-
1
-
-
0034890568
-
Long-term pharmacotherapy of obesity 2000: A review of efficacy and safety
-
GLAZER G: Long-term pharmacotherapy of obesity 2000: a review of efficacy and safety. Arch. Intern. Med. (2001) 161 1814-1824.
-
(2001)
Arch. Intern. Med.
, vol.161
, pp. 1814-1824
-
-
Glazer, G.1
-
2
-
-
0037298936
-
Treatment of obesity: An update on anti-obesity medications
-
HALPERN A, MANCINI MC: Treatment of obesity: an update on anti-obesity medications. Obes. Rev. (2003) 4:25-42.
-
(2003)
Obes. Rev.
, vol.4
, pp. 25-42
-
-
Halpern, A.1
Mancini, M.C.2
-
4
-
-
0036325531
-
Genetic approaches to studying energy balance: Perception and integration
-
BARSH GS, SCHWARTZ MW. Genetic approaches to studying energy balance: Perception and integration. Nat. Rev. Genet. (2002) 3 589-600.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 589-600
-
-
Barsh, G.S.1
Schwartz, M.W.2
-
5
-
-
2942716780
-
Modern science versus the stigma of obesity
-
FRIEDMAN JM: Modern science versus the stigma of obesity. Nat. Med. (2004) 10:563-569.
-
(2004)
Nat. Med.
, vol.10
, pp. 563-569
-
-
Friedman, J.M.1
-
6
-
-
0035709038
-
The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis
-
CONE RD, COWLEY MA, BUTLER AA et al.: The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis. Int. J. Obes. Relat. Metab. Disord. (2001) 25(Suppl. 5):S63-S67.
-
(2001)
Int. J. Obes. Relat. Metab. Disord.
, vol.25
, Issue.SUPPL. 5
-
-
Cone, R.D.1
Cowley, M.A.2
Butler, A.A.3
-
8
-
-
0037057755
-
Getting formal with dopamine and reward
-
SCHULTZ W. Getting formal with dopamine and reward. Neuron (2002) 36:241-263.
-
(2002)
Neuron
, vol.36
, pp. 241-263
-
-
Schultz, W.1
-
9
-
-
0032913283
-
Biochemical mechanisms responsible for the attenuation of diabetic and obese conditions in ob/ob mice treated with dopaminergic agonists
-
SCISLOWSKI PW, TOZZO E, ZHANG Y et al.: Biochemical mechanisms responsible for the attenuation of diabetic and obese conditions in ob/ob mice treated with dopaminergic agonists. Int. J. Obes. Relat. Metab. Disord. (1999) 23:425-431.
-
(1999)
Int. J. Obes. Relat. Metab. Disord.
, vol.23
, pp. 425-431
-
-
Scislowski, P.W.1
Tozzo, E.2
Zhang, Y.3
-
12
-
-
0032461050
-
Cannabinoid transmission and reward-related events
-
GARDNER EL, VOREL SR: Cannabinoid transmission and reward-related events. Neurobiol. Dis. (1998) 5:502-533.
-
(1998)
Neurobiol. Dis.
, vol.5
, pp. 502-533
-
-
Gardner, E.L.1
Vorel, S.R.2
-
13
-
-
0036669295
-
Tetrahydrocannabinol and endocannabinoids in feeding and appetite
-
BERRY EM, MECHOULAM R: Tetrahydrocannabinol and endocannabinoids in feeding and appetite. Pharmacol. Ther. (2002) 95:185-190.
-
(2002)
Pharmacol. Ther.
, vol.95
, pp. 185-190
-
-
Berry, E.M.1
Mechoulam, R.2
-
14
-
-
0032466390
-
The functional neuroanatomy of brain cannabinoid receptors
-
BREIVOGEL CS, CHILDERS SR: The functional neuroanatomy of brain cannabinoid receptors. Neurobiol Dis. (1998) 5:417-431.
-
(1998)
Neurobiol. Dis.
