Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction

Molecular Pharmacology

Volumn 50, Issue 3, 1996, Pages 583-591

  Alvaro, John D ^a   Tatro, Jeffrey B ^b   Quillan, J Mark ^a   Fogliano, Michael ^c   Eisenhard, Michael ^c   Lerner, Michael R ^a   Nestler, Eric J ^a   Duman, Ronald S ^a,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^d Yale University School of Medicine and the Connecticut Mental Health Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; CORTICOTROPIN; GAMMA INTERMEDIN; HORMONE RECEPTOR; INTERMEDIN DERIVATIVE; MORPHINE DERIVATIVE; OPIATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; DRUG TOLERANCE; MALE; NONHUMAN; NUCLEUS ACCUMBENS; OPIATE ADDICTION; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR DOWN REGULATION;

ANIMALS; AUTORADIOGRAPHY; BASE SEQUENCE; BRAIN; BRAIN MAPPING; CLONING, MOLECULAR; CONSERVED SEQUENCE; CYCLIC AMP; DNA PRIMERS; DOWN-REGULATION; DRUG TOLERANCE; GENE LIBRARY; HUMANS; IODINE RADIOISOTOPES; KINETICS; MICE; MOLECULAR SEQUENCE DATA; MORPHINE; MORPHINE DEPENDENCE; NUCLEUS ACCUMBENS; OLFACTORY PATHWAYS; OPIOID-RELATED DISORDERS; ORGAN SPECIFICITY; POLYMERASE CHAIN REACTION; RATS; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, PEPTIDE; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS;

EID: 0029839328     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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