Chanock SJ: The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis. J Clin Invest 96:1499, 1995
    • (1995) J Clin Invest , vol.96 , pp. 1499
    • Faust, L.R.1    El Benna, J.2    Babior, B.M.3    Chanock, S.J.4


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