, vol.5
, pp. 417-431
-
-
Breivogel, C.S.1
Childers, S.R.2
-
15
-
-
0037430140
-
Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat
-
KISHI T, ASCHKENASI CJ, LEE CE et al.: Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat. J. Comp. Neurol. (2003) 457:213-235.
-
(2003)
J. Comp. Neurol.
, vol.457
, pp. 213-235
-
-
Kishi, T.1
Aschkenasi, C.J.2
Lee, C.E.3
-
16
-
-
0032889771
-
Expression of μ-, κ-, and δ-opioid receptor messenger RNA in the human CNS: A 33P in situ hybridisation study
-
PECKYS D, LANDWEHRMEYER GB: Expression of μ-, κ-, and δ-opioid receptor messenger RNA in the human CNS: a 33P in situ hybridisation study. Neuroscience (1999) 88:1093-1135.
-
(1999)
Neuroscience
, vol.88
, pp. 1093-1135
-
-
Peckys, D.1
Landwehrmeyer, G.B.2
-
17
-
-
0017668698
-
Set points, settling points and the control of body weight
-
WIRTSHAFTER D, DAVID JD: Set points, settling points and the control of body weight. Physiol. Behav. (1977) 19:75-78.
-
(1977)
Physiol. Behav.
, vol.19
, pp. 75-78
-
-
Wirtshafter, D.1
David, J.D.2
-
18
-
-
2442701355
-
Motivation concepts in behavioral neuroscience
-
BERRIDGE KC: Motivation concepts in behavioral neuroscience. Physiol. Behav. (2004) 81:179-209.
-
(2004)
Physiol. Behav.
, vol.81
, pp. 179-209
-
-
Berridge, K.C.1
-
19
-
-
0036627597
-
Multiple neural systems controlling food intake and body weight
-
BERTHOUD HR: Multiple neural systems controlling food intake and body weight. Neurosci. Biobehav. Rev. (2002) 26:393-428.
-
(2002)
Neurosci. Biobehav. Rev.
, vol.26
, pp. 393-428
-
-
Berthoud, H.R.1
-
20
-
-
0035007332
-
Opioid receptor involvement in the effect of AgRP-(83-132) on food intake and food selection
-
HAGAN MM, RUSHING PA, BENOIT SC, WOODS SC, SEELEY RJ: Opioid receptor involvement in the effect of AgRP-(83-132) on food intake and food selection. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2001) 280:R814-R821.
-
(2001)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.280
-
-
Hagan, M.M.1
Rushing, P.A.2
Benoit, S.C.3
Woods, S.C.4
Seeley, R.J.5
-
21
-
-
0035854112
-
Evidence of interactions between melanocortin and opioid systems in regulation of feeding
-
OLSZEWSKI PK, WIRTH MM, GRACE MK, LEVINE AS, GIRAUDO SQ: Evidence of interactions between melanocortin and opioid systems in regulation of feeding. Neuroreport (2001) 12:1727-1730.
-
(2001)
Neuroreport
, vol.12
, pp. 1727-1730
-
-
Olszewski, P.K.1
Wirth, M.M.2
Grace, M.K.3
Levine, A.S.4
Giraudo, S.Q.5
-
22
-
-
0029839328
-
Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction
-
ALVARO JD, TATRO JB, QUILLAN JM et al.: Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction. Mol. Pharmacol. (1996) 50:583-591.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 583-591
-
-
Alvaro, J.D.1
Tatro, J.B.2
Quillan, J.M.3
-
23
-
-
0028228615
-
Neuropeptide Y and energy balance: One way ahead for the treatment of obesity?
-
DRYDEN S, FRANKISH H, WANG Q, WILLIAMS G: Neuropeptide Y and energy balance: one way ahead for the treatment of obesity? Eur. J. Clin. Invest. (1994) 24:293-308.
-
(1994)
Eur. J. Clin. Invest.
