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Volumn 281, Issue 3, 1999, Pages 235-242

Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: A randomized controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TETRAHYDROLIPSTATIN;

EID: 0033585499     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.281.3.235     Document Type: Article
Times cited : (872)

References (30)
  • 3
    • 10544235698 scopus 로고    scopus 로고
    • Long-term pharmacotherapy in the management of obesity
    • National Task Force on the Prevention and Treatment of Obesity. Long-term pharmacotherapy in the management of obesity. JAMA. 1996;276:1907-1915.
    • (1996) JAMA , vol.276 , pp. 1907-1915
  • 4
    • 0030705157 scopus 로고    scopus 로고
    • Obesity and heart disease
    • Eckel RH. Obesity and heart disease. Circulation. 1997;96:3248-3250.
    • (1997) Circulation , vol.96 , pp. 3248-3250
    • Eckel, R.H.1
  • 5
    • 0032055822 scopus 로고    scopus 로고
    • Metabolic risk factors worsen continuously across the spectrum of nondiabetic glucose tolerance
    • Meigs J, Nathan D, Wilson P, Cupples L, Singer D. Metabolic risk factors worsen continuously across the spectrum of nondiabetic glucose tolerance. Ann Intern Med. 1998;128:524-533.
    • (1998) Ann Intern Med. , vol.128 , pp. 524-533
    • Meigs, J.1    Nathan, D.2    Wilson, P.3    Cupples, L.4    Singer, D.5
  • 6
    • 0027437262 scopus 로고
    • Medical hazards of obesity
    • Pi-Sunyer FX. Medical hazards of obesity. Ann Intern Med. 1993;19:655-660.
    • (1993) Ann Intern Med. , vol.19 , pp. 655-660
    • Pi-Sunyer, F.X.1
  • 8
    • 0028901989 scopus 로고
    • Orlistat (Ro 18-0647), a lipase inhibitor, in the treatment of human obesity: A multiple dose study
    • Drent ML, Larsson I, William-Olsson T, et al. Orlistat (Ro 18-0647), a lipase inhibitor, in the treatment of human obesity: a multiple dose study. Int J Obes Relat Metab Disord. 1995;19:221-226.
    • (1995) Int J Obes Relat Metab Disord. , vol.19 , pp. 221-226
    • Drent, M.L.1    Larsson, I.2    William-Olsson, T.3
  • 9
    • 0026753155 scopus 로고
    • Beneficial health effects of modest weight loss
    • Goldstein DJ. Beneficial health effects of modest weight loss. Int J Obes Relat Metab Disord. 1992;16:397-415.
    • (1992) Int J Obes Relat Metab Disord. , vol.16 , pp. 397-415
    • Goldstein, D.J.1
  • 11
    • 0018602014 scopus 로고
    • Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance
    • National Diabetes Data Group. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes. 1979;28:1039-1057.
    • (1979) Diabetes , vol.28 , pp. 1039-1057
  • 12
    • 9444255722 scopus 로고    scopus 로고
    • Improving the quality of reporting of randomized controlled trials
    • Begg C, Cho M, Eastwood S, et al. Improving the quality of reporting of randomized controlled trials. JAMA. 1996;276:637-639.
    • (1996) JAMA , vol.276 , pp. 637-639
    • Begg, C.1    Cho, M.2    Eastwood, S.3
  • 14
    • 0032543870 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients
    • Sjöström L, Rissanen A, Andersen T, et al. Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. Lancet. 1998;352:167-173.
    • (1998) Lancet , vol.352 , pp. 167-173
    • Sjöström, L.1    Rissanen, A.2    Andersen, T.3
  • 15
    • 0028959193 scopus 로고
    • Changes in energy expenditure resulting from altered body weight
    • Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med. 1995;332:621-628.
    • (1995) N Engl J Med. , vol.332 , pp. 621-628
    • Leibel, R.L.1    Rosenbaum, M.2    Hirsch, J.3
  • 16
    • 0029401553 scopus 로고
    • Evaluation of drugs for treating obesity
    • Bray G. Evaluation of drugs for treating obesity. Obes Res. 1995;3(suppl 4):425S-434S.
    • (1995) Obes Res. , vol.3 , Issue.4 SUPPL.
    • Bray, G.1
  • 19
    • 0026593859 scopus 로고
    • Long-term weight control study: Conclusions
