Cutting edge: Involvement of SHP-2 in multiple aspects of IL-2 signaling: Evidence for a positive regulatory role

Journal of Immunology

Volumn 160, Issue 10, 1998, Pages 4657-4661

  Gadina, Massimo ^a,c   Stancato, Louis M ^a   Bacon, Chris M ^a   Larner, Andrew C ^b   O'Shea, John J ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^c Building 10 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE PHOSPHATASE; GRB2 PROTEIN, HUMAN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; JAK3 PROTEIN, HUMAN; JANUS KINASE 3; PROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; PTPN6 PROTEIN, HUMAN; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SRC HOMOLOGY 2 (SH2) DOMAIN CONTAINING PHOSPHATASES; SRC HOMOLOGY-2 (SH2) DOMAIN-CONTAINING PHOSPHATASES;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOREGULATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; CELL CULTURE; METABOLISM; PHYSIOLOGY; TRANSACTIVATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; ENZYME ACTIVATION; GRB2 ADAPTOR PROTEIN; HUMANS; INTERLEUKIN-2; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JANUS KINASE 3; PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; PROTEINS; SHP1 PROTEIN TYROSINE PHOSPHATASE; TRANS-ACTIVATION (GENETICS);

EID: 0032523416     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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