, vol.24
, pp. 293-308
-
-
Dryden, S.1
Frankish, H.2
Wang, Q.3
Williams, G.4
-
24
-
-
0037178730
-
Activation of central melanocortin pathways by fenfluramine
-
HEISLER LK, COWLEY MA, TECOTT LH et al.: Activation of central melanocortin pathways by fenfluramine. Science (2002) 297:609-611.
-
(2002)
Science
, vol.297
, pp. 609-611
-
-
Heisler, L.K.1
Cowley, M.A.2
Tecott, L.H.3
-
25
-
-
0034264256
-
Effects of sibutramine plus orlistat in obese women following 1 year of treatment by sibutramine alone: A placebo-controlled trial
-
WADDEN TA, BERKOWITZ RI, WOMBLE LG et al.: Effects of sibutramine plus orlistat in obese women following 1 year of treatment by sibutramine alone: a placebo-controlled trial. Obes. Res. (2000) 8:431-437.
-
(2000)
Obes. Res.
, vol.8
, pp. 431-437
-
-
Wadden, T.A.1
Berkowitz, R.I.2
Womble, L.G.3
-
27
-
-
0031902759
-
1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset
-
1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset. Behav. Pharmacol. (1998) 9:179-181.
-
(1998)
Behav. Pharmacol.
, vol.9
, pp. 179-181
-
-
Simiad, J.1
Keane, M.2
Keane, P.E.3
Soubrie, P.4
-
28
-
-
0032541111
-
Appetite suppression and weight loss after the cannabinoid antagonist SR-141716
-
COLOMBO G, AGABIO R, DIAZ C, et al.: Appetite suppression and weight loss after the cannabinoid antagonist SR-141716. Life Sci. (1998) 63:113-117.
-
(1998)
Life Sci.
, vol.63
, pp. 113-117
-
-
Colombo, G.1
Agabio, R.2
Diaz, C.3
-
29
-
-
0345791451
-
Consumption of high carbohydrate, high fat, and normal chow is equally suppressed by a cannabinoid receptor antagonist in non-deprived rats
-
VERTY AN, McGREGOR IS, MALLET PE: Consumption of high carbohydrate, high fat, and normal chow is equally suppressed by a cannabinoid receptor antagonist in non-deprived rats. Neurosci. Lett. (2004) 354:217-220.
-
(2004)
Neurosci. Lett.
, vol.354
, pp. 217-220
-
-
Verty, A.N.1
McGregor, I.S.2
Mallet, P.E.3
-
30
-
-
0035543768
-
Activity of SR-141716 on post-reinforcement pauses in operant responding for sucrose reward in rats
-
PERIO A, BARNOUIN MC, PONCELET M, SOUBRIE P: Activity of SR-141716 on post-reinforcement pauses in operant responding for sucrose reward in rats. Behav. Pharmacol. (2001) 12:641-645.
-
(2001)
Behav. Pharmacol.
, vol.12
, pp. 641-645
-
-
Perio, A.1
Barnouin, M.C.2
Poncelet, M.3
Soubrie, P.4
-
31
-
-
0033585499
-
Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: A randomised controlled trial
-
DAVIDSON MH, HAUPTMAN J, DIGIROLAMO M et al.: Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomised controlled trial. JAMA (1999) 281 235-242.
-
(1999)
JAMA
, vol.281
, pp. 235-242
-
-
Davidson, M.H.1
Hauptman, J.2
Digirolamo, M.3
-
32
-
-
0034516930
-
Effect of sibutramine on weight maintenance after weight loss: A randomised trial
-
STORM Study Group. Sibutramine Trial of Obesity Reduction and Maintenance
-
JAMES WP, ASTRUP A, FINER N et al.: Effect of sibutramine on weight maintenance after weight loss: a randomised trial. STORM Study Group. Sibutramine Trial of Obesity Reduction and Maintenance. Lancet (2000) 356:2119-2125.