    • Weintraub M. Long-term weight control study: conclusions. Clin Pharmacol Ther. 1992;51:642-646.
    • (1992) Clin Pharmacol Ther. , vol.51 , pp. 642-646
    • Weintraub, M.1
  • 20
    • 0031909881 scopus 로고    scopus 로고
    • Lifestyle intervention in overweight individuals with a family history of diabetes
    • Wing R, Venditti E, Jakicic J, et al. Lifestyle intervention in overweight individuals with a family history of diabetes. Diabetes Care. 1998;21:350-360.
    • (1998) Diabetes Care , vol.21 , pp. 350-360
    • Wing, R.1    Venditti, E.2    Jakicic, J.3
  • 21
    • 0028147295 scopus 로고
    • Caloric restriction per se is a significant factor in improvements in glycemic control and insulin sensitivity during weight loss in obese NIDDM patients
    • Wing R, Blair E, Bononi P, et al. Caloric restriction per se is a significant factor in improvements in glycemic control and insulin sensitivity during weight loss in obese NIDDM patients. Diabetes Care. 1994;17:30-36.
    • (1994) Diabetes Care , vol.17 , pp. 30-36
    • Wing, R.1    Blair, E.2    Bononi, P.3
  • 23
    • 0344435474 scopus 로고    scopus 로고
    • Atherogenic dyslipidemia and the metabolic syndrome
    • Gotto AJ, ed. Norwell, Mass: Kluwer Academic Publishers
    • Grundy S. Atherogenic dyslipidemia and the metabolic syndrome. In: Gotto AJ, ed. Drugs Affecting Lipid Metabolism. Norwell, Mass: Kluwer Academic Publishers; 1996:237-247.
    • (1996) Drugs Affecting Lipid Metabolism , pp. 237-247
    • Grundy, S.1
  • 24
    • 0029862973 scopus 로고    scopus 로고
    • Hyperinsulinemia as an independent risk factor for ischemic heart disease
    • Despres J, Lamarche B, Mauriege P, et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med. 1996;334:952-957.
    • (1996) N Engl J Med. , vol.334 , pp. 952-957
    • Despres, J.1    Lamarche, B.2    Mauriege, P.3
  • 25
    • 0000556282 scopus 로고
    • Hyperinsulinemia
    • Landsberg L. Hyperinsulinemia. Hypertension. 1992;(suppl)19:161-166.
    • (1992) Hypertension , vol.19 , Issue.SUPPL. , pp. 161-166
    • Landsberg, L.1
  • 26
  • 27
    • 85069028197 scopus 로고    scopus 로고
    • NDA 20-766, xenical (Orlistat)
    • March Gaithersburg, Md.
    • Food and Drug Administration, Centerfor Drug Evaluation and Research. NDA 20-766, Xenical (Orlistat). Presented at: Endocrinologic and Metabolic Drugs Advisory Committee Meeting 69; March 1998; Gaithersburg, Md.
    • (1998) Endocrinologic and Metabolic Drugs Advisory Committee Meeting 69
  • 28
    • 0028866609 scopus 로고
    • Review of limited systemic absorption of orlistat, a lipase inhibitor, in healthy human volunteers
    • Zhi J, Melia AT, Eggers H, Joly R, Patel IH. Review of limited systemic absorption of orlistat, a lipase inhibitor, in healthy human volunteers. J Clin Pharmacol. 1995;35:1103-1108.
    • (1995) J Clin Pharmacol. , vol.35 , pp. 1103-1108
    • Zhi, J.1    Melia, A.T.2    Eggers, H.3    Joly, R.4    Patel, I.H.5
  • 29
    • 0008040074 scopus 로고    scopus 로고
    • Design and analysis of obesity treatment and prevention trials
    • Dalton S, ed. Gaithersburg, Md: Aspen Publishers Inc
    • Ailison DB, Cappelleri JC, Carpenter KM. Design and analysis of obesity treatment and prevention trials. In: Dalton S, ed. Overweight and Weight Management. Gaithersburg, Md: Aspen Publishers Inc; 1997:557-597.
    • (1997) Overweight and Weight Management , pp. 557-597
    • Ailison, D.B.1    Cappelleri, J.C.2    Carpenter, K.M.3
  • 30
    • 0030460385 scopus 로고    scopus 로고
    • Intent-to-treat analysis for longitudinal studies with dropouts
    • Little R, Yau L. Intent-to-treat analysis for longitudinal studies with dropouts. Biometrics. 1996;52: 1324-1333.
    • (1996) Biometrics , vol.52 , pp. 1324-1333
    • Little, R.1    Yau, L.2


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