-
(2000)
Lancet
, vol.356
, pp. 2119-2125
-
-
James, W.P.1
Astrup, A.2
Finer, N.3
-
33
-
-
20844454912
-
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
-
BATKAI S, PACHER P, OSEI-HYIAMAN D et al.: Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation (2004) 110 1996-2002.
-
(2004)
Circulation
, vol.110
, pp. 1996-2002
-
-
Batkai, S.1
Pacher, P.2
Osei-Hyiaman, D.3
-
34
-
-
2542555018
-
The complexities of the cardiovascular actions of cannabinoids
-
RANDALL MD, KENDALL DA, O'SULLIVAN S: The complexities of the cardiovascular actions of cannabinoids. Br. J. Pharmacol. (2004) 142:20-26.
-
(2004)
Br. J. Pharmacol.
, vol.142
, pp. 20-26
-
-
Randall, M.D.1
Kendall, D.A.2
O'Sullivan, S.3
-
35
-
-
16544373950
-
Cannabinoid system as a potential target for drug development in the treatment of cardiovascular disease
-
MENDIZABAL VE, ADLER-GRASCHINSKY E: Cannabinoid system as a potential target for drug development in the treatment of cardiovascular disease. Curr. Vasc. Pharmacol. (2003) 1:301-313.
-
(2003)
Curr. Vasc. Pharmacol.
, vol.1
, pp. 301-313
-
-
Mendizabal, V.E.1
Adler-Graschinsky, E.2
-
37
-
-
0034080807
-
The ciliary neurotropic factor and its receptor, CNTFR α
-
SLEEMAN MW, ANDERSON KD, LAMBERT PD, YANCOPOULOS GD, WIEGAND SJ: The ciliary neurotropic factor and its receptor, CNTFR α. Pharm. Acta Helv. (2000) 74:265-272.
-
(2000)
Pharm. Acta Helv.
, vol.74
, pp. 265-272
-
-
Sleeman, M.W.1
Anderson, K.D.2
Lambert, P.D.3
Yancopoulos, G.D.4
Wiegand, S.J.5
-
38
-
-
0028149838
-
The tripartite CNTF receptor complex: Activation and signaling involves components shared with other cytokines
-
STAHL N, YANCOPOULOS GD: The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines. J. Neurobiol. (1994) 25:1454-1466.
-
(1994)
J. Neurobiol.
, vol.25
, pp. 1454-1466
-
-
Stahl, N.1
Yancopoulos, G.D.2
-
39
-
-
0345121142
-
Ciliary neurotropic factor corrects obesity and diabetes associated with leptin deficiency and resistance
-
GLOAGUEN I, COSTA P, DEMARTIS A et al.: Ciliary neurotropic factor corrects obesity and diabetes associated with leptin deficiency and resistance. Proc. Natl. Acad. Sci. USA (1997) 94 6456-6461.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6456-6461
-
-
Gloaguen, I.1
Costa, P.2
Demartis, A.3
-
40
-
-
0035836760
-
Ciliary neurotropic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity
-
LAMBERT PD, ANDERSON KD, SLEEMAN MW et al.: Ciliary neurotropic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity. Proc. Natl. Acad. Sci. USA (2001) 98:4652-4657.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4652-4657
-
-
Lambert, P.D.1
Anderson, K.D.2
Sleeman, M.W.3
-
41
-
-
0032900284
-
Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides
-
MARSH DJ, HOLLOPETER G, HUSZAR D et al.: Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. Nat. Genet. (1999) 21:119-122.
-
(1999)
Nat. Genet.
, vol.21
, pp. 119-122
-
-
Marsh, D.J.1
Hollopeter, G.2
Huszar, D.3
-
42
-
-
0033760590
-
Unlike leptin, ciliary neurotropic factor does not reverse the starvation-induced changes of serum corticosterone and hypothalamic neuropeptide levels but induces expression of hypothalamic inhibitors of leptin signaling
-
ZIOTOPOULOU M, ERANI DM, HILEMAN SM, BJORBAEK C, MANTZOROS CS: Unlike leptin, ciliary neurotropic factor does not reverse the starvation-induced changes of serum corticosterone and hypothalamic neuropeptide levels but induces expression of hypothalamic inhibitors of leptin signaling. Diabetes (2000) 49:1890-1896.
-
(2000)
Diabetes
, vol.49
, pp. 1890-1896
-
-
Ziotopoulou, M.1
Erani, D.M.2
Hileman, S.M.3
Bjorbaek, C.4
Mantzoros, C.S.5
-
43
-
-
0031788012
-
Anorectic effects of the cytokine, ciliary neurotropic factor, are mediated by hypothalamic neuropeptide Y: Comparison with leptin
-
XU B, DUBE MG, KALRA PS et al.: Anorectic effects of the cytokine, ciliary neurotropic factor, are mediated by hypothalamic neuropeptide Y: comparison with leptin. Endocrinology (1998) 139 466-473.
-
(1998)
Endocrinology
, vol.139
, pp. 466-473
-
-
Xu, B.1
Dube, M.G.2
Kalra, P.S.3
-
44
-
-
0034029565
-
Comparison of either norepinephrine-uptake inhibitors or phentermine combined with serotonergic agents on food intake in rats
-
ROWLAND NE, MARSHALL M, ROTH JD: Comparison of either norepinephrine-uptake inhibitors or phentermine combined with serotonergic agents on food intake in rats. Psychopharmacology (2000) 149:77-83.
-
(2000)
Psychopharmacology
, vol.149
, pp. 77-83
-
-
Rowland, N.E.1
Marshall, M.2
Roth, J.D.3
-
45
-
-
0032462875
-
The selective norepinephrine reuptake inhibitor, LY368975, reduces food consumption in animal models of feeding
-
GEHLERT DR, DRESHFIELD L, TINSLEY F et al.: The selective norepinephrine reuptake inhibitor, LY368975, reduces food consumption in animal models of feeding. J. Pharmacol. Exp. Ther. (1998) 287:122-127.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.287
, pp. 122-127
-
-
Gehlert, D.R.1
Dreshfield, L.2
Tinsley, F.3
-
46
-
-
0036636368
-
Bupropion SR enhances weight loss: A 48-week double-blind, placebo-controlled trial
-
ANDERSON JW, GREENWAY FL, FUJIOKA K et al.: Bupropion SR enhances weight loss: a 48-week double-blind, placebo-controlled trial. Obes. Res. (2002) 10:633-641.
-
(2002)
Obes. Res.
, vol.10
, pp. 633-641
-
-
Anderson, J.W.1
Greenway, F.L.2
Fujioka, K.3
-
47
-
-
0032754965
-
Cholecystokinin: Proofs and prospects for involvement in control of food intake and body weight
-
RITTER RC, COVASA M, MATSON CA: Cholecystokinin: proofs and prospects for involvement in control of food intake and body weight. Neuropeptides (1999) 33:387-399.
-
(1999)
Neuropeptides
, vol.33
, pp. 387-399
-
-
Ritter, R.C.1
Covasa, M.2
Matson, C.A.3
-
49
-
-
0032951467
-
Long-term CCK-leptin synergy suggests a role for CCK in the regulation of body weight
-
MATSON CA, RITTER RC: Long-term CCK-leptin synergy suggests a role for CCK in the regulation of body weight. Am. J. Physiol. (1999) 276:R1038-R1045.
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Matson, C.A.1
Ritter, R.C.2
-
50
-
-
1242306691
-
Analysis of the anorectic efficacy of HMR1426 in rodents and its effects on gastric emptying in rats
-
BICKEL M, GOSSEL M, GEISEN K et al.: Analysis of the anorectic efficacy of HMR1426 in rodents and its effects on gastric emptying in rats. Int. J. Obes. Relat. Metab. Disord. (2004) 28 211-221.
-
(2004)
Int. J. Obes. Relat. Metab. Disord.
, vol.28
, pp. 211-221
-
-
Bickel, M.1
Gossel, M.2
Geisen, K.3
-
51
-
-
0032940913
-
δ-9-tetrahydrocannabinol delays the gastric emptying of solid food in humans: A double-blind, randomized study
-
McCALLUM RW, SOYKAN I, SRIDHAR KR et al.: δ-9-tetrahydrocannabinol delays the gastric emptying of solid food in humans: a double-blind, randomized study. Aliment. Pharmacol. Ther. (1999) 13:77-80.
-
(1999)
Aliment Pharmacol. Ther.
, vol.13
, pp. 77-80
-
-
McCallum, R.W.1
Soykan, I.2
Sridhar, K.R.3
-
53
-
-
13544253065
-
Metabolic syndrome - A clinical and molecular perspective
-
MOLLER DM, KAUFMAN KD: Metabolic syndrome - a clinical and molecular perspective. Ann. Rev. Med. (2005) 56:45-62.
-
(2005)
Ann. Rev. Med.
, vol.56
, pp. 45-62
-
-
Moller, D.M.1
Kaufman, K.D.2
-
54
-
-
4544247230
-
Targeting metabolic syndrome
-
FONG TM: Targeting metabolic syndrome. Expert Opin. Investig. Drugs (2004) 13:1203-1206.
-
(2004)
Expert Opin. Investig. Drugs
, vol.13
, pp. 1203-1206
-
-
Fong, T.M.1
-
55
-
-
0033891368
-
Obesity: An epidemic in need of therapeutics
-
VAN DER PLOEG LH: Obesity: an epidemic in need of therapeutics. Curr. Opin. Chem. Biol. (2000) 4:452-460.
-
(2000)
Curr. Opin. Chem. Biol.
, vol.4
, pp. 452-460
-
-
Van Der Ploeg, L.H.1
-
57
-
-
0037456768
-
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
-
FAROOQI IS, KEOGH JM, YEO GS et al.: Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N. Engl. J. Med. (2003) 348:1085-1095.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1085-1095
-
-
Farooqi, I.S.1
Keogh, J.M.2
Yeo, G.S.3
-
58
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
HUSZAR D, LYNCH CA, FAIR-HUNTRESS V et al.: Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell (1997) 88:131-141.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fair-Huntress, V.3
-
61
-
-
0036443705
-
Chronic infusion of a melanocortin receptor agonist modulates dopamine receptor binding in the rat brain
-
LINDBLOM J, KASK A, HAGG E et al.: Chronic infusion of a melanocortin receptor agonist modulates dopamine receptor binding in the rat brain. Pharmacol. Res. (2002) 45:119-124.
-
(2002)
Pharmacol. Res.
, vol.45
, pp. 119-124
-
-
Lindblom, J.1
Kask, A.2
Hagg, E.3
-
62
-
-
0036235622
-
The melanocortin receptor agonist MTII augments the rewarding effect of amphetamine in ad-libitum-fed and food-restricted rats
-
CABEZA DE VACA S, KIM G, CARR KD: The melanocortin receptor agonist MTII augments the rewarding effect of amphetamine in ad-libitum-fed and food-restricted rats. Psychopharmacology (2002) 161:77-85.
-
(2002)
Psychopharmacology
, vol.161
, pp. 77-85
-
-
Cabeza De Vaca, S.1
Kim, G.2
Carr, K.D.3
-
63
-
-
1642414475
-
Melanocortin-4 receptor agonists and antagonists: Chemistry and potential therapeutic utilities
-
SEBHAT I, YE Z, BEDNAREK M et al.: Melanocortin-4 receptor agonists and antagonists: chemistry and potential therapeutic utilities. Ann. Rep. Med. Chem. (2003) 38:31-40.
-
(2003)
Ann. Rep. Med. Chem.
, vol.38
, pp. 31-40
-
-
Sebhat, I.1
Ye, Z.2
Bednarek, M.3
-
64
-
-
0035912709
-
Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R
-
SAILER AW, SANO H, ZENG Z et al.: Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc. Natl. Acad. Sci. USA (2001) 98:7564-7569.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7564-7569
-
-
Sailer, A.W.1
Sano, H.2
Zeng, Z.3
-
65
-
-
0033566084
-
Molecular characterization of the melanin-concentrating-hormone receptor
-
SAITO Y, NOTHACKER HP, WANG Z et al.: Molecular characterization of the melanin-concentrating-hormone receptor. Nature (1999) 400:265-269.
-
(1999)
Nature
, vol.400
, pp. 265-269
-
-
Saito, Y.1
Nothacker, H.P.2
Wang, Z.3
-
66
-
-
0032542294
-
Mice lacking melanin-concentrating hormone are hypophagic and lean
-
SHIMADA M, TRITOS NA, LOWELL BB, FLIER JS, MARATOS-FLIER E: Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature (1998) 396:670-674.
-
(1998)
Nature
, vol.396
, pp. 670-674
-
-
Shimada, M.1
Tritos, N.A.2
Lowell, B.B.3
Flier, J.S.4
Maratos-Flier, E.5
-
67
-
-
0037022667
-
Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive and hyperphagic and have altered metabolism
-
MARSH DJ, WEINGARTH DT, NOVI DE et al.: Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive and hyperphagic and have altered metabolism. Proc. Natl. Acad. Sci. USA (2002) 99:3240-3245.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3240-3245
-
-
Marsh, D.J.1
Weingarth, D.T.2
Novi, D.E.3
-
68
-
-
18444375866
-
Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity
-
CHEN Y, HU C, HSU CK et al.: Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity. Endocrinology (2002) 143 2469-2477.
-
(2002)
Endocrinology
, vol.143
, pp. 2469-2477
-
-
Chen, Y.1
Hu, C.2
Hsu, C.K.3
-
69
-
-
4544374046
-
Therapeutic potential of melanin-concentrating hormone-1 receptor antagonists for the treatment of obesity
-
KOWALSKI TJ, McBRIAR MD: Therapeutic potential of melanin-concentrating hormone-1 receptor antagonists for the treatment of obesity. Expert Opin. Investig. Drugs (2004) 13:1113-1122.
-
(2004)
Expert Opin. Investig. Drugs
, vol.13
, pp. 1113-1122
-
-
Kowalski, T.J.1
McBriar, M.D.2
-
70
-
-
0027489212
-
Long-term treatment of obese Zucker rats with LY255582 and other appetite suppressants
-
SHAW WN: Long-term treatment of obese Zucker rats with LY255582 and other appetite suppressants. Pharmacol. Biochem. Behav. (1993) 46:653-659.
-
(1993)
Pharmacol. Biochem. Behav.
, vol.46
, pp. 653-659
-
-
Shaw, W.N.1
-
71
-
-
0032750456
-
Opioids and food intake: Distributed functional neural pathways?
-
GLASS M, BILLINGTON CJ, LEVINE AS: Opioids and food intake: distributed functional neural pathways? Neuropeptides (1999) 33 360-368.
-
(1999)
Neuropeptides
, vol.33
, pp. 360-368
-
-
Glass, M.1
Billington, C.J.2
Levine, A.S.3
-
72
-
-
0038515754
-
Peptides that regulate food intake: Antagonism of opioid receptors reduces body fat in obese rats by decreasing food intake and stimulating lipid utilization
-
STATNICK MA, TINSLEY FC, EASTWOOD BJ et al.: Peptides that regulate food intake: antagonism of opioid receptors reduces body fat in obese rats by decreasing food intake and stimulating lipid utilization. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2003) 284:R1399-R1408.
-
(2003)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.284
-
-
Statnick, M.A.1
Tinsley, F.C.2
Eastwood, B.J.3
-
73
-
-
2542460126
-
Endogenous opioids and feeding behavior: A 30-year historical perspective
-
BODNAR RJ: Endogenous opioids and feeding behavior: a 30-year historical perspective. Peptides (2004) 25:697-725.
-
(2004)
Peptides
, vol.25
, pp. 697-725
-
-
Bodnar, R.J.1
-
74
-
-
0029566187
-
Metabolic determinants of binge eating
-
DREWNOWSKI A: Metabolic determinants of binge eating. Addictive Behav. (1995) 20:733-745.
-
(1995)
Addictive Behav.
, vol.20
, pp. 733-745
-
-
Drewnowski, A.1
-
75
-
-
0027079916
-
Opiate antagonists and eating behaviour in humans: A review
-
DE ZWAAN M, MITCHELL JE: Opiate antagonists and eating behaviour in humans: a review. J. Clin. Pharmacol. (1992) 32 1060-1072.
-
(1992)
J. Clin. Pharmacol.
, vol.32
, pp. 1060-1072
-
-
De Zwaan, M.1
Mitchell, J.E.2
-
76
-
-
0030659004
-
Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system
-
KIM S, WAGNER HN, VILLEMAGNE VL et al.: Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system. J. Nuc. Med. (1997) 38:1726-1731.
-
(1997)
J. Nuc. Med.
, vol.38
, pp. 1726-1731
-
-
Kim, S.1
Wagner, H.N.2
Villemagne, V.L.3
-
77
-
-
3042631016
-
Chronic administration of nalmefene leads to increased food intake and body weight gain in mice
-
CHEN RZ, HUANG RR, SHEN CP, MACNEIL DJ, FONG TM: Chronic administration of nalmefene leads to increased food intake and body weight gain in mice. Eur. J. Pharmacol. (2004) 495:63-66.
-
(2004)
Eur. J. Pharmacol.
, vol.495
, pp. 63-66
-
-
Chen, R.Z.1
Huang, R.R.2
Shen, C.P.3
Macneil, D.J.4
Fong, T.M.5
-
78
-
-
0026664550
-
Microinjection of opioid antagonists into the substantia nigra reduces stress-induced eating in rats
-
HAWKINS MF, CUBIC B, BAUMEISTER AA, BARTON C: Microinjection of opioid antagonists into the substantia nigra reduces stress-induced eating in rats. Brain Res. (1992) 584:261-265.
-
(1992)
Brain Res.
, vol.584
, pp. 261-265
-
-
Hawkins, M.F.1
Cubic, B.2
Baumeister, A.A.3
Barton, C.4
-
79
-
-
0036826863
-
Combined blockade of both μ-and κ-opioid receptors prevents the acute orexigenic action of agouti-related protein
-
BRUGMAN S, CLEGG DJ, WOODS SC, SEELEY RJ: Combined blockade of both μ-and κ-opioid receptors prevents the acute orexigenic action of agouti-related protein. Endocrinology (2002) 143 4265-4270.
-
(2002)
Endocrinology
, vol.143
, pp. 4265-4270
-
-
Brugman, S.1
Clegg, D.J.2
Woods, S.C.3
Seeley, R.J.4
-
80
-
-
0038779278
-
3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro
-
SETOLA V, HUFEISEN SJ, GRANDE-ALLEN KJ et al.: 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro. Mol. Pharmacol. (2003) 63 1223-1229.
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 1223-1229
-
-
Setola, V.1
Hufeisen, S.J.2
Grande-Allen, K.J.3
-
81
-
-
0028959193
-
Changes in energy expenditure resulting from altered body weight
-
LEIBEL RL, ROSENBAUM M, HIRSCH J: Changes in energy expenditure resulting from altered body weight. N. Engl. J. Med. (1995) 332:621-628.
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 621-628
-
-
Leibel, R.L.1
Rosenbaum, M.2
Hirsch, J.3
|